RU2139351C1 - Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности - Google Patents

Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности Download PDF

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RU2139351C1
RU2139351C1 RU93055358A RU93055358A RU2139351C1 RU 2139351 C1 RU2139351 C1 RU 2139351C1 RU 93055358 A RU93055358 A RU 93055358A RU 93055358 A RU93055358 A RU 93055358A RU 2139351 C1 RU2139351 C1 RU 2139351C1
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chain
human
region
antibodies
regions
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RU93055358A
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RU93055358A (ru
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Тсутия Масаюки
Сато Кох
Маргарет Бендиг Мэри
Тарран Джонс Стивен
Уильям Салданха Жозе
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Чугаи Сейяку Кабусики Кайся
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Priority claimed from JP3095476A external-priority patent/JPH05236966A/ja
Priority claimed from JP4032084A external-priority patent/JPH05227970A/ja
Application filed by Чугаи Сейяку Кабусики Кайся filed Critical Чугаи Сейяку Кабусики Кайся
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU93055358A 1991-04-25 1992-04-24 Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности RU2139351C1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP3-95476 1991-04-25
JP3095476A JPH05236966A (ja) 1991-04-25 1991-04-25 ヒトインターロイキン−６レセプターに対するマウスモノクローナル抗体の可変領域をコードするｄｎａ
JP4032084A JPH05227970A (ja) 1992-02-19 1992-02-19 ヒトインターロイキン−６受容体に対する再構成ヒト抗体
JP4-32084 1992-02-19
PCT/JP1992/000544 WO1992019759A1 (fr) 1991-04-25 1992-04-24 Anticorps humains reconstitues diriges contre un recepteur de l'interleukine 6 humaine

Publications (2)

Publication Number Publication Date
RU93055358A RU93055358A (ru) 1997-02-10
RU2139351C1 true RU2139351C1 (ru) 1999-10-10

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ID=26370596

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93055358A RU2139351C1 (ru) 1991-04-25 1992-04-24 Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности

Country Status (16)

Country Link
US (3) US5795965A (en:Method)
EP (1) EP0628639B1 (en:Method)
JP (6) JP3370324B2 (en:Method)
KR (1) KR100249937B1 (en:Method)
AT (1) ATE181575T1 (en:Method)
AU (2) AU668349B2 (en:Method)
DE (2) DE69229482T2 (en:Method)
DK (1) DK0628639T3 (en:Method)
ES (1) ES2134212T3 (en:Method)
GR (1) GR3031174T3 (en:Method)
HU (1) HU218140B (en:Method)
LU (1) LU91556I2 (en:Method)
NL (1) NL300383I2 (en:Method)
RU (1) RU2139351C1 (en:Method)
TW (1) TW205553B (en:Method)
WO (1) WO1992019759A1 (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2430111C1 (ru) * 2008-09-26 2011-09-27 Чугаи Сейяку Кабусики Кайся Молекулы антител с улучшенными свойствами

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