UA81615C2 - Фармацевтическая композиция, которая содержит метформин и глибенкламид, для лечения диабета типа ii - Google Patents

Фармацевтическая композиция, которая содержит метформин и глибенкламид, для лечения диабета типа ii

Info

Publication number
UA81615C2
UA81615C2 UA20040504085A UA20040504085A UA81615C2 UA 81615 C2 UA81615 C2 UA 81615C2 UA 20040504085 A UA20040504085 A UA 20040504085A UA 20040504085 A UA20040504085 A UA 20040504085A UA 81615 C2 UA81615 C2 UA 81615C2
Authority
UA
Ukraine
Prior art keywords
glibenclamide
treatment
type
pharmaceutical compositions
diabetes mellitus
Prior art date
Application number
UA20040504085A
Other languages
English (en)
Ukrainian (uk)
Inventor
Алессандро Тосетти
Мауро Гуидуччи
Джованни Вити
Original Assignee
Menarini Int Operations Lu Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11442301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA81615(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini Int Operations Lu Sa filed Critical Menarini Int Operations Lu Sa
Publication of UA81615C2 publication Critical patent/UA81615C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Описаны фармацевтические композиции для перорального применения в форме таблеток, которые содержат как активные ингредиенты глибенкламид и метформин или их фармацевтически приемлемые соли, которые находятся в одной композиции отдельно друг от друга, для лечения сахарного диабета типа II.
UA20040504085A 2001-11-29 2002-11-29 Фармацевтическая композиция, которая содержит метформин и глибенкламид, для лечения диабета типа ii UA81615C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001FI000230A ITFI20010230A1 (it) 2001-11-29 2001-11-29 Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
PCT/EP2002/013497 WO2003045355A1 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus

Publications (1)

Publication Number Publication Date
UA81615C2 true UA81615C2 (ru) 2008-01-25

Family

ID=11442301

Family Applications (1)

Application Number Title Priority Date Filing Date
UA20040504085A UA81615C2 (ru) 2001-11-29 2002-11-29 Фармацевтическая композиция, которая содержит метформин и глибенкламид, для лечения диабета типа ii

Country Status (40)

Country Link
US (1) US20050053661A1 (ru)
EP (1) EP1458364B1 (ru)
JP (1) JP4474162B2 (ru)
KR (1) KR20040079898A (ru)
CN (1) CN1596103B (ru)
AR (1) AR037407A1 (ru)
AT (1) ATE387190T1 (ru)
AU (1) AU2002358061B2 (ru)
BR (1) BR0214403A (ru)
CA (1) CA2466677A1 (ru)
CO (1) CO5590906A2 (ru)
CY (1) CY1107966T1 (ru)
DE (1) DE60225331T2 (ru)
DK (1) DK1458364T3 (ru)
EA (1) EA006766B1 (ru)
EG (1) EG24124A (ru)
ES (1) ES2302862T3 (ru)
HK (1) HK1069974A1 (ru)
HN (1) HN2002000341A (ru)
HR (1) HRP20040501A2 (ru)
HU (1) HUP0402154A3 (ru)
IL (1) IL162143A0 (ru)
IT (1) ITFI20010230A1 (ru)
MA (1) MA27087A1 (ru)
MX (1) MXPA04004974A (ru)
MY (1) MY141243A (ru)
NO (1) NO20042713L (ru)
NZ (1) NZ533779A (ru)
PA (1) PA8559801A1 (ru)
PE (1) PE20030580A1 (ru)
PL (1) PL206016B1 (ru)
PT (1) PT1458364E (ru)
RS (1) RS50937B (ru)
SI (1) SI1458364T1 (ru)
SV (1) SV2004001415A (ru)
TN (1) TNSN04095A1 (ru)
UA (1) UA81615C2 (ru)
UY (1) UY27549A1 (ru)
WO (1) WO2003045355A1 (ru)
ZA (1) ZA200404880B (ru)

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JP4633329B2 (ja) * 2001-01-12 2011-02-16 サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド スペーストドラッグデリバリーシステム
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
ATE388698T1 (de) 2003-04-29 2008-03-15 Orexigen Therapeutics Inc Zusammensetzungen zur beeinflussung des gewichtsverlusts
UY29445A1 (es) * 2005-03-30 2006-10-02 Generex Pharm Inc Composiciones para la transmisión transmucosa oral de la metformina
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
JP2010509367A (ja) * 2006-11-09 2010-03-25 オレキシジェン・セラピューティクス・インコーポレーテッド 積層製剤
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
JP2011521973A (ja) 2008-05-30 2011-07-28 オレキシジェン・セラピューティクス・インコーポレーテッド 内臓脂肪の状態を処置するための方法
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
KR20120124423A (ko) 2010-01-11 2012-11-13 오렉시젠 세러퓨틱스 인크. 주우울증 환자들에 있어서 체중 감량 치료를 제공하는 방법
RU2483717C2 (ru) * 2010-11-22 2013-06-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения диабета (варианты)
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
EP3763419A1 (en) 2011-01-07 2021-01-13 Anji Pharma (US) LLC Chemosensory receptor ligand-based therapies
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
NZ626578A (en) 2012-01-06 2016-11-25 Elcelyx Therapeutics Inc Compositions and methods for treating metabolic disorders
JP2015503582A (ja) 2012-01-06 2015-02-02 エルセリクス セラピューティクス インコーポレイテッド ビグアナイド組成物および代謝障害を治療する方法
PT3730132T (pt) 2012-06-06 2022-08-16 Nalpropion Pharmaceuticals Llc Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular
CN107072997A (zh) 2014-11-11 2017-08-18 盐野义制药株式会社 含有对光不稳定的药物的多层片剂
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN105596339A (zh) * 2015-12-23 2016-05-25 青岛海之源智能技术有限公司 一种二甲双胍阿昔莫司复方组合物及制备方法
CN110128305A (zh) * 2019-05-10 2019-08-16 天津大学 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途
JP2021120357A (ja) * 2020-01-30 2021-08-19 サンノーバ株式会社 錠剤
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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* Cited by examiner, † Cited by third party
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DE2347531A1 (de) * 1973-09-21 1975-04-30 Hoechst Ag Arzneizubereitungen zur oralen diabetes-behandlung
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
AP1224A (en) * 1998-03-19 2003-11-14 Bristol Myers Squibb Co Biphasic controlled release delivery system for high solubility pharmaceuticals and method.
PT974356E (pt) * 1998-07-15 2004-02-27 Merck Sante Sas Comprimidos compreendendo uma combinacao de metformina e de glibenclamida
US6780432B1 (en) * 2000-05-01 2004-08-24 Aeropharm Technology, Inc. Core formulation
JP4633329B2 (ja) * 2001-01-12 2011-02-16 サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド スペーストドラッグデリバリーシステム

Also Published As

Publication number Publication date
ITFI20010230A1 (it) 2003-05-29
SI1458364T1 (sl) 2008-08-31
EP1458364B1 (en) 2008-02-27
HN2002000341A (es) 2009-12-07
HUP0402154A3 (en) 2008-04-28
SV2004001415A (es) 2004-05-07
IL162143A0 (en) 2005-11-20
PE20030580A1 (es) 2003-09-05
PT1458364E (pt) 2008-05-26
MY141243A (en) 2010-03-31
PL369851A1 (en) 2005-05-02
US20050053661A1 (en) 2005-03-10
JP2005518360A (ja) 2005-06-23
HUP0402154A2 (hu) 2005-02-28
RS47304A (en) 2006-10-27
MXPA04004974A (es) 2004-08-11
ZA200404880B (en) 2005-07-29
AU2002358061A1 (en) 2003-06-10
AR037407A1 (es) 2004-11-10
EA200400664A1 (ru) 2004-10-28
WO2003045355A1 (en) 2003-06-05
JP4474162B2 (ja) 2010-06-02
CN1596103B (zh) 2010-06-16
HK1069974A1 (en) 2005-06-10
AU2002358061B2 (en) 2007-01-11
EG24124A (en) 2008-07-07
TNSN04095A1 (en) 2006-06-01
NO20042713L (no) 2004-07-16
HRP20040501A2 (en) 2004-12-31
CO5590906A2 (es) 2005-12-30
PA8559801A1 (es) 2003-06-30
PL206016B1 (pl) 2010-06-30
DE60225331T2 (de) 2009-02-26
BR0214403A (pt) 2004-10-19
EP1458364A1 (en) 2004-09-22
CY1107966T1 (el) 2013-09-04
CN1596103A (zh) 2005-03-16
DE60225331D1 (de) 2008-04-10
MA27087A1 (fr) 2004-12-20
ES2302862T3 (es) 2008-08-01
DK1458364T3 (da) 2008-06-23
ATE387190T1 (de) 2008-03-15
KR20040079898A (ko) 2004-09-16
EA006766B1 (ru) 2006-04-28
CA2466677A1 (en) 2003-06-05
NZ533779A (en) 2007-02-23
UY27549A1 (es) 2003-06-30
RS50937B (sr) 2010-08-31

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