UY26231A1 - Compuestos de indazol y composiciones farmaceuticas para la inhibicion de proteina kinasa y metodo para su uso. bajo ley 17.164 - Google Patents

Compuestos de indazol y composiciones farmaceuticas para la inhibicion de proteina kinasa y metodo para su uso. bajo ley 17.164

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Publication number
UY26231A1
UY26231A1 UY26231A UY26231A UY26231A1 UY 26231 A1 UY26231 A1 UY 26231A1 UY 26231 A UY26231 A UY 26231A UY 26231 A UY26231 A UY 26231A UY 26231 A1 UY26231 A1 UY 26231A1
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UY
Uruguay
Prior art keywords
pharmaceutical compositions
compounds
inhibition
protein kinase
indazole compounds
Prior art date
Application number
UY26231A
Other languages
English (en)
Inventor
Robert Steven Kania
Steven Lee Bender
Allen J Borchardt
John F Braganza
Stephan James Cripps
Ye Hua
Michael David Johnson
Theodore Otto Johnson Jr
Hiep The Luu
Cynthia Louise Palmer
Siegfried Heinz Reich
Anna Maria Tempczyk-Russell
Min Teng
Michael David Varney
Michael Brennan Wallace
Christine Thomas
Original Assignee
Agouron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22498654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY26231(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agouron Pharma filed Critical Agouron Pharma
Publication of UY26231A1 publication Critical patent/UY26231A1/es

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P27/00—Drugs for disorders of the senses
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    • A61P27/02—Ophthalmic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describieron los compuestos de indazol que modulan y/o inhiben la actividad de ciertas quinasas de proteína. Estos compuestos y composiciones farmacéuticas que los contienen son capaces de mediar la transducción senalada de quinasa tirosina y así modulan y/o inhiben la proliferación de células superfluas. El invento es dirigido también para el uso terapéutico y fármaco de las composiciones farmacéuticas que contienen tales compuestos, y para los métodos de tratar el cáncer y otras enfermedades asociadas al angiogénisis superfluo y/o la proliferación celular, como retinopatía diabética, glaucoma neovascular, artritis reumatoidea, y soriasis, por administrar cantidades efectivas de tales compuestos.
UY26231A 1999-07-02 2000-06-30 Compuestos de indazol y composiciones farmaceuticas para la inhibicion de proteina kinasa y metodo para su uso. bajo ley 17.164 UY26231A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14213099P 1999-07-02 1999-07-02

Publications (1)

Publication Number Publication Date
UY26231A1 true UY26231A1 (es) 2001-01-31

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ID=22498654

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UY26231A UY26231A1 (es) 1999-07-02 2000-06-30 Compuestos de indazol y composiciones farmaceuticas para la inhibicion de proteina kinasa y metodo para su uso. bajo ley 17.164

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EP (2) EP1218348B1 (es)
JP (2) JP3878849B2 (es)
KR (1) KR100529639B1 (es)
CN (2) CN1137884C (es)
AP (1) AP1486A (es)
AR (2) AR035554A1 (es)
AT (1) ATE376543T1 (es)
AU (1) AU777701B2 (es)
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CA2415469A1 (en) 2000-08-09 2002-02-14 Astrazeneca Ab Quinoline derivatives having vegf inhibiting activity
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