SG10201809564YA - Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof - Google Patents

Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof

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Publication number
SG10201809564YA
SG10201809564YA SG10201809564YA SG10201809564YA SG10201809564YA SG 10201809564Y A SG10201809564Y A SG 10201809564YA SG 10201809564Y A SG10201809564Y A SG 10201809564YA SG 10201809564Y A SG10201809564Y A SG 10201809564YA SG 10201809564Y A SG10201809564Y A SG 10201809564YA
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Singapore
Prior art keywords
target dna
cas protein
cleaving
nucleic acid
composition
Prior art date
Application number
SG10201809564YA
Inventor
Jin-Soo Kim
Seung Woo Cho
Sojung Kim
Jong Min Kim
Seokjoong Kim
Original Assignee
Toolgen Inc
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50544909&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201809564Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Toolgen Inc filed Critical Toolgen Inc
Publication of SG10201809564YA publication Critical patent/SG10201809564YA/en

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6813—Hybridisation assays
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin

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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract

【 】 COMPOSITION FOR CLEAVING A TARGET DNA COMPRISING A GUIDE RNA SPECIFIC FOR THE TARGET DNA AND CAS PROTEIN-ENCODING NUCLEIC ACID OR CAS PROTEIN, AND USE THEREOF The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof. Fig. 1a
SG10201809564YA 2012-10-23 2013-10-23 Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof SG10201809564YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261717324P 2012-10-23 2012-10-23
US201361803599P 2013-03-20 2013-03-20
US201361837481P 2013-06-20 2013-06-20

Publications (1)

Publication Number Publication Date
SG10201809564YA true SG10201809564YA (en) 2018-11-29

Family

ID=50544909

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SG10201809566SA SG10201809566SA (en) 2012-10-23 2013-10-23 Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
SG10201809564YA SG10201809564YA (en) 2012-10-23 2013-10-23 Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
SG11201503059XA SG11201503059XA (en) 2012-10-23 2013-10-23 Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof

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SG10201809566SA SG10201809566SA (en) 2012-10-23 2013-10-23 Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof

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Country Status (16)

Country Link
US (9) US20150284727A1 (en)
EP (7) EP4180526A3 (en)
JP (7) JP6517143B2 (en)
KR (5) KR102052286B1 (en)
CN (9) CN110669746B (en)
AU (5) AU2013335451B2 (en)
BR (1) BR112015008708A2 (en)
CA (2) CA3233048A1 (en)
DE (2) DE202013012597U1 (en)
DK (1) DK2912175T3 (en)
ES (3) ES2926021T3 (en)
HK (4) HK1212732A1 (en)
PL (1) PL2912175T3 (en)
PT (1) PT2912175T (en)
SG (3) SG10201809566SA (en)
WO (1) WO2014065596A1 (en)

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