HK1116088A1 - 基於增加活性劑對晶體微粒表面的親和力的藥物配方法 - Google Patents

基於增加活性劑對晶體微粒表面的親和力的藥物配方法

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Publication number
HK1116088A1
HK1116088A1 HK08110376.5A HK08110376A HK1116088A1 HK 1116088 A1 HK1116088 A1 HK 1116088A1 HK 08110376 A HK08110376 A HK 08110376A HK 1116088 A1 HK1116088 A1 HK 1116088A1
Authority
HK
Hong Kong
Prior art keywords
affinity
increasing
active agents
drug formulation
formulation based
Prior art date
Application number
HK08110376.5A
Other languages
English (en)
Inventor
Mark Hokenson
Keith A Oberg
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of HK1116088A1 publication Critical patent/HK1116088A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
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    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
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    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
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    • A61K9/5089—Processes
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK08110376.5A 2005-09-14 2008-09-19 基於增加活性劑對晶體微粒表面的親和力的藥物配方法 HK1116088A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71752405P 2005-09-14 2005-09-14
US74488206P 2006-04-14 2006-04-14
PCT/US2006/035822 WO2007033316A2 (en) 2005-09-14 2006-09-14 Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces

Publications (1)

Publication Number Publication Date
HK1116088A1 true HK1116088A1 (zh) 2008-12-19

Family

ID=37726824

Family Applications (2)

Application Number Title Priority Date Filing Date
HK08110376.5A HK1116088A1 (zh) 2005-09-14 2008-09-19 基於增加活性劑對晶體微粒表面的親和力的藥物配方法
HK08112118.4A HK1117768A1 (zh) 2005-09-14 2008-11-05 基於增加晶質微粒表面對活性劑的親和力的藥物配製方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK08112118.4A HK1117768A1 (zh) 2005-09-14 2008-11-05 基於增加晶質微粒表面對活性劑的親和力的藥物配製方法

Country Status (16)

Country Link
US (15) US7799344B2 (zh)
EP (3) EP1928423B1 (zh)
JP (4) JP5465878B2 (zh)
KR (7) KR101643478B1 (zh)
CN (3) CN104324362B (zh)
AU (2) AU2006290227B2 (zh)
BR (2) BRPI0615819B8 (zh)
CA (2) CA2620758C (zh)
DK (3) DK1937219T3 (zh)
ES (3) ES2555310T3 (zh)
HK (2) HK1116088A1 (zh)
HU (2) HUE028623T2 (zh)
IN (1) IN2014DN09128A (zh)
MX (2) MX358592B (zh)
RU (3) RU2394550C2 (zh)
WO (2) WO2007033316A2 (zh)

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