|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
|
US20130266551A1
(en)
*
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
|
PL3246416T3
(pl)
|
2011-04-15 |
2024-09-30 |
The Johns Hopkins University |
Bezpieczny system sekwencjonowania
|
|
MX2014010183A
(es)
|
2012-02-22 |
2015-03-20 |
Univ Pennsylvania |
Composiciones y metodos para generar una poblacion persistente de celulas t utiles para el tratamiento de cancer.
|
|
CN109457030B
(zh)
|
2012-10-29 |
2022-02-18 |
约翰·霍普金斯大学 |
卵巢和子宫内膜癌的帕帕尼科拉乌测试
|
|
EP3653212B1
(en)
|
2012-12-20 |
2023-04-26 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
ES2814962T3
(es)
|
2013-02-20 |
2021-03-29 |
Novartis Ag |
Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123
|
|
PL2958943T3
(pl)
|
2013-02-20 |
2020-04-30 |
The Trustees Of The University Of Pennsylvania |
Leczenie nowotworu złośliwego za pomocą humanizowanego chimerycznego receptora antygenowego anty-egfrviii
|
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
|
ES3058841T3
(en)
|
2013-03-15 |
2026-03-13 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
|
CA2931684C
(en)
|
2013-12-19 |
2024-02-20 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
EP4420663A3
(en)
|
2013-12-20 |
2024-10-30 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
EP3808410A1
(en)
|
2013-12-20 |
2021-04-21 |
Cellectis |
Method of engineering multi-input signal sensitive t cell for immunotherapy
|
|
CN107074957B
(zh)
|
2014-01-13 |
2021-05-07 |
希望之城公司 |
在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法
|
|
EP4303229A3
(en)
|
2014-01-21 |
2024-04-17 |
Novartis AG |
Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
|
|
US10189908B2
(en)
|
2014-02-05 |
2019-01-29 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-specific TN glycopeptide variants
|
|
EP3105333B1
(en)
|
2014-02-10 |
2020-04-08 |
Emory University |
Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer
|
|
CA2943008C
(en)
*
|
2014-03-19 |
2021-03-30 |
Cellectis |
Cd123 specific chimeric antigen receptors for cancer immunotherapy
|
|
SI3888674T1
(sl)
*
|
2014-04-07 |
2024-08-30 |
Novartis Ag |
Zdravljenje raka z uporabo antigenskega himernega receptorja proti-CD19
|
|
CN112877291A
(zh)
|
2014-04-10 |
2021-06-01 |
西雅图儿童医院 (Dba西雅图儿童研究所) |
基因修饰的t细胞产品、其制备方法和用途
|
|
CA2947429A1
(en)
|
2014-05-02 |
2015-11-05 |
Emory University |
Humanized variable lymphocyte receptors (vlr) and compositions and uses related thereto
|
|
KR20210014210A
(ko)
|
2014-05-15 |
2021-02-08 |
내셔널 유니버시티 오브 싱가포르 |
변형된 천연 살해 세포 및 그의 용도
|
|
EP3149044B1
(en)
|
2014-06-02 |
2020-10-21 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Chimeric antigen receptors targeting cd-19
|
|
WO2016011210A2
(en)
|
2014-07-15 |
2016-01-21 |
Juno Therapeutics, Inc. |
Engineered cells for adoptive cell therapy
|
|
JP6736540B2
(ja)
|
2014-07-21 |
2020-08-05 |
ノバルティス アーゲー |
Cll−1キメラ抗原受容体を使用した癌の処置
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
US10174095B2
(en)
|
2014-07-21 |
2019-01-08 |
Novartis Ag |
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
|
|
SG10201913765YA
(en)
|
2014-07-21 |
2020-03-30 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
MX2017001079A
(es)
|
2014-07-24 |
2017-09-12 |
Bluebird Bio Inc |
Receptores de antígeno quiméricos de antígeno de maduración de células b (bcma).
|
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
|
RU2020117196A
(ru)
|
2014-08-19 |
2020-10-15 |
Новартис Аг |
Химерный антигенный рецептор (car) против cd123 для использования в лечении злокачественных опухолей
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
JP6839074B2
(ja)
|
2014-09-17 |
2021-03-03 |
ノバルティス アーゲー |
養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング
|
|
MX2017004603A
(es)
*
|
2014-10-07 |
2017-06-30 |
Cellectis |
Metodo para modular actividad de celulas inmunes inducidas por car.
|
|
CA2963935A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
WO2016061368A1
(en)
*
|
2014-10-15 |
2016-04-21 |
The Children's Hospital Of Philadelphia |
Compositions and methods for treating b-lymphoid malignancies
|
|
EP3209690B1
(en)
|
2014-10-20 |
2021-05-05 |
Juno Therapeutics, Inc. |
Methods and compositions for dosing in adoptive cell therapy
|
|
KR102357004B1
(ko)
*
|
2014-10-27 |
2022-01-27 |
프레드 헛친슨 켄서 리서치 센터 |
입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법
|
|
HK1243333A1
(zh)
*
|
2014-10-31 |
2018-07-13 |
The Trustees Of The University Of Pennsylvania |
用於修饰的t细胞的方法和组合物
|
|
WO2016073602A2
(en)
*
|
2014-11-05 |
2016-05-12 |
Juno Therapeutics, Inc. |
Methods for transduction and cell processing
|
|
US20180334490A1
(en)
*
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
EP3227323B1
(en)
|
2014-12-03 |
2020-08-05 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
SMT201900596T1
(it)
|
2014-12-12 |
2019-11-13 |
Bluebird Bio Inc |
Recettori chimerici di antigene per bcma
|
|
EP3233095A2
(en)
*
|
2014-12-17 |
2017-10-25 |
Cellectis |
INHIBITORY CHIMERIC ANTIGEN RECEPTOR (iCAR OR N-CAR) EXPRESSING NON-T CELL TRANSDUCTION DOMAIN
|
|
IL253149B2
(en)
*
|
2014-12-29 |
2023-11-01 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US11382963B2
(en)
|
2015-01-12 |
2022-07-12 |
Pieris Pharmaceuticals Gmbh |
Engineered T cells and uses therefor
|
|
WO2016115482A1
(en)
|
2015-01-16 |
2016-07-21 |
Novartis Pharma Ag |
Phosphoglycerate kinase 1 (pgk) promoters and methods of use for expressing chimeric antigen receptor
|
|
GB201501004D0
(en)
|
2015-01-21 |
2015-03-04 |
Cancer Rec Tech Ltd |
Inhibitors
|
|
US20180002435A1
(en)
|
2015-01-26 |
2018-01-04 |
Cellectis |
mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS
|
|
JP7264592B2
(ja)
|
2015-01-26 |
2023-04-25 |
ザ ユニバーシティー オブ シカゴ |
IL13Rα2結合剤及び癌治療におけるその使用
|
|
WO2016123143A1
(en)
|
2015-01-26 |
2016-08-04 |
The University Of Chicago |
CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Rα2
|
|
CA2975384A1
(en)
*
|
2015-01-29 |
2016-08-04 |
Regents Of The University Of Minnesota |
Chimeric antigen receptors, compositions, and methods
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
WO2016149485A1
(en)
*
|
2015-03-17 |
2016-09-22 |
The Regents Of The University Of California |
Novel chemoimmunotherapy for epithelial cancer
|
|
EP3280795B1
(en)
|
2015-04-07 |
2021-03-24 |
Novartis AG |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
|
IL303972A
(en)
*
|
2015-04-08 |
2023-08-01 |
Novartis Ag |
CD20 treatments, CD22 treatments and combined treatments with CD19 chimeric antigen receptor expressing cell
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
GB201507111D0
(en)
*
|
2015-04-27 |
2015-06-10 |
Ucl Business Plc |
Nucleic acid construct
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
JP7340221B2
(ja)
|
2015-05-01 |
2023-09-07 |
ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア |
グリカン依存性免疫療法分子
|
|
MX2017014822A
(es)
|
2015-05-18 |
2018-04-30 |
Tcr2 Therapeutics Inc |
Composiciones y métodos para la reprogramación del tcr con proteínas de fusión.
|
|
ES2889906T3
(es)
|
2015-05-21 |
2022-01-14 |
Harpoon Therapeutics Inc |
Proteínas de unión triespecíficas y usos médicos
|
|
EP4218778A3
(en)
|
2015-05-28 |
2023-08-23 |
Kite Pharma, Inc. |
Diagnostic methods for t cell therapy
|
|
WO2016196384A1
(en)
|
2015-05-29 |
2016-12-08 |
Fred Hutchinson Cancer Research Center |
Compositions for cellular immunotherapy
|
|
CN108603170A
(zh)
|
2015-06-12 |
2018-09-28 |
莱蒂恩技术公司 |
用工程改造的t细胞治疗癌症的方法
|
|
FI3909972T3
(fi)
|
2015-06-19 |
2024-05-03 |
Sebastian Kobold |
Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä
|
|
JP2018518978A
(ja)
*
|
2015-07-08 |
2018-07-19 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
キメラ抗原受容体(car)療法のためのt細胞の供給源としての骨髄浸潤リンパ球(mil)
|
|
JP7245647B2
(ja)
|
2015-07-15 |
2023-03-24 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法用の操作された細胞
|
|
CN107921087A
(zh)
|
2015-07-16 |
2018-04-17 |
百欧肯治疗有限公司 |
治疗癌症的组合物及方法
|
|
AU2016297014B2
(en)
|
2015-07-21 |
2021-06-17 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
US10493139B2
(en)
|
2015-07-24 |
2019-12-03 |
Innovative Cellular Therapeutics CO., LTD. |
Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
|
|
EP3149046B1
(en)
*
|
2015-07-24 |
2020-02-26 |
Innovative Cellular Therapeutics Co., Ltd. |
Humanized anti-cd19 antibody and use thereof
|
|
HK1256087A1
(zh)
*
|
2015-08-07 |
2019-09-13 |
Seattle Children's Hospital, Dba Seattle Children's Research Institute |
用於实体瘤靶向的双特异性cart细胞
|
|
US11667691B2
(en)
|
2015-08-07 |
2023-06-06 |
Novartis Ag |
Treatment of cancer using chimeric CD3 receptor proteins
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
US11286531B2
(en)
|
2015-08-11 |
2022-03-29 |
The Johns Hopkins University |
Assaying ovarian cyst fluid
|
|
WO2017027843A1
(en)
|
2015-08-12 |
2017-02-16 |
Massachusetts Institute Of Technology |
Cell surface coupling of nanoparticles
|
|
CN106467906B
(zh)
*
|
2015-08-20 |
2019-09-27 |
北京马力喏生物科技有限公司 |
构建体、转基因淋巴细胞及其制备方法和用途
|
|
WO2017035117A1
(en)
*
|
2015-08-24 |
2017-03-02 |
University Of Houston System |
Combination therpay combining car + t cells with appropriately timed immunodulatory antibodies
|
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
|
HUE066644T2
(hu)
*
|
2015-09-15 |
2024-08-28 |
Acerta Pharma Bv |
CD19-inhibitor és BTK-inhibitor terápiás kombinációi
|
|
US10265379B2
(en)
*
|
2015-09-16 |
2019-04-23 |
Annabelle Rodriguez Oquendo |
Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for cardiovascular disease and other chronic inflammatory diseases
|
|
WO2017053556A1
(en)
|
2015-09-22 |
2017-03-30 |
The Trustees Of The University Of Pennsylvania |
Method of redirecting t cells to treat hiv infection
|
|
KR20180053744A
(ko)
*
|
2015-09-23 |
2018-05-23 |
사이토이뮨 테라퓨틱스 엘엘씨 |
면역 요법을 위한 flt3 유도된 car 세포
|
|
EP3355937A4
(en)
*
|
2015-09-28 |
2019-04-17 |
Regents of the University of Minnesota |
CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS AS THERAPEUTIC INTERVENTIONS AT AUTO AND ALLO IMMUNITY
|
|
WO2017062820A1
(en)
*
|
2015-10-09 |
2017-04-13 |
Miltenyi Biotec Technology, Inc. |
Chimeric antigen receptors and methods of use
|
|
ES2902987T3
(es)
*
|
2015-10-13 |
2022-03-30 |
Hope City |
Receptores de antígeno quiméricos que contienen un dominio de clorotoxina
|
|
MX2018004515A
(es)
|
2015-10-13 |
2019-04-15 |
Eureka Therapeutics Inc |
Agentes de anticuerpo especificos para cd19 humano y usos de los mismos.
|
|
DK3362569T3
(da)
|
2015-10-16 |
2021-10-18 |
Univ Muenchen Ludwig Maximilians |
Cxcr6-transducerede t-celler til målrettet tumorterapi
|
|
WO2017066583A1
(en)
*
|
2015-10-16 |
2017-04-20 |
University Of Utah Research Foundation |
A nanomaterial complex comprising graphene oxide associated with a therapeutic agent and methods of use
|
|
MX2018005618A
(es)
|
2015-11-05 |
2018-08-01 |
Juno Therapeutics Inc |
Receptores quimericos que contienen dominios inductores de traf y composiciones y metodos relacionados.
|
|
US11020429B2
(en)
|
2015-11-05 |
2021-06-01 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
|
CN105331585A
(zh)
|
2015-11-13 |
2016-02-17 |
科济生物医药(上海)有限公司 |
携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞
|
|
SG11201804178YA
(en)
|
2015-11-18 |
2018-06-28 |
Merck Sharp & Dohme |
Pd1 and/or lag3 binders
|
|
AU2016363025B2
(en)
|
2015-12-03 |
2021-04-08 |
Juno Therapeutics, Inc. |
Modified chimeric receptors and related compositions and methods
|
|
EP4212166A1
(en)
*
|
2015-12-03 |
2023-07-19 |
Juno Therapeutics, Inc. |
Compositions and methods for reducing immune responses against cell therapies
|
|
IL259576B
(en)
|
2015-12-04 |
2022-09-01 |
Novartis Ag |
grna molecule containing tracr and crrna, pharmaceutical composition containing it and method for preparing cells for immunotherapy
|
|
EP3384294B1
(en)
|
2015-12-04 |
2021-10-13 |
Juno Therapeutics, Inc. |
Methods and compositions related to toxicity associated with cell therapy
|
|
US11413340B2
(en)
|
2015-12-22 |
2022-08-16 |
Novartis Ag |
Mesothelin chimeric antigen receptor (CAR) and antibody against PD-L1 inhibitor for combined use in anticancer therapy
|
|
AU2016380262B2
(en)
|
2015-12-28 |
2023-02-09 |
Novartis Ag |
Methods of making chimeric antigen receptor -expressing cells
|
|
CN109072195A
(zh)
|
2015-12-30 |
2018-12-21 |
诺华股份有限公司 |
具有增强功效的免疫效应细胞疗法
|
|
JP7012645B2
(ja)
|
2016-01-11 |
2022-01-28 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
キメラタンパク質および免疫治療の方法
|
|
MX2018008344A
(es)
|
2016-01-11 |
2018-12-06 |
Univ Leland Stanford Junior |
Proteinas quimericas y metodos para regular la expresion genica.
|
|
CN105950645A
(zh)
*
|
2016-01-11 |
2016-09-21 |
灏灵赛奥(天津)生物科技有限公司 |
Car-cd19抗原受体的人源化融合基因片段、其构建方法及应用
|
|
CN107034193B
(zh)
*
|
2016-02-03 |
2020-06-05 |
北京马力喏生物科技有限公司 |
治疗b细胞白血病及b细胞淋巴瘤的治疗组合物
|
|
WO2017149515A1
(en)
*
|
2016-03-04 |
2017-09-08 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
US20190287013A1
(en)
|
2016-03-16 |
2019-09-19 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
|
WO2017161212A1
(en)
|
2016-03-16 |
2017-09-21 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
|
KR102499191B1
(ko)
|
2016-03-18 |
2023-02-13 |
프레드 허친슨 캔서 센터 |
Cd20 면역요법을 위한 조성물 및 방법
|
|
US11111505B2
(en)
|
2016-03-19 |
2021-09-07 |
Exuma Biotech, Corp. |
Methods and compositions for transducing lymphocytes and regulating the activity thereof
|
|
US11325948B2
(en)
|
2016-03-19 |
2022-05-10 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
|
|
MA44486A
(fr)
|
2016-03-22 |
2019-01-30 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Procédés d'intervention précoce pour prévenir ou atténuer la toxicité
|
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
AU2017236069B2
(en)
|
2016-03-23 |
2021-04-08 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins of PD-1 and 4-1BB
|
|
JP7208010B2
(ja)
*
|
2016-03-29 |
2023-01-18 |
ユニバーシティ オブ サザン カリフォルニア |
癌を標的とするキメラ抗原受容体
|
|
CN109069537B
(zh)
*
|
2016-04-04 |
2022-04-15 |
亘喜生物科技(上海)有限公司 |
共刺激结构域中具有重复结合基序的car
|
|
EP3439675A4
(en)
|
2016-04-08 |
2019-12-18 |
Purdue Research Foundation |
METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
|
|
WO2017180587A2
(en)
|
2016-04-11 |
2017-10-19 |
Obsidian Therapeutics, Inc. |
Regulated biocircuit systems
|
|
CN109715808A
(zh)
|
2016-04-15 |
2019-05-03 |
诺华股份有限公司 |
用于选择性蛋白质表达的组合物和方法
|
|
JP7033549B2
(ja)
|
2016-05-04 |
2022-03-10 |
フレッド ハッチンソン キャンサー リサーチ センター |
細胞に基づくネオ抗原ワクチンおよびその使用
|
|
CN105950662B
(zh)
*
|
2016-05-17 |
2019-04-30 |
上海优卡迪生物医药科技有限公司 |
一种靶向cd22的复制缺陷性重组慢病毒car-t转基因载体及其构建方法和应用
|
|
CN105950664B
(zh)
*
|
2016-05-17 |
2019-03-29 |
上海优卡迪生物医药科技有限公司 |
一种靶向cd123的复制缺陷性重组慢病毒car-t转基因载体及其构建方法和应用
|
|
CN105969805B
(zh)
*
|
2016-05-17 |
2019-03-29 |
上海优卡迪生物医药科技有限公司 |
一种靶向Mesothelin的复制缺陷性重组慢病毒CAR-T转基因载体及其构建方法和应用
|
|
CN105950663B
(zh)
*
|
2016-05-17 |
2019-04-02 |
上海优卡迪生物医药科技有限公司 |
一种靶向cd30的复制缺陷性重组慢病毒car-t转基因载体及其构建方法和应用
|
|
CA3024723A1
(en)
|
2016-05-20 |
2017-11-23 |
Robert B. Dubridge |
Single domain serum albumin binding protein
|
|
EP3464375A2
(en)
|
2016-06-02 |
2019-04-10 |
Novartis AG |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
CN109562127A
(zh)
|
2016-06-03 |
2019-04-02 |
纪念斯隆-凯特琳癌症中心 |
作为早期治疗选择的过继细胞疗法
|
|
KR20240036704A
(ko)
|
2016-06-06 |
2024-03-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 치료법을 이용한 b 세포 악성종양의 치료 방법
|
|
KR20230110373A
(ko)
*
|
2016-06-14 |
2023-07-21 |
리전츠 오브 더 유니버스티 오브 미네소타 |
질환을 치료하기 위한 유전적으로 변형된 세포, 조직,및 장기
|
|
CN107523549A
(zh)
*
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达激活型抗体的car‑t细胞及其用途
|
|
CN107523548A
(zh)
*
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抗体的t细胞及其用途
|
|
CN106117366A
(zh)
*
|
2016-06-24 |
2016-11-16 |
安徽未名细胞治疗有限公司 |
一种cd19特异性嵌合抗原受体及其编码基因、应用
|
|
MA45455A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Procédé d'identification d'épitopes peptidiques, molécules qui se lient à de tels épitopes et utilisations associées
|
|
US20190324030A1
(en)
|
2016-06-27 |
2019-10-24 |
Juno Therapeutics, Inc. |
Mhc-e restricted epitopes, binding molecules and related methods and uses
|
|
MX2018015414A
(es)
|
2016-06-30 |
2019-08-01 |
Hoffmann La Roche |
Terapia de célula t adoptiva mejorada.
|
|
CN106267409B
(zh)
*
|
2016-07-01 |
2019-02-01 |
翁炳焕 |
艾滋病生物治疗反应器
|
|
CN106178163B
(zh)
*
|
2016-07-01 |
2019-02-01 |
翁炳焕 |
艾滋病生物细胞免疫治疗仪
|
|
CN107586341A
(zh)
*
|
2016-07-08 |
2018-01-16 |
生命序有限公司 |
重组免疫检查点受体及免疫检查点抑制分子的共表达及应用
|
|
CN107586342A
(zh)
*
|
2016-07-08 |
2018-01-16 |
生命序有限公司 |
重组免疫检查点受体及其应用
|
|
US20190336504A1
(en)
|
2016-07-15 |
2019-11-07 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
CN116769050A
(zh)
|
2016-07-20 |
2023-09-19 |
犹他大学研究基金会 |
Cd229 car t细胞及其使用方法
|
|
CN106011174B
(zh)
*
|
2016-07-26 |
2019-12-13 |
天晴干细胞股份有限公司 |
一种通用型慢病毒载体及其制备方法
|
|
KR20230100748A
(ko)
|
2016-07-28 |
2023-07-05 |
노파르티스 아게 |
키메라 항원 수용체 및 pd-1 억제제의 조합 요법
|
|
MA45784A
(fr)
|
2016-07-29 |
2019-06-05 |
Juno Therapeutics Inc |
Anticorps anti-idiotypes dirigés contre anti-cd19 anticorps
|
|
CN110267677A
(zh)
|
2016-08-01 |
2019-09-20 |
诺华股份有限公司 |
使用与原m2巨噬细胞分子抑制剂组合的嵌合抗原受体治疗癌症
|
|
CA3032498A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CN106399242B
(zh)
*
|
2016-09-13 |
2019-01-22 |
北京多赢时代转化医学研究院 |
联合制备CAR-Vγ9Vδ2T细胞和CAR-NKT细胞的方法
|
|
CN106350487B
(zh)
*
|
2016-09-13 |
2019-01-25 |
北京多赢时代转化医学研究院 |
联合制备car-nk细胞和car-nkt细胞的方法
|
|
EP3515475B1
(en)
|
2016-09-21 |
2024-05-01 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Chimeric antigen receptor (car) that targets chemokine receptor ccr4 and its use
|
|
EP3518943A4
(en)
|
2016-09-28 |
2020-04-22 |
Atossa Therapeutics, Inc. |
METHOD FOR ADAPTIVE CELL THERAPY
|
|
US20190203230A1
(en)
|
2016-09-28 |
2019-07-04 |
Novartis Ag |
Porous membrane-based macromolecule delivery system
|
|
CN106317228A
(zh)
*
|
2016-09-28 |
2017-01-11 |
李华顺 |
一种嵌合抗原受体分子及其应用
|
|
US11155832B2
(en)
|
2016-09-30 |
2021-10-26 |
Genvec, Inc. |
Adenovectors for delivery of therapeutic genetic material into T cells
|
|
MX2019003899A
(es)
|
2016-10-07 |
2019-08-14 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
|
|
MY200337A
(en)
|
2016-10-07 |
2023-12-20 |
Novartis Ag |
Nucleic acid molecules encoding chimeric antigen receptors comprising a cd20 binding domain
|
|
WO2018071873A2
(en)
|
2016-10-13 |
2018-04-19 |
Juno Therapeutics, Inc. |
Immunotherapy methods and compositions involving tryptophan metabolic pathway modulators
|
|
CN107988164B
(zh)
|
2016-10-26 |
2020-07-07 |
阿思科力(苏州)生物科技有限公司 |
一种pd-1 car nk-92细胞及其制备方法与应用
|
|
US20190292246A1
(en)
|
2016-11-03 |
2019-09-26 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia imhibitor
|
|
US20190298772A1
(en)
|
2016-11-03 |
2019-10-03 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell-based therapy and a btk inhibitor
|
|
BR112019009099A2
(pt)
|
2016-11-04 |
2019-07-16 |
Bluebird Bio Inc |
composições de células t car anti-bcma
|
|
EP3544996A2
(en)
|
2016-11-22 |
2019-10-02 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
FI3548515T3
(fi)
|
2016-12-01 |
2026-03-04 |
Regeneron Pharma |
Radioleimattuja anti-PD-L1-vasta-aineita immuno-PET-kuvantamiseen
|
|
CN110494565A
(zh)
|
2016-12-02 |
2019-11-22 |
朱诺治疗学股份有限公司 |
工程化b细胞及相关组合物和方法
|
|
WO2018102795A2
(en)
|
2016-12-02 |
2018-06-07 |
University Of Southern California |
Synthetic immune receptors and methods of use thereof
|
|
EP3548046A2
(en)
|
2016-12-03 |
2019-10-09 |
Juno Therapeutics, Inc. |
Methods and compositions for use of therapeutic t cells in combination with kinase inhibitors
|
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
JP7227131B2
(ja)
|
2016-12-03 |
2023-02-21 |
ジュノー セラピューティクス インコーポレイテッド |
Car-t細胞の投薬を決定するための方法
|
|
US11408005B2
(en)
|
2016-12-12 |
2022-08-09 |
Seattle Children's Hospital |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
|
|
CN108610420B
(zh)
*
|
2016-12-13 |
2023-09-26 |
科济生物医药(上海)有限公司 |
抗cd19的人源化抗体以及靶向cd19的免疫效应细胞
|
|
CN108250301A
(zh)
|
2016-12-29 |
2018-07-06 |
天津天锐生物科技有限公司 |
一种多靶点嵌合抗原受体
|
|
EP4032550A3
(en)
*
|
2017-01-05 |
2022-10-19 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
|
|
EP3346001A1
(en)
*
|
2017-01-06 |
2018-07-11 |
TXCell |
Monospecific regulatory t cell population with cytotoxicity for b cells
|
|
JP7429338B2
(ja)
|
2017-01-10 |
2024-02-08 |
ジュノー セラピューティクス インコーポレイテッド |
細胞療法および関連方法のエピジェネティック解析
|
|
CA3048648A1
(en)
*
|
2017-01-10 |
2018-07-19 |
The General Hospital Corporation |
T cells expressing a chimeric antigen receptor
|
|
CN107058390A
(zh)
*
|
2017-01-17 |
2017-08-18 |
上海交通大学医学院附属第九人民医院 |
一种慢病毒载体、重组慢病毒质粒、病毒及病毒的应用
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
EP3577134A1
(en)
|
2017-01-31 |
2019-12-11 |
Novartis AG |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
|
CN110461335A
(zh)
|
2017-02-17 |
2019-11-15 |
弗雷德哈钦森癌症研究中心 |
用于治疗bcma相关癌症和自身免疫性失调的联合疗法
|
|
ES2988795T3
(es)
|
2017-02-27 |
2024-11-21 |
Juno Therapeutics Inc |
Composiciones, artículos de fabricación y métodos relacionados con la dosificación en terapia celular
|
|
ES3010559T3
(en)
|
2017-02-28 |
2025-04-03 |
Endocyte Inc |
Compositions and methods for car t cell therapy
|
|
US20200048359A1
(en)
|
2017-02-28 |
2020-02-13 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
JP7359751B2
(ja)
|
2017-03-14 |
2023-10-11 |
ジュノー セラピューティクス インコーポレイテッド |
極低温保管のための方法
|
|
CA3054621A1
(en)
|
2017-03-22 |
2018-09-27 |
Novartis Ag |
Compositions and methods for immunooncology
|
|
AU2018245749A1
(en)
|
2017-03-27 |
2019-10-03 |
National University Of Singapore |
Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
|
|
CA3056439A1
(en)
|
2017-03-27 |
2018-10-04 |
National University Of Singapore |
Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
CN107058232B
(zh)
*
|
2017-04-12 |
2018-03-30 |
上海优卡迪生物医药科技有限公司 |
胆固醇转脂酶soat1被抑制的car‑t细胞及其制备方法和应用
|
|
CN110709700A
(zh)
|
2017-04-14 |
2020-01-17 |
朱诺治疗学股份有限公司 |
评估细胞表面糖基化的方法
|
|
CN108728459B
(zh)
*
|
2017-04-24 |
2023-08-04 |
上海恒润达生生物科技股份有限公司 |
靶向cd19的嵌合抗原受体并联合表达il-15的方法和用途
|
|
JOP20180042A1
(ar)
*
|
2017-04-24 |
2019-01-30 |
Kite Pharma Inc |
نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
CA3061945A1
(en)
|
2017-05-01 |
2018-11-08 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
|
CN110891567B
(zh)
|
2017-05-24 |
2024-01-09 |
效应治疗股份有限公司 |
用于改善的抗肿瘤免疫应答的组合物和方法
|
|
KR20200054160A
(ko)
|
2017-06-02 |
2020-05-19 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 요법을 사용한 치료를 위한 물품 제조 및 방법
|
|
CN108977453A
(zh)
|
2017-06-02 |
2018-12-11 |
阿思科力(苏州)生物科技有限公司 |
一种以robo1为靶点的嵌合抗原受体细胞及其制备和应用
|
|
CA3061959A1
(en)
|
2017-06-09 |
2018-12-13 |
Providence Health & Services - Oregon |
Utilization of cd39 and cd103 for identification of human tumor reactive t cells for treatment of cancer
|
|
US11241485B2
(en)
|
2017-06-12 |
2022-02-08 |
Obsidian Therapeutics, Inc. |
PDE5 compositions and methods for immunotherapy
|
|
WO2019006427A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
WALL MODEL FOR ASSESSING TOXICITIES ASSOCIATED WITH IMMUNOTHERAPIES
|
|
CA3067914A1
(en)
|
2017-06-30 |
2019-01-03 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
WO2019025800A1
(en)
*
|
2017-08-02 |
2019-02-07 |
Autolus Limited |
CELLS EXPRESSING A CHIMERIC ANTIGENIC RECEPTOR OR A MANIPULATED TCR AND COMPRISING A SELECTIVELY EXPRESSED SELECTIVE NUCLEOTIDE SEQUENCE
|
|
EP3665308A1
(en)
|
2017-08-07 |
2020-06-17 |
The Johns Hopkins University |
Methods and materials for assessing and treating cancer
|
|
CN107383196B
(zh)
*
|
2017-08-30 |
2019-12-17 |
广州百暨基因科技有限公司 |
人源化抗cd19的抗原结合片段
|
|
EP3676403A1
(en)
|
2017-09-01 |
2020-07-08 |
Juno Therapeutics, Inc. |
Gene expression and assessment of risk of developing toxicity following cell therapy
|
|
US10501539B2
(en)
*
|
2017-09-15 |
2019-12-10 |
Lentigen Technology Inc. |
Compositions and methods for treating cancer with anti-CD19 immunotherapy
|
|
CN111194350A
(zh)
|
2017-09-18 |
2020-05-22 |
博雅辑因(北京)生物科技有限公司 |
一种基因编辑t细胞及其用途
|
|
CA3076337A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
WO2019067015A1
(en)
*
|
2017-09-29 |
2019-04-04 |
City Of Hope |
RECEPTORS OF CHIMERIC ANTIGENS AND BISPECIFIC ANTIBODIES FOR THE TREATMENT OF COAT CELL LYMPHOMA
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
JP7084990B2
(ja)
|
2017-10-13 |
2022-06-15 |
ハープーン セラピューティクス,インク. |
三重特異性タンパク質と使用方法
|
|
US11999802B2
(en)
|
2017-10-18 |
2024-06-04 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
RU2020116579A
(ru)
|
2017-10-25 |
2021-11-25 |
Новартис Аг |
Способы получения клеток, экспрессирующих химерный антигенный рецептор
|
|
AU2018359224B2
(en)
|
2017-10-30 |
2023-10-05 |
Neuropore Therapies, Inc. |
Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
FI3703710T3
(fi)
|
2017-10-31 |
2024-10-09 |
Allogene Therapeutics Inc |
Menetelmiä ja koostumuksia allogeenisten kimeeristä antigeenireseptoria kantavien t-solujen annostelemiseksi refraktorisen ja/tai uusiutuneen suurisoluisen b-solulymfooman tai refraktorisen ja/tai uusiutuneen follikulaarisen lymfooman hoitamista varten
|
|
US11564946B2
(en)
|
2017-11-01 |
2023-01-31 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
SG11202003657VA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Process for producing a t cell composition
|
|
WO2019089855A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
|
KR102845789B1
(ko)
|
2017-11-01 |
2025-08-14 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B 세포 성숙 항원에 특이적인 키메라 항원 수용체 및 암호화 폴리뉴클레오타이드
|
|
US12193994B2
(en)
|
2017-11-06 |
2025-01-14 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and a gamma secretase inhibitor
|
|
EP3707246B1
(en)
*
|
2017-11-07 |
2023-06-07 |
City of Hope |
Treatment of cns lymphoma and systemic lymphoma with intracerebroventricularly administered cd19 car
|
|
US12024715B2
(en)
|
2017-11-07 |
2024-07-02 |
Temple University-Of The Commonwealth System Of Higher Education |
Compositions and methods for improved T cells
|
|
EP3707160A1
(en)
|
2017-11-10 |
2020-09-16 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Chimeric antigen receptors targeting tumor antigens
|
|
SG11202004512XA
(en)
|
2017-11-15 |
2020-06-29 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, cd19-targeting chimeric antigen receptor, and combination therapies
|
|
CA3082334A1
(en)
*
|
2017-11-20 |
2019-05-23 |
Julius-Maximilians-Universitat Wurzburg |
Cd19cart cells eliminate myeloma cells that express very low levels of cd19
|
|
WO2019104245A1
(en)
|
2017-11-22 |
2019-05-31 |
La Jolla Institute For Allergy And Immunology |
Use and production of engineered immune cells
|
|
CN109836493A
(zh)
*
|
2017-11-25 |
2019-06-04 |
深圳宾德生物技术有限公司 |
一种靶向cd19的单链抗体、嵌合抗原受体t细胞及其制备方法和应用
|
|
CA3083949A1
(en)
|
2017-11-30 |
2020-06-06 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
|
CN111989106A
(zh)
|
2017-12-01 |
2020-11-24 |
朱诺治疗学股份有限公司 |
基因工程化细胞的给药和调节方法
|
|
CN111465616B
(zh)
*
|
2017-12-06 |
2023-08-01 |
艾克隆株式会社 |
特异性识别恶性b细胞的抗体或其抗原结合片段、包含其的嵌合抗原受体及其用途
|
|
WO2019113557A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Process for producing a composition of engineered t cells
|
|
AU2018379091A1
(en)
|
2017-12-08 |
2020-06-25 |
Juno Therapeutics, Inc. |
Serum-free media formulation for culturing cells and methods of use thereof
|
|
CN107880128B
(zh)
*
|
2017-12-21 |
2021-03-02 |
常州费洛斯药业科技有限公司 |
一种抗cd19的全人源抗体或抗体片段及其方法和应用
|
|
CN109053899B
(zh)
|
2017-12-22 |
2021-11-16 |
湖南远泰生物技术有限公司 |
一种含人转铁蛋白抗原表位序列的嵌合体抗原受体
|
|
MY202687A
(en)
*
|
2017-12-23 |
2024-05-15 |
Uwell Biopharma Inc |
Pharmaceutical chimeric receptor composition and method thereof
|
|
CA3086832A1
(en)
|
2018-01-03 |
2019-07-11 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
|
JP2021510540A
(ja)
*
|
2018-01-11 |
2021-04-30 |
イノベイティブ セルラー セラピューティクス インク.Innovative Cellular Therapeutics Inc. |
修飾細胞の増幅およびその応用
|
|
US10561686B2
(en)
|
2018-01-12 |
2020-02-18 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
US11679129B2
(en)
*
|
2018-01-12 |
2023-06-20 |
Curocell, Inc. |
Enhanced immune cells using dual shRNA and composition including the same
|
|
AU2019209428B2
(en)
|
2018-01-22 |
2025-06-26 |
Endocyte, Inc. |
Methods of use for CAR T cells
|
|
CN108017717B
(zh)
*
|
2018-01-24 |
2019-08-16 |
首都医科大学宣武医院 |
一种用于体外高效定向扩增的嵌合抗原受体及其应用
|
|
CN110093359B
(zh)
*
|
2018-01-29 |
2023-10-13 |
华南生物医药研究院 |
含cd3启动子序列和car序列的可分离的核酸及应用
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
CA3090089A1
(en)
|
2018-02-06 |
2019-08-15 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
US12180457B2
(en)
|
2018-02-06 |
2024-12-31 |
Seattle Children's Hospital |
Closed-system manufacturing process for CAR-T cells
|
|
SG11202007156QA
(en)
|
2018-02-09 |
2020-08-28 |
Nat Univ Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
EP3757133A4
(en)
*
|
2018-02-11 |
2021-12-01 |
Jiangsu Hengrui Medicine Co., Ltd. |
ISOLATED ANTIGENIC CHEMICAL RECEPTOR, MODIFIED T LYMPHOCYTE INCLUDING IT AND ASSOCIATED USE
|
|
US12331114B2
(en)
*
|
2018-02-13 |
2025-06-17 |
Indian Institute Of Technology Bombay |
Humanized anti-CD19 chimeric antigen receptor, its nucleic acid sequence and its preparation
|
|
EP3752203A1
(en)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
TW202000229A
(zh)
|
2018-02-23 |
2020-01-01 |
美商安德賽特公司 |
Car t細胞療法之順序方法
|
|
US20210046159A1
(en)
|
2018-03-09 |
2021-02-18 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
|
EA202091982A1
(ru)
|
2018-03-14 |
2021-06-10 |
Сиэтл Чилдрен'С Хоспитал (Дба Сиэтл Чилдрен'С Ресёрч Инститьют) |
Химерный антигенный рецептор к рецептору il-13 альфа 2 (il13r2) для опухолеспецифической т-клеточной иммунотерапии
|
|
JP7314161B2
(ja)
|
2018-03-14 |
2023-07-25 |
シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) |
ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法
|
|
US20210017277A1
(en)
*
|
2018-03-14 |
2021-01-21 |
The United States Of America,As Represented By The Secretary,Department Of Health And Human Services |
Anti-cd33 chimeric antigen receptors and their uses
|
|
US10751399B2
(en)
|
2018-03-20 |
2020-08-25 |
Cho Pharma Usa, Inc. |
Chimeric antigen receptors that bind to SSEA4 and uses thereof
|
|
SG11202008976YA
(en)
|
2018-04-02 |
2020-10-29 |
Nat Univ Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
WO2019200252A1
(en)
|
2018-04-13 |
2019-10-17 |
The Johns Hopkins University |
Non-invasive detection of response to immunotherapy
|
|
US20210079384A1
(en)
|
2018-04-13 |
2021-03-18 |
The Johns Hopkins University |
Non-invasive detection of response to a targeted therapy
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
CA3097679A1
(en)
|
2018-05-09 |
2019-11-14 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Antibodies specific to human nectin4
|
|
EP3794348A4
(en)
|
2018-05-18 |
2022-03-09 |
The Johns Hopkins University |
Cell-free dna for assessing and/or treating cancer
|
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
MX2020013017A
(es)
*
|
2018-06-01 |
2021-03-02 |
Mayo Found Medical Education & Res |
Materiales y metodos para tratar cancer.
|
|
KR20250151605A
(ko)
|
2018-06-01 |
2025-10-21 |
노파르티스 아게 |
Bcma에 대한 결합 분자 및 이의 용도
|
|
EP4403224A3
(en)
*
|
2018-06-01 |
2024-07-31 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
|
WO2019237035A1
(en)
|
2018-06-08 |
2019-12-12 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
JP7438988B2
(ja)
|
2018-06-13 |
2024-02-27 |
ノバルティス アーゲー |
Bcmaキメラ抗原受容体及びその使用
|
|
KR20190141511A
(ko)
*
|
2018-06-14 |
2019-12-24 |
주식회사 녹십자랩셀 |
신규 펩티드, 이를 포함하는 키메라 항원 수용체 및 이를 발현하는 면역 세포
|
|
EP3793578A4
(en)
*
|
2018-06-22 |
2022-03-23 |
The General Hospital Corporation |
Chimeric antigen receptors targeting cd37 and cd19
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
JP2021532116A
(ja)
|
2018-07-23 |
2021-11-25 |
マジェンタ セラピューティクス インコーポレイテッドMagenta Therapeutics, Inc. |
同種異系の細胞療法における抗−cd5抗体薬物コンジュゲート(adc)の使用
|
|
CN110819679A
(zh)
*
|
2018-08-07 |
2020-02-21 |
上海恒润达生生物科技有限公司 |
一种评估cart细胞体内代谢的方法
|
|
MX2021001519A
(es)
|
2018-08-09 |
2021-05-27 |
Juno Therapeutics Inc |
Metodos para valorar acidos nucleicos integrados.
|
|
US12486514B2
(en)
|
2018-08-29 |
2025-12-02 |
National University Of Singapore |
Method to specifically stimulate survival and expansion of genetically-modified immune cells
|
|
US12240915B2
(en)
|
2018-08-30 |
2025-03-04 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
|
TW202026006A
(zh)
*
|
2018-08-30 |
2020-07-16 |
美商Tcr2療法股份有限公司 |
使用融合蛋白進行tcr再程式化之組成物及方法
|
|
EP3844267B1
(en)
|
2018-08-31 |
2025-06-25 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
|
EP3843778A1
(en)
|
2018-08-31 |
2021-07-07 |
Invectys Sa |
Chimeric antigen receptors against multiple hla-g isoforms
|
|
EP3844265A2
(en)
|
2018-08-31 |
2021-07-07 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
CN113286817B
(zh)
|
2018-09-25 |
2025-01-28 |
哈普恩治疗公司 |
Dll3结合蛋白及使用方法
|
|
US20210347851A1
(en)
*
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
WO2020069405A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
|
MX2021003435A
(es)
|
2018-09-28 |
2021-06-15 |
Massachusetts Inst Technology |
Moleculas inmunomoduladoras localizadas en el colageno y metodos de las mismas.
|
|
US12522660B2
(en)
|
2018-10-31 |
2026-01-13 |
C3S2 Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
|
CA3117720A1
(en)
|
2018-11-06 |
2020-05-14 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
|
WO2020097403A1
(en)
|
2018-11-08 |
2020-05-14 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
|
SG11202105084VA
(en)
|
2018-11-16 |
2021-06-29 |
Juno Therapeutics Inc |
Methods of dosing engineered t cells for the treatment of b cell malignancies
|
|
US10918667B2
(en)
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
|
WO2020108090A1
(en)
*
|
2018-11-29 |
2020-06-04 |
Zhejiang Ruijiamei Biotech Co., Ltd. |
Car-t cells with humanized cd19 scfv with mutation in cdr 1 region
|
|
ES2986007T3
(es)
|
2018-11-30 |
2024-11-08 |
Juno Therapeutics Inc |
Métodos para la dosificación y el tratamiento de neoplasias malignas de linfocitos B en terapia celular adoptiva
|
|
FI3886875T3
(fi)
|
2018-11-30 |
2024-07-23 |
Juno Therapeutics Inc |
Adoptiivista soluterapiaa käyttäviä hoitomenetelmiä
|
|
CN120005921A
(zh)
|
2018-12-12 |
2025-05-16 |
凯德药业股份有限公司 |
嵌合抗原和t细胞受体及使用的方法
|
|
WO2020124021A1
(en)
*
|
2018-12-13 |
2020-06-18 |
The General Hospital Corporation |
Chimeric antigen receptors targeting cd79b and cd19
|
|
EP3898946B1
(en)
|
2018-12-19 |
2023-02-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mucosal-associated invariant t (mait) cells expressing chimeric antigen receptors
|
|
MX2021007392A
(es)
|
2018-12-20 |
2021-08-24 |
Novartis Ag |
Regimen de dosificacion y combinacion farmaceutica que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
|
AU2020206117A1
(en)
*
|
2019-01-07 |
2021-07-29 |
Regeneron Pharmaceuticals, Inc. |
Use of an anti-CD45 antibody drug conjugate (ADC) in cell therapy
|
|
CN109734813B
(zh)
*
|
2019-01-28 |
2022-06-17 |
广东昭泰体内生物医药科技有限公司 |
一种嵌合抗原受体及其应用
|
|
CN113710253A
(zh)
*
|
2019-02-04 |
2021-11-26 |
普洛迈博生物技术公司 |
编码嵌合抗原受体和il-6或检查点抑制剂的短发夹rna序列的核酸序列
|
|
WO2020163448A1
(en)
*
|
2019-02-06 |
2020-08-13 |
The Regents Of The University Of Michigan |
Chimeric antigen receptors targeting abnormal glycobiology
|
|
BR112021015783A2
(pt)
|
2019-02-15 |
2021-10-05 |
Novartis Ag |
Derivados de 3-(1-oxo-5-(piperidin-4-il)isoindolin-2-il)piperidina-2,6-diona e usos dos mesmos
|
|
WO2020165834A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3930763A1
(en)
|
2019-02-25 |
2022-01-05 |
Novartis AG |
Mesoporous silica particles compositions for viral delivery
|
|
KR20210137085A
(ko)
|
2019-03-05 |
2021-11-17 |
엔카르타, 인크. |
Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
|
|
CN113710705B
(zh)
|
2019-03-05 |
2023-07-21 |
湖南远泰生物技术有限公司 |
具有人源化cd19 scfv的car-t细胞
|
|
MX2021010840A
(es)
|
2019-03-08 |
2022-01-19 |
Obsidian Therapeutics Inc |
Composiciones de anhidrasa carbónica 2 (ca2) humana y métodos de regulación ajustable.
|
|
US20230074800A1
(en)
|
2019-03-21 |
2023-03-09 |
Novartis Ag |
Car-t cell therapies with enhanced efficacy
|
|
JP2022526194A
(ja)
|
2019-04-10 |
2022-05-23 |
エレベートバイオ テクノロジーズ,インコーポレイテッド |
Flt3特異的キメラ抗原受容体およびその使用方法
|
|
KR20210152515A
(ko)
|
2019-04-12 |
2021-12-15 |
씨4 테라퓨틱스, 인코포레이티드 |
이카로스 및 아이올로스의 트리시클릭 분해제
|
|
US20220168389A1
(en)
|
2019-04-12 |
2022-06-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
EP3959320A1
(en)
|
2019-04-24 |
2022-03-02 |
Novartis AG |
Compositions and methods for selective protein degradation
|
|
TWI905099B
(zh)
|
2019-05-21 |
2025-11-21 |
瑞士商諾華公司 |
Cd19 結合分子及其用途
|
|
EP4549555A3
(en)
*
|
2019-05-24 |
2025-07-30 |
City of Hope |
Ccr4 targeted chimeric antigen receptor modified t cells for treatment of ccr4 positive malignancies
|
|
EP3980450A4
(en)
*
|
2019-06-04 |
2024-06-19 |
Nkarta, Inc. |
Combinations of engineered natural killer cells and engineered t cells for immunotherapy
|
|
CA3139965A1
(en)
|
2019-06-07 |
2020-12-10 |
Ivie AIFUWA |
Automated t cell culture
|
|
MA56206A
(fr)
|
2019-06-12 |
2022-04-20 |
Juno Therapeutics Inc |
Combinaison thérapeutique d'une thérapie cytotoxique à médiation cellulaire et d'un inhibiteur d'une protéine de la famille bcl2 pro-survie
|
|
US11642409B2
(en)
|
2019-06-26 |
2023-05-09 |
Massachusetts Insttute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
CN112390891B
(zh)
*
|
2019-08-14 |
2022-06-03 |
苏州方德门达新药开发有限公司 |
嵌合抗原受体及其构建方法和应用
|
|
US20220298222A1
(en)
|
2019-08-22 |
2022-09-22 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
|
EP4021485A1
(en)
*
|
2019-08-28 |
2022-07-06 |
King's College London |
B cell targeted parallel car (pcar) therapeutic agents
|
|
EP4028413A1
(en)
|
2019-09-10 |
2022-07-20 |
Obsidian Therapeutics, Inc. |
Ca2-il15 fusion proteins for tunable regulation
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
IL292319B2
(en)
|
2019-10-30 |
2026-01-01 |
C3S2 Gmbh |
Cell selection and/or stimulation devices and methods of use
|
|
IL292924A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Chimeric antigen receptors cd19 and cd22 and their uses
|
|
CN114761037A
(zh)
|
2019-11-26 |
2022-07-15 |
诺华股份有限公司 |
结合bcma和cd19的嵌合抗原受体及其用途
|
|
IL293430A
(en)
|
2019-12-06 |
2022-07-01 |
Juno Therapeutics Inc |
Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
|
|
CN115335399A
(zh)
|
2019-12-06 |
2022-11-11 |
朱诺治疗学股份有限公司 |
针对gprc5d靶结合结构域的抗独特型抗体以及相关组合物和方法
|
|
CN115398231A
(zh)
|
2019-12-06 |
2022-11-25 |
朱诺治疗学股份有限公司 |
与治疗b细胞恶性肿瘤的细胞疗法相关的毒性和反应的相关方法
|
|
TW202135859A
(zh)
|
2019-12-20 |
2021-10-01 |
瑞士商諾華公司 |
組合療法
|
|
WO2021136415A1
(zh)
|
2019-12-30 |
2021-07-08 |
博雅辑因(北京)生物科技有限公司 |
一种纯化ucart细胞的方法与应用
|
|
CN114901813A
(zh)
|
2019-12-30 |
2022-08-12 |
博雅缉因(北京)生物科技有限公司 |
一种靶向t细胞淋巴瘤细胞的通用型car-t及其制备方法和应用
|
|
CN115397974A
(zh)
|
2020-01-23 |
2022-11-25 |
儿童医疗中心有限公司 |
由人类多能干细胞进行无基质t细胞分化
|
|
EP4100428A4
(en)
|
2020-02-04 |
2024-03-06 |
Seattle Children's Hospital (DBA Seattle Children's Research Institute) |
CHIMERIC ANTI-DINITROPHENOL ANTIGEN RECEPTORS
|
|
EP4104187A1
(en)
|
2020-02-14 |
2022-12-21 |
Novartis AG |
Method of predicting response to chimeric antigen receptor therapy
|
|
BR112022015909A2
(pt)
|
2020-02-14 |
2022-10-04 |
Univ Johns Hopkins |
Métodos e materiais para avaliação de ácidos nucleicos
|
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
|
WO2021173674A1
(en)
|
2020-02-26 |
2021-09-02 |
A2 Biotherapeutics, Inc. |
Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
|
|
BR112022016633A2
(pt)
|
2020-02-27 |
2022-12-13 |
Novartis Ag |
Métodos para produzir células que expressam receptor de antígeno quimérico
|
|
KR20220146530A
(ko)
|
2020-02-27 |
2022-11-01 |
노파르티스 아게 |
키메라 항원 수용체-발현 세포의 제조 방법
|
|
TWI886220B
(zh)
|
2020-02-28 |
2025-06-11 |
美商千禧製藥公司 |
用於自富潛能幹細胞生產自然殺手細胞之方法
|
|
US20230085724A1
(en)
|
2020-03-05 |
2023-03-23 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
|
WO2021183207A1
(en)
|
2020-03-10 |
2021-09-16 |
Massachusetts Institute Of Technology |
COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY OF NPM1c-POSITIVE CANCER
|
|
IL296242A
(en)
|
2020-03-10 |
2022-11-01 |
Massachusetts Inst Technology |
Methods for producing engineered memory-like nk cells and preparations containing them
|
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技(香港)有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
|
CN111484561A
(zh)
*
|
2020-04-07 |
2020-08-04 |
北京荣瑷医学生物科技有限责任公司 |
一种靶向于cd19分子的嵌合抗原受体
|
|
CN111411085A
(zh)
*
|
2020-04-10 |
2020-07-14 |
格源致善(上海)生物科技有限公司 |
一种嵌合抗原受体t细胞及其应用
|
|
US12378521B2
(en)
|
2020-04-15 |
2025-08-05 |
Amgen Inc. |
Method for enhancing production of genetically engineered autologous T cells
|
|
JP7626780B2
(ja)
*
|
2020-04-15 |
2025-02-04 |
アムジエン・インコーポレーテツド |
遺伝子改変自己t細胞を製造するためのプロセス
|
|
US12241086B2
(en)
|
2020-04-15 |
2025-03-04 |
Amgen Inc. |
Process for generating genetically engineered autologous T cells
|
|
IL297688A
(en)
|
2020-04-28 |
2022-12-01 |
Juno Therapeutics Inc |
Combination of bcma-directed t cell therapy and an immunomodulatory compound
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US12433954B2
(en)
|
2020-05-01 |
2025-10-07 |
Massachusetts Institute Of Technology |
Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs
|
|
JP2023526278A
(ja)
|
2020-05-13 |
2023-06-21 |
ジュノー セラピューティクス インコーポレイテッド |
組み換え受容体を発現しているドナーバッチ細胞を産生するための方法
|
|
EP4150640A1
(en)
|
2020-05-13 |
2023-03-22 |
Juno Therapeutics, Inc. |
Methods of identifying features associated with clinical response and uses thereof
|
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
|
KR20230024967A
(ko)
*
|
2020-06-11 |
2023-02-21 |
노파르티스 아게 |
Zbtb32 억제제 및 이의 용도
|
|
WO2021260528A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN111733186A
(zh)
*
|
2020-07-03 |
2020-10-02 |
天津英科赛奥科技有限公司 |
靶向cd19的人源化嵌合抗原受体制备及其应用
|
|
KR102594083B1
(ko)
|
2020-07-07 |
2023-10-25 |
칸큐어 엘엘씨 |
Mic 항체 및 결합제 및 이의 사용 방법
|
|
CA3188656A1
(en)
|
2020-07-17 |
2022-01-20 |
Simurx, Inc. |
Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
|
JP7819176B2
(ja)
|
2020-08-03 |
2026-02-24 |
ノバルティス アーゲー |
ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
WO2022031597A1
(en)
|
2020-08-03 |
2022-02-10 |
Kyverna Therapeutics, Inc. |
Methods of producing t regulatory cells, methods of transducing t cells, and uses of the same
|
|
US20230324408A1
(en)
|
2020-08-05 |
2023-10-12 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
|
WO2022035794A1
(en)
|
2020-08-13 |
2022-02-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Igg4 hinge-containing chimeric antigen receptors targeting glypican-1 (gpc1) for treating solid tumors
|
|
WO2022040586A2
(en)
|
2020-08-21 |
2022-02-24 |
Novartis Ag |
Compositions and methods for in vivo generation of car expressing cells
|
|
CN114438034A
(zh)
*
|
2020-11-06 |
2022-05-06 |
上海赛比曼生物科技有限公司 |
一种基因修饰的细胞制备方法
|
|
WO2022097061A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
|
MX2023005609A
(es)
|
2020-11-13 |
2023-05-29 |
Novartis Ag |
Terapias de combinacion con celulas que expresan receptores quimericos para el antigeno (car).
|
|
CN116848147A
(zh)
*
|
2020-11-20 |
2023-10-03 |
先声再明医药有限公司 |
Cd19人源化抗体及其应用
|
|
CN116635519A
(zh)
*
|
2020-11-26 |
2023-08-22 |
上海医药集团生物治疗技术有限公司 |
一种经修饰的免疫细胞及其应用
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
CN116635064A
(zh)
|
2020-12-18 |
2023-08-22 |
世纪治疗股份有限公司 |
具有适应性受体特异性的嵌合抗原受体系统
|
|
AU2021413365A1
(en)
|
2020-12-30 |
2023-07-20 |
Precigen, Inc. |
Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof
|
|
TW202242121A
(zh)
|
2021-01-11 |
2022-11-01 |
美商薩那生物科技公司 |
靶向cd8之病毒載體之用途
|
|
US20240425563A1
(en)
*
|
2021-01-13 |
2024-12-26 |
Washington University |
MHC-INDEPENDENT TCRs AND METHODS OF MAKING AND USING SAME
|
|
US20240115607A1
(en)
|
2021-01-26 |
2024-04-11 |
Cytocares (Shanghai) Inc. |
Chimeric antigen receptor (car) constructs and nk cells expressing car constructs
|
|
WO2022165419A1
(en)
|
2021-02-01 |
2022-08-04 |
Kyverna Therapeutics, Inc. |
Methods for increasing t-cell function
|
|
WO2022180586A1
(en)
*
|
2021-02-25 |
2022-09-01 |
Senthil Natesan |
Car t-cell product and method of preparation thereof
|
|
US20240108654A1
(en)
|
2021-03-03 |
2024-04-04 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and a dgk inhibitor
|
|
CA3210581A1
(en)
|
2021-03-22 |
2022-09-29 |
Neil HAIG |
Methods of determining potency of a therapeutic cell composition
|
|
JP2024513054A
(ja)
*
|
2021-03-29 |
2024-03-21 |
ジュノー セラピューティクス インコーポレイテッド |
リンパ腫の治療のためのcar t細胞療法および免疫調節化合物の組合せ
|
|
US20240181052A1
(en)
|
2021-03-29 |
2024-06-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
AU2022258832A1
(en)
|
2021-04-16 |
2023-10-19 |
Celgene Corporation |
Combination therapies with bcma-directed t cell therapy
|
|
CA3214280A1
(en)
|
2021-04-16 |
2022-10-20 |
Julie Ann RYTLEWSKI |
T cell therapy in patients who have had prior stem cell transplant
|
|
AU2022267891A1
(en)
|
2021-04-27 |
2023-11-09 |
Novartis Ag |
Viral vector production system
|
|
WO2022234158A1
(es)
*
|
2021-05-06 |
2022-11-10 |
Institut D'investigacions Biomèdiques August Pi I Sunyer (Idibaps) |
Terapia de células t con receptor de antígeno quimérico específico de cd19
|
|
KR20240018454A
(ko)
|
2021-05-06 |
2024-02-13 |
주노 테라퓨틱스 게엠베하 |
T 세포의 자극 및 형질도입 방법
|
|
WO2022248602A1
(en)
|
2021-05-25 |
2022-12-01 |
Institut Curie |
Myeloid cells overexpressing bcl2
|
|
BR112023022097A2
(pt)
|
2021-06-07 |
2023-12-19 |
Agonox Inc |
Cxcr5, pd-1 e icos expressando células t cd4 reativas de tumor e seu uso
|
|
MX2023014979A
(es)
|
2021-06-15 |
2024-02-09 |
Takeda Pharmaceuticals Co |
Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes.
|
|
CN113549600B
(zh)
*
|
2021-06-30 |
2022-08-30 |
徐州医科大学 |
一种具有CD19的特异性抗性的CAR-iNKT细胞
|
|
TW202321457A
(zh)
|
2021-08-04 |
2023-06-01 |
美商薩那生物科技公司 |
靶向cd4之病毒載體之用途
|
|
EP4384621A4
(en)
*
|
2021-08-09 |
2025-04-09 |
The Trustees of The University of Pennsylvania |
OPTIMIZATION OF T LYMPHOCYTE DIFFERENTIATION STATE WITH MICRORNAS
|
|
WO2023021477A1
(en)
|
2021-08-20 |
2023-02-23 |
Novartis Ag |
Methods of making chimeric antigen receptor–expressing cells
|
|
KR20240112994A
(ko)
|
2021-11-03 |
2024-07-19 |
셀진 코포레이션 |
골수종을 치료하는 데 사용하기 위한 b-세포 성숙 항원에 특이적인 키메라 항원 수용체
|
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
JP2024540360A
(ja)
|
2021-11-09 |
2024-10-31 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
グリピカン-3(GPC3)を標的にするIgG4ヒンジ含有キメラ抗原受容体およびその使用
|
|
WO2023115041A1
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
|
EP4448549A2
(en)
|
2021-12-17 |
2024-10-23 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
|
WO2023150518A1
(en)
|
2022-02-01 |
2023-08-10 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
|
JP2025506171A
(ja)
|
2022-02-15 |
2025-03-07 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
Gpc2を標的とする、cd28ヒンジおよび膜貫通含有キメラ抗原受容体、ならびにその使用
|
|
EP4479143A1
(en)
|
2022-02-18 |
2024-12-25 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance
|
|
WO2023193015A1
(en)
|
2022-04-01 |
2023-10-05 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
|
EP4516909A1
(en)
*
|
2022-04-29 |
2025-03-05 |
Shanghai Simnova Biotechnology Co., Ltd. |
Cd19-targeting chimeric antigen receptor and use thereof
|
|
WO2023215738A1
(en)
|
2022-05-02 |
2023-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compositions targeting gpc2 and gpc3 and their use for treating solid tumors
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
US20250297282A1
(en)
|
2022-05-05 |
2025-09-25 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
US20250302954A1
(en)
|
2022-05-11 |
2025-10-02 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
|
KR20250008774A
(ko)
|
2022-05-11 |
2025-01-15 |
셀진 코포레이션 |
T 세포 요법 및 그의 생산과 관련된 방법 및 용도
|
|
US20250345432A1
(en)
|
2022-05-25 |
2025-11-13 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
|
WO2023237663A1
(en)
|
2022-06-09 |
2023-12-14 |
Institut National de la Santé et de la Recherche Médicale |
Use of the f359l missense irf4 variant for increasing the stability of regulatory t cells
|
|
US20250381272A1
(en)
|
2022-06-22 |
2025-12-18 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
JP2025523107A
(ja)
*
|
2022-07-15 |
2025-07-17 |
アルバート アインシュタイン カレッジ オブ メディスン |
Tmigd2共刺激ドメインを含むキメラ抗原受容体及びその使用方法
|
|
JP2025528459A
(ja)
|
2022-08-31 |
2025-08-28 |
アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル(インセルム) |
より効率的なcar-t細胞を生成する方法
|
|
EP4583876A1
(en)
|
2022-09-08 |
2025-07-16 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
|
JP2025531220A
(ja)
|
2022-09-15 |
2025-09-19 |
ノバルティス アーゲー |
キメラ抗原受容体療法を使用した自己免疫障害の治療
|
|
EP4598565A1
(en)
|
2022-10-07 |
2025-08-13 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate improving car-t cells
|
|
EP4602174A1
(en)
|
2022-10-13 |
2025-08-20 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
|
JP2025535365A
(ja)
*
|
2022-10-18 |
2025-10-24 |
カイト ファーマ インコーポレイテッド |
Il18と結合した新規cd19結合体を含むcar-t構築物およびその使用方法
|
|
WO2024089639A1
(en)
|
2022-10-26 |
2024-05-02 |
Novartis Ag |
Lentiviral formulations
|
|
EP4611798A1
(en)
|
2022-11-02 |
2025-09-10 |
Celgene Corporation |
Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
|
|
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(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
CN116063575A
(zh)
*
|
2022-11-15 |
2023-05-05 |
北京瑜阳科技有限公司 |
一种嵌合抗原受体(car)以及在治疗肿瘤中的应用
|
|
JP2026501122A
(ja)
|
2022-12-09 |
2026-01-14 |
ジュノー セラピューティクス インコーポレイテッド |
ホログラフィックイメージングを使用して細胞表現型を予測するための機械学習方法
|
|
WO2024133052A1
(en)
*
|
2022-12-19 |
2024-06-27 |
Universität Basel Vizerektorat Forschung |
T-cell receptor fusion protein
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
AU2024244733B2
(en)
|
2023-03-31 |
2025-12-11 |
AbelZeta Inc. |
Bispecific chimeric antigen receptors targeting cd20 and bcma
|
|
EP4698665A1
(en)
|
2023-04-18 |
2026-02-25 |
Sana Biotechnology, Inc. |
Engineered protein g fusogens and related lipid particles and methods thereof
|
|
EP4698666A1
(en)
|
2023-04-18 |
2026-02-25 |
Sana Biotechnology, Inc. |
Universal protein g fusogens and adapter systems thereof and related lipid particles and uses
|
|
WO2024220598A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Lentiviral vectors with two or more genomes
|
|
CN121311765A
(zh)
|
2023-04-18 |
2026-01-09 |
朱诺治疗学股份有限公司 |
评估治疗性细胞组合物的效力的细胞毒性测定
|
|
KR20260006623A
(ko)
|
2023-04-28 |
2026-01-13 |
센젠 센신 바이오테크놀로지 컴퍼니 리미티드 |
변형된 전달 담체 및 이의 용도
|
|
KR20260026101A
(ko)
|
2023-05-23 |
2026-02-25 |
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T 세포의 활성화 마커 및 t 세포 활성화를 평가하는 방법
|
|
WO2024251263A1
(en)
|
2023-06-09 |
2024-12-12 |
Jw Therapeutics R & D (Shanghai) Co., Ltd. |
Fusion protein and medical use thereof
|
|
WO2025054202A1
(en)
|
2023-09-05 |
2025-03-13 |
Sana Biotechnology, Inc. |
Method of screening a sample comprising a transgene with a unique barcode
|
|
WO2025051339A1
(en)
|
2023-09-05 |
2025-03-13 |
Tiber Biotech Srl |
SINGLE-CHAIN VARIABLE FRAGMENT AND MOLECULES DERIVING THEREFROM THAT BIND FRAGMENT TRVB5-1 OF THE β CHAIN OF HUMAN T-CELL RECEPTOR
|
|
WO2025072450A1
(en)
|
2023-09-26 |
2025-04-03 |
Werewolf Therapeutics, Inc. |
Enhanced adoptive cell therapy
|
|
WO2025125363A1
(en)
|
2023-12-11 |
2025-06-19 |
Institut National de la Santé et de la Recherche Médicale |
Host cells engineered to bypass the cd28 co-stimulation pathway and uses thereof for inducing durable immune responses under non-inflammatory conditions
|
|
EP4574838A1
(en)
|
2023-12-21 |
2025-06-25 |
Vilnius University |
Chimeric antigen receptor (car) with enhanced recruitment of signaling partners
|
|
WO2025151838A1
(en)
|
2024-01-12 |
2025-07-17 |
Sana Biotechnology, Inc. |
Safety switches to control in vitro and in vivo proliferation of cell therapy products
|
|
WO2025171383A2
(en)
|
2024-02-09 |
2025-08-14 |
Dispatch Biotherapeutics, Inc. |
Engineered cancer antigens and related methods and uses
|
|
WO2025171388A1
(en)
|
2024-02-09 |
2025-08-14 |
Dispatch Biotherapeutics, Inc. |
Engineered cancer antigens with modified domains and related methods and uses
|
|
WO2025191300A1
(en)
|
2024-03-12 |
2025-09-18 |
Novartis Ag |
Rapcabtagene autoleucel for use in treating systemic lupus erythematosus
|
|
WO2025219870A1
(en)
*
|
2024-04-15 |
2025-10-23 |
Biocell Innovations Pte Ltd |
Modified cd19-targeted chimeric antigen receptor (car)-t cell and uses thereof
|
|
WO2025240781A2
(en)
|
2024-05-15 |
2025-11-20 |
Werewolf Therapeutics, Inc. |
Modified antibodies and immunoglobulin formats
|
|
WO2025242732A1
(en)
|
2024-05-21 |
2025-11-27 |
Institut National de la Santé et de la Recherche Médicale |
Pan antibodies against sars-cov-2 spike protein and uses thereof for therapeutical purposes
|
|
WO2025245381A1
(en)
|
2024-05-23 |
2025-11-27 |
The Trustrees Of Dartmouth College |
Methods and compositions for enhancing the persistence of car expressing tregs in the cns and other tissues
|
|
WO2026002973A1
(en)
|
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2026-01-02 |
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Host immune cells engineered to overexpress a foxk1 polypeptide
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|