DK2672967T3 - Forbindelser og fremgangsmåder til kinasemodulering og indikationer derfor - Google Patents

Forbindelser og fremgangsmåder til kinasemodulering og indikationer derfor Download PDF

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Publication number
DK2672967T3
DK2672967T3 DK12745360.3T DK12745360T DK2672967T3 DK 2672967 T3 DK2672967 T3 DK 2672967T3 DK 12745360 T DK12745360 T DK 12745360T DK 2672967 T3 DK2672967 T3 DK 2672967T3
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indications
relationships
modulation
chinese
methods
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DK12745360.3T
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Prabha N Ibrahim
Chao Zhang
Wayne Spevak
Jiazhong Zhang
Guoxian Wu
Jack Lin
Hanna Cho
Marika Nespi
Songyuan Shi
Todd Ewing
Ying Zhang
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Plexxikon Inc
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
DK12745360.3T 2011-02-07 2012-02-01 Forbindelser og fremgangsmåder til kinasemodulering og indikationer derfor DK2672967T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161440339P 2011-02-07 2011-02-07
PCT/US2012/023543 WO2012109075A1 (en) 2011-02-07 2012-02-01 Compounds and methods for kinase modulation, and indications therefor

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DK2672967T3 true DK2672967T3 (da) 2019-01-02

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US (3) US9624213B2 (da)
EP (1) EP2672967B1 (da)
JP (3) JP5941069B2 (da)
KR (1) KR101911972B1 (da)
CN (1) CN103517710B (da)
AR (1) AR085316A1 (da)
AU (1) AU2012214762B2 (da)
CA (1) CA2826123C (da)
CL (1) CL2013002228A1 (da)
CO (1) CO6781514A2 (da)
CR (1) CR20130374A (da)
CY (1) CY1121511T1 (da)
DK (1) DK2672967T3 (da)
EA (1) EA028821B9 (da)
EC (1) ECSP13012869A (da)
ES (1) ES2696023T3 (da)
HR (1) HRP20181779T1 (da)
HU (1) HUE040136T2 (da)
IL (1) IL227698B (da)
LT (1) LT2672967T (da)
MA (1) MA34948B1 (da)
MX (1) MX358128B (da)
MY (1) MY162950A (da)
PE (1) PE20141360A1 (da)
PL (1) PL2672967T3 (da)
PT (1) PT2672967T (da)
RS (1) RS58455B1 (da)
SG (1) SG192686A1 (da)
SI (1) SI2672967T1 (da)
TR (1) TR201816421T4 (da)
TW (1) TWI640521B (da)
UY (1) UY33899A (da)
WO (1) WO2012109075A1 (da)
ZA (1) ZA201305856B (da)

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SG183036A1 (en) 2007-07-17 2012-08-30 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
WO2009143018A2 (en) 2008-05-19 2009-11-26 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
MX349923B (es) 2009-04-03 2017-08-21 Hoffmann La Roche Composiciones del ácido propano-1-sulfónico {3-[5-(4-cloro-fenil)- 1h-pirrolo [2,3-b]-piridina-3-carbonil]-2,4-difluoro-fenil]-amida y el uso de las mismas.
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
ES2633317T3 (es) 2009-11-06 2017-09-20 Plexxikon, Inc. Compuestos y métodos para la modulación de quinasas, e indicaciones para ello
BR112012011792A2 (pt) 2009-11-18 2015-10-13 Plexxikon Inc "compostos e métodos para modulação de quinases, e indicações para os mesmos"
RU2012131373A (ru) 2009-12-23 2014-01-27 Плексксикон, Инк. Соединения и способы модулирования киназы, а также показания для такого модулирования
TWI619713B (zh) 2010-04-21 2018-04-01 普雷辛肯公司 用於激酶調節的化合物和方法及其適應症
MY162950A (en) * 2011-02-07 2017-07-31 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
RU2631487C2 (ru) 2011-05-17 2017-09-22 Плексксикон Инк. Модуляция киназ и показания к её применению
JP2015502958A (ja) * 2011-12-09 2015-01-29 オンコメッド ファーマシューティカルズ インコーポレイテッド がんの処置のための併用療法
US9358235B2 (en) 2012-03-19 2016-06-07 Plexxikon Inc. Kinase modulation, and indications therefor
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