MA34948B1 - Composes et procedes de modulation de kinase, et leurs indications - Google Patents

Composes et procedes de modulation de kinase, et leurs indications

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Publication number
MA34948B1
MA34948B1 MA36213A MA36213A MA34948B1 MA 34948 B1 MA34948 B1 MA 34948B1 MA 36213 A MA36213 A MA 36213A MA 36213 A MA36213 A MA 36213A MA 34948 B1 MA34948 B1 MA 34948B1
Authority
MA
Morocco
Prior art keywords
compounds
methods
indications
modulating kinase
kinase
Prior art date
Application number
MA36213A
Other languages
English (en)
Inventor
Prabha N Ibrahim
Chao Zhang
Wayne Spevak
Jiazhong Zhang
Guoxian Wu
Jack Lin
Hanna Cho
Marika Nespi
Songyuan Shi
Todd Ewing
Ying Zhang
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46638904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA34948(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of MA34948B1 publication Critical patent/MA34948B1/fr

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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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Abstract

L'invention concerne des composés actifs sur des protéines kinases, ainsi que des procédés de fabrication et d'utilisation de tels composés pour traiter des maladies et des états associés à une activité aberrante de protéines kinases.
MA36213A 2011-02-07 2012-02-01 Composes et procedes de modulation de kinase, et leurs indications MA34948B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161440339P 2011-02-07 2011-02-07
PCT/US2012/023543 WO2012109075A1 (fr) 2011-02-07 2012-02-01 Composés et procédés de modulation de kinase, et leurs indications

Publications (1)

Publication Number Publication Date
MA34948B1 true MA34948B1 (fr) 2014-03-01

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ID=46638904

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36213A MA34948B1 (fr) 2011-02-07 2012-02-01 Composes et procedes de modulation de kinase, et leurs indications

Country Status (35)

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US (3) US9624213B2 (fr)
EP (1) EP2672967B1 (fr)
JP (3) JP5941069B2 (fr)
KR (1) KR101911972B1 (fr)
CN (1) CN103517710B (fr)
AR (1) AR085316A1 (fr)
AU (1) AU2012214762B2 (fr)
BR (1) BR112013020041B1 (fr)
CA (1) CA2826123C (fr)
CL (1) CL2013002228A1 (fr)
CO (1) CO6781514A2 (fr)
CR (1) CR20130374A (fr)
CY (1) CY1121511T1 (fr)
DK (1) DK2672967T3 (fr)
EA (1) EA028821B9 (fr)
EC (1) ECSP13012869A (fr)
ES (1) ES2696023T3 (fr)
HR (1) HRP20181779T1 (fr)
HU (1) HUE040136T2 (fr)
IL (1) IL227698B (fr)
LT (1) LT2672967T (fr)
MA (1) MA34948B1 (fr)
MX (1) MX358128B (fr)
MY (1) MY162950A (fr)
PE (1) PE20141360A1 (fr)
PL (1) PL2672967T3 (fr)
PT (1) PT2672967T (fr)
RS (1) RS58455B1 (fr)
SG (1) SG192686A1 (fr)
SI (1) SI2672967T1 (fr)
TR (1) TR201816421T4 (fr)
TW (1) TWI640521B (fr)
UY (1) UY33899A (fr)
WO (1) WO2012109075A1 (fr)
ZA (1) ZA201305856B (fr)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063888A2 (fr) 2006-11-22 2008-05-29 Plexxikon, Inc. Composés modulant l'activité de c-fms et/ou de c-kit et utilisations associées
WO2009012283A1 (fr) 2007-07-17 2009-01-22 Plexxikon Inc. Composés et procédés pour la modulation des kinases et leurs indications
US8158636B2 (en) 2008-05-19 2012-04-17 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
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AR085316A1 (es) 2013-09-25
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