EP1928506A4 - Doppel-variabel-domänen-immunglobulin und seine verwendungen - Google Patents

Doppel-variabel-domänen-immunglobulin und seine verwendungen

Info

Publication number
EP1928506A4
EP1928506A4 EP06813554A EP06813554A EP1928506A4 EP 1928506 A4 EP1928506 A4 EP 1928506A4 EP 06813554 A EP06813554 A EP 06813554A EP 06813554 A EP06813554 A EP 06813554A EP 1928506 A4 EP1928506 A4 EP 1928506A4
Authority
EP
European Patent Office
Prior art keywords
variable domain
dual variable
domain immunoglobin
immunoglobin
dual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06813554A
Other languages
English (en)
French (fr)
Other versions
EP1928506A2 (de
Inventor
Chengbin Wu
Tariq Ghayur
Richard W Dixon
Jochen G Salfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Inc
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Priority to EP12162029A priority Critical patent/EP2500358A3/de
Priority to EP20120161985 priority patent/EP2500356A3/de
Priority to EP12161976A priority patent/EP2500355A3/de
Priority to EP12162057A priority patent/EP2500359A3/de
Priority to EP20120161999 priority patent/EP2500357A3/de
Priority to EP12162014A priority patent/EP2495257A3/de
Priority to EP12161964A priority patent/EP2500353A3/de
Priority to EP12161970A priority patent/EP2500354A3/de
Priority to EP12161953A priority patent/EP2500352A1/de
Priority to EP12162041A priority patent/EP2520588A1/de
Publication of EP1928506A2 publication Critical patent/EP1928506A2/de
Publication of EP1928506A4 publication Critical patent/EP1928506A4/de
Withdrawn legal-status Critical Current

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
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EP06813554A 2005-08-19 2006-08-18 Doppel-variabel-domänen-immunglobulin und seine verwendungen Withdrawn EP1928506A4 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP12162029A EP2500358A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP20120161985 EP2500356A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12161976A EP2500355A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12162057A EP2500359A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP20120161999 EP2500357A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12162014A EP2495257A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12161964A EP2500353A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12161970A EP2500354A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12161953A EP2500352A1 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12162041A EP2520588A1 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70991105P 2005-08-19 2005-08-19
US73289205P 2005-11-02 2005-11-02
PCT/US2006/032398 WO2007024715A2 (en) 2005-08-19 2006-08-18 Dual variable domain immunoglobin and uses thereof

Related Child Applications (9)

Application Number Title Priority Date Filing Date
EP12161964A Division EP2500353A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
EP12162057A Division EP2500359A3 (de) 2005-08-19 2006-08-18 Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
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SG2014010029A (en) 2014-08-28
BRPI0615026A8 (pt) 2018-03-06
TWI323734B (en) 2010-04-21
CN101370525A (zh) 2009-02-18
WO2007024715A9 (en) 2009-04-23
IL189543A (en) 2014-06-30
RU2008110494A (ru) 2009-09-27
KR20140053410A (ko) 2014-05-07
JP2009504191A (ja) 2009-02-05
TW200740849A (en) 2007-11-01
MY169746A (en) 2019-05-14
IL189543A0 (en) 2008-08-07
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RU2014110927A (ru) 2015-09-27
CA2618482A1 (en) 2007-03-01
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NZ597168A (en) 2013-07-26
WO2007024715A3 (en) 2008-10-30
BRPI0615026A2 (pt) 2009-06-16
AU2006283532A1 (en) 2007-03-01
RU2515108C2 (ru) 2014-05-10
ZA201306105B (en) 2014-05-28
ZA201100659B (en) 2012-12-27
IL232646A0 (en) 2014-06-30
KR20130108481A (ko) 2013-10-02
EP2495257A3 (de) 2012-10-17
EP2520588A1 (de) 2012-11-07
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