OA11980A - Indazole compounds and pharmaceutical compositionsfor inhibiting protein kinases, and methods for t heir use. - Google Patents

Indazole compounds and pharmaceutical compositionsfor inhibiting protein kinases, and methods for t heir use. Download PDF

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Publication number
OA11980A
OA11980A OA1200100348A OA1200100348A OA11980A OA 11980 A OA11980 A OA 11980A OA 1200100348 A OA1200100348 A OA 1200100348A OA 1200100348 A OA1200100348 A OA 1200100348A OA 11980 A OA11980 A OA 11980A
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OA
OAPI
Prior art keywords
substituted
indazole
found
alkyl
aryl
Prior art date
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OA1200100348A
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English (en)
Inventor
Robert Steven Kania
Steven Lee Bender
Allen J Borchardt
John F Braganza
Stephan James Cripps
Ye Hua
Michael David Johnson
Johnson Theodore Otto Jr
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Agouron Pharma
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22498654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA11980(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agouron Pharma filed Critical Agouron Pharma
Publication of OA11980A publication Critical patent/OA11980A/en

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P17/06—Antipsoriatics
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
OA1200100348A 1999-07-02 2000-06-30 Indazole compounds and pharmaceutical compositionsfor inhibiting protein kinases, and methods for t heir use. OA11980A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14213099P 1999-07-02 1999-07-02

Publications (1)

Publication Number Publication Date
OA11980A true OA11980A (en) 2006-04-18

Family

ID=22498654

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200100348A OA11980A (en) 1999-07-02 2000-06-30 Indazole compounds and pharmaceutical compositionsfor inhibiting protein kinases, and methods for t heir use.

Country Status (52)

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EP (2) EP1218348B1 (xx)
JP (2) JP3878849B2 (xx)
KR (1) KR100529639B1 (xx)
CN (2) CN1234693C (xx)
AP (1) AP1486A (xx)
AR (2) AR035554A1 (xx)
AT (1) ATE376543T1 (xx)
AU (1) AU777701B2 (xx)
BE (1) BE2013C015I2 (xx)
BG (1) BG66070B1 (xx)
BR (1) BRPI0012352B8 (xx)
CA (1) CA2383630C (xx)
CO (1) CO5190686A1 (xx)
CR (2) CR6517A (xx)
CY (3) CY1107147T1 (xx)
CZ (1) CZ301667B6 (xx)
DE (2) DE60037211T2 (xx)
DK (2) DK1614683T3 (xx)
DZ (1) DZ3191A1 (xx)
EA (1) EA004460B1 (xx)
EE (1) EE05585B1 (xx)
ES (2) ES2293906T3 (xx)
FR (1) FR13C0010I2 (xx)
GE (1) GEP20063885B (xx)
GT (1) GT200000107A (xx)
HK (3) HK1048813A1 (xx)
HR (1) HRP20020109B1 (xx)
HU (1) HU228502B1 (xx)
IL (1) IL146710A0 (xx)
IS (1) IS2791B (xx)
JO (1) JO2319B1 (xx)
LU (1) LU92154I2 (xx)
MA (1) MA26803A1 (xx)
ME (1) MEP45108A (xx)
MX (1) MXPA01012795A (xx)
MY (2) MY137622A (xx)
NO (3) NO322507B1 (xx)
NZ (1) NZ516676A (xx)
OA (1) OA11980A (xx)
PA (1) PA8498001A1 (xx)
PE (1) PE20010306A1 (xx)
PL (1) PL212108B1 (xx)
PT (2) PT1218348E (xx)
RS (1) RS50339B (xx)
SI (2) SI1614683T1 (xx)
SK (1) SK286936B6 (xx)
SV (1) SV2002000121A (xx)
TN (1) TNSN00146A1 (xx)
UA (1) UA66933C2 (xx)
UY (1) UY26231A1 (xx)
WO (1) WO2001002369A2 (xx)
ZA (1) ZA200110061B (xx)

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KR100834823B1 (ko) 2000-08-09 2008-06-09 아스트라제네카 아베 신놀린 화합물
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PT1313734E (pt) 2000-09-01 2010-02-09 Novartis Vaccines & Diagnostic Derivados aza heterocíclicos e sua utilização terapêutica
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