DE3674014D1 - Disubstituierte 4-hydroxyphenylthio-anilide. - Google Patents
Disubstituierte 4-hydroxyphenylthio-anilide.Info
- Publication number
- DE3674014D1 DE3674014D1 DE8686101296T DE3674014T DE3674014D1 DE 3674014 D1 DE3674014 D1 DE 3674014D1 DE 8686101296 T DE8686101296 T DE 8686101296T DE 3674014 T DE3674014 T DE 3674014T DE 3674014 D1 DE3674014 D1 DE 3674014D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxyphenylthio
- anilides
- disubstituted
- hydroxyphenylthio anilides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69804985A | 1985-02-04 | 1985-02-04 | |
US80996585A | 1985-12-20 | 1985-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3674014D1 true DE3674014D1 (de) | 1990-10-18 |
Family
ID=27106142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686101296T Expired - Fee Related DE3674014D1 (de) | 1985-02-04 | 1986-01-31 | Disubstituierte 4-hydroxyphenylthio-anilide. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0190682B1 (de) |
JP (1) | JPH0662556B2 (de) |
AU (1) | AU584669B2 (de) |
DE (1) | DE3674014D1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3700729A1 (de) * | 1987-01-13 | 1988-07-21 | Boehringer Mannheim Gmbh | Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
US4835189A (en) * | 1987-06-05 | 1989-05-30 | G. D. Searle & Co. | Phenolic thioalkylamides as inhibitors of 5-lipoxygenase |
US5002967A (en) * | 1987-06-05 | 1991-03-26 | G. D. Searle & Co. | Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase |
JPS63310821A (ja) * | 1987-06-05 | 1988-12-19 | ジー.ディー.サール アンド カンパニー | 5−リポキシゲナーゼの阻害剤としてのフエノール性チオエーテル、スルホキサイドおよびジスルフアイド |
JP2754039B2 (ja) * | 1988-06-24 | 1998-05-20 | 塩野義製薬株式会社 | ジ―tert―ブチルヒドロキシフェニルチオ誘導体 |
JP2627003B2 (ja) * | 1989-01-25 | 1997-07-02 | 塩野義製薬株式会社 | ジーtert―ブチルヒドロキシフェニルチオ誘導体 |
JP3065636B2 (ja) * | 1989-06-29 | 2000-07-17 | 塩野義製薬株式会社 | [ジ―tert―ブチル(ヒドロキシ)フェニルチオ]置換ヒドロキサム酸誘導体 |
AU8440991A (en) * | 1990-09-07 | 1992-03-30 | G.D. Searle & Co. | Phenolic thioetheramides as 5-lipoxygenase inhibitors |
US5189038A (en) * | 1990-09-07 | 1993-02-23 | G. D. Searle And Co. | Method of stimulating superoxide generation |
US5082854A (en) * | 1990-09-07 | 1992-01-21 | G. D. Searle & Co. | Method of stimulating superoxide generation |
WO1992007825A1 (en) * | 1990-11-05 | 1992-05-14 | Taisho Pharmaceutical Co., Ltd. | Phenol derivative |
ES2088574T3 (es) * | 1990-11-26 | 1996-08-16 | Taisho Pharmaceutical Co Ltd | Derivado de anilida. |
US6218437B1 (en) | 1996-09-30 | 2001-04-17 | The Regents Of The University Of California | Treatment and prevention of hepatic disorders |
AU2006202461B2 (en) * | 1997-05-14 | 2009-12-03 | Atherogenics, Inc. | Compositions and methods for the inhibition of the expression of VCAM-1 |
US6852878B2 (en) | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
CN1275596C (zh) * | 1997-05-14 | 2006-09-20 | 阿特罗吉尼克斯公司 | 普罗布考单酯在制备用于治疗心血管疾病和炎性疾病的药物中的应用 |
EP1695959A1 (de) * | 1997-05-14 | 2006-08-30 | Atherogenics, Inc. | Verbindungen und Methoden zur Hemmung der VCAM-1 Expression |
US7012159B1 (en) | 1999-10-04 | 2006-03-14 | Nippon Soda Co., Ltd. | Phenolic compounds and recording materials containing the same |
WO2005102323A2 (en) | 2004-04-20 | 2005-11-03 | Atherogenics, Inc. | Process of preparing esters and ethers of probucol and derivatives thereof |
CA2682258A1 (en) | 2007-03-26 | 2008-10-02 | Salutria Pharmaceuticals Llc | Methods and compositions of derivatives of probucol for the treatment of diabetes |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1936463A1 (de) * | 1969-07-17 | 1971-02-04 | Boehringer Sohn Ingelheim | Substituierte Phenole |
US4029812A (en) * | 1976-02-18 | 1977-06-14 | The Dow Chemical Company | Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides |
JPS6039262B2 (ja) * | 1977-05-11 | 1985-09-05 | ウェルファイド株式会社 | 第3級ブチルフェノ−ル誘導体 |
US4755524A (en) * | 1986-01-31 | 1988-07-05 | G. D. Searle & Co. | Novel phenolic thioethers as inhibitors of 5-lipoxygenase |
-
1986
- 1986-01-31 AU AU52886/86A patent/AU584669B2/en not_active Ceased
- 1986-01-31 EP EP86101296A patent/EP0190682B1/de not_active Expired - Lifetime
- 1986-01-31 DE DE8686101296T patent/DE3674014D1/de not_active Expired - Fee Related
- 1986-02-03 JP JP61021874A patent/JPH0662556B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0190682A3 (en) | 1988-01-07 |
EP0190682B1 (de) | 1990-09-12 |
AU5288686A (en) | 1986-08-14 |
JPH0662556B2 (ja) | 1994-08-17 |
AU584669B2 (en) | 1989-06-01 |
EP0190682A2 (de) | 1986-08-13 |
JPS61197554A (ja) | 1986-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |