BRPI0511321B8 - moduladores de transportadores de cassete de ligação de atp, composição farmacêutica e seus usos - Google Patents

moduladores de transportadores de cassete de ligação de atp, composição farmacêutica e seus usos

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Publication number
BRPI0511321B8
BRPI0511321B8 BRPI0511321A BRPI0511321A BRPI0511321B8 BR PI0511321 B8 BRPI0511321 B8 BR PI0511321B8 BR PI0511321 A BRPI0511321 A BR PI0511321A BR PI0511321 A BRPI0511321 A BR PI0511321A BR PI0511321 B8 BRPI0511321 B8 BR PI0511321B8
Authority
BR
Brazil
Prior art keywords
atp binding
binding cassette
modulators
pharmaceutical composition
cassette carrier
Prior art date
Application number
BRPI0511321A
Other languages
English (en)
Portuguese (pt)
Inventor
R Hazlewood Anna
K Singh Ashvani
F Van Goor Frederick
Mccartney Jason
Zhou Jinglan
d j grootenhuis Peter
S Hadida Ruah Sarah
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35429349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0511321(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority to BR122018075478A priority Critical patent/BR122018075478B8/pt
Publication of BRPI0511321A publication Critical patent/BRPI0511321A/pt
Publication of BRPI0511321B1 publication Critical patent/BRPI0511321B1/pt
Publication of BRPI0511321B8 publication Critical patent/BRPI0511321B8/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
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CA2545719A1 (en) * 2003-11-14 2005-06-02 Vertex Pharmaceuticals Incorporated Thiazoles and oxazoles useful as modulators of atp-binding cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US20140343098A1 (en) * 2004-06-24 2014-11-20 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
PL2489659T3 (pl) * 2004-06-24 2018-06-29 Vertex Pharma Modulatory transporterów posiadających kasetę wiążącą atp
US8088928B2 (en) * 2005-08-04 2012-01-03 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
US8093401B2 (en) * 2005-08-04 2012-01-10 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
US7855289B2 (en) * 2005-08-04 2010-12-21 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
AU2006278504B2 (en) 2005-08-04 2013-01-17 Sirtris Pharmaceuticals, Inc. Imidazopyridine derivatives as sirtuin modulating agents
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EP2532650A3 (en) 2013-11-06
RS56873B1 (sr) 2018-04-30
IL221828A0 (en) 2012-10-31
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PL1773816T3 (pl) 2015-06-30
MX341797B (es) 2016-09-02
MX365890B (es) 2019-06-19
US20150065487A1 (en) 2015-03-05
PT2489659T (pt) 2018-03-07
JP2017061565A (ja) 2017-03-30
HUE036512T2 (hu) 2018-07-30
JP5654979B2 (ja) 2015-01-14
US20150031722A1 (en) 2015-01-29
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ME02970B (me) 2018-07-20
CN103641765A (zh) 2014-03-19
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IL257540B (en) 2020-04-30
US10662192B2 (en) 2020-05-26
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US8324242B2 (en) 2012-12-04
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HK1152707A1 (en) 2012-03-09
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US8741925B2 (en) 2014-06-03
US20140155431A1 (en) 2014-06-05
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EP2489659B1 (en) 2017-12-13
BRPI0511321A (pt) 2007-07-31
NZ552543A (en) 2010-09-30
US20140163011A1 (en) 2014-06-12
AU2010249302A1 (en) 2011-01-06
US8829204B2 (en) 2014-09-09
PT2502911T (pt) 2017-07-10
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LU92761I2 (en) 2016-07-02
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