ATE311227T1 - Schnell-wirkende, gefrier-trocknete, orale, pharmazeutische formulierung für die behandlung von migräne - Google Patents

Schnell-wirkende, gefrier-trocknete, orale, pharmazeutische formulierung für die behandlung von migräne

Info

Publication number
ATE311227T1
ATE311227T1 AT00983475T AT00983475T ATE311227T1 AT E311227 T1 ATE311227 T1 AT E311227T1 AT 00983475 T AT00983475 T AT 00983475T AT 00983475 T AT00983475 T AT 00983475T AT E311227 T1 ATE311227 T1 AT E311227T1
Authority
AT
Austria
Prior art keywords
agents
migraine
treatment
dried
freeze
Prior art date
Application number
AT00983475T
Other languages
English (en)
Inventor
Rao Pavuluri Mana Venkateswara
Podili Khadgapathi
Original Assignee
Natco Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd filed Critical Natco Pharma Ltd
Application granted granted Critical
Publication of ATE311227T1 publication Critical patent/ATE311227T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00983475T 1999-12-01 2000-08-25 Schnell-wirkende, gefrier-trocknete, orale, pharmazeutische formulierung für die behandlung von migräne ATE311227T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1160MA1999 1999-12-01
PCT/IN2000/000078 WO2001039836A1 (en) 1999-12-01 2000-08-25 A rapid acting freeze dired oral pharmaceutical composition for treating migraine

Publications (1)

Publication Number Publication Date
ATE311227T1 true ATE311227T1 (de) 2005-12-15

Family

ID=11096788

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00983475T ATE311227T1 (de) 1999-12-01 2000-08-25 Schnell-wirkende, gefrier-trocknete, orale, pharmazeutische formulierung für die behandlung von migräne

Country Status (7)

Country Link
US (1) US20050084530A1 (de)
EP (1) EP1246668B1 (de)
AT (1) ATE311227T1 (de)
AU (1) AU2023401A (de)
CA (1) CA2392810A1 (de)
DE (1) DE60024491T2 (de)
WO (1) WO2001039836A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960007947B1 (ko) 1993-09-17 1996-06-17 엘지전자 주식회사 가라오케-콤팩트 디스크(karaoke-cd) 및 이를 이용한 오디오 제어장치
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
DE10107659B4 (de) 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
DE10136781B4 (de) * 2001-07-27 2008-03-06 Lts Lohmann Therapie-Systeme Ag Flache orale Darreichungsformen mit wirkstoffhaltigen Partikeln
US7378408B2 (en) 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
GB0129117D0 (en) * 2001-12-05 2002-01-23 Glaxo Group Ltd Pharmaceutical composition
US20050256182A1 (en) * 2004-05-11 2005-11-17 Sutter Diane E Formulations of anti-pain agents and methods of using the same
FR2881139A1 (fr) * 2005-01-26 2006-07-28 Agronomique Inst Nat Rech Composition pour la lyophilisation de proteines
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
GB0613925D0 (en) * 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
EP1891938A1 (de) * 2006-07-24 2008-02-27 Cephalon France Mündlich auflösbare hohe Dosis von einer gefriergetrockneten Dosierungsform.
US20080031949A1 (en) * 2006-07-24 2008-02-07 Cima Labs Inc. High dose orally dissolvable/disintegrable lyophilized dosage form
TWI343262B (en) * 2006-09-26 2011-06-11 Schering Corp Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
EP1980240A1 (de) * 2007-04-11 2008-10-15 Cephalon France Lyophilisierte pharmazeutische Zusammensetzungen und Verfahren zu ihrer Herstellung und Verwendung
EP1980245A1 (de) * 2007-04-11 2008-10-15 Cephalon France Gefriergetrocknete pharmazeutische Zweischicht-Zusammensetzungen sowie Methoden zur Herstellung und Verwendung derselben
US20100080829A1 (en) * 2007-04-11 2010-04-01 Cephalon France Lyophilized pharmaceutical compositions and methods of making and using same
EP2240022B1 (de) 2008-01-09 2016-12-28 Charleston Laboratories, Inc. Oxycodone und Promethazine enthaltende zweischichtige Tabletten
EP2265250A2 (de) * 2008-03-14 2010-12-29 Cephalon, Inc. Verbesserte transmukosale zusammensetzung und dosierform
EP2273880B1 (de) * 2008-04-28 2014-12-31 Zogenix, Inc. Neuartige formulierungen zur behandlung von migräne
AU2013202680C1 (en) * 2008-04-28 2016-06-23 Zogenix, Inc. Novel formulations for treatment of migraine
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
EP2480197B1 (de) 2009-09-25 2015-11-11 Dr. Reddy's Laboratories Ltd. Formulierungen mit triptanverbindungen
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
US8906949B2 (en) 2010-05-21 2014-12-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablets of zolmitriptan and process for preparing the same
US20140073678A1 (en) * 2012-09-12 2014-03-13 Monosol Rx, Llc Anti-pain and anti-nausea and/or vomiting combinatorial compositions
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
US20190224171A1 (en) * 2018-01-22 2019-07-25 Insys Development Company, Inc. Liquid rizatriptan compositions
CN115444909A (zh) * 2022-09-15 2022-12-09 山东创时代生物工程有限公司 一种提高免疫力的组合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4078065A (en) * 1974-07-04 1978-03-07 Sandoz Ltd. Organic compounds
GB8428747D0 (en) * 1984-11-14 1984-12-27 Hancock K A Products for treatment of human body
DE3626097A1 (de) * 1986-07-31 1988-02-11 Goedecke Ag Wirkstoffkombination enthaltend diltiazem und acetylsalicylsaeure
FR2631826B1 (fr) * 1988-05-27 1992-06-19 Centre Nat Rech Scient Vecteur particulaire utile notamment pour le transport de molecules a activite biologique et procede pour sa preparation
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
FR2741532B1 (fr) * 1995-11-28 1998-08-21 Bouchara Sa Nouvelles compositions pharmaceutiques a action antimigraineuse et leur mode de preparation
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
EP1017366A4 (de) * 1996-09-01 2006-03-22 Pharmos Corp Feste kopräzipitate zur verbesserten bioverfügbarkeit lipophiler substanzen

Also Published As

Publication number Publication date
WO2001039836A1 (en) 2001-06-07
AU2023401A (en) 2001-06-12
EP1246668B1 (de) 2005-11-30
DE60024491D1 (de) 2006-01-05
US20050084530A1 (en) 2005-04-21
EP1246668A1 (de) 2002-10-09
DE60024491T2 (de) 2006-08-10
CA2392810A1 (en) 2001-06-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties