ATE184008T1 - Pyrrolopyridinderivate als dopaminrezeptor liganden - Google Patents

Pyrrolopyridinderivate als dopaminrezeptor liganden

Info

Publication number
ATE184008T1
ATE184008T1 AT94906978T AT94906978T ATE184008T1 AT E184008 T1 ATE184008 T1 AT E184008T1 AT 94906978 T AT94906978 T AT 94906978T AT 94906978 T AT94906978 T AT 94906978T AT E184008 T1 ATE184008 T1 AT E184008T1
Authority
AT
Austria
Prior art keywords
pct
dopamine receptor
image
receptor ligands
pyrrolopyridine derivatives
Prior art date
Application number
AT94906978T
Other languages
English (en)
Inventor
Raymond Baker
Neil Roy Curtis
Janusz Jozef Kulagowski
Paul David Leeson
Adrian Leonard Smith
Mark Peter Ridgill
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939304110A external-priority patent/GB9304110D0/en
Priority claimed from GB939316260A external-priority patent/GB9316260D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE184008T1 publication Critical patent/ATE184008T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94906978T 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden ATE184008T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939304110A GB9304110D0 (en) 1993-03-01 1993-03-01 Therapeutic agents
GB939316260A GB9316260D0 (en) 1993-08-05 1993-08-05 Therapeutic agents

Publications (1)

Publication Number Publication Date
ATE184008T1 true ATE184008T1 (de) 1999-09-15

Family

ID=26302518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906978T ATE184008T1 (de) 1993-03-01 1994-02-25 Pyrrolopyridinderivate als dopaminrezeptor liganden

Country Status (4)

Country Link
US (1) US5700809A (de)
AT (1) ATE184008T1 (de)
DE (1) DE69420394T2 (de)
ES (1) ES2134929T3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605065D0 (en) * 1996-03-11 1996-05-08 Merck Sharp & Dohme Therapeutic agents
CN1925855B (zh) * 2003-12-19 2010-06-16 普莱希科公司 开发Ret调节剂的化合物和方法
US20070066641A1 (en) * 2003-12-19 2007-03-22 Prabha Ibrahim Compounds and methods for development of RET modulators
CA2570817A1 (en) * 2004-06-17 2006-01-26 Plexxikon, Inc. Azaindoles modulating c-kit activity and uses therefor
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
DE102004060659A1 (de) * 2004-12-15 2006-07-06 Lanxess Deutschland Gmbh Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung
MX2007014377A (es) * 2005-05-17 2008-02-06 Plexxikon Inc Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina.
WO2006135650A1 (en) * 2005-06-09 2006-12-21 Mallinckrodt Inc. Method for separation and purification of naltrexone by preparative chromatography
PL2395004T3 (pl) * 2005-06-22 2016-08-31 Plexxikon Inc Pochodne pirolo[2,3-b]pirydyny jako inhibitory kinazy białkowej
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
US7872018B2 (en) 2006-12-21 2011-01-18 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
PE20081581A1 (es) * 2006-12-21 2008-11-12 Plexxikon Inc COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA
MX2010000617A (es) 2007-07-17 2010-05-17 Plexxikon Inc Compuestos y metodos para modulacion de cinasa, e indicaciones de estos.
EA031116B1 (ru) 2009-04-03 2018-11-30 Ф. Хоффманн-Ля Рош Аг КРИСТАЛЛИЧЕСКИЕ ПОЛИМОРФНЫЕ ФОРМЫ {3-[5-(4-ХЛОРФЕНИЛ)-1H-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
UA105813C2 (uk) 2009-11-06 2014-06-25 Плексікон, Інк. Сполуки-інгібітори кіназ та фармацевтична композиція (варіанти)
PL2672967T3 (pl) 2011-02-07 2019-04-30 Plexxikon Inc Związki i sposoby modulacji kinaz i wskazania ku temu
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
JP7720847B2 (ja) 2019-12-18 2025-08-08 シーエイチディーアイ ファウンデーション，インコーポレーテッド ハンチンチンタンパク質をイメージングするための化合物及びプローブ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2044254B (en) * 1979-01-26 1983-01-26 Wyeth John & Brother Ltd Piperidine derivatives
US5124335A (en) * 1991-01-30 1992-06-23 Merck & Co., Inc. Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists
US5622950A (en) * 1993-03-01 1997-04-22 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
CZ224195A3 (en) * 1993-03-01 1996-03-13 Merck Sharp & Dohme The use of pyrrolopyridine derivatives for preparing pharmaceutical preparations
US5576319A (en) * 1993-03-01 1996-11-19 Merck, Sharp & Dohme Ltd. Pyrrolo-pyridine derivatives
GB9416189D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
GB9416162D0 (en) * 1994-08-10 1994-09-28 Merck Sharp & Dohme Therapeutic agents
US5830901A (en) * 1994-08-10 1998-11-03 Merch Sharp & Dohme Ltd Tetrahydropyridinylmethyl derivatives of pyrrolo 2,3-B!pyridine

Also Published As

Publication number Publication date
US5700809A (en) 1997-12-23
ES2134929T3 (es) 1999-10-16
DE69420394T2 (de) 2000-04-13
DE69420394D1 (de) 1999-10-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties