|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
|
US20110239315A1
(en)
|
2009-01-12 |
2011-09-29 |
Ulla Bonas |
Modular dna-binding domains and methods of use
|
|
CA2765488C
(en)
*
|
2009-06-30 |
2018-01-02 |
Sangamo Biosciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
|
CN106834320B
(zh)
|
2009-12-10 |
2021-05-25 |
明尼苏达大学董事会 |
Tal效应子介导的dna修饰
|
|
US20110203012A1
(en)
*
|
2010-01-21 |
2011-08-18 |
Dotson Stanton B |
Methods and compositions for use of directed recombination in plant breeding
|
|
EP2660318A1
(en)
*
|
2010-02-09 |
2013-11-06 |
Sangamo BioSciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
|
SG185367A1
(en)
*
|
2010-04-26 |
2012-12-28 |
Sangamo Biosciences Inc |
Genome editing of a rosa locus using zinc-finger nucleases
|
|
JP6208580B2
(ja)
*
|
2010-05-17 |
2017-10-04 |
サンガモ セラピューティクス, インコーポレイテッド |
新規のdna結合タンパク質及びその使用
|
|
CN105671108A
(zh)
|
2010-06-02 |
2016-06-15 |
沃维公司 |
甜菊糖苷的重组生产
|
|
EP2392208B1
(en)
*
|
2010-06-07 |
2016-05-04 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use
|
|
EP2580331A4
(en)
*
|
2010-06-14 |
2013-11-27 |
Univ Iowa State Res Found Inc |
NUCLEASE ACTIVITY OF THE TAL EFFECTOR AND FUSION PROTEIN FOKI
|
|
JP6050230B2
(ja)
|
2010-07-21 |
2016-12-21 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Hla遺伝子座の修飾のための方法及び組成物
|
|
US20240397918A1
(en)
*
|
2011-02-25 |
2024-12-05 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
WO2012116274A2
(en)
|
2011-02-25 |
2012-08-30 |
Recombinetics, Inc. |
Genetically modified animals and methods for making the same
|
|
CA3111953C
(en)
*
|
2011-04-05 |
2023-10-24 |
Cellectis |
Method for the generation of compact tale-nucleases and uses thereof
|
|
SG194089A1
(en)
|
2011-04-27 |
2013-11-29 |
Amyris Inc |
Methods for genomic modification
|
|
CN103597082B
(zh)
|
2011-06-06 |
2017-09-15 |
拜尔作物科学公司 |
用于在预选位点修饰植物基因组的方法和手段
|
|
US20140274812A1
(en)
|
2011-07-15 |
2014-09-18 |
The General Hospital Corporation |
Methods of Transcription Activator Like Effector Assembly
|
|
EP3613852A3
(en)
|
2011-07-22 |
2020-04-22 |
President and Fellows of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
EP2737063B1
(en)
|
2011-07-25 |
2016-06-01 |
Sangamo BioSciences, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
|
EP2736538A4
(en)
*
|
2011-07-27 |
2015-08-05 |
Broad Inst Inc |
COMPOSITIONS AND METHOD FOR TREATING HEADS AND HALSTUMORS
|
|
US20140309145A1
(en)
*
|
2011-07-29 |
2014-10-16 |
Cellectis Sa |
High throughput method for assembly and cloning polynucleotides comprising highly similar polynucleotidic modules
|
|
WO2013019745A1
(en)
*
|
2011-07-29 |
2013-02-07 |
Georgia Health Sciences University |
Methods and compositions for genetically modifiying cells
|
|
CN102787125B
(zh)
*
|
2011-08-05 |
2013-12-04 |
北京大学 |
一种构建tale重复序列的方法
|
|
WO2013022989A2
(en)
|
2011-08-08 |
2013-02-14 |
Evolva Sa |
Recombinant production of steviol glycosides
|
|
CN103890181A
(zh)
|
2011-08-22 |
2014-06-25 |
拜尔作物科学公司 |
修饰植物基因组的方法和手段
|
|
CA2848417C
(en)
|
2011-09-21 |
2023-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of transgene expression
|
|
WO2013050611A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013050318A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013050593A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013053686A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013053711A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
EP2766486A1
(en)
|
2011-10-12 |
2014-08-20 |
Bayer CropScience AG |
Plants with decreased activity of a starch dephosphorylating enzyme
|
|
BR112014008895A2
(pt)
|
2011-10-12 |
2019-09-24 |
Bayer Cropscience Ag |
plantas com atividade diminuída de uma enzima de desfosforilação do amido
|
|
US9513283B2
(en)
|
2011-10-21 |
2016-12-06 |
Kyushu University, National University Corporation |
Method for designing RNA binding protein utilizing PPR motif, and use thereof
|
|
CA3099582A1
(en)
*
|
2011-10-27 |
2013-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the hprt locus
|
|
BR112014010537A2
(pt)
|
2011-10-31 |
2017-05-02 |
Pioneer Hi Bred Int |
método para modular a sensibilidade ao etileno, planta transgênica, proteína isolada, sequência de polinucleotídeos isolada, polipeptídeo com atividade regulatória de etileno, método para aumentar o rendimento em uma planta, método para melhorar um parâmetro agronômico de uma planta, método de seleção assistida por marcador de uma planta
|
|
HK1200871A1
(en)
*
|
2011-11-16 |
2015-08-14 |
Sangamo Therapeutics, Inc. |
Modified dna-binding proteins and uses thereof
|
|
US20130137173A1
(en)
*
|
2011-11-30 |
2013-05-30 |
Feng Zhang |
Nucleotide-specific recognition sequences for designer tal effectors
|
|
US10801017B2
(en)
|
2011-11-30 |
2020-10-13 |
The Broad Institute, Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
|
US8450107B1
(en)
|
2011-11-30 |
2013-05-28 |
The Broad Institute Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
|
CN111893140A
(zh)
|
2011-12-05 |
2020-11-06 |
菲克特生物科学股份有限公司 |
用于转染细胞的方法和产品
|
|
JP2015500648A
(ja)
|
2011-12-16 |
2015-01-08 |
ターゲットジーン バイオテクノロジーズ リミテッド |
所定の標的核酸配列を修飾するための組成物及び方法
|
|
DE102011122267A1
(de)
|
2011-12-23 |
2013-06-27 |
Kws Saat Ag |
Neue aus Pflanzen stammende cis-regulatorische Elemente für die Entwicklung Pathogen-responsiver chimärer Promotoren
|
|
US9688997B2
(en)
|
2011-12-29 |
2017-06-27 |
Iowa State University Research Foundation, Inc. |
Genetically modified plants with resistance to Xanthomonas and other bacterial plant pathogens
|
|
GB201122458D0
(en)
|
2011-12-30 |
2012-02-08 |
Univ Wageningen |
Modified cascade ribonucleoproteins and uses thereof
|
|
EP2612918A1
(en)
|
2012-01-06 |
2013-07-10 |
BASF Plant Science Company GmbH |
In planta recombination
|
|
CN104302773A
(zh)
|
2012-03-13 |
2015-01-21 |
圭尔夫大学 |
增加植物对热胁迫的耐受性及氨基酸含量的方法
|
|
US20150203864A1
(en)
|
2012-03-13 |
2015-07-23 |
University Of Guelph |
Myb55 promoter and use thereof
|
|
EP3141259B1
(en)
*
|
2012-03-15 |
2019-07-31 |
Cellectis |
Repeat variable diresidues for targeting nucleotides
|
|
SG10201607943RA
(en)
|
2012-03-23 |
2016-11-29 |
Cellectis |
Method to overcome dna chemical modifications sensitivity of engineered tale dna binding domains
|
|
CN102628037B
(zh)
*
|
2012-03-31 |
2013-07-24 |
西南大学 |
家蚕油蚕基因BmBlos2遗传改造系统及其制备方法和应用
|
|
WO2013152220A2
(en)
*
|
2012-04-04 |
2013-10-10 |
Life Technologies Corporation |
Tal-effector assembly platform, customized services, kits and assays
|
|
WO2013158309A2
(en)
|
2012-04-18 |
2013-10-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Non-disruptive gene targeting
|
|
BR112014026203A2
(pt)
|
2012-04-23 |
2017-07-18 |
Bayer Cropscience Nv |
engenharia do genoma direcionado nas plantas
|
|
CN104364380B
(zh)
|
2012-04-25 |
2018-10-09 |
瑞泽恩制药公司 |
核酸酶介导的使用大靶向载体的靶向
|
|
WO2013163628A2
(en)
|
2012-04-27 |
2013-10-31 |
Duke University |
Genetic correction of mutated genes
|
|
HK1208052A1
(en)
|
2012-05-02 |
2016-02-19 |
陶氏益农公司 |
Targeted modification of malate dehydrogenase
|
|
WO2013169802A1
(en)
|
2012-05-07 |
2013-11-14 |
Sangamo Biosciences, Inc. |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
|
WO2013169398A2
(en)
|
2012-05-09 |
2013-11-14 |
Georgia Tech Research Corporation |
Systems and methods for improving nuclease specificity and activity
|
|
US9605274B2
(en)
|
2012-05-25 |
2017-03-28 |
Evolutionary Genomics, Inc. |
Dirigent gene EG261 and its orthologs and paralogs and their uses for pathogen resistance in plants
|
|
HUE064187T2
(hu)
*
|
2012-05-25 |
2024-02-28 |
Cellectis |
Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására
|
|
RS59199B1
(sr)
*
|
2012-05-25 |
2019-10-31 |
Univ California |
Metode i jedinjenja za rnk-upravljanu ciljanu dnk modifikaciju i za rnk- upravljanu modulaciju transkripta
|
|
BR112014029381B1
(pt)
|
2012-05-25 |
2022-09-13 |
Eg Crop Science, Inc |
Método para produzir uma planta de soja recombinante, método para produzir semente de soja híbrida, método para reprodução de plantas de soja e constructo
|
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
|
US10815500B2
(en)
*
|
2012-06-05 |
2020-10-27 |
Cellectis |
Transcription activator-like effector (TALE) fusion protein
|
|
AU2013272283B2
(en)
|
2012-06-07 |
2018-02-15 |
The Children's Hospital Of Philadelphia |
Controlled gene expression methods
|
|
US20150128300A1
(en)
|
2012-06-12 |
2015-05-07 |
Genentech, Inc. |
Methods and compositions for generating conditional knock-out alleles
|
|
BR112014031260A2
(pt)
|
2012-06-15 |
2019-08-20 |
Du Pont |
métodos e composições que envolvem variantes de als com preferência de substrato nativo
|
|
US20150225734A1
(en)
*
|
2012-06-19 |
2015-08-13 |
Regents Of The University Of Minnesota |
Gene targeting in plants using dna viruses
|
|
AR091482A1
(es)
*
|
2012-06-21 |
2015-02-04 |
Recombinetics Inc |
Celulas modificadas geneticamente y metodos par su obtencion
|
|
US20150291951A1
(en)
*
|
2012-06-22 |
2015-10-15 |
Mayo Foundation For Medical Education And Research |
Genome editing
|
|
JP6293660B2
(ja)
|
2012-07-06 |
2018-03-14 |
国立研究開発法人農業・食品産業技術総合研究機構 |
着粒数が増加したコムギ及びその生産方法、並びにコムギの着粒数を増加させるための薬剤
|
|
CA2878037C
(en)
|
2012-07-11 |
2021-08-31 |
Sangamo Biosciences, Inc. |
Methods and compositions for delivery of biologics
|
|
ES2613691T3
(es)
|
2012-07-11 |
2017-05-25 |
Sangamo Biosciences, Inc. |
Métodos y composiciones para el tratamiento de enfermedades por almacenamiento lisosomal
|
|
US20150104873A1
(en)
*
|
2012-07-11 |
2015-04-16 |
University of Nevada, Las Vegas |
Genome Surgery with Paired, Permeant Endonuclease Construct
|
|
EP2687605A1
(en)
|
2012-07-19 |
2014-01-22 |
Biogemma |
Method for performing homologous recombination
|
|
EP2877488B1
(en)
|
2012-07-24 |
2021-02-24 |
Cellectis |
New modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins
|
|
EP3494997B1
(en)
*
|
2012-07-25 |
2019-09-18 |
The Broad Institute, Inc. |
Inducible dna binding proteins and genome perturbation tools and applications thereof
|
|
US10058078B2
(en)
|
2012-07-31 |
2018-08-28 |
Recombinetics, Inc. |
Production of FMDV-resistant livestock by allele substitution
|
|
AU2013308770B2
(en)
|
2012-08-29 |
2019-01-17 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treatment of a genetic condition
|
|
WO2014033556A2
(en)
*
|
2012-09-03 |
2014-03-06 |
Cellectis |
Methods for modulating tal specificity
|
|
US9902962B2
(en)
*
|
2012-09-04 |
2018-02-27 |
The Scripps Research Institute |
Chimeric polypeptides having targeted binding specificity
|
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
|
AU2013312538B2
(en)
|
2012-09-07 |
2019-01-24 |
Corteva Agriscience Llc |
FAD3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
|
|
WO2014043143A1
(en)
|
2012-09-11 |
2014-03-20 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
EP2895620B1
(en)
|
2012-09-11 |
2017-08-02 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
EP2906602B1
(en)
|
2012-10-12 |
2019-01-16 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
|
MX2015005255A
(es)
*
|
2012-10-30 |
2015-10-29 |
Recombinetics Inc |
Control de la maduracion sexual en animales.
|
|
WO2014071006A1
(en)
|
2012-10-31 |
2014-05-08 |
Cellectis |
Coupling herbicide resistance with targeted insertion of transgenes in plants
|
|
KR102315098B1
(ko)
|
2012-11-01 |
2021-10-21 |
팩터 바이오사이언스 인크. |
세포에서 단백질을 발현시키는 방법들과 생성물들
|
|
EP2914094B1
(en)
|
2012-11-01 |
2021-07-21 |
Cellectis |
Plants for production of therapeutic proteins
|
|
WO2014081729A1
(en)
*
|
2012-11-20 |
2014-05-30 |
J.R. Simplot Company |
Tal-mediated transfer dna insertion
|
|
JP2016500254A
(ja)
|
2012-12-05 |
2016-01-12 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
代謝疾患の調節のための方法および組成物
|
|
KR102479178B1
(ko)
|
2012-12-06 |
2022-12-19 |
시그마-알드리치 컴퍼니., 엘엘씨 |
Crispr-기초된 유전체 변형과 조절
|
|
WO2014093701A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
|
EP4299741A3
(en)
|
2012-12-12 |
2024-02-28 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
CN103013954B
(zh)
*
|
2012-12-17 |
2014-03-05 |
中国科学院遗传与发育生物学研究所 |
水稻基因badh2的定点敲除系统及其应用
|
|
US9708589B2
(en)
|
2012-12-18 |
2017-07-18 |
Monsanto Technology Llc |
Compositions and methods for custom site-specific DNA recombinases
|
|
PL2934097T3
(pl)
|
2012-12-21 |
2018-11-30 |
Cellectis |
Ziemniaki o ograniczonej słodkości indukowanej chłodem
|
|
CA2894213A1
(en)
|
2012-12-21 |
2014-06-26 |
Pioneer Hi-Bred International, Inc. |
Compositions and methods for auxin-analog conjugation
|
|
SG11201505597SA
(en)
|
2013-02-06 |
2015-08-28 |
Evolva Sa |
Methods for improved production of rebaudioside d and rebaudioside m
|
|
EP3623463B1
(en)
*
|
2013-02-07 |
2021-10-20 |
The General Hospital Corporation |
Tale transcriptional activators
|
|
EP2954061B1
(en)
|
2013-02-11 |
2023-11-22 |
Evolva SA |
Efficient production of steviol glycosides in recombinant hosts
|
|
CN103319574A
(zh)
*
|
2013-02-16 |
2013-09-25 |
清华大学 |
分离的多肽及其应用
|
|
EP3561050B1
(en)
|
2013-02-20 |
2021-12-08 |
Regeneron Pharmaceuticals, Inc. |
Genetic modification of rats
|
|
WO2014128659A1
(en)
|
2013-02-21 |
2014-08-28 |
Cellectis |
Method to counter-select cells or organisms by linking loci to nuclease components
|
|
EP2958996B1
(en)
|
2013-02-25 |
2019-10-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
|
ES2750550T3
(es)
*
|
2013-03-01 |
2020-03-26 |
Univ Minnesota |
Corrección de gen a base de TALEN
|
|
CN105473721A
(zh)
|
2013-03-11 |
2016-04-06 |
先锋国际良种公司 |
采用磺酰脲类依赖型稳定化结构域的方法和组合物
|
|
EP2970935A1
(en)
|
2013-03-14 |
2016-01-20 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
|
US20140287419A1
(en)
|
2013-03-14 |
2014-09-25 |
Arzeda Corp. |
Compositions Having Dicamba Decarboxylase Activity and Methods of Use
|
|
NZ712727A
(en)
|
2013-03-14 |
2017-05-26 |
Caribou Biosciences Inc |
Compositions and methods of nucleic acid-targeting nucleic acids
|
|
US10793867B2
(en)
|
2013-03-15 |
2020-10-06 |
Monsanto Technology, Llc |
Methods for targeted transgene-integration using custom site-specific DNA recombinases
|
|
US10113162B2
(en)
|
2013-03-15 |
2018-10-30 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes
|
|
WO2014144094A1
(en)
*
|
2013-03-15 |
2014-09-18 |
J.R. Simplot Company |
Tal-mediated transfer dna insertion
|
|
US11039586B2
(en)
|
2013-03-15 |
2021-06-22 |
Monsanto Technology Llc |
Creation and transmission of megaloci
|
|
EP2966983B1
(en)
|
2013-03-15 |
2021-07-28 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the fad2-1a/1b genes
|
|
AU2014227831B2
(en)
*
|
2013-03-15 |
2020-01-30 |
Regents Of The University Of Minnesota |
Engineering plant genomes using CRISPR/Cas systems
|
|
US9828582B2
(en)
|
2013-03-19 |
2017-11-28 |
Duke University |
Compositions and methods for the induction and tuning of gene expression
|
|
US20160053274A1
(en)
|
2013-04-02 |
2016-02-25 |
Bayer Cropscience Nv |
Targeted genome engineering in eukaryotes
|
|
WO2014165612A2
(en)
|
2013-04-05 |
2014-10-09 |
Dow Agrosciences Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
|
MX369747B
(es)
|
2013-04-16 |
2019-11-20 |
Regeneron Pharma |
Modificación dirigida del genoma de rata.
|
|
HK1214302A1
(zh)
*
|
2013-04-16 |
2016-07-22 |
深圳华大基因科技服务有限公司 |
分离的寡核苷酸及其用途
|
|
CN105392796A
(zh)
|
2013-04-22 |
2016-03-09 |
国立大学法人九州大学 |
利用ppr基序的dna结合性蛋白质及其应用
|
|
EP2796558A1
(en)
|
2013-04-23 |
2014-10-29 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Improved gene targeting and nucleic acid carrier molecule, in particular for use in plants
|
|
CN103233004B
(zh)
*
|
2013-04-28 |
2015-04-29 |
新疆农垦科学院 |
一种人工dna分子及检测目标基因表达的方法
|
|
WO2014186435A2
(en)
|
2013-05-14 |
2014-11-20 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for reducing neointima formation
|
|
JP2016521561A
(ja)
|
2013-06-14 |
2016-07-25 |
セレクティス |
植物における非トランスジェニックのゲノム編集のための方法
|
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
|
EP3011033B1
(en)
|
2013-06-17 |
2020-02-19 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof
|
|
BR112015031608A2
(pt)
|
2013-06-17 |
2017-08-22 |
Massachusetts Inst Technology |
Aplicação e uso dos sistemas crispr-cas, vetores e composições para direcionamento e terapia hepáticos
|
|
EP2818867A1
(en)
|
2013-06-27 |
2014-12-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies conjugated to at least one nucleic acid molecule and their use in multiplex immuno-detection assays
|
|
WO2015002780A1
(en)
*
|
2013-07-01 |
2015-01-08 |
The Board Of Regents Of The University Of Texas System |
Transcription activator-like effector (tale) libraries and methods of synthesis and use
|
|
US10563225B2
(en)
|
2013-07-26 |
2020-02-18 |
President And Fellows Of Harvard College |
Genome engineering
|
|
ES2915377T3
(es)
|
2013-08-02 |
2022-06-22 |
Enevolv Inc |
Procedimientos y células huésped para ingeniería genómica, de vías y biomolécular
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
JP5931022B2
(ja)
|
2013-08-09 |
2016-06-08 |
国立大学法人広島大学 |
Dna結合ドメインを含むポリペプチド
|
|
US10006011B2
(en)
|
2013-08-09 |
2018-06-26 |
Hiroshima University |
Polypeptide containing DNA-binding domain
|
|
EP4353078A3
(de)
|
2013-09-04 |
2025-01-08 |
KWS SAAT SE & Co. KGaA |
Helminthosporium turcicum-resistente pflanze
|
|
DE102013014637A1
(de)
|
2013-09-04 |
2015-03-05 |
Kws Saat Ag |
HELMlNTHOSPORlUM TURClCUM-RESlSTENTE PFLANZE
|
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
|
IL312865B2
(en)
|
2013-09-11 |
2025-06-01 |
Eagle Biologics Inc |
Liquid protein formulations containing viscosity-lowering agents
|
|
RU2670512C2
(ru)
*
|
2013-09-23 |
2018-10-23 |
Ренссилэйер Политекник Инститьют |
Доставка генов, опосредованная наночастицами, геномная коррекция и лиганд-направленная модификация в различных клеточных популяциях
|
|
AU2014334590A1
(en)
|
2013-10-18 |
2016-04-28 |
Pioneer Hi-Bred International, Inc. |
Glyphosate-N-acetyltransferase (GLYAT) sequences and methods of use
|
|
EP3060682B1
(en)
|
2013-10-25 |
2023-08-30 |
Livestock Improvement Corporation Limited |
Genetic markers and uses therefor
|
|
JP2016535781A
(ja)
|
2013-11-03 |
2016-11-17 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
経皮薬物送達のためのイオン性液体
|
|
JP6633532B2
(ja)
|
2013-11-04 |
2020-01-22 |
ダウ アグロサイエンシィズ エルエルシー |
最適なトウモロコシ遺伝子座
|
|
WO2015066636A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal maize loci
|
|
NZ735257A
(en)
|
2013-11-04 |
2018-09-28 |
Dow Agrosciences Llc |
Optimal soybean loci
|
|
WO2015066634A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal soybean loci
|
|
EP3865575A1
(en)
|
2013-11-06 |
2021-08-18 |
Hiroshima University |
Vector for nucleic acid insertion
|
|
US11326209B2
(en)
*
|
2013-11-07 |
2022-05-10 |
Massachusetts Institute Of Technology |
Cell-based genomic recorded accumulative memory
|
|
EP2878667A1
(en)
|
2013-11-29 |
2015-06-03 |
Institut Pasteur |
TAL effector means useful for partial or full deletion of DNA tandem repeats
|
|
CN103710360A
(zh)
*
|
2013-12-03 |
2014-04-09 |
南方医科大学珠江医院 |
提高HepGL肝癌细胞氨基甲酰磷酸合成酶表达的方法
|
|
EP4349980A3
(en)
|
2013-12-11 |
2024-06-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a genome
|
|
RU2685914C1
(ru)
|
2013-12-11 |
2019-04-23 |
Регенерон Фармасьютикалс, Инк. |
Способы и композиции для направленной модификации генома
|
|
WO2015089486A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
|
EP3653703A1
(en)
|
2013-12-12 |
2020-05-20 |
The Broad Institute, Inc. |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
|
EP3080259B1
(en)
|
2013-12-12 |
2023-02-01 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
|
SG10201804975PA
(en)
|
2013-12-12 |
2018-07-30 |
Broad Inst Inc |
Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for HBV and Viral Diseases and Disorders
|
|
WO2015089462A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for genome editing
|
|
WO2015089375A1
(en)
|
2013-12-13 |
2015-06-18 |
The General Hospital Corporation |
Soluble high molecular weight (hmw) tau species and applications thereof
|
|
WO2015092460A1
(en)
|
2013-12-18 |
2015-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New gene mutations for the diagnosis of arthrogryposis multiplex congenita and congenital peripheral neuropathies disease
|
|
PT3083958T
(pt)
|
2013-12-19 |
2019-06-27 |
Amyris Inc |
Métodos de integração genómica
|
|
WO2015116969A2
(en)
*
|
2014-01-30 |
2015-08-06 |
The Board Of Trustees Of The University Of Arkansas |
Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
|
|
EP3690056B1
(en)
|
2014-01-31 |
2022-12-28 |
Factor Bioscience Inc. |
Methods and products for nucleic acid production and delivery
|
|
LT3102673T
(lt)
|
2014-02-03 |
2020-08-25 |
Sangamo Therapeutics, Inc. |
Beta talasemijos gydymo būdai ir kompozicijos
|
|
CN104844696A
(zh)
*
|
2014-02-19 |
2015-08-19 |
北京大学 |
一种转录激活子样效应因子功能蛋白设计、合成及其应用
|
|
TW201538518A
(zh)
|
2014-02-28 |
2015-10-16 |
Dow Agrosciences Llc |
藉由嵌合基因調控元件所賦予之根部特異性表現
|
|
EP3613854A1
(en)
*
|
2014-03-05 |
2020-02-26 |
National University Corporation Kobe University |
Genomic sequence modification method for specifically converting nucleic acid bases of targeted dna sequence, and molecular complex for use in same
|
|
KR102736149B1
(ko)
|
2014-03-21 |
2024-11-28 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
뉴클레아제 없는 게놈 편집
|
|
WO2015148761A1
(en)
|
2014-03-26 |
2015-10-01 |
University Of Maryland, College Park |
Targeted genome editing in zygotes of domestic large animals
|
|
US10507232B2
(en)
*
|
2014-04-02 |
2019-12-17 |
University Of Florida Research Foundation, Incorporated |
Materials and methods for the treatment of latent viral infection
|
|
WO2015164748A1
(en)
|
2014-04-24 |
2015-10-29 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (tale) proteins
|
|
CN111647627A
(zh)
|
2014-04-28 |
2020-09-11 |
重组股份有限公司 |
多重基因编辑
|
|
WO2015165276A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒
|
|
CN104611365B
(zh)
*
|
2014-07-17 |
2017-06-16 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
|
WO2015165275A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
|
DE102014106327A1
(de)
|
2014-05-07 |
2015-11-12 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
TAL-Effektornuklease zum gezielten Knockout des HIV-Korezeptors CCR5
|
|
US11918695B2
(en)
|
2014-05-09 |
2024-03-05 |
Yale University |
Topical formulation of hyperbranched polymer-coated particles
|
|
ES3007997T3
(en)
|
2014-05-09 |
2025-03-21 |
Univ Yale |
Hyperbranched polyglycerol-coated particles
|
|
CA2947622A1
(en)
|
2014-05-13 |
2015-11-19 |
Sangamo Biosciences, Inc. |
Genome editing methods and compositions for prevention or treatment of a disease
|
|
HUE049776T2
(hu)
|
2014-06-06 |
2020-10-28 |
Regeneron Pharma |
Módszerek és készítmények egy célzott lókusz módosítására
|
|
EA201692565A1
(ru)
|
2014-06-12 |
2017-05-31 |
Сесвандерхаве Н.В. |
Способ трансформации протопластов сахарной свеклы на платформе технологии talen
|
|
WO2015188870A1
(en)
|
2014-06-12 |
2015-12-17 |
Sesvanderhave N.V. |
Use of selectable marker gene in sugar beet protoplasts transformation method and system
|
|
CA2952906A1
(en)
|
2014-06-20 |
2015-12-23 |
Cellectis |
Potatoes with reduced granule-bound starch synthase
|
|
DK3354732T3
(da)
|
2014-06-23 |
2020-04-06 |
Regeneron Pharma |
Nukleasemedieret dna-samling
|
|
WO2015200805A2
(en)
|
2014-06-26 |
2015-12-30 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modifications and methods of use
|
|
WO2016000237A1
(en)
|
2014-07-03 |
2016-01-07 |
Pioneer Overseas Corporation |
Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
|
|
AU2015298571B2
(en)
|
2014-07-30 |
2020-09-03 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
EP3179869A1
(en)
|
2014-08-11 |
2017-06-21 |
Evolva SA |
Production of steviol glycosides in recombinant hosts
|
|
WO2016025759A1
(en)
|
2014-08-14 |
2016-02-18 |
Shen Yuelei |
Dna knock-in system
|
|
CN105367628B
(zh)
*
|
2014-08-19 |
2019-07-26 |
深圳华大基因农业控股有限公司 |
一对高效编辑水稻waxy基因的talen其识别打靶位点及其应用
|
|
CN105367631B
(zh)
*
|
2014-08-25 |
2019-05-14 |
深圳华大基因科技有限公司 |
一种转录激活子样效应因子核酸酶及其编码基因和应用
|
|
KR20170045344A
(ko)
|
2014-09-07 |
2017-04-26 |
셀렉타 바이오사이언시즈, 인크. |
항-바이러스 전달 벡터 면역 반응을 약화시키기 위한 방법 및 조성물
|
|
US10612064B2
(en)
|
2014-09-09 |
2020-04-07 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
KR101528812B1
(ko)
*
|
2014-09-18 |
2015-06-15 |
강원대학교산학협력단 |
SETDB1 HMTase 발현 저해방법
|
|
CN105440111B
(zh)
*
|
2014-09-30 |
2019-08-13 |
深圳华大基因研究院 |
一对转录激活子样效应因子核酸酶及其编码序列与应用
|
|
CA2962768C
(en)
|
2014-10-01 |
2023-10-10 |
Alyssa M. Larson |
Polysaccharide and nucleic acid formulations containing viscosity-lowering agents
|
|
CN104357440B
(zh)
*
|
2014-10-09 |
2017-06-13 |
中山大学 |
一对靶向斑马鱼Forkhead box n1基因的Talen识别序列及其mRNA制备方法
|
|
US20180250424A1
(en)
|
2014-10-10 |
2018-09-06 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
|
PT3207124T
(pt)
|
2014-10-15 |
2019-08-27 |
Regeneron Pharma |
Métodos e composições para a produção ou conservação de células pluripotentes
|
|
WO2016066671A1
(en)
|
2014-10-29 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating resistant cancers using progastrin inhibitors
|
|
EP3739047A1
(en)
|
2014-11-04 |
2020-11-18 |
National University Corporation Kobe University |
Method for modifying genome sequence to introduce specific mutation to targeted dna sequence by base-removal reaction, and molecular complex used therein
|
|
CN107532142A
(zh)
*
|
2014-11-11 |
2018-01-02 |
应用干细胞有限公司 |
使用同源重组改造间充质干细胞
|
|
WO2016077429A1
(en)
|
2014-11-12 |
2016-05-19 |
Recombinetics, Inc. |
Heterozygous modifications of tumor suppressor genes and swine model of neurofibromatosis type 1
|
|
DE102014016667B4
(de)
|
2014-11-12 |
2024-03-07 |
Kws Saat Se |
Haploideninduktoren
|
|
US20160138040A1
(en)
*
|
2014-11-13 |
2016-05-19 |
Cellectis |
Brassica engineered to confer herbicide tolerance
|
|
EP3985115A1
(en)
|
2014-12-12 |
2022-04-20 |
The Broad Institute, Inc. |
Protected guide rnas (pgrnas)
|
|
WO2016100333A1
(en)
|
2014-12-15 |
2016-06-23 |
Syngenta Participations Ag |
Pesticidal microrna carriers and use thereof
|
|
RU2707137C2
(ru)
|
2014-12-19 |
2019-11-22 |
Регенерон Фармасьютикалз, Инк. |
Способы и композиции для нацеленной генетической модификации посредством одноэтапного множественного нацеливания
|
|
CN107109427B
(zh)
|
2014-12-23 |
2021-06-18 |
先正达参股股份有限公司 |
用于鉴定和富集包含位点特异性基因组修饰的细胞的方法和组合物
|
|
CA2970370A1
(en)
|
2014-12-24 |
2016-06-30 |
Massachusetts Institute Of Technology |
Crispr having or associated with destabilization domains
|
|
US10752905B2
(en)
|
2015-01-20 |
2020-08-25 |
Mayo Foundation For Medical Education And Research |
Methods and materials for assembling nucleic acid constructs
|
|
CN114058582A
(zh)
|
2015-01-26 |
2022-02-18 |
菲特治疗公司 |
用于诱导造血细胞分化的方法和组合物
|
|
CN108337892B
(zh)
|
2015-01-30 |
2022-06-24 |
埃沃尔瓦公司 |
在重组宿主中生产甜菊醇糖苷
|
|
AU2016214048A1
(en)
|
2015-02-02 |
2017-08-24 |
Cellectis |
Agrobacterium-mediated genome modification without T-DNA integration
|
|
US10485196B2
(en)
|
2015-02-03 |
2019-11-26 |
The Institute Of Genetics And Developmental Biology Chinese Academy Of Scinces |
Rice plants with altered seed phenotype and quality
|
|
WO2016124918A1
(en)
|
2015-02-03 |
2016-08-11 |
The Institute Of Genetics And Developmental Biology |
Plants with increased seed size
|
|
WO2016130600A2
(en)
|
2015-02-09 |
2016-08-18 |
Duke University |
Compositions and methods for epigenome editing
|
|
WO2016128523A1
(en)
|
2015-02-12 |
2016-08-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the responsiveness of a patient affected with malignant hematological disease to chemotherapy treatment and methods of treatment of such disease
|
|
CA2976376A1
(en)
|
2015-02-13 |
2016-08-18 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
JP6590333B2
(ja)
*
|
2015-02-26 |
2019-10-16 |
学校法人東京理科大学 |
Dna結合ドメイン組込み用ベクターおよびそのセット、融合タンパク質コーディングベクターおよびそのセットならびにその製造方法、デスティネーションベクター、植物細胞用発現ベクターおよびその製造方法、植物細胞用発現ベクター作製用キット、形質転換方法、ならびにゲノム編集方法
|
|
EP3265560B1
(en)
|
2015-03-02 |
2021-12-08 |
Sinai Health System |
Homologous recombination factors
|
|
WO2016142427A1
(en)
|
2015-03-10 |
2016-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method ank kit for reprogramming somatic cells
|
|
US10604743B2
(en)
|
2015-03-16 |
2020-03-31 |
Dsm Ip Assets B.V. |
UDP-glycosyltransferases
|
|
AU2016239037B2
(en)
*
|
2015-03-16 |
2022-04-21 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Method of applying non-genetic substance to perform site-directed reform of plant genome
|
|
KR101675023B1
(ko)
*
|
2015-03-26 |
2016-11-10 |
한국생명공학연구원 |
표적 유전자 특이적 핵산 프로브 및 FokⅠ 제한효소 이량체를 이용하여 세포 내에서 표적 유전자를 특이적으로 편집하기 위한 조성물 및 이의 용도
|
|
WO2016161004A1
(en)
*
|
2015-03-30 |
2016-10-06 |
The Board Of Regents Of The Nevada System Of Higher Educ. On Behalf Of The University Of Nevada, La |
Compositions comprising talens and methods of treating hiv
|
|
US20180094243A1
(en)
|
2015-04-03 |
2018-04-05 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
|
EP4008780A1
(en)
|
2015-04-30 |
2022-06-08 |
The Trustees of Columbia University in the City of New York |
Gene therapy for autosomal dominant diseases
|
|
EP3292219B9
(en)
|
2015-05-04 |
2022-05-18 |
Ramot at Tel-Aviv University Ltd. |
Methods and kits for fragmenting dna
|
|
EP3095870A1
(en)
|
2015-05-19 |
2016-11-23 |
Kws Saat Se |
Methods for the in planta transformation of plants and manufacturing processes and products based and obtainable therefrom
|
|
JP7107683B2
(ja)
|
2015-06-18 |
2022-07-27 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
オフターゲット効果を低下させるcrispr酵素突然変異
|
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
|
ES2594486B1
(es)
|
2015-06-19 |
2017-09-26 |
Biopraxis Research Aie |
Molécula de ácido nucleico, proteína de fusión y método para modificar el material genético de una célula
|
|
CA2991054C
(en)
|
2015-06-30 |
2024-03-12 |
Regents Of The University Of Minnesota |
Haploid inducer line for accelerated genome editing
|
|
US10988775B2
(en)
|
2015-07-17 |
2021-04-27 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Wheat plants resistant to powdery mildew
|
|
CA2997535A1
(en)
*
|
2015-07-23 |
2017-01-26 |
Mayo Foundation For Medical Education And Research |
Editing mitochondrial dna
|
|
CN108271391A
(zh)
|
2015-08-07 |
2018-07-10 |
埃沃尔瓦公司 |
重组宿主中的甜菊醇糖苷的产生
|
|
AU2016308339A1
(en)
|
2015-08-18 |
2018-04-12 |
Baylor College Of Medicine |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
|
US10898522B2
(en)
|
2015-08-19 |
2021-01-26 |
Children's Research Institute, Children's National Medical Center |
Compositions and methods for treating graft versus host disease
|
|
US10767173B2
(en)
|
2015-09-09 |
2020-09-08 |
National University Corporation Kobe University |
Method for converting genome sequence of gram-positive bacterium by specifically converting nucleic acid base of targeted DNA sequence, and molecular complex used in same
|
|
US10837024B2
(en)
|
2015-09-17 |
2020-11-17 |
Cellectis |
Modifying messenger RNA stability in plant transformations
|
|
WO2017066497A2
(en)
|
2015-10-13 |
2017-04-20 |
Duke University |
Genome engineering with type i crispr systems in eukaryotic cells
|
|
EP3362074B1
(en)
|
2015-10-16 |
2023-08-09 |
President and Fellows of Harvard College |
Regulatory t cell pd-1 modulation for regulating t cell effector immune responses
|
|
US12043852B2
(en)
|
2015-10-23 |
2024-07-23 |
President And Fellows Of Harvard College |
Evolved Cas9 proteins for gene editing
|
|
KR20180091821A
(ko)
|
2015-10-27 |
2018-08-16 |
리컴비네틱스 인코포레이티드 |
유전적 상보성에 의한 인간화 car t-세포 및 혈소판의 조작방법
|
|
US12194080B2
(en)
|
2015-10-29 |
2025-01-14 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using PM20D1 and N-lipidated amino acids
|
|
CN115806940A
(zh)
|
2015-11-04 |
2023-03-17 |
菲特治疗公司 |
多能细胞的基因组工程改造
|
|
WO2017079428A1
(en)
|
2015-11-04 |
2017-05-11 |
President And Fellows Of Harvard College |
Site specific germline modification
|
|
EP3371301A4
(en)
|
2015-11-04 |
2019-06-26 |
Fate Therapeutics, Inc. |
METHOD AND COMPOSITIONS FOR INDUCING THE DIFFERENTIATION OF HEMATOPOIETIC CELLS
|
|
AU2016355178B9
(en)
|
2015-11-19 |
2019-05-30 |
Massachusetts Institute Of Technology |
Lymphocyte antigen CD5-like (CD5L)-interleukin 12B (p40) heterodimers in immunity
|
|
EP3173485B1
(de)
|
2015-11-27 |
2021-08-25 |
KWS SAAT SE & Co. KGaA |
Kühletolerante pflanze
|
|
DK3382019T3
(da)
|
2015-11-27 |
2022-05-30 |
Univ Kobe Nat Univ Corp |
Fremgangsmåde til omdannelse af enkimet plantegenomsekvens, hvori nukleinsyrebase i målrettet DNA-sekvens specifikt omdannes, og molekylært kompleks anvendt deri
|
|
EP3384055B1
(en)
|
2015-11-30 |
2025-07-16 |
Duke University |
Therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use
|
|
WO2017106537A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the mhc cell receptor
|
|
WO2017106528A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the t cell receptor
|
|
DE102015017161A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
|
US11840693B2
(en)
|
2015-12-21 |
2023-12-12 |
KWS SAAT SE & Co. KGaA |
Restorer plants
|
|
DE102015016445A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
|
EP3402885A4
(en)
|
2016-01-11 |
2019-07-03 |
The Board of Trustees of the Leland Stanford Junior University |
CHIMERIC PROTEINS AND METHOD FOR REGULATING GENE EXPRESSION
|
|
EA201891614A1
(ru)
|
2016-01-11 |
2019-02-28 |
Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити |
Химерные белки и способы иммунотерапии
|
|
EP4646936A3
(en)
|
2016-02-02 |
2025-11-19 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes
|
|
JP2019508037A
(ja)
|
2016-02-16 |
2019-03-28 |
イェール ユニバーシティーYale Universit |
標的化遺伝子編集を増強するための組成物およびその使用方法
|
|
WO2017143061A1
(en)
|
2016-02-16 |
2017-08-24 |
Yale University |
Compositions and methods for treatment of cystic fibrosis
|
|
US20190249172A1
(en)
|
2016-02-18 |
2019-08-15 |
The Regents Of The University Of California |
Methods and compositions for gene editing in stem cells
|
|
EP3416663B1
(en)
|
2016-02-18 |
2021-04-14 |
The Penn State Research Foundation |
Generating gabaergic neurons in brains
|
|
EP3420093B1
(en)
|
2016-02-26 |
2022-11-23 |
Cellectis |
Micelle based system nuclease encapsulation for in-vivo gene editing
|
|
WO2017161043A1
(en)
|
2016-03-16 |
2017-09-21 |
The J. David Gladstone Institutes |
Methods and compositions for treating obesity and/or diabetes and for identifying candidate treatment agents
|
|
KR20190080825A
(ko)
|
2016-03-21 |
2019-07-08 |
다나-파버 캔서 인스티튜트 인크. |
T-세포 기능소실 상태-특이적 유전자 발현 조절인자 및 그 용도
|
|
CA3018729A1
(en)
|
2016-03-23 |
2017-09-28 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
|
WO2017173453A1
(en)
|
2016-04-01 |
2017-10-05 |
The Brigham And Women's Hospital, Inc. |
Stimuli-responsive nanoparticles for biomedical applications
|
|
WO2017178632A1
(en)
|
2016-04-13 |
2017-10-19 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
US20190062734A1
(en)
|
2016-04-13 |
2019-02-28 |
Editas Medicine, Inc. |
Grna fusion molecules, gene editing systems, and methods of use thereof
|
|
US20190127713A1
(en)
|
2016-04-13 |
2019-05-02 |
Duke University |
Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
|
|
CN109121413A
(zh)
*
|
2016-04-14 |
2019-01-01 |
弗莱德哈钦森癌症研究中心 |
使用靶向核酸纳米载体编程治疗性细胞的组合物和方法
|
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
US10894093B2
(en)
|
2016-04-15 |
2021-01-19 |
Cellectis |
Method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation
|
|
CN107312788B
(zh)
*
|
2016-04-26 |
2020-07-28 |
中国科学院动物研究所 |
一种tale重复序列载体的构建方法
|
|
WO2017192573A1
(en)
|
2016-05-02 |
2017-11-09 |
Massachusetts Institute Of Technology |
Nanoparticle conjugates of highly potent toxins and intraperitoneal administration of nanoparticles for treating or imaging cancer
|
|
EP3458599A1
(en)
|
2016-05-16 |
2019-03-27 |
Evolva SA |
Production of steviol glycosides in recombinant hosts
|
|
US11293033B2
(en)
|
2016-05-18 |
2022-04-05 |
Amyris, Inc. |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
|
|
CN105950623B
(zh)
*
|
2016-05-19 |
2018-11-30 |
电子科技大学 |
一种用于talen高效构建的双rvd单元模块库及talen构建方法
|
|
BR112018074101A2
(pt)
|
2016-05-26 |
2019-03-06 |
Nunhems Bv |
plantas produtoras de fruto sem semente
|
|
US11293021B1
(en)
|
2016-06-23 |
2022-04-05 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
|
US11471462B2
(en)
|
2016-06-27 |
2022-10-18 |
The Broad Institute, Inc. |
Compositions and methods for detecting and treating diabetes
|
|
CA3029271A1
(en)
|
2016-06-28 |
2018-01-04 |
Cellectis |
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
|
|
CN105949293B
(zh)
*
|
2016-06-28 |
2019-08-13 |
福建农林大学 |
植物源高效转录激活功能域sac3及应用
|
|
JP7195154B2
(ja)
|
2016-07-06 |
2022-12-23 |
セレクティス |
初代免疫細胞における逐次遺伝子編集
|
|
US11674158B2
(en)
|
2016-07-15 |
2023-06-13 |
Salk Institute For Biological Studies |
Methods and compositions for genome editing in non-dividing cells
|
|
EP3487523B1
(en)
|
2016-07-19 |
2023-09-06 |
Duke University |
Therapeutic applications of cpf1-based genome editing
|
|
SG11201901305YA
(en)
|
2016-07-29 |
2019-03-28 |
Regeneron Pharma |
Mice comprising mutations resulting in expression of c-truncated fibrillin-1
|
|
GB2568182A
(en)
|
2016-08-03 |
2019-05-08 |
Harvard College |
Adenosine nucleobase editors and uses thereof
|
|
WO2018031683A1
(en)
|
2016-08-09 |
2018-02-15 |
President And Fellows Of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
KR20190038613A
(ko)
|
2016-08-11 |
2019-04-08 |
더 잭슨 래보라토리 |
유전자 변형된 면역결핍 비-인간 동물에서의 개선된 인간 적혈구 생존에 관한 방법 및 조성물
|
|
AU2017312113B2
(en)
|
2016-08-17 |
2023-05-25 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
UY40583A
(es)
|
2016-08-17 |
2024-01-15 |
Monsanto Technology Llc |
MÉTODOS, COMPOSICIONES y PLANTAS MEDIANTE LA MANIPULACIÓN DEL METABOLISMO DE GIBERELINA PARA AUMENTAR EL RENDIMIENTO COSECHABLE
|
|
WO2018035456A1
(en)
|
2016-08-18 |
2018-02-22 |
Cellectis |
Black-spot resistant potatoes with reduced tuber-specific polyphenol oxidase activity
|
|
WO2018039448A1
(en)
|
2016-08-24 |
2018-03-01 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
EP3503927B1
(en)
|
2016-08-29 |
2025-02-19 |
The Regents of the University of California |
Topical formulations based on ionic species for skin treatment
|
|
US20200002709A1
(en)
|
2016-09-01 |
2020-01-02 |
Cellectis |
Methods for altering amino acid content in plants
|
|
EP3509645A4
(en)
|
2016-09-07 |
2020-06-17 |
Sangamo Therapeutics, Inc. |
MODULATION OF LIVER GENES
|
|
US11136409B2
(en)
|
2016-09-20 |
2021-10-05 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of AML using USP10 biomarkers and modulators
|
|
US20180084767A1
(en)
|
2016-09-21 |
2018-03-29 |
Recombinetics, Inc. |
Animal models for cardiomyopathy
|
|
US20190225974A1
(en)
|
2016-09-23 |
2019-07-25 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome optimization in plants
|
|
WO2018064208A1
(en)
|
2016-09-28 |
2018-04-05 |
The Broad Institute, Inc. |
Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof
|
|
EP3757120B8
(en)
|
2016-10-04 |
2022-06-15 |
Precision Biosciences, Inc. |
Co-stimulatory domains for use in genetically-modified cells
|
|
US11873325B2
(en)
|
2016-10-10 |
2024-01-16 |
Limagrain Europe |
Nucleic acid encoding Sm1 resistance to orange wheat blossom midge and method of use
|
|
WO2018069232A1
(en)
|
2016-10-10 |
2018-04-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of having cardiac hypertrophy
|
|
GB2573062A
(en)
|
2016-10-14 |
2019-10-23 |
Harvard College |
AAV delivery of nucleobase editors
|
|
GB201617559D0
(en)
|
2016-10-17 |
2016-11-30 |
University Court Of The University Of Edinburgh The |
Swine comprising modified cd163 and associated methods
|
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
|
WO2018081081A1
(en)
|
2016-10-24 |
2018-05-03 |
Javier Gil Humanes |
Multiplex gene targeting in plants
|
|
WO2018076335A1
(en)
|
2016-10-31 |
2018-05-03 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Compositions and methods for enhancing abiotic stress tolerance
|
|
WO2018144097A1
(en)
|
2016-11-04 |
2018-08-09 |
Akeagen Llc |
Genetically modified non-human animals and methods for producing heavy chain-only antibodies
|
|
WO2018083338A1
(en)
|
2016-11-07 |
2018-05-11 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
WO2018089386A1
(en)
|
2016-11-11 |
2018-05-17 |
The Broad Institute, Inc. |
Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action
|
|
UY37482A
(es)
|
2016-11-16 |
2018-05-31 |
Cellectis |
Métodos para alterar el contenido de aminoácidos en plantas mediante mutaciones de desplazamiento de marco
|
|
US20200029538A1
(en)
|
2016-11-28 |
2020-01-30 |
Osaka University |
Genome editing method
|
|
US10519456B2
(en)
|
2016-12-02 |
2019-12-31 |
Syngenta Participations Ag |
Simultaneous gene editing and haploid induction
|
|
WO2018112282A1
(en)
|
2016-12-14 |
2018-06-21 |
Ligandal, Inc. |
Compositions and methods for nucleic acid and/or protein payload delivery
|
|
US20200085758A1
(en)
|
2016-12-16 |
2020-03-19 |
The Brigham And Women's Hospital, Inc. |
Co-delivery of nucleic acids for simultaneous suppression and expression of target genes
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
WO2018123938A1
(ja)
*
|
2016-12-27 |
2018-07-05 |
国立研究開発法人農業・食品産業技術総合研究機構 |
ゲノム編集植物の作出方法
|
|
JP7348063B2
(ja)
|
2017-01-05 |
2023-09-20 |
フレッド ハッチンソン キャンサー センター |
ワクチン効力を改善するためのシステム及び方法
|
|
GB201700380D0
(en)
|
2017-01-10 |
2017-02-22 |
Plant Bioscience Ltd |
Methods of increasing seed yield
|
|
WO2018136702A1
(en)
|
2017-01-23 |
2018-07-26 |
Regeneron Pharmaceuticals, Inc. |
Hydroxysteroid 17-beta dehydrogenase 13 (hsd17b13) variants and uses thereof
|
|
WO2018140497A1
(en)
|
2017-01-25 |
2018-08-02 |
Efimov Igor R |
Apparatus and methods for in vitro preclinical human trials
|
|
CN110573623A
(zh)
|
2017-02-09 |
2019-12-13 |
福建农林大学 |
用于提高植物产量的磷酸盐转运蛋白的表达
|
|
CN119351474A
(zh)
|
2017-02-22 |
2025-01-24 |
克里斯珀医疗股份公司 |
用于基因编辑的组合物和方法
|
|
EP3366778A1
(de)
|
2017-02-28 |
2018-08-29 |
Kws Saat Se |
Haploidisierung in sorghum
|
|
US11307139B2
(en)
|
2017-03-03 |
2022-04-19 |
Pioneer Hi-Bred International, Inc. |
Non-destructive assay for soybean seeds using near infrared analysis
|
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
WO2018165631A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Cancer vaccine
|
|
CN110914310A
(zh)
|
2017-03-10 |
2020-03-24 |
哈佛大学的校长及成员们 |
胞嘧啶至鸟嘌呤碱基编辑器
|
|
US11957115B2
(en)
|
2017-03-21 |
2024-04-16 |
The Jackson Laboratory |
Genetically modified mouse expressing human APOE4 and mouse Trem2 p.R47H and methods of use thereof
|
|
JP7133856B2
(ja)
|
2017-03-22 |
2022-09-09 |
国立大学法人神戸大学 |
細胞内在性のdna修飾酵素を利用して標的化したdnaの核酸塩基を特異的に変換する、細胞の核酸配列の変換方法、及びそれに用いる分子複合体
|
|
US11268082B2
(en)
|
2017-03-23 |
2022-03-08 |
President And Fellows Of Harvard College |
Nucleobase editors comprising nucleic acid programmable DNA binding proteins
|
|
US12161694B2
(en)
|
2017-03-24 |
2024-12-10 |
The Broad Institute, Inc. |
Methods and compositions for regulating innate lymphoid cell inflammatory responses
|
|
WO2018172785A1
(en)
|
2017-03-24 |
2018-09-27 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Methods for increasing grain yield
|
|
US10980779B2
(en)
|
2017-03-24 |
2021-04-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
GFI1 inhibitors for the treatment of hyperglycemia
|
|
EP3604521A4
(en)
|
2017-03-30 |
2021-05-19 |
The University of Tokyo |
MULTIPLE GENES OF DIFFERENT INTEREST EVALUATION PROCESS
|
|
WO2018183908A1
(en)
|
2017-03-31 |
2018-10-04 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
WO2018187493A1
(en)
|
2017-04-04 |
2018-10-11 |
Yale University |
Compositions and methods for in utero delivery
|
|
EP3610266A4
(en)
|
2017-04-12 |
2021-04-21 |
Massachusetts Eye and Ear Infirmary |
TUMOR SIGNATURE FOR METASTASIS, COMPOSITIONS OF MATERIAL AND THEIR METHODS OF USE
|
|
WO2018191520A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Respiratory and sweat gland ionocytes
|
|
EP3392339A1
(en)
|
2017-04-18 |
2018-10-24 |
Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen |
Improved genome editing in plant cells
|
|
KR102746223B1
(ko)
|
2017-04-20 |
2024-12-27 |
이제네시스, 인크. |
유전자 변형 동물의 생성 방법
|
|
EP3612232A1
(en)
|
2017-04-21 |
2020-02-26 |
The Broad Institute, Inc. |
Targeted delivery to beta cells
|
|
ES2977620T3
(es)
|
2017-04-25 |
2024-08-27 |
Cellectis |
Alfalfa con composición reducida de lignina
|
|
CA3061612A1
(en)
|
2017-04-28 |
2018-11-01 |
Acuitas Therapeutics, Inc. |
Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
RU2019139045A
(ru)
|
2017-05-03 |
2021-06-03 |
Сангамо Терапьютикс, Инк. |
Способы и композиции для модификации гена регулятора трансмембранной проводимости при кистозном фиброзе (cftr)
|
|
US11591601B2
(en)
|
2017-05-05 |
2023-02-28 |
The Broad Institute, Inc. |
Methods for identification and modification of lncRNA associated with target genotypes and phenotypes
|
|
AU2018266698A1
(en)
|
2017-05-08 |
2019-11-28 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
|
WO2018209324A2
(en)
|
2017-05-11 |
2018-11-15 |
The Broad Institute, Inc. |
Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
JP7129426B2
(ja)
|
2017-05-12 |
2022-09-01 |
ザ ジャクソン ラボラトリー |
Mhcクラスiおよびmhcクラスiiを欠損しているnsgマウス
|
|
WO2018211032A1
(en)
|
2017-05-17 |
2018-11-22 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
WO2018215779A1
(en)
|
2017-05-25 |
2018-11-29 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Methods for increasing grain productivity
|
|
EP3409104A1
(en)
|
2017-05-31 |
2018-12-05 |
Vilmorin et Cie |
Tomato plant resistant to tomato yellow leaf curl virus, powdery mildew, and nematodes
|
|
WO2020249996A1
(en)
|
2019-06-14 |
2020-12-17 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus
|
|
EP3409106A1
(en)
|
2017-06-01 |
2018-12-05 |
Vilmorin et Cie |
Tolerance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus (tbrfv)
|
|
WO2018224508A1
(en)
|
2017-06-05 |
2018-12-13 |
Consejo Superior De Investigaciones Científicas (Csic) -Delegación Andalucía |
Targeting of gluten by genome editing
|
|
AU2018282072B2
(en)
|
2017-06-05 |
2024-06-27 |
Regeneron Pharmaceuticals, Inc. |
B4GALT1 variants and uses thereof
|
|
WO2018226685A2
(en)
|
2017-06-06 |
2018-12-13 |
Dana-Farber Cancer Institute, Inc. |
Methods for sensitizing cancer cells to t cell-mediated killing by modulating molecular pathways
|
|
WO2018231999A1
(en)
|
2017-06-13 |
2018-12-20 |
Regents Of The University Of Minnesota |
Materials and methods for increasing gene editing frequency
|
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
MX2019015188A
(es)
|
2017-06-15 |
2020-08-03 |
Univ California |
Inserciones de adn no virales orientadas.
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
EP3641785A1
(en)
|
2017-06-19 |
2020-04-29 |
Cellectis |
Anti-hbv combination therapies involving specific endonucleases
|
|
EP3538645B1
(en)
|
2017-06-20 |
2021-01-20 |
Institut Curie |
Immune cells defective for suv39h1
|
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
WO2018237107A1
(en)
|
2017-06-23 |
2018-12-27 |
University Of Kentucky Research Foundation |
Method
|
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
EP3645054A4
(en)
|
2017-06-26 |
2021-03-31 |
The Broad Institute, Inc. |
CRISPR / CAS-ADENINE DESAMINASE COMPOSITIONS, TARGETED NUCLEIC ACID EDITING SYSTEMS AND METHODS
|
|
WO2019005957A1
(en)
|
2017-06-30 |
2019-01-03 |
Precision Biosciences, Inc. |
GENETICALLY MODIFIED T CELLS COMPRISING A MODIFIED INTRON IN THE ALPHA T CELL RECEPTOR GENE
|
|
WO2019006436A1
(en)
|
2017-06-30 |
2019-01-03 |
Inscripta, Inc. |
METHODS, MODULES, INSTRUMENTS AND SYSTEMS FOR AUTOMATED CELL PROCESSING
|
|
WO2019014489A1
(en)
|
2017-07-12 |
2019-01-17 |
Mayo Foundation For Medical Education And Research |
MATERIALS AND METHODS FOR EFFICIENT TARGETED KNOCK-IN OR GENE REPLACEMENT
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
WO2019018440A1
(en)
|
2017-07-17 |
2019-01-24 |
The Broad Institute, Inc. |
HUMAN COLON CELL ATLAS IN GOOD HEALTH AND WITH HEMORRHAGIC RECTO-COLITIS
|
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
|
EP3663310A4
(en)
*
|
2017-08-04 |
2021-08-11 |
Peking University |
TALE RVD SPECIFICALLY RECOGNIZING A DNA BASE MODIFIED BY METHYLATION AND CORRESPONDING APPLICATION
|
|
US20190045761A1
(en)
|
2017-08-11 |
2019-02-14 |
Recombinetics, Inc. |
Inducible disease models methods of making them and use in tissue complementation
|
|
EP3447134B1
(en)
|
2017-08-22 |
2023-10-11 |
KWS SAAT SE & Co. KGaA |
Increased fungal resistance in crop plants
|
|
US20190136249A1
(en)
|
2017-08-22 |
2019-05-09 |
Napigen, Inc. |
Organelle genome modification using polynucleotide guided endonuclease
|
|
WO2019038417A1
(en)
|
2017-08-25 |
2019-02-28 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
METHODS FOR INCREASING GRAIN YIELD
|
|
US10738327B2
(en)
|
2017-08-28 |
2020-08-11 |
Inscripta, Inc. |
Electroporation cuvettes for automation
|
|
AU2018325363B2
(en)
|
2017-08-29 |
2025-01-23 |
Global Crop Innovations Pty. Ltd. |
Improved BLue Aleurone and other segregation systems
|
|
WO2019139645A2
(en)
|
2017-08-30 |
2019-07-18 |
President And Fellows Of Harvard College |
High efficiency base editors comprising gam
|
|
BR112020005217A2
(pt)
|
2017-09-18 |
2020-09-15 |
Amyris, Inc. |
métodos para a engenharia genética de células hospedeiras de kluyveromyces
|
|
BR112020005166A2
(pt)
|
2017-09-18 |
2020-09-24 |
Amyris, Inc. |
métodos para integração genômica para células hospedeiras de kluyveromyces
|
|
WO2019060759A1
(en)
|
2017-09-21 |
2019-03-28 |
Dana-Farber Cancer Institute, Inc. |
ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF PLANT EXTRACTS JUSTICIA
|
|
EP4276185A3
(en)
|
2017-09-29 |
2024-02-21 |
Regeneron Pharmaceuticals, Inc. |
Rodents comprising a humanized ttr locus and methods of use
|
|
WO2019068022A1
(en)
|
2017-09-30 |
2019-04-04 |
Inscripta, Inc. |
CONTINUOUS FLOW ELECTROPORATION INSTRUMENTATION
|
|
US20200239544A1
(en)
|
2017-10-03 |
2020-07-30 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
|
US20200255828A1
(en)
|
2017-10-04 |
2020-08-13 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
|
BR112020007157A2
(pt)
|
2017-10-13 |
2020-09-24 |
Selecta Biosciences, Inc. |
métodos e composições para a atenuação de respostas de igm antivetor de transferência viral
|
|
CA3082251A1
(en)
|
2017-10-16 |
2019-04-25 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
|
WO2019076486A1
(en)
|
2017-10-19 |
2019-04-25 |
Cellectis |
TARGETED GENE INTEGRATION OF NK INHIBITOR GENES FOR ENHANCED IMMUNE CELL THERAPY
|
|
AU2018355587B2
(en)
|
2017-10-27 |
2023-02-02 |
The Regents Of The University Of California |
Targeted replacement of endogenous T cell receptors
|
|
AU2018357926B2
(en)
|
2017-10-31 |
2023-04-06 |
Limagrain Europe |
Wheat comprising male fertility restorer alleles
|
|
WO2019089913A1
(en)
|
2017-11-01 |
2019-05-09 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER BY TARGETING THE CLEC2D-KLRB1 PATH
|
|
US12221720B2
(en)
|
2017-11-13 |
2025-02-11 |
The Broad Institute, Inc. |
Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
|
|
US12171783B2
(en)
|
2017-11-13 |
2024-12-24 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in H3K27M gliomas
|
|
WO2019100053A1
(en)
|
2017-11-20 |
2019-05-23 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for modulating hif-2α to improve muscle generation and repair
|
|
WO2019106163A1
(en)
|
2017-12-01 |
2019-06-06 |
Cellectis |
Reprogramming of genetically engineered primary immune cells
|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
CN112119085B
(zh)
|
2017-12-15 |
2025-04-01 |
丹娜-法伯癌症研究院有限公司 |
稳定肽-介导的靶向蛋白降解
|
|
CA3084572A1
(en)
|
2017-12-18 |
2019-06-27 |
Syngenta Participations Ag |
Targeted insertion sites in the maize genome
|
|
EP3501268B1
(en)
|
2017-12-22 |
2021-09-15 |
KWS SAAT SE & Co. KGaA |
Regeneration of plants in the presence of histone deacetylase inhibitors
|
|
SG11202005173SA
(en)
|
2017-12-22 |
2020-06-29 |
Fate Therapeutics Inc |
Enhanced immune effector cells and use thereof
|
|
CN107868123B
(zh)
|
2017-12-25 |
2020-05-12 |
中国农业科学院作物科学研究所 |
一种同时提高植物产量和抗性的基因及其应用
|
|
EP3508581A1
(en)
|
2018-01-03 |
2019-07-10 |
Kws Saat Se |
Regeneration of genetically modified plants
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
BR112020014168A2
(pt)
|
2018-01-12 |
2020-12-08 |
Basf Se |
Proteína, ácido nucleico isolado, gene recombinante, vetor, célula hospedeira, planta, parte de planta ou semente de trigo, métodos para produzir, produto de trigo, farinha, farelo integral, amido, grânulos de amido ou farelo de trigo e métodos para identificar e/ou selecionar uma planta de trigo
|
|
BR112020014242A2
(pt)
|
2018-02-14 |
2020-12-15 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Métodos de aumento da eficiência de uso de nutriente
|
|
CN111727257A
(zh)
|
2018-02-15 |
2020-09-29 |
孟山都技术公司 |
通过性状堆叠提高作物产量的组合物和方法
|
|
EP3751987A4
(en)
|
2018-02-15 |
2021-11-10 |
Monsanto Technology LLC |
IMPROVED METHODS FOR MANUFACTURING HYBRID CORN SEEDS
|
|
CN112384204B
(zh)
|
2018-02-26 |
2023-03-14 |
安托瑞斯公司 |
致耐受性脂质体及其使用方法
|
|
US20210062203A1
(en)
|
2018-03-12 |
2021-03-04 |
Pioneer Hi-Bred International, Inc. |
Methods for plant transformation
|
|
EP3768327A4
(en)
|
2018-03-23 |
2022-04-13 |
The Trustees of Columbia University in the City of New York |
GENE EDITING FOR AUTOSOMAL DOMINANT DISEASES
|
|
SG11202009319YA
(en)
|
2018-03-26 |
2020-10-29 |
Univ Kobe Nat Univ Corp |
Method for modifying target site in double-stranded dna in cell
|
|
EP3545756A1
(en)
|
2018-03-28 |
2019-10-02 |
KWS SAAT SE & Co. KGaA |
Regeneration of plants in the presence of inhibitors of the histone methyltransferase ezh2
|
|
EP3749762A1
(en)
|
2018-03-29 |
2020-12-16 |
Cellectis |
Tale-nucleases for allele-specific codon modification
|
|
WO2019190874A1
(en)
|
2018-03-29 |
2019-10-03 |
Inscripta, Inc. |
Automated control of cell growth rates for induction and transformation
|
|
EP3775228A4
(en)
|
2018-03-29 |
2022-02-23 |
Fate Therapeutics, Inc. |
ENHANCED IMMUNE EFFECTIVE CELLS AND THEIR USE
|
|
KR20200141470A
(ko)
|
2018-04-06 |
2020-12-18 |
칠드런'즈 메디컬 센터 코포레이션 |
체세포 재프로그래밍 및 각인의 조정을 위한 조성물 및 방법
|
|
MX2020010094A
(es)
|
2018-04-06 |
2021-01-15 |
Dana Farber Cancer Inst Inc |
Kir3dl3 como receptor de hhla2, anticuerpos anti-hhla2 y usos de estos.
|
|
GB201805865D0
(en)
|
2018-04-09 |
2018-05-23 |
Innes John Centre |
Genes
|
|
WO2019200004A1
(en)
|
2018-04-13 |
2019-10-17 |
Inscripta, Inc. |
Automated cell processing instruments comprising reagent cartridges
|
|
EP3781677A4
(en)
|
2018-04-16 |
2022-01-19 |
University of Massachusetts |
COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING
|
|
JP2021523733A
(ja)
|
2018-04-18 |
2021-09-09 |
アルティウス インスティテュート フォー バイオメディカル サイエンスィズ |
動物病原体由来ポリペプチドおよびその遺伝子工学的利用
|
|
PL3560330T3
(pl)
|
2018-04-24 |
2022-09-19 |
KWS SAAT SE & Co. KGaA |
Rośliny o ulepszonej strawności i haplotypach markerowych
|
|
US10557216B2
(en)
|
2018-04-24 |
2020-02-11 |
Inscripta, Inc. |
Automated instrumentation for production of T-cell receptor peptide libraries
|
|
US10858761B2
(en)
|
2018-04-24 |
2020-12-08 |
Inscripta, Inc. |
Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
|
|
WO2019209926A1
(en)
|
2018-04-24 |
2019-10-31 |
Inscripta, Inc. |
Automated instrumentation for production of peptide libraries
|
|
TWI686477B
(zh)
*
|
2018-04-25 |
2020-03-01 |
國立成功大學 |
特異性造成植物葉綠體基因變異的轉殖載體、套組、方法及利用其產生之轉殖植物細胞與農桿菌
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
US12281301B2
(en)
|
2018-04-27 |
2025-04-22 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
|
EP3788154A1
(en)
|
2018-05-02 |
2021-03-10 |
Cellectis |
Engineering wheat with increased dietary fiber
|
|
US20210386829A1
(en)
|
2018-05-04 |
2021-12-16 |
The Broad Institute, Inc. |
Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
|
|
HRP20251258T1
(hr)
|
2018-05-09 |
2025-12-05 |
KWS SAAT SE & Co. KGaA |
Gen za rezistenciju na patogen roda heterodera
|
|
SG11202011080QA
(en)
|
2018-05-11 |
2020-12-30 |
Crispr Therapeutics Ag |
Methods and compositions for treating cancer
|
|
US12157760B2
(en)
|
2018-05-23 |
2024-12-03 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
GB201808424D0
(en)
|
2018-05-23 |
2018-07-11 |
Lucite Int Uk Ltd |
Methods for producing BMA and MMA using genetically modified microorganisms
|
|
WO2019232542A2
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
GB201809273D0
(en)
|
2018-06-06 |
2018-07-25 |
Vib Vzw |
Novel mutant plant cinnamoyl-coa reductase proteins
|
|
CA3102975A1
(en)
|
2018-06-07 |
2019-12-12 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) |
Methods of regenerating and transforming cannabis
|
|
WO2019234754A1
(en)
|
2018-06-07 |
2019-12-12 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) |
Nucleic acid constructs and methods of using same
|
|
KR20210018437A
(ko)
|
2018-06-07 |
2021-02-17 |
더 브리검 앤드 우먼즈 하스피털, 인크. |
조혈 줄기 세포를 생산하기 위한 방법
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
EP3806619A1
(en)
|
2018-06-15 |
2021-04-21 |
Nunhems B.V. |
Seedless watermelon plants comprising modifications in an abc transporter gene
|
|
CA3103564A1
(en)
|
2018-06-15 |
2019-12-19 |
KWS SAAT SE & Co. KGaA |
Methods for enhancing genome engineering efficiency
|
|
WO2019238911A1
(en)
|
2018-06-15 |
2019-12-19 |
KWS SAAT SE & Co. KGaA |
Methods for improving genome engineering and regeneration in plant ii
|
|
AU2019285083B2
(en)
|
2018-06-15 |
2024-01-25 |
KWS SAAT SE & Co. KGaA |
Methods for improving genome engineering and regeneration in plant
|
|
WO2019246483A1
(en)
|
2018-06-21 |
2019-12-26 |
The Jackson Laboratory |
Genetically modified mouse models of alzheimer's disease
|
|
US11608506B2
(en)
|
2018-06-26 |
2023-03-21 |
Regents Of The University Of Minnesota |
Delivery of developmental regulators to plants for the induction of meristematic tissue with genetic alterations
|
|
US12264181B2
(en)
|
2018-06-27 |
2025-04-01 |
Altius Institute For Biomedical Sciences |
Nucleic acid binding domains and methods of use thereof
|
|
US20210324398A1
(en)
|
2018-06-29 |
2021-10-21 |
Pioneer Hi-Bred International, Inc. |
Edited nac genes in plants
|
|
CA3105331A1
(en)
|
2018-07-09 |
2020-01-16 |
Cellectis |
Canola with high oleic acid
|
|
US12247244B2
(en)
|
2018-07-31 |
2025-03-11 |
The University Of Tokyo |
Membrane protein activity measurement method
|
|
US11939593B2
(en)
|
2018-08-01 |
2024-03-26 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for improving embryo development
|
|
GB201812603D0
(en)
|
2018-08-02 |
2018-09-19 |
British American Tobacco Investments Ltd |
Method
|
|
SG11202100776SA
(en)
|
2018-08-07 |
2021-02-25 |
Modalis Therapeutics Corp |
Novel transcription activator
|
|
EP3607819A1
(en)
|
2018-08-10 |
2020-02-12 |
Vilmorin et Cie |
Resistance to xanthomonas campestris pv. campestris (xcc) in cauliflower
|
|
US11142740B2
(en)
|
2018-08-14 |
2021-10-12 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
|
US10532324B1
(en)
|
2018-08-14 |
2020-01-14 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
|
US10533152B1
(en)
|
2018-08-14 |
2020-01-14 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
|
WO2020041380A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
|
CA3109592A1
(en)
|
2018-08-23 |
2020-02-27 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
|
US20210189376A1
(en)
|
2018-08-29 |
2021-06-24 |
Amyris, Inc. |
Cells and methods for selection based assay
|
|
CN109706155B
(zh)
*
|
2018-08-30 |
2022-04-19 |
南京农业大学 |
pOsHEN1::OsSPL14基因表达盒及其构建方法和应用
|
|
AU2019363487A1
(en)
|
2018-08-30 |
2021-04-15 |
Inscripta, Inc. |
Improved detection of nuclease edited sequences in automated modules and instruments
|
|
CA3110289A1
(en)
|
2018-08-30 |
2020-03-05 |
The University Of North Carolina At Chapel Hill |
Feedback enabled synthetic genes, target seed match cassettes, and their uses
|
|
AU2019331009A1
(en)
|
2018-08-31 |
2021-03-18 |
Yale University |
Compositions and methods for enhancing donor oligonucleotide-based gene editing
|
|
WO2020047353A1
(en)
|
2018-08-31 |
2020-03-05 |
Yale University |
Compositions and methods for enhancing triplex and nuclease-based gene editing
|
|
EP3623379A1
(en)
|
2018-09-11 |
2020-03-18 |
KWS SAAT SE & Co. KGaA |
Beet necrotic yellow vein virus (bnyvv)-resistance modifying gene
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
JP7344300B2
(ja)
|
2018-09-18 |
2023-09-13 |
ブイエヌブイ ニューコ インク. |
Arcベースのカプシドおよびその使用
|
|
EP3853244A4
(en)
|
2018-09-18 |
2022-09-14 |
Sangamo Therapeutics, Inc. |
PROGRAMMED CELL DEATH 1 (PD1) SPECIFIC NUCLEASES
|
|
JP2022501036A
(ja)
*
|
2018-09-20 |
2022-01-06 |
サノフイSanofi |
イントロンベースの普遍的なクローニング方法および組成物
|
|
IL322436A
(en)
|
2018-09-21 |
2025-09-01 |
Acuitas Therapeutics Inc |
Systems and methods for producing lipid nanoparticles and liposomes
|
|
GB201815672D0
(en)
|
2018-09-26 |
2018-11-07 |
Innes John Centre |
Methods for altering starch granule size profile
|
|
EP3862430A4
(en)
|
2018-10-04 |
2022-06-15 |
Kaneka Corporation |
DNA CONSTRUCT FOR USE IN PLANT GENO EDITING
|
|
US20220411783A1
(en)
|
2018-10-12 |
2022-12-29 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
|
CA3116452A1
(en)
|
2018-10-15 |
2020-04-23 |
Fondazione Telethon |
Genome editing methods and constructs
|
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
|
BR112021007306A2
(pt)
|
2018-10-16 |
2021-07-27 |
Pioneer Hi-Bred International, Inc. |
mapeamento fino por edição genômica e identificação de gene causal
|
|
WO2020086475A1
(en)
|
2018-10-22 |
2020-04-30 |
Inscripta, Inc. |
Engineered enzymes
|
|
US11214781B2
(en)
|
2018-10-22 |
2022-01-04 |
Inscripta, Inc. |
Engineered enzyme
|
|
WO2020086627A1
(en)
|
2018-10-22 |
2020-04-30 |
University Of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas9 fusion protein
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
EP3873500A4
(en)
|
2018-10-31 |
2023-01-11 |
Mayo Foundation for Medical Education and Research |
METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
|
|
EP3873540A4
(en)
|
2018-10-31 |
2022-07-27 |
Mayo Foundation for Medical Education and Research |
METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
|
|
JP7499760B2
(ja)
|
2018-11-02 |
2024-06-14 |
アネクソン,インコーポレーテッド |
脳損傷を治療するための組成物及び方法
|
|
GB201817971D0
(en)
|
2018-11-02 |
2018-12-19 |
British American Tobacco Investments Ltd |
Method
|
|
EP3877421A1
(en)
|
2018-11-07 |
2021-09-15 |
CRISPR Therapeutics AG |
Anti-ptk7 immune cell cancer therapy
|
|
SG11202103832SA
(en)
|
2018-11-07 |
2021-05-28 |
Crispr Therapeutics Ag |
Anti-cd33 immune cell cancer therapy
|
|
US12304968B2
(en)
|
2018-11-07 |
2025-05-20 |
Crispr Therapeutics Ag |
T-cells expressing anti-LIV1 chimeric antigen receptor
|
|
US12402610B2
(en)
|
2018-11-09 |
2025-09-02 |
The Broad Institute, Inc. |
Methods and compositions for modulating innate lymphoid cell pathogenic effectors
|
|
US12165743B2
(en)
|
2018-11-09 |
2024-12-10 |
The Broad Institute, Inc. |
Compressed sensing for screening and tissue imaging
|
|
GB201818715D0
(en)
|
2018-11-16 |
2019-01-02 |
British American Tobacco Investments Ltd |
Method
|
|
EP3883611A4
(en)
|
2018-11-19 |
2023-02-22 |
Dana-Farber Cancer Institute, Inc. |
USE OF BIOMARKERS OF THE IRE1ALPHA-XBP1 SIGNALING PATHWAY TO MODULATE IMMUNE RESPONSE
|
|
IL283384B2
(en)
|
2018-11-27 |
2025-07-01 |
Khona Scient Inc |
Bidirectional multi-enzymatic scaffolds for cannabinoid biosynthesis
|
|
WO2020112195A1
(en)
|
2018-11-30 |
2020-06-04 |
Yale University |
Compositions, technologies and methods of using plerixafor to enhance gene editing
|
|
CA3121128A1
(en)
|
2018-12-02 |
2020-06-11 |
Fate Therapeutics, Inc. |
Immunotherapies using enhanced ipsc derived effector cells
|
|
WO2020118073A1
(en)
|
2018-12-05 |
2020-06-11 |
Vertex Pharmaceuticals Incorporated |
Gene-editing systems for editing a cystic fibrosis transmembrane regulator (cftr) gene
|
|
KR20200071198A
(ko)
|
2018-12-10 |
2020-06-19 |
네오이뮨텍, 인코퍼레이티드 |
Nrf2 발현 조절 기반 T 세포 항암면역치료법
|
|
GB201820109D0
(en)
|
2018-12-11 |
2019-01-23 |
Vib Vzw |
Plants with a lignin trait and udp-glycosyltransferase mutation
|
|
US12274205B2
(en)
|
2018-12-12 |
2025-04-15 |
Monsanto Technology Llc |
Delayed harvest of short stature corn plants
|
|
CN113544266A
(zh)
|
2018-12-17 |
2021-10-22 |
博德研究所 |
Crispr相关转座酶系统和其使用方法
|
|
JP7449291B2
(ja)
|
2018-12-20 |
2024-03-13 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ヌクレアーゼ媒介リピート伸長
|
|
US20220090047A1
(en)
|
2018-12-21 |
2022-03-24 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
WO2020146805A1
(en)
|
2019-01-11 |
2020-07-16 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
WO2020150144A1
(en)
|
2019-01-15 |
2020-07-23 |
Seminis Vegetable Seeds, Inc. |
Green bean plants with improved disease resistance
|
|
US12156877B1
(en)
|
2019-01-15 |
2024-12-03 |
The Regents Of The University Of California |
Methods of treating conditions related to a thiamine deficiency, a thiamine-dependent enzyme, or an associated cofactor
|
|
GB201900940D0
(en)
|
2019-01-23 |
2019-03-13 |
British American Tobacco Investments Ltd |
Method
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
EP3918080A1
(en)
|
2019-01-29 |
2021-12-08 |
The University Of Warwick |
Methods for enhancing genome engineering efficiency
|
|
JP7611151B2
(ja)
|
2019-02-06 |
2025-01-09 |
ヴィルモラン・エ・シエ |
細胞質雄性不稔を司る新たな遺伝子
|
|
WO2020172343A2
(en)
|
2019-02-19 |
2020-08-27 |
Massachusetts Institute Of Technology |
Methods for treating injuries
|
|
WO2020178193A1
(en)
|
2019-03-01 |
2020-09-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method of treatment of sarcoidosis
|
|
BR112021017655A2
(pt)
|
2019-03-07 |
2021-11-16 |
Univ Columbia |
Método e sistema de integração de dna guiada por rna usando transposons tipo tn7
|
|
EP3708651A1
(en)
|
2019-03-12 |
2020-09-16 |
KWS SAAT SE & Co. KGaA |
Improving plant regeneration
|
|
WO2020186237A1
(en)
|
2019-03-13 |
2020-09-17 |
The Broad Institute, Inc. |
Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof
|
|
AU2020240109A1
(en)
|
2019-03-19 |
2021-09-30 |
President And Fellows Of Harvard College |
Methods and compositions for editing nucleotide sequences
|
|
US11001831B2
(en)
|
2019-03-25 |
2021-05-11 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
|
EP3947691A4
(en)
|
2019-03-25 |
2022-12-14 |
Inscripta, Inc. |
SIMULTANEOUS MULTIPLEX GENOME EDITING IN A YEAST
|
|
IL316764A
(en)
|
2019-04-03 |
2025-01-01 |
Prec Biosciences Inc |
Genetically modified immune cells containing shRNA-targeted microRNA (shRNAmir)
|
|
KR20250148676A
(ko)
|
2019-04-03 |
2025-10-14 |
리제너론 파마슈티칼스 인코포레이티드 |
세이프 하버 좌위 내로의 항체 코딩 서열의 삽입을 위한 방법 및 조성물
|
|
IL286905B2
(en)
|
2019-04-04 |
2024-06-01 |
Regeneron Pharma |
Non-human animals containing the human coagulation factor 12 locus
|
|
IL286917B
(en)
|
2019-04-04 |
2022-09-01 |
Regeneron Pharma |
Methods for scarless introduction of targeted modifications into targeting vectors
|
|
JP7426120B2
(ja)
|
2019-04-05 |
2024-02-01 |
国立大学法人大阪大学 |
ノックイン細胞の作製方法
|
|
CA3136265A1
(en)
|
2019-04-05 |
2020-10-08 |
Precision Biosciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
EP3969607A1
(en)
|
2019-05-13 |
2022-03-23 |
KWS SAAT SE & Co. KGaA |
Drought tolerance in corn
|
|
GB201906768D0
(en)
|
2019-05-14 |
2019-06-26 |
British American Tobacco Investments Ltd |
Method
|
|
PH12021553009A1
(en)
|
2019-05-23 |
2022-11-07 |
Univ Nanjing Agricultural |
Methods for improving rice grain yield
|
|
AR118995A1
(es)
|
2019-05-25 |
2021-11-17 |
Kws Saat Se & Co Kgaa |
Mejorador de la inducción de haploides
|
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
AU2020284555A1
(en)
|
2019-05-28 |
2021-12-23 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuated anti-viral transfer vector immune response
|
|
US20220243178A1
(en)
|
2019-05-31 |
2022-08-04 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
|
KR20220016869A
(ko)
|
2019-06-04 |
2022-02-10 |
리제너론 파마슈티칼스 인코포레이티드 |
베타-슬립 돌연변이를 갖는 인간화 ttr 좌위를 포함하는 비-인간 동물 및 사용 방법
|
|
WO2020244759A1
(en)
|
2019-06-05 |
2020-12-10 |
Klemm & Sohn Gmbh & Co. Kg |
New plants having a white foliage phenotype
|
|
US10837021B1
(en)
|
2019-06-06 |
2020-11-17 |
Inscripta, Inc. |
Curing for recursive nucleic acid-guided cell editing
|
|
BR112021022722A2
(pt)
|
2019-06-07 |
2022-01-04 |
Regeneron Pharma |
Animal não humano, célula de animal não humana, genoma de animal não humano, gene de albumina animal não humana humanizada, vetor de alvejamento, método de avaliação da atividade de um reagente, e, método de otimização da atividade de um reagente
|
|
JP2022536364A
(ja)
|
2019-06-13 |
2022-08-15 |
ザ ジェネラル ホスピタル コーポレイション |
操作されたヒト内在性ウイルス様粒子および細胞への送達のためのその使用方法
|
|
KR20220024053A
(ko)
|
2019-06-14 |
2022-03-03 |
리제너론 파마슈티칼스 인코포레이티드 |
타우병증의 모델
|
|
EP3987024A4
(en)
|
2019-06-20 |
2023-11-01 |
University Of Massachusetts |
COMPOSITIONS AND METHODS FOR ENHANCED GENOMIC EDITING
|
|
WO2020254850A1
(en)
|
2019-06-21 |
2020-12-24 |
Vilmorin & Cie |
Improvement of quality and permanence of green color of peppers at maturity and over-maturity
|
|
EP3986909A4
(en)
|
2019-06-21 |
2023-08-02 |
Inscripta, Inc. |
Genome-wide rationally-designed mutations leading to enhanced lysine production in e. coli
|
|
US10927385B2
(en)
|
2019-06-25 |
2021-02-23 |
Inscripta, Inc. |
Increased nucleic-acid guided cell editing in yeast
|
|
PH12021553254A1
(en)
|
2019-06-27 |
2022-09-19 |
Crispr Therapeutics Ag |
Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer
|
|
EP3757219A1
(en)
|
2019-06-28 |
2020-12-30 |
KWS SAAT SE & Co. KGaA |
Enhanced plant regeneration and transformation by using grf1 booster gene
|
|
EP3997059A4
(en)
|
2019-07-03 |
2023-12-13 |
Factor Bioscience Inc. |
CATIONIC LIPIDS AND THEIR USES
|
|
GB201909563D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
|
GB201909562D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
|
CA3145863A1
(en)
|
2019-07-05 |
2021-01-14 |
Limagrain Europe |
Method for increasing yield in plants
|
|
WO2021007284A2
(en)
|
2019-07-11 |
2021-01-14 |
The Regents Of The University Of California |
Methods for improved regeneration of transgenic plants using growth-regulating factor (grf), grf-interacting factor (gif), or chimeric grf-gif genes and proteins
|
|
AU2020318781A1
(en)
|
2019-07-23 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immune cells defective for SUV39H1
|
|
FR3099178A1
(fr)
|
2019-07-24 |
2021-01-29 |
Soltis |
Tournesol à teneur élevée en acide oléique et procédé d’obtention
|
|
EP4004216A1
(en)
|
2019-07-25 |
2022-06-01 |
Precision BioSciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
US10501404B1
(en)
|
2019-07-30 |
2019-12-10 |
Factor Bioscience Inc. |
Cationic lipids and transfection methods
|
|
EP4002993A4
(en)
|
2019-07-30 |
2024-01-10 |
Pairwise Plants Services, Inc. |
MORPHOGENIC REGULATORS AND METHODS OF USE
|
|
WO2021019272A1
(en)
|
2019-07-31 |
2021-02-04 |
Vilmorin & Cie |
Tolerance to tolcndv in cucumber
|
|
EP3772542A1
(en)
|
2019-08-07 |
2021-02-10 |
KWS SAAT SE & Co. KGaA |
Modifying genetic variation in crops by modulating the pachytene checkpoint protein 2
|
|
WO2021035054A1
(en)
|
2019-08-20 |
2021-02-25 |
Precision Biosciences, Inc. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
US20220298501A1
(en)
|
2019-08-30 |
2022-09-22 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
US12485180B2
(en)
|
2019-08-30 |
2025-12-02 |
Yale University |
Compositions and methods for delivery of nucleic acids to cells
|
|
US12344656B2
(en)
|
2019-09-06 |
2025-07-01 |
Crispr Therapeutics Ag |
Genetically engineered T cells having improved persistence in culture
|
|
CA3147641A1
(en)
|
2019-09-23 |
2021-04-01 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein b (apob) gene expression
|
|
CN114729376A
(zh)
|
2019-09-23 |
2022-07-08 |
欧米茄治疗公司 |
用于调节肝细胞核因子4α(HNF4α)基因表达的组合物和方法
|
|
SG10202008262UA
(en)
|
2019-09-26 |
2021-04-29 |
Seminis Vegetable Seeds Inc |
Lettuce plants having resistance to nasonovia ribisnigri biotype nr:1
|
|
GB201914137D0
(en)
|
2019-10-01 |
2019-11-13 |
Univ Leeds Innovations Ltd |
Modified Plants
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
EP3808170A1
(en)
|
2019-10-17 |
2021-04-21 |
Bejo Zaden B.V. |
Lactuca sativa resistance to bremia lactucae
|
|
WO2021074367A1
(en)
|
2019-10-17 |
2021-04-22 |
KWS SAAT SE & Co. KGaA |
Enhanced disease resistance of crops by downregulation of repressor genes
|
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
CN121109454A
(zh)
|
2019-11-06 |
2025-12-12 |
青岛清原化合物有限公司 |
在生物体内创制新基因的方法及应用
|
|
EP4054651A1
(en)
|
2019-11-08 |
2022-09-14 |
Regeneron Pharmaceuticals, Inc. |
Crispr and aav strategies for x-linked juvenile retinoschisis therapy
|
|
WO2021093943A1
(en)
|
2019-11-12 |
2021-05-20 |
KWS SAAT SE & Co. KGaA |
Gene for resistance to a pathogen of the genus heterodera
|
|
JP7448120B2
(ja)
|
2019-11-14 |
2024-03-12 |
国立研究開発法人農業・食品産業技術総合研究機構 |
プラズマを用いてゲノム編集酵素を植物細胞内に導入する方法
|
|
US20230250415A1
(en)
|
2019-11-14 |
2023-08-10 |
Hiroshima University |
Method for introducing antigen-specific receptor gene into t cell genome using circular dna
|
|
WO2021094805A1
(en)
|
2019-11-14 |
2021-05-20 |
Vilmorin & Cie |
Resistance to acidovorax valerianellae in corn salad
|
|
US11203762B2
(en)
|
2019-11-19 |
2021-12-21 |
Inscripta, Inc. |
Methods for increasing observed editing in bacteria
|
|
WO2021108363A1
(en)
|
2019-11-25 |
2021-06-03 |
Regeneron Pharmaceuticals, Inc. |
Crispr/cas-mediated upregulation of humanized ttr allele
|
|
AU2020391435A1
(en)
|
2019-11-27 |
2022-06-23 |
Cibus Europe B.V. |
Tal-effector nucleases for gene editing
|
|
WO2021113543A1
(en)
|
2019-12-06 |
2021-06-10 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy, using lymphodepletion regimens and cd19, cd20 or bcma allogeneic car t cells
|
|
KR20250033331A
(ko)
|
2019-12-10 |
2025-03-07 |
인스크립타 인코포레이티드 |
신규 mad 뉴클레아제
|
|
US10704033B1
(en)
|
2019-12-13 |
2020-07-07 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
US20230000063A1
(en)
|
2019-12-13 |
2023-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
System for detecting extracellular purinergic receptor ligand, and non-human animal having the system introduced thereinto
|
|
EP3835309A1
(en)
|
2019-12-13 |
2021-06-16 |
KWS SAAT SE & Co. KGaA |
Method for increasing cold or frost tolerance in a plant
|
|
CN113061626B
(zh)
*
|
2019-12-16 |
2024-01-19 |
中国科学院脑科学与智能技术卓越创新中心 |
一种组织特异性敲除斑马鱼基因的方法及应用
|
|
EP4069851A4
(en)
|
2019-12-18 |
2023-11-22 |
Inscripta, Inc. |
Cascade/dcas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
|
|
GB201918902D0
(en)
|
2019-12-19 |
2020-02-05 |
Genome Res Ltd |
Cell differentiation
|
|
US10689669B1
(en)
|
2020-01-11 |
2020-06-23 |
Inscripta, Inc. |
Automated multi-module cell processing methods, instruments, and systems
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
KR20220133257A
(ko)
|
2020-01-27 |
2022-10-04 |
인스크립타 인코포레이티드 |
전기천공 모듈 및 기구
|
|
CN115135144A
(zh)
|
2020-01-31 |
2022-09-30 |
卡里克特公司 |
大豆中饱和脂肪的增加
|
|
EP4100525A1
(en)
|
2020-02-05 |
2022-12-14 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods of treatment of cancer disease by targeting an epigenetic factor
|
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
|
US20230091338A1
(en)
|
2020-02-24 |
2023-03-23 |
Pioneer Hi-Bred International, Inc. |
Intra-genomic homologous recombination
|
|
US20230107598A1
(en)
|
2020-02-28 |
2023-04-06 |
Pioneer Hi-Bred International, Inc. |
Sorghum doubled haploid production system
|
|
CN115605600A
(zh)
|
2020-02-28 |
2023-01-13 |
科沃施种子欧洲股份两合公司(De) |
未成熟花序分生组织编辑
|
|
WO2021178556A1
(en)
|
2020-03-04 |
2021-09-10 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for sensitization of tumor cells to immune therapy
|
|
WO2021183636A1
(en)
|
2020-03-10 |
2021-09-16 |
Calyxt, Inc. |
Transformation and regeneration of cannabaceae
|
|
JP2023517326A
(ja)
|
2020-03-11 |
2023-04-25 |
オメガ セラピューティクス, インコーポレイテッド |
フォークヘッドボックスp3(foxp3)遺伝子発現をモジュレートするための組成物および方法
|
|
EP4129050A4
(en)
|
2020-03-26 |
2024-05-08 |
National Agriculture And Food Research Organization |
METHOD FOR PRODUCING A TEMPERATURE SENSITIVE MALE STERILE PLANT
|
|
EP4127139A1
(en)
|
2020-03-27 |
2023-02-08 |
Mendus B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
US20230263121A1
(en)
|
2020-03-31 |
2023-08-24 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
|
WO2021202648A1
(en)
|
2020-03-31 |
2021-10-07 |
Calyxt, Inc. |
Agrobacterium-mediated infiltration of cannabaceae
|
|
BR112022020546A2
(pt)
|
2020-04-09 |
2022-12-20 |
Reynolds Tobacco Co R |
Método
|
|
NL2025344B1
(en)
|
2020-04-14 |
2021-10-26 |
Academisch Ziekenhuis Leiden |
Methods for induction of endogenous tandem duplication events
|
|
CN115915927A
(zh)
|
2020-04-14 |
2023-04-04 |
莱顿大学医学中心附属莱顿教学医院 |
用于诱导内源性串联复制事件的方法
|
|
US20210332388A1
(en)
|
2020-04-24 |
2021-10-28 |
Inscripta, Inc. |
Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
|
|
WO2021224633A1
(en)
|
2020-05-06 |
2021-11-11 |
Orchard Therapeutics (Europe) Limited |
Treatment for neurodegenerative diseases
|
|
WO2021224416A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
|
CA3177093A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
|
BR112022022603A2
(pt)
|
2020-05-08 |
2023-01-17 |
Broad Inst Inc |
Métodos e composições para edição simultânea de ambas as fitas de sequência alvo de nucleotídeos de fita dupla
|
|
US20230183664A1
(en)
|
2020-05-11 |
2023-06-15 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
|
US11787841B2
(en)
|
2020-05-19 |
2023-10-17 |
Inscripta, Inc. |
Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
|
|
JP2023527446A
(ja)
|
2020-05-29 |
2023-06-28 |
カー・ヴェー・エス ザート エス・エー ウント コー. カー・ゲー・アー・アー |
植物単数体の誘導
|
|
WO2021245435A1
(en)
|
2020-06-03 |
2021-12-09 |
Vilmorin & Cie |
Melon plants resistant to scab disease, aphids and powdery mildew
|
|
WO2021248052A1
(en)
|
2020-06-05 |
2021-12-09 |
The Broad Institute, Inc. |
Compositions and methods for treating neoplasia
|
|
IL298618A
(en)
|
2020-06-05 |
2023-01-01 |
Vilmorin & Cie |
Tobrfv resistance of Solanum lycopersicum plants
|
|
EP4168538A4
(en)
|
2020-06-19 |
2024-03-20 |
Fate Therapeutics, Inc. |
COMBINATION OF IPSC-DERIVED EFFECTOR CELL TYPES FOR IMMUNOTHERAPY USE
|
|
US20230305023A1
(en)
|
2020-06-25 |
2023-09-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment and diagnostic of pathological conditions associated with intense stress
|
|
KR20230033647A
(ko)
|
2020-06-30 |
2023-03-08 |
멘두스 비.브이. |
난소암 백신에서 백혈병 유래 세포의 용도
|
|
BR112022026128A2
(pt)
|
2020-07-14 |
2023-01-24 |
Kws Saat Se & Co Kgaa |
Métodos para identificar e selecionar plantas de milho com resistência à mangra da folha do milho do norte
|
|
AU2021204717A1
(en)
|
2020-07-15 |
2022-02-03 |
Seminis Vegetable Seeds, Inc. |
Green Bean Plants with Improved Disease Resistance
|
|
BR112023000327A2
(pt)
|
2020-07-16 |
2023-01-31 |
Acuitas Therapeutics Inc |
Lipídeos catiônicos para o uso em nanopartículas lipídicas
|
|
WO2022020800A2
(en)
|
2020-07-24 |
2022-01-27 |
The General Hospital Corporation |
Enhanced virus-like particles and methods of use thereof for delivery to cells
|
|
CA3190266A1
(en)
|
2020-07-30 |
2022-02-03 |
Institut Curie |
Immune cells defective for socs1
|
|
EP4192875A1
(en)
|
2020-08-10 |
2023-06-14 |
Precision BioSciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
EP4501951A3
(en)
|
2020-08-25 |
2025-04-30 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
KR20230079367A
(ko)
|
2020-08-31 |
2023-06-07 |
예일 유니버시티 |
핵산을 세포에 전달하기 위한 조성물 및 방법
|
|
CN116134141A
(zh)
|
2020-09-04 |
2023-05-16 |
国立大学法人神户大学 |
包含小型化胞苷脱氨酶的双链dna修饰用复合体
|
|
WO2022049273A1
(en)
|
2020-09-07 |
2022-03-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment of inflammatory bowel diseases
|
|
US11299731B1
(en)
|
2020-09-15 |
2022-04-12 |
Inscripta, Inc. |
CRISPR editing to embed nucleic acid landing pads into genomes of live cells
|
|
EP3971295A1
(en)
|
2020-09-16 |
2022-03-23 |
FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. |
Methods for the production of genome edited plants
|
|
EP4176048B1
(en)
|
2020-09-23 |
2024-09-11 |
CRISPR Therapeutics AG |
Genetically engineered t cells with regnase-1 and/or tgfbrii disruption have improved functionality and persistence
|
|
CA3193099A1
(en)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Prime editing guide rnas, compositions thereof, and methods of using the same
|
|
IL301846A
(en)
|
2020-10-02 |
2023-06-01 |
Vilmorin & Cie |
A hotel with an extended shelf life
|
|
US20230365995A1
(en)
|
2020-10-07 |
2023-11-16 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
|
CR20230175A
(es)
|
2020-10-23 |
2023-07-26 |
Elo Life Systems Inc |
Métodos para producir plantas de vainilla con mejor sabor y producción agronómica
|
|
WO2022097663A1
(ja)
|
2020-11-06 |
2022-05-12 |
エディットフォース株式会社 |
FokIヌクレアーゼドメインの変異体
|
|
EP4240874A1
(en)
|
2020-11-06 |
2023-09-13 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for diagnosis and treating polycystic ovary syndrome (pcos)
|
|
US11512297B2
(en)
|
2020-11-09 |
2022-11-29 |
Inscripta, Inc. |
Affinity tag for recombination protein recruitment
|
|
WO2022103799A1
(en)
|
2020-11-10 |
2022-05-19 |
Industrial Microbes, Inc. |
Microorganisms capable of producing poly(hiba) from feedstock
|
|
EP4244384A4
(en)
|
2020-11-10 |
2024-10-23 |
Mayo Foundation for Medical Education and Research |
METHODS AND MATERIALS FOR TREATING HEART FAILURE
|
|
US20220211018A1
(en)
|
2020-11-20 |
2022-07-07 |
Revivicor, Inc. |
Multi-transgenic pigs with growth hormone receptor knockout for xenotransplantation
|
|
WO2022112469A1
(en)
|
2020-11-27 |
2022-06-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosis and monitoring of toxic epidermal necrolysis
|
|
WO2022112596A1
(en)
|
2020-11-30 |
2022-06-02 |
Cellectis Sa |
Use of aminoquinoline compounds for higher gene integration
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
MA60481B1
(fr)
|
2020-12-03 |
2025-04-30 |
Vilmorin & Cie |
Plants de tomate résistants au tobrfv, au tmv, au tomv et au tommv, et gènes de résistance correspondants
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
EP4019638A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
|
EP4019639A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
|
WO2022137181A1
(en)
|
2020-12-23 |
2022-06-30 |
Crispr Therapeutics Ag |
Co-use of lenalidomide with car-t cells
|
|
JP2024501022A
(ja)
|
2020-12-28 |
2024-01-10 |
アークトゥルス セラピューティクス, インコーポレイテッド |
Hbvを標的とする転写活性化因子様エフェクターヌクレアーゼ(talen)
|
|
WO2022146497A1
(en)
|
2021-01-04 |
2022-07-07 |
Inscripta, Inc. |
Mad nucleases
|
|
WO2022150269A1
(en)
|
2021-01-07 |
2022-07-14 |
Inscripta, Inc. |
Mad nucleases
|
|
CA3203876A1
(en)
|
2021-01-11 |
2022-07-14 |
David R. Liu |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|
|
US20240318159A1
(en)
|
2021-01-12 |
2024-09-26 |
Mitolab Inc. |
Context-dependent, double-stranded dna-specific deaminases and uses thereof
|
|
EP4277933A4
(en)
|
2021-01-14 |
2024-12-11 |
Senti Biosciences, Inc. |
SECRETABLE PAYLOAD REGULATION
|
|
CA3203705A1
(en)
|
2021-01-22 |
2022-07-28 |
Erik Hans MANTING |
Methods of tumor vaccination
|
|
EP4284823A1
(en)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
US11884924B2
(en)
|
2021-02-16 |
2024-01-30 |
Inscripta, Inc. |
Dual strand nucleic acid-guided nickase editing
|
|
US20220288122A1
(en)
|
2021-03-09 |
2022-09-15 |
Crispr Therapeutics Ag |
Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity
|
|
JP2024510989A
(ja)
|
2021-03-12 |
2024-03-12 |
メンドゥス・ベスローテン・フェンノートシャップ |
ワクチン接種方法及びcd47遮断薬の使用
|
|
WO2022198107A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalain in cannabaceae plant parts
|
|
WO2022198085A2
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Plant cell matrices and methods thereof
|
|
WO2022198106A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalains using plant cell matrices
|
|
WO2022198094A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin in cannabaceae plant parts
|
|
WO2022198093A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin using plant cell matrices
|
|
WO2022208489A1
(en)
|
2021-04-02 |
2022-10-06 |
Vilmorin & Cie |
Semi-determinate or determinate growth habit trait in cucurbita
|
|
AU2022253223A1
(en)
|
2021-04-07 |
2023-09-28 |
Century Therapeutics, Inc. |
Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof
|
|
MX2023011927A
(es)
|
2021-04-07 |
2023-10-23 |
Century Therapeutics Inc |
Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas.
|
|
CA3214473A1
(en)
|
2021-04-07 |
2022-10-13 |
Century Therapeutics, Inc. |
Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells
|
|
WO2022218998A1
(en)
|
2021-04-13 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for treating hepatitis b and d virus infection
|
|
WO2022226316A1
(en)
|
2021-04-22 |
2022-10-27 |
Precision Biosciences, Inc. |
Compositions and methods for generating male sterile plants
|
|
MX2023012511A
(es)
|
2021-04-23 |
2024-01-08 |
Univ Rochester |
Edición del genóma por inserción no homóloga de adn dirigida utilizando una proteína de fusión retroviral de integrasa-cas y métodos de tratamiento.
|
|
KR20240007179A
(ko)
|
2021-04-30 |
2024-01-16 |
셀렉티스 에스.에이. |
고형 종양 암 면역 요법을 위한 새로운 항-muc1 car 및 유전자 편집된 면역세포
|
|
US20240247285A1
(en)
|
2021-05-10 |
2024-07-25 |
Sqz Biotechnologies Company |
Methods for delivering genome editing molecules to the nucleus or cytosol of a cell and uses thereof
|
|
WO2022251644A1
(en)
|
2021-05-28 |
2022-12-01 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
|
EP4347826A1
(en)
|
2021-06-02 |
2024-04-10 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
|
US20230045095A1
(en)
|
2021-06-23 |
2023-02-09 |
Massachusetts Institute Of Technology |
Compositions, Methods and Systems for the Delivery of Gene Editing Material to Cells
|
|
CN118339297A
(zh)
|
2021-07-07 |
2024-07-12 |
希博斯欧洲有限公司 |
与内含肽融合的转录激活因子样效应物
|
|
EP4367242A2
(en)
|
2021-07-07 |
2024-05-15 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
AR126622A1
(es)
|
2021-07-30 |
2023-10-25 |
Kws Saat Se & Co Kgaa |
Plantas con digestibilidad mejorada y haplotipos marcadores
|
|
EP4380353A1
(en)
|
2021-08-06 |
2024-06-12 |
Vilmorin & Cie |
Resistance to leveillula taurica in pepper
|
|
JP7125727B1
(ja)
|
2021-09-07 |
2022-08-25 |
国立大学法人千葉大学 |
核酸配列改変用組成物および核酸配列の標的部位を改変する方法
|
|
WO2023042079A1
(en)
|
2021-09-14 |
2023-03-23 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having a disrupted cd83 gene
|
|
IL311512A
(en)
|
2021-09-17 |
2024-05-01 |
Cibus Europe Bv |
Transforming cannabaceae cells
|
|
US20230255185A1
(en)
|
2021-09-20 |
2023-08-17 |
Revivicor, Inc. |
Multitransgenic pigs comprising ten genetic modifications for xenotransplantation
|
|
EP4409007A4
(en)
|
2021-09-27 |
2025-10-08 |
Monsanto Technology Llc |
COMPOSITIONS AND METHODS FOR TRANSFORMING EXPLANTS OF EXCISED EMBRYO FROM MONOCOTYLEDONOUS SEEDS
|
|
GB202113933D0
(en)
|
2021-09-29 |
2021-11-10 |
Genome Res Ltd |
Methods for gene editing
|
|
WO2023064367A1
(en)
|
2021-10-12 |
2023-04-20 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating anti-viral transfer vector igm responses
|
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
|
EP4416292A2
(en)
|
2021-10-14 |
2024-08-21 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
|
KR20240082391A
(ko)
|
2021-10-14 |
2024-06-10 |
론자 세일즈 아게 |
세포외 소포 생산을 위한 변형된 생산자 세포
|
|
WO2023070003A1
(en)
|
2021-10-19 |
2023-04-27 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
|
US20230226116A1
(en)
|
2021-10-20 |
2023-07-20 |
University Of Rochester |
Method for rejuvenating glial progenitor cells and rejuvenated glial progenitor cells per se
|
|
WO2023070043A1
(en)
|
2021-10-20 |
2023-04-27 |
Yale University |
Compositions and methods for targeted editing and evolution of repetitive genetic elements
|
|
EP4419685A1
(en)
|
2021-10-20 |
2024-08-28 |
University of Rochester |
Compositions and methods for treating myelin deficiency by rejuvenating glial progenitor cells
|
|
AU2022371442A1
(en)
|
2021-10-21 |
2024-04-18 |
Vertex Pharmaceuticals Incorporated |
Hypoimmune cells
|
|
IL312506A
(en)
|
2021-11-08 |
2024-07-01 |
Progentos Therapeutics Inc |
Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
|
|
US11753677B2
(en)
|
2021-11-10 |
2023-09-12 |
Encodia, Inc. |
Methods for barcoding macromolecules in individual cells
|
|
US20250009800A1
(en)
|
2021-11-16 |
2025-01-09 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
KR20240110844A
(ko)
|
2021-11-23 |
2024-07-16 |
셀렉티스 에스.에이. |
개선된 온-타겟/오프-타겟 활성 비율을 갖는 신규 tale 단백질 스캐폴드
|
|
WO2023093862A1
(en)
|
2021-11-26 |
2023-06-01 |
Epigenic Therapeutics Inc. |
Method of modulating pcsk9 and uses thereof
|
|
WO2023102393A1
(en)
|
2021-11-30 |
2023-06-08 |
Pioneer Hi-Bred International, Inc. |
High efficiency large scale chromosomal genome manipulation
|
|
GB202117314D0
(en)
|
2021-11-30 |
2022-01-12 |
Clarke David John |
Cyclic nucleic acid fragmentation
|
|
JP2024544012A
(ja)
|
2021-12-03 |
2024-11-26 |
ザ ブロード インスティテュート,インコーポレーテッド |
核酸プログラマブル融合タンパク質を送達するためのセルフアセンブルウイルス様粒子ならびにその作製方法および使用方法
|
|
EP4441074A2
(en)
|
2021-12-03 |
2024-10-09 |
The Broad Institute, Inc. |
Compositions and methods for efficient in vivo delivery
|
|
US20230193310A1
(en)
|
2021-12-10 |
2023-06-22 |
Seminis Vegetabe Seeds, Inc. |
Lettuce plants having resistance to downy mildew
|
|
GB202118058D0
(en)
|
2021-12-14 |
2022-01-26 |
Univ Warwick |
Methods to increase yields in crops
|
|
WO2023111913A1
(en)
|
2021-12-15 |
2023-06-22 |
Crispr Therapeutics Ag |
Engineered anti-liv1 cell with regnase-1 and/or tgfbrii disruption
|
|
US20250340931A1
(en)
|
2021-12-15 |
2025-11-06 |
Nanjing GenScript Biotech Co., Ltd. |
Method for detecting integration site
|
|
KR20240123832A
(ko)
|
2021-12-16 |
2024-08-14 |
아퀴타스 테라퓨틱스 인크. |
지질 나노입자 제형에 사용하기 위한 지질
|
|
KR20240122535A
(ko)
*
|
2021-12-17 |
2024-08-12 |
제니퍼 엠. 쉐론 |
바이러스의 재조합에 내성이 있는 반복 서열을 암호화하는 핵산 서열
|
|
EP4452304A1
(en)
|
2021-12-22 |
2024-10-30 |
CRISPR Therapeutics AG |
Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof
|
|
EP4456910A1
(en)
|
2021-12-28 |
2024-11-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
|
JP2025501214A
(ja)
|
2021-12-29 |
2025-01-17 |
センチュリー セラピューティクス,インコーポレイテッド |
抗cd19/抗cd22キメラ抗原受容体を有する遺伝子操作細胞、およびその使用
|
|
AU2022424002A1
(en)
|
2021-12-29 |
2024-06-13 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
|
EP4472648A1
(en)
|
2022-02-01 |
2024-12-11 |
University of Rochester |
Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods
|
|
EP4472737A1
(en)
|
2022-02-01 |
2024-12-11 |
University of Rochester |
Gpr17 promoter-based targeting and transduction of glial progenitor cells
|
|
MX2024009604A
(es)
|
2022-02-03 |
2024-08-14 |
Nicoventures Trading Ltd |
Metodo.
|
|
WO2023148478A1
(en)
|
2022-02-03 |
2023-08-10 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
|
US20250137005A1
(en)
|
2022-02-04 |
2025-05-01 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
|
WO2023158732A1
(en)
|
2022-02-16 |
2023-08-24 |
Dana-Farber Cancer Institute, Inc. |
Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereof
|
|
US12037616B2
(en)
|
2022-03-01 |
2024-07-16 |
Crispr Therapeutics Ag |
Methods and compositions for treating angiopoietin-like 3 (ANGPTL3) related conditions
|
|
US20230357437A1
(en)
|
2022-03-09 |
2023-11-09 |
Selecta Biosciences, Inc. |
Immunosuppressants in combination with anti-igm agents and related dosing
|
|
WO2023180904A1
(en)
|
2022-03-21 |
2023-09-28 |
Crispr Therapeutics Ag |
Methods and compositions for treating lipoprotein-related diseases
|
|
US20230331841A1
(en)
|
2022-03-23 |
2023-10-19 |
Crispr Therapeutics Ag |
Anti-cd83 car-t cells with regnase-1 and/or tgfbrii disruption
|
|
TW202400778A
(zh)
|
2022-03-23 |
2024-01-01 |
瑞士商Crispr治療公司 |
具有多重基因編輯之抗cd19 car—t細胞及其治療用途
|
|
EP4256950A1
(en)
|
2022-04-06 |
2023-10-11 |
Vilmorin et Cie |
Tolerance to cgmmv in cucumber
|
|
GB202205148D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
|
GB202205149D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
|
EP4504799A1
(en)
|
2022-04-08 |
2025-02-12 |
Fate Therapeutics, Inc. |
Chimeric antigen receptor for tumor targeting
|
|
IL316101A
(en)
|
2022-04-08 |
2024-12-01 |
Fate Therapeutics Inc |
Skeletal cells refer to solid tumors and their use
|
|
GB202205561D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
|
GB202205562D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
|
GB202206109D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
|
GB202206107D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
|
JP2025515030A
(ja)
|
2022-05-02 |
2025-05-13 |
フォンダジオン テレソン イーティーエス |
遺伝子編集用の相同性非依存性標的組込み
|
|
JP2025516527A
(ja)
|
2022-05-09 |
2025-05-30 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
インビボ抗体産生のためのベクター及び方法
|
|
WO2023225572A2
(en)
|
2022-05-17 |
2023-11-23 |
Nvelop Therapeutics, Inc. |
Compositions and methods for efficient in vivo delivery
|
|
AU2023273885A1
(en)
|
2022-05-19 |
2024-12-05 |
Lyell Immunopharma, Inc. |
Polynucleotides targeting nr4a3 and uses thereof
|
|
EP4278891A1
(en)
|
2022-05-20 |
2023-11-22 |
KWS SAAT SE & Co. KGaA |
Clubroot resistance and markers in brassica
|
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
|
GB202207774D0
(en)
|
2022-05-26 |
2022-07-13 |
Cambridge Entpr Ltd |
Modified plants
|
|
WO2023240169A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof
|
|
CN119630695A
(zh)
|
2022-06-08 |
2025-03-14 |
世纪治疗股份有限公司 |
表达cd16变体和nkg2d的遗传工程化细胞及其用途
|
|
WO2023240212A2
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
|
|
WO2023242827A2
(en)
|
2022-06-17 |
2023-12-21 |
Crispr Therapeutics Ag |
LIPID NANOPARTICLES (LNPs)-BASED OCULAR DELIVERY
|
|
WO2023248147A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Methods and compositions for in vivo editing of stem cells
|
|
WO2023248145A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Compositions and methods for treating human immunodeficiency virus
|
|
WO2023250288A2
(en)
|
2022-06-21 |
2023-12-28 |
Seminis Vegetable Seeds, Inc. |
Novel qtls conferring resistance to cucumber mosaic virus
|
|
EP4547718A1
(en)
|
2022-06-29 |
2025-05-07 |
CRISPR Therapeutics AG |
Chimeric antigen receptor targeting gpc-3 and immune cells expressing such for therapeutic uses
|
|
GB2621813A
(en)
|
2022-06-30 |
2024-02-28 |
Univ Newcastle |
Preventing disease recurrence in Mitochondrial replacement therapy
|
|
WO2024020360A1
(en)
|
2022-07-18 |
2024-01-25 |
Pairwise Plants Services, Inc. |
Mustard green plants named 'pwrg-1', 'pwrg-2,' and 'pwsgc'
|
|
EP4558173A1
(en)
|
2022-07-22 |
2025-05-28 |
The Johns Hopkins University |
Dendrimer-enabled targeted intracellular crispr/cas system delivery and gene editing
|
|
WO2024023802A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene
|
|
WO2024023801A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene
|
|
KR20250054842A
(ko)
|
2022-07-29 |
2025-04-23 |
리제너론 파마슈티칼스 인코포레이티드 |
뇌 및 근육으로의 트랜스페린 수용체(tfr)-매개 전달을 위한 조성물 및 방법
|
|
WO2024023804A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene
|
|
LU502613B1
(en)
|
2022-08-01 |
2024-02-01 |
Plant Bioscience Ltd |
Methods of altering the starch granule profile in plants
|
|
CN119562964A
(zh)
|
2022-08-05 |
2025-03-04 |
瑞泽恩制药公司 |
tdp-43的抗聚集变体
|
|
AU2023329149A1
(en)
|
2022-08-26 |
2025-02-20 |
KWS SAAT SE & Co. KGaA |
Use of paired genes in hybrid breeding
|
|
WO2024062388A2
(en)
|
2022-09-20 |
2024-03-28 |
Crispr Therapeutics Ag |
Genetically engineered immune cells expressing chimeric antigen receptor targeting cd20
|
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
|
WO2024064958A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
|
WO2024064952A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells overexpressing c-jun
|
|
GB202214410D0
(en)
|
2022-09-30 |
2022-11-16 |
Ivy Farm Tech Limited |
genetically modified cells
|
|
WO2024077174A1
(en)
|
2022-10-05 |
2024-04-11 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
|
WO2024079157A1
(en)
|
2022-10-11 |
2024-04-18 |
KWS SAAT SE & Co. KGaA |
Virus and insect resistance and markers in barley
|
|
WO2024081736A2
(en)
|
2022-10-11 |
2024-04-18 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
|
WO2024084025A1
(en)
|
2022-10-21 |
2024-04-25 |
Keygene N.V. |
Rna transfection in plant cells with modified rna
|
|
WO2024102838A1
(en)
|
2022-11-09 |
2024-05-16 |
Century Therapeutics, Inc. |
Engineered interleukin-7 receptors and uses thereof
|
|
JP2025537284A
(ja)
|
2022-11-10 |
2025-11-14 |
センチュリー セラピューティクス,インコーポレイテッド |
抗ネクチン4キメラ抗原受容体を有する遺伝子操作細胞、およびその使用
|
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
|
WO2024108092A1
(en)
|
2022-11-17 |
2024-05-23 |
The Broad Institute, Inc. |
Prime editor delivery by aav
|
|
JP2025540052A
(ja)
|
2022-12-01 |
2025-12-11 |
イェール ユニバーシティー |
細胞内ペイロード送達用刺激応答性トレースレス操作プラットフォーム
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
WO2024121354A1
(en)
|
2022-12-08 |
2024-06-13 |
Keygene N.V. |
Duplex sequencing with covalently closed dna ends
|
|
WO2024138087A2
(en)
|
2022-12-23 |
2024-06-27 |
The Broad Institute, Inc. |
Methods and compositions for modulating cellular factors to increase prime editing efficiencies
|
|
GB202219829D0
(en)
|
2022-12-29 |
2023-02-15 |
Ivy Farm Tech Limited |
Genetically manipulated cells
|
|
EP4642225A1
(en)
|
2022-12-29 |
2025-11-05 |
Vilmorin & Cie |
Tomato plants resistant to resistance-breaking tswv strains and corresponding resistance genes
|
|
EP4652272A1
(en)
|
2023-01-18 |
2025-11-26 |
The Broad Institute Inc. |
Prime editing-mediated readthrough of premature termination codons (pert)
|
|
WO2024155745A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Base editing-mediated readthrough of premature termination codons (bert)
|
|
GB202300905D0
(en)
|
2023-01-20 |
2023-03-08 |
Nicoventures Trading Ltd |
Method
|
|
WO2024161358A1
(en)
|
2023-02-01 |
2024-08-08 |
Dlf Seeds A/S |
Beet yellows virus resistance
|
|
WO2024170505A1
(en)
|
2023-02-13 |
2024-08-22 |
Institut National de la Santé et de la Recherche Médicale |
Methods of treatment of iron overload associated diseases
|
|
WO2024173645A1
(en)
|
2023-02-15 |
2024-08-22 |
Arbor Biotechnologies, Inc. |
Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript
|
|
GB202303077D0
(en)
|
2023-03-02 |
2023-04-19 |
Univ Oslo |
Brassica plants with improved seed retention
|
|
WO2024192108A1
(en)
|
2023-03-14 |
2024-09-19 |
Evolveimmune Therapeutics, Inc. |
Genetically modified car t cells and methods of making and using the same
|
|
US12419265B2
(en)
|
2023-03-27 |
2025-09-23 |
Redsea Science And Technology Inc. |
Tomato plant designated ‘X21-02’
|
|
CN121152635A
(zh)
|
2023-03-31 |
2025-12-16 |
布里卡尔治疗公司 |
用于增强细胞疫苗的免疫原性的方法
|
|
WO2024209000A1
(en)
|
2023-04-04 |
2024-10-10 |
Keygene N.V. |
Linkers for duplex sequencing
|
|
US20240344079A1
(en)
|
2023-04-14 |
2024-10-17 |
Seminis Vegetable Seeds, Inc. |
Methods and compositions for peronospora resistance in spinach
|
|
WO2024216116A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
WO2024216118A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
IT202300007968A1
(it)
|
2023-04-21 |
2024-10-21 |
Fond Telethon Ets |
Metodi di editing genomico e costrutti
|
|
WO2024223402A1
(en)
|
2023-04-24 |
2024-10-31 |
Institut National de la Santé et de la Recherche Médicale |
Biallelic gene mutations for the diagnosis of neonatal systemic hypertension
|
|
WO2024226499A1
(en)
|
2023-04-24 |
2024-10-31 |
The Broad Institute, Inc. |
Compositions and methods for modifying fertility
|
|
WO2024223900A1
(en)
|
2023-04-28 |
2024-10-31 |
Vilmorin & Cie |
Genetic determinants conferring improved tobrfv resistance
|
|
WO2024236547A1
(en)
|
2023-05-18 |
2024-11-21 |
Inceptor Bio, Llc |
Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
|
|
WO2024243438A2
(en)
|
2023-05-23 |
2024-11-28 |
Omega Therapeutics, Inc. |
Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
|
|
WO2025003305A1
(en)
|
2023-06-28 |
2025-01-02 |
Vilmorin & Cie |
Pepper resistance to meloidogyne enterolobii
|
|
WO2025003461A1
(en)
|
2023-06-30 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Methods of treatment of metabolic disorders
|
|
WO2025022290A1
(en)
|
2023-07-21 |
2025-01-30 |
Crispr Therapeutics Ag |
Modulating expression of alas1 (5'-aminolevulinate synthase 1) gene
|
|
WO2025021893A1
(en)
|
2023-07-24 |
2025-01-30 |
Vilmorin & Cie |
Resistance to cysdv in melons
|
|
WO2025046513A1
(en)
|
2023-08-29 |
2025-03-06 |
Inceptor Bio, Llc |
Methods of manufacturing myeloid-derived cells from hematopoietic stem cells and compositions and uses thereof
|
|
EP4520334A1
(en)
|
2023-09-07 |
2025-03-12 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025052001A1
(en)
|
2023-09-07 |
2025-03-13 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025059215A1
(en)
|
2023-09-12 |
2025-03-20 |
Aadigen, Llc |
Methods and compositions for treating or preventing cancer
|
|
WO2025064408A1
(en)
|
2023-09-18 |
2025-03-27 |
The Broad Institute, Inc. |
Compositions and methods for treating cardiovascular disease
|
|
WO2025064678A2
(en)
|
2023-09-20 |
2025-03-27 |
The Broad Institute, Inc. |
Prime editing-mediated readthrough of frameshift mutations (perf)
|
|
GB202314578D0
(en)
|
2023-09-22 |
2023-11-08 |
Univ Manchester |
Methods of producing homoplasmic modified plants or parts thereof
|
|
WO2025101938A2
(en)
|
2023-11-10 |
2025-05-15 |
Century Therapeutics, Inc. |
Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
|
|
WO2025106626A1
(en)
|
2023-11-15 |
2025-05-22 |
Century Therapeutics, Inc. |
Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
|
|
WO2025128981A1
(en)
|
2023-12-14 |
2025-06-19 |
Sohm, Inc. |
Compositions and methods for genome editing
|
|
WO2025163107A1
(en)
|
2024-02-01 |
2025-08-07 |
Institut Gustave Roussy |
Immune cells defective for znf217 and uses thereof
|
|
WO2025186726A1
(en)
|
2024-03-05 |
2025-09-12 |
Crispr Therapeutics Ag |
Modulating expression of agt (angiotensinogen) gene
|
|
WO2025186284A1
(en)
|
2024-03-05 |
2025-09-12 |
Vilmorin & Cie |
Increased yield in cucumber
|
|
WO2025207795A1
(en)
|
2024-03-26 |
2025-10-02 |
Juno Therapeutics, Inc. |
Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof
|
|
WO2025207798A1
(en)
|
2024-03-26 |
2025-10-02 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof
|
|
WO2025215354A1
(en)
|
2024-04-08 |
2025-10-16 |
Ivy Farm Technologies Limited |
Method of culturing an animal cell
|
|
US20250332260A1
(en)
|
2024-04-10 |
2025-10-30 |
Garuda Therapeutics, Inc. |
Immune compatible cells for allogeneic cell therapies to cover global, ethnic, or disease-specific populations
|
|
WO2025217398A1
(en)
|
2024-04-10 |
2025-10-16 |
Lyell Immunopharma, Inc. |
Methods for culturing cells with improved culture medium
|
|
WO2025224715A1
(en)
|
2024-04-26 |
2025-10-30 |
King Abdullah Univeristy Of Science And Technology |
Methods for improving precise genome modification and reducing unwanted mutations by crispr-cas editing
|
|
WO2025235388A1
(en)
|
2024-05-06 |
2025-11-13 |
Regeneron Pharmaceuticals, Inc. |
Transgene genomic identification by nuclease-mediated long read sequencing
|
|
WO2025247951A1
(en)
|
2024-05-28 |
2025-12-04 |
Institut Gustave Roussy |
Fyn kinase inhibitors, combinations and uses thereof
|
|
US20250382627A1
(en)
|
2024-06-13 |
2025-12-18 |
J.R. Simplot Company |
Engineering remontant flowering in rosaceae
|