JPS6437291A - Human cytochrome c gene and use thereof - Google Patents

Human cytochrome c gene and use thereof

Info

Publication number
JPS6437291A
JPS6437291A JP62194216A JP19421687A JPS6437291A JP S6437291 A JPS6437291 A JP S6437291A JP 62194216 A JP62194216 A JP 62194216A JP 19421687 A JP19421687 A JP 19421687A JP S6437291 A JPS6437291 A JP S6437291A
Authority
JP
Japan
Prior art keywords
human cytochrome
dna
prepared
human
dna sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62194216A
Other languages
Japanese (ja)
Inventor
Yoshikazu Tanaka
Toshihiko Ashikari
Yuji Shibano
Hajime Yoshizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Priority to JP62194216A priority Critical patent/JPS6437291A/en
Publication of JPS6437291A publication Critical patent/JPS6437291A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/80—Cytochromes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PURPOSE:To provide the titled gene separated by a gene recombination DNA technique and useful for the microbial production of recombinant human cytochrome C. CONSTITUTION:A DNA sequence coding an amino acid sequence of human cytochrome C protein expressed by the formula (the underlined TTG may be TTA). A host cell (e.g. yeast) is transformed with a plasmid containing said DNA sequence and the obtained recombinant host cell is cultured. A recombinant human cytochrome C free from acetylated N-terminal is separated from the cultured bacterial cell and, as necessary, the N-terminal is acetylated to obtain a human cytochrome C useful as a tissue respiration activator. Said DNA sequence can be prepared by conventional process from the whole DNA prepared from a human tissue. As an alternative, it can be prepared by screening a human tissue-originated chromosome DNA library using a 3'-nondecoded region of human cytochrome C cDNA as a probe.
JP62194216A 1987-08-03 1987-08-03 Human cytochrome c gene and use thereof Pending JPS6437291A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62194216A JPS6437291A (en) 1987-08-03 1987-08-03 Human cytochrome c gene and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62194216A JPS6437291A (en) 1987-08-03 1987-08-03 Human cytochrome c gene and use thereof

Publications (1)

Publication Number Publication Date
JPS6437291A true JPS6437291A (en) 1989-02-07

Family

ID=16320885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62194216A Pending JPS6437291A (en) 1987-08-03 1987-08-03 Human cytochrome c gene and use thereof

Country Status (1)

Country Link
JP (1) JPS6437291A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04199201A (en) * 1990-10-23 1992-07-20 Mitsubishi Electric Corp Safety device for servo control mechanism
US5459046A (en) * 1989-02-28 1995-10-17 Suntory Limited Cytochrome C gene derived from hydrogen bacterium
US5773947A (en) * 1994-05-11 1998-06-30 Asmo Co., Ltd. Position detector and position control method for a moving body
US6054822A (en) * 1993-11-01 2000-04-25 Mitsubishi Denki Kabushiki Kaisha Method of detecting overload state of on-vehicle electric motor and apparatus thereof
CN103977381A (en) * 2014-05-22 2014-08-13 刘建国 Drug for treating carbon monoxide poisoning sequelae

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459046A (en) * 1989-02-28 1995-10-17 Suntory Limited Cytochrome C gene derived from hydrogen bacterium
JPH04199201A (en) * 1990-10-23 1992-07-20 Mitsubishi Electric Corp Safety device for servo control mechanism
US6054822A (en) * 1993-11-01 2000-04-25 Mitsubishi Denki Kabushiki Kaisha Method of detecting overload state of on-vehicle electric motor and apparatus thereof
US5773947A (en) * 1994-05-11 1998-06-30 Asmo Co., Ltd. Position detector and position control method for a moving body
CN103977381A (en) * 2014-05-22 2014-08-13 刘建国 Drug for treating carbon monoxide poisoning sequelae

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