JP5523107B2 - グルタミニルシクラーゼの新規阻害剤 - Google Patents
グルタミニルシクラーゼの新規阻害剤 Download PDFInfo
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- JP5523107B2 JP5523107B2 JP2009538704A JP2009538704A JP5523107B2 JP 5523107 B2 JP5523107 B2 JP 5523107B2 JP 2009538704 A JP2009538704 A JP 2009538704A JP 2009538704 A JP2009538704 A JP 2009538704A JP 5523107 B2 JP5523107 B2 JP 5523107B2
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- Prior art keywords
- benzo
- oxadiazol
- imidazole
- compound
- alkyl
- Prior art date
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Landscapes
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| WO2010011947A2 (en) * | 2008-07-25 | 2010-01-28 | Abbott Laboratories | AMYLOID ß PEPTIDE ANALOGUES, OLIGOMERS THEREOF, PROCESSES FOR PREPARING AND COMPOSITIONS COMPRISING SAID ANALOGUES OR OLIGOMERS, AND THEIR USES |
| CN102695546B (zh) | 2009-09-11 | 2014-09-10 | 前体生物药物股份公司 | 作为谷氨酰胺酰环化酶抑制剂的杂环衍生物 |
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| CN102947705A (zh) | 2010-02-18 | 2013-02-27 | 前体生物药物股份公司 | 通过确定焦谷氨酸修饰的mcp-1诊断炎性疾病的方法和谷氨酰胺酰基环化酶抑制剂的筛选方法 |
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| CN101914094B (zh) * | 2010-07-29 | 2012-08-22 | 南京大学 | 1,3,4-噁二唑衍生物及其制法与在制备抗肿瘤药物中的应用 |
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| CN105384692B (zh) * | 2015-10-26 | 2018-06-29 | 深圳大学 | 一种谷氨酰胺酰基环化酶抑制剂 |
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| EP3521308B1 (en) | 2018-01-31 | 2024-03-13 | Vivoryon Therapeutics N.V. | Humanized and de-immunized antibodies |
| CN111320617A (zh) * | 2018-12-17 | 2020-06-23 | 华中科技大学 | 苯基噁二唑类衍生物及其制备方法与应用 |
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| EP1831172B1 (en) | 2004-12-28 | 2009-02-18 | Council of Scientific and Industrial Research | Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors |
| WO2006074265A2 (en) | 2005-01-06 | 2006-07-13 | Merck & Co., Inc. | Drug combination therapy and pharmaceutical compositions for treating inflammatory disorders |
| CA2594943A1 (en) | 2005-01-19 | 2006-07-27 | Merck & Co., Inc. | Aminomethyl beta-secretase inhibitors for the treatment of alzheimer's disease |
| TW200640529A (en) | 2005-02-28 | 2006-12-01 | Thomas Christian Lines | Composition for treating mental health disorders |
| US20080194698A1 (en) | 2005-03-07 | 2008-08-14 | Michael Hermanussen | Nmda Receptor Antagonists in the Medical Intervention of Metabolic Disorders |
| US7745470B2 (en) | 2005-03-10 | 2010-06-29 | Bristol-Myers Squibb Company | Isophthalates as beta-secretase inhibitors |
| FR2883285B1 (fr) | 2005-03-17 | 2007-05-18 | Sanofi Aventis Sa | Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl) -1,2,3,6-tetrahudro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique |
| PE20110071A1 (es) | 2005-05-19 | 2011-01-31 | Centocor Inc | Anticuerpos anti-mcp-1, composiciones y metodos |
| EP2082041B1 (en) | 2006-09-21 | 2018-03-14 | Probiodrug AG | Novel genes related to glutaminyl cyclase |
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2007
- 2007-11-28 SI SI200730921T patent/SI2091948T1/sl unknown
- 2007-11-28 US US11/946,101 patent/US9126987B2/en active Active
- 2007-11-28 AT AT07847471T patent/ATE554085T1/de active
- 2007-11-28 WO PCT/EP2007/062953 patent/WO2008065141A1/en not_active Ceased
- 2007-11-28 DK DK07847471.5T patent/DK2091948T3/da active
- 2007-11-28 JP JP2009538704A patent/JP5523107B2/ja not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2091948B1 (en) | 2012-04-18 |
| ATE554085T1 (de) | 2012-05-15 |
| US9126987B2 (en) | 2015-09-08 |
| JP2010511013A (ja) | 2010-04-08 |
| WO2008065141A1 (en) | 2008-06-05 |
| EP2091948A1 (en) | 2009-08-26 |
| DK2091948T3 (da) | 2012-07-23 |
| SI2091948T1 (sl) | 2012-07-31 |
| US20080214620A1 (en) | 2008-09-04 |
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