MXPA01012445A - Antagonistas de receptor metabotropico de glutamato, y su uso para tratar enfermedades del sistema nervioso central. - Google Patents
Antagonistas de receptor metabotropico de glutamato, y su uso para tratar enfermedades del sistema nervioso central.Info
- Publication number
- MXPA01012445A MXPA01012445A MXPA01012445A MXPA01012445A MXPA01012445A MX PA01012445 A MXPA01012445 A MX PA01012445A MX PA01012445 A MXPA01012445 A MX PA01012445A MX PA01012445 A MXPA01012445 A MX PA01012445A MX PA01012445 A MXPA01012445 A MX PA01012445A
- Authority
- MX
- Mexico
- Prior art keywords
- metabotropic glutamate
- nervous system
- central nervous
- receptor antagonists
- glutamate receptor
- Prior art date
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13727299P | 1999-06-02 | 1999-06-02 | |
PCT/US2000/015222 WO2000073283A1 (en) | 1999-06-02 | 2000-06-02 | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases |
Publications (1)
Publication Number | Publication Date |
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MXPA01012445A true MXPA01012445A (es) | 2003-09-10 |
Family
ID=22476587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01012445A MXPA01012445A (es) | 1999-06-02 | 2000-06-02 | Antagonistas de receptor metabotropico de glutamato, y su uso para tratar enfermedades del sistema nervioso central. |
Country Status (15)
Country | Link |
---|---|
EP (2) | EP1595871A3 (es) |
JP (1) | JP2003500480A (es) |
CN (2) | CN1789246A (es) |
AT (1) | ATE302194T1 (es) |
AU (2) | AU778063C (es) |
CA (1) | CA2376024A1 (es) |
CH (1) | CH1196397H1 (es) |
DE (1) | DE60022050C5 (es) |
DK (1) | DK1196397T3 (es) |
ES (1) | ES2249272T3 (es) |
HK (1) | HK1048635A1 (es) |
IL (1) | IL146871A0 (es) |
MX (1) | MXPA01012445A (es) |
NZ (1) | NZ515894A (es) |
WO (1) | WO2000073283A1 (es) |
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DE10124953A1 (de) * | 2001-05-21 | 2002-12-12 | Marlies Knipper | Substanz für die therapeutische Behandlung von Tinnitus |
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DE10153345A1 (de) * | 2001-10-29 | 2003-05-08 | Gruenenthal Gmbh | Substituierte 1H-Chinoxalin-2-on-Verbindungen und substituierte 4-Aryl- und 4-Heteroarylcyclohexan-Verbindungen |
ES2316777T3 (es) * | 2002-02-15 | 2009-04-16 | Glaxo Group Limited | Moduladores de receptores vainilloides. |
TWI314041B (en) * | 2002-10-21 | 2009-09-01 | Sankyo Agro Co Ltd | Quinolyl-3-carboxamide compound |
CA2513824A1 (en) * | 2003-01-31 | 2004-08-19 | Astrazeneca Ab | Saturated quinoxaline derivatives and their use as metabotropic glutamate receptor ligands |
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JP2009519986A (ja) * | 2005-12-20 | 2009-05-21 | ノバルティス アクチエンゲゼルシャフト | 代謝型グルタミン酸受容体のモジュレーターとしてのニコチン酸誘導体 |
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WO2012054724A1 (en) | 2010-10-21 | 2012-04-26 | Massachusetts Institute Of Technology | Methods of treating seizure disorders |
CN103298810B (zh) | 2010-11-08 | 2016-03-16 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
JP5852665B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
CA2815002C (en) | 2010-11-08 | 2019-10-22 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
JP5617799B2 (ja) * | 2010-12-07 | 2014-11-05 | 信越化学工業株式会社 | 化学増幅レジスト材料及びパターン形成方法 |
TWI538905B (zh) | 2010-12-22 | 2016-06-21 | H 朗德貝克公司 | 雙環[3.2.1]辛基醯胺衍生物及其用途 |
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JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
JP6629740B2 (ja) | 2014-01-21 | 2020-01-15 | ヤンセン ファーマシューティカ エヌ.ベー. | 代謝型グルタミン酸作動性受容体サブタイプ2の正のアロステリック調節因子またはオルトステリックアゴニストを含む組み合わせ、およびそれらの使用 |
KR20200036063A (ko) | 2014-01-21 | 2020-04-06 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
KR102529578B1 (ko) | 2014-08-29 | 2023-05-09 | (주)아모레퍼시픽 | 신규 아다만탄 유도체 화합물 |
CN104860901B (zh) * | 2015-04-20 | 2017-04-19 | 北京工业大学 | 一种苯并噻唑‑2‑羧酸的制备方法 |
KR20180095580A (ko) * | 2015-12-17 | 2018-08-27 | 아스텍스 테라퓨틱스 리미티드 | H-pgds 억제제로서의 퀴놀린-3-카르복스아미드 |
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CN111269203A (zh) * | 2018-12-04 | 2020-06-12 | 上海中泽医药科技有限公司 | N-环己基-呋喃-2-甲酰胺类化合物及制法和应用 |
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NZ505207A (en) * | 1997-11-21 | 2003-10-31 | Nps Pharma Inc | Metabotropic glutamate receptor antagonists for treating central nervous system diseases |
-
2000
- 2000-06-02 CN CNA2005101186507A patent/CN1789246A/zh active Pending
- 2000-06-02 MX MXPA01012445A patent/MXPA01012445A/es active IP Right Grant
- 2000-06-02 WO PCT/US2000/015222 patent/WO2000073283A1/en active IP Right Grant
- 2000-06-02 AT AT00936465T patent/ATE302194T1/de not_active IP Right Cessation
- 2000-06-02 DE DE60022050T patent/DE60022050C5/de not_active Expired - Fee Related
- 2000-06-02 IL IL14687100A patent/IL146871A0/xx unknown
- 2000-06-02 JP JP2000621349A patent/JP2003500480A/ja active Pending
- 2000-06-02 AU AU51780/00A patent/AU778063C/en not_active Ceased
- 2000-06-02 EP EP05017791A patent/EP1595871A3/en not_active Withdrawn
- 2000-06-02 NZ NZ515894A patent/NZ515894A/xx unknown
- 2000-06-02 CN CN00810658A patent/CN1361768A/zh active Pending
- 2000-06-02 ES ES00936465T patent/ES2249272T3/es not_active Expired - Lifetime
- 2000-06-02 CA CA002376024A patent/CA2376024A1/en not_active Abandoned
- 2000-06-02 DK DK00936465T patent/DK1196397T3/da active
- 2000-06-02 EP EP00936465A patent/EP1196397B1/en not_active Expired - Lifetime
- 2000-06-02 CH CH00936465T patent/CH1196397H1/de unknown
-
2003
- 2003-01-30 HK HK03100778.5A patent/HK1048635A1/zh unknown
-
2005
- 2005-02-11 AU AU2005200633A patent/AU2005200633A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2005200633A1 (en) | 2005-03-17 |
HK1048635A1 (zh) | 2003-04-11 |
DE60022050D1 (de) | 2005-09-22 |
WO2000073283A1 (en) | 2000-12-07 |
NZ515894A (en) | 2003-09-26 |
IL146871A0 (en) | 2002-08-14 |
CA2376024A1 (en) | 2000-12-07 |
ATE302194T1 (de) | 2005-09-15 |
EP1595871A3 (en) | 2005-11-30 |
DE60022050T2 (de) | 2006-06-14 |
CH1196397H1 (de) | 2007-05-31 |
EP1196397B1 (en) | 2005-08-17 |
EP1196397A1 (en) | 2002-04-17 |
DK1196397T3 (da) | 2006-01-02 |
CN1361768A (zh) | 2002-07-31 |
JP2003500480A (ja) | 2003-01-07 |
DE60022050C5 (de) | 2007-10-11 |
CN1789246A (zh) | 2006-06-21 |
AU778063B2 (en) | 2004-11-11 |
AU5178000A (en) | 2000-12-18 |
AU778063C (en) | 2005-12-15 |
EP1595871A2 (en) | 2005-11-16 |
ES2249272T3 (es) | 2006-04-01 |
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