|
DE1070639B
(de)
|
|
1959-12-10 |
Farbenfabriken Bayer Aktiengesellschaft, Levenkusen-Bayerwerk |
Verfahren zur Herstellung von Peptiderj
|
|
CH312530A
(de)
|
1952-06-20 |
1955-12-31 |
Ciba Geigy |
Verfahren zur Herstellung eines Pyridazons.
|
|
CH312531A
(de)
|
1952-06-20 |
1955-12-31 |
Ciba Geigy |
Verfahren zur Herstellung eines Pyridazons.
|
|
GB788393A
(en)
|
1953-04-30 |
1958-01-02 |
Ciba Ltd |
Process for the manufacture of pyridazone compounds
|
|
CH333366A
(de)
|
1953-09-04 |
1958-10-15 |
Ciba Geigy |
Verfahren zur Herstellung neuer Pyridazone
|
|
DE1070639C2
(enExample)
|
1958-09-30 |
1964-04-16 |
|
|
|
GB889317A
(en)
|
1959-01-22 |
1962-02-14 |
Ciba Ltd |
New phenyl-diazines and a process for their manufacture
|
|
US3014034A
(en)
|
1959-01-22 |
1961-12-19 |
Ciba Pharm Prod Inc |
1, 3-diaryl, 5-amino-pyridazinones
|
|
DE1936231U
(de)
|
1965-12-06 |
1966-04-07 |
Anton Poettgens |
Betonruettelflasche.
|
|
JPS422264Y1
(enExample)
|
1966-08-10 |
1967-02-10 |
|
|
|
US3622340A
(en)
|
1968-08-12 |
1971-11-23 |
Eastman Kodak Co |
4-thiouracil compounds as fog inhibitors
|
|
UST866035I4
(en)
|
1969-05-05 |
1969-09-30 |
|
Defensive publication |
|
FR2081572B1
(enExample)
|
1970-03-12 |
1973-04-06 |
Rhone Poulenc Sa |
|
|
BE787523A
(fr)
|
1971-08-13 |
1973-02-12 |
Chem Pharmac Fabrik Dr Hermann |
Medicament a base de pyridone-2
|
|
DE2143744A1
(de)
|
1971-09-01 |
1973-03-08 |
Hoechst Ag |
3,4-dihydro-2h-isochinolin-1-one und verfahren zu ihrer herstellung
|
|
US3839346A
(en)
|
1972-12-18 |
1974-10-01 |
Affiliated Med Res |
N-substituted pyridone and general method for preparing pyridones
|
|
GB1458048A
(en)
|
1972-12-18 |
1976-12-08 |
Affiliated Med Res |
Pharmaceutical composition
|
|
US4042699A
(en)
*
|
1972-12-18 |
1977-08-16 |
Affiliated Medical Research, Inc. |
Method for reducing serum glucose levels
|
|
US4052509A
(en)
|
1972-12-18 |
1977-10-04 |
Affiliated Medical Research, Inc. |
Method for reducing serum uric acid levels
|
|
CA1049411A
(en)
*
|
1972-12-18 |
1979-02-27 |
Affiliated Medical Research |
N-substituted pyridone and general method for preparing pyridones
|
|
AT333774B
(de)
|
1974-09-24 |
1976-12-10 |
Chemie Linz Ag |
Verfahren zur herstellung von 3-phenylpyridazonen
|
|
JPS51128438A
(en)
|
1975-04-26 |
1976-11-09 |
Yamanouchi Pharmaceut Co Ltd |
An antibacterial drug against fish diseases
|
|
DE2557342A1
(de)
|
1975-12-19 |
1977-06-30 |
Hoechst Ag |
Basisch substituierte indolderivate und verfahren zu ihrer herstellung
|
|
US4258052A
(en)
|
1976-08-17 |
1981-03-24 |
Yu Ruey J |
Treatment of psoriasis with nicotinamide analogues
|
|
DE2707268A1
(de)
|
1977-02-19 |
1978-08-31 |
Hoechst Ag |
Indol-3-carbaldehyd-oxime und verfahren zu ihrer herstellung
|
|
GB1596887A
(en)
|
1977-07-15 |
1981-09-03 |
Rohm & Haas |
2-pyridone derivatives and their use as plant growth regulators
|
|
JPS557201A
(en)
*
|
1978-05-23 |
1980-01-19 |
Shionogi & Co Ltd |
Derivative of tetrahydrothiopyrano(2,3-b)indole
|
|
GB2044272B
(en)
*
|
1979-02-05 |
1983-03-16 |
Sandoz Ltd |
Stabilising polymers
|
|
DD149666A1
(de)
|
1979-06-27 |
1981-07-22 |
Karl Gewald |
Verfahren zur herstellung von 6-amino-und 6-hydroxy-1-aryl-5-cyan-2(1h)-pyridinonen und-thionen
|
|
JPS5721388A
(en)
|
1980-07-11 |
1982-02-04 |
Nippon Nohyaku Co Ltd |
Condensed pyrazole derivative
|
|
JPS5777671A
(en)
|
1980-10-31 |
1982-05-15 |
Yasumitsu Tamura |
Preparation of hydroxyindoles ( or 1,4-dihydroisoquinolones) and their intermediate
|
|
US4404203A
(en)
*
|
1981-05-14 |
1983-09-13 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4397854A
(en)
*
|
1981-05-14 |
1983-08-09 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4476307A
(en)
|
1982-09-20 |
1984-10-09 |
Pfizer Inc. |
Heteroylidene indolone compounds
|
|
US4473696A
(en)
*
|
1982-10-07 |
1984-09-25 |
Ici Americas Inc. |
Synthesis of 2-substituted-5-methyl-pyridines
|
|
US4645839A
(en)
*
|
1982-12-17 |
1987-02-24 |
Ici Americas Inc. |
Sulphur dehydrogenation process to yield 5-methyl-2-pyridone
|
|
US4650804A
(en)
|
1984-03-30 |
1987-03-17 |
Fujisawa Pharmaceutical Co., Ltd. |
Quinolizinone compounds and pharmaceutical composition comprising the same, useful as anti-ulcerative and anti-allergic agents
|
|
US4576942A
(en)
*
|
1984-07-12 |
1986-03-18 |
Usv Pharmaceutical Corp. |
Anti-allergic and anti-inflammatory bi- and tri- cyclo-1,4-thiazine derivatives, composition, and method of use therefor
|
|
US5173489A
(en)
|
1986-04-10 |
1992-12-22 |
The Dupont Merck Pharmaceutical Co. |
α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
|
|
US4760083A
(en)
|
1986-04-10 |
1988-07-26 |
E. I. Dupont De Nemours & Company |
3,3-disubstituted indolines
|
|
GB8621217D0
(en)
|
1986-09-03 |
1986-10-08 |
Ici Plc |
Chemical compounds
|
|
DE3805746C2
(de)
*
|
1987-03-05 |
2003-04-10 |
Clariant Finance Bvi Ltd |
1:2-Chromkomplexfarbstoffe
|
|
JPS63290821A
(ja)
|
1987-05-25 |
1988-11-28 |
Otsuka Pharmaceut Co Ltd |
抗不整脈剤
|
|
DK641487A
(da)
|
1987-12-07 |
1989-06-08 |
Gluetech Aps |
Fremgangsmaade til modificering af polymeroverflader
|
|
DE3807295A1
(de)
*
|
1988-03-05 |
1989-09-14 |
Basf Ag |
Neue n-heteroaryl-tetrahydrophthalimidverbindungen
|
|
JP2614081B2
(ja)
*
|
1988-05-27 |
1997-05-28 |
大塚化学株式会社 |
光学活性β−ラクタム誘導体の製造法
|
|
US5167941A
(en)
|
1988-11-29 |
1992-12-01 |
The Dow Chemical Company |
Quaternary polyamines as sulfite oxidation inhibitors in amine scrubbing of SO2
|
|
US5019365A
(en)
*
|
1988-11-29 |
1991-05-28 |
The Dow Chemical Company |
Quaternary polyamines as sulfite oxidation inhibitors
|
|
GB8901836D0
(en)
|
1989-01-27 |
1989-03-15 |
Sobio Lab |
Compounds
|
|
US5047554A
(en)
|
1989-04-18 |
1991-09-10 |
Pfizer Inc. |
3-substituted-2-oxindole derivatives
|
|
US5077142A
(en)
|
1989-04-20 |
1991-12-31 |
Ricoh Company, Ltd. |
Electroluminescent devices
|
|
WO1991000863A1
(en)
|
1989-07-07 |
1991-01-24 |
Pfizer Inc. |
Heteroaryl piperazine antipsychotic agents
|
|
JPH0343744A
(ja)
|
1989-07-12 |
1991-02-25 |
Hitachi Chem Co Ltd |
電子写真感光体
|
|
US5310562A
(en)
*
|
1989-11-22 |
1994-05-10 |
Margolin Solomon B |
Composition and method for reparation and prevention of fibrotic lesions
|
|
US5716632A
(en)
*
|
1989-11-22 |
1998-02-10 |
Margolin; Solomon B. |
Compositions and methods for reparation and prevention of fibrotic lesions
|
|
US5518729A
(en)
*
|
1989-11-22 |
1996-05-21 |
Margolin; Solomon B. |
Compositions and methods for reparation and prevention of fibrotic lesions
|
|
CA2078126A1
(en)
|
1990-03-27 |
1991-09-28 |
Jerry Leroy Adams |
5-lipoxygenase inhibitors
|
|
ATE180475T1
(de)
|
1990-09-21 |
1999-06-15 |
Rohm & Haas |
Dihydropyridazinone und pyridazinone als fungizide
|
|
JPH04223457A
(ja)
|
1990-12-26 |
1992-08-13 |
Konica Corp |
ハロゲン化銀写真感光材料
|
|
WO1992013451A1
(en)
*
|
1991-02-11 |
1992-08-20 |
Schering Agrochemicals Limited |
Imidazole pesticides
|
|
DE69222637T2
(de)
|
1991-05-10 |
1998-02-26 |
Rhone Poulenc Rorer Int |
Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase
|
|
RU2126255C1
(ru)
|
1991-05-15 |
1999-02-20 |
Йель Юниверсити |
Способ получения противоопухолевого эффекта у млекопитающих
|
|
EP0531578B1
(en)
|
1991-09-10 |
1995-12-20 |
Agfa-Gevaert N.V. |
Thermally transferable fluorescent compounds
|
|
ES2113399T3
(es)
|
1991-12-26 |
1998-05-01 |
Mitsubishi Chem Corp |
Derivados de beta-oxo-beta-bencenopropano-tio-amida.
|
|
US5241065A
(en)
*
|
1992-02-25 |
1993-08-31 |
Schering Corporation |
2,3,4,5-tetrahydro-1h-3-benzazepines having anti-psychotic activity
|
|
CA2118212A1
(en)
|
1992-04-16 |
1993-10-28 |
Matthew M. Abelman |
Substituted nitrogen containing spiro compounds for use in treating cognitive deficits
|
|
AU4376893A
(en)
|
1992-05-19 |
1993-12-13 |
Immunopharmaceutics, Inc. |
Compounds that modulate endothelin activity
|
|
DE4237656A1
(de)
*
|
1992-06-13 |
1993-12-16 |
Merck Patent Gmbh |
Benzimidazolderivate
|
|
US5457099A
(en)
|
1992-07-02 |
1995-10-10 |
Sawai Pharmaceutical Co., Ltd. |
Carbostyril derivatives and antiallergic agent
|
|
CA2099743A1
(en)
|
1992-07-02 |
1994-01-03 |
Akihiko Ishida |
Pyridazinone derivatives and processes for preparing the same
|
|
US5356904A
(en)
|
1992-10-07 |
1994-10-18 |
Merck & Co., Inc. |
Carbostyril oxytocin receptor antagonists
|
|
DE4242451A1
(de)
|
1992-12-16 |
1994-06-23 |
Basf Ag |
Verfahren zur Herstellung von 5-Ringheterocyclen
|
|
WO1994017059A1
(fr)
|
1993-01-29 |
1994-08-04 |
Nippon Soda Co., Ltd. |
Derive heterocyclique
|
|
JPH06256187A
(ja)
|
1993-03-02 |
1994-09-13 |
Fujisawa Pharmaceut Co Ltd |
キノリジノン化合物またはその塩を含有する鎮咳・去痰剤
|
|
ATE224712T1
(de)
|
1993-05-07 |
2002-10-15 |
Solomon B Margolin |
Zusammensetzungen und verfahren zur reparatur und vorbeugung fibrotischer verletzungen
|
|
JP3507124B2
(ja)
|
1993-05-26 |
2004-03-15 |
塩野義製薬株式会社 |
ベンジリデン誘導体の製造法
|
|
DE4423934A1
(de)
|
1993-09-02 |
1995-03-09 |
Basf Ag |
3(2H)-Pyridazinon-Derivate, Verfahren zu ihrer Herstellung und Verwendung
|
|
TW403741B
(en)
|
1993-10-15 |
2000-09-01 |
Takeda Chemical Industries Ltd |
Triazine derivative, production and use thereof
|
|
JPH07128793A
(ja)
|
1993-11-05 |
1995-05-19 |
Konica Corp |
染料の固体微粒子分散物および該分散物を含有するハロゲン化銀写真感光材料
|
|
CA2153498A1
(en)
*
|
1993-11-10 |
1995-05-18 |
Hidetsura Cho |
Chroman derivative and medicinal use thereof
|
|
EP0734398B1
(en)
|
1993-12-15 |
2002-02-27 |
Smithkline Beecham Corporation |
Compounds and methods
|
|
JPH07233072A
(ja)
|
1993-12-28 |
1995-09-05 |
Tanabe Seiyaku Co Ltd |
医薬組成物
|
|
CN1046724C
(zh)
|
1993-12-29 |
1999-11-24 |
藤泽药品工业株式会社 |
吡唑并吡啶化合物、含有它们的药物组合物、及其制法与用途
|
|
JP3781200B2
(ja)
|
1994-04-27 |
2006-05-31 |
コニカミノルタホールディングス株式会社 |
ハロゲン化銀写真感光材料の処理方法
|
|
JP3261641B2
(ja)
|
1994-04-28 |
2002-03-04 |
コニカ株式会社 |
ハロゲン化銀写真感光材料の処理方法
|
|
US5466697A
(en)
|
1994-07-13 |
1995-11-14 |
Syntex (U.S.A.) Inc. |
8-phenyl-1,6-naphthyridin-5-ones
|
|
JPH08134371A
(ja)
|
1994-11-02 |
1996-05-28 |
Konica Corp |
固体微粒子分散物及びハロゲン化銀写真感光材料及び画像形成方法
|
|
EP0717143A1
(de)
|
1994-12-16 |
1996-06-19 |
Lignozym GmbH |
Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung
|
|
US6323201B1
(en)
|
1994-12-29 |
2001-11-27 |
The Regents Of The University Of California |
Compounds for inhibition of ceramide-mediated signal transduction
|
|
US6114353A
(en)
*
|
1995-03-03 |
2000-09-05 |
Margolin; Solomon B. |
Compositions and method for treatment of lymphomas, leukemias, and leiomyomas
|
|
ES2220975T3
(es)
|
1995-03-03 |
2004-12-16 |
Solomon B. Margolin |
Tratamiento de trastornos producidos por factores de crecimiento de citoquina.
|
|
US6090822A
(en)
*
|
1995-03-03 |
2000-07-18 |
Margolin; Solomon B. |
Treatment of cytokine growth factor caused disorders
|
|
TW324008B
(en)
|
1995-03-13 |
1998-01-01 |
Ishihara Sangyo Kaisha |
Pyridone sulfonylurea compound, its production process and weed killer containing such compound
|
|
US5635494A
(en)
|
1995-04-21 |
1997-06-03 |
Rohm And Haas Company |
Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides
|
|
WO1996033994A1
(en)
|
1995-04-28 |
1996-10-31 |
Nippon Soda Co., Ltd. |
Amino-substituted derivatives, process for the preparation thereof, and herbicide
|
|
DE19520613A1
(de)
*
|
1995-06-06 |
1996-12-12 |
Bayer Ag |
Phenylpyridazinone
|
|
WO1997005109A1
(en)
|
1995-07-31 |
1997-02-13 |
Novo Nordisk A/S |
Heterocyclic compounds, their preparation and use
|
|
AU6514196A
(en)
|
1995-07-31 |
1997-02-26 |
Novo Nordisk A/S |
Heterocyclic compounds, their preparation and use
|
|
AR003978A1
(es)
|
1995-08-25 |
1998-09-30 |
Rohm & Haas |
Composiciones de acidos grasos y piridazinonas que tienen efectos fungitoxicos sinergicos y metodos para controlar hongos.
|
|
AU709178B2
(en)
|
1995-09-19 |
1999-08-26 |
Intermune, Inc. |
Inhibition of tumor necrosis factor alpha
|
|
US5962478A
(en)
|
1995-09-19 |
1999-10-05 |
Margolin; Solomon B. |
Inhibition of tumor necrosis factor α
|
|
DE19535501A1
(de)
*
|
1995-09-25 |
1997-03-27 |
Bayer Ag |
Pyridonmethidazofarbstoffe
|
|
JPH09249567A
(ja)
|
1996-01-12 |
1997-09-22 |
Otsuka Pharmaceut Co Ltd |
医薬組成物
|
|
JPH09204932A
(ja)
*
|
1996-01-25 |
1997-08-05 |
Fujitsu Ltd |
リチウム二次電池用電解液及びリチウム二次電池
|
|
IT1286545B1
(it)
|
1996-02-09 |
1998-07-15 |
Antonio Guarna |
Derivati benzo(c) chinolizinici,loro preparazione ed uso come inibitori delle 5-alfa-riduttasi
|
|
JPH09244235A
(ja)
|
1996-03-14 |
1997-09-19 |
Toshiba Corp |
アルカリ現像用レジスト
|
|
GB9607503D0
(en)
|
1996-04-11 |
1996-06-12 |
Merck Frosst Canada Inc |
Bisaryl cyclobutenes derivatives as cyclooxygenase inhibitors
|
|
ATE223376T1
(de)
|
1996-03-29 |
2002-09-15 |
Merck Frosst Canada Inc |
Bisarylcyclobutenderivate als cyclooxygenasehemmer
|
|
JPH09319023A
(ja)
|
1996-05-27 |
1997-12-12 |
Fuji Photo Film Co Ltd |
感熱記録材料
|
|
AU708883B2
(en)
*
|
1996-06-10 |
1999-08-12 |
Merck & Co., Inc. |
Substituted imidazoles having cytokine inhibitory activity
|
|
DE69707907T2
(de)
|
1996-09-26 |
2002-05-16 |
Syngenta Participations Ag, Basel |
Herbizid wirkende zusammensetzung
|
|
CA2216512A1
(en)
|
1996-10-11 |
1998-04-11 |
Rohm And Haas Company |
Dihydropyridazinones and pyridazinones their use as fungicides and insecticides
|
|
US5977134A
(en)
|
1996-12-05 |
1999-11-02 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
DE19754348A1
(de)
|
1996-12-11 |
1998-06-18 |
Ciba Geigy Ag |
Neue Herbizide
|
|
CA2276150A1
(en)
|
1996-12-30 |
1998-07-09 |
Steven D. Young |
Inhibitors of farnesyl-protein transferase
|
|
US5855654A
(en)
|
1997-01-30 |
1999-01-05 |
Rohm And Haas Company |
Pyridazinones as marine antifouling agents
|
|
US6117973A
(en)
|
1997-02-24 |
2000-09-12 |
Georgia Tech Research Corp. |
PNA monomers with electron donor or acceptor
|
|
DE19708928A1
(de)
*
|
1997-03-05 |
1998-09-10 |
Bayer Ag |
Substituierte aromatische Aminoverbindungen
|
|
WO1998051772A1
(de)
|
1997-05-12 |
1998-11-19 |
Call, Krimhild |
Enzymatisches bleichsystem mit neuen enzymwirkungsverstärkenden verbindungen
|
|
DE19821263A1
(de)
|
1997-05-12 |
1998-11-19 |
Call Krimhild |
Enzymatisches Bleichsystem mit enzymwirkungsverstärkenden Verbindungen zur Behandlung von Textilien
|
|
DE19726241A1
(de)
|
1997-06-20 |
1998-12-24 |
Call Krimhild |
Erweitertes enzymatisches Multikomponentensystem zur Behandlung von Abwässern, zur Herstellung von Holzverbundstoffen, zum Deinken von Altpapier, Colour stripping von Altpapier, zum Einsatz als Oxidationssystem bei der organischen Synthese und zum Einsatz bei der Kohleverflüssigung
|
|
DE19729061A1
(de)
|
1997-07-08 |
1999-01-14 |
Agfa Gevaert Ag |
Farbfotografisches Aufzeichnungsmaterial
|
|
SE9702651D0
(sv)
|
1997-07-09 |
1997-07-09 |
Astra Pharma Prod |
Novel compounds
|
|
DE19731784A1
(de)
|
1997-07-24 |
1999-02-04 |
Bayer Ag |
Substituierte N-Aryl-N-thioxocarbonyl-sulfonamide
|
|
SE9702794D0
(sv)
|
1997-07-24 |
1997-07-24 |
Astra Pharma Prod |
New compounds
|
|
JPH1149755A
(ja)
|
1997-07-30 |
1999-02-23 |
Nippon Kayaku Co Ltd |
新規含窒素ヘテロ環誘導体およびそれを有効成分とする殺虫殺ダニ組成物
|
|
ITFI970193A1
(it)
|
1997-08-01 |
1999-02-01 |
Applied Research Systems |
Uso di derivati benzo(c) chinolizinici come regolatori della crescita delle piante e composizioni ad uso agricolo che contengono tali
|
|
JP2002511887A
(ja)
|
1997-08-22 |
2002-04-16 |
アボツト・ラボラトリーズ |
プロスタグランジンエンドペルオキシドhシンターゼ生合成阻害薬
|
|
US6307047B1
(en)
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
|
EP1007515A1
(en)
|
1997-08-22 |
2000-06-14 |
Abbott Laboratories |
Arylpyridazinones as prostaglandin endoperoxide h synthase biosynthesis inhibitors
|
|
WO1999012903A1
(en)
|
1997-09-09 |
1999-03-18 |
Du Pont Pharmaceuticals Company |
Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor xa
|
|
AU749237B2
(en)
|
1997-10-27 |
2002-06-20 |
Isk Americas Incorporated |
Substituted benzene compounds, process for their preparation, and herbicidal and defolient compositions containing them
|
|
ES2172939T3
(es)
|
1997-11-21 |
2002-10-01 |
Astrazeneca Uk Ltd |
Nuevos compuestos que son antagonistas de receptores acoplados a proteina g de 7-transmembrana (tm) de p2-purinoceptores.
|
|
JPH11180952A
(ja)
|
1997-12-19 |
1999-07-06 |
Maruho Co Ltd |
2−オキシインドール誘導体
|
|
US6174901B1
(en)
*
|
1998-12-18 |
2001-01-16 |
Amgen Inc. |
Substituted pyridine and pyridazine compounds and methods of use
|
|
SI1042293T1
(sl)
|
1997-12-19 |
2008-08-31 |
Amgen Inc |
Substituirane piridinske in piridazinske spojine in njihova farmacevtska uporaba
|
|
DE19803667A1
(de)
|
1998-01-30 |
1999-08-05 |
Max Planck Gesellschaft |
Verfahren zur Herstellung von 5-Alkoxy (bzw. 5-Aroxy) -2,3-dihydrofuran-2-onen
|
|
FR2774986A1
(fr)
|
1998-02-16 |
1999-08-20 |
Rhodia Chimie Sa |
Utilisation de pyrone(s) ou equivalent pour masquer des isocyanates, procede de masquage, isocyanates ainsi masques, composition en contenant, procede de revetement utilisant ces compositions, revetement aini obtenu
|
|
ATE266405T1
(de)
|
1998-03-17 |
2004-05-15 |
Solomon B Margolin |
Topische antiseptische zusammenstellungen und methoden
|
|
PL343112A1
(en)
|
1998-03-31 |
2001-07-30 |
Warner Lambert Co |
Quinolones as serine protease inhibitors
|
|
JP2002511452A
(ja)
|
1998-04-09 |
2002-04-16 |
バイエル アクチェンゲゼルシャフト |
置換フェニルピリダジノン類
|
|
AU3536699A
(en)
*
|
1998-04-27 |
1999-11-16 |
Ihara Chemical Industry Co. Ltd. |
3-arylphenyl sulfide derivatives and insecticides and miticides
|
|
CZ20003978A3
(cs)
|
1998-04-27 |
2001-09-12 |
Centre National De La Recherche Scientifique |
Deriváty 3-(amino- nebo aminoalkyl) pyridinonu a jejich použití
|
|
AU754094B2
(en)
*
|
1998-06-01 |
2002-11-07 |
Astellas Pharma Inc. |
Remedies for male sterility
|
|
FR2779429B1
(fr)
|
1998-06-03 |
2000-07-13 |
Synthelabo |
Derives d'oxindole, leurs preparations et leurs applications en therapeutique
|
|
DE19826671A1
(de)
*
|
1998-06-16 |
1999-12-23 |
Hoechst Schering Agrevo Gmbh |
1,3-Oxazolin- und 1,3-Thiazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
|
|
WO2000016775A1
(en)
|
1998-09-18 |
2000-03-30 |
Mepha Ag |
Topical formulation of alkyl-, phenyl-pyridone
|
|
AU1230100A
(en)
|
1998-10-29 |
2000-05-22 |
Merck & Co., Inc. |
A method of treating endometriosis
|
|
US6586447B1
(en)
*
|
1999-04-01 |
2003-07-01 |
Pfizer Inc |
3,3-disubstituted-oxindole derivatives useful as anticancer agents
|
|
DE19918725A1
(de)
|
1999-04-24 |
2000-10-26 |
Bayer Ag |
Substituierte N-Cyano-sulfonsäureanilide
|
|
SK288186B6
(sk)
|
1999-05-07 |
2014-05-06 |
Encysive Pharmaceuticals, Inc. |
Deriváty kyseliny propiónovej, ktoré inhibujú väzbu integrínov na ich receptory, farmaceutické kompozície s ich obsahom a ich použitie
|
|
US6972296B2
(en)
|
1999-05-07 |
2005-12-06 |
Encysive Pharmaceuticals Inc. |
Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
|
|
US6723711B2
(en)
|
1999-05-07 |
2004-04-20 |
Texas Biotechnology Corporation |
Propanoic acid derivatives that inhibit the binding of integrins to their receptors
|
|
WO2001012600A1
(en)
|
1999-08-12 |
2001-02-22 |
Cor Therapeutics, Inc. |
INHIBITORS OF FACTOR Xa
|
|
FR2797629B1
(fr)
|
1999-08-19 |
2001-09-21 |
Rhodia Chimie Sa |
Utilisation de pyrone(s) ou equivalent pour masquer des isocyanates, procede de masquage, isocyanates ainsi masques, composition en contenant, procede de revetement utilisant ces compositions, revetement ainsi obtenu
|
|
AT408223B
(de)
*
|
1999-12-27 |
2001-09-25 |
Dsm Fine Chem Austria Gmbh |
Verfahren zur herstellung von oxindolen
|
|
IL150650A0
(en)
|
2000-01-20 |
2003-02-12 |
Eisai Co Ltd |
Piperidine derivatives and pharmaceutical compositions containing the same
|
|
AU2001234690A1
(en)
|
2000-02-01 |
2001-08-14 |
Cor Therapeutics, Inc. |
2-(1h)-quinolone and 2-(1h)-quinoxalone inhibitors of factor xa
|
|
AU2001234705A1
(en)
|
2000-02-01 |
2001-08-14 |
Cor Therapeutics, Inc. |
Indalone and benzimidazolone inhibitors of factor xa
|
|
WO2001057037A1
(en)
|
2000-02-04 |
2001-08-09 |
Cor Therapeutics, Inc. |
Platelet adp receptor inhibitors
|
|
US6906063B2
(en)
*
|
2000-02-04 |
2005-06-14 |
Portola Pharmaceuticals, Inc. |
Platelet ADP receptor inhibitors
|
|
GB0002740D0
(en)
|
2000-02-07 |
2000-03-29 |
Novartis Ag |
Organic compounds
|
|
AU2001230605A1
(en)
|
2000-02-09 |
2001-08-20 |
Shionogi And Co., Ltd. |
Apoptosis inhibitor
|
|
WO2001062253A1
(en)
|
2000-02-21 |
2001-08-30 |
Cymar, Inc. |
Compositions and methods for treatment of epilepsy
|
|
AU2001239550A1
(en)
|
2000-03-23 |
2001-10-03 |
Takeda Chemical Industries Ltd. |
Furoisoquinoline derivatives, process for producing the same and use thereof
|
|
US6548517B2
(en)
|
2000-03-24 |
2003-04-15 |
Millennium Pharmaceuticals, Inc. |
Oxindole inhibitors of factor Xa
|
|
DE10024938A1
(de)
|
2000-05-19 |
2001-11-22 |
Bayer Ag |
Substituierte Iminoazine
|
|
US20030194748A1
(en)
|
2000-05-29 |
2003-10-16 |
Tohru Nagasaki |
Method for labeling with tritium
|
|
WO2001096308A1
(en)
*
|
2000-06-12 |
2001-12-20 |
Eisai Co., Ltd. |
1,2-dihydropyridine compounds, process for preparation of the same and use thereof
|
|
DE10034803A1
(de)
|
2000-07-18 |
2002-01-31 |
Bayer Ag |
Substituierte Sulfonsäureanilide
|
|
HUP0700086A2
(en)
*
|
2000-08-11 |
2007-05-29 |
Eisai Co Ltd |
2-aminopyridine compounds, use thereof as drugs and pharmaceutical compositions containing them
|
|
US20020049211A1
(en)
|
2000-09-06 |
2002-04-25 |
Sobolov-Jaynes Susan Beth |
Combination treatment for depression and anxiety
|
|
JP4233868B2
(ja)
|
2000-09-18 |
2009-03-04 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
ピリダジノンおよびトリアジノン化合物類ならびにそれらの医薬用途
|
|
ATE319706T1
(de)
|
2000-09-19 |
2006-03-15 |
Centre Nat Rech Scient |
Pyridinon und pyridinethion-derivate mit hiv- hemmenden eigenschaften
|
|
CN1120151C
(zh)
|
2000-10-24 |
2003-09-03 |
大连化学工业股份有限公司 |
制备内酰胺的方法
|
|
AU2001297622A1
(en)
|
2000-10-27 |
2002-09-12 |
Dow Agrosciences Llc |
Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides and insecticides
|
|
EP1343763A1
(en)
|
2000-11-20 |
2003-09-17 |
Bristol-Myers Squibb Company |
Pyrodone derivatives as ap2 inhibitors
|
|
US7160912B2
(en)
*
|
2000-12-26 |
2007-01-09 |
Dr.Reddy's Laboratories Ltd. |
Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them
|
|
YU52403A
(sh)
*
|
2000-12-26 |
2006-03-03 |
Dr.Reddy's Research Foundation |
Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
|
|
DE60139506D1
(de)
*
|
2000-12-28 |
2009-09-17 |
Shionogi & Co |
2-pyridonderivate mit affinität für den cannabinoid-typ-2-rezeptor
|
|
DE60234812D1
(de)
|
2001-01-29 |
2010-02-04 |
Shionogi & Co |
Arzneipräparat, das als wirkstoff 5-methyl-1-phenyl-2-(1h)-pyridon enthält
|
|
DE10108995A1
(de)
|
2001-02-23 |
2002-09-05 |
Abbott Gmbh & Co Kg |
Substituierte Pyrimidinon-Derivate als Liganden von Integrinrezeptoren
|
|
JPWO2002085858A1
(ja)
|
2001-04-20 |
2004-08-12 |
旭硝子株式会社 |
精製されたピペリジン誘導体の製造方法
|
|
WO2002090334A1
(en)
|
2001-05-08 |
2002-11-14 |
Kudos Pharmaceuticals Limited |
Isoquinolinone derivatives as parp inhibitors
|
|
AU2002316180A1
(en)
|
2001-06-01 |
2002-12-16 |
The Regents Of The University Of California |
Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction
|
|
JP2002371078A
(ja)
|
2001-06-12 |
2002-12-26 |
Sankyo Co Ltd |
キノリン誘導体及びキノロン誘導体
|
|
JP4180254B2
(ja)
|
2001-06-29 |
2008-11-12 |
独立行政法人科学技術振興機構 |
窒素含有6員環の製造方法
|
|
JP2003021901A
(ja)
*
|
2001-07-05 |
2003-01-24 |
Fuji Photo Film Co Ltd |
感光性平版印刷版の光重合方法
|
|
KR100898888B1
(ko)
|
2001-08-06 |
2009-05-21 |
시오노기세이야쿠가부시키가이샤 |
5-메틸-1-페닐-2(1h)피리디논의 제조 방법
|
|
WO2003035650A1
(en)
|
2001-09-25 |
2003-05-01 |
Takeda Chemical Industries, Ltd. |
Entry inhibitor
|
|
GB0124848D0
(en)
|
2001-10-16 |
2001-12-05 |
Celltech R&D Ltd |
Chemical compounds
|
|
TWI301834B
(en)
|
2001-10-22 |
2008-10-11 |
Eisai R&D Man Co Ltd |
Pyrimidone compound and pharmaceutical composition including the same
|
|
TWI330183B
(enExample)
*
|
2001-10-22 |
2010-09-11 |
Eisai R&D Man Co Ltd |
|
|
CN1257901C
(zh)
|
2001-11-08 |
2006-05-31 |
中国科学院上海药物研究所 |
一类四氢喹啉酮哌啶类化合物及其制备方法和用途
|
|
US7030141B2
(en)
|
2001-11-29 |
2006-04-18 |
Christopher Franklin Bigge |
Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
|
|
GB0129260D0
(en)
|
2001-12-06 |
2002-01-23 |
Eisai London Res Lab Ltd |
Pharmaceutical compositions and their uses
|
|
GB0129391D0
(en)
|
2001-12-07 |
2002-01-30 |
Syngenta Participations Ag |
Microbiocidal n-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives
|
|
JP2005170790A
(ja)
|
2002-01-09 |
2005-06-30 |
Ajinomoto Co Inc |
N−アルキルスルフォニル置換アミド誘導体
|
|
JP2005519895A
(ja)
|
2002-01-18 |
2005-07-07 |
ファルマシア・コーポレーション |
P38阻害剤としての置換ピリダジノン
|
|
AP1822A
(en)
|
2002-02-14 |
2008-01-30 |
Pharmacia Corp |
Substituted pyridinones as modulators of P38 MAP kinase.
|
|
JP2003238611A
(ja)
|
2002-02-18 |
2003-08-27 |
Japan Polyolefins Co Ltd |
オレフィン類重合用触媒成分、オレフィン類重合用触媒及びポリオレフィン類の製造方法
|
|
WO2003070277A1
(en)
*
|
2002-02-19 |
2003-08-28 |
Shionogi & Co., Ltd. |
Antipruritics
|
|
JP2003261535A
(ja)
|
2002-03-08 |
2003-09-19 |
Mitsubishi Chemicals Corp |
2−ヒドロキシ−5−メチルピリジンの製造方法
|
|
IL163957A0
(en)
*
|
2002-03-14 |
2005-12-18 |
Bayer Healthcare Ag |
Monocyclic aroylpyridinones as antiinflammatory agents
|
|
WO2003082265A2
(en)
|
2002-04-02 |
2003-10-09 |
Fujisawa Pharmaceutical Co |
Pharmaceutical composition for treating or preventing virus infectious diseases
|
|
GB0210127D0
(en)
|
2002-05-02 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2484631A1
(en)
|
2002-05-13 |
2003-11-27 |
Merck & Co., Inc. |
Phenyl substituted imidazopyridines and phenyl substituted benzimidazoles
|
|
CN1218942C
(zh)
|
2002-06-11 |
2005-09-14 |
中南大学湘雅医学院 |
抗纤维化吡啶酮化合物及其生产工艺方法
|
|
WO2003106452A2
(en)
|
2002-06-12 |
2003-12-24 |
Millennium Pharmaceuticals, Inc. |
Antagonists of melanin concentrating hormone receptor
|
|
US20040006135A1
(en)
|
2002-06-19 |
2004-01-08 |
Pfizer Inc. |
Combination treatment for depression and anxiety
|
|
GB0214268D0
(en)
|
2002-06-20 |
2002-07-31 |
Celltech R&D Ltd |
Chemical compounds
|
|
GB0215293D0
(en)
|
2002-07-03 |
2002-08-14 |
Rega Foundation |
Viral inhibitors
|
|
WO2004006906A2
(en)
|
2002-07-15 |
2004-01-22 |
Combinatorx, Incorporated |
Methods for the treatment of neoplasms
|
|
WO2004009560A1
(en)
|
2002-07-22 |
2004-01-29 |
Orchid Chemicals & Pharmaceuticals Ltd |
Novel bio-active molecules
|
|
AU2003255149A1
(en)
|
2002-07-24 |
2004-02-09 |
Kyorin Pharmaceutical Co., Ltd. |
4-(substituted aryl)-5-hydroxyisoquinolinone derivative
|
|
GB0218630D0
(en)
|
2002-08-10 |
2002-09-18 |
Tanabe Seiyaku Co |
Novel compounds
|
|
MXPA05001603A
(es)
|
2002-08-13 |
2005-04-25 |
Warner Lambert Co |
Derivados monociclicos como inhibidores de metaloproteinasa de matriz.
|
|
WO2004019863A2
(en)
|
2002-08-28 |
2004-03-11 |
Intermune, Inc. |
Combination therapy for treatment of fibrotic disorders
|
|
WO2004024078A2
(en)
|
2002-09-11 |
2004-03-25 |
Merck & Co., Inc. |
Dihydroxypyridopyrazine-1,6-dione compounds useful as hiv integrase inhibitors
|
|
CH696420A5
(de)
|
2002-09-13 |
2007-06-15 |
Mepha Ag |
Neue stabile Zubereitungen von Alkyl-, Phenyl-Pyridonen für topische Anwendung.
|
|
EP1400243A1
(en)
|
2002-09-19 |
2004-03-24 |
Tanabe Seiyaku Co., Ltd. |
Calcium-activated K channel activator
|
|
GB0222743D0
(en)
*
|
2002-10-01 |
2002-11-06 |
Celltech R&D Ltd |
Chemical compounds
|
|
WO2004031145A2
(en)
|
2002-10-02 |
2004-04-15 |
Bristol-Myers Squibb Company |
Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor xa inhibitors
|
|
WO2004037159A2
(en)
|
2002-10-23 |
2004-05-06 |
Obetherapy Biotechnology |
Compounds, compositions and methods for modulating fat metabolism
|
|
US6930117B2
(en)
*
|
2002-11-09 |
2005-08-16 |
The Procter & Gamble Company |
N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
|
|
AR042206A1
(es)
|
2002-11-26 |
2005-06-15 |
Novartis Ag |
Acidos fenilaceticos y derivados
|
|
JP4542743B2
(ja)
|
2002-12-26 |
2010-09-15 |
Kdl株式会社 |
ピリドン誘導体の溶液状医薬組成物
|
|
US7202257B2
(en)
*
|
2003-12-24 |
2007-04-10 |
Deciphera Pharmaceuticals, Llc |
Anti-inflammatory medicaments
|
|
US7144911B2
(en)
*
|
2002-12-31 |
2006-12-05 |
Deciphera Pharmaceuticals Llc |
Anti-inflammatory medicaments
|
|
US20040142950A1
(en)
*
|
2003-01-17 |
2004-07-22 |
Bunker Amy Mae |
Amide and ester matrix metalloproteinase inhibitors
|
|
US7582641B2
(en)
|
2003-01-31 |
2009-09-01 |
Vertex Pharmaceuticals Incorporated |
Gyrase inhibitors and uses thereof
|
|
US7618974B2
(en)
*
|
2003-01-31 |
2009-11-17 |
Vertex Pharmaceuticals Incorporated |
Gyrase inhibitors and uses thereof
|
|
AR042956A1
(es)
|
2003-01-31 |
2005-07-13 |
Vertex Pharma |
Inhibidores de girasa y usos de los mismos
|
|
US7569591B2
(en)
*
|
2003-01-31 |
2009-08-04 |
Vertex Pharmaceuticals Incorporated |
Gyrase inhibitors and uses thereof
|
|
CL2004000234A1
(es)
|
2003-02-12 |
2005-04-15 |
Biogen Idec Inc |
Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
|
|
US20040157738A1
(en)
*
|
2003-02-12 |
2004-08-12 |
Ishihara Sangyo Kaisha, Ltd. |
Novel oxygen containing fused cyclic derivatives and herbicidal, desiccant and defoliate compositions containing them
|
|
CA2515939A1
(en)
|
2003-02-14 |
2004-09-02 |
Smithkline Beecham Corporation |
Novel compounds
|
|
US7012088B2
(en)
|
2003-02-24 |
2006-03-14 |
Pharmacia & Upjohn Company |
Indolone oxazolidinones and derivatives thereof
|
|
AU2004218474A1
(en)
|
2003-02-28 |
2004-09-16 |
Dekk-Tec, Inc. |
Resonance modulator for diagnosis and therapy
|
|
WO2005013917A2
(en)
|
2003-02-28 |
2005-02-17 |
Intermune, Inc. |
Combination therapy for treating alphavirus infection and liver fibrosis
|
|
JP2004269469A
(ja)
|
2003-03-12 |
2004-09-30 |
Yamanouchi Pharmaceut Co Ltd |
ピリミジン誘導体又はその塩
|
|
WO2004089914A1
(de)
*
|
2003-04-08 |
2004-10-21 |
Basf Aktiengesellschaft |
Benzolsulfonamid-derivate als herbizide oder desikkante/defoliante verbindungen
|
|
JP4089491B2
(ja)
|
2003-04-14 |
2008-05-28 |
コニカミノルタホールディングス株式会社 |
重合開始剤、重合組成物、ラジカル発生方法、平版印刷版材料および平版印刷版の作製方法
|
|
US20070032457A1
(en)
|
2003-05-16 |
2007-02-08 |
Blatt Lawrence M |
Combination therapy for cancer treatment
|
|
WO2004103296A2
(en)
*
|
2003-05-16 |
2004-12-02 |
Intermune, Inc. |
Methods of treating idiopathic pulmonary fibrosis
|
|
WO2004105684A2
(en)
|
2003-05-16 |
2004-12-09 |
Intermune, Inc. |
Combination therapy for proliferative disorders
|
|
JP2004359641A
(ja)
|
2003-06-06 |
2004-12-24 |
Ono Pharmaceut Co Ltd |
Ccr5活性化剤
|
|
WO2005000227A2
(en)
|
2003-06-06 |
2005-01-06 |
Intermune, Inc. |
Methods of treating tnf-mediated disorders
|
|
AU2004249495A1
(en)
|
2003-06-20 |
2004-12-29 |
Ucb Pharma S.A. |
Thienopyridone derivatives as kinase inhibitors
|
|
CA2528603A1
(en)
|
2003-06-20 |
2004-12-29 |
Celltech R & D Limited |
Thienopyridone derivatives as kinase inhibitors
|
|
WO2005000818A1
(en)
|
2003-06-27 |
2005-01-06 |
Warner-Lambert Company Llc |
5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
|
|
JP4667241B2
(ja)
*
|
2003-06-27 |
2011-04-06 |
旭化成株式会社 |
細胞分化抑制剤、これを用いた細胞培養方法、培養液及び培養された細胞株
|
|
JP2005013152A
(ja)
|
2003-06-27 |
2005-01-20 |
Asahi Kasei Corp |
細胞分化抑制剤及びこれを用いた細胞培養方法、培養液、培養された細胞
|
|
US20050096256A1
(en)
|
2003-07-01 |
2005-05-05 |
President And Fellows Of Harvard College |
Compositions for manipulating the lifespan and stress response of cells and organisms
|
|
US20060025337A1
(en)
*
|
2003-07-01 |
2006-02-02 |
President And Fellows Of Harvard College |
Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
|
|
WO2005007632A1
(en)
|
2003-07-18 |
2005-01-27 |
Pharmacia Corporation |
Substituted pyridazinones as inhibitors of p38
|
|
BRPI0413234A
(pt)
|
2003-08-01 |
2006-10-03 |
Genelabs Tech Inc |
derivados de imidazola bicìclica contra flaviviridae
|
|
CL2004002050A1
(es)
|
2003-08-13 |
2005-06-03 |
Pharmacia Corp Sa Organizada B |
Compuestos derivados de piridinonas sustituidas; su uso en el tratamiento de afecciones causadas o exacerbadas por actividad p38 map kinasa y/o tnf no regulada, tales como inflamaciones, tumores, sida y otros.
|
|
WO2005023246A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Aventis Pharmaceuticals Inc. |
Substituted indoles as inhibitors of poly (adp-ribose) polymerase (parp)
|
|
US20050065144A1
(en)
*
|
2003-09-08 |
2005-03-24 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
SE0302486D0
(sv)
|
2003-09-18 |
2003-09-18 |
Astrazeneca Ab |
Novel compounds
|
|
SE0302487D0
(sv)
|
2003-09-18 |
2003-09-18 |
Astrazeneca Ab |
Novel compounds
|
|
DE10345648A1
(de)
|
2003-10-01 |
2005-04-21 |
Studiengesellschaft Kohle Mbh |
Verfahren zur Herstellung von TMC-69-6H und verwandten Pyridonderivaten und deren Verwendung als Phosphatase-Inhibitoren
|
|
WO2005040758A2
(en)
*
|
2003-10-24 |
2005-05-06 |
Intermune, Inc. |
Use of pirfenidone in therapeutic regimens
|
|
WO2005039598A1
(en)
|
2003-10-24 |
2005-05-06 |
Intermune, Inc. |
Method of treating alcoholic liver disease
|
|
US7825133B2
(en)
*
|
2003-11-14 |
2010-11-02 |
Shanghai Genomics, Inc. |
Derivatives of pyridone and the use of them
|
|
JP4170198B2
(ja)
|
2003-11-14 |
2008-10-22 |
一丸ファルコス株式会社 |
化粧料組成物
|
|
US7732616B2
(en)
*
|
2003-11-19 |
2010-06-08 |
Array Biopharma Inc. |
Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof
|
|
KR101190912B1
(ko)
|
2003-11-19 |
2012-10-12 |
어레이 바이오파마 인크. |
Mek의 헤테로시클릭 억제제 및 그의 사용 방법
|
|
US7517994B2
(en)
|
2003-11-19 |
2009-04-14 |
Array Biopharma Inc. |
Heterocyclic inhibitors of MEK and methods of use thereof
|
|
WO2005051949A1
(ja)
|
2003-11-26 |
2005-06-09 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規縮合イミダゾール誘導体
|
|
WO2005053707A1
(ja)
|
2003-12-05 |
2005-06-16 |
Ono Pharmaceutical Co., Ltd. |
馬尾神経組織血流増加剤
|
|
DE10358004A1
(de)
*
|
2003-12-11 |
2005-07-14 |
Abbott Gmbh & Co. Kg |
Ketolactam-Verbindungen und ihre Verwendung
|
|
US20070191336A1
(en)
*
|
2003-12-24 |
2007-08-16 |
Flynn Daniel L |
Anti-inflammatory medicaments
|
|
CA2555258C
(en)
|
2004-01-29 |
2009-04-28 |
Pfizer Inc. |
1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide derivatives having 5-ht4 receptor agonistic activity
|
|
GB0402812D0
(en)
|
2004-02-09 |
2004-03-10 |
Tanabe Seiyaku Co |
Novel compounds
|
|
JP2005255675A
(ja)
|
2004-02-09 |
2005-09-22 |
Tanabe Seiyaku Co Ltd |
医薬組成物
|
|
EP1742905A2
(en)
|
2004-02-20 |
2007-01-17 |
Japan Science and Technology Agency |
Process of making alfa-aminooxyketone/ alfa-aminooxyaldehyde and alfa-hydroxyketone/ alfa-hydroxyaldehyde compounds and a process of making reaction products from cyclic alfa, beta-unsaturated ketone substrates and nitroso substrates
|
|
US7732456B2
(en)
|
2004-03-05 |
2010-06-08 |
Banyu Pharmaceutical Co., Ltd. |
Pyridone derivative
|
|
PE20060285A1
(es)
|
2004-03-30 |
2006-05-08 |
Aventis Pharma Inc |
Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)
|
|
JP4790703B2
(ja)
|
2004-04-07 |
2011-10-12 |
武田薬品工業株式会社 |
環式化合物
|
|
AU2005231507B2
(en)
|
2004-04-08 |
2012-03-01 |
Targegen, Inc. |
Benzotriazine inhibitors of kinases
|
|
JPWO2005105743A1
(ja)
*
|
2004-04-28 |
2008-03-13 |
小野薬品工業株式会社 |
含窒素複素環化合物およびその医薬用途
|
|
MY143245A
(en)
|
2004-04-28 |
2011-04-15 |
Mitsubishi Tanabe Pharma Corp |
4- 2-(cycloalkylamino)pyrimidin-4-yl-(phenyl)-imidazolin-2-one derivatives as p38 map-kinase inhibitors for the treatment of inflammatory diseases
|
|
DE102004028973A1
(de)
|
2004-06-16 |
2006-01-05 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte Tetrahydro-2H-isochinolin-1-on-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
|
|
KR101195801B1
(ko)
*
|
2004-06-18 |
2012-11-05 |
밀레니엄 파머슈티컬스 인코퍼레이티드 |
Xa 인자 억제제
|
|
US7696352B2
(en)
|
2004-06-18 |
2010-04-13 |
Millennium Pharmaceuticals, Inc. |
Factor Xa inhibitors
|
|
MY148809A
(en)
*
|
2004-07-06 |
2013-05-31 |
Eisai R&D Man Co Ltd |
Crystals of 1,2-dihydropyridine compound and their production process
|
|
WO2006011024A2
(en)
|
2004-07-19 |
2006-02-02 |
Glenmark Pharmaceuticals Ltd. |
New tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
|
|
JP5704785B2
(ja)
|
2004-07-19 |
2015-04-22 |
ザ・ジョンズ・ホプキンス・ユニバーシティ |
免疫抑制のためのflt3阻害剤
|
|
MX2007001399A
(es)
|
2004-08-02 |
2007-04-18 |
Osi Pharm Inc |
Compuestos que inhiben pirrolopirimidina multi-cinasa aril-amino sustituidas.
|
|
EP1786803A1
(en)
|
2004-08-31 |
2007-05-23 |
Biogen Idec MA, Inc. |
Pyrimidinylpyrazoles as tgf-beta inhibitors
|
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
MX2007003375A
(es)
|
2004-09-22 |
2007-05-07 |
Janssen Pharmaceutica Nv |
Inhibidores de la interaccion entre mdm2 y p53.
|
|
US20060069260A1
(en)
*
|
2004-09-28 |
2006-03-30 |
Huiping Zhang |
Preparation of N-aryl pyridones
|
|
WO2006038734A1
(en)
|
2004-10-08 |
2006-04-13 |
Astellas Pharma Inc. |
Pyridazinone derivatives cytokines inhibitors
|
|
NZ554493A
(en)
|
2004-10-12 |
2009-09-25 |
Decode Genetics Ehf |
Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease
|
|
TWI360539B
(en)
|
2004-10-28 |
2012-03-21 |
Shionogi & Co |
3-carbamoyl-2-pyridone derivatives
|
|
US7713998B2
(en)
|
2004-11-10 |
2010-05-11 |
Ono Pharmaceutical Co., Ltd. |
Nitrogenous heterocyclic compound and pharmaceutical use thereof
|
|
JP2006142666A
(ja)
|
2004-11-19 |
2006-06-08 |
Mitsubishi Chemicals Corp |
光学記録媒体用色素
|
|
US20060206269A1
(en)
|
2004-11-19 |
2006-09-14 |
Pharmacopeia Drug Discovery, Inc. |
One-dimensional QSAR models
|
|
CA2587853A1
(en)
*
|
2004-11-23 |
2006-06-01 |
Wyeth |
Gonadotropin releasing hormone receptor antagonists
|
|
WO2006057961A1
(en)
|
2004-11-24 |
2006-06-01 |
Vertex Pharmaceuticals Incorporated |
3-[2-(3-acylamino-2-oxo-2h-pyridin-1-yl)-acetylamino]-4-oxo-pentanoic acid derivatives and their use as caspase inhibitors
|
|
EP1838675A1
(en)
|
2004-11-24 |
2007-10-03 |
Laboratoires Serono S.A. |
Novel 4-arylamino pyridone derivatives as mek inhibitors for the treatment of hyperproliferative disorders
|
|
JP2008521805A
(ja)
|
2004-11-30 |
2008-06-26 |
アーテシアン セラピューティクス, インコーポレイテッド |
β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
|
|
WO2006059778A1
(ja)
|
2004-12-01 |
2006-06-08 |
Banyu Pharmaceutical Co., Ltd. |
置換ピリドン誘導体
|
|
AP2007004040A0
(en)
|
2004-12-17 |
2007-06-30 |
Anadys Pharmaceuticals Inc |
Pyridazinone compounds
|
|
EP1845092B1
(en)
|
2004-12-23 |
2010-09-01 |
Hui Yao |
Pyrimidinone compounds, their preparation and use thereof
|
|
US20060148842A1
(en)
|
2004-12-29 |
2006-07-06 |
Scialdone Mark A |
Nepetalactams and N-substituted derivatives thereof
|
|
WO2006072037A1
(en)
|
2004-12-29 |
2006-07-06 |
E. I. Du Pont De Nemours And Company |
Dihydronepetalactams and n-substituted derivatives thereof
|
|
AU2006204699B2
(en)
|
2005-01-13 |
2012-04-26 |
Sirtris Pharmaceuticals, Inc. |
Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders
|
|
AU2006206274A1
(en)
|
2005-01-20 |
2006-07-27 |
Sirtris Pharmaceuticals, Inc. |
Use of sirtuin-activating compounds for treating flushing and drug induced weight gain
|
|
US7582634B2
(en)
*
|
2005-02-18 |
2009-09-01 |
Wyeth |
7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
|
|
US7534796B2
(en)
*
|
2005-02-18 |
2009-05-19 |
Wyeth |
Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
|
|
CN1676518B
(zh)
|
2005-03-17 |
2010-05-12 |
南开大学 |
4-取代苯基哒嗪类化合物及除草活性
|
|
JP5180816B2
(ja)
|
2005-04-04 |
2013-04-10 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
神経変性疾患および認知症のためのジヒドロピリジン化合物
|
|
RU2007141401A
(ru)
*
|
2005-04-08 |
2009-05-20 |
ЭЙСАЙ Ар энд Ди МЕНЕДЖМЕНТ КО., ЛТД. (JP) |
Терапевтический агент для лечения дискинезии
|
|
CN1846699A
(zh)
|
2005-04-13 |
2006-10-18 |
中南大学湘雅医院 |
1-(取代苯基)-5-甲基-2-(1h) 吡啶酮(i)化合物用于制备抗除肾间质纤维化外其他器官纤维化或组织纤维化药物的应用
|
|
JO2787B1
(en)
|
2005-04-27 |
2014-03-15 |
امجين إنك, |
Alternative amide derivatives and methods of use
|
|
KR20080007645A
(ko)
|
2005-04-28 |
2008-01-22 |
베링거 인겔하임 인터내셔날 게엠베하 |
염증성 질환 치료용 신규 화합물
|
|
AP2007004244A0
(en)
*
|
2005-05-10 |
2007-12-31 |
Intermune Inc |
Method of modulating stress-activated protein kinase system
|
|
GB0511190D0
(en)
|
2005-06-01 |
2005-07-06 |
Sterix Ltd |
Use
|
|
CA2610400A1
(en)
|
2005-06-07 |
2006-12-14 |
Pharmacopeia, Inc. |
Azinone and diazinone v3 inhibitors for depression and stress disorders
|
|
AU2006255084A1
(en)
|
2005-06-08 |
2006-12-14 |
Novartis Ag |
Organic compounds
|
|
ES2348099T3
(es)
|
2005-06-10 |
2010-11-30 |
Merck Patent Gmbh |
Oxindoles como inhibidores de cinasa.
|
|
WO2006138418A2
(en)
|
2005-06-14 |
2006-12-28 |
President And Fellows Of Harvard College |
Improvement of cognitive performance with sirtuin activators
|
|
EP1896033A4
(en)
|
2005-06-15 |
2010-12-22 |
New York Blood Ct Inc |
ANTIVIRAL COMPOSITIONS WITH HETEROCYCLIC SUBSTITUTED PHENYLFURANES AND RELATED COMPOUNDS
|
|
AU2006269459B2
(en)
|
2005-07-07 |
2013-02-07 |
Sirtris Pharmaceuticals, Inc. |
Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
|
|
TW200740755A
(en)
|
2005-07-13 |
2007-11-01 |
Bayer Cropscience Sa |
Dihalogenation of N,O-disubstituted hydroxypyridones and their uses
|
|
JP2007063268A
(ja)
|
2005-08-05 |
2007-03-15 |
Tanabe Seiyaku Co Ltd |
医薬組成物
|
|
JP2007056213A
(ja)
|
2005-08-26 |
2007-03-08 |
Fujifilm Corp |
焼結含油軸受油用組成物、並びにそれを用いた軸受け装置及び摺動部材
|
|
TW200745034A
(en)
|
2005-09-01 |
2007-12-16 |
Astellas Pharma Inc |
New compounds
|
|
NZ591443A
(en)
*
|
2005-09-22 |
2013-04-26 |
Intermune Inc |
Granule formation of pirfenidone and pharmaceutically acceptable excipients
|
|
WO2007037543A1
(ja)
|
2005-09-29 |
2007-04-05 |
Banyu Pharmaceutical Co., Ltd. |
ビアリールアミド誘導体
|
|
WO2007040208A1
(ja)
*
|
2005-10-03 |
2007-04-12 |
Ono Pharmaceutical Co., Ltd. |
含窒素複素環化合物およびその医薬用途
|
|
WO2007044796A2
(en)
|
2005-10-11 |
2007-04-19 |
Nps Pharmaceuticals, Inc. |
Pyridazinone compounds as calcilytics
|
|
CA2626789A1
(en)
|
2005-10-21 |
2007-04-26 |
Exelixis, Inc. |
Pyrimidinones as casein kinase ii (ck2) modulators
|
|
JP2007145819A
(ja)
|
2005-10-28 |
2007-06-14 |
Tanabe Seiyaku Co Ltd |
医薬組成物
|
|
WO2007053610A2
(en)
|
2005-11-01 |
2007-05-10 |
The Regents Of The University Of California |
Methods of treating atrial fibrillation wtih pirfenidone
|
|
US7622466B2
(en)
|
2005-11-18 |
2009-11-24 |
Hoffman-La Roche Inc. |
Azaindole-2-carboxamide derivatives
|
|
AR057986A1
(es)
|
2005-11-21 |
2008-01-09 |
Japan Tobacco Inc |
Compuesto heterociclico y su uso farmaceutico
|
|
US20110034495A1
(en)
*
|
2005-11-23 |
2011-02-10 |
Intermune, Inc. |
Method of Modulating Stress-Activated Protein Kinase System
|
|
US7728017B2
(en)
|
2005-11-30 |
2010-06-01 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of c-Met and uses thereof
|
|
US20090088574A1
(en)
*
|
2005-12-21 |
2009-04-02 |
Eisai R&D Management Co., Ltd. |
Crystal of 1,2-dihydropyridine compound (type iv)
|
|
CA2634056C
(en)
|
2005-12-21 |
2014-06-10 |
Eisai R&D Management Co., Ltd. |
Amorphous form of 1,2-dihydropyridine compound
|
|
WO2007076104A1
(en)
*
|
2005-12-23 |
2007-07-05 |
Amgen Inc. |
Vanilloid receptor ligands and their use in treatments
|
|
UY30117A1
(es)
|
2006-01-31 |
2007-06-29 |
Tanabe Seiyaku Co |
Compuesto amina trisustituido
|
|
US8076487B2
(en)
|
2006-02-02 |
2011-12-13 |
Kumiai Chemical Industry Co., Ltd. |
Pyridone derivative and herbicide
|
|
TW200803855A
(en)
|
2006-02-24 |
2008-01-16 |
Kalypsys Inc |
Quinolones useful as inducible nitric oxide synthase inhibitors
|
|
US7728031B2
(en)
|
2006-02-24 |
2010-06-01 |
Abbott Laboratories |
Octahydro-pyrrolo[3,4-b]pyrrole derivatives
|
|
EP2001875A2
(en)
|
2006-03-08 |
2008-12-17 |
Takeda San Diego, Inc. |
Glucokinase activators
|
|
WO2007108968A2
(en)
|
2006-03-13 |
2007-09-27 |
Merck & Co., Inc. |
Ophthalmic compositions for treating ocular hypertension
|
|
CN100396669C
(zh)
|
2006-03-15 |
2008-06-25 |
浙江省医学科学院 |
一种抗纤维化药物吡非尼酮的制备方法
|
|
AU2007228784B2
(en)
|
2006-03-22 |
2012-03-08 |
Janssen Pharmaceutica N.V. |
Cyclic-alkylaminederivatives as inhibitors of the interaction between MDM2 and p53
|
|
EP2010488A2
(en)
|
2006-04-05 |
2009-01-07 |
Vitae Pharmaceuticals, Inc. |
Renin inhibitors
|
|
US20090275581A1
(en)
|
2006-04-05 |
2009-11-05 |
Baldwin John J |
Renin inhibitors
|
|
US20100055116A1
(en)
|
2006-04-13 |
2010-03-04 |
Liou Hsiou-Chi |
Methods and Compositions for Targeting c-Rel
|
|
CA2650711A1
(en)
|
2006-04-28 |
2007-11-08 |
Northwestern University |
Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
|
|
WO2007127475A2
(en)
|
2006-04-28 |
2007-11-08 |
Northwestern University |
Pyridazines for demyelinating diseases and neuropathic pain
|
|
HUE033281T2
(en)
|
2006-05-04 |
2017-11-28 |
Chroma Therapeutics Ltd |
p38 mitogen-activated protein (MAP) kinase inhibitors
|
|
EP2016072B1
(en)
|
2006-05-05 |
2014-07-16 |
Millennium Pharmaceuticals, Inc. |
Factor xa inhibitors
|
|
WO2007139150A1
(ja)
|
2006-05-30 |
2007-12-06 |
The University Of Tokushima |
TNFα阻害物質を含有してなる抗インフルエンザウイルス剤
|
|
EP2035005A4
(en)
|
2006-06-09 |
2011-07-06 |
Kemia Inc |
THERAPY BASED ON CYTOKINE INHIBITORS
|
|
CN101484167B
(zh)
|
2006-06-15 |
2012-07-04 |
上海睿星基因技术有限公司 |
吡啶酮类衍生物预防和治疗放射性肺损伤的用途
|
|
GB0724349D0
(en)
|
2007-12-13 |
2008-01-30 |
Prolysis Ltd |
Antibacterial agents
|
|
GB0612428D0
(en)
|
2006-06-22 |
2006-08-02 |
Prolysis Ltd |
Antibacterial agents
|
|
CA2656067C
(en)
|
2006-06-23 |
2014-08-12 |
Radius Health, Inc. |
Treatment of vasomotor symptoms with selective estrogen receptor modulators
|
|
CA2657034A1
(en)
*
|
2006-07-19 |
2008-01-24 |
University Of Georgia Research Foundation, Inc. |
Pyridinone diketo acids: inhibitors of hiv replication in combination therapy
|
|
EP2079724B1
(en)
|
2006-07-20 |
2010-05-26 |
Amgen Inc. |
Substituted pyridone compounds and methods of use
|
|
EP2502918B1
(en)
|
2006-07-25 |
2015-03-25 |
Cephalon, Inc. |
Pyridazinone Derivatives
|
|
JP4747985B2
(ja)
|
2006-08-02 |
2011-08-17 |
コニカミノルタオプト株式会社 |
光学フィルム、それを用いた偏光板及び液晶表示装置
|
|
MX2009001155A
(es)
|
2006-08-02 |
2009-02-10 |
Lg Life Sciences Ltd |
Inhibidores de caspasa basados en la estructura de piridazinona.
|
|
JP5073746B2
(ja)
|
2006-08-25 |
2012-11-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Mch拮抗作用を有する新規ピリドン誘導体及びこの化合物を含む薬物
|
|
CN100516126C
(zh)
|
2006-09-06 |
2009-07-22 |
北京理工大学 |
一种离子液体
|
|
AR063706A1
(es)
*
|
2006-09-11 |
2009-02-11 |
Cgi Pharmaceuticals Inc |
Determinadas amidas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmaceuticas que las comprenden.
|
|
JP2008076948A
(ja)
|
2006-09-25 |
2008-04-03 |
Konica Minolta Medical & Graphic Inc |
感光性平版印刷版材料
|
|
KR101390076B1
(ko)
|
2006-11-08 |
2014-04-29 |
브리스톨-마이어스 스큅 컴퍼니 |
피리디논 화합물
|
|
KR20080045538A
(ko)
|
2006-11-20 |
2008-05-23 |
에스케이케미칼주식회사 |
피리딘 화합물을 포함하는 염증 및 면역질환 치료용 약제조성물
|
|
CN1962642A
(zh)
|
2006-11-21 |
2007-05-16 |
南开大学 |
具有除草活性的三氟甲基苯基哒嗪类衍生物及制备方法
|
|
GB0624105D0
(en)
|
2006-12-01 |
2007-01-10 |
Sterix Ltd |
Use
|
|
ES2483866T3
(es)
|
2006-12-05 |
2014-08-08 |
Janssen Pharmaceutica Nv |
Derivados de diaza-espiro-piridinona sustituidos novedosos para uso en enfermedades mediadas por MCH-1
|
|
WO2008076562A1
(en)
|
2006-12-14 |
2008-06-26 |
Eli Lilly And Company |
5- [4- (azetidin-3-yl0xy) -phenyl] -2-phenyl-5h-thiaz0l0 [5,4-c] pyridin-4-0ne derivatives and their use as mch receptor antagonists
|
|
EP2094662B1
(en)
|
2006-12-14 |
2012-04-11 |
Astellas Pharma Inc. |
Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents
|
|
JP5419706B2
(ja)
|
2006-12-20 |
2014-02-19 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼアクチベーター
|
|
US20100210649A1
(en)
|
2006-12-21 |
2010-08-19 |
Sloan-Kettering Institute For Cancer Research |
Pyridazinones and furan-containing compounds
|
|
US7795249B2
(en)
|
2006-12-22 |
2010-09-14 |
Millennium Pharmaceuticals, Inc. |
Certain pyrazoline derivatives with kinase inhibitory activity
|
|
JP5421783B2
(ja)
|
2006-12-27 |
2014-02-19 |
サノフイ |
Rhoキナーゼ阻害剤としての置換イソキノロン及びイソキノリノン誘導体
|
|
US9623021B2
(en)
|
2007-01-22 |
2017-04-18 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
KR101638035B1
(ko)
|
2007-01-22 |
2016-07-11 |
지티엑스, 인코포레이티드 |
핵 수용체에 결합하는 물질
|
|
CN101235030A
(zh)
|
2007-01-30 |
2008-08-06 |
中南大学 |
1-取代-5-三氟甲基-2-(1h)吡啶酮化合物、制备方法及其用途
|
|
CA2676173A1
(en)
|
2007-02-16 |
2008-08-28 |
Amgen Inc. |
Nitrogen-containing heterocyclyl ketones and their use as c-met inhibitors
|
|
DE102007007751A1
(de)
|
2007-02-16 |
2008-08-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2008106202A1
(en)
|
2007-02-27 |
2008-09-04 |
Housey Gerard M |
Theramutein modulators
|
|
JP5134834B2
(ja)
|
2007-03-01 |
2013-01-30 |
東ソー株式会社 |
5,5−二置換−3−ピロリン−2−オン誘導体の製造方法
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
GB0722769D0
(en)
|
2007-11-21 |
2008-01-02 |
Biolipox Ab |
New compounds
|
|
EP2073799A4
(en)
|
2007-03-12 |
2009-08-19 |
Vm Discovery Inc |
NOVEL ACTIVE SUBSTANCES FROM CALCIUMIONAL CHANNEL MODULATORS
|
|
JP5147866B2
(ja)
|
2007-03-15 |
2013-02-20 |
メルク・シャープ・アンド・ドーム・コーポレーション |
グルカン合成酵素阻害剤として有用であるピリダジノン誘導体
|
|
US20080234332A1
(en)
|
2007-03-20 |
2008-09-25 |
Xiong Cai |
Raf kinase inhibitors containing a zinc binding moiety
|
|
EP2171478A4
(en)
|
2007-03-30 |
2013-01-30 |
Univ California |
IN VIVO IMAGING METHOD FOR SULPHOTRANSFERASES
|
|
EP2142498A2
(en)
|
2007-04-02 |
2010-01-13 |
Institute for Oneworld Health |
Cftr inhibitor compounds and uses thereof
|
|
UA101611C2
(ru)
|
2007-04-03 |
2013-04-25 |
Аррей Байофарма Инк. |
СОЕДИНЕНИЯ ИМИДАЗО[1,2-а]ПИРИДИНА КАК ИНГИБИТОРЫ ТИРОЗИНКИНАЗЫ РЕЦЕПТОРОВ
|
|
WO2008124575A1
(en)
|
2007-04-05 |
2008-10-16 |
Smithkline Beecham Corporation |
Renin inhibitors
|
|
WO2008124582A1
(en)
|
2007-04-05 |
2008-10-16 |
Smithkline Beecham Corporation |
Renin inhibitors
|
|
US20100129933A1
(en)
|
2007-04-26 |
2010-05-27 |
Forschungszentrum Karlsruhe Gmbh |
Method for detecting the binding between mdm2 and the proteasome
|
|
TW200904421A
(en)
|
2007-05-03 |
2009-02-01 |
Astellas Pharma Inc |
New compounds
|
|
EP2164840A2
(en)
|
2007-05-09 |
2010-03-24 |
Vertex Pharmaceuticals Incorporated |
Modulators of cftr
|
|
WO2008144720A2
(en)
|
2007-05-21 |
2008-11-27 |
University Of Washington |
Inhibitors of igf-1r signaling for the treatment of respiratory disorders
|
|
MX2007006349A
(es)
|
2007-05-29 |
2009-02-18 |
Cell Therapy And Technology S |
Nuevo proceso de sintesis para la obtencion de 5-metil-1-fenil-2-(ih)-piridona, composicion y uso de la misma.
|
|
WO2008147169A2
(es)
|
2007-05-29 |
2008-12-04 |
Cell Therapy Technology, S.A. De C.V. |
Microemolsion conteniendo pirfenidona
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
DE102007028406A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
AU2008265595B2
(en)
|
2007-06-20 |
2014-12-04 |
PureTech LYT 100 Inc. |
Substituted N-Aryl pyridinones as fibrotic inhibitors
|
|
US20100168174A1
(en)
|
2007-07-13 |
2010-07-01 |
Eisai R&D Management Co., Ltd. |
Combination of AMPA Receptor Antagonists and Acetylcholinesterase Inhibitors for the Treatment of Neuropathic Pain
|
|
US20100179193A1
(en)
|
2007-07-13 |
2010-07-15 |
Eisai R&D Management Co., Ltd |
AMPA Receptor Antagonists and Zonisamide for Neuropathic Pain
|
|
WO2009011410A1
(en)
|
2007-07-13 |
2009-01-22 |
Eisai R & D Management Co., Ltd. |
Ampa receptor antagonists and aldose reductase inhibitors for neuropathic pain
|
|
PL2170864T3
(pl)
|
2007-07-17 |
2012-02-29 |
Bristol Myers Squibb Co |
Agoniści receptora gpr119 sprężonego z białkiem g - pirydon
|
|
DE102007035333A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
EP2174547B1
(en)
*
|
2007-08-10 |
2017-01-18 |
Kumiai Chemical Industry CO., LTD. |
Pest control agent composition and pest controlling method
|
|
MX2007009796A
(es)
|
2007-08-14 |
2009-02-25 |
Cell Therapy And Technology S |
Gel conteniendo pirfenidona.
|
|
CN101371833A
(zh)
|
2007-08-23 |
2009-02-25 |
中南大学 |
1-芳基-2(1h)-吡啶酮类化合物在制备治疗皮肤瘙痒药物中的应用
|
|
WO2009029625A1
(en)
|
2007-08-27 |
2009-03-05 |
Kalypsys, Inc. |
4- [heterocyclyl-methyl] -8-fluoro-quinolin-2-ones useful as nitric oxide synthase inhibitors
|
|
US20090131485A1
(en)
|
2007-09-10 |
2009-05-21 |
Concert Pharmaceuticals, Inc. |
Deuterated pirfenidone
|
|
BRPI0816970A2
(pt)
|
2007-09-14 |
2015-03-24 |
Ortho Mcneil Janssen Pharm |
1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
|
|
WO2009039773A1
(fr)
|
2007-09-19 |
2009-04-02 |
Central South University |
Nouvelle utilisation thérapeutique d'une aryl-2(1h)-pyridone substituée en position 1
|
|
WO2009054544A1
(en)
|
2007-10-26 |
2009-04-30 |
Eisai R & D Management Co., Ltd. |
Ampa receptor antagonists for parkinson's disease and movement disorders
|
|
WO2009054543A1
(en)
|
2007-10-26 |
2009-04-30 |
Eisai R & D Management Co., Ltd. |
Ampa receptor antagonists and zonisamide for parkinson's disease and movement disorders
|
|
JP5423679B2
(ja)
|
2007-10-31 |
2014-02-19 |
日産化学工業株式会社 |
ピリダジノン化合物及びp2x7受容体阻害剤
|
|
JP5479105B2
(ja)
|
2007-11-05 |
2014-04-23 |
国立大学法人佐賀大学 |
新規ユビキリン結合性小分子
|
|
EP2225237A2
(de)
|
2007-11-22 |
2010-09-08 |
Boehringer Ingelheim International GmbH |
Organische verbindungen
|
|
WO2009073620A2
(en)
|
2007-11-30 |
2009-06-11 |
Newlink Genetics |
Ido inhibitors
|
|
CA2708780A1
(en)
|
2007-12-11 |
2009-06-18 |
Research Development Foundation |
Small molecules for neuronal differentiation of embryonic stem cells
|
|
EP2254577A1
(en)
|
2007-12-26 |
2010-12-01 |
Eisai R&D Management Co., Ltd. |
Ampa receptor antagonists for epilepsy, mental disorders or deficits in sensory organ
|
|
EP2222296A2
(en)
|
2007-12-26 |
2010-09-01 |
Eisai R&D Management Co., Ltd. |
Ampa receptor antagonists and zonisamide for epilepsy
|
|
ES2531396T3
(es)
|
2008-01-23 |
2015-03-13 |
Bristol Myers Squibb Co |
Proceso para preparar compuestos de piridinona
|
|
ES2370378T3
(es)
|
2008-01-30 |
2011-12-14 |
Cephalon, Inc. |
Derivados sustituidos de piperidina espirocíclica como ligandos del receptor de histamina h3.
|
|
CN101951776A
(zh)
|
2008-02-25 |
2011-01-19 |
默沙东公司 |
四氢-1h-吡咯稠合吡啶酮
|
|
WO2009111785A2
(en)
|
2008-03-07 |
2009-09-11 |
Solanan, Inc. |
Treatment of sepsis with 5-ethyl-1-phenyl-2(1h)-pyridone and novel methods for synthesis
|
|
US8349864B2
(en)
|
2008-03-25 |
2013-01-08 |
New Mexico Technical Research Foundation |
Pyrano [3,2-C] pyridones and related heterocyclic compounds as pharmaceutical agents for treating disorders responsive to apoptosis, antiproliferation or vascular disruption, and the use thereof
|
|
WO2009146034A2
(en)
|
2008-03-31 |
2009-12-03 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors and methods of use thereof
|
|
WO2009124119A2
(en)
|
2008-04-01 |
2009-10-08 |
The Trustes of Columbia University in the City of New York |
Phosphodiesterase inhibitors and uses thereof
|
|
WO2009124553A2
(en)
|
2008-04-09 |
2009-10-15 |
Neurokey A/S |
Use of hypothermia inducing drugs
|
|
US8889714B2
(en)
|
2008-05-05 |
2014-11-18 |
Actelion Pharmaceuticals Ltd. |
3,4-substituted piperidine derivatives as renin inhibitors
|
|
EP2328586A2
(en)
|
2008-05-20 |
2011-06-08 |
Cephalon, Inc. |
Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands
|
|
EP2296653B1
(en)
|
2008-06-03 |
2016-01-27 |
Intermune, Inc. |
Compounds and methods for treating inflammatory and fibrotic disorders
|
|
CN102131801B
(zh)
|
2008-06-25 |
2015-04-08 |
福拉姆医药股份有限公司 |
1,2-二取代的杂环化合物
|
|
WO2009156484A2
(en)
|
2008-06-27 |
2009-12-30 |
Novartis Ag |
Organic compounds
|
|
ES2429129T3
(es)
|
2008-07-11 |
2013-11-13 |
Irm Llc |
4-Fenoximetilpiperidinas como moduladores de la actividad de GPR119
|
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
|
EP2318388A2
(en)
|
2008-07-23 |
2011-05-11 |
Schering Corporation |
Tricyclic spirocycle derivatives and methods of use thereof
|
|
MX2011001872A
(es)
|
2008-08-18 |
2011-05-23 |
Univ Yale |
Moduladores de mif.
|
|
WO2010025087A1
(en)
|
2008-08-25 |
2010-03-04 |
Smithkline Beecham Corporation |
Prolyl hydroxylase inhibitors
|
|
WO2010029299A1
(en)
|
2008-09-12 |
2010-03-18 |
Biolipox Ab |
Pyrimidinone derivaties for use as medicaments
|
|
WO2010044885A2
(en)
|
2008-10-17 |
2010-04-22 |
Whitehead Institute For Biomedical Research |
Soluble mtor complexes and modulators thereof
|
|
US8703962B2
(en)
*
|
2008-10-24 |
2014-04-22 |
Purdue Pharma L.P. |
Monocyclic compounds and their use as TRPV1 ligands
|
|
US20110288134A1
(en)
|
2008-10-29 |
2011-11-24 |
Pacific Therapeutics Ltd. |
Composition and method for treating fibrosis
|
|
US7635707B1
(en)
*
|
2008-11-10 |
2009-12-22 |
Intermune, Inc. |
Pirfenidone treatment for patients with atypical liver function
|
|
US20110313004A1
(en)
|
2008-12-04 |
2011-12-22 |
Concert Pharmaceuticals, Inc. |
Deuterated pyridinones
|
|
RU2016116516A
(ru)
|
2008-12-08 |
2018-12-07 |
Мандифарма Интернэшнл Корпорейшн Лимитед |
Композиции ингибиторов тирозинкиназных рецепторов белков
|
|
AU2009326797B2
(en)
|
2008-12-10 |
2012-12-13 |
Merck Canada Inc. |
3,4 - substituted piperidine derivatives as renin inhibitors
|
|
SG171308A1
(en)
|
2008-12-11 |
2011-07-28 |
Shionogi & Co |
Synthesis of carbamoylpyridone hiv integrase inhibitors and intermediates
|
|
WO2010075561A1
(en)
|
2008-12-23 |
2010-07-01 |
President And Fellows Of Harvard College |
Small molecule inhibitors of necroptosis
|
|
JP5632857B2
(ja)
|
2009-01-07 |
2014-11-26 |
ヘンケル コーポレイションHenkel Corporation |
過酸化水素錯体および嫌気性接着剤の硬化システムにおけるそれらの使用
|
|
EP2389227A4
(en)
|
2009-01-26 |
2012-08-08 |
Intermune Inc |
METHOD FOR THE TREATMENT OF ACUTE MYOCARDINE CARDS AND ASSOCIATED ILLNESSES THEREOF
|
|
WO2010088177A1
(en)
|
2009-02-02 |
2010-08-05 |
Merck Sharp & Dohme Corp. |
Inhibitors of akt activity
|
|
BRPI1008498B8
(pt)
*
|
2009-02-05 |
2021-05-25 |
Takeda Pharmaceuticals Co |
compostos de piridazinona úteis como inibidores da fosfodiesterase 10a, composição farmacêutica, e, uso de um composto
|
|
US8563583B2
(en)
|
2009-03-09 |
2013-10-22 |
Bristol-Myers Squibb Company |
Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
|
EP2406233B1
(en)
|
2009-03-09 |
2013-11-13 |
Bristol-Myers Squibb Company |
Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
|
WO2010107816A2
(en)
|
2009-03-16 |
2010-09-23 |
Promega Corporation |
Nucleic acid binding dyes and uses therefor
|
|
US8673919B2
(en)
|
2009-03-27 |
2014-03-18 |
Ardea Biosciences, Inc. |
Dihydropyridin sulfonamides and dihydropyridin sulfamides as MEK inhibitors
|
|
RU2549697C2
(ru)
|
2009-04-20 |
2015-04-27 |
Марроун Био Инновэйшнс, Инк. |
Композиция и способ для контроля численности моллюсков
|
|
SG10201401836RA
(en)
|
2009-04-27 |
2014-10-30 |
Elan Pharm Inc |
Pyridinone antagonists of alpha-4 integrins
|
|
JP2012131708A
(ja)
|
2009-04-28 |
2012-07-12 |
Nissan Chem Ind Ltd |
4位置換ピリダジノン化合物及びp2x7受容体阻害剤
|
|
SG175877A1
(en)
|
2009-05-04 |
2011-12-29 |
Plexxikon Inc |
Compounds and methods for inhibition of renin, and indications therefor
|
|
WO2010132864A1
(en)
*
|
2009-05-15 |
2010-11-18 |
Intermune, Inc. |
Methods of treating hiv patients with anti-fibrotics
|
|
WO2010135470A1
(en)
|
2009-05-19 |
2010-11-25 |
Intermune, Inc. |
Pifenidone derivatives for treating bronchial asthma
|
|
EP2474533B1
(en)
|
2009-05-25 |
2015-02-25 |
Central South University |
Preparation of 1-(substituted benzyl)-5-trifluoromethyl-2-(1h)pyridone compounds and salts thereof and their applications
|
|
US20100305326A1
(en)
|
2009-06-02 |
2010-12-02 |
Marquette University |
Chemical Fragment Screening and Assembly Utilizing Common Chemistry for NMR Probe Introduction and Fragment Linkage
|
|
TWI434833B
(zh)
*
|
2009-06-03 |
2014-04-21 |
Intermune Inc |
用於合成吡非尼酮(pirfenidone)的改良方法
|
|
JP2012528871A
(ja)
|
2009-06-03 |
2012-11-15 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
メラニン凝集ホルモン受容体1アンタゴニストとしてのビス−ピリジルピリドン類
|
|
EP2437598A4
(en)
|
2009-06-03 |
2012-10-31 |
Glaxosmithkline Llc |
BIS-PYRIDYLPYRIDONES AS MELANGE-CONCENTRATION HORMONE RECEPTOR ANTAGONISTS
|
|
WO2010141539A1
(en)
|
2009-06-03 |
2010-12-09 |
Glaxosmithkline Llc |
Bis-pyridylpyridones as melanin-concentrating hormone receptor 1 antagonists
|
|
JP2012528872A
(ja)
|
2009-06-03 |
2012-11-15 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
メラニン凝集ホルモン受容体1アンタゴニストとしてのビス−ピリジルピリドン類
|
|
AR092742A1
(es)
|
2012-10-02 |
2015-04-29 |
Intermune Inc |
Piridinonas antifibroticas
|