PL1603553T3 - Kompozycje farmaceutyczne inhibitorów CETP - Google Patents
Kompozycje farmaceutyczne inhibitorów CETPInfo
- Publication number
- PL1603553T3 PL1603553T3 PL04721345T PL04721345T PL1603553T3 PL 1603553 T3 PL1603553 T3 PL 1603553T3 PL 04721345 T PL04721345 T PL 04721345T PL 04721345 T PL04721345 T PL 04721345T PL 1603553 T3 PL1603553 T3 PL 1603553T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical compositions
- cetp inhibitors
- inhibitor
- cept
- administration
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title abstract 2
- 108010061846 Cholesterol Ester Transfer Proteins Proteins 0.000 abstract 2
- 102000012336 Cholesterol Ester Transfer Proteins Human genes 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 229940125881 cholesteryl ester transfer protein inhibitor Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45529303P | 2003-03-17 | 2003-03-17 | |
| US46052103P | 2003-04-04 | 2003-04-04 | |
| US47720203P | 2003-06-10 | 2003-06-10 | |
| US49364903P | 2003-08-08 | 2003-08-08 | |
| PCT/JP2004/003585 WO2004082593A2 (en) | 2003-03-17 | 2004-03-17 | Pharmaceutical compositions of cetp inhibitors |
| EP04721345A EP1603553B9 (en) | 2003-03-17 | 2004-03-17 | Pharmaceutical compositions of cetp inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1603553T3 true PL1603553T3 (pl) | 2012-04-30 |
Family
ID=33033290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04721345T PL1603553T3 (pl) | 2003-03-17 | 2004-03-17 | Kompozycje farmaceutyczne inhibitorów CETP |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20040225018A1 (pl) |
| EP (2) | EP1603553B9 (pl) |
| JP (2) | JP5546715B2 (pl) |
| KR (2) | KR20080008440A (pl) |
| AT (1) | ATE534381T1 (pl) |
| AU (1) | AU2004222434B2 (pl) |
| BR (1) | BRPI0408466B8 (pl) |
| CA (1) | CA2519432C (pl) |
| CO (1) | CO5640101A2 (pl) |
| CY (1) | CY1112324T1 (pl) |
| DK (1) | DK1603553T3 (pl) |
| ES (1) | ES2377121T3 (pl) |
| IL (1) | IL170749A (pl) |
| MX (1) | MXPA05009848A (pl) |
| NO (1) | NO336891B1 (pl) |
| NZ (1) | NZ542852A (pl) |
| PL (1) | PL1603553T3 (pl) |
| PT (1) | PT1603553E (pl) |
| SI (1) | SI1603553T1 (pl) |
| WO (1) | WO2004082593A2 (pl) |
Families Citing this family (24)
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|---|---|---|---|---|
| US7879840B2 (en) | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7393652B2 (en) | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
| US7718644B2 (en) | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
| US7186735B2 (en) * | 2002-08-07 | 2007-03-06 | Sanofi-Aventis Deutschland Gmbh | Acylated arylcycloalkylamines and their use as pharmaceuticals |
| US7544678B2 (en) | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
| JP2007525165A (ja) | 2003-03-07 | 2007-09-06 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | タイプ1ライアノジン受容体に基づく方法 |
| KR20050110017A (ko) | 2003-03-17 | 2005-11-22 | 니뽄 다바코 산교 가부시키가이샤 | S-'2-(''1-(2-에틸부틸)시클로헥실!카르보닐!아미노)페닐!-2-메틸프로판티오에이트의 경구 생체이용율을증가시키는 방법 |
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| TWI494102B (zh) * | 2003-05-02 | 2015-08-01 | Japan Tobacco Inc | 包含s-〔2(〔〔1-(2-乙基丁基)環己基〕羰基〕胺基)苯基〕2-甲基丙烷硫酯及hmg輔酶a還原酶抑制劑之組合 |
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| US8710045B2 (en) | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
| DOP2005000123A (es) | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
| WO2006098394A1 (ja) * | 2005-03-14 | 2006-09-21 | Japan Tobacco Inc. | 脂質吸収抑制方法および脂質吸収抑制剤 |
| US7704990B2 (en) | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| WO2007092642A2 (en) | 2006-02-09 | 2007-08-16 | Merck & Co., Inc. | Polymer formulations of cetp inhibitors |
| EP2373344B1 (en) * | 2008-12-08 | 2016-03-30 | F. Hoffmann-La Roche AG | Combined drug administration |
| CN102293734A (zh) * | 2010-06-25 | 2011-12-28 | 江苏恒瑞医药股份有限公司 | 托伐普坦固体分散体及其制备方法 |
| EP2635263B1 (en) * | 2010-11-04 | 2015-09-23 | F.Hoffmann-La Roche Ag | A composition comprising s-[2-([[1-(2-ethylbutyl)-cyclohexyl]-carbonyl]amino)phenyl]2-methylpropanethioate and croscarmellose sodium |
| CA2818018C (en) * | 2010-12-08 | 2016-02-02 | F. Hoffmann-La Roche Ag | Liposomal formulation of dalcetrapib |
| JP2014505714A (ja) * | 2011-02-17 | 2014-03-06 | エフ.ホフマン−ラ ロシュ アーゲー | ホットメルト押出法による過冷却液体状態からの活性医薬成分の制御された結晶化方法 |
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| PL368850A1 (pl) * | 2001-06-21 | 2005-04-04 | Pfizer Products Inc. | Samoemulgujące preparaty inhibitorów białka przenoszącego estry cholesterylu |
| EP1269994A3 (en) * | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmaceutical compositions comprising drug and concentration-enhancing polymers |
| WO2003000235A1 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions of dispersions of drugs and neutral polymers |
| AR038375A1 (es) * | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
| US20040053842A1 (en) * | 2002-07-02 | 2004-03-18 | Pfizer Inc. | Methods of treatment with CETP inhibitors and antihypertensive agents |
| US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
| MXPA05009848A (es) * | 2003-03-17 | 2005-12-06 | Japan Tobacco Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia del ester de colesterilo. |
-
2004
- 2004-03-17 MX MXPA05009848A patent/MXPA05009848A/es active IP Right Grant
- 2004-03-17 JP JP2006507668A patent/JP5546715B2/ja not_active Expired - Lifetime
- 2004-03-17 WO PCT/JP2004/003585 patent/WO2004082593A2/en not_active Ceased
- 2004-03-17 ES ES04721345T patent/ES2377121T3/es not_active Expired - Lifetime
- 2004-03-17 AT AT04721345T patent/ATE534381T1/de active
- 2004-03-17 EP EP04721345A patent/EP1603553B9/en not_active Expired - Lifetime
- 2004-03-17 DK DK04721345.9T patent/DK1603553T3/da active
- 2004-03-17 PL PL04721345T patent/PL1603553T3/pl unknown
- 2004-03-17 CA CA002519432A patent/CA2519432C/en not_active Expired - Fee Related
- 2004-03-17 US US10/802,220 patent/US20040225018A1/en not_active Abandoned
- 2004-03-17 EP EP10179280A patent/EP2289507A1/en not_active Withdrawn
- 2004-03-17 KR KR1020087000175A patent/KR20080008440A/ko not_active Withdrawn
- 2004-03-17 BR BRPI0408466A patent/BRPI0408466B8/pt not_active IP Right Cessation
- 2004-03-17 AU AU2004222434A patent/AU2004222434B2/en not_active Expired
- 2004-03-17 PT PT04721345T patent/PT1603553E/pt unknown
- 2004-03-17 KR KR1020057017449A patent/KR100857759B1/ko not_active Expired - Lifetime
- 2004-03-17 SI SI200431822T patent/SI1603553T1/sl unknown
- 2004-03-17 NZ NZ542852A patent/NZ542852A/en not_active IP Right Cessation
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2005
- 2005-09-08 IL IL170749A patent/IL170749A/en active IP Right Grant
- 2005-10-14 CO CO05105279A patent/CO5640101A2/es not_active Application Discontinuation
- 2005-10-14 NO NO20054740A patent/NO336891B1/no not_active IP Right Cessation
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2010
- 2010-11-10 JP JP2010252215A patent/JP2011052006A/ja active Pending
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2012
- 2012-02-06 CY CY20121100126T patent/CY1112324T1/el unknown
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2013
- 2013-07-26 US US13/951,909 patent/US20140243414A1/en not_active Abandoned
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