ATE184008T1 - Pyrrolopyridinderivate als dopaminrezeptor liganden - Google Patents

Pyrrolopyridinderivate als dopaminrezeptor liganden

Info

Publication number
ATE184008T1
ATE184008T1 AT94906978T AT94906978T ATE184008T1 AT E184008 T1 ATE184008 T1 AT E184008T1 AT 94906978 T AT94906978 T AT 94906978T AT 94906978 T AT94906978 T AT 94906978T AT E184008 T1 ATE184008 T1 AT E184008T1
Authority
AT
Austria
Prior art keywords
pct
dopamine receptor
image
receptor ligands
pyrrolopyridine derivatives
Prior art date
Application number
AT94906978T
Other languages
English (en)
Inventor
Raymond Baker
Neil Roy Curtis
Janusz Jozef Kulagowski
Paul David Leeson
Adrian Leonard Smith
Mark Peter Ridgill
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939304110A external-priority patent/GB9304110D0/en
Priority claimed from GB939316260A external-priority patent/GB9316260D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE184008T1 publication Critical patent/ATE184008T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94906978T 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden ATE184008T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939304110A GB9304110D0 (en) 1993-03-01 1993-03-01 Therapeutic agents
GB939316260A GB9316260D0 (en) 1993-08-05 1993-08-05 Therapeutic agents

Publications (1)

Publication Number Publication Date
ATE184008T1 true ATE184008T1 (de) 1999-09-15

Family

ID=26302518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906978T ATE184008T1 (de) 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden

Country Status (4)

Country Link
US (1) US5700809A (de)
AT (1) ATE184008T1 (de)
DE (1) DE69420394T2 (de)
ES (1) ES2134929T3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605065D0 (en) * 1996-03-11 1996-05-08 Merck Sharp & Dohme Therapeutic agents
US20070066641A1 (en) * 2003-12-19 2007-03-22 Prabha Ibrahim Compounds and methods for development of RET modulators
CA2550361C (en) * 2003-12-19 2014-04-29 Prabha Ibrahim Compounds and methods for development of ret modulators
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
AU2005265017A1 (en) * 2004-06-17 2006-01-26 Plexxikon, Inc. Azaindoles modulating c-kit activity and uses therefor
DE102004060659A1 (de) * 2004-12-15 2006-07-06 Lanxess Deutschland Gmbh Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung
MX2007014377A (es) * 2005-05-17 2008-02-06 Plexxikon Inc Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina.
CN101193894A (zh) * 2005-06-09 2008-06-04 马林克罗特公司 通过制备色谱法分离和纯化纳曲酮的方法
BRPI0611863B1 (pt) 2005-06-22 2021-11-23 Plexxikon, Inc Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
RU2009122670A (ru) 2006-12-21 2011-01-27 Плекссикон, Инк. (Us) Соединения и способы для модуляции киназ и показания к их применению
EP2170830B1 (de) 2007-07-17 2014-10-15 Plexxikon, Inc. 2-FLUORO-BENZOSULFONAMID-VERBINDUNGEN ALS Raf-KINASE-MODULATOREN
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
BR112012012156A2 (pt) 2009-11-06 2015-09-08 Plexxikon Inc compostos e métodos para modulação de cinase, e indicações para esta
TR201816421T4 (tr) 2011-02-07 2018-11-21 Plexxikon Inc Kinaz modülasyonu için bileşikler ve metotlar ve bunların endikasyonları.
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US20210236663A1 (en) * 2019-12-18 2021-08-05 Chdi Foundation, Inc. Compounds and probes for imaging huntingtin protein

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2044254B (en) * 1979-01-26 1983-01-26 Wyeth John & Brother Ltd Piperidine derivatives
US5124335A (en) * 1991-01-30 1992-06-23 Merck & Co., Inc. Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists
US5622950A (en) * 1993-03-01 1997-04-22 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
US5576319A (en) * 1993-03-01 1996-11-19 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
PL310443A1 (en) * 1993-03-01 1995-12-11 Merck Sharp & Dohme Derivatives of pyrolo-pyridine
GB9416189D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
GB9416162D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
AU699196B2 (en) * 1994-08-10 1998-11-26 Merck Sharp & Dohme Limited Tetrahydropyridinylmethyl derivatives of pyrrolo 2,3-b pyridine

Also Published As

Publication number Publication date
DE69420394D1 (de) 1999-10-07
DE69420394T2 (de) 2000-04-13
ES2134929T3 (es) 1999-10-16
US5700809A (en) 1997-12-23

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Legal Events

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