IT1303759B1 - Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico. - Google Patents

Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.

Info

Publication number
IT1303759B1
IT1303759B1 IT1998MI002480A ITMI982480A IT1303759B1 IT 1303759 B1 IT1303759 B1 IT 1303759B1 IT 1998MI002480 A IT1998MI002480 A IT 1998MI002480A IT MI982480 A ITMI982480 A IT MI982480A IT 1303759 B1 IT1303759 B1 IT 1303759B1
Authority
IT
Italy
Prior art keywords
azaindolyl
preparation
carboxylic acid
improved procedure
procedure
Prior art date
Application number
IT1998MI002480A
Other languages
English (en)
Inventor
Maria Candida Cesta
Roberto Curti
Luca Nicolini
Marco Mantovanini
Original Assignee
Dompe Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Spa filed Critical Dompe Spa
Priority to IT1998MI002480A priority Critical patent/IT1303759B1/it
Priority to AU64845/99A priority patent/AU6484599A/en
Priority to PCT/IB1999/001834 priority patent/WO2000029411A1/en
Priority to HU0104278A priority patent/HUP0104278A3/hu
Priority to EP99952758A priority patent/EP1149098A1/en
Priority to JP2000582398A priority patent/JP2002530282A/ja
Publication of ITMI982480A1 publication Critical patent/ITMI982480A1/it
Application granted granted Critical
Publication of IT1303759B1 publication Critical patent/IT1303759B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT1998MI002480A 1998-11-17 1998-11-17 Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico. IT1303759B1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT1998MI002480A IT1303759B1 (it) 1998-11-17 1998-11-17 Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.
AU64845/99A AU6484599A (en) 1998-11-17 1999-11-12 An improved process for the preparation of 7-azaindolyl-3-carboxylic acid
PCT/IB1999/001834 WO2000029411A1 (en) 1998-11-17 1999-11-12 An improved process for the preparation of 7-azaindolyl-3-carboxylic acid
HU0104278A HUP0104278A3 (en) 1998-11-17 1999-11-12 Novel process for the preparation of 7-azaindolyl-3-carboxylic acid and 7-azaindol and their intermediates
EP99952758A EP1149098A1 (en) 1998-11-17 1999-11-12 An improved process for the preparation of 7-azaindolyl-3-carboxylic acid
JP2000582398A JP2002530282A (ja) 1998-11-17 1999-11-12 改良された7−アザインドリル−3−カルボン酸の製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002480A IT1303759B1 (it) 1998-11-17 1998-11-17 Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.

Publications (2)

Publication Number Publication Date
ITMI982480A1 ITMI982480A1 (it) 2000-05-17
IT1303759B1 true IT1303759B1 (it) 2001-02-23

Family

ID=11381069

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002480A IT1303759B1 (it) 1998-11-17 1998-11-17 Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.

Country Status (6)

Country Link
EP (1) EP1149098A1 (it)
JP (1) JP2002530282A (it)
AU (1) AU6484599A (it)
HU (1) HUP0104278A3 (it)
IT (1) IT1303759B1 (it)
WO (1) WO2000029411A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10305372B4 (de) 2003-02-10 2009-01-08 Continental Automotive Gmbh Vorrichtung und Verfahren zum Erkennen von Fehlern in einem einen Kraftstoffdruckdämpfer aufweisenden Kraftstoffeinspritzsystem
CN1925855B (zh) 2003-12-19 2010-06-16 普莱希科公司 开发Ret调节剂的化合物和方法
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
MX2010000617A (es) 2007-07-17 2010-05-17 Plexxikon Inc Compuestos y metodos para modulacion de cinasa, e indicaciones de estos.
EA031116B1 (ru) 2009-04-03 2018-11-30 Ф. Хоффманн-Ля Рош Аг КРИСТАЛЛИЧЕСКИЕ ПОЛИМОРФНЫЕ ФОРМЫ {3-[5-(4-ХЛОРФЕНИЛ)-1H-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ
UA105813C2 (uk) 2009-11-06 2014-06-25 Плексікон, Інк. Сполуки-інгібітори кіназ та фармацевтична композиція (варіанти)
PL2672967T3 (pl) 2011-02-07 2019-04-30 Plexxikon Inc Związki i sposoby modulacji kinaz i wskazania ku temu
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
JP6911062B2 (ja) * 2016-07-01 2021-07-28 フェルミオン オサケ ユキチュア ベムラフェニブの新規な製造方法

Also Published As

Publication number Publication date
AU6484599A (en) 2000-06-05
HUP0104278A2 (hu) 2002-04-29
ITMI982480A1 (it) 2000-05-17
HUP0104278A3 (en) 2002-06-28
WO2000029411A1 (en) 2000-05-25
JP2002530282A (ja) 2002-09-17
EP1149098A1 (en) 2001-10-31

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