HK1140107A1 - Inhibitors of bruton's tyrosine kinase bruton - Google Patents

Inhibitors of bruton's tyrosine kinase bruton

Info

Publication number
HK1140107A1
HK1140107A1 HK10106827.4A HK10106827A HK1140107A1 HK 1140107 A1 HK1140107 A1 HK 1140107A1 HK 10106827 A HK10106827 A HK 10106827A HK 1140107 A1 HK1140107 A1 HK 1140107A1
Authority
HK
Hong Kong
Prior art keywords
bruton
inhibitors
disclosed
tyrosine kinase
compounds
Prior art date
Application number
HK10106827.4A
Other languages
English (en)
Inventor
Lee Honigberg
Erik Verner
Zhengying Pan
Original Assignee
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1140107(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Publication of HK1140107A1 publication Critical patent/HK1140107A1/xx

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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Chemical Kinetics & Catalysis (AREA)
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  • Diabetes (AREA)
  • Endocrinology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
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  • Molecular Biology (AREA)
  • Mycology (AREA)
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  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
HK10106827.4A 2006-09-22 2009-09-14 Inhibitors of bruton's tyrosine kinase bruton HK1140107A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US82859006P 2006-10-06 2006-10-06
HK09108393.7A HK1129274A1 (zh) 2006-09-22 2009-09-14 酪氨酸激酶抑制劑

Publications (1)

Publication Number Publication Date
HK1140107A1 true HK1140107A1 (en) 2010-10-08

Family

ID=39225888

Family Applications (3)

Application Number Title Priority Date Filing Date
HK09108393.7A HK1129274A1 (zh) 2006-09-22 2009-09-14 酪氨酸激酶抑制劑
HK10106827.4A HK1140107A1 (en) 2006-09-22 2009-09-14 Inhibitors of bruton's tyrosine kinase bruton
HK13104973.8A HK1178144A1 (en) 2006-09-22 2013-04-24 Inhibitors of brutons tyrosine kinase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK09108393.7A HK1129274A1 (zh) 2006-09-22 2009-09-14 酪氨酸激酶抑制劑

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK13104973.8A HK1178144A1 (en) 2006-09-22 2013-04-24 Inhibitors of brutons tyrosine kinase

Country Status (28)

Country Link
US (48) US7514444B2 (fr)
EP (11) EP2526771B1 (fr)
JP (4) JP4934197B2 (fr)
KR (4) KR101315610B1 (fr)
CN (4) CN102746305B (fr)
AT (1) ATE531263T1 (fr)
AU (2) AU2006348662B8 (fr)
BR (2) BRPI0622277A2 (fr)
CA (3) CA3180977A1 (fr)
CY (11) CY1112513T1 (fr)
DK (7) DK2201840T3 (fr)
EA (3) EA018573B1 (fr)
ES (8) ES2584331T3 (fr)
FR (1) FR15C0029I2 (fr)
HK (3) HK1129274A1 (fr)
HU (10) HUE033182T2 (fr)
IL (1) IL197550A0 (fr)
LT (7) LT2530083T (fr)
LU (3) LU92692I2 (fr)
MX (3) MX2009003122A (fr)
NL (1) NL300728I1 (fr)
NZ (3) NZ601278A (fr)
PL (8) PL2529621T3 (fr)
PT (7) PT2530083T (fr)
SG (2) SG10201503235VA (fr)
SI (8) SI2530083T1 (fr)
WO (1) WO2008039218A2 (fr)
ZA (4) ZA200901784B (fr)

Families Citing this family (521)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1740591T3 (da) 2004-04-02 2009-10-26 Osi Pharm Inc Heterobicykliske proteinkinaseinhibitorer substitueret med en 6,6-biocyclisk ring
WO2007002093A2 (fr) * 2005-06-21 2007-01-04 Infinity Discovery, Inc. Formulations d'ansamycine et leurs procedes d'utilisation
WO2007136790A2 (fr) * 2006-05-18 2007-11-29 Mannkind Corporation Inhibiteurs de kinases intracellulaires
BRPI0714963A2 (pt) * 2006-08-16 2013-07-30 Novartis Ag processo de fabricaÇço de dispersÕes sàlidas de compostos terapÊuticos altamente cristalinos
SI2530083T1 (sl) * 2006-09-22 2016-09-30 Pharmacyclics Llc Inhibitorji Bruton tirozin kinaze
CA2668286C (fr) * 2006-11-03 2014-09-16 Pharmacyclics, Inc. Sonde d'activite de la tyrosine kinase de bruton et son procede d'utilisation
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