DE68920624D1 - Menschlicher monoklonaler Antikörper, Hybridoma, das ihn herstellt, und pharmazeutisches Mittel. - Google Patents

Menschlicher monoklonaler Antikörper, Hybridoma, das ihn herstellt, und pharmazeutisches Mittel.

Info

Publication number
DE68920624D1
DE68920624D1 DE68920624T DE68920624T DE68920624D1 DE 68920624 D1 DE68920624 D1 DE 68920624D1 DE 68920624 T DE68920624 T DE 68920624T DE 68920624 T DE68920624 T DE 68920624T DE 68920624 D1 DE68920624 D1 DE 68920624D1
Authority
DE
Germany
Prior art keywords
hybridoma
monoclonal antibody
pharmaceutical agent
human monoclonal
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68920624T
Other languages
English (en)
Other versions
DE68920624T2 (de
Inventor
Shinichi Yokota
Hiroshi Ohtsuka
Hiroshi Ochi
Hiroshi Noguchi
Masazumi Terashima
Masuhiro Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of DE68920624D1 publication Critical patent/DE68920624D1/de
Application granted granted Critical
Publication of DE68920624T2 publication Critical patent/DE68920624T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE68920624T 1988-05-10 1989-05-10 Menschlicher monoklonaler Antikörper, Hybridoma, das ihn herstellt, und pharmazeutisches Mittel. Expired - Fee Related DE68920624T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11447388 1988-05-10

Publications (2)

Publication Number Publication Date
DE68920624D1 true DE68920624D1 (de) 1995-03-02
DE68920624T2 DE68920624T2 (de) 1995-07-27

Family

ID=14638614

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68920624T Expired - Fee Related DE68920624T2 (de) 1988-05-10 1989-05-10 Menschlicher monoklonaler Antikörper, Hybridoma, das ihn herstellt, und pharmazeutisches Mittel.

Country Status (10)

Country Link
US (1) US5252480A (de)
EP (1) EP0341684B1 (de)
JP (1) JP2645665B2 (de)
AT (1) AT397803B (de)
BE (1) BE1001964A4 (de)
CH (1) CH681012A5 (de)
DE (1) DE68920624T2 (de)
FR (1) FR2631239B1 (de)
GB (1) GB2218703B (de)
IT (1) IT1232273B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521085A (en) * 1986-12-15 1996-05-28 Mitsui Toatsu Chemicals, Inc. Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes
EP0382031A3 (de) * 1989-02-10 1991-06-26 Miles Inc. Monoklonal-Antikörper in einer Zusammensetzung von Globulin aus Immunserum
JPH02283294A (ja) * 1989-04-24 1990-11-20 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
JPH04211393A (ja) * 1990-02-08 1992-08-03 Sumitomo Pharmaceut Co Ltd ヒトモノクローナル抗体及びそれを有効成分とする緑膿菌感染症治療剤
GB9105292D0 (en) * 1991-03-13 1991-04-24 Sandoz Ltd Improvements in or relating to organic compounds
US5648660A (en) * 1996-01-05 1997-07-15 Sterling Diagnostic Imaging, Inc. Method and apparatus for reducing noise in a radiation capture device
US6197582B1 (en) 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
AU2004202605B2 (en) 1998-07-13 2007-10-25 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US7060802B1 (en) * 2000-09-18 2006-06-13 The Trustees Of Columbia University In The City Of New York Tumor-associated marker
DE60139944D1 (de) * 2000-10-12 2009-10-29 Genentech Inc Niederviskose konzentrierte proteinformulierungen
US8703126B2 (en) 2000-10-12 2014-04-22 Genentech, Inc. Reduced-viscosity concentrated protein formulations
US20040191243A1 (en) * 2002-12-13 2004-09-30 Bei Chen System and method for stabilizing antibodies with histidine
US20050158303A1 (en) * 2003-04-04 2005-07-21 Genentech, Inc. Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations
PT1610820E (pt) * 2003-04-04 2010-12-16 Novartis Ag Formulações de elevada concentração de anticorpos e proteínas
FR2859725B1 (fr) * 2003-09-16 2006-03-10 Neovacs Procede a haut rendement pour l'obtention d'anticorps humains neutralisant l'activite biologique d'une cytokine humaine
BRPI1006519A2 (pt) * 2009-03-06 2016-08-09 Genentech Inc formulação de anticorpos

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
AU597877B2 (en) * 1984-12-26 1990-06-14 Teijin Limited Anti-pseudomonas aeruginosa human monoclonal antibody
WO1986005396A1 (en) * 1985-03-11 1986-09-25 Teijin Limited E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
JPS62215131A (ja) * 1986-03-13 1987-09-21 Kawasaki Heavy Ind Ltd 遠心クラツチ
EP0256713A3 (de) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutische, menschliche Antipseudomonas-Aeruginosa-Antikörper
WO1988008135A1 (en) * 1987-04-10 1988-10-20 Xoma Corporation Human monoclonal antibodies binding determinants of gram negative bacteria

Also Published As

Publication number Publication date
EP0341684A2 (de) 1989-11-15
EP0341684B1 (de) 1995-01-18
FR2631239B1 (fr) 1994-05-27
JP2645665B2 (ja) 1997-08-25
BE1001964A4 (fr) 1990-04-24
GB2218703A (en) 1989-11-22
EP0341684A3 (en) 1990-01-17
IT1232273B (it) 1992-01-28
AT397803B (de) 1994-07-25
DE68920624T2 (de) 1995-07-27
IT8967343A0 (it) 1989-05-09
FR2631239A1 (fr) 1989-11-17
JPH0284197A (ja) 1990-03-26
GB8910395D0 (en) 1989-06-21
GB2218703B (en) 1992-10-28
US5252480A (en) 1993-10-12
CH681012A5 (de) 1992-12-31
ATA111789A (de) 1993-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee