FR2140771A5 - Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc - Google Patents

Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc

Info

Publication number
FR2140771A5
FR2140771A5 FR7120546A FR7120546A FR2140771A5 FR 2140771 A5 FR2140771 A5 FR 2140771A5 FR 7120546 A FR7120546 A FR 7120546A FR 7120546 A FR7120546 A FR 7120546A FR 2140771 A5 FR2140771 A5 FR 2140771A5
Authority
FR
France
Prior art keywords
bis
hypolipemics
hydroxyphenylthio
alkanes
alkanoic esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7120546A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7120546A priority Critical patent/FR2140771A5/en
Application granted granted Critical
Publication of FR2140771A5 publication Critical patent/FR2140771A5/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Abstract

Title cpds. are of formula (I): (where R1 = H or lower alkyl, R2 = CH3 or C2H5; R3 = tert. amyl or tert. butyl, R4 = lower alkyl, X is a grp. (II): B = divalent satd. or ethylenic, straight or branched hydrocarbon). The cpds. have pharmacodynamic, hypocholesterolemic and hypolipemic properties. They are prepd. by esterification of the appropriate bis(dihydrodiphenylthio)alkane with XCOOH or its chloride or anhydride.
FR7120546A 1971-06-07 1971-06-07 Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc Expired FR2140771A5 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7120546A FR2140771A5 (en) 1971-06-07 1971-06-07 Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7120546A FR2140771A5 (en) 1971-06-07 1971-06-07 Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc

Publications (1)

Publication Number Publication Date
FR2140771A5 true FR2140771A5 (en) 1973-01-19

Family

ID=9078218

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7120546A Expired FR2140771A5 (en) 1971-06-07 1971-06-07 Tetralinyl phenoxy alkanoic esters - of bis hydroxyphenylthio alkanes, hypolipemics etc

Country Status (1)

Country Link
FR (1) FR2140771A5 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121319A (en) * 1997-05-14 2000-09-19 Atherogenics, Inc. Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
US6960683B2 (en) 2002-07-12 2005-11-01 Atherogenics, Inc. Salt forms of poorly soluble probucol esters and ethers
US7071158B2 (en) 1997-07-01 2006-07-04 Atherogenics, Inc. Antioxidant enhancement of therapy for hyperproliferative conditions
US7087645B2 (en) 1997-05-14 2006-08-08 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US7166605B2 (en) 2002-03-22 2007-01-23 Nicox, S.A. Probucol nitro-derivatives
US7271274B2 (en) 2004-04-20 2007-09-18 Ahterogenics, Inc. Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease
US7273948B2 (en) 2003-01-13 2007-09-25 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
US7294737B2 (en) 2004-04-20 2007-11-13 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
WO2008118948A1 (en) 2007-03-26 2008-10-02 Atherogenics, Inc. Methods and compositions of derivatives of probucol for the treatment of diabetes
US7687659B2 (en) 2005-04-21 2010-03-30 Salutria Pharmaceuticals Llc Process for the separation of probucol derivatives
US7897776B2 (en) 2007-04-23 2011-03-01 Salutria Pharmaceuticals Llc Sulfonamide containing compounds for treatment of inflammatory disorders

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147250A (en) * 1997-05-14 2000-11-14 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US6548699B1 (en) 1997-05-14 2003-04-15 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US7087645B2 (en) 1997-05-14 2006-08-08 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US7189870B2 (en) 1997-05-14 2007-03-13 Atherogenic, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US6121319A (en) * 1997-05-14 2000-09-19 Atherogenics, Inc. Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
US7071158B2 (en) 1997-07-01 2006-07-04 Atherogenics, Inc. Antioxidant enhancement of therapy for hyperproliferative conditions
US7166605B2 (en) 2002-03-22 2007-01-23 Nicox, S.A. Probucol nitro-derivatives
US7371895B2 (en) 2002-07-12 2008-05-13 Atherogenics, Inc. Salt forms of poorly soluble probucol esters and ethers
US6960683B2 (en) 2002-07-12 2005-11-01 Atherogenics, Inc. Salt forms of poorly soluble probucol esters and ethers
US7273948B2 (en) 2003-01-13 2007-09-25 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
US7622604B2 (en) 2003-01-13 2009-11-24 Salutria Pharmaceuticals Llc Process of preparing esters and ethers of probucol and derivatives thereof
US7271274B2 (en) 2004-04-20 2007-09-18 Ahterogenics, Inc. Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease
US7294737B2 (en) 2004-04-20 2007-11-13 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
US7687659B2 (en) 2005-04-21 2010-03-30 Salutria Pharmaceuticals Llc Process for the separation of probucol derivatives
WO2008118948A1 (en) 2007-03-26 2008-10-02 Atherogenics, Inc. Methods and compositions of derivatives of probucol for the treatment of diabetes
US8252840B2 (en) 2007-03-26 2012-08-28 Salutria Pharmaceuticals Llc Methods of derivatives of probucol for the treatment of type II diabetes
US7897776B2 (en) 2007-04-23 2011-03-01 Salutria Pharmaceuticals Llc Sulfonamide containing compounds for treatment of inflammatory disorders

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Legal Events

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