WO2013096744A1
(en)
|
2011-12-21 |
2013-06-27 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
CN104902885A
(zh)
|
2012-08-28 |
2015-09-09 |
爱尔兰詹森科学公司 |
氨磺酰基-芳基酰胺和其作为药物用于治疗乙型肝炎的用途
|
US10125094B2
(en)
|
2013-02-28 |
2018-11-13 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis B
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
CA2922302C
(en)
|
2013-04-03 |
2021-08-03 |
Janssen Sciences Ireland Uc |
N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
HUE040446T2
(hu)
|
2013-05-17 |
2019-03-28 |
Janssen Sciences Ireland Uc |
Szulfamoiltiofenamid-származékok és gyógyszerként történõ alkalmazásuk hepatitis B kezelésére
|
LT3024819T
(lt)
|
2013-07-25 |
2018-06-11 |
Janssen Sciences Ireland Uc |
Pirolamido dariniai, turintys glioksamido pakaitų, ir jų panaudojimas kaip vaistų hepatito b gydymui
|
KR102290189B1
(ko)
|
2013-10-23 |
2021-08-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
카르복스아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
RU2702109C1
(ru)
|
2014-02-05 |
2019-10-04 |
Новира Терапьютикс, Инк. |
Комбинированная терапия для лечения инфекций вгв
|
EA035848B1
(ru)
|
2014-02-06 |
2020-08-20 |
Янссен Сайенсиз Айрлэнд Юси |
Производные сульфамоилпирроламида и их применение в качестве медикаментов для лечения гепатита b
|
CN106413402B
(zh)
|
2014-03-13 |
2020-10-30 |
美国印第安纳大学研究和技术公司 |
乙型肝炎核心蛋白变构调节剂
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
CN107106546A
(zh)
*
|
2014-10-06 |
2017-08-29 |
弗拉特利发现实验室有限责任公司 |
三唑并吡啶化合物和用于治疗囊性纤维化的方法
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
DK3321265T3
(da)
|
2015-03-04 |
2020-06-08 |
Gilead Sciences Inc |
4,6-diamino-pyrido[3,2-d]pyrimidinforbindelser og deres udnyttelse som modulatorer af toll-lignende receptorer
|
EA201792069A1
(ru)
|
2015-03-19 |
2018-04-30 |
Новира Терапьютикс, Инк. |
Производные азокана и азонана и способы лечения инфекций гепатита в
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
WO2017035230A1
(en)
|
2015-08-26 |
2017-03-02 |
Gilead Sciences, Inc. |
Deuterated toll-like receptor modulators
|
TWI786639B
(zh)
|
2015-09-15 |
2022-12-11 |
美商艾森伯利生物科學公司 |
B型肝炎核心蛋白質調節劑
|
AR106192A1
(es)
|
2015-09-29 |
2017-12-20 |
Novira Therapeutics Inc |
Formas cristalinas de un agente antiviral contra la hepatitis b
|
AU2017248828A1
(en)
|
2016-04-15 |
2018-11-01 |
Janssen Sciences Ireland Uc |
Combinations and methods comprising a capsid assembly inhibitor
|
CN109641874A
(zh)
|
2016-05-10 |
2019-04-16 |
C4医药公司 |
用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体
|
CN109562107A
(zh)
|
2016-05-10 |
2019-04-02 |
C4医药公司 |
用于靶蛋白降解的杂环降解决定子体
|
EP3454862A4
(en)
|
2016-05-10 |
2020-02-12 |
C4 Therapeutics, Inc. |
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN REDUCTION
|
CN109153682B
(zh)
|
2016-05-20 |
2021-05-25 |
豪夫迈·罗氏有限公司 |
用于治疗感染性疾病的具有氧、硫和氮连接基的新的吡嗪化合物
|
CN109414508A
(zh)
|
2016-05-27 |
2019-03-01 |
吉利德科学公司 |
使用ns5a、ns5b或ns3抑制剂治疗乙型肝炎病毒感染的方法
|
BR102017010009A2
(pt)
|
2016-05-27 |
2017-12-12 |
Gilead Sciences, Inc. |
Compounds for the treatment of hepatitis b virus infection
|
JP7034133B2
(ja)
|
2016-07-14 |
2022-03-11 |
エフ.ホフマン-ラ ロシュ アーゲー |
感染性疾患の処置のためのカルボキシ 6,7-ジヒドロ-4H-ピラゾロ[1,5-a]ピラジン化合物
|
CN109476668B
(zh)
|
2016-07-14 |
2022-03-22 |
豪夫迈·罗氏有限公司 |
用于治疗感染性疾病的6,7-二氢-4H-吡唑并[1,5-a]吡嗪和6,7-二氢-4H-三唑并[1,5-a]吡嗪化合物
|
WO2018011100A1
(en)
|
2016-07-14 |
2018-01-18 |
F. Hoffmann-La Roche Ag |
Novel tetrahydropyrazolopyridine compounds for the treatment of infectious diseases
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
US10640499B2
(en)
|
2016-09-02 |
2020-05-05 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
CN109923106B
(zh)
|
2016-09-02 |
2022-09-13 |
吉利德科学公司 |
toll样受体调节剂化合物
|
CN109937201A
(zh)
|
2016-09-15 |
2019-06-25 |
组装生物科学股份有限公司 |
乙型肝炎核心蛋白调节剂
|
CR20190181A
(es)
|
2016-10-14 |
2019-08-21 |
Prec Biosciences Inc |
Meganucleasas diseñadas específicamente para el reconocimiento de secuencias en el genoma del virus de la hepatitis b.
|
CN110088104B
(zh)
*
|
2016-11-03 |
2022-04-12 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒感染的四氢吡啶并嘧啶化合物
|
EP3534903B1
(en)
|
2016-11-07 |
2022-08-03 |
Arbutus Biopharma Corporation |
Substituted pyridinone-containing tricyclic compounds, and methods using same
|
TW202402300A
(zh)
|
2017-01-31 |
2024-01-16 |
美商基利科學股份有限公司 |
替諾福韋埃拉酚胺(tenofovir alafenamide)之晶型
|
JOP20180008A1
(ar)
|
2017-02-02 |
2019-01-30 |
Gilead Sciences Inc |
مركبات لعلاج إصابة بعدوى فيروس الالتهاب الكبدي b
|
RU2650610C1
(ru)
|
2017-02-28 |
2018-04-16 |
Васильевич Иващенко Александр |
Противовирусная композиция и способ ее применения
|
CN110621672A
(zh)
|
2017-03-02 |
2019-12-27 |
组装生物科学股份有限公司 |
环状磺酰胺化合物及其使用方法
|
EP3601216B1
(en)
|
2017-03-21 |
2023-10-25 |
Arbutus Biopharma Corporation |
Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same for the treatment of hepatitis b virus infection
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
WO2019040102A1
(en)
|
2017-08-22 |
2019-02-28 |
Gilead Sciences, Inc. |
THERAPEUTIC HETEROCYCLIC COMPOUNDS
|
EP3704119A1
(en)
|
2017-11-02 |
2020-09-09 |
AiCuris GmbH & Co. KG |
Novel, highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis b virus (hbv)
|
EA202091113A1
(ru)
|
2017-11-02 |
2020-08-28 |
Айкурис Гмбх Унд Ко. Кг |
Новые высокоактивные аминотиазолзамещенные индол-2-карбоксамиды, активные в отношении вируса гепатита b (hbv)
|
WO2019123340A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
CA3084582A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
CA3091015C
(en)
|
2018-02-13 |
2023-02-21 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
US10836769B2
(en)
|
2018-02-26 |
2020-11-17 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds and uses thereof
|
WO2019175657A1
(en)
|
2018-03-14 |
2019-09-19 |
Janssen Sciences Ireland Unlimited Company |
Capsid assembly modulator dosing regimen
|
EP3774883A1
(en)
|
2018-04-05 |
2021-02-17 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
CA3093888A1
(en)
|
2018-04-06 |
2019-10-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides
|
TW201945388A
(zh)
|
2018-04-12 |
2019-12-01 |
美商精密生物科學公司 |
對b型肝炎病毒基因體中之識別序列具有特異性之最佳化之經工程化巨核酸酶
|
US10899735B2
(en)
|
2018-04-19 |
2021-01-26 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
US20190359645A1
(en)
|
2018-05-03 |
2019-11-28 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides comprising carbocyclic nucleotide
|
JP7049519B2
(ja)
|
2018-07-06 |
2022-04-06 |
ギリアード サイエンシーズ, インコーポレイテッド |
治療用複素環式化合物
|
US11186579B2
(en)
|
2018-07-06 |
2021-11-30 |
Gilead Sciences, Inc. |
Therapeutic heterocyclic compounds
|
JP7105359B2
(ja)
|
2018-07-13 |
2022-07-22 |
ギリアード サイエンシーズ, インコーポレイテッド |
Pd-1/pd-l1阻害剤
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
AU2019364352A1
(en)
|
2018-10-22 |
2021-06-03 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of HBV
|
WO2020086556A1
(en)
|
2018-10-24 |
2020-04-30 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
CN112969505B
(zh)
|
2018-10-31 |
2023-11-14 |
吉利德科学公司 |
具有hpk1抑制活性的取代的6-氮杂苯并咪唑化合物
|
MX2021005047A
(es)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences Inc |
Compuestos de 6-azabenzimidazol sustituidos como inhibidores de hpk1.
|
EP3873488A4
(en)
|
2018-10-31 |
2022-08-03 |
The University of Sydney |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRUS INFECTION
|
AR116948A1
(es)
|
2018-11-02 |
2021-06-30 |
Aicuris Gmbh & Co Kg |
Derivados de urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas activas contra el virus de la hepatitis b (vhb)
|
UY38434A
(es)
|
2018-11-02 |
2020-05-29 |
Aicuris Gmbh & Co Kg |
Nuevas 6,7-dihidro-4h-pirazolo[1,5-a]pirazin indol-2-carboxamidas activas contra el virus de la hepatitis b (hbv)
|
AR116947A1
(es)
|
2018-11-02 |
2021-06-30 |
Aicuris Gmbh & Co Kg |
Derivados de urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas-indol-2-carboxamidas activas contra el virus de la hepatitis b (vhb)
|
US20220009945A1
(en)
|
2018-11-02 |
2022-01-13 |
Aicuris Gmbh & Co. Kg |
Novel urea 6,7-dihydro-4h-thiazole[5,4-c]pyridines active against the hepatitis b virus (hbv)
|
AR116946A1
(es)
|
2018-11-02 |
2021-06-30 |
Aicuris Gmbh & Co Kg |
Derivados de urea 6,7-dihidro-4h-pirazolo[4,3-c]piridinas activas contra el virus de la hepatitis b (vhb)
|
UY38437A
(es)
|
2018-11-02 |
2020-05-29 |
Aicuris Gmbh & Co Kg |
Nuevas urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas activas contra el virus de la hepatitis b (hbv)
|
TWI827760B
(zh)
|
2018-12-12 |
2024-01-01 |
加拿大商愛彼特生物製藥公司 |
經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法
|
EP3897631A4
(en)
|
2018-12-20 |
2022-11-23 |
C4 Therapeutics, Inc. |
TARGETED PROTEIN DEGRADATION
|
AU2020223865A1
(en)
|
2019-02-22 |
2021-07-15 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of HBV infection or HBV-induced diseases
|
CA3129011C
(en)
|
2019-03-07 |
2023-12-19 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
EP3935065A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
EP3934757B1
(en)
|
2019-03-07 |
2023-02-22 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
WO2020221824A1
(en)
|
2019-04-30 |
2020-11-05 |
Aicuris Gmbh & Co. Kg |
Novel indolizine-2-carboxamides active against the hepatitis b virus (hbv)
|
BR112021021564A2
(pt)
|
2019-04-30 |
2022-01-04 |
Aicuris Gmbh & Co Kg |
Indol-2-carboxamidas inovadoras ativas contra o vírus da hepatite b (hbv)
|
JP2022531199A
(ja)
|
2019-04-30 |
2022-07-06 |
アイクリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
B型肝炎ウイルス(hbv)に対し活性な新規のフェニル及びピリジル尿素
|
JP2022533008A
(ja)
|
2019-04-30 |
2022-07-21 |
アイクリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
B型肝炎ウイルス(hbv)に対し活性な新規のオキサリルピペラジン
|
MX2021013594A
(es)
|
2019-05-06 |
2021-12-10 |
Janssen Sciences Ireland Unlimited Co |
Derivados de amida utiles en el tratamiento de la infeccion por vhb o de enfermedades inducidas por vhb.
|
TWI826690B
(zh)
|
2019-05-23 |
2023-12-21 |
美商基利科學股份有限公司 |
經取代之烯吲哚酮化物及其用途
|
KR20220043931A
(ko)
|
2019-05-24 |
2022-04-05 |
어셈블리 바이오사이언시스, 인크. |
Hbv의 치료를 위한 제약 조성물
|
CA3140708A1
(en)
|
2019-06-18 |
2020-12-24 |
Helen Horton |
Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives
|
CA3142513A1
(en)
|
2019-06-25 |
2020-12-30 |
Gilead Sciences, Inc. |
Flt3l-fc fusion proteins and methods of use
|
WO2021011891A1
(en)
|
2019-07-18 |
2021-01-21 |
Gilead Sciences, Inc. |
Long-acting formulations of tenofovir alafenamide
|
US20220296619A1
(en)
|
2019-08-19 |
2022-09-22 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
US11497808B2
(en)
|
2019-09-30 |
2022-11-15 |
Gilead Sciences, Inc. |
HBV vaccines and methods treating HBV
|
EP4069729A1
(en)
|
2019-12-06 |
2022-10-12 |
Precision BioSciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the hepatitis b virus genome
|
CN111303118B
(zh)
*
|
2020-02-17 |
2021-11-09 |
清华大学 |
化合物及其在治疗乙型肝炎中的用途
|
CN115605493A
(zh)
|
2020-03-20 |
2023-01-13 |
吉利德科学公司(Us) |
4′-c-取代的-2-卤代-2′-脱氧腺苷核苷的前药及其制备和使用方法
|
IL297305A
(en)
|
2020-04-22 |
2022-12-01 |
Assembly Biosciences Inc |
The heteroaryl carboxamide compounds of pentadentate compounds for the treatment of HBV
|
WO2021216661A1
(en)
|
2020-04-22 |
2021-10-28 |
Assembly Biosciences, Inc. |
Pyrazole carboxamide compounds for treatment of hbv
|
US20230295096A1
(en)
|
2020-04-22 |
2023-09-21 |
Assembly Biosciences, Inc. |
Pyrazole carboxamide compounds for treatment of hbv
|
WO2021216660A1
(en)
|
2020-04-22 |
2021-10-28 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
KR20230048118A
(ko)
|
2020-08-07 |
2023-04-10 |
길리애드 사이언시즈, 인코포레이티드 |
포스폰아미드 뉴클레오티드 유사체의 프로드러그 및 이의 약학적 용도
|
TW202406932A
(zh)
|
2020-10-22 |
2024-02-16 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
EP4337223A1
(en)
|
2021-05-13 |
2024-03-20 |
Gilead Sciences, Inc. |
Combination of a tlr8 modulating compound and anti-hbv sirna therapeutics
|
AU2022299051A1
(en)
|
2021-06-23 |
2023-12-07 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
CN117396478A
(zh)
|
2021-06-23 |
2024-01-12 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|
CR20230585A
(es)
|
2021-06-23 |
2024-02-19 |
Gilead Sciences Inc |
Compuestos Moduladores de Diacilglicerol Quinasa.
|
KR20240023628A
(ko)
|
2021-06-23 |
2024-02-22 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
WO2023069545A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
WO2023069547A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
WO2023069544A1
(en)
|
2021-10-20 |
2023-04-27 |
Assembly Biosciences, Inc. |
5-membered heteroaryl carboxamide compounds for treatment of hbv
|
WO2023164183A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
WO2023164181A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
WO2023164179A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|
WO2023164186A1
(en)
|
2022-02-25 |
2023-08-31 |
Assembly Biosciences, Inc. |
Benzothia(dia)zepine compounds for treatment of hbv and hdv
|