MA40513A - Conjugués médicament-anticorps anti-cdh6 - Google Patents

Conjugués médicament-anticorps anti-cdh6

Info

Publication number
MA40513A
MA40513A MA040513A MA40513A MA40513A MA 40513 A MA40513 A MA 40513A MA 040513 A MA040513 A MA 040513A MA 40513 A MA40513 A MA 40513A MA 40513 A MA40513 A MA 40513A
Authority
MA
Morocco
Prior art keywords
drug conjugates
antibody drug
cdh6 antibody
cdh6
cancer
Prior art date
Application number
MA040513A
Other languages
English (en)
Inventor
Carl Uli Bialucha
Scott Collins
Clemens Dürr
Tiancen Hu
Mary Jo Janatpour
Matthew John Meyer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA40513A publication Critical patent/MA40513A/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
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    • A61K47/6861—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from kidney or bladder cancer cell
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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  • Urology & Nephrology (AREA)
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  • Oncology (AREA)
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  • Pregnancy & Childbirth (AREA)
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Abstract

La présente invention concerne des anticorps anti-cdh6, des fragments d'anticorps, des conjugués anticorps-médicament, et leurs utilisations pour le traitement du cancer.
MA040513A 2014-08-12 2015-08-07 Conjugués médicament-anticorps anti-cdh6 MA40513A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462036382P 2014-08-12 2014-08-12

Publications (1)

Publication Number Publication Date
MA40513A true MA40513A (fr) 2017-06-21

Family

ID=54150477

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040513A MA40513A (fr) 2014-08-12 2015-08-07 Conjugués médicament-anticorps anti-cdh6

Country Status (27)

Country Link
US (2) US9982045B2 (fr)
EP (1) EP3180360A1 (fr)
JP (1) JP2017524364A (fr)
KR (1) KR20170040249A (fr)
CN (1) CN106659790A (fr)
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EA201790334A1 (ru) 2017-06-30
EP3180360A1 (fr) 2017-06-21
WO2016024195A1 (fr) 2016-02-18
NI201700016A (es) 2017-03-08
DOP2017000045A (es) 2017-05-15
TN2016000577A1 (en) 2018-04-04
TW201613643A (en) 2016-04-16
CO2017001191A2 (es) 2017-04-28
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