ATE297219T1 - Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) - Google Patents

Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome)

Info

Publication number
ATE297219T1
ATE297219T1 AT98902757T AT98902757T ATE297219T1 AT E297219 T1 ATE297219 T1 AT E297219T1 AT 98902757 T AT98902757 T AT 98902757T AT 98902757 T AT98902757 T AT 98902757T AT E297219 T1 ATE297219 T1 AT E297219T1
Authority
AT
Austria
Prior art keywords
myelomas
medicinal
antibodies
exclusively
lymphocytic tumors
Prior art date
Application number
AT98902757T
Other languages
English (en)
Inventor
Yasuo Koishihara
Yasushi Yoshimura
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE297219T1 publication Critical patent/ATE297219T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT98902757T 1997-02-12 1998-02-12 Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) ATE297219T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4141097 1997-02-12
PCT/JP1998/000568 WO1998035698A1 (fr) 1997-02-12 1998-02-12 Remedes contre les tumeurs lymphocitaires

Publications (1)

Publication Number Publication Date
ATE297219T1 true ATE297219T1 (de) 2005-06-15

Family

ID=12607597

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98902757T ATE297219T1 (de) 1997-02-12 1998-02-12 Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome)

Country Status (20)

Country Link
US (2) US6503510B2 (de)
EP (1) EP0997152B1 (de)
KR (2) KR100655979B1 (de)
CN (1) CN1191855C (de)
AT (1) ATE297219T1 (de)
AU (1) AU724133B2 (de)
BR (1) BR9811094A (de)
CA (1) CA2280875C (de)
DE (1) DE69830492T2 (de)
ES (1) ES2241114T3 (de)
HK (1) HK1026368A1 (de)
HU (1) HUP0001136A3 (de)
IL (1) IL131381A0 (de)
NO (1) NO993866L (de)
PL (1) PL190065B1 (de)
RU (1) RU2177805C2 (de)
SK (1) SK110099A3 (de)
TR (1) TR199901949T2 (de)
UA (1) UA65561C2 (de)
WO (1) WO1998035698A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW474991B (en) * 1993-10-15 2002-02-01 Toshio Hirano Membrane protein polypeptide having function of pre-B cell proliferation and the encoded gene thereof
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
JP3609026B2 (ja) * 1998-02-25 2005-01-12 中外製薬株式会社 抗ｈｍ１．２４抗体の免疫化学的測定方法
ATE404216T1 (de) * 1999-08-23 2008-08-15 Chugai Pharmaceutical Co Ltd Verstärker der hm1.24 antigen-expression
WO2002057316A1 (fr) * 2000-12-28 2002-07-25 Kirin Beer Kabushiki Kaisha Nouvel anticorps monoclonal
US7931897B2 (en) 2001-02-07 2011-04-26 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for hematopoietic tumors
ES2869895T3 (es) 2001-03-09 2021-10-26 Chugai Pharmaceutical Co Ltd Método de purificación de proteínas
US7888478B2 (en) 2002-09-11 2011-02-15 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US20050226869A1 (en) * 2001-10-19 2005-10-13 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US7858330B2 (en) 2001-10-19 2010-12-28 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
AU2003211991B2 (en) * 2002-02-14 2008-08-21 Chugai Seiyaku Kabushiki Kaisha Antibody-containing solution formulations
US20030223998A1 (en) * 2002-02-27 2003-12-04 Lamb Lawrence S. Targeted immunotherapy of acute lymphoblastic leukemia (ALL)
US20080219974A1 (en) * 2002-03-01 2008-09-11 Bernett Matthew J Optimized antibodies that target hm1.24
EP1666501A4 (de) * 2003-08-11 2008-12-24 Chugai Pharmaceutical Co Ltd Zuckerkettenmodifizierter anti-hm1.24-antikörper
JP4794303B2 (ja) * 2003-10-10 2011-10-19 中外製薬株式会社 固形腫瘍治療剤
US7867734B2 (en) * 2004-10-26 2011-01-11 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody having modified sugar chain
US8329186B2 (en) 2004-12-20 2012-12-11 Isu Abxis Co., Ltd Treatment of inflammation using BST2 inhibitor
US20080299128A1 (en) 2006-06-20 2008-12-04 Myung Kim Effect of Bst2 on inflammation
AU2007299843B2 (en) 2006-09-18 2012-03-08 Xencor, Inc Optimized antibodies that target HM1.24
EP2210939A4 (de) 2007-10-16 2012-08-08 Sbi Biotech Co Ltd Anti-bst2-antikörper
TWI516501B (zh) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Ｐｃｓｋ９拮抗劑類
US9123149B2 (en) * 2013-03-15 2015-09-01 Columbia Insurance Company Expert color system for color selection with color harmony and color emotion intelligence
CN107619443B (zh) * 2016-07-14 2020-08-14 深圳宾德生物技术有限公司 抗人和鼠cd317的单克隆抗体及其制备方法和应用
CN109748964B (zh) * 2017-11-01 2020-11-17 深圳宾德生物技术有限公司 CD317单链抗体317scFv、其编码序列及制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650150A (en) * 1990-11-09 1997-07-22 Gillies; Stephen D. Recombinant antibody cytokine fusion proteins
US5795965A (en) 1991-04-25 1998-08-18 Chugai Seiyaku Kabushiki Kaisha Reshaped human to human interleukin-6 receptor
TW474991B (en) * 1993-10-15 2002-02-01 Toshio Hirano Membrane protein polypeptide having function of pre-B cell proliferation and the encoded gene thereof
UA76934C2 (en) 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
EP0972524A4 (de) 1997-02-28 2001-03-28 Chugai Pharmaceutical Co Ltd Lymphozyten aktivierungsinhibitoren
DE69838454T2 (de) * 1997-10-03 2008-02-07 Chugai Seiyaku K.K. Natürlicher menschlicher antikörper
CN101073667B (zh) 1997-10-14 2013-11-06 中外制药株式会社 淋巴细胞肿瘤抗体的增强剂

Also Published As

Publication number Publication date
TR199901949T2 (xx) 2000-01-21
US20020037288A1 (en) 2002-03-28
HUP0001136A2 (hu) 2000-08-28
NO993866L (no) 1999-10-11
HUP0001136A3 (en) 2002-02-28
PL190065B1 (pl) 2005-10-31
IL131381A0 (en) 2001-01-28
CA2280875C (en) 2005-07-05
AU724133B2 (en) 2000-09-14
SK110099A3 (en) 2000-08-14
RU2177805C2 (ru) 2002-01-10
UA65561A (en) 2000-08-15
EP0997152A4 (de) 2001-04-18
UA65561C2 (uk) 2004-04-15
BR9811094A (pt) 2000-07-18
EP0997152B1 (de) 2005-06-08
CN1191855C (zh) 2005-03-09
WO1998035698A1 (fr) 1998-08-20
US20030113334A1 (en) 2003-06-19
KR100655979B1 (ko) 2006-12-08
PL335140A1 (en) 2000-04-10
DE69830492T2 (de) 2006-03-16
KR20030097614A (ko) 2003-12-31
NO993866D0 (no) 1999-08-11
AU5956398A (en) 1998-09-08
ES2241114T3 (es) 2005-10-16
HK1026368A1 (en) 2000-12-15
CN1250381A (zh) 2000-04-12
EP0997152A1 (de) 2000-05-03
CA2280875A1 (en) 1998-08-20
DE69830492D1 (de) 2005-07-14
US6503510B2 (en) 2003-01-07
KR20000070989A (ko) 2000-11-25

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