AU2001249397A1 - Oxindole inhibitors of factor xa - Google Patents

Oxindole inhibitors of factor xa

Info

Publication number
AU2001249397A1
AU2001249397A1 AU2001249397A AU4939701A AU2001249397A1 AU 2001249397 A1 AU2001249397 A1 AU 2001249397A1 AU 2001249397 A AU2001249397 A AU 2001249397A AU 4939701 A AU4939701 A AU 4939701A AU 2001249397 A1 AU2001249397 A1 AU 2001249397A1
Authority
AU
Australia
Prior art keywords
factor
oxindole
inhibitors
oxindole inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001249397A
Inventor
Kim A. Kane-Maguire
Charles K. Marlowe
Robert M. Scarborough Jr.
Bing-Yan Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COR Therapeutics Inc
Original Assignee
COR Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by COR Therapeutics Inc filed Critical COR Therapeutics Inc
Publication of AU2001249397A1 publication Critical patent/AU2001249397A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
AU2001249397A 2000-03-24 2001-03-26 Oxindole inhibitors of factor xa Abandoned AU2001249397A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19172000P 2000-03-24 2000-03-24
US60191720 2000-03-24
PCT/US2001/009374 WO2001072708A2 (en) 2000-03-24 2001-03-26 OXINDOLE INHIBITORS OF FACTOR Xa

Publications (1)

Publication Number Publication Date
AU2001249397A1 true AU2001249397A1 (en) 2001-10-08

Family

ID=22706669

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001249397A Abandoned AU2001249397A1 (en) 2000-03-24 2001-03-26 Oxindole inhibitors of factor xa

Country Status (4)

Country Link
US (1) US6548517B2 (en)
EP (1) EP1272483A2 (en)
AU (1) AU2001249397A1 (en)
WO (1) WO2001072708A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
CN1688586B (en) * 2002-08-14 2012-05-09 泰博特克药品有限公司 Broadspectrum substituted oxindole sulfonamide HIV protease inhibitors
JP4744149B2 (en) 2002-12-03 2011-08-10 ファーマサイクリックス インコーポレイテッド 2- (2-Hydroxybiphenyl-3-yl) -1H-benzimidazole-5-carboxamidine derivatives as factor VIIA inhibitors
WO2005044978A2 (en) * 2003-07-15 2005-05-19 Washington University Methods of treating, preventing and inhibiting cancer metastasis and tumor formation
US7414052B2 (en) 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en) 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
CA2608116A1 (en) 2005-05-10 2006-11-16 Intermune, Inc. Method of modulating stress-activated protein kinase system
RU2415138C2 (en) 2005-07-13 2011-03-27 Ф. Хоффманн-Ля Рош Аг Benzimidazole and indole derivatives as selective 5-ht6 and/or 5-ht2a receptor antagonists
TWI387592B (en) 2005-08-30 2013-03-01 Novartis Ag Substituted benzimidazoles and methods of their use as inhibitors of kinases associated with tumorigenesis
DE102008022221A1 (en) * 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitors of human aldosterone synthase CYP11B2
EP2296653B1 (en) 2008-06-03 2016-01-27 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
AR092742A1 (en) 2012-10-02 2015-04-29 Intermune Inc ANTIFIBROTIC PYRIDINONES
CA2943363A1 (en) 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones
AU2016233568A1 (en) 2015-03-13 2017-10-05 Forma Therapeutics, Inc. Alpha-cinnamide compounds and compositions as HDAC8 inhibitors
HUE050083T2 (en) 2015-11-06 2020-11-30 Hoffmann La Roche Indolin-2-one derivatives
CA3181537A1 (en) 2020-05-06 2021-11-11 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
KR20230104781A (en) 2020-10-05 2023-07-10 인라이븐 테라퓨틱스, 인크. 5- and 6-azaindole compounds for inhibition of BCR-ABL tyrosine kinase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4345081A (en) * 1980-02-15 1982-08-17 American Hoechst Corporation Spiro[indoline-3,4'-piperidine]s
PT798295E (en) * 1994-12-02 2003-07-31 Yamanouchi Pharma Co Ltd NEW AMIDINONEFTILO DERIVATIVES OR SALT OF THIS
US5750528A (en) * 1995-02-01 1998-05-12 The Dupont Merck Pharmaceutical Company Blockade of neuronal m-channels as a therapeutic approach to the treatment of neurological disease
JP2002508771A (en) * 1997-06-26 2002-03-19 イーライ・リリー・アンド・カンパニー Antithrombotic agent
SI1042287T1 (en) 1997-12-24 2005-10-31 Aventis Pharma Deutschland Gmbh Indole derivatives as inhibitors of factor xa
AU2074699A (en) 1998-01-26 1999-08-09 Yamanouchi Pharmaceutical Co., Ltd. Novel benzene-fused heterocyclic derivatives or salts thereof
TR200101860T2 (en) * 1998-12-17 2001-12-21 F.Hoffmann-La Roche Ag 4-alkenyl (and alkynyl) oxidols as cyclin-dependent kinase inhibitors

Also Published As

Publication number Publication date
WO2001072708A2 (en) 2001-10-04
US6548517B2 (en) 2003-04-15
US20020052368A1 (en) 2002-05-02
WO2001072708A3 (en) 2002-05-23
EP1272483A2 (en) 2003-01-08

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