CY1110128T1 - Καταλυτικα μονοκλωνικα αντισωματα με δραστικοτητα πρωτεασης για την εκλεκτικη λυση του πρωτεϊνικου συστατικου των πλακων και συνονθυλευματων που σχετιζονται με παθολογικες καταστασεις - Google Patents

Καταλυτικα μονοκλωνικα αντισωματα με δραστικοτητα πρωτεασης για την εκλεκτικη λυση του πρωτεϊνικου συστατικου των πλακων και συνονθυλευματων που σχετιζονται με παθολογικες καταστασεις

Info

Publication number
CY1110128T1
CY1110128T1 CY20101100487T CY101100487T CY1110128T1 CY 1110128 T1 CY1110128 T1 CY 1110128T1 CY 20101100487 T CY20101100487 T CY 20101100487T CY 101100487 T CY101100487 T CY 101100487T CY 1110128 T1 CY1110128 T1 CY 1110128T1
Authority
CY
Cyprus
Prior art keywords
monoclonal antibodies
slabs
wires
protease activity
protein ingredient
Prior art date
Application number
CY20101100487T
Other languages
English (en)
Inventor
Silvia Trasciatti
Sergio Rosini
Original Assignee
Abiogen Pharma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma S.P.A. filed Critical Abiogen Pharma S.P.A.
Publication of CY1110128T1 publication Critical patent/CY1110128T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Καταλυτικά μονοκλωνικά αντισώματα (προϊόντα αντισώματος-ενζύμου) με εκλεκτική δραστικότητα πρωτεάσης στις παθολογίες που χαρακτηρίζονται από την παρουσία πλακών και ινιδωδών συνονθυλευμάτων με πρωτεϊνικό συστατικό, μέθοδοι για την παρασκευή αυτών και την χρήση αυτών ως φαρμάκων στην θεραπεία παθολογιών όπως της ασθένειας Alzheimer, και των ασθενειών αμυλοείδωσης, αθηροσκλήρωσης, πριόντων.
CY20101100487T 1997-07-30 2010-06-03 Καταλυτικα μονοκλωνικα αντισωματα με δραστικοτητα πρωτεασης για την εκλεκτικη λυση του πρωτεϊνικου συστατικου των πλακων και συνονθυλευματων που σχετιζονται με παθολογικες καταστασεις CY1110128T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI001826A IT1293511B1 (it) 1997-07-30 1997-07-30 Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
EP98945101A EP0996463B1 (en) 1997-07-30 1998-07-28 Catalytic monoclonal antibodies with protease activity for the selective lysis of the protein component of plaques and aggregates related to pathological conditions

Publications (1)

Publication Number Publication Date
CY1110128T1 true CY1110128T1 (el) 2015-01-14

Family

ID=11377678

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100487T CY1110128T1 (el) 1997-07-30 2010-06-03 Καταλυτικα μονοκλωνικα αντισωματα με δραστικοτητα πρωτεασης για την εκλεκτικη λυση του πρωτεϊνικου συστατικου των πλακων και συνονθυλευματων που σχετιζονται με παθολογικες καταστασεις

Country Status (17)

Country Link
US (1) US6387674B1 (el)
EP (1) EP0996463B1 (el)
JP (1) JP2001511369A (el)
CN (1) CN1268175A (el)
AT (1) ATE466883T1 (el)
AU (1) AU741368B2 (el)
CA (1) CA2299442C (el)
CY (1) CY1110128T1 (el)
DE (1) DE69841653D1 (el)
DK (1) DK0996463T3 (el)
ES (1) ES2340892T3 (el)
IL (1) IL134142A0 (el)
IT (1) IT1293511B1 (el)
NO (1) NO329769B1 (el)
NZ (1) NZ502527A (el)
PT (1) PT996463E (el)
WO (1) WO1999006066A2 (el)

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Also Published As

Publication number Publication date
NO20000396L (no) 2000-03-29
DK0996463T3 (da) 2010-08-09
CN1268175A (zh) 2000-09-27
JP2001511369A (ja) 2001-08-14
US6387674B1 (en) 2002-05-14
NZ502527A (en) 2003-01-31
IT1293511B1 (it) 1999-03-01
WO1999006066A3 (en) 1999-04-29
CA2299442A1 (en) 1999-02-11
NO329769B1 (no) 2010-12-13
ES2340892T3 (es) 2010-06-10
WO1999006066A2 (en) 1999-02-11
ITMI971826A1 (it) 1999-01-30
ATE466883T1 (de) 2010-05-15
EP0996463A2 (en) 2000-05-03
IL134142A0 (en) 2001-04-30
PT996463E (pt) 2010-05-17
AU741368B2 (en) 2001-11-29
DE69841653D1 (de) 2010-06-17
EP0996463B1 (en) 2010-05-05
AU9255398A (en) 1999-02-22
NO20000396D0 (no) 2000-01-26
CA2299442C (en) 2011-06-21

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