ES2896755T3 - Composiciones que comprenden polinucleótidos sintéticos que codifican proteínas relacionadas con CRISPR y ARNsg sintéticos y procedimientos de uso - Google Patents
Composiciones que comprenden polinucleótidos sintéticos que codifican proteínas relacionadas con CRISPR y ARNsg sintéticos y procedimientos de uso Download PDFInfo
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- ES2896755T3 ES2896755T3 ES14823392T ES14823392T ES2896755T3 ES 2896755 T3 ES2896755 T3 ES 2896755T3 ES 14823392 T ES14823392 T ES 14823392T ES 14823392 T ES14823392 T ES 14823392T ES 2896755 T3 ES2896755 T3 ES 2896755T3
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- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| PCT/US2014/046434 WO2015006747A2 (en) | 2013-07-11 | 2014-07-11 | Compositions comprising synthetic polynucleotides encoding crispr related proteins and synthetic sgrnas and methods of use. |
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| WO2012075040A2 (en) | 2010-11-30 | 2012-06-07 | Shire Human Genetic Therapies, Inc. | mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES |
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| DK3336082T3 (da) | 2011-06-08 | 2020-04-27 | Translate Bio Inc | Spaltelige lipider |
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| EP2734621B1 (en) | 2011-07-22 | 2019-09-04 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
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| EP3019619A4 (en) | 2017-01-11 |
| RS62529B1 (sr) | 2021-11-30 |
| JP2016523564A (ja) | 2016-08-12 |
| WO2015006747A2 (en) | 2015-01-15 |
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