CY1107966T1 - Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii - Google Patents
Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου iiInfo
- Publication number
- CY1107966T1 CY1107966T1 CY20081100543T CY081100543T CY1107966T1 CY 1107966 T1 CY1107966 T1 CY 1107966T1 CY 20081100543 T CY20081100543 T CY 20081100543T CY 081100543 T CY081100543 T CY 081100543T CY 1107966 T1 CY1107966 T1 CY 1107966T1
- Authority
- CY
- Cyprus
- Prior art keywords
- glibenclamide
- treatment
- type
- diabetes
- metformine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Στην παρούσα εφεύρεση περιγράφονται φαρμακευτικές συνθέσεις υπό την μορφή δισκίων, χορηγούμενες δια της στοματικής οδού, οι οποίες περιλαμβάνουν γλιβενκλαμίδη και μετφορμίνη ή φαρμακευτικώς αποδεκτά άλατα αυτών, ως δραστικές ουσίες, και διατηρούνται ξεχωριστά η μια από την άλλη μέσα στην ίδια σύνθεση, για την θεραπεία του σακχαρώδη διαβήτη τύπου II.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001FI000230A ITFI20010230A1 (it) | 2001-11-29 | 2001-11-29 | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
EP02791739A EP1458364B1 (en) | 2001-11-29 | 2002-11-29 | Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1107966T1 true CY1107966T1 (el) | 2013-09-04 |
Family
ID=11442301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081100543T CY1107966T1 (el) | 2001-11-29 | 2008-05-26 | Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii |
Country Status (40)
Country | Link |
---|---|
US (1) | US20050053661A1 (el) |
EP (1) | EP1458364B1 (el) |
JP (1) | JP4474162B2 (el) |
KR (1) | KR20040079898A (el) |
CN (1) | CN1596103B (el) |
AR (1) | AR037407A1 (el) |
AT (1) | ATE387190T1 (el) |
AU (1) | AU2002358061B2 (el) |
BR (1) | BR0214403A (el) |
CA (1) | CA2466677A1 (el) |
CO (1) | CO5590906A2 (el) |
CY (1) | CY1107966T1 (el) |
DE (1) | DE60225331T2 (el) |
DK (1) | DK1458364T3 (el) |
EA (1) | EA006766B1 (el) |
EG (1) | EG24124A (el) |
ES (1) | ES2302862T3 (el) |
HK (1) | HK1069974A1 (el) |
HN (1) | HN2002000341A (el) |
HR (1) | HRP20040501A2 (el) |
HU (1) | HUP0402154A3 (el) |
IL (1) | IL162143A0 (el) |
IT (1) | ITFI20010230A1 (el) |
MA (1) | MA27087A1 (el) |
MX (1) | MXPA04004974A (el) |
MY (1) | MY141243A (el) |
NO (1) | NO20042713L (el) |
NZ (1) | NZ533779A (el) |
PA (1) | PA8559801A1 (el) |
PE (1) | PE20030580A1 (el) |
PL (1) | PL206016B1 (el) |
PT (1) | PT1458364E (el) |
RS (1) | RS50937B (el) |
SI (1) | SI1458364T1 (el) |
SV (1) | SV2004001415A (el) |
TN (1) | TNSN04095A1 (el) |
UA (1) | UA81615C2 (el) |
UY (1) | UY27549A1 (el) |
WO (1) | WO2003045355A1 (el) |
ZA (1) | ZA200404880B (el) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7964216B2 (en) * | 2001-01-12 | 2011-06-21 | Sun Pharma Advanced Research Company Limited | Spaced drug delivery system |
WO2003105809A1 (en) | 2002-06-17 | 2003-12-24 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
EP2316456B1 (en) | 2003-04-29 | 2017-06-14 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss comprising an opioid antagonist and bupropion |
UY29445A1 (es) * | 2005-03-30 | 2006-10-02 | Generex Pharm Inc | Composiciones para la transmisión transmucosa oral de la metformina |
TWI471145B (zh) * | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
TW201811315A (zh) * | 2006-11-09 | 2018-04-01 | 美商歐瑞根治療有限公司 | 層狀醫藥調配物 |
ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
CA2725930A1 (en) | 2008-05-30 | 2009-12-30 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
CA2638240C (en) | 2008-08-29 | 2010-02-02 | Alexander Macgregor | Method of treating dysglycemia and glucose excursions |
ES2762113T3 (es) | 2010-01-11 | 2020-05-22 | Nalpropion Pharmaceuticals Inc | Métodos de proporcionar terapia de pérdida de peso en pacientes con depresión mayor |
RU2483717C2 (ru) * | 2010-11-22 | 2013-06-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения диабета (варианты) |
US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
SI2661266T1 (sl) | 2011-01-07 | 2021-01-29 | Anji Pharma (Us) Llc | Terapije, na osnovi kemosenzoričnih receptorskih ligandov |
US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
MX2014008190A (es) | 2012-01-06 | 2015-02-04 | Elcelyx Therapeutics Inc | Composiciones de biguanida y métodos para tratar transtornos metabólicos. |
MX2014008189A (es) | 2012-01-06 | 2015-02-12 | Elcelyx Therapeutics Inc | Composiciones y metodos para tratar trastornos metabolicos. |
EP4104824A1 (en) | 2012-06-06 | 2022-12-21 | Nalpropion Pharmaceuticals LLC | Composition for use in a method of treating overweight and obesity in patients with high cardiovascular risk |
CN107072997A (zh) | 2014-11-11 | 2017-08-18 | 盐野义制药株式会社 | 含有对光不稳定的药物的多层片剂 |
KR101750690B1 (ko) * | 2015-10-28 | 2017-06-27 | 주식회사 종근당 | 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물 |
CN105596339A (zh) * | 2015-12-23 | 2016-05-25 | 青岛海之源智能技术有限公司 | 一种二甲双胍阿昔莫司复方组合物及制备方法 |
CN110128305A (zh) * | 2019-05-10 | 2019-08-16 | 天津大学 | 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途 |
JP2021120357A (ja) * | 2020-01-30 | 2021-08-19 | サンノーバ株式会社 | 錠剤 |
GB2599950A (en) * | 2020-10-16 | 2022-04-20 | Zentiva Ks | Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same |
CN113143940A (zh) * | 2020-12-30 | 2021-07-23 | 成都恒瑞制药有限公司 | 一种抗糖尿病药物组合物的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2347531A1 (de) * | 1973-09-21 | 1975-04-30 | Hoechst Ag | Arzneizubereitungen zur oralen diabetes-behandlung |
IT1276130B1 (it) * | 1995-11-14 | 1997-10-27 | Gentili Ist Spa | Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo |
AP1224A (en) * | 1998-03-19 | 2003-11-14 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method. |
PT974356E (pt) * | 1998-07-15 | 2004-02-27 | Merck Sante Sas | Comprimidos compreendendo uma combinacao de metformina e de glibenclamida |
US6780432B1 (en) * | 2000-05-01 | 2004-08-24 | Aeropharm Technology, Inc. | Core formulation |
US7964216B2 (en) * | 2001-01-12 | 2011-06-21 | Sun Pharma Advanced Research Company Limited | Spaced drug delivery system |
-
2001
- 2001-11-29 IT IT2001FI000230A patent/ITFI20010230A1/it unknown
-
2002
- 2002-11-22 AR ARP020104498A patent/AR037407A1/es unknown
- 2002-11-25 MY MYPI20024393A patent/MY141243A/en unknown
- 2002-11-26 UY UY27549A patent/UY27549A1/es not_active Application Discontinuation
- 2002-11-26 PE PE2002001140A patent/PE20030580A1/es not_active Application Discontinuation
- 2002-11-27 EG EG2002111281A patent/EG24124A/xx active
- 2002-11-28 SV SV2002001415A patent/SV2004001415A/es not_active Application Discontinuation
- 2002-11-29 AT AT02791739T patent/ATE387190T1/de not_active IP Right Cessation
- 2002-11-29 CA CA002466677A patent/CA2466677A1/en not_active Abandoned
- 2002-11-29 SI SI200230693T patent/SI1458364T1/sl unknown
- 2002-11-29 PL PL369851A patent/PL206016B1/pl not_active IP Right Cessation
- 2002-11-29 HU HU0402154A patent/HUP0402154A3/hu unknown
- 2002-11-29 PT PT02791739T patent/PT1458364E/pt unknown
- 2002-11-29 BR BR0214403-4A patent/BR0214403A/pt not_active IP Right Cessation
- 2002-11-29 WO PCT/EP2002/013497 patent/WO2003045355A1/en active IP Right Grant
- 2002-11-29 DK DK02791739T patent/DK1458364T3/da active
- 2002-11-29 CN CN028236920A patent/CN1596103B/zh not_active Expired - Fee Related
- 2002-11-29 US US10/497,022 patent/US20050053661A1/en not_active Abandoned
- 2002-11-29 PA PA20028559801A patent/PA8559801A1/es unknown
- 2002-11-29 UA UA20040504085A patent/UA81615C2/ru unknown
- 2002-11-29 HN HN2002000341A patent/HN2002000341A/es unknown
- 2002-11-29 AU AU2002358061A patent/AU2002358061B2/en not_active Ceased
- 2002-11-29 EP EP02791739A patent/EP1458364B1/en not_active Expired - Lifetime
- 2002-11-29 MX MXPA04004974A patent/MXPA04004974A/es active IP Right Grant
- 2002-11-29 NZ NZ533779A patent/NZ533779A/en not_active IP Right Cessation
- 2002-11-29 KR KR10-2004-7006874A patent/KR20040079898A/ko not_active Application Discontinuation
- 2002-11-29 EA EA200400664A patent/EA006766B1/ru not_active IP Right Cessation
- 2002-11-29 IL IL16214302A patent/IL162143A0/xx not_active IP Right Cessation
- 2002-11-29 JP JP2003546858A patent/JP4474162B2/ja not_active Expired - Lifetime
- 2002-11-29 DE DE60225331T patent/DE60225331T2/de not_active Expired - Lifetime
- 2002-11-29 ES ES02791739T patent/ES2302862T3/es not_active Expired - Lifetime
-
2004
- 2004-05-24 MA MA27696A patent/MA27087A1/fr unknown
- 2004-05-28 RS YUP-473/04A patent/RS50937B/sr unknown
- 2004-05-28 TN TNP2004000095A patent/TNSN04095A1/en unknown
- 2004-06-04 HR HRP20040501 patent/HRP20040501A2/hr not_active Application Discontinuation
- 2004-06-21 ZA ZA200404880A patent/ZA200404880B/en unknown
- 2004-06-28 NO NO20042713A patent/NO20042713L/no not_active Application Discontinuation
- 2004-06-29 CO CO04061363A patent/CO5590906A2/es not_active Application Discontinuation
-
2005
- 2005-03-18 HK HK05102373A patent/HK1069974A1/xx not_active IP Right Cessation
-
2008
- 2008-05-26 CY CY20081100543T patent/CY1107966T1/el unknown
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