MX363017B - Métodos y productos para la expresión de proteínas en células. - Google Patents

Métodos y productos para la expresión de proteínas en células.

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Publication number
MX363017B
MX363017B MX2015005346A MX2015005346A MX363017B MX 363017 B MX363017 B MX 363017B MX 2015005346 A MX2015005346 A MX 2015005346A MX 2015005346 A MX2015005346 A MX 2015005346A MX 363017 B MX363017 B MX 363017B
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MX
Mexico
Prior art keywords
methods
cells
products
proteins
nucleic acids
Prior art date
Application number
MX2015005346A
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English (en)
Other versions
MX2015005346A (es
Inventor
Angel Matthew
Rohde Christopher
Original Assignee
Factor Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Factor Bioscience Inc filed Critical Factor Bioscience Inc
Publication of MX2015005346A publication Critical patent/MX2015005346A/es
Publication of MX363017B publication Critical patent/MX363017B/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

La presente invención se refiere a una composición caracterizada porque comprende un ácido nucleico que codifica una proteína de edición de genes que comprende: (a) un dominio de unión al ADN y (b) un dominio de nucleasa, en donde: (a) el dominio de unión al ADN comprende una pluralidad de secuencias de repetición yu al menos una de las secuencias de repetición comprende la secuencia de aminoácidos (SEQ ID NO: 75) y tiene una longitud de entre 36 y 39 aminoácidos, en donde "v" es E, "w" es S, "x" es N, "y" es I o S, y "z" (SEQ ID NO: 671); y (b) el dominio de nucleasa comprende un dominio catalítico de una nucleasa.
MX2015005346A 2012-11-01 2013-11-01 Métodos y productos para la expresión de proteínas en células. MX363017B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261721302P 2012-11-01 2012-11-01
US201361785404P 2013-03-14 2013-03-14
US201361842874P 2013-07-03 2013-07-03
PCT/US2013/068118 WO2014071219A1 (en) 2012-11-01 2013-11-01 Methods and products for expressing proteins in cells

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MX2015005346A MX2015005346A (es) 2015-07-14
MX363017B true MX363017B (es) 2019-03-04

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MX2019002498A MX2019002498A (es) 2012-11-01 2015-04-27 Metodos y productos para la expresion de proteinas en celulas.

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US (19) US9447395B2 (es)
EP (2) EP2914728B1 (es)
JP (5) JP6510416B2 (es)
KR (4) KR102596302B1 (es)
CN (1) CN104769112A (es)
AU (3) AU2013337651B2 (es)
BR (2) BR122019025678B1 (es)
CA (2) CA3150985A1 (es)
HK (1) HK1214304A1 (es)
MX (2) MX363017B (es)
RU (2) RU2711249C2 (es)
WO (1) WO2014071219A1 (es)

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