CH1196397H1 - Metabotrope Glutamatrezeptorantagonisten zur Behandlung von Krankheiten des zentralen Nervensystems. - Google Patents

Metabotrope Glutamatrezeptorantagonisten zur Behandlung von Krankheiten des zentralen Nervensystems. Download PDF

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Publication number
CH1196397H1
CH1196397H1 CH00936465T CH00936465T CH1196397H1 CH 1196397 H1 CH1196397 H1 CH 1196397H1 CH 00936465 T CH00936465 T CH 00936465T CH 00936465 T CH00936465 T CH 00936465T CH 1196397 H1 CH1196397 H1 CH 1196397H1
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Switzerland
Prior art keywords
diseases
metabotropic glutamate
treatment
nervous system
central nervous
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CH00936465T
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English (en)
Inventor
Bradford C Van Wagenen
Scott T Moe
Daryl L Smith
Susan M Sheehan
Irina Shcherbakova
Richard Travato
Ruth Walton
Robert Barmore
Eric G Delmar
Thomas M Stormann
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Nps Pharma Inc
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Publication of CH1196397H1 publication Critical patent/CH1196397H1/de

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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CH00936465T 1999-06-02 2000-06-02 Metabotrope Glutamatrezeptorantagonisten zur Behandlung von Krankheiten des zentralen Nervensystems. CH1196397H1 (de)

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AU2005200633A1 (en) 2005-03-17
EP1196397A1 (de) 2002-04-17
AU778063C (en) 2005-12-15
EP1595871A3 (de) 2005-11-30
CA2376024A1 (en) 2000-12-07
CN1361768A (zh) 2002-07-31
EP1196397B1 (de) 2005-08-17
DE60022050C5 (de) 2007-10-11
DK1196397T3 (da) 2006-01-02
NZ515894A (en) 2003-09-26
MXPA01012445A (es) 2003-09-10
EP1595871A2 (de) 2005-11-16
IL146871A0 (en) 2002-08-14
DE60022050T2 (de) 2006-06-14
HK1048635A1 (zh) 2003-04-11
AU5178000A (en) 2000-12-18
ES2249272T3 (es) 2006-04-01
WO2000073283A1 (en) 2000-12-07
CN1789246A (zh) 2006-06-21
AU778063B2 (en) 2004-11-11
JP2003500480A (ja) 2003-01-07
ATE302194T1 (de) 2005-09-15
DE60022050D1 (de) 2005-09-22

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