TW201315723A - Pi-3激酶抑制劑及其用途方法 - Google Patents

Pi-3激酶抑制劑及其用途方法 Download PDF

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Publication number
TW201315723A
TW201315723A TW101150766A TW101150766A TW201315723A TW 201315723 A TW201315723 A TW 201315723A TW 101150766 A TW101150766 A TW 101150766A TW 101150766 A TW101150766 A TW 101150766A TW 201315723 A TW201315723 A TW 201315723A
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Taiwan
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substituted
unsubstituted
group
compound
hydrogen
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TW101150766A
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English (en)
Chinese (zh)
Inventor
Matthew Burger
Zhi-Jie Ni
Sabina Pecchi
Gordana Atallah
Sarah Bartullis
Kelly Frazier
Aaron Smith
Joelle Verhagen
Yanchen Zhang
Allan Wagman
Simon Ng
Keith Pfister
Daniel Poon
Alicia Louie
Teresa Pick
Paul Barsanti
Edwin Iwanowicz
Wendy Fantl
Tom Hendrickson
Mark Knapp
Hanne Merritt
Charles Voliva
Marion Wiesmann
xiao-hua Xin
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Novartis Ag
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37951939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW201315723(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TW201315723A publication Critical patent/TW201315723A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW101150766A 2006-01-20 2007-01-19 Pi-3激酶抑制劑及其用途方法 TW201315723A (zh)

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US76078906P 2006-01-20 2006-01-20

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TW201315723A true TW201315723A (zh) 2013-04-16

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TW101150766A TW201315723A (zh) 2006-01-20 2007-01-19 Pi-3激酶抑制劑及其用途方法
TW096102123A TWI385170B (zh) 2006-01-20 2007-01-19 Pi-3激酶抑制劑及其用途方法

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EP (2) EP2261223B1 (https=)
JP (1) JP5161110B2 (https=)
KR (1) KR101353829B1 (https=)
CN (1) CN101389622B (https=)
AR (2) AR059087A1 (https=)
AT (1) ATE478064T1 (https=)
AU (1) AU2007206048B2 (https=)
BR (1) BRPI0707189B1 (https=)
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DE (1) DE602007008529D1 (https=)
DK (2) DK1984350T3 (https=)
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IL (1) IL192763A (https=)
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MA (1) MA30208B1 (https=)
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PE (1) PE20071322A1 (https=)
PL (2) PL1984350T3 (https=)
PT (2) PT1984350E (https=)
RS (2) RS52928B (https=)
SI (2) SI1984350T1 (https=)
SM (1) SMP200800048B (https=)
SV (1) SV2008002984A (https=)
TN (1) TNSN08305A1 (https=)
TW (2) TW201315723A (https=)
UA (1) UA96284C2 (https=)
WO (1) WO2007084786A1 (https=)
ZA (1) ZA200806017B (https=)

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