AR104664A1 - Conjugados de fármacos con anticuerpos contra la cadherina 6 (anti-cdh6) - Google Patents

Conjugados de fármacos con anticuerpos contra la cadherina 6 (anti-cdh6)

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Publication number
AR104664A1
AR104664A1 ARP150102601A ARP150102601A AR104664A1 AR 104664 A1 AR104664 A1 AR 104664A1 AR P150102601 A ARP150102601 A AR P150102601A AR P150102601 A ARP150102601 A AR P150102601A AR 104664 A1 AR104664 A1 AR 104664A1
Authority
AR
Argentina
Prior art keywords
conjugates
cdh6
cadherine
drugs
antibodies against
Prior art date
Application number
ARP150102601A
Other languages
English (en)
Inventor
John Meyer Matthew
Drr Clemens
Collins Scott
Uli Bialucha Carl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR104664A1 publication Critical patent/AR104664A1/es

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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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Abstract

La presente se refiere a anticuerpos anti-CDH6, fragmentos de anticuerpos, conjugados fármaco-anticuerpo y sus usos para el tratamiento del cáncer.
ARP150102601A 2014-08-12 2015-08-12 Conjugados de fármacos con anticuerpos contra la cadherina 6 (anti-cdh6) AR104664A1 (es)

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EP3180360A1 (en) 2017-06-21
PH12017500002A1 (en) 2017-05-15
BR112017001588A2 (pt) 2017-11-21
CO2017001191A2 (es) 2017-04-28
ECSP17011657A (es) 2018-03-31
US20170224836A1 (en) 2017-08-10
MA40513A (fr) 2017-06-21
US10238748B2 (en) 2019-03-26
TW201613643A (en) 2016-04-16
CA2954599A1 (en) 2016-02-18
AU2015302959B2 (en) 2018-09-20
DOP2017000045A (es) 2017-05-15
KR20170040249A (ko) 2017-04-12
AP2017009719A0 (en) 2017-01-31
PE20170903A1 (es) 2017-07-12
AU2015302959A1 (en) 2017-02-02
CN106659790A (zh) 2017-05-10
US20160046711A1 (en) 2016-02-18
UY36266A (es) 2016-04-01
NI201700016A (es) 2017-03-08
US9982045B2 (en) 2018-05-29
SG11201700254QA (en) 2017-02-27
EA201790334A1 (ru) 2017-06-30
CL2017000170A1 (es) 2017-07-14
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