US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
US20110239315A1
(en)
|
2009-01-12 |
2011-09-29 |
Ulla Bonas |
Modular dna-binding domains and methods of use
|
CA2765488C
(en)
|
2009-06-30 |
2018-01-02 |
Sangamo Biosciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
KR102110725B1
(ko)
|
2009-12-10 |
2020-05-13 |
리전츠 오브 더 유니버스티 오브 미네소타 |
Tal 이펙터-매개된 dna 변형
|
AU2011215557B2
(en)
*
|
2010-02-09 |
2016-03-10 |
Sangamo Therapeutics, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
CA2796600C
(en)
*
|
2010-04-26 |
2019-08-13 |
Sangamo Biosciences, Inc. |
Genome editing of a rosa locus using zinc-finger nucleases
|
AU2011256838B2
(en)
*
|
2010-05-17 |
2014-10-09 |
Sangamo Therapeutics, Inc. |
Novel DNA-binding proteins and uses thereof
|
BR122021005287B1
(pt)
|
2010-06-02 |
2022-02-22 |
Evolva, Inc |
Hospedeiro recombinante que compreende um gene recombinante para produção de esteviol ou glicosídeo de esteviol
|
EP2392208B1
(en)
*
|
2010-06-07 |
2016-05-04 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use
|
WO2011159369A1
(en)
*
|
2010-06-14 |
2011-12-22 |
Iowa State University Research Foundation, Inc. |
Nuclease activity of tal effector and foki fusion protein
|
WO2012012667A2
(en)
|
2010-07-21 |
2012-01-26 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of a hla locus
|
EP3461898A1
(en)
*
|
2011-02-25 |
2019-04-03 |
The University Court Of The University of Edinburgh |
Genetically modified animals and methods for making the same
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
US9315788B2
(en)
*
|
2011-04-05 |
2016-04-19 |
Cellectis, S.A. |
Method for the generation of compact TALE-nucleases and uses thereof
|
BR112013025567B1
(pt)
|
2011-04-27 |
2021-09-21 |
Amyris, Inc |
Métodos para modificação genômica
|
AU2012266597B2
(en)
|
2011-06-06 |
2016-09-22 |
Bayer Cropscience Nv |
Methods and means to modify a plant genome at a preselected site
|
EP3461896B1
(en)
*
|
2011-07-15 |
2023-11-29 |
The General Hospital Corporation |
Methods of transcription activator like effector assembly
|
AU2012286901B2
(en)
|
2011-07-25 |
2016-10-27 |
Sangamo Therapeutics, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
|
EP2736538A4
(en)
|
2011-07-27 |
2015-08-05 |
Broad Inst Inc |
COMPOSITIONS AND METHODS FOR TREATING HEAD AND NECK CANCER
|
EP2737066B1
(en)
*
|
2011-07-29 |
2017-11-08 |
Cellectis |
High throughput method for assembly and cloning polynucleotides comprising highly similar polynucleotidic modules
|
WO2013019745A1
(en)
*
|
2011-07-29 |
2013-02-07 |
Georgia Health Sciences University |
Methods and compositions for genetically modifiying cells
|
CN102787125B
(zh)
*
|
2011-08-05 |
2013-12-04 |
北京大学 |
一种构建tale重复序列的方法
|
KR102114493B1
(ko)
|
2011-08-08 |
2020-05-26 |
에볼바 에스아 |
스테비올 글리코시드의 재조합 생산
|
WO2013026740A2
(en)
|
2011-08-22 |
2013-02-28 |
Bayer Cropscience Nv |
Methods and means to modify a plant genome
|
IL277027B
(en)
|
2011-09-21 |
2022-07-01 |
Sangamo Therapeutics Inc |
Methods and preparations for regulating transgene expression
|
WO2013050593A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013050318A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013050611A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013053711A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013053686A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013053730A1
(en)
|
2011-10-12 |
2013-04-18 |
Bayer Cropscience Ag |
Plants with decreased activity of a starch dephosphorylating enzyme
|
US20140251317A1
(en)
|
2011-10-12 |
2014-09-11 |
Bayer Cropscience Ag |
Plants with decreased activity of a starch dephosphorylating enzyme
|
DK2784157T3
(da)
|
2011-10-21 |
2019-10-21 |
Univ Kyushu Nat Univ Corp |
Designfremgangsmåde til et rna-bindende protein under anvendelse af ppr-motiv og anvendelse deraf
|
AU2012328682B2
(en)
*
|
2011-10-27 |
2017-09-21 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of the HPRT locus
|
US20150159166A1
(en)
|
2011-10-31 |
2015-06-11 |
Pioneer Hi Bred International Inc |
Plant drought tolerance and nitrogen use efficiency by reducing plant sensitivity to ethylene
|
WO2013074999A1
(en)
|
2011-11-16 |
2013-05-23 |
Sangamo Biosciences, Inc. |
Modified dna-binding proteins and uses thereof
|
US20130137173A1
(en)
*
|
2011-11-30 |
2013-05-30 |
Feng Zhang |
Nucleotide-specific recognition sequences for designer tal effectors
|
US8450107B1
(en)
*
|
2011-11-30 |
2013-05-28 |
The Broad Institute Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
US10801017B2
(en)
|
2011-11-30 |
2020-10-13 |
The Broad Institute, Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
RU2624139C2
(ru)
|
2011-12-05 |
2017-06-30 |
Фэктор Байосайенс Инк. |
Способы и препараты для трансфекции клеток
|
CN104080462B
(zh)
|
2011-12-16 |
2019-08-09 |
塔尔盖特基因生物技术有限公司 |
用于修饰预定的靶核酸序列的组合物和方法
|
DE102011122267A1
(de)
|
2011-12-23 |
2013-06-27 |
Kws Saat Ag |
Neue aus Pflanzen stammende cis-regulatorische Elemente für die Entwicklung Pathogen-responsiver chimärer Promotoren
|
WO2013101877A2
(en)
|
2011-12-29 |
2013-07-04 |
Iowa State University Research Foundation, Inc. |
Genetically modified plants with resistance to xanthomonas and other bacterial plant pathogens
|
GB201122458D0
(en)
|
2011-12-30 |
2012-02-08 |
Univ Wageningen |
Modified cascade ribonucleoproteins and uses thereof
|
EP2612918A1
(en)
|
2012-01-06 |
2013-07-10 |
BASF Plant Science Company GmbH |
In planta recombination
|
EA201400995A1
(ru)
|
2012-03-13 |
2015-02-27 |
Юниверсити Оф Гуэлф |
Способы повышения выносливости к тепловому стрессу и содержания аминокислот в растениях
|
WO2013136274A1
(en)
|
2012-03-13 |
2013-09-19 |
University Of Guelph |
Myb55 promoter and use thereof
|
DK3415158T3
(da)
*
|
2012-03-15 |
2021-01-11 |
Cellectis |
Repeat-variable direster til targeting af nukleotider
|
SG11201405956SA
(en)
|
2012-03-23 |
2014-11-27 |
Cellectis |
Method to overcome dna chemical modifications sensitivity of engineered tale dna binding domains
|
CN102628037B
(zh)
*
|
2012-03-31 |
2013-07-24 |
西南大学 |
家蚕油蚕基因BmBlos2遗传改造系统及其制备方法和应用
|
US20130274129A1
(en)
*
|
2012-04-04 |
2013-10-17 |
Geneart Ag |
Tal-effector assembly platform, customized services, kits and assays
|
US20130280222A1
(en)
|
2012-04-18 |
2013-10-24 |
Board Of Regents Of The University Of Texas System |
Non-disruptive gene targeting
|
EP2841581B2
(en)
|
2012-04-23 |
2023-03-08 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome engineering in plants
|
IN2014DN09261A
(no)
|
2012-04-25 |
2015-07-10 |
Regeneron Pharma |
|
US9523098B2
(en)
|
2012-05-02 |
2016-12-20 |
Dow Agrosciences Llc |
Targeted modification of malate dehydrogenase
|
CA2871524C
(en)
|
2012-05-07 |
2021-07-27 |
Sangamo Biosciences, Inc. |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
US11120889B2
(en)
|
2012-05-09 |
2021-09-14 |
Georgia Tech Research Corporation |
Method for synthesizing a nuclease with reduced off-site cleavage
|
PE20190844A1
(es)
|
2012-05-25 |
2019-06-17 |
Emmanuelle Charpentier |
Modulacion de transcripcion con arn de direccion a adn generico
|
US9605274B2
(en)
|
2012-05-25 |
2017-03-28 |
Evolutionary Genomics, Inc. |
Dirigent gene EG261 and its orthologs and paralogs and their uses for pathogen resistance in plants
|
CN104884624B
(zh)
|
2012-05-25 |
2017-07-25 |
进化基因组股份有限公司 |
Dirigent基因EG261及其直系同源物和旁系同源物以及它们在植物中用于病原体抗性的用途
|
EP3279315A3
(en)
*
|
2012-05-25 |
2018-02-28 |
Cellectis |
Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
EP2855671B1
(en)
*
|
2012-06-05 |
2019-02-20 |
Cellectis |
Transcription activator-like effector (tale) fusion protein
|
JP6423987B2
(ja)
|
2012-06-07 |
2018-11-14 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia |
制御された遺伝子発現方法
|
EP2858486A4
(en)
|
2012-06-12 |
2016-04-13 |
Hoffmann La Roche |
METHODS AND COMPOSITIONS FOR GENERATING ALLLETS WITH CONDITIONAL INACTIVATION
|
CA2876426A1
(en)
|
2012-06-15 |
2013-12-19 |
E. I. Du Pont De Nemours And Company |
Methods and compositions involving als variants with native substrate preference
|
US20150225734A1
(en)
*
|
2012-06-19 |
2015-08-13 |
Regents Of The University Of Minnesota |
Gene targeting in plants using dna viruses
|
AR091482A1
(es)
*
|
2012-06-21 |
2015-02-04 |
Recombinetics Inc |
Celulas modificadas geneticamente y metodos par su obtencion
|
US20150291951A1
(en)
*
|
2012-06-22 |
2015-10-15 |
Mayo Foundation For Medical Education And Research |
Genome editing
|
JP6293660B2
(ja)
|
2012-07-06 |
2018-03-14 |
国立研究開発法人農業・食品産業技術総合研究機構 |
着粒数が増加したコムギ及びその生産方法、並びにコムギの着粒数を増加させるための薬剤
|
DK3444342T3
(da)
|
2012-07-11 |
2020-08-24 |
Sangamo Therapeutics Inc |
Fremgangsmåder og sammensætninger til behandlingen af lysosomale aflejringssygdomme
|
US20140072961A1
(en)
*
|
2012-07-11 |
2014-03-13 |
University of Nevada, Las Vegas |
Method of Genome Surgery with Paired, Permeant Endonuclease Excision
|
EP2872154B1
(en)
|
2012-07-11 |
2017-05-31 |
Sangamo BioSciences, Inc. |
Methods and compositions for delivery of biologics
|
EP2687605A1
(en)
|
2012-07-19 |
2014-01-22 |
Biogemma |
Method for performing homologous recombination
|
US20140230083A1
(en)
|
2012-07-24 |
2014-08-14 |
Cellectis |
Modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins
|
JP2015527889A
(ja)
*
|
2012-07-25 |
2015-09-24 |
ザ ブロード インスティテュート, インコーポレイテッド |
誘導可能なdna結合タンパク質およびゲノム撹乱ツール、ならびにそれらの適用
|
US10058078B2
(en)
|
2012-07-31 |
2018-08-28 |
Recombinetics, Inc. |
Production of FMDV-resistant livestock by allele substitution
|
UA118957C2
(uk)
|
2012-08-29 |
2019-04-10 |
Сангамо Біосайєнсиз, Інк. |
Спосіб і композиція для лікування генетичного захворювання
|
EP2893016B1
(en)
*
|
2012-09-03 |
2019-06-19 |
Cellectis |
Methods for modulating tal specificity
|
EP4148134A1
(en)
*
|
2012-09-04 |
2023-03-15 |
The Scripps Research Institute |
Chimeric polypeptides having targeted binding specificity
|
US9914930B2
(en)
|
2012-09-07 |
2018-03-13 |
Dow Agrosciences Llc |
FAD3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
WO2014043143A1
(en)
|
2012-09-11 |
2014-03-20 |
Life Technologies Corporation |
Nucleic acid amplification
|
EP2895620B1
(en)
|
2012-09-11 |
2017-08-02 |
Life Technologies Corporation |
Nucleic acid amplification
|
EP3789405A1
(en)
|
2012-10-12 |
2021-03-10 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
EP2914714A4
(en)
*
|
2012-10-30 |
2016-09-21 |
Recombinetics Inc |
CONTROLLING GENDER TREATMENT IN ANIMALS
|
CA2890160A1
(en)
|
2012-10-31 |
2014-05-08 |
Cellectis |
Coupling herbicide resistance with targeted insertion of transgenes in plants
|
BR112015009967B1
(pt)
|
2012-11-01 |
2022-07-12 |
Medicago Inc. |
Método para a produção de um polipeptídeo terapêutico
|
JP6510416B2
(ja)
|
2012-11-01 |
2019-05-08 |
ファクター バイオサイエンス インコーポレイテッド |
細胞中でタンパク質を発現するための方法および生成物
|
JP2015534834A
(ja)
*
|
2012-11-20 |
2015-12-07 |
ジェイ.アール.シンプロット カンパニー |
Talにより媒介されるトランファーdna挿入
|
AU2013355327A1
(en)
*
|
2012-12-05 |
2015-06-11 |
Sangamo Therapeutics, Inc. |
Methods and compositions for regulation of metabolic disorders
|
SG10202107423UA
(en)
|
2012-12-06 |
2021-08-30 |
Sigma Aldrich Co Llc |
Crispr-based genome modification and regulation
|
CN103013954B
(zh)
*
|
2012-12-17 |
2014-03-05 |
中国科学院遗传与发育生物学研究所 |
水稻基因badh2的定点敲除系统及其应用
|
US9708589B2
(en)
|
2012-12-18 |
2017-07-18 |
Monsanto Technology Llc |
Compositions and methods for custom site-specific DNA recombinases
|
PL2934097T3
(pl)
|
2012-12-21 |
2018-11-30 |
Cellectis |
Ziemniaki o ograniczonej słodkości indukowanej chłodem
|
AU2013361220A1
(en)
|
2012-12-21 |
2015-04-02 |
Pioneer Hi-Bred International, Inc. |
Compositions and methods for auxin-analog conjugation
|
SG10201705926YA
(en)
|
2013-02-06 |
2017-08-30 |
Evolva Sa |
Methods for improved production of rebaudioside d and rebaudioside m
|
CA2900338A1
(en)
*
|
2013-02-07 |
2014-08-14 |
The General Hospital Corporation |
Tale transcriptional activators
|
BR112015019160A2
(pt)
|
2013-02-11 |
2017-08-22 |
Dalgaard Mikkelsen Michael |
Produção de glicosídeos de esteviol em hospedeiros recombinantes
|
CN103319574A
(zh)
*
|
2013-02-16 |
2013-09-25 |
清华大学 |
分离的多肽及其应用
|
EP2958990B1
(en)
|
2013-02-20 |
2019-10-16 |
Regeneron Pharmaceuticals, Inc. |
Genetic modification of rats
|
WO2014128659A1
(en)
|
2013-02-21 |
2014-08-28 |
Cellectis |
Method to counter-select cells or organisms by linking loci to nuclease components
|
WO2014130955A1
(en)
|
2013-02-25 |
2014-08-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
WO2014134412A1
(en)
*
|
2013-03-01 |
2014-09-04 |
Regents Of The University Of Minnesota |
Talen-based gene correction
|
CN105473721A
(zh)
|
2013-03-11 |
2016-04-06 |
先锋国际良种公司 |
采用磺酰脲类依赖型稳定化结构域的方法和组合物
|
NZ712727A
(en)
|
2013-03-14 |
2017-05-26 |
Caribou Biosciences Inc |
Compositions and methods of nucleic acid-targeting nucleic acids
|
WO2014153234A1
(en)
|
2013-03-14 |
2014-09-25 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
WO2014153242A1
(en)
|
2013-03-14 |
2014-09-25 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
WO2014144094A1
(en)
*
|
2013-03-15 |
2014-09-18 |
J.R. Simplot Company |
Tal-mediated transfer dna insertion
|
EP2966983B1
(en)
|
2013-03-15 |
2021-07-28 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the fad2-1a/1b genes
|
US11039586B2
(en)
|
2013-03-15 |
2021-06-22 |
Monsanto Technology Llc |
Creation and transmission of megaloci
|
BR112015022522B1
(pt)
*
|
2013-03-15 |
2023-09-26 |
Regents Of The University Of Minnesota |
Método para a modificação do material genômico em uma célula vegetal e vetor viral
|
US10793867B2
(en)
|
2013-03-15 |
2020-10-06 |
Monsanto Technology, Llc |
Methods for targeted transgene-integration using custom site-specific DNA recombinases
|
US10113162B2
(en)
|
2013-03-15 |
2018-10-30 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes
|
AU2014247151A1
(en)
|
2013-04-02 |
2015-10-08 |
Bayer Cropscience Nv |
Targeted genome engineering in eukaryotes
|
US10501748B2
(en)
|
2013-04-05 |
2019-12-10 |
Dow Agrosciences Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
WO2014169810A1
(zh)
*
|
2013-04-16 |
2014-10-23 |
深圳华大基因科技服务有限公司 |
分离的寡核苷酸及其用途
|
PT3456831T
(pt)
|
2013-04-16 |
2021-09-10 |
Regeneron Pharma |
Modificação alvejada do genoma de rato
|
KR102326842B1
(ko)
|
2013-04-22 |
2021-11-15 |
고쿠리쓰다이가쿠호진 규슈다이가쿠 |
피피알 모티프를 가지는 디앤에이 결합성 단백질을 포함하는 융합 단백질
|
EP2796558A1
(en)
|
2013-04-23 |
2014-10-29 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Improved gene targeting and nucleic acid carrier molecule, in particular for use in plants
|
CN103233004B
(zh)
*
|
2013-04-28 |
2015-04-29 |
新疆农垦科学院 |
一种人工dna分子及检测目标基因表达的方法
|
WO2014186435A2
(en)
|
2013-05-14 |
2014-11-20 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for reducing neointima formation
|
EP3008186B1
(en)
|
2013-06-14 |
2018-11-28 |
Cellectis |
Methods for non-transgenic genome editing in plants
|
CA2915837A1
(en)
*
|
2013-06-17 |
2014-12-24 |
The Broad Institute, Inc. |
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
|
EP2818867A1
(en)
|
2013-06-27 |
2014-12-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies conjugated to at least one nucleic acid molecule and their use in multiplex immuno-detection assays
|
WO2015002780A1
(en)
*
|
2013-07-01 |
2015-01-08 |
The Board Of Regents Of The University Of Texas System |
Transcription activator-like effector (tale) libraries and methods of synthesis and use
|
US10563225B2
(en)
|
2013-07-26 |
2020-02-18 |
President And Fellows Of Harvard College |
Genome engineering
|
WO2015017866A1
(en)
|
2013-08-02 |
2015-02-05 |
Enevolv, Inc. |
Processes and host cells for genome, pathway, and biomolecular engineering
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
JP5931022B2
(ja)
|
2013-08-09 |
2016-06-08 |
国立大学法人広島大学 |
Dna結合ドメインを含むポリペプチド
|
US10006011B2
(en)
|
2013-08-09 |
2018-06-26 |
Hiroshima University |
Polypeptide containing DNA-binding domain
|
EA036362B1
(ru)
|
2013-09-04 |
2020-10-30 |
Квс Заат Се |
Растение, устойчивое к гельминтоспориозу
|
DE102013014637A1
(de)
|
2013-09-04 |
2015-03-05 |
Kws Saat Ag |
HELMlNTHOSPORlUM TURClCUM-RESlSTENTE PFLANZE
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
MX2016003182A
(es)
|
2013-09-11 |
2017-03-31 |
Arsia Therapeutics Inc |
Formulaciones de proteínas líquidas que contienen líquidos iónicos.
|
WO2015042585A1
(en)
*
|
2013-09-23 |
2015-03-26 |
Rensselaer Polytechnic Institute |
Nanoparticle-mediated gene delivery, genomic editing and ligand-targeted modification in various cell populations
|
US10329578B2
(en)
|
2013-10-18 |
2019-06-25 |
Pioneer Hi-Bred International, Inc. |
Glyphosate-N-acetyltransferase (GLYAT) sequences and methods of use
|
ES2962492T3
(es)
|
2013-10-25 |
2024-03-19 |
Livestock Improvement Corporation Ltd |
Marcadores genéticos y usos de los mismos
|
CA3100536A1
(en)
|
2013-11-03 |
2015-05-07 |
The Regents Of The University Of California |
Ionic liquids for transdermal drug delivery
|
KR102269371B1
(ko)
|
2013-11-04 |
2021-06-28 |
코르테바 애그리사이언스 엘엘씨 |
최적 메이즈 유전자좌
|
MX362066B
(es)
|
2013-11-04 |
2019-01-07 |
Dow Agrosciences Llc |
Loci óptimos de soya.
|
EP3862434A1
(en)
|
2013-11-04 |
2021-08-11 |
Dow AgroSciences LLC |
Optimal soybean loci
|
KR102269769B1
(ko)
|
2013-11-04 |
2021-06-28 |
코르테바 애그리사이언스 엘엘씨 |
최적 메이즈 유전자좌
|
US20160264995A1
(en)
|
2013-11-06 |
2016-09-15 |
Hiroshima University |
Vector for Nucleic Acid Insertion
|
WO2015070062A1
(en)
*
|
2013-11-07 |
2015-05-14 |
Massachusetts Institute Of Technology |
Cell-based genomic recorded accumulative memory
|
EP2878667A1
(en)
|
2013-11-29 |
2015-06-03 |
Institut Pasteur |
TAL effector means useful for partial or full deletion of DNA tandem repeats
|
CN103710360A
(zh)
*
|
2013-12-03 |
2014-04-09 |
南方医科大学珠江医院 |
提高HepGL肝癌细胞氨基甲酰磷酸合成酶表达的方法
|
EP3080279B1
(en)
|
2013-12-11 |
2018-09-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a genome
|
US9546384B2
(en)
|
2013-12-11 |
2017-01-17 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a mouse genome
|
WO2015089486A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
CA2932472A1
(en)
|
2013-12-12 |
2015-06-18 |
Massachusetts Institute Of Technology |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
EP3653229A1
(en)
|
2013-12-12 |
2020-05-20 |
The Broad Institute, Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for genome editing
|
EP3080611B1
(en)
|
2013-12-13 |
2018-11-14 |
The General Hospital Corporation |
Soluble high molecular weight (hmw) tau species and applications thereof
|
WO2015092460A1
(en)
|
2013-12-18 |
2015-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New gene mutations for the diagnosis of arthrogryposis multiplex congenita and congenital peripheral neuropathies disease
|
JP6652489B2
(ja)
|
2013-12-19 |
2020-02-26 |
アミリス, インコーポレイテッド |
ゲノム組込みのための方法
|
WO2015116969A2
(en)
*
|
2014-01-30 |
2015-08-06 |
The Board Of Trustees Of The University Of Arkansas |
Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
|
RU2714404C2
(ru)
|
2014-01-31 |
2020-02-14 |
Фэктор Байосайенс Инк. |
Способы и продукты для получения и доставки нуклеиновых кислот
|
LT3102673T
(lt)
|
2014-02-03 |
2020-08-25 |
Sangamo Therapeutics, Inc. |
Beta talasemijos gydymo būdai ir kompozicijos
|
CN104844696A
(zh)
*
|
2014-02-19 |
2015-08-19 |
北京大学 |
一种转录激活子样效应因子功能蛋白设计、合成及其应用
|
TW201538518A
(zh)
|
2014-02-28 |
2015-10-16 |
Dow Agrosciences Llc |
藉由嵌合基因調控元件所賦予之根部特異性表現
|
DK3115457T3
(da)
*
|
2014-03-05 |
2019-11-04 |
Univ Kobe Nat Univ Corp |
Fremgangsmåde til modificering af genomsekvens til specifikt at konvertere nukleinsyrebaser af målrettet dna-sekvens og molekylært kompleks til anvendelse i samme
|
MX2016011690A
(es)
|
2014-03-21 |
2016-11-07 |
Univ Leland Stanford Junior |
Edicion del genoma sin nucleasas.
|
AU2015236033B2
(en)
|
2014-03-26 |
2018-06-07 |
University Of Maryland, College Park |
Targeted genome editing in zygotes of domestic large animals
|
US10507232B2
(en)
*
|
2014-04-02 |
2019-12-17 |
University Of Florida Research Foundation, Incorporated |
Materials and methods for the treatment of latent viral infection
|
WO2015164748A1
(en)
|
2014-04-24 |
2015-10-29 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (tale) proteins
|
BR122023023211A2
(pt)
|
2014-04-28 |
2024-01-23 |
Recombinetics, Inc. |
Método de fazer edições de genes multiplex em uma célula de vertebrado ou de embrião primário não-humano
|
CN104611365B
(zh)
*
|
2014-07-17 |
2017-06-16 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
WO2015165276A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒
|
WO2015165275A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
DE102014106327A1
(de)
|
2014-05-07 |
2015-11-12 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
TAL-Effektornuklease zum gezielten Knockout des HIV-Korezeptors CCR5
|
US11918695B2
(en)
|
2014-05-09 |
2024-03-05 |
Yale University |
Topical formulation of hyperbranched polymer-coated particles
|
PL3140269T3
(pl)
|
2014-05-09 |
2024-03-11 |
Yale University |
Cząstki pokryte hiperrozgałęzionym poliglicerolem oraz sposoby ich wytwarzania i zastosowania
|
WO2015175642A2
(en)
|
2014-05-13 |
2015-11-19 |
Sangamo Biosciences, Inc. |
Methods and compositions for prevention or treatment of a disease
|
SG11201609634YA
(en)
|
2014-06-06 |
2016-12-29 |
Regeneron Pharma |
Methods and compositions for modifying a targeted locus
|
WO2015188870A1
(en)
|
2014-06-12 |
2015-12-17 |
Sesvanderhave N.V. |
Use of selectable marker gene in sugar beet protoplasts transformation method and system
|
EA201692565A1
(ru)
|
2014-06-12 |
2017-05-31 |
Сесвандерхаве Н.В. |
Способ трансформации протопластов сахарной свеклы на платформе технологии talen
|
WO2015193858A1
(en)
|
2014-06-20 |
2015-12-23 |
Cellectis |
Potatoes with reduced granule-bound starch synthase
|
HUE049405T2
(hu)
|
2014-06-23 |
2020-09-28 |
Regeneron Pharma |
Nukleáz-közvetített DNS-összeállítás
|
RU2711740C2
(ru)
|
2014-06-26 |
2020-01-21 |
Регенерон Фармасьютикалз, Инк. |
Способы и композиции для нацеленных генетических модификаций и способы их применения
|
WO2016000237A1
(en)
|
2014-07-03 |
2016-01-07 |
Pioneer Overseas Corporation |
Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
CN106572688B
(zh)
|
2014-08-11 |
2022-01-25 |
埃沃尔瓦公司 |
在重组宿主中生产甜菊醇糖苷
|
US11071289B2
(en)
|
2014-08-14 |
2021-07-27 |
Biocytogen Boston Corp |
DNA knock-in system
|
CN105367628B
(zh)
*
|
2014-08-19 |
2019-07-26 |
深圳华大基因农业控股有限公司 |
一对高效编辑水稻waxy基因的talen其识别打靶位点及其应用
|
CN105367631B
(zh)
*
|
2014-08-25 |
2019-05-14 |
深圳华大基因科技有限公司 |
一种转录激活子样效应因子核酸酶及其编码基因和应用
|
BR112017001470A2
(pt)
|
2014-09-07 |
2018-02-20 |
Selecta Biosciences Inc |
métodos e composições para atenuar as respostas imunes do vetor de transferência anti-viral de terapia genética
|
US10612064B2
(en)
|
2014-09-09 |
2020-04-07 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
KR101528812B1
(ko)
*
|
2014-09-18 |
2015-06-15 |
강원대학교산학협력단 |
SETDB1 HMTase 발현 저해방법
|
CN105440111B
(zh)
*
|
2014-09-30 |
2019-08-13 |
深圳华大基因研究院 |
一对转录激活子样效应因子核酸酶及其编码序列与应用
|
MX2017004306A
(es)
|
2014-10-01 |
2017-12-20 |
Eagle Biologics Inc |
Formulaciones de polisacáridos y ácido nucleico que contienen agentes de reducción de viscosidad.
|
CN104357440B
(zh)
*
|
2014-10-09 |
2017-06-13 |
中山大学 |
一对靶向斑马鱼Forkhead box n1基因的Talen识别序列及其mRNA制备方法
|
WO2016057961A1
(en)
|
2014-10-10 |
2016-04-14 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
ES2741387T3
(es)
|
2014-10-15 |
2020-02-10 |
Regeneron Pharma |
Métodos y composiciones para generar o mantener células pluripotentes
|
WO2016066671A1
(en)
|
2014-10-29 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating resistant cancers using progastrin inhibitors
|
US10920215B2
(en)
|
2014-11-04 |
2021-02-16 |
National University Corporation Kobe University |
Method for modifying genome sequence to introduce specific mutation to targeted DNA sequence by base-removal reaction, and molecular complex used therein
|
US20170369848A1
(en)
*
|
2014-11-11 |
2017-12-28 |
Q Therapeutics, Inc. |
Engineering mesenchymal stem cells using homologous recombination
|
EP3218393A1
(en)
|
2014-11-12 |
2017-09-20 |
Recombinetics, Inc. |
Heterozygous modifications of tumor suppressor genes and swine model of neurofibromatosis type 1
|
DE102014016667B4
(de)
|
2014-11-12 |
2024-03-07 |
Kws Saat Se |
Haploideninduktoren
|
US20160138040A1
(en)
*
|
2014-11-13 |
2016-05-19 |
Cellectis |
Brassica engineered to confer herbicide tolerance
|
WO2016094867A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Protected guide rnas (pgrnas)
|
WO2016100333A1
(en)
|
2014-12-15 |
2016-06-23 |
Syngenta Participations Ag |
Pesticidal microrna carriers and use thereof
|
MX2017008190A
(es)
|
2014-12-19 |
2018-03-23 |
Regeneron Pharma |
Metodos y composiciones para la modificacion genetica dirigida a traves de direccionamiento multiple de una sola etapa.
|
US9963710B2
(en)
|
2014-12-23 |
2018-05-08 |
Syngenta Participations Ag |
Methods and compositions for identifying and enriching for cells comprising site specific genomic modifications
|
WO2016118560A1
(en)
*
|
2015-01-20 |
2016-07-28 |
Mayo Foundation For Medical Education And Research |
Methods and materials for assembling nucleic acid constructs
|
AU2016211671B2
(en)
|
2015-01-26 |
2022-05-26 |
Fate Therapeutics, Inc. |
Methods and compositions for inducing hematopoietic cell differentiation
|
EP3250686A1
(en)
|
2015-01-30 |
2017-12-06 |
Evolva SA |
Production of steviol glycosides in recombinant hosts
|
JP2018508203A
(ja)
|
2015-02-02 |
2018-03-29 |
セレクティス |
T−dna組込みを伴わない、アグロバクテリウムが介在するゲノム改変
|
US10485196B2
(en)
|
2015-02-03 |
2019-11-26 |
The Institute Of Genetics And Developmental Biology Chinese Academy Of Scinces |
Rice plants with altered seed phenotype and quality
|
US10793868B2
(en)
|
2015-02-03 |
2020-10-06 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Plants with increased seed size
|
JP6929791B2
(ja)
|
2015-02-09 |
2021-09-01 |
デューク ユニバーシティ |
エピゲノム編集のための組成物および方法
|
WO2016128523A1
(en)
|
2015-02-12 |
2016-08-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the responsiveness of a patient affected with malignant hematological disease to chemotherapy treatment and methods of treatment of such disease
|
JP7199809B2
(ja)
|
2015-02-13 |
2023-01-06 |
ファクター バイオサイエンス インコーポレイテッド |
核酸製品及びその投与方法
|
JP6590333B2
(ja)
*
|
2015-02-26 |
2019-10-16 |
学校法人東京理科大学 |
Dna結合ドメイン組込み用ベクターおよびそのセット、融合タンパク質コーディングベクターおよびそのセットならびにその製造方法、デスティネーションベクター、植物細胞用発現ベクターおよびその製造方法、植物細胞用発現ベクター作製用キット、形質転換方法、ならびにゲノム編集方法
|
CA2977685C
(en)
|
2015-03-02 |
2024-02-20 |
Sinai Health System |
Homologous recombination factors
|
WO2016142427A1
(en)
|
2015-03-10 |
2016-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method ank kit for reprogramming somatic cells
|
EP3271457B1
(en)
|
2015-03-16 |
2021-01-20 |
DSM IP Assets B.V. |
Udp-glycosyltransferases
|
WO2016153305A1
(ko)
*
|
2015-03-26 |
2016-09-29 |
한국생명공학연구원 |
표적 유전자 특이적 핵산 프로브 및 Fok Ι 제한효소 이량체를 이용하여 세포 내에서 표적 유전자를 특이적으로 편집하기 위한 조성물 및 이의 용도
|
CA2981509A1
(en)
*
|
2015-03-30 |
2016-10-06 |
The Board Of Regents Of The Nevada System Of Higher Educ. On Behalf Of The University Of Nevada, La |
Compositions comprising talens and methods of treating hiv
|
WO2016161446A1
(en)
|
2015-04-03 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
EP4008780A1
(en)
|
2015-04-30 |
2022-06-08 |
The Trustees of Columbia University in the City of New York |
Gene therapy for autosomal dominant diseases
|
US11845928B2
(en)
|
2015-05-04 |
2023-12-19 |
Tsinghua University |
Methods and kits for fragmenting DNA
|
EP3095870A1
(en)
|
2015-05-19 |
2016-11-23 |
Kws Saat Se |
Methods for the in planta transformation of plants and manufacturing processes and products based and obtainable therefrom
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
ES2594486B1
(es)
|
2015-06-19 |
2017-09-26 |
Biopraxis Research Aie |
Molécula de ácido nucleico, proteína de fusión y método para modificar el material genético de una célula
|
CA2991054C
(en)
|
2015-06-30 |
2024-03-12 |
Regents Of The University Of Minnesota |
Haploid inducer line for accelerated genome editing
|
US10988775B2
(en)
|
2015-07-17 |
2021-04-27 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Wheat plants resistant to powdery mildew
|
AU2016297167A1
(en)
|
2015-07-23 |
2018-02-22 |
Mayo Foundation For Medical Education And Research |
Editing mitochondrial DNA
|
US10837041B2
(en)
|
2015-08-07 |
2020-11-17 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
AU2016308339A1
(en)
|
2015-08-18 |
2018-04-12 |
Baylor College Of Medicine |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
CN108135941B
(zh)
|
2015-08-19 |
2021-07-27 |
儿研所儿童医学中心 |
用于治疗移植物抗宿主病的组合物和方法
|
CN108271384B
(zh)
*
|
2015-09-09 |
2022-04-15 |
国立大学法人神户大学 |
用于特异性转变靶向dna序列的核酸碱基的革兰氏阳性菌的基因组序列的转变方法、及其使用的分子复合体
|
US10837024B2
(en)
|
2015-09-17 |
2020-11-17 |
Cellectis |
Modifying messenger RNA stability in plant transformations
|
WO2017066561A2
(en)
|
2015-10-16 |
2017-04-20 |
President And Fellows Of Harvard College |
Regulatory t cell pd-1 modulation for regulating t cell effector immune responses
|
US10167457B2
(en)
|
2015-10-23 |
2019-01-01 |
President And Fellows Of Harvard College |
Nucleobase editors and uses thereof
|
WO2017075261A1
(en)
|
2015-10-27 |
2017-05-04 |
Recombinetics, Inc. |
Engineering of humanized car t-cells and platelets by genetic complementation
|
CA3002676A1
(en)
|
2015-10-29 |
2017-05-04 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids
|
SG11201803145RA
(en)
|
2015-11-04 |
2018-05-30 |
Fate Therapeutics Inc |
Methods and compositions for inducing hematopoietic cell differentiation
|
WO2017079428A1
(en)
|
2015-11-04 |
2017-05-11 |
President And Fellows Of Harvard College |
Site specific germline modification
|
WO2017079673A1
(en)
|
2015-11-04 |
2017-05-11 |
Fate Therapeutics, Inc. |
Genomic engineering of pluripotent cells
|
US11001622B2
(en)
|
2015-11-19 |
2021-05-11 |
The Brigham And Women's Hospital, Inc. |
Method of treating autoimmune disease with lymphocyte antigen CD5-like (CD5L) protein
|
EP3173485B1
(de)
|
2015-11-27 |
2021-08-25 |
KWS SAAT SE & Co. KGaA |
Kühletolerante pflanze
|
JP6923205B2
(ja)
|
2015-11-27 |
2021-08-18 |
国立大学法人神戸大学 |
標的化したdna配列の核酸塩基を特異的に変換する、単子葉植物のゲノム配列の変換方法、及びそれに用いる分子複合体
|
AU2016374253B2
(en)
|
2015-12-18 |
2021-10-21 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the MHC cell receptor
|
US11352631B2
(en)
|
2015-12-18 |
2022-06-07 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the T cell receptor
|
DE102015017161A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
US11840693B2
(en)
|
2015-12-21 |
2023-12-12 |
KWS SAAT SE & Co. KGaA |
Restorer plants
|
DE102015016445A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
MY196175A
(en)
|
2016-01-11 |
2023-03-20 |
Univ Leland Stanford Junior |
Chimeric Proteins And Methods Of Regulating Gene Expression
|
MY194127A
(en)
|
2016-01-11 |
2022-11-14 |
Univ Leland Stanford Junior |
Chimeric proteins and methods of immunotherapy
|
EP3410843A1
(en)
|
2016-02-02 |
2018-12-12 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes
|
US20200308590A1
(en)
|
2016-02-16 |
2020-10-01 |
Yale University |
Compositions and methods for treatment of cystic fibrosis
|
EP3416976A2
(en)
|
2016-02-16 |
2018-12-26 |
Yale University |
Compositions for enhancing targeted gene editing and methods of use thereof
|
US20190249172A1
(en)
|
2016-02-18 |
2019-08-15 |
The Regents Of The University Of California |
Methods and compositions for gene editing in stem cells
|
EP3881857A1
(en)
|
2016-02-18 |
2021-09-22 |
The Penn State Research Foundation |
Generating gabaergic neurons in brains
|
CA3014871A1
(en)
|
2016-02-26 |
2017-08-31 |
Cellectis |
Micelle based system nuclease encapsulation for in-vivo gene editing
|
CN109414414A
(zh)
|
2016-03-16 |
2019-03-01 |
戴维·格拉德斯通研究所 |
用于治疗肥胖症和/或糖尿病以及用于鉴定候选治疗剂的方法和组合物
|
US20210309965A1
(en)
|
2016-03-21 |
2021-10-07 |
Dana-Farber Cancer Institute, Inc. |
T-cell exhaustion state-specific gene expression regulators and uses thereof
|
US20190119337A1
(en)
|
2016-03-23 |
2019-04-25 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
US20190117799A1
(en)
|
2016-04-01 |
2019-04-25 |
The Brigham And Women's Hospital, Inc. |
Stimuli-responsive nanoparticles for biomedical applications
|
CA3020671A1
(en)
|
2016-04-13 |
2017-10-19 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
US20190062734A1
(en)
|
2016-04-13 |
2019-02-28 |
Editas Medicine, Inc. |
Grna fusion molecules, gene editing systems, and methods of use thereof
|
CA3020857A1
(en)
*
|
2016-04-14 |
2017-10-19 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
WO2017178585A1
(en)
|
2016-04-15 |
2017-10-19 |
Cellectis |
A method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation
|
CN107312788B
(zh)
*
|
2016-04-26 |
2020-07-28 |
中国科学院动物研究所 |
一种tale重复序列载体的构建方法
|
WO2017192512A2
(en)
|
2016-05-02 |
2017-11-09 |
Massachusetts Institute Of Technology |
Amphiphilic nanoparticles for delivery of crispr based therapy
|
US10815514B2
(en)
|
2016-05-16 |
2020-10-27 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
EP4219731A3
(en)
|
2016-05-18 |
2023-08-09 |
Amyris, Inc. |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
|
CN105950623B
(zh)
*
|
2016-05-19 |
2018-11-30 |
电子科技大学 |
一种用于talen高效构建的双rvd单元模块库及talen构建方法
|
CN109476715B
(zh)
|
2016-05-26 |
2023-06-27 |
纽海姆有限公司 |
产无籽果实的植物
|
US11293021B1
(en)
|
2016-06-23 |
2022-04-05 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
EP3474849A4
(en)
|
2016-06-27 |
2020-07-29 |
The Broad Institute, Inc. |
COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF DIABETES
|
CA3029271A1
(en)
|
2016-06-28 |
2018-01-04 |
Cellectis |
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
|
CN105949293B
(zh)
*
|
2016-06-28 |
2019-08-13 |
福建农林大学 |
植物源高效转录激活功能域sac3及应用
|
US11466291B2
(en)
|
2016-07-06 |
2022-10-11 |
Cellectis |
Sequential gene editing in primary immune cells
|
CA3030587A1
(en)
|
2016-07-15 |
2018-01-18 |
Salk Institute For Biological Studies |
Methods and compositions for genome editing in non-dividing cells
|
CA3031206A1
(en)
|
2016-07-29 |
2018-02-01 |
Regeneron Pharmaceuticals, Inc. |
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy
|
IL308426A
(en)
|
2016-08-03 |
2024-01-01 |
Harvard College |
Adenosine nuclear base editors and their uses
|
CN109804066A
(zh)
|
2016-08-09 |
2019-05-24 |
哈佛大学的校长及成员们 |
可编程cas9-重组酶融合蛋白及其用途
|
US20190183101A1
(en)
|
2016-08-11 |
2019-06-20 |
The Jackson Laboratory |
Methods and compositions relating to improved human red blood cell survival in genetically modified immunodeficient non-human animals
|
IL264439B1
(en)
|
2016-08-17 |
2024-04-01 |
Factor Bioscience Inc |
A suitable viral preparation containing a synthetic messenger RNA encoding a gene editing protein for use in cancer treatment and a synthetic messenger RNA encoding a gene editing protein for use in therapy
|
CN109844107A
(zh)
|
2016-08-17 |
2019-06-04 |
孟山都技术公司 |
通过操纵赤霉素代谢增加可收获产量的用于矮株型植物的方法和组合物
|
CA3034271A1
(en)
|
2016-08-18 |
2018-02-22 |
Cellectis |
Black-spot resistant potatoes with reduced tuber-specific polyphenol oxidase activity
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
AU2017315414B2
(en)
|
2016-08-24 |
2024-02-15 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
EP3503927A1
(en)
|
2016-08-29 |
2019-07-03 |
The Regents of the University of California |
Topical formulations based on ionic species for skin treatment
|
CA3035484A1
(en)
|
2016-09-01 |
2018-03-08 |
Cellectis |
Methods for altering amino acid content in plants
|
US10960085B2
(en)
|
2016-09-07 |
2021-03-30 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
AU2017332721B2
(en)
|
2016-09-20 |
2023-11-09 |
Sara BUHRLAGE |
Compositions and methods for identification, assessment, prevention, and treatment of AML using USP10 biomarkers and modulators
|
US20180084767A1
(en)
|
2016-09-21 |
2018-03-29 |
Recombinetics, Inc. |
Animal models for cardiomyopathy
|
US20190225974A1
(en)
|
2016-09-23 |
2019-07-25 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome optimization in plants
|
JP6887492B6
(ja)
|
2016-10-04 |
2021-07-14 |
プレシジョン バイオサイエンシズ,インク. |
遺伝子改変細胞で使用するための共刺激ドメイン
|
WO2018069232A1
(en)
|
2016-10-10 |
2018-04-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of having cardiac hypertrophy
|
UA127311C2
(uk)
|
2016-10-10 |
2023-07-19 |
Лімагрен Юроп |
Нуклеїнова кислота, що кодує резистентність sm1 до оранжевої злакової галиці, і спосіб її застосування
|
AU2017342543A1
(en)
|
2016-10-14 |
2019-05-02 |
President And Fellows Of Harvard College |
AAV delivery of nucleobase editors
|
GB201617559D0
(en)
|
2016-10-17 |
2016-11-30 |
University Court Of The University Of Edinburgh The |
Swine comprising modified cd163 and associated methods
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
US20190249183A1
(en)
|
2016-10-24 |
2019-08-15 |
Javier Gil Humanes |
Multiplex gene targeting in plants
|
WO2018076335A1
(en)
|
2016-10-31 |
2018-05-03 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Compositions and methods for enhancing abiotic stress tolerance
|
WO2018144097A1
(en)
|
2016-11-04 |
2018-08-09 |
Akeagen Llc |
Genetically modified non-human animals and methods for producing heavy chain-only antibodies
|
CN110100006A
(zh)
|
2016-11-07 |
2019-08-06 |
埃沃尔瓦公司 |
重组宿主中甜菊糖苷的生产
|
US11312972B2
(en)
|
2016-11-16 |
2022-04-26 |
Cellectis |
Methods for altering amino acid content in plants through frameshift mutations
|
JP6948718B2
(ja)
|
2016-11-28 |
2021-10-13 |
国立大学法人大阪大学 |
ゲノム編集方法
|
US10975388B2
(en)
|
2016-12-14 |
2021-04-13 |
Ligandal, Inc. |
Methods and compositions for nucleic acid and protein payload delivery
|
US20200085758A1
(en)
|
2016-12-16 |
2020-03-19 |
The Brigham And Women's Hospital, Inc. |
Co-delivery of nucleic acids for simultaneous suppression and expression of target genes
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
JP6971478B2
(ja)
*
|
2016-12-27 |
2021-11-24 |
国立研究開発法人農業・食品産業技術総合研究機構 |
ゲノム編集植物の作出方法
|
WO2018129270A1
(en)
|
2017-01-05 |
2018-07-12 |
Fred Hutchinson Cancer Research Center |
Systems and methods to improve vaccine efficacy
|
GB201700380D0
(en)
|
2017-01-10 |
2017-02-22 |
Plant Bioscience Ltd |
Methods of increasing seed yield
|
IL301053A
(en)
|
2017-01-23 |
2023-05-01 |
Regeneron Pharma |
HSD17B13 variants and their uses
|
CN110573623A
(zh)
|
2017-02-09 |
2019-12-13 |
福建农林大学 |
用于提高植物产量的磷酸盐转运蛋白的表达
|
CA3054031A1
(en)
|
2017-02-22 |
2018-08-30 |
Crispr Therapeutics Ag |
Compositions and methods for gene editing
|
EP3366778A1
(de)
|
2017-02-28 |
2018-08-29 |
Kws Saat Se |
Haploidisierung in sorghum
|
CA3054926A1
(en)
|
2017-03-03 |
2018-09-07 |
Pioneer Hi-Bred International, Inc. |
Non-destructive assay for soybean seeds using near infrared analysis
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
US11542496B2
(en)
|
2017-03-10 |
2023-01-03 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
CA3057289A1
(en)
|
2017-03-21 |
2018-09-27 |
The Jackson Laboratory |
A genetically modified mouse expressing human apoe4 and mouse trem2 p.r47h and methods of use thereof
|
SG11201908782XA
(en)
|
2017-03-22 |
2019-10-30 |
Univ Kobe Nat Univ Corp |
Method for converting nucleic acid sequence of cell specifically converting nucleic acid base of targeted dna using cell endogenous dna modifying enzyme, and molecular complex used therein
|
JP7191388B2
(ja)
|
2017-03-23 |
2022-12-19 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
核酸によってプログラム可能なdna結合蛋白質を含む核酸塩基編集因子
|
CN110603264A
(zh)
|
2017-03-24 |
2019-12-20 |
中国科学院遗传与发育生物学研究所 |
用于增加籽粒产量的方法
|
EP3600269A1
(en)
|
2017-03-24 |
2020-02-05 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Gfi1 inhibitors for the treatment of hyperglycemia
|
WO2018181863A1
(ja)
|
2017-03-30 |
2018-10-04 |
国立大学法人東京大学 |
異なる複数の目的遺伝子の評価方法
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
WO2018187493A1
(en)
|
2017-04-04 |
2018-10-11 |
Yale University |
Compositions and methods for in utero delivery
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
WO2018191520A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Respiratory and sweat gland ionocytes
|
EP3392339A1
(en)
|
2017-04-18 |
2018-10-24 |
Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen |
Improved genome editing in plant cells
|
WO2018195486A1
(en)
|
2017-04-21 |
2018-10-25 |
The Broad Institute, Inc. |
Targeted delivery to beta cells
|
AU2018260469A1
(en)
|
2017-04-25 |
2019-11-14 |
Cellectis |
Alfalfa with reduced lignin composition
|
CN116693411A
(zh)
|
2017-04-28 |
2023-09-05 |
爱康泰生治疗公司 |
用于递送核酸的新型羰基脂质和脂质纳米颗粒制剂
|
EP3619322A4
(en)
|
2017-05-03 |
2021-06-30 |
Sangamo Therapeutics, Inc. |
METHODS AND COMPOSITIONS FOR MODIFICATION OF A TRANSMEMBRANARY CONDUCTANCE REGULATORY GENE IN MUCOVISCIDOSIS (CFTR)
|
WO2018204777A2
(en)
|
2017-05-05 |
2018-11-08 |
The Broad Institute, Inc. |
Methods for identification and modification of lncrna associated with target genotypes and phenotypes
|
JP7170666B2
(ja)
|
2017-05-08 |
2022-11-14 |
プレシジョン バイオサイエンシズ,インク. |
操作された抗原受容体をコードする核酸分子及び阻害性核酸分子、並びにそれらの使用方法
|
EP3621433B1
(en)
|
2017-05-12 |
2022-07-27 |
The Jackson Laboratory |
Nsg mice lacking mhc class i and class ii
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
WO2018211032A1
(en)
|
2017-05-17 |
2018-11-22 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
CN111032684A
(zh)
|
2017-05-25 |
2020-04-17 |
中国科学院遗传与发育生物学研究所 |
提高谷物生产率的方法
|
EP3409104A1
(en)
|
2017-05-31 |
2018-12-05 |
Vilmorin et Cie |
Tomato plant resistant to tomato yellow leaf curl virus, powdery mildew, and nematodes
|
EP3409106A1
(en)
|
2017-06-01 |
2018-12-05 |
Vilmorin et Cie |
Tolerance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus (tbrfv)
|
WO2020249996A1
(en)
|
2019-06-14 |
2020-12-17 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus
|
US11879128B2
(en)
|
2017-06-05 |
2024-01-23 |
Consejo Superior De Investigaciones Científicas (Csic)—Delegación Andalucía |
Targeting of gluten by genome editing
|
MX2019014661A
(es)
|
2017-06-05 |
2020-07-29 |
Regeneron Pharma |
Variantes de b4galt1 y usos de estas.
|
EP3634496A4
(en)
|
2017-06-06 |
2021-09-08 |
Dana-Farber Cancer Institute, Inc. |
METHOD FOR RISING AWARENESS IN CANCER CELLS AGAINST T-CELL-MEDIATED KILLING BY MODULATING MOLECULAR SIGNAL PATHS
|
US11421208B2
(en)
|
2017-06-13 |
2022-08-23 |
Regents Of The University Of Minnesota |
Materials and methods for increasing gene editing frequency
|
EP3638218A4
(en)
|
2017-06-14 |
2021-06-09 |
The Broad Institute, Inc. |
COMPOSITIONS AND METHOD OF TARGETING COMPLEMENTING COMPONENT 3 FOR INHIBITION OF TUMOR GROWTH
|
US20200362355A1
(en)
|
2017-06-15 |
2020-11-19 |
The Regents Of The University Of California |
Targeted non-viral dna insertions
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
EP3641785A1
(en)
|
2017-06-19 |
2020-04-29 |
Cellectis |
Anti-hbv combination therapies involving specific endonucleases
|
WO2018234370A1
(en)
|
2017-06-20 |
2018-12-27 |
Institut Curie |
DEFECTIVE IMMUNE CELLS AGAINST SUV39H1
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
EP3642346A1
(en)
|
2017-06-23 |
2020-04-29 |
University of Kentucky Research Foundation |
Method
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
KR20200031618A
(ko)
|
2017-06-26 |
2020-03-24 |
더 브로드 인스티튜트, 인코퍼레이티드 |
표적화된 핵산 편집을 위한 crispr/cas-아데닌 데아미나아제 기반 조성물, 시스템 및 방법
|
US11053484B2
(en)
|
2017-06-30 |
2021-07-06 |
Precision Biosciences, Inc. |
Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene
|
HRP20220615T1
(hr)
|
2017-06-30 |
2022-06-24 |
Inscripta, Inc. |
Postupci, moduli, instrumenti i sustavi za automatiziranu obradu stanica
|
CN111094573A
(zh)
*
|
2017-07-12 |
2020-05-01 |
梅约医学教育与研究基金会 |
有效靶向敲入或基因置换的材料和方法
|
EP3658573A1
(en)
|
2017-07-28 |
2020-06-03 |
President and Fellows of Harvard College |
Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace)
|
WO2019024081A1
(zh)
*
|
2017-08-04 |
2019-02-07 |
北京大学 |
特异性识别甲基化修饰dna碱基的tale rvd及其应用
|
WO2019033053A1
(en)
|
2017-08-11 |
2019-02-14 |
Recombinetics, Inc. |
INDUCIBLE DISEASE MODELS, METHODS OF MAKING AND USING THEM IN TISSUE COMPLEMENTATION
|
EP3447134B1
(en)
|
2017-08-22 |
2023-10-11 |
KWS SAAT SE & Co. KGaA |
Increased fungal resistance in crop plants
|
EP3673054A4
(en)
|
2017-08-22 |
2021-06-02 |
Napigen, Inc. |
MODIFICATION OF THE GENOME OF ORGANITES USING POLYNUCLEOTID-GUIDED ENDONUCLEASE
|
WO2019038417A1
(en)
|
2017-08-25 |
2019-02-28 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
METHODS FOR INCREASING GRAIN YIELD
|
US10738327B2
(en)
|
2017-08-28 |
2020-08-11 |
Inscripta, Inc. |
Electroporation cuvettes for automation
|
US11697822B2
(en)
|
2017-08-29 |
2023-07-11 |
KWS SAAT SE & Co. KGaA |
Blue aleurone and other segregation systems
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
US11884928B2
(en)
|
2017-09-18 |
2024-01-30 |
Amyris, Inc. |
Methods for genetic engineering Kluyveromyces host cells
|
BR112020005166A2
(pt)
|
2017-09-18 |
2020-09-24 |
Amyris, Inc. |
métodos para integração genômica para células hospedeiras de kluyveromyces
|
EP3684389A4
(en)
|
2017-09-21 |
2021-06-16 |
Dana Farber Cancer Institute, Inc. |
INSULATION, PRESERVATION, COMPOSITIONS AND USES OF EXTRACTS FROM JUSTICIA PLANTS
|
AU2018338790B2
(en)
|
2017-09-29 |
2022-09-15 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized TTR locus and methods of use
|
EP3687621A4
(en)
|
2017-09-30 |
2021-08-11 |
Inscripta, Inc. |
CONTINUOUS FLOW ELECTROPORATION INSTRUMENTATION
|
EP3692057B9
(en)
|
2017-10-03 |
2023-10-04 |
Precision BioSciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
US20200255828A1
(en)
|
2017-10-04 |
2020-08-13 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
MX2020003838A
(es)
|
2017-10-13 |
2020-08-06 |
Selecta Biosciences Inc |
Metodos y composiciones para atenuar las respuestas de inmunoglobulina m del vector de transferencia antiviral.
|
EP3697906A1
(en)
|
2017-10-16 |
2020-08-26 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
MX2020004444A
(es)
|
2017-10-19 |
2020-07-22 |
Cellectis |
Integracion genica direccionada de genes de inhibidores de nk para terapia con celulas inmunes mejorada.
|
KR20230034416A
(ko)
|
2017-10-27 |
2023-03-09 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
내인성 t 세포 수용체의 표적화된 대체
|
CN111868075A
(zh)
|
2017-10-31 |
2020-10-30 |
维尔莫林公司 |
包含雄性育性恢复等位基因的小麦
|
EP3704238B1
(en)
|
2017-11-01 |
2024-01-03 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
US20210363260A1
(en)
|
2017-11-13 |
2021-11-25 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
EP3713644A1
(en)
|
2017-11-20 |
2020-09-30 |
University of Georgia Research Foundation, Inc. |
Compositions and methods for modulating hif-2& x391; to improve muscle generation and repair
|
WO2019106163A1
(en)
|
2017-12-01 |
2019-06-06 |
Cellectis |
Reprogramming of genetically engineered primary immune cells
|
CA3078682A1
(en)
|
2017-12-15 |
2019-06-20 |
Dana-Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
BR112020011017A2
(pt)
|
2017-12-22 |
2020-11-17 |
Fate Therapeutics, Inc. |
células efetoras imunes intensificadas e uso das mesmas
|
DK3501268T3
(da)
|
2017-12-22 |
2021-11-08 |
Kws Saat Se & Co Kgaa |
Regenerering af planter i tilstedeværelse af histondeacetylase hæmmere
|
CN107868123B
(zh)
|
2017-12-25 |
2020-05-12 |
中国农业科学院作物科学研究所 |
一种同时提高植物产量和抗性的基因及其应用
|
EP3508581A1
(en)
|
2018-01-03 |
2019-07-10 |
Kws Saat Se |
Regeneration of genetically modified plants
|
BR112020014168A2
(pt)
|
2018-01-12 |
2020-12-08 |
Basf Se |
Proteína, ácido nucleico isolado, gene recombinante, vetor, célula hospedeira, planta, parte de planta ou semente de trigo, métodos para produzir, produto de trigo, farinha, farelo integral, amido, grânulos de amido ou farelo de trigo e métodos para identificar e/ou selecionar uma planta de trigo
|
EP3751990A1
(en)
|
2018-02-14 |
2020-12-23 |
Institute Of Genetics And Developmental Biology Chinese Academy of Sciences |
Methods of increasing nutrient use efficiency
|
AR114124A1
(es)
|
2018-02-15 |
2020-07-22 |
Monsanto Technology Llc |
Composiciones y métodos para mejorar el rendimiento de cultivos a través de apilamiento de rasgos
|
KR20200139679A
(ko)
|
2018-02-26 |
2020-12-14 |
안톨알엑스, 인크. |
면역관용성 리포솜 및 그의 사용 방법
|
EP4186921A1
(en)
|
2018-03-23 |
2023-05-31 |
The Trustees of Columbia University in the City of New York |
Gene editing for autosomal dominant diseases
|
CN111148833B
(zh)
|
2018-03-26 |
2021-04-02 |
国立大学法人神户大学 |
改变细胞具有的双链dna的目标部位的方法
|
EP3545756A1
(en)
|
2018-03-28 |
2019-10-02 |
KWS SAAT SE & Co. KGaA |
Regeneration of plants in the presence of inhibitors of the histone methyltransferase ezh2
|
WO2019185920A1
(en)
|
2018-03-29 |
2019-10-03 |
Cellectis |
Tale-nucleases for allele-specific codon modification
|
SG11202008977UA
(en)
|
2018-03-29 |
2020-10-29 |
Fate Therapeutics Inc |
Engineered immune effector cells and use thereof
|
US10435662B1
(en)
|
2018-03-29 |
2019-10-08 |
Inscripta, Inc. |
Automated control of cell growth rates for induction and transformation
|
EP3772928A4
(en)
|
2018-04-06 |
2021-12-29 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
GB201805865D0
(en)
|
2018-04-09 |
2018-05-23 |
Innes John Centre |
Genes
|
US10376889B1
(en)
|
2018-04-13 |
2019-08-13 |
Inscripta, Inc. |
Automated cell processing instruments comprising reagent cartridges
|
DK3560330T3
(da)
|
2018-04-24 |
2022-07-11 |
Kws Saat Se & Co Kgaa |
Planter med forbedret fordøjelighed og markørhaplotyper
|
US10858761B2
(en)
|
2018-04-24 |
2020-12-08 |
Inscripta, Inc. |
Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
|
US10557216B2
(en)
|
2018-04-24 |
2020-02-11 |
Inscripta, Inc. |
Automated instrumentation for production of T-cell receptor peptide libraries
|
WO2019209926A1
(en)
|
2018-04-24 |
2019-10-31 |
Inscripta, Inc. |
Automated instrumentation for production of peptide libraries
|
TWI686477B
(zh)
*
|
2018-04-25 |
2020-03-01 |
國立成功大學 |
特異性造成植物葉綠體基因變異的轉殖載體、套組、方法及利用其產生之轉殖植物細胞與農桿菌
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
US20210147831A1
(en)
|
2018-04-27 |
2021-05-20 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
JP2021521874A
(ja)
|
2018-05-02 |
2021-08-30 |
セレクティスCellectis |
増大した食物繊維を含むコムギの操作
|
WO2019213660A2
(en)
|
2018-05-04 |
2019-11-07 |
The Broad Institute, Inc. |
Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
|
EP3567111A1
(en)
|
2018-05-09 |
2019-11-13 |
KWS SAAT SE & Co. KGaA |
Gene for resistance to a pathogen of the genus heterodera
|
MX2020012028A
(es)
|
2018-05-11 |
2021-03-29 |
Crispr Therapeutics Ag |
Metodos y composiciones para tratar el cancer.
|
GB201808424D0
(en)
|
2018-05-23 |
2018-07-11 |
Lucite Int Uk Ltd |
Methods for producing BMA and MMA using genetically modified microorganisms
|
WO2019232542A2
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
GB201809273D0
(en)
|
2018-06-06 |
2018-07-25 |
Vib Vzw |
Novel mutant plant cinnamoyl-coa reductase proteins
|
WO2019234754A1
(en)
|
2018-06-07 |
2019-12-12 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) |
Nucleic acid constructs and methods of using same
|
SG11202011962TA
(en)
|
2018-06-07 |
2020-12-30 |
Brigham & Womens Hospital Inc |
Methods for generating hematopoietic stem cells
|
US20210337753A1
(en)
|
2018-06-07 |
2021-11-04 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization |
Methods of regenerating and transforming cannabis
|
EP3807301A1
(en)
|
2018-06-15 |
2021-04-21 |
KWS SAAT SE & Co. KGaA |
Methods for improving genome engineering and regeneration in plant ii
|
CN112566924A
(zh)
|
2018-06-15 |
2021-03-26 |
科沃施种子欧洲股份两合公司 |
改善植物中基因组工程化和再生的方法
|
US11291176B2
(en)
|
2018-06-15 |
2022-04-05 |
Nunhems B.V. |
Seedless watermelon plants comprising modifications in an ABC transporter gene
|
EP3807299A1
(en)
|
2018-06-15 |
2021-04-21 |
KWS SAAT SE & Co. KGaA |
Methods for enhancing genome engineering efficiency
|
WO2020006112A1
(en)
*
|
2018-06-26 |
2020-01-02 |
Regents Of The University Of Minnesota |
Delivery of developmental regulators to plants for the induction of meristematic tissue with genetic alterations
|
US20210324398A1
(en)
|
2018-06-29 |
2021-10-21 |
Pioneer Hi-Bred International, Inc. |
Edited nac genes in plants
|
CA3108767A1
(en)
|
2018-06-30 |
2020-01-02 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
CA3105331A1
(en)
|
2018-07-09 |
2020-01-16 |
Cellectis |
Canola with high oleic acid
|
JP7367974B2
(ja)
|
2018-07-31 |
2023-10-24 |
国立大学法人 東京大学 |
膜タンパク質活性測定法
|
US11939593B2
(en)
|
2018-08-01 |
2024-03-26 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for improving embryo development
|
GB201812603D0
(en)
|
2018-08-02 |
2018-09-19 |
British American Tobacco Investments Ltd |
Method
|
JP2021533742A
(ja)
|
2018-08-07 |
2021-12-09 |
株式会社モダリス |
新規転写アクチベーター
|
EP3607819A1
(en)
|
2018-08-10 |
2020-02-12 |
Vilmorin et Cie |
Resistance to xanthomonas campestris pv. campestris (xcc) in cauliflower
|
US10532324B1
(en)
|
2018-08-14 |
2020-01-14 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
US11142740B2
(en)
|
2018-08-14 |
2021-10-12 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
US20210317429A1
(en)
|
2018-08-20 |
2021-10-14 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
CN112867792A
(zh)
|
2018-08-23 |
2021-05-28 |
桑格摩生物治疗股份有限公司 |
工程化靶特异性碱基编辑器
|
BR112021003545A2
(pt)
|
2018-08-29 |
2021-05-18 |
Amyris, Inc. |
células e métodos para ensaio baseado em seleção
|
US11965154B2
(en)
|
2018-08-30 |
2024-04-23 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
CN109706155B
(zh)
*
|
2018-08-30 |
2022-04-19 |
南京农业大学 |
pOsHEN1::OsSPL14基因表达盒及其构建方法和应用
|
SG11202101984PA
(en)
|
2018-08-31 |
2021-03-30 |
Univ Yale |
Compositions and methods for enhancing triplex and nuclease-based gene editing
|
EP3623379A1
(en)
|
2018-09-11 |
2020-03-18 |
KWS SAAT SE & Co. KGaA |
Beet necrotic yellow vein virus (bnyvv)-resistance modifying gene
|
WO2020056170A1
(en)
|
2018-09-12 |
2020-03-19 |
Fred Hutchinson Cancer Research Center |
Reducing cd33 expression to selectively protect therapeutic cells
|
US20220088224A1
(en)
|
2018-09-18 |
2022-03-24 |
Vnv Newco Inc. |
Arc-based capsids and uses thereof
|
CN113015741A
(zh)
|
2018-09-18 |
2021-06-22 |
桑格摩生物治疗股份有限公司 |
程序性细胞死亡1(pd1)特异性核酸酶
|
GB201815672D0
(en)
|
2018-09-26 |
2018-11-07 |
Innes John Centre |
Methods for altering starch granule size profile
|
WO2020071528A1
(ja)
|
2018-10-04 |
2020-04-09 |
株式会社カネカ |
植物のゲノム編集に用いられるdna構築物
|
WO2020077236A1
(en)
|
2018-10-12 |
2020-04-16 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
CA3116452A1
(en)
|
2018-10-15 |
2020-04-23 |
Fondazione Telethon |
Genome editing methods and constructs
|
WO2020081173A1
(en)
|
2018-10-16 |
2020-04-23 |
Pioneer Hi-Bred International, Inc. |
Genome edited fine mapping and causal gene identification
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
AU2019365100A1
(en)
|
2018-10-22 |
2021-06-03 |
University Of Rochester |
Genome editing by directed non-homologous DNA insertion using a retroviral integrase-Cas9 fusion protein
|
CA3115534A1
(en)
|
2018-10-22 |
2020-04-30 |
Inscripta, Inc. |
Engineered nucleic acid-guided nucleases
|
US11214781B2
(en)
|
2018-10-22 |
2022-01-04 |
Inscripta, Inc. |
Engineered enzyme
|
EP3873525A4
(en)
|
2018-11-02 |
2022-07-13 |
Annexon, Inc. |
COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN INJURIES
|
GB201817971D0
(en)
|
2018-11-02 |
2018-12-19 |
British American Tobacco Investments Ltd |
Method
|
WO2020095107A1
(en)
|
2018-11-07 |
2020-05-14 |
Crispr Therapeutics Ag |
Anti-cd33 immune cell cancer therapy
|
US20200140815A1
(en)
|
2018-11-07 |
2020-05-07 |
Crispr Therapeutics Ag |
Anti-ptk7 immune cell cancer therapy
|
US20200231699A1
(en)
|
2018-11-07 |
2020-07-23 |
Crispr Therapeutics Ag |
Anti-liv1 immune cell cancer therapy
|
GB201818715D0
(en)
|
2018-11-16 |
2019-01-02 |
British American Tobacco Investments Ltd |
Method
|
BR112021010079A2
(pt)
|
2018-11-27 |
2021-11-23 |
Khona Scient Llc |
Armações multienzimáticas bidirecionais para a biossíntese de canabinoides
|
WO2020112195A1
(en)
|
2018-11-30 |
2020-06-04 |
Yale University |
Compositions, technologies and methods of using plerixafor to enhance gene editing
|
EP3891283A1
(en)
|
2018-12-05 |
2021-10-13 |
Vertex Pharmaceuticals Incorporated |
Gene-editing systems for editing a cystic fibrosis transmembrane regulator (cftr) gene
|
KR20200071198A
(ko)
|
2018-12-10 |
2020-06-19 |
네오이뮨텍, 인코퍼레이티드 |
Nrf2 발현 조절 기반 T 세포 항암면역치료법
|
GB201820109D0
(en)
|
2018-12-11 |
2019-01-23 |
Vib Vzw |
Plants with a lignin trait and udp-glycosyltransferase mutation
|
AU2019406778A1
(en)
|
2018-12-17 |
2021-07-22 |
Massachusetts Institute Of Technology |
Crispr-associated transposase systems and methods of use thereof
|
MX2021007400A
(es)
|
2018-12-20 |
2021-07-15 |
Regeneron Pharma |
Expansion de repeticiones mediada por nucleasas.
|
US20220090047A1
(en)
|
2018-12-21 |
2022-03-24 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
SG11202106987WA
(en)
|
2019-01-11 |
2021-07-29 |
Acuitas Therapeutics Inc |
Lipids for lipid nanoparticle delivery of active agents
|
WO2020150144A1
(en)
|
2019-01-15 |
2020-07-23 |
Seminis Vegetable Seeds, Inc. |
Green bean plants with improved disease resistance
|
GB201900940D0
(en)
|
2019-01-23 |
2019-03-13 |
British American Tobacco Investments Ltd |
Method
|
WO2020157573A1
(en)
|
2019-01-29 |
2020-08-06 |
The University Of Warwick |
Methods for enhancing genome engineering efficiency
|
WO2020161261A1
(en)
|
2019-02-06 |
2020-08-13 |
Vilmorin & Cie |
New gene responsible for cytoplasmic male sterility
|
US20230053540A1
(en)
|
2019-02-19 |
2023-02-23 |
Massachusetts Institute Of Technology |
Treatment of liver injury
|
WO2020178193A1
(en)
|
2019-03-01 |
2020-09-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method of treatment of sarcoidosis
|
WO2020181264A1
(en)
|
2019-03-07 |
2020-09-10 |
The Trustees Of Columbia University In The City Of New York |
Rna-guided dna integration using tn7-like transposons
|
EP3708651A1
(en)
|
2019-03-12 |
2020-09-16 |
KWS SAAT SE & Co. KGaA |
Improving plant regeneration
|
WO2020186237A1
(en)
|
2019-03-13 |
2020-09-17 |
The Broad Institute, Inc. |
Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof
|
DE112020001342T5
(de)
|
2019-03-19 |
2022-01-13 |
President and Fellows of Harvard College |
Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen
|
US11001831B2
(en)
|
2019-03-25 |
2021-05-11 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
EP3947691A4
(en)
|
2019-03-25 |
2022-12-14 |
Inscripta, Inc. |
SIMULTANEOUS MULTIPLEX GENOME EDITING IN A YEAST
|
SG11202108451VA
(en)
|
2019-04-03 |
2021-09-29 |
Regeneron Pharma |
Methods and compositions for insertion of antibody coding sequences into a safe harbor locus
|
CN113993999B
(zh)
|
2019-04-03 |
2022-11-22 |
精密生物科学公司 |
包含microRNA适应的shRNA(shRNAmiR)的遗传修饰的免疫细胞
|
IL286905B1
(en)
|
2019-04-04 |
2024-02-01 |
Regeneron Pharma |
Non-human animals containing the human coagulation factor 12 locus
|
KR102487901B1
(ko)
|
2019-04-04 |
2023-01-12 |
리제너론 파마슈티칼스 인코포레이티드 |
표적화된 변형의 표적화 벡터로의 무흔적 도입을 위한 방법
|
CA3136061A1
(en)
|
2019-04-05 |
2020-10-08 |
Osaka University |
Method for producing knock-in cell
|
EP3947646A1
(en)
|
2019-04-05 |
2022-02-09 |
Precision BioSciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
CN114096684A
(zh)
|
2019-05-13 |
2022-02-25 |
科沃施种子欧洲股份两合公司 |
玉米的耐旱性
|
GB201906768D0
(en)
|
2019-05-14 |
2019-06-26 |
British American Tobacco Investments Ltd |
Method
|
WO2020234426A1
(en)
|
2019-05-23 |
2020-11-26 |
Nanjing Agricultural University |
Methods for improving rice grain yield
|
AR118995A1
(es)
|
2019-05-25 |
2021-11-17 |
Kws Saat Se & Co Kgaa |
Mejorador de la inducción de haploides
|
US20220226464A1
(en)
|
2019-05-28 |
2022-07-21 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
BR112021023594A2
(pt)
|
2019-05-28 |
2022-02-08 |
Selecta Biosciences Inc |
Métodos e composições para resposta imune de vetor de transferência antiviral atenuada
|
US20220243178A1
(en)
|
2019-05-31 |
2022-08-04 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
JP2022534867A
(ja)
|
2019-06-04 |
2022-08-04 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ベータスリップ変異を有するヒト化ttr遺伝子座を含む非ヒト動物と使用方法
|
WO2020244759A1
(en)
|
2019-06-05 |
2020-12-10 |
Klemm & Sohn Gmbh & Co. Kg |
New plants having a white foliage phenotype
|
US10837021B1
(en)
|
2019-06-06 |
2020-11-17 |
Inscripta, Inc. |
Curing for recursive nucleic acid-guided cell editing
|
AU2020289581A1
(en)
|
2019-06-07 |
2021-11-18 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized albumin locus
|
US11845957B2
(en)
|
2019-06-14 |
2023-12-19 |
Regeneron Pharmaceuticals, Inc. |
Models of tauopathy
|
EP3987024A4
(en)
|
2019-06-20 |
2023-11-01 |
University Of Massachusetts |
COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITING
|
WO2020257395A1
(en)
|
2019-06-21 |
2020-12-24 |
Inscripta, Inc. |
Genome-wide rationally-designed mutations leading to enhanced lysine production in e. coli
|
WO2020254850A1
(en)
|
2019-06-21 |
2020-12-24 |
Vilmorin & Cie |
Improvement of quality and permanence of green color of peppers at maturity and over-maturity
|
US10927385B2
(en)
|
2019-06-25 |
2021-02-23 |
Inscripta, Inc. |
Increased nucleic-acid guided cell editing in yeast
|
EP3990009A1
(en)
|
2019-06-27 |
2022-05-04 |
CRISPR Therapeutics AG |
Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer
|
EP3757219A1
(en)
|
2019-06-28 |
2020-12-30 |
KWS SAAT SE & Co. KGaA |
Enhanced plant regeneration and transformation by using grf1 booster gene
|
GB201909563D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
GB201909562D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
CA3145863A1
(en)
|
2019-07-05 |
2021-01-14 |
Limagrain Europe |
Method for increasing yield in plants
|
AR122277A1
(es)
|
2019-07-11 |
2022-08-31 |
Univ California |
Métodos para la regeneración mejorada de plantas transgénicas utilizando el factor de regulación del crecimiento (grf), el factor de interacción con grf (gif) o genes grf-gif y proteínas quiméricos
|
JP2022542102A
(ja)
|
2019-07-23 |
2022-09-29 |
ムネモ・セラピューティクス |
Suv39h1欠損免疫細胞
|
FR3099178A1
(fr)
|
2019-07-24 |
2021-01-29 |
Soltis |
Tournesol à teneur élevée en acide oléique et procédé d’obtention
|
WO2021016608A1
(en)
|
2019-07-25 |
2021-01-28 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
US10501404B1
(en)
|
2019-07-30 |
2019-12-10 |
Factor Bioscience Inc. |
Cationic lipids and transfection methods
|
WO2021019272A1
(en)
|
2019-07-31 |
2021-02-04 |
Vilmorin & Cie |
Tolerance to tolcndv in cucumber
|
EP3772542A1
(en)
|
2019-08-07 |
2021-02-10 |
KWS SAAT SE & Co. KGaA |
Modifying genetic variation in crops by modulating the pachytene checkpoint protein 2
|
WO2021035054A1
(en)
|
2019-08-20 |
2021-02-25 |
Precision Biosciences, Inc. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
EP4021496A1
(en)
|
2019-08-30 |
2022-07-06 |
Yale University |
Compositions and methods for delivery of nucleic acids to cells
|
US20210079347A1
(en)
|
2019-09-06 |
2021-03-18 |
Crispr Therapeutics Ag |
Genetically engineered t cells having improved persistence in culture
|
WO2021061815A1
(en)
|
2019-09-23 |
2021-04-01 |
Omega Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR MODULATING HEPATOCYTE NUCLEAR FACTOR 4-ALPHA (HNF4α) GENE EXPRESSION
|
CN114391040A
(zh)
|
2019-09-23 |
2022-04-22 |
欧米茄治疗公司 |
用于调节载脂蛋白b(apob)基因表达的组合物和方法
|
US11542513B2
(en)
|
2019-09-26 |
2023-01-03 |
Seminis Vegetable Seeds, Inc. |
Lettuce plants having resistance to Nasonovia ribisnigri biotype Nr:1
|
GB201914137D0
(en)
|
2019-10-01 |
2019-11-13 |
Univ Leeds Innovations Ltd |
Modified Plants
|
AU2020366566A1
(en)
|
2019-10-17 |
2022-04-21 |
KWS SAAT SE & Co. KGaA |
Enhanced disease resistance of crops by downregulation of repressor genes
|
EP3808170A1
(en)
|
2019-10-17 |
2021-04-21 |
Bejo Zaden B.V. |
Lactuca sativa resistance to bremia lactucae
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
CN112779266A
(zh)
|
2019-11-06 |
2021-05-11 |
青岛清原化合物有限公司 |
在生物体内创制新基因的方法及应用
|
KR20220097414A
(ko)
|
2019-11-08 |
2022-07-07 |
리제너론 파마슈티칼스 인코포레이티드 |
X-연관 연소 망막층간분리 치료법을 위한 crispr 및 aav 전략
|
JP2023510457A
(ja)
|
2019-11-12 |
2023-03-14 |
カー・ヴェー・エス ザート エス・エー ウント コー. カー・ゲー・アー・アー |
ヘテロデラ属の病原体に対する耐性遺伝子
|
WO2021095847A1
(ja)
|
2019-11-14 |
2021-05-20 |
国立大学法人広島大学 |
抗原特異的受容体遺伝子を環状dnaを用いてt細胞ゲノムに導入する方法
|
WO2021094805A1
(en)
|
2019-11-14 |
2021-05-20 |
Vilmorin & Cie |
Resistance to acidovorax valerianellae in corn salad
|
JP7448120B2
(ja)
|
2019-11-14 |
2024-03-12 |
国立研究開発法人農業・食品産業技術総合研究機構 |
プラズマを用いてゲノム編集酵素を植物細胞内に導入する方法
|
US11203762B2
(en)
|
2019-11-19 |
2021-12-21 |
Inscripta, Inc. |
Methods for increasing observed editing in bacteria
|
WO2021108363A1
(en)
|
2019-11-25 |
2021-06-03 |
Regeneron Pharmaceuticals, Inc. |
Crispr/cas-mediated upregulation of humanized ttr allele
|
JP2023505039A
(ja)
|
2019-11-27 |
2023-02-08 |
カリックス インコーポレイテッド |
遺伝子編集のためのtalエフェクターヌクレアーゼ
|
CA3160096A1
(en)
|
2019-12-06 |
2021-06-10 |
Bruce J. Mccreedy Jr. |
Methods for cancer immunotherapy
|
CN114787347A
(zh)
|
2019-12-10 |
2022-07-22 |
因思科瑞普特公司 |
新颖的mad核酸酶
|
EP4074821A4
(en)
|
2019-12-13 |
2024-01-17 |
Chugai Pharmaceutical Co Ltd |
SYSTEM FOR DETECTING EXTRACELLULAR PURINERGIC RECEPTOR LIGANDS AND NON-HUMAN ANIMAL INTO WHICH SUCH LIGAND WAS TRANSFERRED
|
US10704033B1
(en)
|
2019-12-13 |
2020-07-07 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
EP3835309A1
(en)
|
2019-12-13 |
2021-06-16 |
KWS SAAT SE & Co. KGaA |
Method for increasing cold or frost tolerance in a plant
|
CN113061626B
(zh)
*
|
2019-12-16 |
2024-01-19 |
中国科学院脑科学与智能技术卓越创新中心 |
一种组织特异性敲除斑马鱼基因的方法及应用
|
KR20220118498A
(ko)
|
2019-12-18 |
2022-08-25 |
인스크립타 인코포레이티드 |
핵산-가이드된 뉴클레아제 편집된 세포의 생체 내 검출을 위한 캐스케이드/dcas3 상보 검정
|
GB201918902D0
(en)
|
2019-12-19 |
2020-02-05 |
Genome Res Ltd |
Cell differentiation
|
US10689669B1
(en)
|
2020-01-11 |
2020-06-23 |
Inscripta, Inc. |
Automated multi-module cell processing methods, instruments, and systems
|
KR20220133257A
(ko)
|
2020-01-27 |
2022-10-04 |
인스크립타 인코포레이티드 |
전기천공 모듈 및 기구
|
EP4096392A1
(en)
|
2020-01-31 |
2022-12-07 |
Calyxt, Inc. |
Increase of saturated fat in soybean
|
US20230070181A1
(en)
|
2020-02-05 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment of cancer disease by targeting an epigenetic factor
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
AU2021226415A1
(en)
|
2020-02-28 |
2022-09-15 |
Pioneer Hi-Bred International, Inc. |
Sorghum doubled haploid production system
|
CA3167369A1
(en)
|
2020-03-04 |
2021-09-10 |
Tara YOUNG |
Methods and compositions for sensitization of tumor cells to immune therapy
|
WO2021183636A1
(en)
|
2020-03-10 |
2021-09-16 |
Calyxt, Inc. |
Transformation and regeneration of cannabaceae
|
JP2023517326A
(ja)
|
2020-03-11 |
2023-04-25 |
オメガ セラピューティクス, インコーポレイテッド |
フォークヘッドボックスp3(foxp3)遺伝子発現をモジュレートするための組成物および方法
|
EP4129050A1
(en)
|
2020-03-26 |
2023-02-08 |
National Agriculture And Food Research Organization |
Method for producing temperature-sensitive male sterile plant
|
WO2021202648A1
(en)
|
2020-03-31 |
2021-10-07 |
Calyxt, Inc. |
Agrobacterium-mediated infiltration of cannabaceae
|
US20230263121A1
(en)
|
2020-03-31 |
2023-08-24 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
EP4132266A2
(en)
|
2020-04-09 |
2023-02-15 |
R. J. Reynolds Tobacco Company |
Methods for modulating the nicotine level in nicotiana tabacum
|
NL2025344B1
(en)
|
2020-04-14 |
2021-10-26 |
Academisch Ziekenhuis Leiden |
Methods for induction of endogenous tandem duplication events
|
US20230165205A1
(en)
|
2020-04-14 |
2023-06-01 |
ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) |
Methods for induction of endogenous tandem duplication events
|
US20210332388A1
(en)
|
2020-04-24 |
2021-10-28 |
Inscripta, Inc. |
Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
|
CA3177093A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
CA3177621A1
(en)
|
2020-05-06 |
2021-11-11 |
Alexandre Juillerat |
Methods to genetically modify cells for delivery of therapeutic proteins
|
EP4146797A1
(en)
|
2020-05-06 |
2023-03-15 |
Orchard Therapeutics (Europe) Limited |
Treatment for neurodegenerative diseases
|
JP2023525304A
(ja)
|
2020-05-08 |
2023-06-15 |
ザ ブロード インスティテュート,インコーポレーテッド |
標的二本鎖ヌクレオチド配列の両鎖同時編集のための方法および組成物
|
WO2021231259A1
(en)
|
2020-05-11 |
2021-11-18 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
US11787841B2
(en)
|
2020-05-19 |
2023-10-17 |
Inscripta, Inc. |
Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
|
WO2021239986A1
(en)
|
2020-05-29 |
2021-12-02 |
KWS SAAT SE & Co. KGaA |
Plant haploid induction
|
WO2021245435A1
(en)
|
2020-06-03 |
2021-12-09 |
Vilmorin & Cie |
Melon plants resistant to scab disease, aphids and powdery mildew
|
BR112022024738A2
(pt)
|
2020-06-05 |
2023-03-07 |
Vilmorin & Cie |
Planta, célula de planta, cultura de tecidos de células, parte de planta, semente, uso de uma planta, métodos para detectar e/ou selecionar plantas, conferir resistência ao tobrfv, melhorar o rendimento de tomateiros e reduzir a perda na produção de tomate e usos de um marcador
|
EP4161552A1
(en)
|
2020-06-05 |
2023-04-12 |
The Broad Institute, Inc. |
Compositions and methods for treating neoplasia
|
US20230305023A1
(en)
|
2020-06-25 |
2023-09-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment and diagnostic of pathological conditions associated with intense stress
|
AR122970A1
(es)
|
2020-07-14 |
2022-10-19 |
Kws Saat Se & Co Kgaa |
Métodos para identificar y seleccionar plantas de maíz con resistencia al tizón de la hoja de maíz del norte
|
AU2021204717A1
(en)
|
2020-07-15 |
2022-02-03 |
Seminis Vegetable Seeds, Inc. |
Green Bean Plants with Improved Disease Resistance
|
AU2021316727A1
(en)
|
2020-07-30 |
2023-03-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immune cells defective for SOCS1
|
EP4192875A1
(en)
|
2020-08-10 |
2023-06-14 |
Precision BioSciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
US20220064596A1
(en)
|
2020-08-25 |
2022-03-03 |
Kite Pharma, Inc. |
T cells with improved functionality
|
US20230265214A1
(en)
|
2020-08-31 |
2023-08-24 |
Yale University |
Compositions and methods for delivery of nucleic acids to cells
|
BR112023003972A2
(pt)
|
2020-09-04 |
2023-04-18 |
Univ Kobe Nat Univ Corp |
Complexos de um módulo de reconhecimento de sequência de ácido nucleico ligado a uma desaminase e de um fragmento amino-terminal de um módulo de reconhecimento de sequência de ácido nucleico, uma desaminase e um fragmento carboxi-terminal de um módulo de reconhecimento de sequência de ácido nucleico ligado ao mesmo, ácido nucleico, vetor, e, método para alterar um sítio alvo de um ácido desoxirribonucleico de fita dupla de uma célula
|
WO2022049273A1
(en)
|
2020-09-07 |
2022-03-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment of inflammatory bowel diseases
|
WO2022060749A1
(en)
|
2020-09-15 |
2022-03-24 |
Inscripta, Inc. |
Crispr editing to embed nucleic acid landing pads into genomes of live cells
|
EP3971295A1
(en)
|
2020-09-16 |
2022-03-23 |
FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. |
Methods for the production of genome edited plants
|
AU2021347907A1
(en)
|
2020-09-23 |
2023-04-20 |
Crispr Therapeutics Ag |
Genetically engineered t cells with regnase-1 and/or tgfbrii disruption have improved functionality and persistence
|
WO2022067130A2
(en)
|
2020-09-24 |
2022-03-31 |
The Broad Institute, Inc. |
Prime editing guide rnas, compositions thereof, and methods of using the same
|
JP2023543614A
(ja)
|
2020-10-02 |
2023-10-17 |
ビルモラン エ コンパニー |
貯蔵寿命が延長されたメロン
|
WO2022076547A1
(en)
|
2020-10-07 |
2022-04-14 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
US20240060079A1
(en)
|
2020-10-23 |
2024-02-22 |
Elo Life Systems |
Methods for producing vanilla plants with improved flavor and agronomic production
|
JPWO2022097663A1
(no)
|
2020-11-06 |
2022-05-12 |
|
|
WO2022096633A1
(en)
|
2020-11-06 |
2022-05-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosis and treating polycystic ovary syndrome (pcos)
|
US11512297B2
(en)
|
2020-11-09 |
2022-11-29 |
Inscripta, Inc. |
Affinity tag for recombination protein recruitment
|
JP2023548979A
(ja)
|
2020-11-10 |
2023-11-21 |
インダストリアル マイクロブス, インコーポレイテッド |
供給原料からポリ(hiba)を産生可能な微生物
|
EP4247151A1
(en)
|
2020-11-20 |
2023-09-27 |
Revivicor Inc. |
Multi-transgenic pigs with growth hormone receptor knockout for xenotransplantation
|
EP4251282A1
(en)
|
2020-11-27 |
2023-10-04 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for diagnosis and monitoring of toxic epidermal necrolysis
|
EP4251746A1
(en)
|
2020-11-30 |
2023-10-04 |
Cellectis SA |
Use of aminoquinoline compounds for higher gene integration
|
IL303269A
(en)
|
2020-12-03 |
2023-07-01 |
Century Therapeutics Inc |
Genetically modified cells and their uses
|
CA3203609A1
(en)
|
2020-12-03 |
2022-06-09 |
Vilmorin & Cie |
Tomato plants resistant to tobrfv, tmv, tomv and tommv and corresponding resistance genes
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
EP4019638A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
EP4019639A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
WO2022137181A1
(en)
|
2020-12-23 |
2022-06-30 |
Crispr Therapeutics Ag |
Co-use of lenalidomide with car-t cells
|
WO2022146654A1
(en)
|
2020-12-28 |
2022-07-07 |
Janssen Pharmaceuticals, Inc. |
Transcription activator-like effector nucleases (talens) targeting hbv
|
EP4271802A1
(en)
|
2021-01-04 |
2023-11-08 |
Inscripta, Inc. |
Mad nucleases
|
US11332742B1
(en)
|
2021-01-07 |
2022-05-17 |
Inscripta, Inc. |
Mad nucleases
|
WO2022150790A2
(en)
|
2021-01-11 |
2022-07-14 |
The Broad Institute, Inc. |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|
CA3207102A1
(en)
|
2021-01-12 |
2022-07-21 |
March Therapeutics, Inc. |
Context-dependent, double-stranded dna-specific deaminases and uses thereof
|
EP4284823A1
(en)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
US11884924B2
(en)
|
2021-02-16 |
2024-01-30 |
Inscripta, Inc. |
Dual strand nucleic acid-guided nickase editing
|
US20220288122A1
(en)
|
2021-03-09 |
2022-09-15 |
Crispr Therapeutics Ag |
Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity
|
EP4304633A1
(en)
|
2021-03-12 |
2024-01-17 |
Mendus B.V. |
Methods of vaccination and use of cd47 blockade
|
WO2022198094A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin in cannabaceae plant parts
|
WO2022198093A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin using plant cell matrices
|
WO2022198107A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalain in cannabaceae plant parts
|
WO2022198085A2
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Plant cell matrices and methods thereof
|
WO2022198106A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalains using plant cell matrices
|
WO2022208489A1
(en)
|
2021-04-02 |
2022-10-06 |
Vilmorin & Cie |
Semi-determinate or determinate growth habit trait in cucurbita
|
KR20230170703A
(ko)
|
2021-04-07 |
2023-12-19 |
센츄리 쎄라퓨틱스 인코포레이티드 |
유도 만능 줄기세포로부터 감마-델타 t 세포의 생성을 위한 조성물 및 방법
|
US20220333074A1
(en)
|
2021-04-07 |
2022-10-20 |
Century Therapeutics, Inc. |
Compositions and Methods for Generating Alpha-Beta T Cells from Induced Pluripotent Stem Cells
|
JP2024513454A
(ja)
|
2021-04-07 |
2024-03-25 |
センチュリー セラピューティクス,インコーポレイテッド |
キメラ抗原受容体細胞のための人工細胞死/リポーター系ポリペプチドの組合せおよびその使用
|
WO2022218998A1
(en)
|
2021-04-13 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for treating hepatitis b and d virus infection
|
WO2022226316A1
(en)
|
2021-04-22 |
2022-10-27 |
Precision Biosciences, Inc. |
Compositions and methods for generating male sterile plants
|
EP4326753A2
(en)
|
2021-04-23 |
2024-02-28 |
University of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas fusion protein and methods of treatment
|
WO2022229412A1
(en)
|
2021-04-30 |
2022-11-03 |
Cellectis S.A. |
New anti-muc1 cars and gene edited immune cells for solid tumors cancer immunotherapy
|
EP4337769A1
(en)
|
2021-05-10 |
2024-03-20 |
SQZ Biotechnologies Company |
Methods for delivering genome editing molecules to the nucleus or cytosol of a cell and uses thereof
|
WO2022251644A1
(en)
|
2021-05-28 |
2022-12-01 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
WO2022256437A1
(en)
|
2021-06-02 |
2022-12-08 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
WO2022271548A2
(en)
|
2021-06-23 |
2022-12-29 |
Massachusetts Institute Of Technology |
Compositions, methods and systems for the delivery of gene editing material to cells
|
CA3225278A1
(en)
|
2021-07-07 |
2023-01-12 |
Robert W. Williams |
Transcription activator-like effectors fused to inteins
|
WO2023283359A2
(en)
|
2021-07-07 |
2023-01-12 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
WO2023006933A1
(en)
|
2021-07-30 |
2023-02-02 |
KWS SAAT SE & Co. KGaA |
Plants with improved digestibility and marker haplotypes
|
IL310564A
(en)
|
2021-08-06 |
2024-03-01 |
Vilmorin & Cie |
Resistance to Leveillula Taurica in pepper plant
|
JP7125727B1
(ja)
|
2021-09-07 |
2022-08-25 |
国立大学法人千葉大学 |
核酸配列改変用組成物および核酸配列の標的部位を改変する方法
|
US20230128917A1
(en)
|
2021-09-14 |
2023-04-27 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having a disrupted cd83 gene
|
CA3232065A1
(en)
|
2021-09-17 |
2023-03-23 |
Cibus Europe B.V. |
Transforming cannabaceae cells
|
AU2022347161A1
(en)
|
2021-09-20 |
2024-04-04 |
Revivicor, Inc. |
Multitransgenic pigs comprising ten genetic modifications for xenotransplantation
|
GB202113933D0
(en)
|
2021-09-29 |
2021-11-10 |
Genome Res Ltd |
Methods for gene editing
|
WO2023064367A1
(en)
|
2021-10-12 |
2023-04-20 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating anti-viral transfer vector igm responses
|
WO2023064924A1
(en)
|
2021-10-14 |
2023-04-20 |
Codiak Biosciences, Inc. |
Modified producer cells for extracellular vesicle production
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
CA3235185A1
(en)
|
2021-10-19 |
2023-04-27 |
Cassandra GORSUCH |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
CA3233935A1
(en)
|
2021-10-20 |
2023-04-27 |
University Of Rochester |
Method for rejuvenating glial progenitor cells and rejuvenated glial progenitor cells per se
|
WO2023070043A1
(en)
|
2021-10-20 |
2023-04-27 |
Yale University |
Compositions and methods for targeted editing and evolution of repetitive genetic elements
|
CA3234634A1
(en)
|
2021-10-20 |
2023-04-27 |
University Of Rochester |
Compositions and methods for treating myelin deficiency by rejuvenating glial progenitor cells
|
WO2023070019A1
(en)
|
2021-10-21 |
2023-04-27 |
Vertex Pharmaceuticals Incorporated |
Hypoimmune cells
|
WO2023081923A1
(en)
|
2021-11-08 |
2023-05-11 |
Frequency Therapeutics, Inc. |
Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
|
US11753677B2
(en)
|
2021-11-10 |
2023-09-12 |
Encodia, Inc. |
Methods for barcoding macromolecules in individual cells
|
WO2023091910A1
(en)
|
2021-11-16 |
2023-05-25 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
WO2023094435A1
(en)
|
2021-11-23 |
2023-06-01 |
Cellectis Sa |
New tale protein scaffolds with improved on-target/off-target activity ratios
|
WO2023093862A1
(en)
|
2021-11-26 |
2023-06-01 |
Epigenic Therapeutics Inc. |
Method of modulating pcsk9 and uses thereof
|
WO2023102393A1
(en)
|
2021-11-30 |
2023-06-08 |
Pioneer Hi-Bred International, Inc. |
High efficiency large scale chromosomal genome manipulation
|
GB202117314D0
(en)
|
2021-11-30 |
2022-01-12 |
Clarke David John |
Cyclic nucleic acid fragmentation
|
WO2023102537A2
(en)
|
2021-12-03 |
2023-06-08 |
The Broad Institute, Inc. |
Self-assembling virus-like particles for delivery of nucleic acid programmable fusion proteins and methods of making and using same
|
WO2023102550A2
(en)
|
2021-12-03 |
2023-06-08 |
The Broad Institute, Inc. |
Compositions and methods for efficient in vivo delivery
|
US20230193310A1
(en)
|
2021-12-10 |
2023-06-22 |
Seminis Vegetabe Seeds, Inc. |
Lettuce plants having resistance to downy mildew
|
GB202118058D0
(en)
|
2021-12-14 |
2022-01-26 |
Univ Warwick |
Methods to increase yields in crops
|
WO2023111913A1
(en)
|
2021-12-15 |
2023-06-22 |
Crispr Therapeutics Ag |
Engineered anti-liv1 cell with regnase-1 and/or tgfbrii disruption
|
WO2023114935A1
(en)
*
|
2021-12-17 |
2023-06-22 |
Altius Institute For Biomedical Sciences |
Nucleic acid sequences encoding repeated sequences resistant to recombination in viruses
|
WO2023119201A2
(en)
|
2021-12-22 |
2023-06-29 |
Crispr Therapeutics Ag |
Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof
|
WO2023126458A1
(en)
|
2021-12-28 |
2023-07-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
WO2023129974A1
(en)
|
2021-12-29 |
2023-07-06 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
WO2023129937A1
(en)
|
2021-12-29 |
2023-07-06 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof
|
WO2023150557A1
(en)
|
2022-02-01 |
2023-08-10 |
University Of Rochester |
Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods
|
WO2023150553A1
(en)
|
2022-02-01 |
2023-08-10 |
University Of Rochester |
Gpr17 promoter-based targeting and transduction of glial progenitor cells
|
WO2023148476A1
(en)
|
2022-02-03 |
2023-08-10 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
WO2023148478A1
(en)
|
2022-02-03 |
2023-08-10 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
WO2023148475A1
(en)
|
2022-02-04 |
2023-08-10 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
WO2023158732A1
(en)
|
2022-02-16 |
2023-08-24 |
Dana-Farber Cancer Institute, Inc. |
Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereof
|
WO2023166425A1
(en)
|
2022-03-01 |
2023-09-07 |
Crispr Therapeutics Ag |
Methods and compositions for treating angiopoietin-like 3 (angptl3) related conditions
|
WO2023172624A1
(en)
|
2022-03-09 |
2023-09-14 |
Selecta Biosciences, Inc. |
Immunosuppressants in combination with anti-igm agents and related dosing
|
US20230293646A1
(en)
|
2022-03-21 |
2023-09-21 |
Crispr Therapeutics Ag |
Methods and compositions for treating lipoprotein-related diseases
|
TW202400778A
(zh)
|
2022-03-23 |
2024-01-01 |
瑞士商Crispr治療公司 |
具有多重基因編輯之抗cd19 car—t細胞及其治療用途
|
US20230331841A1
(en)
|
2022-03-23 |
2023-10-19 |
Crispr Therapeutics Ag |
Anti-cd83 car-t cells with regnase-1 and/or tgfbrii disruption
|
EP4256950A1
(en)
|
2022-04-06 |
2023-10-11 |
Vilmorin et Cie |
Tolerance to cgmmv in cucumber
|
GB202205148D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
GB202205149D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
GB202205562D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
GB202205561D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
GB202206107D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
GB202206109D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
WO2023213831A1
(en)
|
2022-05-02 |
2023-11-09 |
Fondazione Telethon Ets |
Homology independent targeted integration for gene editing
|
WO2023220603A1
(en)
|
2022-05-09 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Vectors and methods for in vivo antibody production
|
WO2023225665A1
(en)
|
2022-05-19 |
2023-11-23 |
Lyell Immunopharma, Inc. |
Polynucleotides targeting nr4a3 and uses thereof
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
EP4278891A1
(en)
|
2022-05-20 |
2023-11-22 |
KWS SAAT SE & Co. KGaA |
Clubroot resistance and markers in brassica
|
GB202207774D0
(en)
|
2022-05-26 |
2022-07-13 |
Cambridge Entpr Ltd |
Modified plants
|
WO2023240147A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells expressing cd16 variants and nkg2d and uses thereof
|
WO2023240212A2
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
|
WO2023240169A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof
|
WO2023242827A2
(en)
|
2022-06-17 |
2023-12-21 |
Crispr Therapeutics Ag |
LIPID NANOPARTICLES (LNPs)-BASED OCULAR DELIVERY
|
WO2023248147A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Methods and compositions for in vivo editing of stem cells
|
WO2023248145A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Compositions and methods for treating human immunodeficiency virus
|
US20230404003A1
(en)
|
2022-06-21 |
2023-12-21 |
Seminis Vegetable Seeds, Inc. |
Novel qtls conferring resistance to cucumber mosaic virus
|
WO2024003786A1
(en)
|
2022-06-29 |
2024-01-04 |
Crispr Therapeutics Ag |
Chimeric antigen receptor targeting gpc-3 and immune cells expressing such for therapeutic uses
|
GB2621813A
(en)
|
2022-06-30 |
2024-02-28 |
Univ Newcastle |
Preventing disease recurrence in Mitochondrial replacement therapy
|
WO2024020360A1
(en)
|
2022-07-18 |
2024-01-25 |
Pairwise Plants Services, Inc. |
Mustard green plants named 'pwrg-1', 'pwrg-2,' and 'pwsgc'
|
WO2024020597A1
(en)
|
2022-07-22 |
2024-01-25 |
The Johns Hopkins University |
Dendrimer-enabled targeted intracellular crispr/cas system delivery and gene editing
|
WO2024026474A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle
|
WO2024023804A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene
|
WO2024023802A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene
|
WO2024023801A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene
|
LU502613B1
(en)
|
2022-08-01 |
2024-02-01 |
Plant Bioscience Ltd |
Methods of altering the starch granule profile in plants
|
WO2024031053A1
(en)
|
2022-08-05 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
Aggregation-resistant variants of tdp-43
|
WO2024042199A1
(en)
|
2022-08-26 |
2024-02-29 |
KWS SAAT SE & Co. KGaA |
Use of paired genes in hybrid breeding
|
WO2024062388A2
(en)
|
2022-09-20 |
2024-03-28 |
Crispr Therapeutics Ag |
Genetically engineered immune cells expressing chimeric antigen receptor targeting cd20
|
WO2024064958A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
WO2024064952A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells overexpressing c-jun
|
GB202214410D0
(en)
|
2022-09-30 |
2022-11-16 |
Ivy Farm Tech Limited |
genetically modified cells
|
WO2024077174A1
(en)
|
2022-10-05 |
2024-04-11 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
WO2024081736A2
(en)
|
2022-10-11 |
2024-04-18 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
WO2024079157A1
(en)
|
2022-10-11 |
2024-04-18 |
KWS SAAT SE & Co. KGaA |
Virus and insect resistance and markers in barley
|