HUE034465T2 - Monoclonal antibodies for tumor treatment - Google Patents
Monoclonal antibodies for tumor treatment Download PDFInfo
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- HUE034465T2 HUE034465T2 HUE09711038A HUE09711038A HUE034465T2 HU E034465 T2 HUE034465 T2 HU E034465T2 HU E09711038 A HUE09711038 A HU E09711038A HU E09711038 A HUE09711038 A HU E09711038A HU E034465 T2 HUE034465 T2 HU E034465T2
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Landscapes
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| US7981420B2 (en) | 2000-12-22 | 2011-07-19 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Therapeutic use of antibodies directed against repulsive guidance molecule (RGM) |
| CN101277974A (zh) | 2005-09-30 | 2008-10-01 | 阿伯特有限及两合公司 | 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途 |
| EP2033971A1 (de) * | 2007-09-06 | 2009-03-11 | Abbott GmbH & Co. KG | Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung |
| EP3153526B1 (en) | 2008-01-31 | 2020-09-23 | INSERM - Institut National de la Santé et de la Recherche Médicale | Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity |
| US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| CN102203132A (zh) | 2008-08-25 | 2011-09-28 | 安普利穆尼股份有限公司 | Pd-1拮抗剂的组合物和使用方法 |
| MX2012006560A (es) * | 2009-12-08 | 2012-10-05 | Abbott Gmbh & Co Kg | Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal. |
| CN102675460B (zh) * | 2011-02-28 | 2015-08-19 | 珠海市丽珠单抗生物技术有限公司 | 抗肿瘤坏死因子α的人源化抗体 |
| MX338353B (es) * | 2011-04-20 | 2016-04-13 | Medimmune Llc | Anticuerpos y otras moleculas que se unen a b7 - h1 y pd - 1. |
| CA2840018C (en) | 2011-07-24 | 2019-07-16 | Curetech Ltd. | Variants of humanized immunomodulatory monoclonal antibodies |
| AR087405A1 (es) * | 2011-08-01 | 2014-03-19 | Genentech Inc | Metodos para tratar el cancer por el uso de antagonistas de union al eje pd-1 e inhibidores de mek |
| CN107880124B (zh) | 2012-01-27 | 2021-08-13 | 艾伯维德国有限责任两合公司 | 用于诊断和治疗与神经突变性相关的疾病的组合物和方法 |
| RU2689760C2 (ru) | 2012-05-31 | 2019-05-30 | Дженентек, Инк. | Способы лечения рака с применением антагонистов аксиального связывания pd-1 и vegf антагонистов |
| WO2014031174A1 (en) | 2012-08-24 | 2014-02-27 | The Regents Of The University Of California | Antibodies and vaccines for use in treating ror1 cancers and inhibiting metastasis |
| AU2013337277B2 (en) | 2012-11-05 | 2018-03-08 | Foundation Medicine, Inc. | Novel NTRK1 fusion molecules and uses thereof |
| CA2890346A1 (en) | 2012-11-05 | 2014-05-08 | Foundation Medicine, Inc. | Novel fusion molecules and uses thereof |
| LT2925350T (lt) | 2012-12-03 | 2019-04-10 | Bristol-Myers Squibb Company | Imunomoduliuojančių fc sulietų baltymų priešvėžinio aktyvumo stiprinimas |
| MX2015007446A (es) | 2012-12-12 | 2015-12-07 | Vasculox Inc | Anticuerpos terapeuticos para cd47. |
| US9221908B2 (en) | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| EP3939614A1 (en) | 2013-01-18 | 2022-01-19 | Foundation Medicine, Inc. | Methods of treating cholangiocarcinoma |
| UY35340A (es) | 2013-02-20 | 2014-09-30 | Novartis Ag | Marcaje efectivo de leucemia humana usando células diseñadas con un receptor quimérico de antígeno anti-cd123 |
| DK2958943T3 (da) | 2013-02-20 | 2019-12-09 | Univ Pennsylvania | Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor |
| LT2964638T (lt) | 2013-03-06 | 2017-12-27 | Astrazeneca Ab | Epidermio augimo faktoriaus receptoriaus aktyvinančių mutacijų formų chinazolino inhibitoriai |
| TWI654206B (zh) | 2013-03-16 | 2019-03-21 | 諾華公司 | 使用人類化抗-cd19嵌合抗原受體治療癌症 |
| EA201591931A1 (ru) | 2013-04-09 | 2016-05-31 | Ликсте Байотекнолоджи, Инк. | Композиции оксабициклогептанов и оксабициклогептенов |
| MY183503A (en) | 2013-07-16 | 2021-02-23 | Genentech Inc | Method of treating cancer using pd-1 axis binding antagonists and tigit inhibitors |
| ES2760249T3 (es) | 2013-08-08 | 2020-05-13 | Cytune Pharma | Composición farmacéutica combinada |
| HUE057598T2 (hu) | 2013-08-08 | 2022-05-28 | Cytune Pharma | IL-15 és IL-15R-alfa sushi domén alapú modulokinek |
| WO2015048312A1 (en) | 2013-09-26 | 2015-04-02 | Costim Pharmaceuticals Inc. | Methods for treating hematologic cancers |
| WO2015066413A1 (en) | 2013-11-01 | 2015-05-07 | Novartis Ag | Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections |
| US9580504B1 (en) * | 2013-11-07 | 2017-02-28 | Curetech Ltd. | Pidilizumab monoclonal antibody therapy following stem cell transplantation |
| WO2015073644A1 (en) | 2013-11-13 | 2015-05-21 | Novartis Ag | Mtor inhibitors for enhancing the immune response |
| US20150140125A1 (en) * | 2013-11-19 | 2015-05-21 | Life Plus, LLC | Synergistic cancer therapy drug combinations |
| US20150190506A1 (en) | 2013-12-17 | 2015-07-09 | Genentech, Inc. | Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists |
| EP3647324A1 (en) | 2013-12-17 | 2020-05-06 | F. Hoffmann-La Roche AG | Methods of treating cancers using pd-1 axis binding antagonists and taxanes |
| EP3083690A1 (en) | 2013-12-17 | 2016-10-26 | F.Hoffmann-La Roche Ag | Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody |
| US10640569B2 (en) | 2013-12-19 | 2020-05-05 | Novartis Ag | Human mesothelin chimeric antigen receptors and uses thereof |
| JO3517B1 (ar) | 2014-01-17 | 2020-07-05 | Novartis Ag | ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2 |
| TWI680138B (zh) | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗pd-l1之人類抗體 |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對pd-1的人類抗體 |
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|---|---|
| CN101970499A (zh) | 2011-02-09 |
| BRPI0907718A2 (pt) | 2017-06-13 |
| US20140302032A1 (en) | 2014-10-09 |
| PT2242773T (pt) | 2017-09-15 |
| CA2715166A1 (en) | 2009-08-20 |
| ES2639857T3 (es) | 2017-10-30 |
| PL2242773T3 (pl) | 2017-11-30 |
| AU2009213738B2 (en) | 2015-01-22 |
| RU2014134177A (ru) | 2016-03-20 |
| HK1209653A1 (en) | 2016-04-08 |
| US8747847B2 (en) | 2014-06-10 |
| EP2242773B1 (en) | 2017-06-14 |
| CN104548091A (zh) | 2015-04-29 |
| CN101970499B (zh) | 2014-12-31 |
| MX2010008786A (es) | 2010-12-01 |
| RU2531758C2 (ru) | 2014-10-27 |
| RU2010135585A (ru) | 2012-03-20 |
| US20110117085A1 (en) | 2011-05-19 |
| JP5911539B2 (ja) | 2016-04-27 |
| JP2015038080A (ja) | 2015-02-26 |
| WO2009101611A1 (en) | 2009-08-20 |
| EP2242773A1 (en) | 2010-10-27 |
| US9309308B2 (en) | 2016-04-12 |
| CA2715166C (en) | 2017-05-16 |
| AU2009213738A1 (en) | 2009-08-20 |
| JP2011512332A (ja) | 2011-04-21 |
| DK2242773T3 (en) | 2017-09-25 |
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