EA028821B9 - Соединения и способы для модуляции киназ, а также показания к их применению - Google Patents

Соединения и способы для модуляции киназ, а также показания к их применению

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Publication number
EA028821B9
EA028821B9 EA201391019A EA201391019A EA028821B9 EA 028821 B9 EA028821 B9 EA 028821B9 EA 201391019 A EA201391019 A EA 201391019A EA 201391019 A EA201391019 A EA 201391019A EA 028821 B9 EA028821 B9 EA 028821B9
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
methods
kinase modulation
indications therefor
indications
Prior art date
Application number
EA201391019A
Other languages
English (en)
Other versions
EA201391019A1 (ru
EA028821B1 (ru
Inventor
Прабха Н. Ибрахим
Чао Чжан
Вэйн Спевак
Цзячжун Чжан
Гуосян Ву
Джек Лин
Ханна Чо
Марика Нэспи
Сонюань Ши
Тодд Эвинг
Ин Чжан
Original Assignee
Плексксикон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46638904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA028821(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Плексксикон, Инк. filed Critical Плексксикон, Инк.
Publication of EA201391019A1 publication Critical patent/EA201391019A1/ru
Publication of EA028821B1 publication Critical patent/EA028821B1/ru
Publication of EA028821B9 publication Critical patent/EA028821B9/ru

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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Abstract

Описаны соединения формулы (lg-1)или фармацевтически приемлемая соль или стереоизомер указанного соединения, активные в отношении протеинкиназ, а также способы получения и применения указанных соединений для лечения заболеваний и состояний, связанных с аберрантной активностью протеинкиназ.
EA201391019A 2011-02-07 2012-02-01 Соединения и способы для модуляции киназ, а также показания к их применению EA028821B9 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161440339P 2011-02-07 2011-02-07
PCT/US2012/023543 WO2012109075A1 (en) 2011-02-07 2012-02-01 Compounds and methods for kinase modulation, and indications therefor

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EA201391019A1 EA201391019A1 (ru) 2014-01-30
EA028821B1 EA028821B1 (ru) 2018-01-31
EA028821B9 true EA028821B9 (ru) 2018-10-31

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Families Citing this family (87)

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Publication number Priority date Publication date Assignee Title
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