AU2004241101B2 - Treatment of T-cell mediated diseases - Google Patents

Treatment of T-cell mediated diseases Download PDF

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Publication number
AU2004241101B2
AU2004241101B2 AU2004241101A AU2004241101A AU2004241101B2 AU 2004241101 B2 AU2004241101 B2 AU 2004241101B2 AU 2004241101 A AU2004241101 A AU 2004241101A AU 2004241101 A AU2004241101 A AU 2004241101A AU 2004241101 B2 AU2004241101 B2 AU 2004241101B2
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AU
Australia
Prior art keywords
side chain
amino acid
acid
group
diaminobutyric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004241101A
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English (en)
Other versions
AU2004241101A1 (en
Inventor
David Bar-Or
Raphael Bar-Or
Richard Shimonkevitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampio Pharmaceuticals Inc
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Ampio Pharmaceuticals Inc
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Filing date
Publication date
Application filed by Ampio Pharmaceuticals Inc filed Critical Ampio Pharmaceuticals Inc
Publication of AU2004241101A1 publication Critical patent/AU2004241101A1/en
Application granted granted Critical
Publication of AU2004241101B2 publication Critical patent/AU2004241101B2/en
Priority to AU2010203293A priority Critical patent/AU2010203293B2/en
Assigned to AMPIO PHARMACEUTICALS, INC. reassignment AMPIO PHARMACEUTICALS, INC. Request for Assignment Assignors: DMI BIOSCIENCES, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
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    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
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    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
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    • AHUMAN NECESSITIES
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2004241101A 2003-05-15 2004-05-14 Treatment of T-cell mediated diseases Ceased AU2004241101B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010203293A AU2010203293B2 (en) 2003-05-15 2010-07-23 Treatment of T-cell mediated diseases

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US47101703P 2003-05-15 2003-05-15
US60/471,017 2003-05-15
US48927003P 2003-07-21 2003-07-21
US60/489,270 2003-07-21
US51493003P 2003-10-27 2003-10-27
US60/514,930 2003-10-27
US51733803P 2003-11-04 2003-11-04
US60/517,338 2003-11-04
PCT/US2004/015340 WO2004103304A2 (en) 2003-05-15 2004-05-14 Treatment of t-cell mediated diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010203293A Division AU2010203293B2 (en) 2003-05-15 2010-07-23 Treatment of T-cell mediated diseases

Publications (2)

Publication Number Publication Date
AU2004241101A1 AU2004241101A1 (en) 2004-12-02
AU2004241101B2 true AU2004241101B2 (en) 2010-05-13

Family

ID=33479817

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2004241101A Ceased AU2004241101B2 (en) 2003-05-15 2004-05-14 Treatment of T-cell mediated diseases
AU2010203293A Ceased AU2010203293B2 (en) 2003-05-15 2010-07-23 Treatment of T-cell mediated diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2010203293A Ceased AU2010203293B2 (en) 2003-05-15 2010-07-23 Treatment of T-cell mediated diseases

Country Status (16)

Country Link
US (15) US7732403B2 (enExample)
EP (7) EP2517718B1 (enExample)
JP (3) JP2007500747A (enExample)
KR (5) KR20170038128A (enExample)
CN (7) CN103191410B (enExample)
AU (2) AU2004241101B2 (enExample)
CA (2) CA2523467C (enExample)
DK (1) DK2537524T3 (enExample)
ES (5) ES2572454T3 (enExample)
HK (2) HK1203056A1 (enExample)
HU (1) HUE031620T2 (enExample)
IL (3) IL171961A (enExample)
NZ (2) NZ576931A (enExample)
PL (1) PL2537524T3 (enExample)
PT (1) PT2537524T (enExample)
WO (1) WO2004103304A2 (enExample)

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