AU594014B2
(en)
*
|
1984-03-21 |
1990-03-01 |
Research Corporation Technologies, Inc. |
Recombinant DNA molecules
|
US5718893A
(en)
*
|
1984-04-15 |
1998-02-17 |
Foster; Preston F. |
Use of G-CSF to reduce acute rejection
|
DE3680613D1
(de)
*
|
1985-02-08 |
1991-09-05 |
Chugai Pharmaceutical Co Ltd |
Menschlicher granuloxcyt-kolonie-stimulierungsfaktor.
|
US5532341A
(en)
*
|
1985-03-28 |
1996-07-02 |
Sloan-Kettering Institute For Cancer Research |
Human pluripotent hematopoietic colony stimulating factor
|
US5078996A
(en)
*
|
1985-08-16 |
1992-01-07 |
Immunex Corporation |
Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
|
US6004548A
(en)
*
|
1985-08-23 |
1999-12-21 |
Amgen, Inc. |
Analogs of pluripotent granulocyte colony-stimulating factor
|
US4810643A
(en)
*
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
NZ218336A
(en)
*
|
1985-12-09 |
1991-08-27 |
Kirin Amgen Inc |
Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
|
DK203187A
(da)
*
|
1986-04-22 |
1987-10-23 |
Immunex Corp |
Human g-csf proteinekspression
|
GR871067B
(en)
*
|
1986-07-18 |
1987-11-19 |
Chugai Pharmaceutical Co Ltd |
Process for producing stable pharmaceutical preparation containing granulocyte colony stimulating factor
|
US5186931A
(en)
*
|
1986-08-06 |
1993-02-16 |
Ajinomoto Co., Inc. |
Composition and method for supporting bone marrow transplantation
|
EP0256843A1
(en)
*
|
1986-08-11 |
1988-02-24 |
Cetus Corporation |
Expression of g-csf and muteins thereof and their use
|
JPH0618781B2
(ja)
*
|
1986-10-18 |
1994-03-16 |
中外製薬株式会社 |
感染症治療剤
|
US6238889B1
(en)
*
|
1986-12-16 |
2001-05-29 |
Dsm N.V. |
Molecular cloning and expression of the Pro8 isoform of human IL-3
|
US5714581A
(en)
*
|
1986-12-23 |
1998-02-03 |
Kyowa Hakko Kogyo Co., Ltd. |
Polypeptide derivatives of human granulocyte colony stimulating factor
|
JP2618618B2
(ja)
*
|
1988-03-04 |
1997-06-11 |
協和醗酵工業株式会社 |
抗g−csf誘導体、nd28モノクローナル抗体
|
US5362853A
(en)
*
|
1986-12-23 |
1994-11-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Polypeptide derivatives of human granulocyte colony stimulating factor
|
US5194592A
(en)
*
|
1986-12-23 |
1993-03-16 |
Kyowa Hakko Kogyo Co. Ltd. |
Monoclonal antibodies to novel polypeptide derivatives of human granulocyte colony stimulating factor
|
NO176799C
(no)
|
1986-12-23 |
1995-05-31 |
Kyowa Hakko Kogyo Kk |
DNA som koder for et polypeptid, rekombinant plasmid som koder for og kan uttrykke et polypeptid og fremgangsmåte for fremstilling av dette polypeptid
|
US5214132A
(en)
*
|
1986-12-23 |
1993-05-25 |
Kyowa Hakko Kogyo Co., Ltd. |
Polypeptide derivatives of human granulocyte colony stimulating factor
|
US6384194B1
(en)
*
|
1987-12-16 |
2002-05-07 |
Dsm N.V. |
Expression and purification of human interleukin-3 and muteins thereof
|
GB2213821B
(en)
*
|
1987-12-23 |
1992-01-02 |
British Bio Technology |
Synthetic human granulocyte colony stimulating factor gene
|
US5599690A
(en)
*
|
1988-02-01 |
1997-02-04 |
Amgen Inc. |
Control of norleucine incorporation into recombinant proteins
|
CA1329119C
(en)
*
|
1988-03-29 |
1994-05-03 |
Milton David Goldenberg |
Cytotoxic therapy
|
US20030232010A2
(en)
*
|
1988-03-29 |
2003-12-18 |
Immunomedics, Inc. |
Improved cytotoxic therapy
|
EP0719860B1
(en)
*
|
1988-05-13 |
2009-12-16 |
Amgen Inc. |
Process for isolating and purifying G-CSF
|
US5070013A
(en)
*
|
1988-05-31 |
1991-12-03 |
Schering Corporation |
Immunochemical assay for human granulocyte-macrophage colony stimulating factor
|
US5082774A
(en)
*
|
1988-08-30 |
1992-01-21 |
The General Hospital Corporation |
Recombinant human nerve growth factor
|
US5218092A
(en)
*
|
1988-09-29 |
1993-06-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Modified granulocyte-colony stimulating factor polypeptide with added carbohydrate chains
|
US5104651A
(en)
*
|
1988-12-16 |
1992-04-14 |
Amgen Inc. |
Stabilized hydrophobic protein formulations of g-csf
|
US6166183A
(en)
*
|
1992-11-30 |
2000-12-26 |
Kirin-Amgen, Inc. |
Chemically-modified G-CSF
|
US20020177688A1
(en)
*
|
1988-12-22 |
2002-11-28 |
Kirin-Amgen, Inc., |
Chemically-modified G-CSF
|
CA2006596C
(en)
*
|
1988-12-22 |
2000-09-05 |
Rika Ishikawa |
Chemically-modified g-csf
|
WO1990012877A1
(en)
*
|
1989-04-19 |
1990-11-01 |
Cetus Corporation |
Multifunctional m-csf proteins and genes encoding therefor
|
US6254861B1
(en)
*
|
1989-05-23 |
2001-07-03 |
Chandra Choudhury |
Hematopoietic growth factor derived from T lymphocytes
|
US5605822A
(en)
*
|
1989-06-15 |
1997-02-25 |
The Regents Of The University Of Michigan |
Methods, compositions and devices for growing human hematopoietic cells
|
CA2062741A1
(en)
*
|
1989-06-15 |
1990-12-16 |
Stephen G. Emerson |
Methods, compositions and devices for growing cells
|
US5635386A
(en)
*
|
1989-06-15 |
1997-06-03 |
The Regents Of The University Of Michigan |
Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture
|
US5763266A
(en)
*
|
1989-06-15 |
1998-06-09 |
The Regents Of The University Of Michigan |
Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
|
US5665543A
(en)
*
|
1989-07-18 |
1997-09-09 |
Oncogene Science, Inc. |
Method of discovering chemicals capable of functioning as gene expression modulators
|
US5580722A
(en)
*
|
1989-07-18 |
1996-12-03 |
Oncogene Science, Inc. |
Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
|
US6203976B1
(en)
|
1989-07-18 |
2001-03-20 |
Osi Pharmaceuticals, Inc. |
Methods of preparing compositions comprising chemicals capable of transcriptional modulation
|
US5776502A
(en)
|
1989-07-18 |
1998-07-07 |
Oncogene Science, Inc. |
Methods of transcriptionally modulating gene expression
|
WO1991005798A1
(en)
*
|
1989-10-10 |
1991-05-02 |
Amgen Inc. |
Compositions and methods for treating or preventing infections in canine and feline animals
|
CA2025181A1
(en)
*
|
1989-10-12 |
1991-04-13 |
William G. Weisburg |
Nucleic acid probes and methods for detecting fungi
|
GEP20002145B
(en)
*
|
1989-10-16 |
2000-06-25 |
Amgen Inc Us |
Stem Cell Factor
|
US7144731B2
(en)
|
1989-10-16 |
2006-12-05 |
Amgen Inc. |
SCF antibody compositions and methods of using the same
|
US6852313B1
(en)
|
1989-10-16 |
2005-02-08 |
Amgen Inc. |
Method of stimulating growth of melanocyte cells by administering stem cell factor
|
ATE194651T1
(de)
*
|
1989-10-16 |
2000-07-15 |
Amgen Inc |
Stammzellenfaktor
|
US20040181044A1
(en)
*
|
1989-10-16 |
2004-09-16 |
Zsebo Krisztina M. |
Method of stimulating growth of epithelial cells by administering stem cell factor
|
ZA907921B
(en)
|
1989-10-16 |
1991-08-28 |
Amgen Inc |
Stem cell factor
|
US5214133A
(en)
*
|
1989-11-17 |
1993-05-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
SCL: a hematopoietic growth and differentiation factor
|
US5132212A
(en)
*
|
1989-11-17 |
1992-07-21 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Scl gene, and a hematopoietic growth and differentiation factor encoded thereby
|
JPH04218000A
(ja)
*
|
1990-02-13 |
1992-08-07 |
Kirin Amgen Inc |
修飾ポリペプチド
|
US5147799A
(en)
*
|
1990-04-25 |
1992-09-15 |
Isia Bursuker |
Repopulation of macrophages and granulocytes using transforming growth factor-beta
|
GB9107846D0
(en)
*
|
1990-04-30 |
1991-05-29 |
Ici Plc |
Polypeptides
|
US5399345A
(en)
*
|
1990-05-08 |
1995-03-21 |
Boehringer Mannheim, Gmbh |
Muteins of the granulocyte colony stimulating factor
|
US5258367A
(en)
*
|
1990-06-29 |
1993-11-02 |
University Of Florida |
Uteroferrin and rose proteins for stimulating hematopoietic cells
|
IE912365A1
(en)
*
|
1990-07-23 |
1992-01-29 |
Zeneca Ltd |
Continuous release pharmaceutical compositions
|
EP0526630A4
(en)
*
|
1991-02-22 |
1993-08-11 |
Amgen Inc. |
Use of gm-csf and g-csf to promote accelerated wound healing
|
DE69233336T2
(de)
*
|
1991-02-26 |
2005-03-31 |
Astrazeneca Ab |
Vektor
|
US6565841B1
(en)
|
1991-03-15 |
2003-05-20 |
Amgen, Inc. |
Pulmonary administration of granulocyte colony stimulating factor
|
FR2686899B1
(fr)
*
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
US6413509B1
(en)
|
1992-11-24 |
2002-07-02 |
S. Christopher Bauer |
Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factors
|
US6361977B1
(en)
|
1992-11-24 |
2002-03-26 |
S. Christopher Bauer |
Methods of using multivariant IL-3 hematopoiesis fusion protein
|
US5772992A
(en)
*
|
1992-11-24 |
1998-06-30 |
G.D. Searle & Co. |
Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
|
US6153183A
(en)
|
1992-11-24 |
2000-11-28 |
G. D. Searle & Company |
Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
|
US6057133A
(en)
*
|
1992-11-24 |
2000-05-02 |
G. D. Searle |
Multivariant human IL-3 fusion proteins and their recombinant production
|
US7091319B1
(en)
|
1992-11-24 |
2006-08-15 |
Bauer S Christopher |
IL-3 variant hematopoiesis fusion protein
|
US5738849A
(en)
*
|
1992-11-24 |
1998-04-14 |
G. D. Searle & Co. |
Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
|
US6361976B1
(en)
*
|
1992-11-24 |
2002-03-26 |
S. Christopher Bauer |
Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
|
US6403076B1
(en)
|
1992-11-24 |
2002-06-11 |
S. Christopher Bauer |
Compositions for increasing hematopoiesis with interleukin-3 mutants
|
US5581476A
(en)
*
|
1993-01-28 |
1996-12-03 |
Amgen Inc. |
Computer-based methods and articles of manufacture for preparing G-CSF analogs
|
AU2007200247B2
(en)
*
|
1993-01-28 |
2011-03-10 |
Amgen Inc. |
G-CSF analog compositions
|
EP0716148B1
(en)
|
1993-09-15 |
2004-01-02 |
Chiron Corporation |
Recombinant alphavirus vectors
|
US5874075A
(en)
*
|
1993-10-06 |
1999-02-23 |
Amgen Inc. |
Stable protein: phospholipid compositions and methods
|
US20050059149A1
(en)
*
|
1993-11-22 |
2005-03-17 |
Bauer S. Christopher |
Methods of ex-vivo expansion of hematopoeitic cells using multivariant IL-3 hematopoiesis chimera proteins
|
CA2139385C
(en)
*
|
1994-02-04 |
2001-12-25 |
Gottfried Alber |
Products containing g-csf and tnf binding protein
|
US5631219A
(en)
*
|
1994-03-08 |
1997-05-20 |
Somatogen, Inc. |
Method of stimulating hematopoiesis with hemoglobin
|
US6242417B1
(en)
|
1994-03-08 |
2001-06-05 |
Somatogen, Inc. |
Stabilized compositions containing hemoglobin
|
KR100203824B1
(ko)
*
|
1994-03-31 |
1999-06-15 |
스티븐 엠. 오드리 |
거핵구 성장 및 분화를 자극하기 위한 조성물 및방법
|
US5795569A
(en)
*
|
1994-03-31 |
1998-08-18 |
Amgen Inc. |
Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
|
US5536495A
(en)
*
|
1994-04-15 |
1996-07-16 |
Foster; Preston F. |
Use of G-CSF to reduce acute rejection
|
US20030053982A1
(en)
*
|
1994-09-26 |
2003-03-20 |
Kinstler Olaf B. |
N-terminally chemically modified protein compositions and methods
|
US5824784A
(en)
*
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
US6100070A
(en)
*
|
1995-10-05 |
2000-08-08 |
G. D. Searle & Co. |
G-CSF receptor agonists
|
US6066318A
(en)
|
1995-10-05 |
2000-05-23 |
G.D. Searle & Co. |
Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
|
WO1997038087A2
(en)
|
1996-04-05 |
1997-10-16 |
Chiron Corporation |
Alphaviral vector with reduced inhibition of cellular macromolecular synthesis
|
JP2001500738A
(ja)
|
1996-09-17 |
2001-01-23 |
カイロン コーポレイション |
細胞内疾患を処置するための組成物および方法
|
US6162426A
(en)
*
|
1997-05-05 |
2000-12-19 |
La Gamma; Edmund F. |
Use of G-CSF to enhance the immune system in neonates
|
CN1269805A
(zh)
|
1997-07-14 |
2000-10-11 |
博尔德生物技术公司 |
生长激素和相关蛋白的衍生物
|
US7495087B2
(en)
|
1997-07-14 |
2009-02-24 |
Bolder Biotechnology, Inc. |
Cysteine muteins in the C-D loop of human interleukin-11
|
US6753165B1
(en)
*
|
1999-01-14 |
2004-06-22 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
US7153943B2
(en)
|
1997-07-14 |
2006-12-26 |
Bolder Biotechnology, Inc. |
Derivatives of growth hormone and related proteins, and methods of use thereof
|
US20080076706A1
(en)
|
1997-07-14 |
2008-03-27 |
Bolder Biotechnology, Inc. |
Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
|
US6017876A
(en)
*
|
1997-08-15 |
2000-01-25 |
Amgen Inc. |
Chemical modification of granulocyte-colony stimulating factor (G-CSF) bioactivity
|
DE69821011T3
(de)
*
|
1997-10-02 |
2009-01-08 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Verfahren zur Modulierung der Neovaskularisierung und/oder des Wachstums kollateraler Arterien und/oder anderer Arterien aus bestehenden arteriolären Verbindungen
|
US20020034819A1
(en)
*
|
1998-02-23 |
2002-03-21 |
Alan K. Smith |
Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
|
US6541033B1
(en)
|
1998-06-30 |
2003-04-01 |
Amgen Inc. |
Thermosensitive biodegradable hydrogels for sustained delivery of leptin
|
CN1101403C
(zh)
*
|
1998-07-13 |
2003-02-12 |
金磊 |
粒细胞集落刺激因子的制备
|
US6979442B1
(en)
|
1998-08-17 |
2005-12-27 |
Pfizer Inc. |
Stabilized protein compositions
|
US5999474A
(en)
|
1998-10-01 |
1999-12-07 |
Monolithic System Tech Inc |
Method and apparatus for complete hiding of the refresh of a semiconductor memory
|
US6420339B1
(en)
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
US6245740B1
(en)
|
1998-12-23 |
2001-06-12 |
Amgen Inc. |
Polyol:oil suspensions for the sustained release of proteins
|
US6451346B1
(en)
*
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
US7935805B1
(en)
|
1998-12-31 |
2011-05-03 |
Novartis Vaccines & Diagnostics, Inc |
Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
|
AU2221600A
(en)
|
1998-12-31 |
2000-07-31 |
Chiron Corporation |
Improved expression of hiv polypeptides and production of virus-like particles
|
WO2000040728A1
(en)
|
1999-01-06 |
2000-07-13 |
Xencor, Inc. |
Nucleic acids and proteins corresponding to mutants of g-csf with granulopoietic activity
|
US7208473B2
(en)
*
|
1999-01-06 |
2007-04-24 |
Xencor, Inc. |
Nucleic acids and protein variants of hG-CSF with granulopoietic activity
|
US8288126B2
(en)
|
1999-01-14 |
2012-10-16 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
CA2359573C
(en)
|
1999-01-19 |
2010-04-20 |
Biostream, Inc. |
Conjugates of colony stimulating factors for targeting and imaging infection and inflammation
|
CZ300546B6
(cs)
*
|
1999-01-29 |
2009-06-10 |
Amgen, Inc. |
Fyziologicky aktivní konjugát, prostredek a zpusob prípravy
|
US6365583B1
(en)
|
1999-02-02 |
2002-04-02 |
Anormed, Inc. |
Methods to enhance white blood cell count
|
KR100356140B1
(ko)
*
|
1999-07-08 |
2002-10-19 |
한미약품공업 주식회사 |
인간 과립구 콜로니 자극인자 변이체 및 이의 생산 방법
|
US8106098B2
(en)
*
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
US6670323B1
(en)
*
|
1999-11-12 |
2003-12-30 |
Baxter International, Inc. |
Reduced side-effect hemoglobin compositions
|
US6555660B2
(en)
*
|
2000-01-10 |
2003-04-29 |
Maxygen Holdings Ltd. |
G-CSF conjugates
|
US6646110B2
(en)
*
|
2000-01-10 |
2003-11-11 |
Maxygen Holdings Ltd. |
G-CSF polypeptides and conjugates
|
US6831158B2
(en)
*
|
2000-01-10 |
2004-12-14 |
Maxygen Holdings Ltd. |
G-CSF conjugates
|
CA2395713C
(en)
|
2000-01-10 |
2012-04-10 |
Torben Lauesgaard Nissen |
G-csf conjugates
|
DK1129720T3
(da)
|
2000-02-29 |
2004-09-27 |
Pfizer Prod Inc |
Stabiliseret granulocyt-kolonistimulerende faktor
|
AU2001249755A1
(en)
*
|
2000-03-31 |
2001-10-15 |
Celgene Corporation |
Inhibition of cyclooxygenase-2 activity
|
CA2405557C
(en)
|
2000-04-12 |
2013-09-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US8435939B2
(en)
|
2000-09-05 |
2013-05-07 |
Biokine Therapeutics Ltd. |
Polypeptide anti-HIV agent containing the same
|
ATE348883T1
(de)
*
|
2000-09-08 |
2007-01-15 |
Massachusetts Inst Technology |
Zusammensetzungen und verfahren mit analogen von g-csf
|
US20020150979A1
(en)
*
|
2000-10-04 |
2002-10-17 |
Naokazu Naitou |
Process for producing a protein
|
DK1353672T3
(da)
*
|
2000-11-30 |
2008-01-21 |
Childrens Medical Center |
Syntese af 4-amino-thalidomidenantiomerer
|
EP1229045A1
(en)
|
2001-02-01 |
2002-08-07 |
Institut Curie |
Universal carrier for targeting molecules to Gb3 receptor expressing cells
|
WO2002069232A2
(en)
|
2001-02-19 |
2002-09-06 |
Merck Patent Gmbh |
Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
|
FR2820979B1
(fr)
|
2001-02-22 |
2004-03-12 |
Didier Pourquier |
Nouvelle application therapeutique du g-csf
|
US6956023B1
(en)
|
2001-04-19 |
2005-10-18 |
University Of Florida |
Materials and methods for providing nutrition to neonates
|
WO2003004620A2
(en)
|
2001-07-05 |
2003-01-16 |
Chiron, Corporation |
Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
|
US20030198621A1
(en)
|
2001-07-05 |
2003-10-23 |
Megede Jan Zur |
Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof
|
JP4444652B2
(ja)
|
2001-07-11 |
2010-03-31 |
マキシゲン・ホールディングズ・リミテッド |
G−csf結合体
|
NZ530169A
(en)
*
|
2001-07-31 |
2007-04-27 |
Anormed Inc |
Methods to mobilize progenitor/stem cells
|
US7169750B2
(en)
*
|
2001-07-31 |
2007-01-30 |
Anormed, Inc. |
Methods to mobilize progenitor/stem cells
|
US20030104996A1
(en)
*
|
2001-08-30 |
2003-06-05 |
Tiansheng Li |
L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
|
CN101724075B
(zh)
|
2001-10-10 |
2014-04-30 |
诺和诺德公司 |
肽的重构和糖缀合
|
EP2292273A3
(en)
|
2001-10-10 |
2011-11-23 |
BioGeneriX AG |
Remodeling and glycoconjugation of peptides
|
WO2004099231A2
(en)
|
2003-04-09 |
2004-11-18 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
SI21102A
(sl)
|
2001-12-19 |
2003-06-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
|
EP2261250B1
(en)
|
2001-12-21 |
2015-07-01 |
Human Genome Sciences, Inc. |
GCSF-Albumin fusion proteins
|
KR20030062854A
(ko)
*
|
2002-01-21 |
2003-07-28 |
주식회사 엘지생명과학 |
분비형 벡터를 이용한 효모에서의 재조합 단백질의 제조방법
|
US7557195B2
(en)
*
|
2002-03-20 |
2009-07-07 |
Biopolymed, Inc. |
Stoichiometric conjugates of biocompatible polymers at the unpaired cysteine residue of the wild-type G-CSF
|
US20030191056A1
(en)
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
US6790641B2
(en)
|
2002-05-01 |
2004-09-14 |
Cell Genesys, Inc. |
Lentiviral vector particles resistant to complement inactivation
|
US7968569B2
(en)
*
|
2002-05-17 |
2011-06-28 |
Celgene Corporation |
Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
IL165258A0
(en)
*
|
2002-05-17 |
2005-12-18 |
Celgene Corp |
Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
|
US7393862B2
(en)
*
|
2002-05-17 |
2008-07-01 |
Celgene Corporation |
Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
|
US20100129363A1
(en)
*
|
2002-05-17 |
2010-05-27 |
Zeldis Jerome B |
Methods and compositions using pde4 inhibitors for the treatment and management of cancers
|
MXPA04011311A
(es)
|
2002-05-17 |
2005-02-14 |
Celgene Corp |
Metodos y composiciones que utilizan compuestos inmunomoduladores para el tratamiento y el manejo de canceres y otras enfermedades.
|
US7323479B2
(en)
|
2002-05-17 |
2008-01-29 |
Celgene Corporation |
Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
|
USRE48890E1
(en)
|
2002-05-17 |
2022-01-11 |
Celgene Corporation |
Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation
|
US7081443B2
(en)
|
2002-05-21 |
2006-07-25 |
Korea Advanced Institutes Of Science And Technology (Kaist) |
Chimeric comp-ang1 molecule
|
AU2002345829A1
(en)
*
|
2002-06-24 |
2004-01-06 |
Dr. Reddy's Laboratories Ltd. |
Process for preparing g-csf
|
SI21273A
(sl)
*
|
2002-07-31 |
2004-02-29 |
LEK farmacevtska dru�ba d.d. |
Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
|
WO2004020462A1
(ja)
|
2002-08-27 |
2004-03-11 |
Fujii, Nobutaka |
Cxcr4拮抗薬およびその用途
|
CA2498319A1
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
US11116782B2
(en)
|
2002-10-15 |
2021-09-14 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
EP1900369A1
(en)
|
2002-10-15 |
2008-03-19 |
Celgene Corporation |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
|
US7842691B2
(en)
*
|
2002-10-15 |
2010-11-30 |
Celgene Corporation |
Method for the treatment of myelodysplastic syndromes using cyclopropanecarboxylic acid {2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-OXO-2,3-dihydro-1 H-isoindol-4-yl}-amide
|
US7189740B2
(en)
*
|
2002-10-15 |
2007-03-13 |
Celgene Corporation |
Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes
|
US8404716B2
(en)
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
US8404717B2
(en)
*
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes using lenalidomide
|
BR0316057A
(pt)
|
2002-11-06 |
2005-09-20 |
Celgene Corp |
Métodos de tratar, controlar ou prevenir um câncer especìfico e uma doença associada com angiogênese indesejada e de reduzir ou evitar um efeito adverso associado com a administração de um segundo ingrediente ativo e com a terapia de radiação, terapia hormonal, terapia biológica ou imunoterapia em um paciente sofrendo de um câncer especìfico, composição farmacêutica e kit
|
US20040171147A1
(en)
*
|
2002-11-26 |
2004-09-02 |
Hariri Robert J. |
Cytotherapeutics, cytotherapeutic units and methods for treatments using them
|
RU2353385C2
(ru)
*
|
2002-12-31 |
2009-04-27 |
Зигнис Байосайенс Гмбх Унд Ко. Кг |
Способы лечения неврологических состояний с применением гематопоэтических факторов роста
|
US7695723B2
(en)
|
2002-12-31 |
2010-04-13 |
Sygnis Bioscience Gmbh & Co. Kg |
Methods of treating neurological conditions with hematopoietic growth factors
|
US7785601B2
(en)
*
|
2002-12-31 |
2010-08-31 |
Sygnis Bioscience Gmbh & Co. Kg |
Methods of treating neurological conditions with hematopoietic growth factors
|
AU2004212009B2
(en)
*
|
2003-02-13 |
2010-07-29 |
Celularity Inc. |
Use of umbilical cord blood to treat individuals having a disease, disorder or condition
|
KR20050111759A
(ko)
|
2003-03-12 |
2005-11-28 |
셀진 코포레이션 |
7-아미노-이소인돌릴 화합물 및 그의 제약학적 용도
|
US8084424B2
(en)
*
|
2003-04-09 |
2011-12-27 |
University Of Utah Research Foundation |
Compositions and methods related to erythropoietin
|
AU2004232361A1
(en)
|
2003-04-22 |
2004-11-04 |
Anormed Inc. |
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
|
US7501518B2
(en)
*
|
2003-04-22 |
2009-03-10 |
Genzyme Corporation |
Methods of making 2,6-diaryl piperidine derivatives
|
US20070041937A1
(en)
*
|
2003-08-22 |
2007-02-22 |
The Council Of The Queensland Institute Of Medical Research |
G-csf derivative for inducing immunological tolerance
|
UA83504C2
(en)
*
|
2003-09-04 |
2008-07-25 |
Селджин Корпорейшн |
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
US7220407B2
(en)
*
|
2003-10-27 |
2007-05-22 |
Amgen Inc. |
G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
|
OA13284A
(en)
*
|
2003-11-06 |
2007-01-31 |
Corporation Celgene |
Methods and compositions using thalidomide for thetreatment and management of cancers and other dis eases.
|
AU2004296765B2
(en)
*
|
2003-12-02 |
2011-03-24 |
Celgene Corporation |
Methods and compositions for the treatment and management of hemoglobinopathy and anemia
|
JP2007517042A
(ja)
|
2003-12-30 |
2007-06-28 |
デュレクト コーポレーション |
活性物質、好ましくはgnrhの制御放出のための、好ましくはpegおよびplgの混合物を含有するポリマーインプラント
|
JP4896745B2
(ja)
|
2004-02-02 |
2012-03-14 |
アンブレツクス・インコーポレイテツド |
修飾されたヒトインターフェロンポリペプチドおよびこれらの使用
|
SE0400942D0
(sv)
*
|
2004-04-08 |
2004-04-08 |
Henrik Arnberg |
Composition and method
|
BRPI0418742A
(pt)
*
|
2004-04-14 |
2007-09-11 |
Celgene Corp |
métodos de tratamento, prevenção ou controle de uma sìndrome mielodisplásica, de redução ou evitação de um efeito adverso associado com a administração de um segundo ingrediente ativo em um paciente sofrendo de um sìndrome mielodisplásica, composição farmacêutica, forma de dosagem unitária única, e, kit
|
BRPI0418743A
(pt)
*
|
2004-04-14 |
2007-09-18 |
Celgene Corp |
métodos de tratamento, prevenção ou controle de uma sìndrome mielodisplásica, de redução ou evitação de um efeito adverso associado com a administração de um segundo ingrediente ativo em um paciente sofrendo de uma sìndrome mielodisplásica, composição farmacêutica, forma de dosagem unitária única, e, kit
|
EP1586334A1
(en)
*
|
2004-04-15 |
2005-10-19 |
TRASTEC scpa |
G-CSF conjugates with peg
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
CA2576030A1
(en)
*
|
2004-08-09 |
2006-02-23 |
Alios Biopharma Inc. |
Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same
|
BRPI0514343A
(pt)
*
|
2004-08-13 |
2008-06-10 |
Anormed Inc |
combinações de quimiocinas para mobilizar células progenitoras/tronco
|
AU2005282449B2
(en)
|
2004-09-07 |
2011-07-14 |
Velico Medical, Inc. |
Apparatus for prolonging survival of platelets
|
WO2007047687A2
(en)
*
|
2005-10-14 |
2007-04-26 |
Zymequest, Inc. |
Compositions and methods for prolonging survival of platelets
|
US7691365B2
(en)
|
2004-09-28 |
2010-04-06 |
Aprogen, Inc. |
Methods of using chimeric coiled coil molecule to treat ischemic disease
|
GB0505353D0
(en)
|
2005-03-16 |
2005-04-20 |
Chem Technologies Ltd E |
Treatment process for concrete
|
CN101072585A
(zh)
|
2004-11-01 |
2007-11-14 |
诺华疫苗和诊断公司 |
产生免疫应答的组合方法
|
WO2006055260A2
(en)
*
|
2004-11-05 |
2006-05-26 |
Northwestern University |
Use of scf and g-csf in the treatment of cerebral ischemia and neurological disorders
|
EP1828241A1
(en)
*
|
2004-12-23 |
2007-09-05 |
Laboratoires Serono S.A. |
G-csf polypeptides and uses thereof
|
US9029331B2
(en)
|
2005-01-10 |
2015-05-12 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
EP1841787A2
(en)
|
2005-01-25 |
2007-10-10 |
Cell Therapeutics, Inc. |
Conjugates of biologically active proteins having a modified in vivo half-life
|
US20060270707A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Zeldis Jerome B |
Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus
|
JP5137821B2
(ja)
*
|
2005-06-01 |
2013-02-06 |
マキシジェン, インコーポレイテッド |
Peg化されたg−csfポリペプチドおよびその製造方法
|
EP1739179A1
(en)
|
2005-06-30 |
2007-01-03 |
Octapharma AG |
Serum-free stable transfection and production of recombinant human proteins in human cell lines
|
DE102005033250A1
(de)
|
2005-07-15 |
2007-01-18 |
Bioceuticals Arzneimittel Ag |
Verfahren zur Reinigung von G-CSF
|
KR100735784B1
(ko)
*
|
2005-07-20 |
2007-07-06 |
재단법인 목암생명공학연구소 |
인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물
|
CA2617064A1
(en)
*
|
2005-08-04 |
2007-02-15 |
Nektar Therapeutics Al, Corporation |
Conjugates of a g-csf moiety and a polymer
|
US8580814B2
(en)
*
|
2006-04-03 |
2013-11-12 |
Sunesis Pharmaceuticals, Inc. |
Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
|
US20080138295A1
(en)
*
|
2005-09-12 |
2008-06-12 |
Celgene Coporation |
Bechet's disease using cyclopropyl-N-carboxamide
|
US20070155791A1
(en)
*
|
2005-12-29 |
2007-07-05 |
Zeldis Jerome B |
Methods for treating cutaneous lupus using aminoisoindoline compounds
|
WO2007106063A2
(en)
*
|
2006-02-24 |
2007-09-20 |
Genzyme Corporation |
Methods for increasing blood flow and/or promoting tissue regeneration
|
DE102006009437A1
(de)
|
2006-03-01 |
2007-09-13 |
Bioceuticals Arzneimittel Ag |
G-CSF-Flüssigformulierung
|
WO2007102814A2
(en)
*
|
2006-03-07 |
2007-09-13 |
Regenetech, Inc. |
Recombinant mammalian molecules and method for production thereof
|
GB0605684D0
(en)
*
|
2006-03-21 |
2006-05-03 |
Sicor Biotech Uab |
Method For Purifying Granulocyte-Colony Stimulating Factor
|
US20100196336A1
(en)
|
2006-05-23 |
2010-08-05 |
Dongsu Park |
Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
|
CA2654876A1
(en)
|
2006-06-12 |
2007-12-21 |
Sunesis Pharmaceuticals, Inc. |
1-8-naphthyridine compounds for the treatment of cancer
|
WO2008016702A2
(en)
|
2006-08-02 |
2008-02-07 |
Sunesis Pharmaceuticals, Inc. |
Combined use of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1(2-thiazolyl)-1,8-naphthyridine-3-carboxylic
|
CL2007002218A1
(es)
|
2006-08-03 |
2008-03-14 |
Celgene Corp Soc Organizada Ba |
Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa.
|
AR062271A1
(es)
*
|
2006-08-07 |
2008-10-29 |
Genzyme Corp |
Uso de una cantidad efectiva de al menos un inhibidor de cxcr4, al menos un agonista de cxcr2 y g-csf para movilizar las celulas progenitoras y/o celulas madre
|
EP3011961B1
(en)
|
2006-12-21 |
2020-11-11 |
Biokine Therapeutics LTD. |
4f-benzoyl-tn14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation
|
WO2008096370A2
(en)
*
|
2007-02-05 |
2008-08-14 |
Natco Pharma Limited |
An efficient and novel purification method of recombinant hg-csf
|
WO2008137471A2
(en)
*
|
2007-05-02 |
2008-11-13 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
EP3173414A1
(en)
*
|
2007-07-17 |
2017-05-31 |
ACEA Biosciences Inc. |
Heterocyclic compounds and uses as anticancer agents
|
WO2009020590A1
(en)
*
|
2007-08-07 |
2009-02-12 |
Celgene Corporation |
Methods for treating lymphomas in certain patient populations and screening patients for said therapy
|
EP2581441A1
(en)
|
2007-08-09 |
2013-04-17 |
Genzyme Corporation |
Method of treating autoimmune disease with mesenchymal stem cells
|
PT2197919E
(pt)
|
2007-08-27 |
2014-07-17 |
Ratiopharm Gmbh |
Formulação líquida de conjugado de g-csf
|
EP2076243B9
(de)
|
2007-08-27 |
2015-01-14 |
ratiopharm GmbH |
Flüssigformulierung von g-csf
|
US8758761B2
(en)
*
|
2007-09-30 |
2014-06-24 |
University Of Florida Research Foundation, Inc. |
Combination therapies for treating type 1 diabetes
|
KR100921226B1
(ko)
|
2007-10-04 |
2009-10-12 |
학교법인 선목학원 |
사람 혈액의 과립구집락자극인자(hG-CSF) 유전자를 내장하는 레트로바이러스 발현벡터 및 이에 의해 형질전환된 가금
|
US20090155838A1
(en)
*
|
2007-11-28 |
2009-06-18 |
Smart Tube, Inc. |
Devices, systems and methods for the collection, stimulation, stabilization, and analysis of a biological sample
|
WO2009075841A2
(en)
|
2007-12-10 |
2009-06-18 |
Sunesis Pharmaceuticals, Inc. |
Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
|
CA2712606A1
(en)
|
2008-02-08 |
2009-08-13 |
Ambrx, Inc. |
Modified leptin polypeptides and their uses
|
NZ588877A
(en)
*
|
2008-04-30 |
2012-08-31 |
Neutron Row |
Methods of using corticotropin-releasing factor for the treatment of cancer
|
WO2009139888A1
(en)
|
2008-05-15 |
2009-11-19 |
Celgene Corporation |
Oral formulations of cytidine analogs and methods of use thereof
|
NZ600382A
(en)
|
2008-07-23 |
2013-11-29 |
Ambrx Inc |
Modified bovine G-CSF polypeptides and their uses
|
WO2010092571A2
(en)
|
2009-02-11 |
2010-08-19 |
Yeda Research And Development Co. Ltd. |
Short beta-defensin-derived peptides
|
JP5645816B2
(ja)
|
2009-05-25 |
2014-12-24 |
国立大学法人東京工業大学 |
中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物
|
JP5715622B2
(ja)
|
2009-06-14 |
2015-05-07 |
バイオカイン セラピューティックス リミテッド |
血小板レベルを増大させるためのペプチド療法
|
WO2011005488A1
(en)
|
2009-06-22 |
2011-01-13 |
Amgen Inc. |
Refolding proteins using a chemically controlled redox state
|
CN102481342A
(zh)
|
2009-06-24 |
2012-05-30 |
S·伊万斯-弗里克 |
使用促皮质素释放因子治疗癌症的方法
|
JP2012531428A
(ja)
|
2009-06-25 |
2012-12-10 |
アムジエン・インコーポレーテツド |
哺乳類以外の系で発現されるタンパク質の捕獲精製プロセス
|
US8470817B2
(en)
*
|
2009-10-26 |
2013-06-25 |
Sunesis Pharmaceuticals, Inc. |
Compounds and methods for treatment of cancer
|
US20110129858A1
(en)
*
|
2009-11-27 |
2011-06-02 |
Changhua Christian Hospital |
Prognosis Biomarker for Evaluating the Cure Level of Stroke Patient and a Method thereof
|
JP2013515080A
(ja)
|
2009-12-21 |
2013-05-02 |
アンブルックス,インコーポレイテッド |
修飾されているウシのソマトトロピンポリペプチドおよびそれらの使用
|
RS53010B
(en)
|
2009-12-31 |
2014-04-30 |
Arven Ilac Sanayi Ve Ticaret A.S. |
NEW PROCEDURE FOR PREPARATION OF G-CSF (GRANULOCITE COLONY STIMULATION FACTOR)
|
BR112012020552A2
(pt)
*
|
2010-02-19 |
2016-07-19 |
Acea Biosciences Inc |
compostos heterocíclicos e usos como agentes anticancerígenos
|
RU2573909C2
(ru)
|
2010-03-04 |
2016-01-27 |
Пфенекс Инк. |
Способ получения растворимого рекомбинантного белка интерферона без денатурирования
|
US20110223157A1
(en)
*
|
2010-03-12 |
2011-09-15 |
Schafer Peter H |
Methods for the treatment of non-hodgkin's lymphomas using lenalidomide, and gene and protein biomarkers as a predictor
|
AU2011235210B2
(en)
|
2010-04-01 |
2015-07-16 |
Pfenex Inc. |
Methods for G-CSF production in a Pseudomonas host cell
|
WO2012019168A2
(en)
*
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
EP2621519B1
(en)
|
2010-09-28 |
2017-06-28 |
Aegerion Pharmaceuticals, Inc. |
Leptin-abd fusion polypeptides with enhanced duration of action
|
US20140031325A1
(en)
|
2010-12-06 |
2014-01-30 |
Celgene Corporation |
Combination therapy with lenalidomide and a cdk inhibitor for treating multiple myeloma
|
CN103338753A
(zh)
|
2011-01-31 |
2013-10-02 |
细胞基因公司 |
胞苷类似物的药物组合物及其使用方法
|
EP2683384B1
(en)
|
2011-03-11 |
2015-12-09 |
Celgene Corporation |
Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione
|
DK2683708T3
(da)
|
2011-03-11 |
2018-01-29 |
Celgene Corp |
Faste former af 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidin-2,6-dion og farmaceutiske sammensætninger og anvendelser deraf
|
MX353482B
(es)
|
2011-04-29 |
2018-01-16 |
Celgene Corp |
Metodos para el tratamiento del cancer y enfermedades inflamatorias utilizando cereblon como predictor.
|
US9320777B2
(en)
|
2011-05-13 |
2016-04-26 |
Bolder Biotechnology, Inc. |
Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
|
US11707408B2
(en)
|
2011-10-25 |
2023-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US10350139B2
(en)
|
2011-10-25 |
2019-07-16 |
Corning Incorporated |
Pharmaceutical glass packaging assuring pharmaceutical sterility
|
US9125884B2
(en)
|
2011-11-01 |
2015-09-08 |
Celgene Corporation |
Methods for treating cancers using oral formulations of cytidine analogs
|
US8889630B2
(en)
|
2011-12-23 |
2014-11-18 |
Carlos Lopez |
Method for hair regrowth using Granulocyte-Colony Stimulating Factor
|
HUP1200172A2
(en)
*
|
2012-03-19 |
2013-10-28 |
Richter Gedeon Nyrt |
Methods for refolding g-csf from inclusion bodies
|
HUP1200171A1
(hu)
|
2012-03-19 |
2013-09-30 |
Richter Gedeon Nyrt |
Módszerek polipeptidek elõállítására
|
WO2013155347A1
(en)
|
2012-04-11 |
2013-10-17 |
Izumi Raquel |
Bruton's tyrosine kinase inhibitors for hematopoietic mobilization
|
EP2841084B1
(en)
|
2012-04-24 |
2018-05-30 |
Biokine Therapeutics Ltd. |
Cxcr4 antagonist peptide for use in the treatment of large cell lung cancer
|
CA3136093A1
(en)
|
2012-06-29 |
2014-01-03 |
Celgene Corporation |
Methods for determining drug efficacy using cereblon-associated proteins
|
US9732144B2
(en)
|
2012-07-05 |
2017-08-15 |
Ohio State Innovation Foundation |
Infectious bursal disease (IBDV) vaccine compositions
|
EP2879710B1
(en)
|
2012-08-03 |
2019-11-13 |
Dana-Farber Cancer Institute, Inc. |
Medical uses of agents that modulate immune cell activation and corresponding screening methods
|
JP6347782B2
(ja)
|
2012-08-09 |
2018-06-27 |
セルジーン コーポレイション |
3−(4−((4−(モルホリノメチル)ベンジル)オキシ)−1−オキソイソインドリン−2−イル)ピペリジン−2,6−ジオンを使用する癌の治療方法
|
ES2885769T3
(es)
|
2012-08-09 |
2021-12-15 |
Celgene Corp |
Una forma sólida de clorhidrato de (s)-3-(4-((4-morpholinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidina-2,6-diona
|
US9587281B2
(en)
|
2012-08-14 |
2017-03-07 |
Celgene Corporation |
Cereblon isoforms and their use as biomarkers for therapeutic treatment
|
SG11201501653RA
(en)
|
2012-09-10 |
2015-04-29 |
Celgene Corp |
Methods for the treatment of locally advanced breast cancer
|
US9968627B2
(en)
|
2013-03-26 |
2018-05-15 |
Celgene Corporation |
Solid forms comprising 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and a coformer, compositions and methods of use thereof
|
WO2014165482A1
(en)
|
2013-04-02 |
2014-10-09 |
Celgene Corporation |
Methods and compositions using 4-amino-2-(2,6-dioxo-piperidine-3-yl)-isoindoline-1,3-dione for treatment and management of central nervous system cancers
|
US9717649B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700486B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700485B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9849066B2
(en)
|
2013-04-24 |
2017-12-26 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9839579B2
(en)
|
2013-04-24 |
2017-12-12 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9713572B2
(en)
|
2013-04-24 |
2017-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707155B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707154B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9603775B2
(en)
|
2013-04-24 |
2017-03-28 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707153B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9717648B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
EP3004877A4
(en)
|
2013-06-06 |
2017-04-19 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms
|
EP2815749A1
(en)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
|
EP3049442A4
(en)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
WO2015057992A1
(en)
|
2013-10-16 |
2015-04-23 |
Izumi Raquel |
Btk inhibitors for hematopoietic mobilization
|
US20160296632A1
(en)
|
2013-11-13 |
2016-10-13 |
Aequus Biopharma, Inc. |
Engineered glycoproteins and uses thereof
|
EP3094736A4
(en)
|
2014-01-14 |
2017-10-25 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
|
US20150359810A1
(en)
|
2014-06-17 |
2015-12-17 |
Celgene Corporation |
Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine
|
JP6640126B2
(ja)
|
2014-06-27 |
2020-02-05 |
セルジーン コーポレイション |
セレブロン及び他のe3ユビキチンリガーゼの立体構造の変化を誘導するための組成物及び方法
|
US9499514B2
(en)
|
2014-07-11 |
2016-11-22 |
Celgene Corporation |
Antiproliferative compounds and methods of use thereof
|
SI3182996T1
(sl)
|
2014-08-22 |
2023-04-28 |
Celgene Corporation |
Postopki zdravljenja multiplega mieloma z imunomodulatornimi spojinami v kombinaciji s protitelesi
|
US20180086808A1
(en)
|
2015-03-16 |
2018-03-29 |
Arven Ilac Sanayi Ve Ticaret A.S. |
A process for preparing g-csf (granulocyte colony stimulating factor)
|
JP6525171B2
(ja)
|
2015-04-13 |
2019-06-05 |
国立研究開発法人産業技術総合研究所 |
環状化サイトカイン及びその製法
|
HUE065109T2
(hu)
|
2015-06-26 |
2024-05-28 |
Celgene Corp |
Eljárások Kaposi-szarkóma vagy KSHV-indukált limfóma kezelésére immunomodulátor vegyületek alkalmazásával, valamint biomarkerek alkalmazása
|
US10786547B2
(en)
|
2015-07-16 |
2020-09-29 |
Biokine Therapeutics Ltd. |
Compositions, articles of manufacture and methods for treating cancer
|
CN108348593B
(zh)
|
2015-08-31 |
2022-08-16 |
泰克诺瓦克斯股份有限公司 |
基于人呼吸道合胞病毒(hrsv)病毒样颗粒(vlps)的疫苗
|
US11229683B2
(en)
|
2015-09-18 |
2022-01-25 |
Bolder Biotechnology, Inc. |
Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposure
|
WO2017066561A2
(en)
|
2015-10-16 |
2017-04-20 |
President And Fellows Of Harvard College |
Regulatory t cell pd-1 modulation for regulating t cell effector immune responses
|
CA2998578A1
(en)
|
2015-10-19 |
2017-04-27 |
Sandoz Ag |
Improved coding sequence for human g-csf
|
EP3365359A1
(en)
|
2015-10-19 |
2018-08-29 |
Sandoz AG |
Method for producing a recombinant protein with reduced impurities
|
CN109069486A
(zh)
|
2015-12-14 |
2018-12-21 |
X4 制药有限公司 |
治疗癌症的方法
|
ES2907489T3
(es)
|
2015-12-14 |
2022-04-25 |
X4 Pharmaceuticals Inc |
Métodos para el tratamiento del cáncer
|
DK3393468T3
(da)
|
2015-12-22 |
2022-12-19 |
X4 Pharmaceuticals Inc |
Fremgangsmåder til behandling af en immundefektsygdom
|
WO2017117118A1
(en)
|
2015-12-28 |
2017-07-06 |
Celgene Corporation |
Compositions and methods for inducing conformational changes in cereblon and other e3 ubiquitin ligases
|
WO2017120422A1
(en)
|
2016-01-08 |
2017-07-13 |
Celgene Corporation |
Antiproliferative compounds, and their pharmaceutical compositions and uses
|
CA3010794A1
(en)
|
2016-01-08 |
2017-07-13 |
Celgene Corporation |
Solid forms of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide, and their pharmaceutical compositions and uses
|
EP3399979B9
(en)
|
2016-01-08 |
2023-10-04 |
Celgene Corporation |
Formulations of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
|
KR102033920B1
(ko)
|
2016-02-23 |
2019-10-18 |
바이오라인알엑스 리미티드 |
급성 골수성 백혈병을 치료하는 방법
|
AU2017238054B2
(en)
|
2016-03-21 |
2023-10-19 |
Dana-Farber Cancer Institute, Inc. |
T-cell exhaustion state-specific gene expression regulators and uses thereof
|
EA039392B1
(ru)
|
2016-04-01 |
2022-01-21 |
СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи |
Способ лечения рака с применением замещенного аминопуринового соединения
|
MX2018011970A
(es)
|
2016-04-01 |
2019-05-20 |
Signal Pharm Llc |
Formas sólidas de (1s,4s)-4-(2-(((3s,4r)-3-fluorotetrahidro-2h-pir an-4-il)amino)-8-((2,4,6-triclorofenilo)amino)-9h-purin-9-il)-1-m etilciclohexano-1-carboxamida y métodos para utilizarlas.
|
US11337969B2
(en)
|
2016-04-08 |
2022-05-24 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
CA3020426A1
(en)
|
2016-04-13 |
2017-10-19 |
Synthetic Genomics, Inc. |
Recombinant arterivirus replicon systems and uses thereof
|
CA3027495A1
(en)
|
2016-06-21 |
2017-12-28 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
CN109641838A
(zh)
|
2016-06-21 |
2019-04-16 |
X4 制药有限公司 |
Cxcr4抑制剂及其用途
|
CN116554168A
(zh)
|
2016-06-21 |
2023-08-08 |
X4 制药有限公司 |
Cxcr4抑制剂及其用途
|
WO2018013689A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, method of preparation and use thereof
|
WO2018013693A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and cocrystals comprising 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione compositions and methods of use thereof
|
AU2017347725B2
(en)
|
2016-10-17 |
2024-01-04 |
Janssen Pharmaceuticals, Inc. |
Recombinant virus replicon systems and uses thereof
|
AU2017372731B2
(en)
|
2016-12-05 |
2024-05-23 |
Janssen Pharmaceuticals, Inc. |
Compositions and methods for enhancing gene expression
|
WO2018165142A1
(en)
|
2017-03-07 |
2018-09-13 |
Celgene Corporation |
Solid forms of 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses
|
EP4331679A3
(en)
|
2017-06-21 |
2024-04-03 |
Shy Therapeutics LLC |
Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
SG11201913008TA
(en)
|
2017-06-30 |
2020-01-30 |
Celgene Corp |
Compositions and methods of use of 2-(4-chlorophenyl)-n-((2-(2,6-doxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl) -2,2-difluoroacetamide
|
KR20200061363A
(ko)
|
2017-10-04 |
2020-06-02 |
셀진 코포레이션 |
시스-4-[2-{[(3s,4r)-3-플루오로옥산-4-일]아미노}-8-(2,4,6-트리클로로아닐리노)-9h-퓨린-9-일]-1-메틸사이클로헥산-1-카르복스아미드의 제조 공정
|
BR122022005778B1
(pt)
|
2017-10-04 |
2024-01-09 |
Celgene Corporation |
Cápsula compreendendo cis-4-[2-{[(3s,4r)-3-fluoro-oxan-4-il]amino}-8-(2,4,6-tricloroanilino)-9h-purin-9-il]-1-metilciclohexano-1-carboxamida
|
KR102461760B1
(ko)
*
|
2017-10-11 |
2022-10-31 |
엘랑코 유에스 인코포레이티드 |
돼지 g-csf 변이체 및 그 용도
|
MX2020004836A
(es)
|
2017-11-06 |
2020-10-16 |
Rapt Therapeutics Inc |
Agentes anticancerígenos.
|
US11020476B2
(en)
|
2017-12-19 |
2021-06-01 |
Janssen Sciences Ireland Unlimited Company |
Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV)
|
EA202091513A1
(ru)
|
2017-12-19 |
2020-09-09 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Вакцины против вируса гепатита b (hbv) и их применение
|
EA202091517A1
(ru)
|
2017-12-19 |
2020-11-03 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Способы и устройство для доставки вакцин против вируса гепатита b (hbv)
|
US11083786B2
(en)
|
2018-01-19 |
2021-08-10 |
Janssen Pharmaceuticals, Inc. |
Induce and enhance immune responses using recombinant replicon systems
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
JP7407461B2
(ja)
|
2018-12-19 |
2024-01-04 |
シャイ・セラピューティクス・エルエルシー |
がん、炎症性疾患、ras病、及び線維性疾患の処置のためのrasスーパーファミリーと相互作用する化合物
|
WO2020234742A1
(en)
|
2019-05-20 |
2020-11-26 |
Lupin Limited |
Granulocyte colony stimulating factor purification
|
WO2021091946A1
(en)
|
2019-11-05 |
2021-05-14 |
Celgene Corporation |
Combination therapy with 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl)-2,2-difluoroacetamide
|
US20230227466A1
(en)
|
2020-06-18 |
2023-07-20 |
Shy Therapeutics, Llc |
Substituted thienopyrimidines that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
TW202406901A
(zh)
|
2022-04-14 |
2024-02-16 |
美商必治妥美雅史谷比公司 |
新穎gspt1化合物以及新穎化合物之使用方法
|
WO2024064646A1
(en)
|
2022-09-20 |
2024-03-28 |
Celgene Corporation |
Salts and solid forms of (s)- or racemic 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and methods of using the same
|