TR199902803T2 - VCAM-1' in teshisinin daraltilmasi için bilesikler ve metodlar. - Google Patents

VCAM-1' in teshisinin daraltilmasi için bilesikler ve metodlar.

Info

Publication number
TR199902803T2
TR199902803T2 TR1999/02803T TR9902803T TR199902803T2 TR 199902803 T2 TR199902803 T2 TR 199902803T2 TR 1999/02803 T TR1999/02803 T TR 1999/02803T TR 9902803 T TR9902803 T TR 9902803T TR 199902803 T2 TR199902803 T2 TR 199902803T2
Authority
TR
Turkey
Prior art keywords
vcam
diagnosis
compounds
methods
narrowing
Prior art date
Application number
TR1999/02803T
Other languages
English (en)
Inventor
Q. Meng Charles
K. Somers Patricia
K. Hoong Lee
Original Assignee
Atherogenics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atherogenics, Inc. filed Critical Atherogenics, Inc.
Publication of TR199902803T2 publication Critical patent/TR199902803T2/tr

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/21—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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    • C07—ORGANIC CHEMISTRY
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    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
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    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton

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  • Health & Medical Sciences (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bu blus VCAM-1' in teshisinin daraltilmasi için bilesikler ve metotlarin bulundugu alanda olup, özellikle, kalp-damar ve atesli hastaliklar dahil, VCAM-1 tarafindan gözlemlenen hastaliklarin tedavisi içindir.
TR1999/02803T 1997-05-14 1998-05-14 VCAM-1' in teshisinin daraltilmasi için bilesikler ve metodlar. TR199902803T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4702097P 1997-05-14 1997-05-14

Publications (1)

Publication Number Publication Date
TR199902803T2 true TR199902803T2 (tr) 2000-07-21

Family

ID=21946634

Family Applications (2)

Application Number Title Priority Date Filing Date
TR1999/02802T TR199902802T2 (tr) 1997-05-14 1998-05-14 Kardiyovasküler hastaliklar ve enflamatuar hastaliklarin tedavisi için probukol monoesterleri.
TR1999/02803T TR199902803T2 (tr) 1997-05-14 1998-05-14 VCAM-1' in teshisinin daraltilmasi için bilesikler ve metodlar.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR1999/02802T TR199902802T2 (tr) 1997-05-14 1998-05-14 Kardiyovasküler hastaliklar ve enflamatuar hastaliklarin tedavisi için probukol monoesterleri.

Country Status (26)

Country Link
US (9) US6121319A (tr)
EP (2) EP0994853B1 (tr)
JP (4) JP2001524986A (tr)
KR (5) KR20010012504A (tr)
CN (7) CN1275596C (tr)
AT (3) ATE294158T1 (tr)
AU (2) AU750041B2 (tr)
BR (2) BR9809819A (tr)
CA (3) CA2292388C (tr)
CY (1) CY1107645T1 (tr)
CZ (4) CZ301302B6 (tr)
DE (3) DE69831566T2 (tr)
DK (2) DK1464639T3 (tr)
EA (5) EA010183B1 (tr)
ES (3) ES2241139T3 (tr)
HK (2) HK1024629A1 (tr)
HU (2) HUP0004592A3 (tr)
ID (2) ID29158A (tr)
IL (7) IL164568A0 (tr)
NO (3) NO316221B1 (tr)
NZ (2) NZ501069A (tr)
PL (2) PL194329B1 (tr)
PT (1) PT1464639E (tr)
SK (4) SK285695B6 (tr)
TR (2) TR199902802T2 (tr)
WO (2) WO1998051662A2 (tr)

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