JPS6437291A - Human cytochrome c gene and use thereof - Google Patents
Human cytochrome c gene and use thereofInfo
- Publication number
- JPS6437291A JPS6437291A JP62194216A JP19421687A JPS6437291A JP S6437291 A JPS6437291 A JP S6437291A JP 62194216 A JP62194216 A JP 62194216A JP 19421687 A JP19421687 A JP 19421687A JP S6437291 A JPS6437291 A JP S6437291A
- Authority
- JP
- Japan
- Prior art keywords
- human cytochrome
- dna
- prepared
- human
- dna sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/80—Cytochromes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PURPOSE:To provide the titled gene separated by a gene recombination DNA technique and useful for the microbial production of recombinant human cytochrome C. CONSTITUTION:A DNA sequence coding an amino acid sequence of human cytochrome C protein expressed by the formula (the underlined TTG may be TTA). A host cell (e.g. yeast) is transformed with a plasmid containing said DNA sequence and the obtained recombinant host cell is cultured. A recombinant human cytochrome C free from acetylated N-terminal is separated from the cultured bacterial cell and, as necessary, the N-terminal is acetylated to obtain a human cytochrome C useful as a tissue respiration activator. Said DNA sequence can be prepared by conventional process from the whole DNA prepared from a human tissue. As an alternative, it can be prepared by screening a human tissue-originated chromosome DNA library using a 3'-nondecoded region of human cytochrome C cDNA as a probe.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62194216A JPS6437291A (en) | 1987-08-03 | 1987-08-03 | Human cytochrome c gene and use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62194216A JPS6437291A (en) | 1987-08-03 | 1987-08-03 | Human cytochrome c gene and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6437291A true JPS6437291A (en) | 1989-02-07 |
Family
ID=16320885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62194216A Pending JPS6437291A (en) | 1987-08-03 | 1987-08-03 | Human cytochrome c gene and use thereof |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6437291A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04199201A (en) * | 1990-10-23 | 1992-07-20 | Mitsubishi Electric Corp | Safety device for servo control mechanism |
US5459046A (en) * | 1989-02-28 | 1995-10-17 | Suntory Limited | Cytochrome C gene derived from hydrogen bacterium |
US5773947A (en) * | 1994-05-11 | 1998-06-30 | Asmo Co., Ltd. | Position detector and position control method for a moving body |
US6054822A (en) * | 1993-11-01 | 2000-04-25 | Mitsubishi Denki Kabushiki Kaisha | Method of detecting overload state of on-vehicle electric motor and apparatus thereof |
CN103977381A (en) * | 2014-05-22 | 2014-08-13 | 刘建国 | Drug for treating carbon monoxide poisoning sequelae |
-
1987
- 1987-08-03 JP JP62194216A patent/JPS6437291A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5459046A (en) * | 1989-02-28 | 1995-10-17 | Suntory Limited | Cytochrome C gene derived from hydrogen bacterium |
JPH04199201A (en) * | 1990-10-23 | 1992-07-20 | Mitsubishi Electric Corp | Safety device for servo control mechanism |
US6054822A (en) * | 1993-11-01 | 2000-04-25 | Mitsubishi Denki Kabushiki Kaisha | Method of detecting overload state of on-vehicle electric motor and apparatus thereof |
US5773947A (en) * | 1994-05-11 | 1998-06-30 | Asmo Co., Ltd. | Position detector and position control method for a moving body |
CN103977381A (en) * | 2014-05-22 | 2014-08-13 | 刘建国 | Drug for treating carbon monoxide poisoning sequelae |
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