NO843719L - Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen - Google Patents

Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen

Info

Publication number
NO843719L
NO843719L NO843719A NO843719A NO843719L NO 843719 L NO843719 L NO 843719L NO 843719 A NO843719 A NO 843719A NO 843719 A NO843719 A NO 843719A NO 843719 L NO843719 L NO 843719L
Authority
NO
Norway
Prior art keywords
expression
procedure
formation
heterologous gene
plasmid
Prior art date
Application number
NO843719A
Other languages
English (en)
Other versions
NO165644C (no
NO165644B (no
Inventor
Denis G Kleid
Daniel G Yansura
Herbert L Heyneker
Guiseppe F Miozzari
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO843719L publication Critical patent/NO843719L/no
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to NO84843719A priority Critical patent/NO165644C/no
Publication of NO165644B publication Critical patent/NO165644B/no
Publication of NO165644C publication Critical patent/NO165644C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO84843719A 1980-03-24 1984-09-18 Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen. NO165644C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO84843719A NO165644C (no) 1980-03-24 1984-09-18 Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13329680A 1980-03-24 1980-03-24
NO810986A NO810986L (no) 1980-03-24 1981-03-23 Bakteriell polypeptid-ekspresjon under anvendelse av tryptofon-promoter-operator
NO84843719A NO165644C (no) 1980-03-24 1984-09-18 Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen.

Publications (3)

Publication Number Publication Date
NO843719L true NO843719L (no) 1981-09-25
NO165644B NO165644B (no) 1990-12-03
NO165644C NO165644C (no) 1991-03-13

Family

ID=22457906

Family Applications (3)

Application Number Title Priority Date Filing Date
NO810986A NO810986L (no) 1980-03-24 1981-03-23 Bakteriell polypeptid-ekspresjon under anvendelse av tryptofon-promoter-operator
NO84843719A NO165644C (no) 1980-03-24 1984-09-18 Fremgangsmaate for dannelse av et ekspresjonsplasmid for ekspresjon av et heterologt gen.
NO84843718A NO161572C (no) 1980-03-24 1984-09-18 Fremgangsmaate for spalting av dobbelttraadet dna.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO810986A NO810986L (no) 1980-03-24 1981-03-23 Bakteriell polypeptid-ekspresjon under anvendelse av tryptofon-promoter-operator

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO84843718A NO161572C (no) 1980-03-24 1984-09-18 Fremgangsmaate for spalting av dobbelttraadet dna.

Country Status (35)

Country Link
US (2) US5888808A (no)
EP (3) EP0036776B1 (no)
JP (3) JPH0724582B2 (no)
KR (2) KR830005351A (no)
AR (1) AR248050A1 (no)
AT (3) ATE34183T1 (no)
AU (3) AU542640B2 (no)
BG (3) BG46005A3 (no)
BR (1) BR8101712A (no)
CA (2) CA1198068A (no)
CS (3) CS238612B2 (no)
DD (3) DD204494A5 (no)
DE (5) DE3153606C2 (no)
DK (1) DK173085B1 (no)
DZ (1) DZ278A1 (no)
ES (3) ES8207220A1 (no)
FI (3) FI810876L (no)
FR (2) FR2480781B1 (no)
GB (1) GB2073203B (no)
GR (1) GR74818B (no)
HU (1) HU195534B (no)
IE (3) IE51893B1 (no)
IL (3) IL71885A (no)
IT (1) IT1144324B (no)
MX (1) MX7689E (no)
MY (1) MY8500896A (no)
NO (3) NO810986L (no)
NZ (3) NZ207660A (no)
OA (1) OA06774A (no)
PH (4) PH17537A (no)
PL (2) PL147727B1 (no)
PT (1) PT72716B (no)
YU (2) YU45534B (no)
ZA (1) ZA811368B (no)
ZW (1) ZW5481A1 (no)

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US5888808A (en) 1999-03-30
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EP0154133B1 (en) 1990-05-16
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