US4851423A
(en)
|
1986-12-10 |
1989-07-25 |
Schering Corporation |
Pharmaceutically active compounds
|
MX9200299A
(es)
|
1991-02-07 |
1992-12-01 |
Roussel Uclaf |
Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
|
EP2223920A3
(en)
|
1996-06-19 |
2011-09-28 |
Aventis Pharma Limited |
Substituted azabicyclic compounds
|
US5733912A
(en)
|
1997-02-19 |
1998-03-31 |
Abbott Laboratories |
7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
|
CA2304473A1
(en)
|
1997-09-29 |
1999-04-22 |
Rajeev S. Bhide |
Inhibitors of farnesyl protein transferase
|
KR20010052570A
(ko)
|
1998-06-04 |
2001-06-25 |
스티븐 에프. 웨인스톡 |
세포 유착을 억제하는 소염성 화합물
|
US6232320B1
(en)
|
1998-06-04 |
2001-05-15 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
WO2000075145A1
(en)
|
1999-06-03 |
2000-12-14 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
AU6076000A
(en)
|
1999-07-30 |
2001-02-19 |
Vertex Pharmaceuticals Incorporated |
Cyclic amine derivatives for the treatment of neurological diseases
|
WO2001014336A1
(fr)
|
1999-08-20 |
2001-03-01 |
Nippon Kayaku Kabushiki Kaisha |
Derives benzeniques substitues par un cycle aromatique, et leur procede de production
|
WO2001098301A1
(fr)
|
2000-06-20 |
2001-12-27 |
Japan Tobacco Inc. |
Composes de pyrazolopyridine et utilisation de ces derniers en tant que medicaments
|
GB0021885D0
(en)
|
2000-09-06 |
2000-10-18 |
Fujisawa Pharmaceutical Co |
New use
|
DE10046029A1
(de)
|
2000-09-18 |
2002-03-28 |
Bayer Ag |
Indazole
|
EP1217000A1
(en)
|
2000-12-23 |
2002-06-26 |
Aventis Pharma Deutschland GmbH |
Inhibitors of factor Xa and factor VIIa
|
DK1370260T3
(da)
|
2001-02-20 |
2011-03-14 |
Chugai Pharmaceutical Co Ltd |
Azoler, som malonyl-coa-decarboxylaseinhibitorer anvendelige som mataboliske modulatorer
|
JP4176477B2
(ja)
|
2001-03-01 |
2008-11-05 |
塩野義製薬株式会社 |
Hivインテグラーゼ阻害活性を有する含窒素芳香族複素環誘導体
|
CA2443697A1
(en)
|
2001-04-13 |
2002-10-24 |
Pier F. Cirillo |
1,4-disubstituted benzo-fused compounds
|
WO2002096426A1
(en)
|
2001-05-25 |
2002-12-05 |
Bristol-Myers Squibb Company |
Hydantion derivatives as inhibitors of matrix metalloproteinases
|
AU2002322585A1
(en)
|
2001-07-20 |
2003-03-03 |
Adipogenix, Inc. |
Fat accumulation-modulating compounds
|
US7294624B2
(en)
|
2001-12-20 |
2007-11-13 |
Bristol Myers Squibb Company |
Barbituric acid derivatives as inhibitors of TNF-α converting enzyme (TACE) and/or matrix metalloproteinases
|
US20030236277A1
(en)
|
2002-02-14 |
2003-12-25 |
Kadow John F. |
Indole, azaindole and related heterocyclic pyrrolidine derivatives
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
JP3812678B2
(ja)
|
2002-04-25 |
2006-08-23 |
小野薬品工業株式会社 |
ジケトヒドラジン誘導体化合物およびその化合物を有効成分として含有する薬剤
|
WO2004024705A1
(ja)
|
2002-09-10 |
2004-03-25 |
Takeda Pharmaceutical Company Limited |
5員複素環化合物
|
MXPA05002745A
(es)
|
2002-09-13 |
2005-06-03 |
Synta Pharmaceuticals Corp |
Sintesis de indolizinas.
|
AU2003272879A1
(en)
|
2002-09-18 |
2004-04-08 |
Ono Pharmaceutical Co., Ltd. |
Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
|
WO2004035581A1
(ja)
|
2002-10-18 |
2004-04-29 |
Ono Pharmaceutical Co., Ltd. |
スピロ複素環誘導体化合物およびその化合物を有効成分とする薬剤
|
WO2004050613A2
(en)
|
2002-12-02 |
2004-06-17 |
Gilead Sciences, Inc. |
2-substituted-3-propenamide derivatives and methods of using the same
|
US7320989B2
(en)
|
2003-02-28 |
2008-01-22 |
Encysive Pharmaceuticals, Inc. |
Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
|
EP1601678A2
(en)
|
2003-03-13 |
2005-12-07 |
Synta Pharmaceuticals Corporation |
Fused pyrrole compounds
|
EP1479676A1
(en)
|
2003-05-19 |
2004-11-24 |
Aventis Pharma Deutschland GmbH |
Benzimidazole-derivatives as factor xa inhibitors
|
MXPA06002853A
(es)
|
2003-09-11 |
2006-06-14 |
Kemia Inc |
Inhibidores citoquina.
|
WO2005033072A2
(en)
|
2003-09-30 |
2005-04-14 |
Scios Inc. |
Heterocyclic amides and sulfonamides
|
WO2005040133A1
(en)
|
2003-10-23 |
2005-05-06 |
Pharmacia Corporation |
Pyrimidine compounds for the treatment of inflammation
|
AU2004283751B2
(en)
|
2003-10-24 |
2011-05-19 |
Exelixis, Inc. |
p70S6 kinase modulators and method of use
|
US7049307B2
(en)
|
2003-12-23 |
2006-05-23 |
Abbott Laboratories |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US20050137187A1
(en)
|
2003-12-23 |
2005-06-23 |
Souers Andrew J. |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US20050137243A1
(en)
|
2003-12-23 |
2005-06-23 |
Souers Andrew J. |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US7071182B2
(en)
|
2003-12-23 |
2006-07-04 |
Abbott Laboratories |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
CA2557247A1
(en)
|
2004-02-27 |
2005-09-22 |
Schering Corporation |
Compounds as inhibitors of hepatitis c virus ns3 serine protease
|
DE602005014621D1
(de)
|
2004-03-09 |
2009-07-09 |
Boehringer Ingelheim Pharma |
3-ä4-heterocyclyl-1,2,3-triazol-1-ylü-n-arylbenzamide als inhibitoren der cytokinenproduktion für die behandlung von chronischen entzündlichen erkrankungen
|
WO2005099824A1
(en)
|
2004-03-30 |
2005-10-27 |
Synta Pharmaceuticals, Corp. |
1-glyoxylamide indolizines for treating lung and ovarian cancer
|
JPWO2005102381A1
(ja)
|
2004-04-26 |
2008-03-06 |
小野薬品工業株式会社 |
カテプシンk阻害薬およびpth類を併用することを特徴とする骨密度増加剤
|
US7531560B2
(en)
|
2004-11-10 |
2009-05-12 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Anti-cytokine heterocyclic compounds
|
GB0426661D0
(en)
|
2004-12-06 |
2005-01-05 |
Isis Innovation |
Pyrrolidine compounds
|
JP2008527031A
(ja)
|
2005-01-19 |
2008-07-24 |
バイオリポックス エービー |
炎症の治療に有用なピロロピリジン誘導体
|
GB0503054D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
WO2006091862A2
(en)
|
2005-02-24 |
2006-08-31 |
Kemia, Inc. |
Cytokine inhibitors and their use in therapy
|
JP2009503081A
(ja)
|
2005-08-04 |
2009-01-29 |
スミスクライン ビーチャム コーポレーション |
Hivインテグラーゼ阻害薬
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
RS51470B
(en)
|
2005-09-16 |
2011-04-30 |
Arrow Therapeutics Limited |
BIPHENYL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF HEPATITIS C
|
WO2007058990A2
(en)
|
2005-11-14 |
2007-05-24 |
Kemia, Inc. |
Therapy using cytokine inhibitors
|
SI2455382T1
(sl)
|
2005-12-13 |
2017-03-31 |
Incyte Holdings Corporation |
S heteroarilom substituirani pirolo(2,3b)piridini in pirolo(2,3-b)pirimidini kot zaviralci janus kinaze
|
CN101007798B
(zh)
|
2006-01-24 |
2011-01-26 |
中国人民解放军军事医学科学院毒物药物研究所 |
苯并间二氧杂环戊烯衍生物及其制备方法和医药用途
|
JP5441416B2
(ja)
|
2006-02-14 |
2014-03-12 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
二官能性ヒストンデアセチラーゼインヒビター
|
US8017612B2
(en)
|
2006-04-18 |
2011-09-13 |
Japan Tobacco Inc. |
Piperazine compound and use thereof as a HCV polymerase inhibitor
|
TW200815437A
(en)
|
2006-06-13 |
2008-04-01 |
Bayer Schering Pharma Ag |
Substituted aminopyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
TW200815438A
(en)
|
2006-06-13 |
2008-04-01 |
Bayer Schering Pharma Ag |
Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
KR101130380B1
(ko)
|
2006-06-13 |
2012-04-23 |
상하이 인스티튜트 오브 마테리아 메디카 차이니즈 아카데미 오브 싸이언시즈 |
헤테로시클릭 비뉴클레오시드 화합물, 그의 제조방법, 약학적 조성물 및 항바이러스성 약제로서의 용도
|
EP1867648A1
(en)
|
2006-06-13 |
2007-12-19 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them.
|
EP1870410A1
(en)
|
2006-06-13 |
2007-12-26 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
EP1867647A1
(en)
|
2006-06-13 |
2007-12-19 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them.
|
JP5356228B2
(ja)
|
2006-07-07 |
2013-12-04 |
ギリアード サイエンシーズ, インコーポレイテッド |
toll様レセプター7の調節因子
|
US8158810B2
(en)
|
2006-07-27 |
2012-04-17 |
Gilead Sciences, Inc. |
ALDH-2 inhibitors in the treatment of addiction
|
EP1900739A1
(en)
|
2006-08-30 |
2008-03-19 |
Cellzome Ag |
Diazolodiazine derivatives as kinase inhibitors
|
TW200833690A
(en)
|
2006-12-15 |
2008-08-16 |
Bayer Schering Pharma Ag |
3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
EP1932845A1
(en)
|
2006-12-15 |
2008-06-18 |
Bayer Schering Pharma Aktiengesellschaft |
3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
WO2008091681A2
(en)
|
2007-01-23 |
2008-07-31 |
Housey Gerard M |
Theramutein modulators
|
DK2134689T3
(da)
|
2007-03-16 |
2014-06-30 |
Scripps Research Inst |
Inhibitorer af fokal adhæsionskinase
|
WO2008119792A1
(en)
|
2007-04-02 |
2008-10-09 |
Palau Pharma, S. A. |
Pyrrolopyrimidine derivatives as jak3 inhibitors
|
EA200901157A1
(ru)
|
2007-04-10 |
2010-04-30 |
ЭсДжиИкс ФАРМАСЬЮТИКАЛЗ, ИНК. |
Конденсированные кольцевые гетероциклические модуляторы киназы
|
EA021463B1
(ru)
|
2007-06-29 |
2015-06-30 |
Джилид Сайэнс, Инк. |
Пуриновые производные и их применение в качестве модуляторов толл-подобного рецептора 7
|
CN101754962B
(zh)
|
2007-07-19 |
2013-12-25 |
赛马拜制药公司 |
作为rup3或gpr119受体的激动剂治疗糖尿病和代谢性病症的n-氮杂环状经取代吡咯、吡唑、咪唑、三唑和四唑衍生物
|
EP2188272B1
(en)
|
2007-08-06 |
2016-02-24 |
reMynd NV |
Phenyl- and benzylthiazolylpiperazine derivatives for the treatment of neurodegenerative diseases
|
WO2009034433A2
(en)
|
2007-09-10 |
2009-03-19 |
Glenmark Pharmaceuticals, S.A. |
3-azabicyclo [3.1.0] hexane derivatives as vanilloid receptor ligands
|
WO2009033281A1
(en)
|
2007-09-14 |
2009-03-19 |
Methylgene Inc. |
Cancer combination therapy with a selective inhibitor of histone deacetylase hdac1, hdac2 and/or hdac3 and a microtubule stabilizer
|
AU2008316895A1
(en)
|
2007-10-22 |
2009-04-30 |
Memory Pharmaceuticals Corporation |
(1,4-diaza-bicyclo[3.2.2]non-6-en-4-yl)-heterocyclyl-methanone ligands for nicotinic acetylcholine receptors, useful for the treatment of disease
|
EP2070929A1
(en)
|
2007-12-11 |
2009-06-17 |
Bayer Schering Pharma Aktiengesellschaft |
Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
RU2544856C2
(ru)
|
2008-01-25 |
2015-03-20 |
Сергей Олегович Бачурин |
НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
WO2009105782A1
(en)
|
2008-02-21 |
2009-08-27 |
Sequoia Pharmaceuticals, Inc. |
Hiv protease inhibitor and cytochrome p450 inhibitor combinations
|
TW201000107A
(en)
|
2008-04-09 |
2010-01-01 |
Infinity Pharmaceuticals Inc |
Inhibitors of fatty acid amide hydrolase
|
WO2009133834A1
(ja)
|
2008-04-28 |
2009-11-05 |
塩野義製薬株式会社 |
血管内皮リパーゼ阻害活性を有するケトアミド誘導体
|
US20090298834A1
(en)
|
2008-06-02 |
2009-12-03 |
Hassan Pajouhesh |
4-(aminomethyl)cyclohexanamine derivatives as calcium channel blockers
|
US20090326019A1
(en)
|
2008-06-11 |
2009-12-31 |
Yat Sun Or |
3,4-bicyclic pyrrolidine antivirals
|
CN102203074A
(zh)
|
2008-06-20 |
2011-09-28 |
麦它波莱克斯股份有限公司 |
芳基gpr119激动剂及其用途
|
KR101927291B1
(ko)
|
2008-07-08 |
2018-12-10 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸
|
DK177227B1
(da)
|
2008-07-10 |
2012-07-23 |
Si Holding Aulum Aps |
Proces til kantbehandling på emner fremstillet af MDF materiale
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
FR2934593B1
(fr)
|
2008-07-29 |
2010-09-10 |
Pf Medicament |
Derives dimeriques d'artemisinine et application en therapie anticancereuse
|
ES2438496T3
(es)
|
2008-08-01 |
2014-01-17 |
Ventirx Pharmaceuticals, Inc. |
Formulaciones de agonistas de receptores de tipo toll y su uso
|
CA2734651A1
(en)
|
2008-08-21 |
2010-02-25 |
Richter Gedeon Nyrt. |
Methods for treating neuropathic pain
|
CA2736970A1
(en)
|
2008-09-12 |
2010-03-18 |
Biolipox Ab |
Pyrimidinone derivatives for use as medicaments
|
WO2010034740A1
(en)
|
2008-09-23 |
2010-04-01 |
Palau Pharma, S.A. |
(r)-3-(n,n-dimethylamino)pyrrolidine derivatives
|
CA2740885C
(en)
|
2008-10-16 |
2018-04-03 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
WO2010053998A1
(en)
|
2008-11-05 |
2010-05-14 |
Xenon Pharmaceuticals, Inc. |
Spiro-condensed indole derivatives as sodium channel inhibitors
|
PE20120106A1
(es)
|
2008-12-09 |
2012-02-20 |
Gilead Sciences Inc |
Moduladores de receptores tipo toll
|
US20110237633A1
(en)
|
2008-12-11 |
2011-09-29 |
Bijoy Panicker |
Small molecule modulators of hepatocyte growth factor (scatter factor) activity
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
TW201035102A
(en)
|
2009-03-04 |
2010-10-01 |
Gruenethal Gmbh |
Sulfonylated tetrahydroazolopyrazines and their use as medicinal products
|
JP5591318B2
(ja)
|
2009-04-02 |
2014-09-17 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
オートタキシン阻害剤としてのピペリジンおよびピペラジン誘導体
|
US8329907B2
(en)
|
2009-04-02 |
2012-12-11 |
Merck Patent Gmbh |
Autotaxin inhibitors
|
US9346809B2
(en)
|
2009-07-08 |
2016-05-24 |
Leo Pharma A/S |
Heterocyclic compounds as JAK receptor and protein tyrosine kinase inhibitors
|
DK2467380T3
(en)
|
2009-08-18 |
2017-03-13 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS
|
RU2016125705A
(ru)
|
2009-08-18 |
2018-12-04 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов тoll-подобных рецепторов
|
SG179194A1
(en)
|
2009-09-21 |
2012-05-30 |
Gilead Sciences Inc |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
WO2011048611A1
(en)
|
2009-10-07 |
2011-04-28 |
Torrent Pharmaceuticals Limited |
Novel fused pyridazine derivatives
|
PL2491035T3
(pl)
|
2009-10-22 |
2018-01-31 |
Gilead Sciences Inc |
Pochodne puryny lub deazapuryny przydatne do leczenia (między innymi) infekcji wirusowych
|
MX2012007662A
(es)
|
2010-01-07 |
2012-08-23 |
Polymedix Inc |
Compuestos anti-heparina.
|
WO2011087051A1
(ja)
|
2010-01-14 |
2011-07-21 |
国立大学法人金沢大学 |
S1p2受容体アンタゴニストを含む粥状動脈硬化治療薬
|
WO2011106573A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
ES2572387T3
(es)
|
2010-03-18 |
2016-05-31 |
Pasteur Institut Korea |
Compuestos anti-infecciosos
|
US8871799B2
(en)
|
2010-04-23 |
2014-10-28 |
Kineta, Inc. |
Iminochromene anti-viral compounds
|
US8927561B2
(en)
|
2010-04-23 |
2015-01-06 |
Kineta, Inc. |
Pyrimidinedione anti-viral compounds
|
AR081039A1
(es)
|
2010-05-14 |
2012-05-30 |
Osi Pharmaceuticals Llc |
Inhibidores biciclicos fusionados de quinasa
|
WO2011146401A1
(en)
|
2010-05-17 |
2011-11-24 |
Intermune, Inc. |
Novel inhibitors of hepatitis c virus replication
|
WO2011145669A1
(ja)
|
2010-05-19 |
2011-11-24 |
大日本住友製薬株式会社 |
アミド誘導体
|
ES2592152T3
(es)
|
2010-05-31 |
2016-11-28 |
Ono Pharmaceutical Co., Ltd. |
Derivado de purinona como inhibidor de Btk quinasa
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
WO2012016186A1
(en)
|
2010-07-29 |
2012-02-02 |
President And Fellows Of Harvard College |
Macrocyclic kinase inhibitors and uses thereof
|
JP2013537533A
(ja)
|
2010-07-30 |
2013-10-03 |
ランバクシー ラボラトリーズ リミテッド |
マトリックスメタロプロテイナーゼ阻害剤
|
US8999974B2
(en)
|
2010-08-09 |
2015-04-07 |
Raqualia Pharma Inc. |
Acyl piperazine derivatives as TTX-S blockers
|
US8859775B2
(en)
|
2010-09-02 |
2014-10-14 |
Merck Patent Gmbh |
Pyrazolopyridinone derivatives as LPA receptor antagonists
|
US20140148459A1
(en)
|
2010-09-24 |
2014-05-29 |
Ranbaxy Laboratories Limited |
Matrix metalloproteinase inhibitors
|
WO2012050868A1
(en)
|
2010-09-28 |
2012-04-19 |
Georgia Tech Research Corporation |
Histone deacetylase (hdac) inhibitors targeting prostate tumors and methods of making and using thereof
|
WO2012045090A2
(en)
|
2010-10-01 |
2012-04-05 |
Ventirx Pharmaceuticals, Inc. |
Therapeutic use of a tlr agonist and combination therapy
|
CA2812787A1
(en)
|
2010-10-01 |
2012-04-05 |
Robert Hershberg |
Methods for the treatment of allergic diseases
|
US9273028B2
(en)
|
2010-10-29 |
2016-03-01 |
Biogen Ma Inc. |
Heterocyclic tyrosine kinase inhibitors
|
UY33775A
(es)
|
2010-12-10 |
2012-07-31 |
Gilead Sciences Inc |
Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
|
TWI574687B
(zh)
|
2011-01-03 |
2017-03-21 |
古利斯股份有限公司 |
具有鋅結合部份之刺蝟拮抗劑
|
PL2663555T4
(pl)
|
2011-01-12 |
2017-08-31 |
Ventirx Pharmaceuticals, Inc. |
Podstawione benzoazepiny jako modulatory receptora toll-podobnego
|
DK2663550T3
(en)
|
2011-01-12 |
2017-03-27 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
US20120184572A1
(en)
|
2011-01-13 |
2012-07-19 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
AP2013007110A0
(en)
|
2011-02-12 |
2013-09-30 |
Globeimmune Inc |
Yeast-based therapeutic for chronic hepatitis B infection
|
CA2827311A1
(en)
|
2011-02-18 |
2012-08-23 |
Vertex Pharmaceuticals Incorporated |
Chroman-spirocyclic piperidine amides as modulators of ion channels
|
CA2827392A1
(en)
|
2011-02-24 |
2012-08-30 |
Emory University |
Noggin blocking compositions for ossification and methods related thereto
|
EP2685976B1
(en)
|
2011-03-17 |
2017-12-27 |
Tel HaShomer Medical Research Infrastructure and Services Ltd. |
Quinolone analogs for treating autoimmune diseases
|
US9464065B2
(en)
|
2011-03-24 |
2016-10-11 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
CA2832685C
(en)
|
2011-04-08 |
2020-09-01 |
Janssen R&D Ireland |
Pyrimidine derivatives for the treatment of viral infections
|
DK2709619T3
(en)
|
2011-05-16 |
2018-01-15 |
Cellceutix Corp |
RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS
|
JP6130827B2
(ja)
|
2011-05-17 |
2017-05-17 |
塩野義製薬株式会社 |
ヘテロ環化合物
|
NO2709989T3
(pl)
|
2011-05-18 |
2018-05-19 |
|
|
EP3199537B1
(en)
|
2011-05-19 |
2018-10-17 |
Gilead Sciences, Inc. |
Processes and intermediates for preparing anti-hiv agents
|
RU2013157374A
(ru)
|
2011-06-07 |
2015-07-20 |
Сумитомо Дайниппон Фарма Ко., Лтд. |
Производное индазола и пирролопиридина и его фармацевтическое применение
|
WO2012168944A1
(en)
|
2011-06-08 |
2012-12-13 |
Aurigene Discovery Technologies Limited |
Therapeutic compounds for immunomodulation
|
EP3085368A1
(en)
|
2011-07-01 |
2016-10-26 |
Baruch S. Blumberg Institute |
Sulfamoylbenzamide derivatives as antiviral agents against hbv infection
|
EP2737554B1
(de)
|
2011-07-29 |
2017-01-11 |
Merck Patent GmbH |
Verbindungen für elektronische vorrichtungen
|
DE102011080362A1
(de)
|
2011-08-03 |
2013-02-07 |
Robert Bosch Gmbh |
Elektrisches Kontaktelement mit Rastlanze für ein Steckergehäuse
|
JP2014527981A
(ja)
|
2011-09-23 |
2014-10-23 |
アドヴィナス・セラピューティックス・リミテッド |
アミド化合物、組成物およびその用途
|
WO2013059278A2
(en)
|
2011-10-17 |
2013-04-25 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
WO2013081016A1
(ja)
|
2011-11-29 |
2013-06-06 |
小野薬品工業株式会社 |
プリノン誘導体塩酸塩
|
US20140288145A1
(en)
|
2011-12-05 |
2014-09-25 |
Brandeis University |
Treatment of amyloidosis by compounds that regulate retromer stabilization
|
DE102011121022A1
(de)
|
2011-12-13 |
2013-06-13 |
Merck Patent Gmbh |
Organische Sensibilisatoren für Up- Conversion
|
BR112014015197A2
(pt)
|
2011-12-21 |
2017-06-13 |
Novira Therapeutics Inc |
agentes antivirais de hepatite b
|
TWI573792B
(zh)
|
2012-02-01 |
2017-03-11 |
歐陸斯迪公司 |
新穎治療劑
|
JP6283320B2
(ja)
|
2012-02-08 |
2018-02-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのピペリジノ−ピリミジン誘導体
|
CN104159911A
(zh)
|
2012-03-07 |
2014-11-19 |
奥瑞基尼探索技术有限公司 |
作为免疫调节剂的模拟肽化合物
|
EP2831108A1
(en)
|
2012-03-29 |
2015-02-04 |
Aurigene Discovery Technologies Limited |
Immunomodulating cyclic compounds from the bc loop of human pd1
|
WO2013144228A1
(en)
|
2012-03-29 |
2013-10-03 |
Basf Se |
Pesticidal methods using heterocyclic compounds and derivatives for combating animal pests
|
RU2014142598A
(ru)
|
2012-03-31 |
2016-05-27 |
Ф. Хоффманн-Ля Рош Аг |
Новые 4-метилдигидропиримидины для лечения и профилактики инфекции вируса гепатита в
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2013161871A1
(ja)
|
2012-04-25 |
2013-10-31 |
興和株式会社 |
Tlr阻害作用を有するチオフェン誘導体
|
BR112014030649A2
(pt)
|
2012-06-08 |
2017-06-27 |
Gilead Sciences Inc |
inibidores macrocíclicos da flaviviridae vírus
|
AR091279A1
(es)
|
2012-06-08 |
2015-01-21 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
KR20150040265A
(ko)
|
2012-06-08 |
2015-04-14 |
길리애드 사이언시즈, 인코포레이티드 |
플라비비리대 바이러스의 마크로시클릭 저해제
|
MY183534A
(en)
|
2012-08-10 |
2021-02-25 |
Janssen Sciences Ireland Uc |
Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
|
WO2014031872A2
(en)
|
2012-08-23 |
2014-02-27 |
The Broad Institute, Inc. |
Small molecule inhibitors for treating parasitic infections
|
TWI696606B
(zh)
|
2012-08-28 |
2020-06-21 |
愛爾蘭商健生科學愛爾蘭無限公司 |
胺磺醯基-芳醯胺類及其做為治療b型肝炎之醫藥劑的用途
|
PL2890683T3
(pl)
|
2012-08-28 |
2017-06-30 |
Janssen Sciences Ireland Uc |
Pochodne skondensowanego bicyklicznego sulfamylu i ich zastosowanie jako leki do leczenia wirusowego zapalenia wątroby typu B
|
EP2892899B1
(en)
|
2012-09-06 |
2018-03-21 |
Bristol-Myers Squibb Company |
Imidazopyridazine jak3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
|
WO2014037480A1
(en)
|
2012-09-10 |
2014-03-13 |
F. Hoffmann-La Roche Ag |
6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
IN2015DN02008A
(pl)
|
2012-09-21 |
2015-08-14 |
Advinus Therapeutics Ltd |
|
EP3150582A1
(en)
|
2012-10-02 |
2017-04-05 |
Gilead Sciences, Inc. |
Inhibitors of histone demethylases
|
KR102280595B1
(ko)
|
2012-10-10 |
2021-07-22 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 및 다른 질환 치료를 위한 피롤로[3,2-d]피리미딘 유도체
|
KR101268466B1
(ko)
|
2012-11-12 |
2013-06-04 |
유병수 |
사축형 윈드 터빈
|
CN105051018B
(zh)
|
2012-11-16 |
2019-09-20 |
爱尔兰詹森科学公司 |
用于治疗病毒性感染的杂环的经取代的2-氨基-喹唑啉衍生物
|
EP3763367A1
(en)
|
2012-12-06 |
2021-01-13 |
Celgene Quanticel Research, Inc. |
Pyridine-pyrazole derivatives as histone demethylase inhibitors
|
CN110642741A
(zh)
|
2012-12-06 |
2020-01-03 |
巴鲁克斯布隆伯格研究所 |
作为抗hbv感染的抗病毒剂的官能化苯甲酰胺衍生物
|
JP2014133739A
(ja)
|
2012-12-12 |
2014-07-24 |
Dainippon Sumitomo Pharma Co Ltd |
インダゾール誘導体またはピロロピリジン誘導体からなる医薬
|
PL2934145T3
(pl)
|
2012-12-19 |
2018-04-30 |
Celgene Quanticel Research, Inc. |
Inhibitory demetylazy histonowej
|
MX2015007997A
(es)
|
2012-12-21 |
2016-02-18 |
Quanticel Pharmaceuticals Inc |
Inhibidores de histona desmetilasa.
|
WO2014096965A2
(en)
|
2012-12-21 |
2014-06-26 |
Rvx Therapeutics Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
ES2660288T3
(es)
|
2012-12-24 |
2018-03-21 |
Cadila Healthcare Limited |
Derivados de quinolona
|
CA2896554C
(en)
|
2012-12-27 |
2019-11-05 |
Drexel University |
Novel antiviral agents against hbv infection
|
JP6346904B2
(ja)
|
2013-01-10 |
2018-06-20 |
ベナトルクス ファーマシューティカルズ,インク. |
ベータ−ラクタマーゼ阻害剤
|
HUE033962T2
(en)
|
2013-01-29 |
2018-01-29 |
Redx Pharma Plc |
Pyridine derivatives as soft rock (RHO kinase) inhibitors
|
GB201303109D0
(en)
|
2013-02-21 |
2013-04-10 |
Domainex Ltd |
Novel pyrimidine compounds
|
DK2958900T3
(da)
|
2013-02-21 |
2019-07-01 |
Janssen Sciences Ireland Unlimited Co |
2-aminopyrimidinderivater til behandling af virusinfektioner
|
SI2961736T1
(en)
|
2013-02-27 |
2018-06-29 |
Gilead Sciences, Inc. |
Histone demethylase inhibitors
|
CA2899706C
(en)
|
2013-02-28 |
2021-10-19 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
US9738637B2
(en)
|
2013-03-12 |
2017-08-22 |
Celgene Quantical Research, Inc. |
Histone demethylase inhibitors
|
WO2014165128A2
(en)
|
2013-03-12 |
2014-10-09 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
EP2970307B1
(en)
|
2013-03-13 |
2020-03-11 |
Genentech, Inc. |
Pyrazolo compounds and uses thereof
|
AU2014236711A1
(en)
|
2013-03-14 |
2015-09-17 |
Celgene Quanticel Research, Inc. |
Histone demethylase inhibitors
|
EP2970340B1
(en)
|
2013-03-14 |
2020-02-12 |
Venatorx Pharmaceuticals, Inc. |
Beta-lactamase inhibitors
|
SI2970211T1
(sl)
|
2013-03-15 |
2017-12-29 |
Quanticel Pharmaceuticals Inc. |
Inhibitorji histon demetilaze
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
DK2981536T3
(en)
*
|
2013-04-03 |
2017-09-25 |
Janssen Sciences Ireland Uc |
N-PHENYLC CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR THE TREATMENT OF HEPATITIS B
|
WO2014179144A1
(en)
|
2013-04-29 |
2014-11-06 |
E. I. Du Pont De Nemours And Company |
Fungicidal heterocyclic compounds
|
WO2014179760A1
(en)
|
2013-05-03 |
2014-11-06 |
The Regents Of The University Of California |
Cyclic di-nucleotide induction of type i interferon
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
EA201592126A1
(ru)
|
2013-05-17 |
2016-05-31 |
Ф. Хоффманн-Ля Рош Аг |
6-мостиковые гетероарилдигидропиримидины для лечения и профилактики заражения вирусом гепатита b
|
SI2997019T1
(sl)
|
2013-05-17 |
2018-12-31 |
Janssen Sciences Ireland Uc, |
Derivati sulfamoiliofenamida in njihova uporaba kot zdravila za zdravljenje hepatitisa B
|
JP6380862B2
(ja)
|
2013-06-28 |
2018-08-29 |
ベイジーン リミテッド |
複数種類のキナーゼの阻害剤としての縮合三環式アミド系化合物
|
EP3016953A4
(en)
|
2013-07-02 |
2017-03-01 |
Pharmacyclics, LLC |
Purinone compounds as kinase inhibitors
|
KR102244937B1
(ko)
*
|
2013-07-25 |
2021-04-27 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
글리옥사미드 치환된 피롤아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
EA036162B1
(ru)
|
2013-07-30 |
2020-10-08 |
Янссен Сайенсиз Айрлэнд Юси |
Производные тиено[3,2-d]пиримидинов для лечения вирусных инфекций
|
CA2920377A1
(en)
|
2013-08-05 |
2015-02-12 |
Cambridge Enterprise Limited |
Inhibition of cxcr4 signaling in cancer immunotherapy
|
WO2015023958A1
(en)
|
2013-08-15 |
2015-02-19 |
The University Of Kansas |
Toll-like receptor agonists
|
EP3035924A4
(en)
|
2013-08-20 |
2017-04-19 |
City of Hope |
Hdac8 inhibitors for treating cancer
|
KR101715090B1
(ko)
|
2013-08-28 |
2017-03-13 |
한국화학연구원 |
신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물
|
JP6417419B2
(ja)
|
2013-09-04 |
2018-11-07 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
免疫調節剤として有用な化合物
|
MY186438A
(en)
|
2013-09-06 |
2021-07-22 |
Aurigene Discovery Tech Ltd |
1, 2, 4-oxadiazole derivatives as immunomodulators
|
US20160194295A1
(en)
|
2013-09-06 |
2016-07-07 |
Aurigene Discovery Technologies Limited |
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives as Immunomodulators
|
HUE039012T2
(hu)
|
2013-09-06 |
2018-12-28 |
Aurigene Discovery Tech Ltd |
Gyûrûs peptidomimetikus vegyületek, mint immunomodulátorok
|
WO2015036927A1
(en)
|
2013-09-10 |
2015-03-19 |
Aurigene Discovery Technologies Limited |
Immunomodulating peptidomimetic derivatives
|
PL3043865T3
(pl)
|
2013-09-11 |
2021-07-05 |
Institut National De La Santé Et De La Recherche Médicale (Inserm) |
SPOSOBY I KOMPOZYCjE FARMACEUTYCZNE W LECZENIU ZAKAŻENIA WIRUSEM ZAPALENIA WĄTROBY TYPU B
|
WO2015044900A1
(en)
|
2013-09-27 |
2015-04-02 |
Aurigene Discovery Technologies Limited |
Therapeutic immunomodulating compounds
|
WO2015051230A1
(en)
|
2013-10-04 |
2015-04-09 |
Drexel University |
Novel compositions useful for inhibiting hiv-1 infection and methods using same
|
RU2671496C2
(ru)
|
2013-10-14 |
2018-11-01 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Производные 5-пиперидин-8-цианохинолина
|
EP3995495A1
(en)
|
2013-10-14 |
2022-05-11 |
Eisai R&D Management Co., Ltd. |
Selectively substituted quinoline compounds
|
WO2015058140A1
(en)
|
2013-10-18 |
2015-04-23 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)
|
WO2015057945A1
(en)
|
2013-10-18 |
2015-04-23 |
Indiana University Research And Technology Corporation |
Hepatitis b viral assembly effectors
|
EP3060547B1
(en)
|
2013-10-23 |
2017-10-11 |
Janssen Sciences Ireland UC |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
WO2015073774A1
(en)
|
2013-11-14 |
2015-05-21 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis b infections
|
WO2015085238A1
(en)
|
2013-12-05 |
2015-06-11 |
The Regents Of The University Of California, A California Corporation |
Inhibitors of lpxc
|
CA2933466A1
(en)
|
2013-12-13 |
2015-06-18 |
Takeda Pharmaceutical Company Limited |
Pyrrolo[3,2-c]pyridine derivatives as tlr inhibitors
|
WO2015095780A1
(en)
|
2013-12-20 |
2015-06-25 |
The University Of Kansas |
Toll-like receptor 8 agonists
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
JP2017504633A
(ja)
|
2014-01-30 |
2017-02-09 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染の治療及び予防のための新規なジヒドロキノリジノン
|
BR112016017700A2
(pt)
|
2014-02-04 |
2017-10-10 |
Incyte Corp |
método para tratamento de um câncer em um indivíduo, medicamento, kit, método, uso ou kit, e, método, medicamento ou kit
|
AU2015214096B2
(en)
|
2014-02-05 |
2021-02-11 |
Novira Therapeutics, Inc. |
Combination therapy for treatment of HBV infections
|
JP6495929B2
(ja)
|
2014-02-06 |
2019-04-03 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
スルファモイルピロールアミド誘導体およびb型肝炎の治療のための医薬としてのその使用
|
US20170088626A1
(en)
|
2014-03-05 |
2017-03-30 |
Bristol-Myers Squibb Company |
Treatment of renal cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
LT3114128T
(lt)
|
2014-03-07 |
2019-03-25 |
F. Hoffmann-La Roche Ag |
Nauji 6 padėtyje kondensuoti heteroarildihidropirimidinai, skirti hepatito b virusinės infekcijos gydymui ir profilaktikai
|
EP3122353B1
(en)
|
2014-03-27 |
2020-10-28 |
Vanderbilt University |
Substituted indole mcl-1 inhibitors
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
US9850225B2
(en)
|
2014-04-14 |
2017-12-26 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
BR112016017261B1
(pt)
|
2014-04-22 |
2022-04-19 |
F. Hoffmann-La Roche Ag |
Composto, composição farmacêutica, uso de um composto e processo para a fabricação de um composto
|
PE20170325A1
(es)
|
2014-05-01 |
2017-04-21 |
Novartis Ag |
Compuestos y composiciones como agonistas del receptor tipo toll
|
CA2945504A1
(en)
|
2014-05-01 |
2015-11-05 |
Novartis Ag |
Compounds and compositions as toll-like receptor 7 agonists
|
KR20160148715A
(ko)
|
2014-05-13 |
2016-12-26 |
에프. 호프만-라 로슈 아게 |
B형 간염 바이러스 감염의 치료 또는 예방을 위한 신규한 다이하이드로퀴놀리진온
|
CA2949961C
(en)
|
2014-05-23 |
2023-09-19 |
Eisai R&D Management Co., Ltd. |
Combination therapies for the treatment of cancer
|
AU2015266481B2
(en)
|
2014-05-30 |
2018-06-07 |
Qilu Pharmaceuticals Co., Ltd. |
Dihydropyrimido fused ring derivative as HBV inhibitor
|
WO2015188085A1
(en)
|
2014-06-06 |
2015-12-10 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
BR112017000714A2
(pt)
|
2014-07-16 |
2018-01-09 |
Novogen ltd |
indols funcionalizados e substituídos como agentes anti-câncer
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
SG11201700700YA
(en)
|
2014-08-01 |
2017-02-27 |
3M Innovative Properties Co |
Methods and therapeutic combinations for treating tumors
|
MX2017001862A
(es)
|
2014-08-14 |
2017-05-15 |
Hoffmann La Roche |
Nuevas piridazonas y triazinonas para el tratamiento y la profilaxis de infeccion por virus de hepatitis b.
|
SG11201701169XA
(en)
|
2014-08-15 |
2017-03-30 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
Pyrrolopyrimidine compounds used as tlr7 agonist
|
JP2017525711A
(ja)
|
2014-08-22 |
2017-09-07 |
ジャナス バイオセラピューティクス,インク. |
新規なn2,n4,n7,6−四置換プテリジン−2,4,7−トリアミンおよび2,4,6,7−四置換プテリジン化合物ならびにその合成方法および使用
|
AU2015306662A1
(en)
|
2014-08-27 |
2017-03-09 |
Gilead Sciences, Inc. |
Compounds and methods for inhibiting histone demethylases
|
US9884866B2
(en)
|
2014-09-08 |
2018-02-06 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
AU2014405919B2
(en)
|
2014-09-11 |
2020-02-20 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80 (B7-1)/PD-Li protein/protein interactions
|
EP3204379B1
(en)
|
2014-10-10 |
2019-03-06 |
Genentech, Inc. |
Pyrrolidine amide compounds as histone demethylase inhibitors
|
US9732119B2
(en)
|
2014-10-10 |
2017-08-15 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EP3204392A1
(en)
|
2014-10-11 |
2017-08-16 |
F. Hoffmann-La Roche AG |
Compounds for use in the treatment of infectious diseases
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
BE1023340B1
(fr)
|
2014-11-13 |
2017-02-08 |
Glaxosmithkline Biologicals S.A. |
Composes
|
US9856292B2
(en)
|
2014-11-14 |
2018-01-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
BR112017011941B1
(pt)
|
2014-12-08 |
2023-02-28 |
F. Hoffmann-La Roche Ag |
Compostos 5-amino-6h-tiazol [4,5-d] pirimidina-2,7-diona 3-substituídos para o tratamento e profilaxia de infecção viral
|
US9861680B2
(en)
|
2014-12-18 |
2018-01-09 |
Bristol-Myers Squibb Company |
Immunomodulators
|
CN107148417B
(zh)
|
2014-12-18 |
2020-09-08 |
豪夫迈·罗氏有限公司 |
苯并氮杂*磺酰胺化合物
|
US9944678B2
(en)
|
2014-12-19 |
2018-04-17 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2016102438A1
(en)
|
2014-12-23 |
2016-06-30 |
F. Hoffmann-La Roche Ag |
Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidine analogues
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
Hoffmann-Laroche Inc. |
Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
CN105732635A
(zh)
|
2014-12-29 |
2016-07-06 |
南京明德新药研发股份有限公司 |
一类Toll样受体7激动剂
|
EP3240537B1
(en)
|
2014-12-30 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
US9550779B2
(en)
|
2014-12-30 |
2017-01-24 |
Novira Therapeutics, Inc. |
Derivatives and methods of treating hepatitis B infections
|
JP2018504891A
(ja)
|
2014-12-31 |
2018-02-22 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
リアルタイムPCRによる細胞溶解物からのHBV cccDNA定量化のための新規ハイスループット法
|
EP3242878B1
(en)
|
2015-01-08 |
2020-10-14 |
Impetis Biosciences Ltd. |
Bicyclic compounds, compositions and medicinal applications thereof
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
WO2016120186A1
(en)
|
2015-01-27 |
2016-08-04 |
F. Hoffmann-La Roche Ag |
Recombinant hbv cccdna, the method to generate thereof and the use thereof
|
EP3256471B1
(en)
|
2015-02-11 |
2018-12-12 |
F. Hoffmann-La Roche AG |
Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
|
WO2016128908A1
(en)
|
2015-02-12 |
2016-08-18 |
Advinus Therapeutics Limited |
Bicyclic compounds, compositions and medicinal applications thereof
|
US9670205B2
(en)
|
2015-03-04 |
2017-06-06 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
SI3265458T1
(sl)
|
2015-03-06 |
2019-03-29 |
F. Hoffmann-La Roche Ag |
Benzazepin dikarboksamidne spojine
|
BR112017019304A2
(pt)
|
2015-03-10 |
2018-05-08 |
Aurigene Discovery Technologies Limited |
compostos de 1,2,4-oxadiazol 3-substituído e tiadiazol como imunomoduladores
|
EP3267993A4
(en)
|
2015-03-10 |
2018-08-08 |
Aurigene Discovery Technologies Limited |
Therapeutic cyclic compounds as immunomodulators
|
EP3267999A4
(en)
|
2015-03-10 |
2018-07-25 |
Aurigene Discovery Technologies Limited |
1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
|
CA2979137C
(en)
|
2015-03-10 |
2023-12-19 |
Aurigene Discovery Technologies Limited |
1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
|
CU20170117A7
(es)
|
2015-03-10 |
2018-05-08 |
Aurigene Discovery Tech Ltd |
COMPUESTOS TIADIAZOL y 1,3,4-OXADIAZOL 3-SUSTITUIDOS COMO INMUNOMODULADORES
|
US9809625B2
(en)
|
2015-03-18 |
2017-11-07 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US10442788B2
(en)
|
2015-04-01 |
2019-10-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
US10273228B2
(en)
|
2015-04-17 |
2019-04-30 |
Indiana University Research And Technology Corporation |
Hepatitis B viral assembly effectors
|
EP3292120B1
(en)
|
2015-05-04 |
2019-06-19 |
H. Hoffnabb-La Roche Ag |
Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
|
WO2016180743A1
(en)
|
2015-05-12 |
2016-11-17 |
F. Hoffmann-La Roche Ag |
Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection
|
WO2016189129A1
(de)
|
2015-05-28 |
2016-12-01 |
Basf Se |
Verfahren zur homogen katalysierten reduktiven aminierung von carbonyl-verbindungen
|
WO2016195982A2
(en)
|
2015-06-01 |
2016-12-08 |
The Penn State Research Foundation |
Hepatitis b virus capsid assembly
|
WO2016201370A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
WO2016201440A1
(en)
|
2015-06-12 |
2016-12-15 |
The Regents Of The University Of California |
Spiroindolinones and therapeutic uses thereof
|
US20160376864A1
(en)
|
2015-06-29 |
2016-12-29 |
Cameron International Corporation |
Apparatus and method for distributing fluids to a wellbore
|
GB201511477D0
(en)
|
2015-06-30 |
2015-08-12 |
Redx Pharma Plc |
Antiviral compounds
|
WO2017001307A1
(en)
|
2015-06-30 |
2017-01-05 |
F. Hoffmann-La Roche Ag |
Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
WO2017007701A1
(en)
|
2015-07-07 |
2017-01-12 |
Merck Sharp & Dohme Corp. |
Antiviral phosphodiamide compounds
|
JP6732008B2
(ja)
|
2015-07-20 |
2020-07-29 |
浙江中科▲創▼越▲薬▼▲業▼有限公司 |
シュウ酸アミド系配位子および銅触媒によるハロゲン化アリールのカップリング反応におけるその使用
|
EP3325477B1
(en)
|
2015-07-21 |
2019-05-01 |
H. Hoffnabb-La Roche Ag |
Novel tricyclic 4-pyridone-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
|
WO2017015451A1
(en)
|
2015-07-22 |
2017-01-26 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
WO2017016960A1
(en)
|
2015-07-24 |
2017-02-02 |
F. Hoffmann-La Roche Ag |
Process for the preparation of (6s)-6-alkyl-10-alkoxy-9-(substituted alkoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid analogues
|
WO2017017042A1
(en)
|
2015-07-27 |
2017-02-02 |
F. Hoffmann-La Roche Ag |
Novel tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
|
CN107835813B
(zh)
|
2015-07-28 |
2020-04-24 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的6,7-二氢吡啶并[2,1-a]酞嗪-2-酮类化合物
|
AU2016298823A1
(en)
|
2015-07-29 |
2018-02-08 |
Novartis Ag |
Combination of PD-1 antagonist with an EGFR inhibitor
|
GB2537192B
(en)
*
|
2015-08-05 |
2017-04-12 |
Harkness Screens Int Ltd |
A projection screen
|
AU2016305941B2
(en)
|
2015-08-10 |
2018-11-15 |
Merck Sharp & Dohme Llc |
Antiviral beta-amino acid ester phosphodiamide compounds
|
KR102222186B1
(ko)
|
2015-08-13 |
2021-03-03 |
머크 샤프 앤드 돔 코포레이션 |
Sting 효능제로서 시클릭 디-뉴클레오티드 화합물
|
EP3337481B1
(en)
|
2015-08-21 |
2020-11-11 |
The University of Kansas |
Quinoline-2-amine derivatives as human tlr8-selective agonists for increasing immune response
|
WO2017038909A1
(en)
|
2015-08-28 |
2017-03-09 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compounds
|
CA2996213C
(en)
|
2015-08-31 |
2023-10-03 |
3M Innovative Properties Company |
Guanidine substituted imidazo[4,5-c] ring compounds
|
WO2017040963A1
(en)
|
2015-09-03 |
2017-03-09 |
Forma Therapeutics, Inc. |
[6,6] fused bicyclic hdac8 inhibitors
|
TWI721016B
(zh)
|
2015-09-15 |
2021-03-11 |
美商艾森伯利生物科學公司 |
B型肝炎核心蛋白質調節劑
|
WO2017047769A1
(ja)
|
2015-09-17 |
2017-03-23 |
国立大学法人富山大学 |
トール様受容体7またはトール様受容体9の活性化阻害剤
|
WO2017046112A1
(en)
|
2015-09-17 |
2017-03-23 |
F. Hoffmann-La Roche Ag |
Sulfinylphenyl or sulfonimidoylphenyl benzazepines
|
GB201516614D0
(en)
|
2015-09-18 |
2015-11-04 |
Redx Pharma Plc |
Antibacterial compounds
|
EP3360554B1
(en)
|
2015-10-05 |
2021-07-28 |
FUJIFILM Toyama Chemical Co., Ltd. |
Anti-hepatitis b virus agent
|
PL3868741T3
(pl)
|
2015-10-07 |
2024-01-29 |
Sumitomo Pharma Co., Ltd. |
Kompozycja zawierająca związek pirymidynowy i antygen pochodzący od patogenu
|
US10745382B2
(en)
|
2015-10-15 |
2020-08-18 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
ES2928164T3
(es)
|
2015-10-19 |
2022-11-15 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
TW201726700A
(zh)
|
2015-10-28 |
2017-08-01 |
艾杜諾生物科技公司 |
用於活化「干擾素基因刺激子」依賴性訊號之組合物及方法
|
CA3004083A1
(en)
|
2015-11-04 |
2017-05-11 |
Incyte Corporation |
Pharmaceutical compositions and methods for indoleamine 2,3-dioxygenase inhibition and indications therefor
|
KR102112192B1
(ko)
|
2015-11-05 |
2020-05-19 |
치아타이 티안큉 파마수티컬 그룹 주식회사 |
Tlr7 효능제로서의 7-(티아졸-5-일)피롤로피리미딘 화합물
|
CN113546052A
(zh)
|
2015-11-09 |
2021-10-26 |
吉利德科学公司 |
治疗人免疫缺陷病毒的治疗组合物
|
EP3377488B1
(en)
|
2015-11-19 |
2022-08-10 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
EA201891121A1
(ru)
|
2015-11-19 |
2018-12-28 |
Бристол-Майерс Сквибб Компани |
Антитела к глюкокортикоид-индуцированному рецептору фактора некроза опухоли (gitr) и их применения
|
AU2016362697B2
(en)
|
2015-12-03 |
2018-07-12 |
Glaxosmithkline Intellectual Property Development Limited |
Cyclic purine dinucleotides as modulators of STING
|
WO2017100108A1
(en)
|
2015-12-10 |
2017-06-15 |
Merck Sharp & Dohme Corp. |
Antiviral phosphodiamide prodrugs of tenofovir
|
WO2017106740A1
(en)
|
2015-12-16 |
2017-06-22 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"-dependent interferon production
|
JP6882299B2
(ja)
|
2015-12-17 |
2021-06-02 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
多環式tlr7/8アンタゴニスト及び免疫障害の治療におけるそれらの使用
|
TW201726623A
(zh)
|
2015-12-17 |
2017-08-01 |
英塞特公司 |
作為免疫調節劑之雜環化合物
|
KR20180100585A
(ko)
|
2015-12-22 |
2018-09-11 |
인사이트 코포레이션 |
면역조절제로서의 헤테로사이클릭 화합물
|
CN106928219B
(zh)
|
2015-12-31 |
2021-08-20 |
上海医药集团股份有限公司 |
含氮稠杂环化合物、制备方法、中间体、组合物和应用
|
ES2897913T3
(es)
|
2016-02-19 |
2022-03-03 |
Novartis Ag |
Compuestos de piridona tetracíclicos como antivirales
|
WO2017156255A1
(en)
*
|
2016-03-09 |
2017-09-14 |
Emory University |
Elimination of hepatitis b virus with antiviral agents
|
US10781218B2
(en)
|
2016-03-16 |
2020-09-22 |
Kura Oncology, Inc. |
Substituted inhibitors of menin-MLL and methods of use
|
HUE060396T2
(hu)
|
2016-03-18 |
2023-02-28 |
Immune Sensor Llc |
Ciklikus DI-nukleotid vegyületek és azok felhasználási módszerei
|
DK3433249T3
(da)
|
2016-03-21 |
2023-02-13 |
Council Scient Ind Res |
Blokering af toll-lignende receptor 9 signalering med en lille molekyleantagonist
|
CN107922366A
(zh)
|
2016-03-23 |
2018-04-17 |
华东理工大学 |
丙酮酸脱氢酶激酶抑制剂及其应用
|
CN107226805A
(zh)
|
2016-03-24 |
2017-10-03 |
北京天诚医药科技有限公司 |
芳香族酰胺类衍生物、其制备方法及其在医药上的应用
|
US10738030B2
(en)
|
2016-03-31 |
2020-08-11 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
US10358463B2
(en)
|
2016-04-05 |
2019-07-23 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2017184735A1
(en)
|
2016-04-19 |
2017-10-26 |
Ifm Therapeutics, Inc |
Nlrp3 modulators
|
EP3445761A1
(en)
|
2016-04-19 |
2019-02-27 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
EP3448393A1
(en)
|
2016-04-25 |
2019-03-06 |
Invivogen |
Novel complexes of immunostimulatory compounds, and uses thereof
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
WO2017192961A1
(en)
|
2016-05-06 |
2017-11-09 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
HUE057924T2
(hu)
|
2016-05-06 |
2022-06-28 |
Shanghai De Novo Pharmatech Co Ltd |
Benzazepin származék, elõállítási eljárása, gyógyászati készítmény és alkalmazása
|
EP3458455B1
(en)
|
2016-05-20 |
2021-06-16 |
F. Hoffmann-La Roche AG |
Novel pyrazine compounds with oxygen, sulfur and nitrogen linker for the treatment of infectious diseases
|
EP3464245B1
(en)
|
2016-05-23 |
2020-10-14 |
H. Hoffnabb-La Roche Ag |
Benzazepine dicarboxamide compounds with tertiary amide function
|
CN109311854B
(zh)
|
2016-05-23 |
2021-08-10 |
豪夫迈·罗氏有限公司 |
具有仲酰胺官能团的苯并氮杂卓二甲酰胺化合物
|
CN109311860B
(zh)
|
2016-05-26 |
2022-04-08 |
豪夫迈·罗氏有限公司 |
用于治疗或预防乙型肝炎病毒疾病的呫吨酮衍生物
|
MA45116A
(fr)
|
2016-05-26 |
2021-06-02 |
Incyte Corp |
Composés hétérocycliques comme immunomodulateurs
|
WO2017209265A1
(ja)
|
2016-06-03 |
2017-12-07 |
塩野義製薬株式会社 |
二環性複素環誘導体およびそれらを含有する医薬組成物
|
WO2017211791A1
(en)
|
2016-06-07 |
2017-12-14 |
F. Hoffmann-La Roche Ag |
Combination therapy of an hbsag inhibitor and a tlr7 agonist
|
EP3468561A4
(en)
|
2016-06-10 |
2019-12-04 |
Enanta Pharmaceuticals, Inc. |
ANTIVIRAL AGENTS AGAINST HEPATITIS B
|
WO2017216054A1
(en)
|
2016-06-12 |
2017-12-21 |
F. Hoffmann-La Roche Ag |
Dihydropyrimidinyl benzazepine carboxamide compounds
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
PE20190731A1
(es)
|
2016-06-20 |
2019-05-23 |
Incyte Corp |
Compuestos heterociclicos como inmunomoduladores
|
CN108290893B
(zh)
|
2016-06-22 |
2021-01-05 |
四川科伦博泰生物医药股份有限公司 |
二氢蝶啶酮类衍生物、其制备方法及其用途
|
ES2817426T3
(es)
|
2016-06-29 |
2021-04-07 |
Novira Therapeutics Inc |
Derivados de oxadiazepinona y su uso en el tratamiento de infecciones por hepatitis B
|
WO2018001952A1
(en)
|
2016-06-29 |
2018-01-04 |
F. Hoffmann-La Roche Ag |
Novel tetrahydropyridopyrimidines for the treatment and prophylaxis of hbv infection
|
US10071079B2
(en)
|
2016-06-29 |
2018-09-11 |
Bristol-Myers Squibb Company |
[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds
|
CN107537157B
(zh)
|
2016-06-29 |
2022-05-17 |
无敌媒体有限公司 |
用于减少具有虚拟货币的电子游戏中的欺诈的系统和方法
|
CN109415367B
(zh)
|
2016-06-29 |
2021-04-16 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的新的二氢吡咯并嘧啶类化合物
|
CN114057739A
(zh)
|
2016-06-29 |
2022-02-18 |
诺维拉治疗公司 |
二氮杂酮衍生物及其在治疗乙型肝炎感染中的用途
|
KR102468272B1
(ko)
|
2016-06-30 |
2022-11-18 |
삼성전자주식회사 |
음향 출력 장치 및 그 제어 방법
|
US11053256B2
(en)
|
2016-07-01 |
2021-07-06 |
Janssen Sciences Ireland Unlimited Company |
Dihydropyranopyrimidines for the treatment of viral infections
|
JP6301402B2
(ja)
|
2016-07-01 |
2018-03-28 |
日新製鋼株式会社 |
フェライト系ステンレス鋼板およびその製造方法
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
SG11201900077QA
(en)
|
2016-07-08 |
2019-02-27 |
Bristol Myers Squibb Co |
1,3-dihydroxy-phenyl derivatives useful as immunomodulators
|
JP7034133B2
(ja)
|
2016-07-14 |
2022-03-11 |
エフ.ホフマン-ラ ロシュ アーゲー |
感染性疾患の処置のためのカルボキシ 6,7-ジヒドロ-4H-ピラゾロ[1,5-a]ピラジン化合物
|
CN109476668B
(zh)
|
2016-07-14 |
2022-03-22 |
豪夫迈·罗氏有限公司 |
用于治疗感染性疾病的6,7-二氢-4H-吡唑并[1,5-a]吡嗪和6,7-二氢-4H-三唑并[1,5-a]吡嗪化合物
|
EP3484883B1
(en)
|
2016-07-14 |
2020-04-15 |
H. Hoffnabb-La Roche Ag |
Novel tetrahydropyrazolopyridine compounds for the treatment of infectious diseases
|
WO2018011160A1
(en)
|
2016-07-14 |
2018-01-18 |
F. Hoffmann-La Roche Ag |
6,7-dihydro-4h-pyrazolo[1,5-a]pyrazine compounds for the treatment of infectious diseases
|
ES2930092T3
(es)
|
2016-07-14 |
2022-12-07 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
WO2018019297A1
(zh)
|
2016-07-29 |
2018-02-01 |
银杏树药业(苏州)有限公司 |
异喹啉酮类化合物及其制备抗病毒药物的应用
|
EP3490987B1
(en)
|
2016-07-29 |
2022-09-21 |
Guangzhou Lupeng Pharmaceutical Company Ltd. |
Novel therapeutic agents for the treatment of hbv infection
|
WO2018026620A1
(en)
|
2016-07-30 |
2018-02-08 |
Bristol-Myers Squibb Company |
Dimethoxyphenyl substituted indole compounds as tlr7, tlr8 or tlr9 inhibitors
|
WO2018026971A1
(en)
|
2016-08-03 |
2018-02-08 |
Arising International, Llc |
Symmetric or semi-symmetric compounds useful as immunomodulators
|
CN109689059A
(zh)
|
2016-08-24 |
2019-04-26 |
豪夫迈·罗氏有限公司 |
Hbv衣壳组装抑制剂和核苷或核苷酸类似物的组合疗法
|
JOP20190024A1
(ar)
*
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
EP3889158B1
(en)
|
2016-08-26 |
2024-07-03 |
Solventum Intellectual Properties Company |
Fused [1,2]imidazo[4,5-c] ring compounds substituted with guanidino groups
|
US20180057486A1
(en)
|
2016-08-29 |
2018-03-01 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
US10144706B2
(en)
|
2016-09-01 |
2018-12-04 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
CN109923106B
(zh)
|
2016-09-02 |
2022-09-13 |
吉利德科学公司 |
toll样受体调节剂化合物
|
US10640499B2
(en)
|
2016-09-02 |
2020-05-05 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
WO2018043747A1
(ja)
|
2016-09-05 |
2018-03-08 |
国立大学法人京都大学 |
抗b型肝炎ウイルス剤
|
BE1024865B1
(fr)
|
2016-09-07 |
2018-07-31 |
Glaxosmithkline Biologicals Sa |
Derives d'imidazoquinoleine
|
DK3510033T3
(da)
|
2016-09-09 |
2022-02-28 |
Novartis Ag |
Forbindelser og sammensætninger som inhibitorer af endosomale toll-lignende receptorer
|
WO2018045911A1
(zh)
|
2016-09-09 |
2018-03-15 |
浙江海正药业股份有限公司 |
二氢嘧啶类化合物及其制备方法和用途
|
US10660877B2
(en)
|
2016-09-09 |
2020-05-26 |
Bristol-Myers Squibb Company |
Pyridyl substituted indole compounds
|
WO2018051254A1
(en)
|
2016-09-14 |
2018-03-22 |
Aurigene Discovery Technologies Limited |
Cyclic substituted-1,2,4-oxadiazole compounds as immunomodulators
|
WO2018051255A1
(en)
|
2016-09-14 |
2018-03-22 |
Aurigene Discovery Technologies Limited |
Cyclic substituted-1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
EP3523287B1
(en)
|
2016-10-04 |
2021-09-01 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene compounds as sting agonists
|
EP3523314A1
(de)
|
2016-10-07 |
2019-08-14 |
Biolog Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH |
Benzimidazolhaltige cyclische dinukleotide, verfahren zu deren herstellung und ihre verwendung zur aktivierung von stimulator von interferongenen (sting)-abhängigen signalwegen
|
CA3040033A1
(en)
|
2016-10-20 |
2018-04-26 |
Aurigene Discovery Technologies Limited |
Substituted 1,2,4-oxadiazole compounds as dual inhibitors of vista and pd-1 pathways
|
EP3532069A4
(en)
|
2016-10-26 |
2020-05-13 |
Merck Sharp & Dohme Corp. |
ARYL-AMIDE PHOSPHODIAMIDE COMPOUNDS ANTIVIRALS
|
WO2018078149A1
(en)
|
2016-10-31 |
2018-05-03 |
F. Hoffmann-La Roche Ag |
Novel cyclicsulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection
|
US10988507B2
(en)
|
2016-11-07 |
2021-04-27 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EP3538513A1
(en)
|
2016-11-11 |
2019-09-18 |
Dynavax Technologies Corporation |
Toll-like receptor antagonist compounds and methods of use
|
WO2018086593A1
(zh)
|
2016-11-11 |
2018-05-17 |
礼沃(上海)医药科技有限公司 |
含氮杂环化合物、制备方法、中间体、药物组合物和应用
|
JOP20170188A1
(ar)
|
2016-11-25 |
2019-01-30 |
Janssen Biotech Inc |
ثنائي النوكليوتيدات الحلقية كمنبهات ستينغ (sting)
|
JP7145854B2
(ja)
|
2016-11-28 |
2022-10-03 |
ジエンス ヘンルイ メデイシンカンパニー リミテッド |
ピラゾロ‐ヘテロアリール誘導体、その製造方法及び医学的用途
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
ES2891528T3
(es)
|
2016-12-20 |
2022-01-28 |
Bristol Myers Squibb Co |
Compuestos útiles como inmunomoduladores
|
RU2019122602A
(ru)
|
2016-12-20 |
2021-01-22 |
Мерк Шарп И Доум Корп. |
Комбинации антагонистов pd-1 и циклических динуклеотидных агонистов sting для лечения рака
|
CA3047113A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Cyclic dinucleotide sting agonists for cancer treatment
|
EP3558322B1
(en)
|
2016-12-22 |
2021-09-29 |
Merck Sharp & Dohme Corp. |
Antiviral benzyl-amine phosphodiamide compounds
|
WO2018119236A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Triazolo[1,5-a]pyridine derivatives as immunomodulators
|
US20180177784A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
US20180179202A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
WO2018119013A1
(en)
|
2016-12-22 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antiviral aliphatic ester prodrugs of tenofovir
|
WO2018119221A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
WO2018119266A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
PL3759109T3
(pl)
*
|
2018-02-26 |
2024-03-04 |
Gilead Sciences, Inc. |
Podstawione związki pirolizyny jako inhibitory replikacji hbv
|