ES2857734T3 - Moléculas de unión a antígeno activadoras de linfocitos T biespecíficas - Google Patents
Moléculas de unión a antígeno activadoras de linfocitos T biespecíficas Download PDFInfo
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- ES2857734T3 ES2857734T3 ES17206703T ES17206703T ES2857734T3 ES 2857734 T3 ES2857734 T3 ES 2857734T3 ES 17206703 T ES17206703 T ES 17206703T ES 17206703 T ES17206703 T ES 17206703T ES 2857734 T3 ES2857734 T3 ES 2857734T3
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
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- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
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- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
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- C07K2317/00—Immunoglobulins specific features
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- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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| EP2417160A1 (en) * | 2009-04-07 | 2012-02-15 | Roche Glycart AG | Bispecific anti-erbb-1/anti-c-met antibodies |
| ES2537100T3 (es) * | 2009-04-07 | 2015-06-02 | Roche Glycart Ag | Anticuerpos biespecíficos trivalentes |
| BRPI1012589A2 (pt) * | 2009-04-07 | 2016-03-22 | Roche Glycart Ag | anticorpos bi-específicos anti-erbb-3/anti-c-met |
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