CH622099A5 - - Google Patents

Download PDF

Info

Publication number
CH622099A5
CH622099A5 CH665673A CH665673A CH622099A5 CH 622099 A5 CH622099 A5 CH 622099A5 CH 665673 A CH665673 A CH 665673A CH 665673 A CH665673 A CH 665673A CH 622099 A5 CH622099 A5 CH 622099A5
Authority
CH
Switzerland
Prior art keywords
hapten
enzyme
antibody
hrp
enzyme conjugate
Prior art date
Application number
CH665673A
Other languages
German (de)
English (en)
Inventor
Antonius Hermanus W M Schuurs
Bauke Klaas Van Weemen
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of CH622099A5 publication Critical patent/CH622099A5/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CH665673A 1972-05-11 1973-05-10 CH622099A5 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE7206373,A NL171930C (nl) 1972-05-11 1972-05-11 Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.

Publications (1)

Publication Number Publication Date
CH622099A5 true CH622099A5 (cs) 1981-03-13

Family

ID=19816017

Family Applications (1)

Application Number Title Priority Date Filing Date
CH665673A CH622099A5 (cs) 1972-05-11 1973-05-10

Country Status (18)

Country Link
US (1) US3879262A (cs)
JP (1) JPS5317648B2 (cs)
AR (1) AR200129A1 (cs)
AT (1) AT328612B (cs)
BE (1) BE799417A (cs)
BR (1) BR7303420D0 (cs)
CA (1) CA1011232A (cs)
CH (1) CH622099A5 (cs)
DE (1) DE2323467C2 (cs)
DK (1) DK135965B (cs)
ES (1) ES414618A1 (cs)
FI (1) FI52154C (cs)
FR (1) FR2184371A5 (cs)
GB (1) GB1433783A (cs)
HU (1) HU169436B (cs)
NL (1) NL171930C (cs)
SE (1) SE417015B (cs)
ZA (1) ZA732924B (cs)

Families Citing this family (844)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1451669A (en) * 1974-01-02 1976-10-06 Radiochemical Centre Ltd Protein staining
JPS5112922A (en) * 1974-07-19 1976-01-31 Eiken Chemical Kasuitaihorumonno sokuteihoho
FR2288312A1 (fr) * 1974-10-14 1976-05-14 Pasteur Institut Procede de dosage immunoenzymatique de la progesterone
NL7501215A (nl) * 1975-02-01 1976-08-03 Akzo Nv Methode voor het aantonen en bepalen van een antigeen of antilichaam.
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
JPS52108017A (en) * 1976-03-04 1977-09-10 Eiken Chemical Measurement for thyroid gland hormon
JPS5341420A (en) * 1976-09-29 1978-04-14 Mochida Pharm Co Ltd Immunochemically measuring methoa of hapten
JPS5386013A (en) * 1976-11-24 1978-07-29 Ajinomoto Co Inc Quantitative analysis of pituitary hormone
IT1153999B (it) * 1977-03-15 1987-01-21 Snam Progetti Composizione atta alla determinazione della triiodotironina e metodo diagnostico impiegante la stessa
US4197287A (en) * 1977-06-10 1980-04-08 Ventrex Laboratories Inc. Method and apparatus for performing in nitro clinical diagnostic tests using a solid phase assay system having special utility for use with automatic pipetting equipment
US4235960A (en) * 1977-07-29 1980-11-25 The Medical College Of Wisconsin, Inc. Competitive enzyme-linked immunoassay
CA1108516A (en) * 1977-11-21 1981-09-08 Stanley E. Charm Antibiotic detection method
US4231750A (en) * 1977-12-13 1980-11-04 Diagnostic Reagents, Inc. Methods for performing chemical assays using fluorescence and photon counting
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
US4376165A (en) * 1978-06-22 1983-03-08 Miles Laboratories, Inc. Method of preparing an enzyme-labeled ligand for use in specific binding assays and the labeled conjugate produced thereby
US4238565A (en) * 1978-06-22 1980-12-09 Miles Laboratories, Inc. Specific binding assay with a prosthetic group as a label component
FR2432713A1 (fr) * 1978-08-02 1980-02-29 Inst Nat Sante Rech Med Application de la d5,3-ceto steroide isomerase dans les dosages immunoenzymatiques
JPS5575822A (en) * 1978-12-05 1980-06-07 Niigataken Hydraulic bulging method for metallic container
NZ192377A (en) * 1978-12-29 1981-11-19 Nat Res Dev Monitoring pregnancy in milk-producing domestic animals
US4278653A (en) * 1979-02-01 1981-07-14 New England Nuclear Corporation Methods and kits for double antibody immunoassay providing a colored pellet for easy visualization
US4289748A (en) * 1979-05-31 1981-09-15 United States Of America Ultrasensitive enzymatic radioimmunoassay method
US4318982A (en) * 1979-06-04 1982-03-09 Miles Laboratories, Inc. FMN-Labeled specific binding assay
US4318983A (en) * 1979-06-04 1982-03-09 Miles Laboratories, Inc. Fad-labeled specific binding assay monitored with apoglutathione reductase or apolipoamide dehydrogenase
US4340668A (en) * 1979-06-04 1982-07-20 Miles Laboratories, Inc. Heme-labeled specific binding assay
JPS55162059A (en) * 1979-06-05 1980-12-17 Mochida Pharmaceut Co Ltd Measuring method for antigen, antibody or their complex and measurement reagent kit
FR2459479B1 (fr) * 1979-06-21 1983-07-08 Inst Nat Sante Rech Med Procede de separation d'une substance proteinique a partir d'une solution la contenant par filtration d'affinite et application dudit procede aux dosages enzymatiques
JPS564324A (en) * 1979-06-22 1981-01-17 Toupure Kk Bulging method
US4378344A (en) * 1979-09-28 1983-03-29 Ventrex Laboratories, Inc. Method and apparatus for performing multiple, simultaneous in vitro diagnostic tests using a solid phase system
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4410634A (en) * 1979-10-26 1983-10-18 Dynasciences Corporation Method of passively adsorbing immuno-reactive haptens to solid phases
AU6452480A (en) 1979-11-13 1982-05-27 Ventrex Laboratories Inc. Apparatus for carrying out solid phase in vitro diagnostic assays
WO1981001414A1 (en) * 1979-11-19 1981-05-28 Charles Hospital Dev An improved method of non homogenous enzyme immunoassay
US4347312A (en) * 1980-03-20 1982-08-31 Research Triangle Institute Detection of antibiotics in milk
JPS5714748A (en) * 1980-07-01 1982-01-26 Dainippon Pharmaceut Co Ltd Kit for quantitative determination of valproic acid and its method for quantitative determination
US4323647A (en) * 1980-10-15 1982-04-06 University Of Miami Steric hindrance enzyme immunoassay
JPS58500874A (ja) * 1981-06-02 1983-05-26 エレクトロ−ヌ−　クレオニツクス、インコ−ポレ−テツド 免疫沈殿分析
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
US4350659A (en) * 1981-07-30 1982-09-21 Corning Glass Works Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
US4506009A (en) * 1982-03-30 1985-03-19 University Of California Heterogeneous immunoassay method
US4535057A (en) * 1982-07-26 1985-08-13 Amf Incorporated Immunoassay employing monoclonal herpes simplex antibody and biotin-avidin detection system
US4861705A (en) * 1983-01-31 1989-08-29 Yeda Research And Development Company, Ltd. Method for removing components of biological fluids
US4778752A (en) * 1983-10-11 1988-10-18 Scripps Clinic And Research Foundation Receptors specific for hapten-modified self proteins
US4727022A (en) * 1984-03-14 1988-02-23 Syntex (U.S.A.) Inc. Methods for modulating ligand-receptor interactions and their application
DE3430905A1 (de) * 1984-08-22 1986-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung einer immunologisch bindefaehigen substanz
GB8428201D0 (en) * 1984-11-08 1984-12-19 Glaxo Group Ltd Biological preparations
US4760142A (en) * 1984-11-27 1988-07-26 Hoechst Celanese Corporation Divalent hapten derivatives
CH670709A5 (cs) * 1986-04-24 1989-06-30 Univ Moskovsk
US4868132A (en) * 1987-02-03 1989-09-19 Abbott Laboratories Fluorescence polarization immunoassay for amphetamine/methamphetamine
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
JPH0833394B2 (ja) * 1990-10-03 1996-03-29 三洋化成工業株式会社 酵素標識ハプテンの製法
EP0585310B1 (en) * 1991-04-10 1999-03-17 Biosite Diagnostics Inc. Crosstalk inhibitors and their uses
US6777190B1 (en) 1991-04-10 2004-08-17 Biosite, Inc. Crosstalk inhibitors and their uses
US5464749A (en) 1991-07-22 1995-11-07 Bayer Corporation Immunoassay of free substances in biological fluids
US5874423A (en) * 1992-09-10 1999-02-23 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Digitalis-like compounds
US5484709A (en) * 1993-09-10 1996-01-16 Ensys, Inc. Immunoassay method for detecting an immunologically non-remarkable compound, its components and a kit for use in performing the same
WO1995034640A1 (en) * 1994-06-13 1995-12-21 Henry Ford Health System A novel neuronal-neonatal gene: neuronatin
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5777093A (en) * 1995-05-16 1998-07-07 Ramot-University Authority For Applied Research & Industrial Development Ltd. cDNAs associated with ataxia-telangiectasia
US5858661A (en) 1995-05-16 1999-01-12 Ramot-University Authority For Applied Research And Industrial Development Ataxia-telangiectasia gene and its genomic organization
US5728807A (en) * 1995-05-16 1998-03-17 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Mutated proteins associated with ataxia-telangiectasia
US5840322A (en) * 1996-12-19 1998-11-24 Ramot-University Authority For Applied Research & Industrial Devel. Ltd. Anti-oral-microbial adhesion fraction derived from vaccinium
US20030104973A1 (en) * 1997-08-21 2003-06-05 Quark Biotech, Inc. Hypoxia-regulated genes
EP1009753B1 (en) 1997-08-21 2005-04-20 Quark Biotech, Inc. Hypoxia-regulated genes
US7973156B2 (en) * 1997-08-21 2011-07-05 Quark Pharmaceuticals Inc. Hypoxia-regulated genes
US6284496B1 (en) 1997-10-03 2001-09-04 University Of South Florida DNA vector for determining the presence of out-of-reading-frame mutations
AU748467B2 (en) 1997-10-17 2002-06-06 University Of South Florida Method to diagnose and monitor cellular immune deficiencies
US20080206206A1 (en) 1998-05-07 2008-08-28 University Of South Florida Bone marrow-derived neuronal cells
US6344443B1 (en) 1998-07-08 2002-02-05 University Of South Florida Peptide antagonists of tumor necrosis factor alpha
WO2000002561A1 (en) 1998-07-13 2000-01-20 University Of South Florida Modulation of the phospholipase a2 pathway as a therapeutic
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
CA2344653A1 (en) * 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
AU759719B2 (en) 1999-02-04 2003-04-17 Pluristem Ltd. Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells
US6440682B1 (en) * 1999-05-28 2002-08-27 Detroit R&D Inc. Detection of hypertension using immunoreactive metabolic products
US6787318B1 (en) * 1999-06-01 2004-09-07 Roskamp Research Institute, Llc Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
US6875582B1 (en) 1999-08-19 2005-04-05 Omniscience Pharmaceuticals, Inc. Methods and targets of antibiotic resistance
US7811981B2 (en) 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US7101839B1 (en) 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US6998232B1 (en) 1999-09-27 2006-02-14 Quark Biotech, Inc. Methods of diagnosing bladder cancer
IL149698A0 (en) 1999-11-19 2002-11-10 Yissum Res Dev Co Aspergillus niger beta-glucosidase gene, protein and uses thereof
US6544506B2 (en) * 2000-01-05 2003-04-08 Yeda Research & Development Co. Ltd. Veto cells effective in preventing graft rejection and devoid of graft versus host potential
US7385106B2 (en) * 2000-01-24 2008-06-10 Ramot At Tel Aviv University Ltd. Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
AU785493B2 (en) 2000-03-27 2008-01-03 Technion Research & Development Foundation Ltd. Single chain class I major histo-compatibility complexes, constructs encoding same and methods of generating same
US20040191260A1 (en) * 2003-03-26 2004-09-30 Technion Research & Development Foundation Ltd. Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
HUP0300810A2 (hu) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
PT1315519E (pt) 2000-08-08 2011-03-17 Technion Res & Dev Foundation Composições farmacêuticas e métodos úteis para tratamento de cancro e fibrose hepática
EP1683874A3 (en) 2000-08-29 2006-10-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
US7632522B2 (en) * 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
US20070281037A9 (en) * 2000-09-28 2007-12-06 Nanocyte Inc. Sterile preparations and compositions including stinging capsules and methods of producing and using same
AU2001295850A1 (en) 2000-09-28 2002-04-08 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
JP4243653B2 (ja) 2000-11-17 2009-03-25 ヴァスキュラー バイオジェニックス リミテッド 内皮細胞特異性を示すプロモーター及びその使用法
EP1341543A4 (en) 2000-11-24 2009-09-02 Vascular Biogenics Ltd METHODS INVOLVING DEFINED OXIDE PHOSPHOLIPIDS, AND COMPOSITIONS CONTAINING THE SAME, FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROSIS
EP1356298B1 (en) 2000-11-30 2011-05-18 Crawford Healthcare Holdings Limited Diagnosis of disease
US20040052769A1 (en) * 2000-11-30 2004-03-18 Yair Reisner Methods of utilizing cultured non-gvhd inducing t lymphocytes to treat disease
US7087395B1 (en) 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
CA2440317A1 (en) * 2001-01-17 2002-07-25 Ramot At Tel Aviv University Ltd. Chitinases, derived from carnivorous plants polynucleotide sequences encoding thereof, and methods of isolating and using same
CA2475021A1 (en) * 2001-01-31 2002-08-08 Dror Mevorach Induction of tolerance by apoptotic and/or necrotic cells
US20050202098A1 (en) * 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
US20030003454A1 (en) 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
US6770622B2 (en) 2001-06-08 2004-08-03 Gary A. Jarvis N-terminally truncated galectin-3 for use in treating cancer
MXPA04000397A (es) * 2001-07-19 2004-03-18 Yissum Res Dev Co Polipeptidos que tienen actividad catalitica de isomerasa de carotenoides, acidos nucleicos que los codifican y usos de los mismos.
US7442781B2 (en) 2001-08-16 2008-10-28 Urifer Ltd. Diagnosis, prevention and treatment of cancer
US7138144B2 (en) * 2001-09-07 2006-11-21 Nadir Askenasy Method of inducing immune tolerance via blood/lymph flow-restricted bone marrow transplantation
US20040136972A1 (en) 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
US20060068405A1 (en) * 2004-01-27 2006-03-30 Alex Diber Methods and systems for annotating biomolecular sequences
EP2277887A3 (en) 2001-10-19 2011-02-16 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AU2002358947A1 (en) * 2001-12-05 2003-06-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nanoparticles containing polymeric nucleic acid homologs, pharmaceutical compositions and articles of manufacture containing same and methods of use thereof
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
IL152904A0 (en) * 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (en) * 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US6992176B2 (en) * 2002-02-13 2006-01-31 Technion Research & Development Foundation Ltd. Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
JP2005533486A (ja) * 2002-02-20 2005-11-10 ダイアックス、コープ Ｍｈｃ−ペプチド複合体結合リガンド
WO2003078567A2 (en) * 2002-03-18 2003-09-25 Gamida-Cell Ltd. Methods of inducing differentiation in ex vivo expanded stem cells
IL164191A0 (en) * 2002-03-26 2005-12-18 Nanocyte Inc Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosme tic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue nanocyte inc.
US20040121442A1 (en) * 2002-05-05 2004-06-24 Ilan Chet Fungal chitinase, polynucleotide sequences encoding same, promoters of same, and uses thereof
ES2449115T3 (es) 2002-08-01 2014-03-18 Yeda Research And Development Co., Ltd. Método y composición para proteger el tejido neuronal de lesiones inducidas por niveles de glutamato elevados
US7267981B2 (en) 2002-10-07 2007-09-11 Technion Research & Development Foundation Ltd. Human foreskin fibroblasts for culturing ES cells
WO2004037204A2 (en) * 2002-10-25 2004-05-06 University Of South Florida Methods and compounds for disruption of cd40r/cd40l signaling in the treatment of alzheimer's disease
CA2504512A1 (en) 2002-10-30 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Molecules and methods using same for measuring non-transferrin bound iron
US20050054097A1 (en) * 2002-11-17 2005-03-10 Tony Peled EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
US7947499B2 (en) * 2002-11-29 2011-05-24 Technion Research & Development Foundation Ltd. Method of dynamically culturing embryonic stem cells
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
JP4676202B2 (ja) 2002-12-12 2011-04-27 アール．ビー．ティー （ラクト バイオ テクノロジーズ） リミテッド リグニンペルオキシオダーゼの製造方法ならびに皮膚および毛髪の明色化におけるその使用
PT2457999T (pt) 2002-12-16 2019-01-28 Technion Res & Dev Foundation Sistema de cultura para células estaminais pluripotentes
CN1780921B (zh) 2003-01-02 2010-12-08 拉帕波特家族医学研究院 用于检测触珠蛋白表型的试剂、试剂盒及其用途
ATE426575T1 (de) 2003-01-07 2009-04-15 Univ Ramot Peptidenanostrukturen die fremdmaterial enthalten,und verfahren zur herstellung derselben
EP2319857A3 (en) 2003-03-04 2012-06-27 Yeda Research And Development Co., Ltd. Pon polypeptides, polynucleotides encoding same and compositions and methods utilizing same
US8017113B2 (en) 2003-03-12 2011-09-13 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for diagnosing and treating an inflammation
EP1610678B1 (en) 2003-04-04 2011-07-27 Yeda Research And Development Co., Ltd. Antibodies for inhibiting the activity of mmp-2 and mmp-9
US8252588B2 (en) 2003-04-08 2012-08-28 Yeda Research And Development Co. Ltd. Stem cells having increased sensitivity to SDF-1 and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
AU2005234725B2 (en) * 2003-05-22 2012-02-23 Evogene Ltd. Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby
CN101942449B (zh) 2003-05-22 2014-07-02 伊沃基因有限公司 提高植物非生物胁迫耐受性和/或生物量的方法及用该方法所产生的植物
US7554007B2 (en) 2003-05-22 2009-06-30 Evogene Ltd. Methods of increasing abiotic stress tolerance and/or biomass in plants
US8129514B2 (en) * 2003-06-19 2012-03-06 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
WO2004111183A2 (en) * 2003-06-19 2004-12-23 Evogene Ltd. Plant trichome-specific promoter and leucoplast signal sequence
CA2530927A1 (en) 2003-06-30 2005-01-06 Tel Aviv University Future Technology Development L.P. Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
CN101076585A (zh) * 2003-08-14 2007-11-21 生物平衡公司 细菌株系、包括该细菌株系的组合物和其益生菌用途
US7625707B2 (en) 2003-10-02 2009-12-01 Ramot At Tel Aviv University Ltd. Antibacterial agents and methods of identifying and utilizing same
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
AU2004278175B2 (en) 2003-10-07 2010-11-04 Yeda Research And Development Co. Ltd. Antibodies to NIK, their preparation and use
JP2007508837A (ja) * 2003-10-23 2007-04-12 ファイザー・プロダクツ・インク 歯周疾患のためのワクチン
WO2005051423A2 (en) 2003-11-30 2005-06-09 Yeda Research And Development Co. Ltd Methods and agents for immune modulation and methods for identifying immune modulators
WO2005059100A2 (en) * 2003-12-12 2005-06-30 New York University Methods and compositions relating to cystatin c
US20100221233A1 (en) * 2003-12-15 2010-09-02 University Of South Florida Compositions and methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
WO2005061018A1 (en) 2003-12-22 2005-07-07 Regentis Biomaterials Ltd. Matrix comprising naturally-occurring protein backbone
US8007847B2 (en) * 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
US7423139B2 (en) 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
JP2007526337A (ja) 2004-03-02 2007-09-13 アクセルロン ファーマ インコーポレーテッド Ａｌｋ７およびミオスタチン阻害剤ならびにその使用
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
WO2005121364A2 (en) 2004-06-14 2005-12-22 Evogene Ltd. Polynucleotides and polypeptides involved in plant fiber development and methods of using same
US8680062B2 (en) * 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
WO2006006172A2 (en) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
WO2006030442A2 (en) * 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
EP2357241B1 (en) 2004-09-29 2015-03-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
WO2006035439A2 (en) * 2004-09-29 2006-04-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Recombinant human t2 rnase and uses thereof
US7781402B2 (en) * 2004-10-12 2010-08-24 Closed Loop Therapies Ltd. Methods and implantable devices for treating supraventricular arrhythmias
US20060134680A1 (en) * 2004-12-22 2006-06-22 Alexander Kotlyar Homogeneous populations of nucleic acids, methods of synthesyzing same and uses thereof
WO2006075335A2 (en) * 2005-01-16 2006-07-20 Zlango Ltd. Communications network system and methods for using same
US8375327B2 (en) * 2005-01-16 2013-02-12 Zlango Ltd. Iconic communication
WO2007080558A2 (en) * 2006-01-16 2007-07-19 Zlango Ltd. Communications network system and methods for using same
EP3028765B1 (en) 2005-01-31 2020-01-08 Realbio Technologies Ltd. Method of sequentially transferring liquids through a lateral flow capillary device
ATE511835T1 (de) 2005-02-17 2011-06-15 Hadasit Med Res Service Biophosphonate zur behandlung von endometriose
WO2006090388A2 (en) 2005-02-25 2006-08-31 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Fruit cell culture extract for treating inflammation
US7695927B2 (en) * 2005-03-18 2010-04-13 Detroit R & D Detection of hypertension using glucuronidated metabolic products
WO2006109312A2 (en) * 2005-04-15 2006-10-19 Vascular Biogenics Ltd. Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease
US8834862B2 (en) * 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
EP1888034A2 (en) 2005-05-26 2008-02-20 Yissum Research Development Company, of The Hebrew University of Jerusalem Compositions and methods using same for delivering agents into a target organ protected by a blood barrier
ES2524996T3 (es) 2005-06-16 2014-12-16 Ramot At Tel Aviv University Ltd. Células aisladas y poblaciones que comprenden a las mismas para el tratamiento de enfermedades del SNC
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
JP5383186B2 (ja) 2005-07-07 2014-01-08 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド Ｈ１９をダウンレギュレートする核酸薬剤、及びそれを使用する方法
US9051379B2 (en) 2005-07-07 2015-06-09 Fulcrum Sp Ltd. Sp1 polypeptides, modified Sp1 polypeptides and uses thereof
KR20080038131A (ko) 2005-07-18 2008-05-02 프로탈릭스 리미티드 생물학적으로 활성인 거대분자의 점막 또는 장관 투여
EP2889041A1 (en) 2005-07-26 2015-07-01 Rutgers, The State University of New Jersey Kit of reagents for tuberculosis assay
WO2007019541A2 (en) * 2005-08-08 2007-02-15 Onconon, Llc. Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US8916147B2 (en) 2005-08-24 2014-12-23 Yeda Research and Devolpment Co. Ltd. Universal donor-derived tolerogenic cells for inducing non-syngeneic transplantation tolerance
EP1962719A4 (en) 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd MEDIA FOR BREEDING STEM CELLS
JP2009508516A (ja) * 2005-09-22 2009-03-05 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム 核酸構築物、薬剤組成物、及び癌治療のためのその使用方法
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
RU2425151C2 (ru) 2005-10-24 2011-07-27 Эвоген Лтд. Изолированные полипептиды, кодирующие их полинуклеотиды, экспрессирующие их трансгенные растения и способы их использования
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
BRPI0620523A2 (pt) 2005-11-29 2011-11-16 Gamida Cell Ltd método de aumentar o potencial de implante e de atração celular, método de preparar células para transplante em um sujeito, população de células e composição farmacêutica
US8775526B2 (en) 2006-01-16 2014-07-08 Zlango Ltd. Iconic communication
US8759292B2 (en) 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
US8048848B2 (en) 2006-02-03 2011-11-01 Prolor Biotech Ltd. Long-acting interferons and derivatives thereof and methods thereof
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8476234B2 (en) 2006-02-03 2013-07-02 Prolor Biotech Inc. Long-acting coagulation factors and methods of producing same
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8450269B2 (en) 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US7553941B2 (en) 2006-02-03 2009-06-30 Modigene Inc Long-acting polypeptides and methods of producing same
CA2641079A1 (en) 2006-02-06 2007-08-16 Rappaport Family Institute For Research In The Medical Sciences Methods and kit for diagnosing t1dm
JP5107943B2 (ja) 2006-03-06 2012-12-26 ゼティク テクノロジーズ リミテッド 細胞の表現型を特定するための方法および組成物
CA2646384C (en) 2006-03-23 2020-03-24 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US20090226909A1 (en) 2006-03-28 2009-09-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for Determining Predisposition to Warfarin Resistance
MX2008012754A (es) * 2006-04-07 2009-04-27 Us Gov Health & Human Serv Composiciones de anticuerpos y metodos para tratamiento de enfermedad neoplastica.
EA200870555A1 (ru) * 2006-05-19 2009-04-28 Тева Фармасьютикал Индастриз, Лтд. Слитые белки, их применение и способы их получения
US20070281883A1 (en) * 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish
WO2008010228A2 (en) 2006-07-20 2008-01-24 Yeda Research And Development Co. Ltd. Photosyntheticorganisms and compositions and methods of generating same
US8809052B2 (en) 2006-08-28 2014-08-19 Yeda Research And Development Co. Ltd. Methods of generating mature oligodendrocytes
WO2008030865A1 (en) * 2006-09-08 2008-03-13 Wisconsin Alumni Research Foundation Assay for antibodies to mycobacterium paratuberculosis
US7888059B2 (en) * 2006-10-05 2011-02-15 Yeda Research And Development Co. Ltd. Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
WO2008041183A2 (en) 2006-10-05 2008-04-10 Technion Research & Development Foundation Ltd. Microtubes and methods of producing same
US20080131954A1 (en) * 2006-11-30 2008-06-05 Canon U.S. Life Sciences, Inc. Method of Separating Target DNA from Mixed DNA
AU2007335706B2 (en) 2006-12-20 2013-03-28 Evogene Ltd. Polynucleotides and polypeptides involved in plant fiber development and methods of using same
US7928083B2 (en) * 2007-01-16 2011-04-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem H19 silencing nucleic acid agents for treating rheumatoid arthritis
US20100196403A1 (en) * 2007-01-29 2010-08-05 Jacob Hochman Antibody conjugates for circumventing multi-drug resistance
EP2117616A2 (en) 2007-01-31 2009-11-18 Technion Research & Development Foundation Ltd. Electrospun scaffolds and methods of generating and using same
US8546333B2 (en) 2007-02-01 2013-10-01 Technion Research & Development Foundation Limited Albumin fibers and fabrics and methods of generating and using same
EP2839839B1 (en) 2007-02-28 2018-01-17 Yeda Research And Development Company Limited Nuclear targeting sequences
EP2144935A2 (en) 2007-03-29 2010-01-20 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
CN101702920B (zh) 2007-04-02 2013-03-13 特拉维夫大学拉莫特有限公司 癌细胞的检测方法及其在诊断和监测疾病治疗中的应用
MX341624B (es) 2007-04-09 2016-08-26 Evogene Ltd Polinucleotidos, polipeptidos y metodos para aumentar el contenido de aceite, la velocidad de crecimiento y biomasa de las plantas.
US9556210B2 (en) 2007-04-23 2017-01-31 Sabag-Rfa Ltd. System for delivering therapeutic agents into living cells and cells nuclei
US9156865B2 (en) 2007-04-23 2015-10-13 Deliversir Ltd System for delivering therapeutic agents into living cells and cells nuclei
WO2008129548A2 (en) * 2007-04-23 2008-10-30 Segev Laboratories Limited A system for delivering therapeutic agents into living cells and cells nuclei
EP2152905B1 (en) 2007-05-01 2015-12-02 Tel Hashomer Medical Research Infrastructure and Services Ltd. Methods and kits for detecting fetal cells in the maternal blood
DK3360571T3 (da) 2007-05-03 2021-01-04 Agency For Science Tech And Research Astarstar Antistoffer, der binder til et intracellulært PRL-1- eller PRL-3-polypeptid
CA2685701C (en) 2007-05-07 2019-01-15 Protalix Ltd. Large scale disposable bioreactor
EP2500428A3 (en) 2007-07-11 2012-12-26 Yeda Research and Development Co. Ltd. Nucleic acid construct systems capable of diagnosing or treating a cell state
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
EP2200628A2 (en) 2007-07-15 2010-06-30 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
CA2694481C (en) * 2007-07-24 2018-11-13 Evogene Ltd. Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance and/or biomass and/or yield in plants expressing same
HRP20150208T1 (hr) 2007-08-02 2015-06-05 Gilead Biologics, Inc. Lox i loxl2 inhibitori i njihove uporabe
WO2009022328A2 (en) 2007-08-15 2009-02-19 Yeda Research And Development Co. Ltd. Regulators of mmp-9 and uses therof
WO2009034574A2 (en) 2007-09-12 2009-03-19 Yeda Research And Development Co. Ltd. Methods of treating tumors in immune-privileged sites
KR20140107677A (ko) 2007-09-19 2014-09-04 플루리스템 리미티드 지방 또는 태반 조직 유래의 부착 세포 및 이의 치료 용도
US8088735B2 (en) 2007-10-19 2012-01-03 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
US8431158B2 (en) 2007-11-26 2013-04-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions comprising fibrous polypeptides and polysaccharides
CN101977928B (zh) 2007-12-27 2014-12-10 伊沃基因有限公司 用于改进植物的水分利用效率、肥料利用效率、生物/非生物胁迫耐受性、产量和生物量的分离多肽、多核苷酸
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US9297094B2 (en) 2008-02-21 2016-03-29 Technion Research & Development Foundation Ltd. Use of electrospun microtubes for drug delivery
US8153383B2 (en) * 2008-03-18 2012-04-10 Wisconsin Alumni Research Foundation Mycobacterial culture screening test for Mycobacterium avium complex bacteria
EP2280731A1 (en) * 2008-04-09 2011-02-09 Technion Research and Development Foundation, Ltd. Anti human immunodeficiency antibodies and uses thereof
US9132587B2 (en) * 2008-04-10 2015-09-15 Stratasys Ltd. System and method for three dimensional model printing
CN104491845A (zh) 2008-04-18 2015-04-08 科尔普兰特有限公司 产生和使用原胶原的方法
MX2010011511A (es) 2008-04-21 2011-06-09 Danziger Innovations Ltd Vectores de expresion viral de planta y uso de los mismos para generar variaciones genotipicas en genomas de plantas.
SG176464A1 (en) 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
TR201808744T4 (tr) * 2008-05-22 2018-07-23 Evogene Ltd İzole polinükleotidler ve polipeptidlerle bunların bitki yararını artırmaya yönelik kullanımına ilişkin yöntemler.
WO2009144720A1 (en) 2008-05-27 2009-12-03 Pluristem Ltd. Methods of treating inflammatory colon diseases
ES2688945T3 (es) 2008-05-28 2018-11-07 Ramot At Tel-Aviv University Ltd. Células madre mesenquimales para el tratamiento de enfermedades del SNC
CN102076415B (zh) 2008-06-29 2015-06-24 瑞尔比奥技术有限公司 尤其可用作生物测定过程中的捕捉装置的液体转移装置
GB2474807A (en) 2008-08-08 2011-04-27 Agency Science Tech & Res Vhz for diagnosis and treatment of cancers
US20120122800A1 (en) 2008-08-08 2012-05-17 Genisphere, LLC Hatfield, Pennsylvania Long-Acting DNA Dendrimers and Methods Thereof
WO2010020941A2 (en) 2008-08-18 2010-02-25 Evogene Ltd. Isolated polypeptides and polynucleotides useful for increasing nitrogen use efficiency, abiotic stress tolerance, yield and biomass in plants
CA2735790C (en) 2008-09-02 2017-02-28 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
US20110305682A1 (en) 2008-09-11 2011-12-15 Ben Gurion University Of The Negev Research And Development Authority Compositions and Methods for Treating S. Pneumonia Infection
EP2331679B1 (en) 2008-09-12 2017-04-19 Cryopraxis Criobiologia LTDA. Ischemic tissue cell therapy
EP2344521B1 (en) 2008-09-24 2019-08-21 Tel HaShomer Medical Research Infrastructure and Services Ltd. Peptides and compositions for prevention of cell adhesion and methods of using same
US20110178024A1 (en) 2008-09-29 2011-07-21 Ben Gurion University Of The Negev Research And Development Authority Amyloid beta-peptides and methods of use thereof
MX389590B (es) 2008-10-30 2025-03-20 Evogene Ltd Polinucleotidos y polipeptidos aislados y metodos para utilizarlos para aumentar el rendimiento de la planta, biomasa, tasa de crecimiento, vigor, contenido de aceite, tolerancia al estres abiotico de las plantas y eficacia en el uso de nitrogeno.
WO2010055525A1 (en) 2008-11-17 2010-05-20 Technion Research & Development Foundation Ltd. Method for predicting a patient's responsiveness to anti-folate therapy
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
WO2010061383A1 (en) 2008-11-26 2010-06-03 Biodalia Microbiological Technologies Ltd. A method of in-situ enrichment of foods with fructan
WO2010064231A1 (en) 2008-12-02 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods of analyzing a-i rna editing and nucleic acid constructs capable of same
US20120014927A1 (en) 2008-12-03 2012-01-19 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for determining predisposition to cancer
US8734759B2 (en) 2008-12-05 2014-05-27 Yeda Research And Development Co. Ltd. Methods of diagnosing and treating motor neuron diseases
WO2010071610A1 (en) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Severe chikungunya biomarkers
CA2748121C (en) 2008-12-29 2017-12-12 Tel Hashomer Medical Research, Infrastructure And Services Ltd. Peptides and compositions for prevention of cell adhesion and methods of using same
WO2010076788A2 (en) 2008-12-29 2010-07-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of predicting responsiveness to interferon treatment and treating hepatitis c infection
US8952218B2 (en) 2008-12-29 2015-02-10 Evogene Ltd. Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance, biomass and/or yield in plants expressing same
WO2010076794A1 (en) 2008-12-31 2010-07-08 Technion Research & Development Foundation Ltd. Method of denitrifying brine and systems capable of same
WO2010080769A2 (en) * 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
US8691760B2 (en) 2009-02-02 2014-04-08 Ramot At Tel-Aviv University Peptides, pharmaceutical compositions comprising same and uses thereof
WO2010089707A1 (en) 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy
EP2465920B1 (en) 2009-02-26 2017-04-12 Tel HaShomer Medical Research Infrastructure and Services Ltd. Isolated populations of renal stem cells and methods of isolating and using same
AU2010220157C1 (en) 2009-03-02 2015-08-06 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
HUE028729T2 (en) 2009-03-09 2017-01-30 Ramot At Tel-Aviv Univ Ltd Compositions for the prevention and treatment of neurodegenerative diseases
WO2010103517A1 (en) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Soluble compositions for the treatment of cxcr3-ligand associated diseases
EP2414542B1 (en) 2009-03-30 2017-08-30 Tel HaShomer Medical Research Infrastructure and Services Ltd. Methods of predicting clinical course and treating multiple sclerosis
JP2012522762A (ja) 2009-04-01 2012-09-27 ザ メディカル リサーチ， インフラストラクチャー， アンド ヘルス サーヴィシーズ ファンド オブ ザ テル アヴィヴ メディカル センター ケラチノサイトの増殖および分化を調節する方法
WO2010116375A1 (en) 2009-04-08 2010-10-14 Yeda Research And Development Co. Ltd. Isolated peptides for regulating apoptosis
SI2424896T1 (sl) 2009-04-30 2015-12-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Protitelesa anti-ceacam1 in postopki za njihovo uporabo
CN102576024B (zh) 2009-05-19 2016-10-26 泽蒂克科技有限公司 宫颈癌细胞和/或组织的鉴别染色的试剂盒和方法
WO2010137021A2 (en) 2009-05-27 2010-12-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of generating connective tissue
WO2010137013A1 (en) 2009-05-27 2010-12-02 Ramot At Tel Aviv University Ltd. Crystallized photosystem i units from the pea plant and their use in solid state devices
WO2010137017A2 (en) 2009-05-27 2010-12-02 Yeda Research And Development Co. Ltd. Proteasome inhibitors and uses thereof
EP2435078A1 (en) 2009-05-28 2012-04-04 Yeda Research and Development Co. Ltd. Methods of treating inflammation
ES2773985T3 (es) 2009-06-10 2020-07-16 Evogene Ltd Polinucleótidos y polipéptidos aislados, y métodos para usar los mismos para incrementar la eficiencia en el uso de nitrógeno, rendimiento, tasa de crecimiento, vigor, biomasa, contenido de aceite, y/o tolerancia al estrés abiótico
EP2446267A1 (en) 2009-06-24 2012-05-02 Health Corporation - Rambam Methods and kits for isolating placental derived microparticles and use of same for diagnosis of fetal disorders
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
US20120122122A1 (en) 2009-07-21 2012-05-17 Tel Hashomer Medical Research Infrastructure And Services Ltd. Method of diagnosing cancer
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
US20120148546A1 (en) 2009-08-17 2012-06-14 Technion Research & Development Foundation Ltd. Pericyte progenitor cells and methods of generating and using same
WO2011022710A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc Therapeutic methods and compositions
MX2012002189A (es) 2009-08-21 2012-03-16 Beeologics Inc Prevencion y cura de las enfermedades de los insectos beneficiosos a traves de moleculas.
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
RU2012110585A (ru) * 2009-08-21 2013-09-27 Джилид Байолоджикс, Инк. Каталичические домены лизилоксидазы и loxl2
MX2012002269A (es) * 2009-08-21 2012-07-20 Gilead Biologics Inc Metodos y composiciones para el tratamiento de trastornos fibroticos pulmonares.
WO2011022709A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vitro screening assays
CN102596179A (zh) 2009-08-27 2012-07-18 工业研究与发展基金会有限公司 脂质体组合物及其用途
EP2475381A2 (en) 2009-09-08 2012-07-18 Yeda Research and Development Co. Ltd. Methods for hematopoietic precursor mobilization
EP2475784A1 (en) 2009-09-08 2012-07-18 Ramot at Tel-Aviv University Ltd. Methods of diagnosing amyotrophic lateral sclerosis (als)
WO2011030329A1 (en) 2009-09-10 2011-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating tumors
WO2011033506A2 (en) 2009-09-17 2011-03-24 Yeda Research And Development Co. Ltd. Isolated pon1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
JP2013505230A (ja) 2009-09-17 2013-02-14 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド 酸化ストレス関連障害を処置するためのペプチド
US8735124B2 (en) 2009-09-17 2014-05-27 Yeda Research And Development Co. Ltd. Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
CA2777448C (en) 2009-10-14 2023-02-28 Ilan Sela Compositions for controlling varroa mites in bees
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
EP2488209B1 (en) 2009-10-16 2016-09-28 Rutgers, the State University of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
US9476060B2 (en) 2009-10-21 2016-10-25 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
IL201999A (en) 2009-11-08 2017-10-31 Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel A knockout mouse of the 1 – mo gene, a gene associated with morbidly extreme obesity
US8962561B2 (en) 2009-11-12 2015-02-24 Ramot At Tel-Aviv University Ltd. Compositions comprising PEDF and uses of same in the treatment and prevention of ovary-related syndromes
CA3174901A1 (en) 2009-11-12 2011-05-19 Technion Research & Development Foundation Ltd. Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
WO2011058555A1 (en) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. A method of editing dna in a cell and constructs capable of same
WO2011061736A1 (en) 2009-11-17 2011-05-26 Protalix Ltd. Alkaline alpha galactosidase for the treatment of fabry disease
US20120273993A1 (en) 2009-11-24 2012-11-01 Collplant Ltd. Method of generating collagen fibers
ES2553712T3 (es) 2009-11-30 2015-12-11 Pluristem Ltd. Células adherentes de la placenta y uso de las mismas en el tratamiento de enfermedad
US9562235B2 (en) 2009-12-06 2017-02-07 A.B. Seeds Ltd. MicroRNA compositions and methods for enhancing plant resistance to abiotic stress
WO2011072091A1 (en) 2009-12-09 2011-06-16 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the cns
BR112012016033B1 (pt) 2009-12-28 2021-03-09 Evogene Ltd. métodos de aumento de produção de semente, biomassa, taxa de crescimento, vigor, tolerância à deficiência de nitrogênio, eficiência no uso de nitrogênio e/ou redução do tempo de florescimento de uma planta, e, para produzir uma planta transgênica
EP2519239B1 (en) 2009-12-29 2017-03-08 Gamida Cell Ltd. Methods for enhancing natural killer cell proliferation and activity
EP2521776B1 (en) 2010-01-05 2016-11-02 Vascular Biogenics Ltd. Methods for use of a specific anti-angiogenic adenoviral agent
US20130052165A1 (en) 2010-01-12 2013-02-28 Livnat Bangio Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby
EP2528949A1 (en) 2010-01-27 2012-12-05 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
JP6134142B2 (ja) 2010-02-04 2017-05-24 ギリアド バイオロジクス, インク.Gilead Biologics, Inc. リシルオキシダーゼ様２（ｌｏｘｌ２）に結合する抗体及びその使用方法
US9410131B2 (en) 2010-02-11 2016-08-09 Yeda Research And Development Co. Ltd. Enzymatic systems for carbon fixation and methods of generating same
EP2538961B1 (en) 2010-02-24 2016-10-12 Ben Gurion University Of The Negev Research And Development Authority Inhibition of necrosis
WO2011107939A1 (en) 2010-03-01 2011-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of predicting efficacy of an anti-vegfa treatment for solid tumors
WO2011107994A1 (en) 2010-03-04 2011-09-09 Yeda Research And Development Co. Ltd. Methods of measuring protein stability
NZ627060A (en) 2010-03-08 2016-01-29 Monsanto Technology Llc Polynucleotide molecules for gene regulation in plants
US9267142B2 (en) 2010-03-08 2016-02-23 Yeda Research And Development Co. Ltd. Recombinant protein production in heterologous systems
WO2011111050A2 (en) 2010-03-11 2011-09-15 Jacob Edrei Methods of generating hydrogen
WO2011125015A2 (en) 2010-04-05 2011-10-13 Bar-Ilan University Protease-activatable pore-forming polypeptides
EP2557913B1 (en) 2010-04-12 2016-08-03 Ben Gurion University Of The Negev Research And Development Authority Sulfotransferase of a red microalga and uses thereof
US8927274B2 (en) 2010-04-12 2015-01-06 Technion Research & Development Foundation Limited Populations of pancreatic progenitor cells and methods of isolating and using same
CA2792826A1 (en) 2010-04-18 2011-10-27 Yeda Research And Development Co. Ltd. Molecules and methods of using same for treating erbb/erbb ligands associated diseases
MX395168B (es) 2010-04-28 2025-03-19 Evogene Ltd Polinucleotidos y polipeptidos aislados, y metodos para utilizarlos para mejorar el rendimiento de la planta y/o las caracteristicas agricolas.
US20130053277A1 (en) 2010-05-04 2013-02-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of identifying inhibitors of polypeptides-of-interest
WO2011138785A2 (en) 2010-05-05 2011-11-10 Rappaport Family Institute For Research In The Medical Sciences Use of ccl1 in therapy
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
WO2011141914A1 (en) 2010-05-13 2011-11-17 Tel Hashomer Medical Research Infrastructure And Services Ltd. Isolated populations of adult renal cells and methods of isolating and using same
US9624285B2 (en) 2010-06-03 2017-04-18 Ramot a Tel-Aviv University Ltd. Methods of treating diabetes and compositions capable of same
AU2011263306A1 (en) 2010-06-07 2013-01-10 Osnat Ashur-Fabian Methods and kits for diagnosing conditions related to hypoxia
WO2011158243A2 (en) 2010-06-16 2011-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of diagnosing and treating cancer
BR112012032126A2 (pt) 2010-06-16 2017-10-17 Futuragene Israel Ltd Empresa Isralense polinucleotídeo isolado, estrutura de ácido nucléico, sistema de estrutura de ácido nucléico, polipeptídeo isolado, planta, composição inseticida, e método para controlar ou exterminar um inseto
WO2012007945A2 (en) 2010-07-12 2012-01-19 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Isolated polynucleotides and methods and plants using same for regulating plant acidity
JP2013535963A (ja) 2010-07-15 2013-09-19 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド Ｍｈｃクラスｉｉと糖尿病関連自己抗原性ペプチドとの天然型複合体に対するｔ細胞受容体様特異性を有する単離された高親和性実体
CA2804728A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Nucleic acid construct for increasing abiotic stress tolerance in plants
WO2012007951A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and glutamic acid decarboxylase (gad) autoantigenic peptides
WO2012011113A2 (en) 2010-07-22 2012-01-26 Shai Yarkoni Regulatory immune cells with enhanced targeted cell death effect
US20130130387A1 (en) 2010-07-27 2013-05-23 Technion Research & Development Foundation Limited Method for generating induced pluripotent stem cells from keratinocytes derived from plucked hair follicles
WO2012014205A1 (en) 2010-07-27 2012-02-02 Technion Research & Development Foundation Ltd. Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
WO2012014208A2 (en) 2010-07-27 2012-02-02 Yeda Research And Development Co. Ltd. Methods and systems for assessing clonality of cell cultures
US8901074B2 (en) 2010-08-04 2014-12-02 Ramot At Tel-Aviv University Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases
WO2012025914A1 (en) 2010-08-22 2012-03-01 Ramot At Tel-Aviv University Ltd. Induced pluripotent stem cells derived from human pancreatic beta cells
WO2012025925A1 (en) 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Methods of improving transplantation using sdf-1alpha
BR112013004851A2 (pt) 2010-08-30 2016-06-07 Evogene Ltd método de aumento de eficiência do uso de nitrogênio, rendimento, biomassa, taxa de crescimento, vigor, conteúdo de óleo, rendimento da fibra e/ou tolerância ao estresse abiótico de uma planta, polinucleotídeo isolado, estrutura de ácido nucleio, polipeptídeo isolado, célula vegetal e planta transgêncica
WO2012032510A1 (en) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Primers for amplifying dna and methods of selecting same
US20130164288A1 (en) 2010-09-07 2013-06-27 Protalix Ltd. Readthrough acetylcholinesterase (ache-r) for treating or preventing parkinson's disease
WO2012032519A2 (en) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of diagnosing parkinson's disease
DK2614141T3 (da) 2010-09-07 2019-09-09 Technion Res & Dev Foundation Hidtil ukendte fremgangsmåder og dyrkningsmedier til dyrkning af pluripotente stamceller
CN103270050A (zh) 2010-09-08 2013-08-28 耶达研究及发展有限公司 用于稳定和长期移植的免疫抑制药物组合
CA2810632C (en) 2010-09-08 2020-06-02 Yeda Research And Development Co. Ltd. Use of anti third party central memory t cells for anti-leukemia/lymphoma treatment
EP2616539A1 (en) 2010-09-15 2013-07-24 Ramot at Tel-Aviv University Ltd. Methods of expanding and redifferentiating islet beta cells
WO2012038956A1 (en) 2010-09-20 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating neurodegenerative diseases
WO2012052872A2 (en) 2010-10-17 2012-04-26 Yeda Research And Development Co. Ltd. Methods and compositions for the treatment of insulin-associated medical conditions
WO2012052878A1 (en) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Isolated polynucleotides and nucleic acid constructs for directing expression of a gene-of-interest in cells
US20130216603A1 (en) 2010-10-27 2013-08-22 Nanocyte (Israel) Ltd. Pharmaceutical compositions and delivery devices comprising stinging cells or capsules
EP2632956B1 (en) 2010-10-28 2018-06-20 Yeda Research and Development Co. Ltd. Methods of generating antibodies to metalloenzymes
BR112013010825A2 (pt) 2010-11-03 2019-09-24 Futuragene Israel Ltda plantas transgênicas com rendimentos melhorados de sacarificação e métodos para geração das mesmas
US9410132B2 (en) 2010-11-04 2016-08-09 Ben-Gurion University Of The Negev Research And Development Authority Acyl-CoA: diacylglycerol acyltransferase 1-like gene (PtDGAT1) and uses thereof
AU2011330768A1 (en) 2010-11-15 2013-05-30 Merz Pharma Gmbh & Co. Kgaa Dipeptide analogs for treating conditions associated with amyloid fibril formation
EP2640404B1 (en) 2010-11-17 2017-02-22 Ben Gurion University of The Negev Research and Development Authority T-cell therapy to neurodegenerative diseases
JP6139410B2 (ja) 2010-12-02 2017-05-31 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド 角膜細胞の作製方法および該角膜細胞を含む細胞集団
AU2011253984A1 (en) 2010-12-07 2012-06-28 Biobalance Llc Method For Identifying E. Coli M-17
EP2652125B1 (en) 2010-12-15 2017-04-26 Kadimastem Ltd. Insulin producing cells derived from pluripotent stem cells
AU2011346525B2 (en) 2010-12-22 2016-04-28 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for improving plant properties
AU2011350620B2 (en) 2010-12-28 2017-03-02 Kamedis Ltd. Plant extracts for the treatment and prevention of infections
ES2774190T3 (es) 2011-01-20 2020-07-17 Protalix Ltd Composiciones de alfa-galactosidasa
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
WO2012114339A1 (en) 2011-02-23 2012-08-30 Rappaport Family Institute For Research In The Medical Sciences High affinity molecules capable of binding a type a plexin receptor and uses of same
CN103597078B (zh) 2011-03-02 2016-12-14 富途锐基尼以色列有限公司 具有功能失调的t3ss蛋白的抗菌性转基因植物
WO2012117373A1 (en) 2011-03-03 2012-09-07 Ramot At Tel-Aviv University Ltd. Genetically modified muscle cells which express neurotrophic factors
CN109797138A (zh) 2011-03-06 2019-05-24 默克雪兰诺有限公司 低岩藻糖细胞系及其应用
WO2012120518A1 (en) 2011-03-08 2012-09-13 Ramot At Tel-Aviv University Ltd. Compositions and methods for diagnosing and treating phenylketonuria (pku)
WO2012123938A1 (en) 2011-03-17 2012-09-20 Tel Hashomer Medical Research Infrastructure And Services Ltd. Quinolone analogs for treating autoimmune diseases
CN103429619B (zh) 2011-03-17 2017-07-28 雷蒙特亚特特拉维夫大学有限公司 双特异性和单特异性、不对称抗体和其制备方法
EP3260533B1 (en) 2011-03-22 2019-09-11 Pluristem Ltd. Methods for treating radiation or chemical injury
BR112013024323A2 (pt) 2011-03-24 2017-06-13 Neurim Pharmaceuticals ( 1991 ) Ltd peptídeos neuroprotetores
WO2012131680A2 (en) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions and methods for treating inflammation
WO2012137202A1 (en) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci)
JP5990254B2 (ja) 2011-04-06 2016-09-07 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． 代謝活性プロフィルのモニタリング方法および分析方法ならびにそれらの診断使用および治療使用
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
CA2832812C (en) 2011-04-15 2017-12-05 Pluristem Ltd. Methods and systems for harvesting cells
AR086243A1 (es) 2011-05-03 2013-11-27 Evogene Ltd Polipeptidos y polinucleotidos aislados y metodos para su uso, para aumentar el rendimiento, la biomasa, el indice de crecimiento, el vigor, el contenido de aceite, la tolerancia al estres abiotico de las plantas y la eficiencia en el uso del nitrogeno
WO2012150600A2 (en) 2011-05-04 2012-11-08 Ramot At Tel-Aviv University Ltd. Regulation of amyloid beta molecular composition for the treatment of alzheimer's disease
WO2012153333A1 (en) 2011-05-09 2012-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Regeneration and repair of mesenchymal tissue using amelogenin
WO2012153336A2 (en) 2011-05-12 2012-11-15 Rakuto Bio Technologies Ltd. Methods and device for lightening skin complexion
WO2012156976A1 (en) 2011-05-16 2012-11-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of producing artemisinin in non-host plants and vectors for use in same
WO2012160526A2 (en) 2011-05-23 2012-11-29 Ofir Menashe Formulations of microorganism comprising particles and uses of same
WO2012160563A2 (en) 2011-05-23 2012-11-29 Yeda Research And Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
CN104039812A (zh) 2011-05-31 2014-09-10 和黄生物膜医疗解决方案有限公司 细胞聚集体的分散和脱离
WO2012164565A1 (en) 2011-06-01 2012-12-06 Yeda Research And Development Co. Ltd. Compositions and methods for downregulating prokaryotic genes
US10166295B2 (en) 2011-06-02 2019-01-01 Opko Biologics Ltd. Pegylated OXM variants
EP2720720B1 (en) 2011-06-14 2018-02-28 Yeda Research and Development Co. Ltd. Combination therapy to prevent dcis formation and progression to breast cancer
MX2014000180A (es) 2011-06-23 2014-03-27 Kaiima Bio Agritech Ltd Trigo comun, sus plantas o partes que tienen un genoma parcial o completamente multiplicado, sus hibridos y productos y metodos para generarlos y utilizarlos.
CN103929950A (zh) 2011-07-20 2014-07-16 凯伊玛生物农业科技有限公司 具有部分或完全倍增基因组的玉米植物及其用途
US20130030452A1 (en) 2011-07-27 2013-01-31 Health Corporation - Rambam Devices for surgical applications
US9150858B2 (en) 2011-08-04 2015-10-06 Yeda Research And Development Co. Ltd. Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
EP2741753A2 (en) 2011-08-09 2014-06-18 Yeda Research and Development Co. Ltd. Downregulation of mir-7 for promotion of beta cell differentiation and insulin production
EP2741602A1 (en) 2011-08-14 2014-06-18 Kaiima Bio Agritech Ltd. Durum wheat plants having a partially or fully multiplied genome and uses thereof
US9959392B2 (en) 2011-09-07 2018-05-01 Yeda Research And Development Co. Ltd. Olfactory signature and odorant mixture having the same
US20140212398A1 (en) 2011-09-08 2014-07-31 Yeda Research And Development Co. Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
CN103890195A (zh) 2011-09-08 2014-06-25 耶达研究及发展有限公司 用于肺癌的新型风险生物标志物
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
CN107739737A (zh) 2011-09-13 2018-02-27 孟山都技术公司 用于杂草控制的方法和组合物
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
EP2756086B1 (en) 2011-09-13 2018-02-21 Monsanto Technology LLC Methods and compositions for weed control
BR112014005975A8 (pt) 2011-09-13 2017-09-12 Monsanto Technology Llc Método de controle de planta, método de redução de expressão de um gene pds em uma planta, cassete de expressão microbiana, método de fazer um polinucleotídeo, método de identificação de polinucleotídeos, e composições para controle de erva daninha
US9416363B2 (en) 2011-09-13 2016-08-16 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
WO2013054320A1 (en) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
CA2852758C (en) 2011-10-21 2020-12-29 Augurex Life Sciences Corporation Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis
US9145559B2 (en) 2011-10-27 2015-09-29 Yeda Research And Development Co. Ltd. Methods of treating cancer
CN103917647B (zh) 2011-11-03 2020-07-10 夸克制药公司 用于神经保护的方法和组合物
WO2013070821A1 (en) 2011-11-08 2013-05-16 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the nervous system
US9736998B2 (en) 2011-11-23 2017-08-22 Danziger Dan Flower Farm Otomeria plants
US9617331B2 (en) 2011-11-27 2017-04-11 Yeda Research And Development Co. Ltd. Methods of regulating angiogenesis by administering agents which increase apoB-100 polypeptide
AU2012348574A1 (en) 2011-12-08 2014-07-24 Yeda Research And Development Co. Ltd. Mammalian fetal pulmonary cells and therapeutic use of same
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
IN2014MN01467A (cs) 2011-12-22 2015-05-01 Yeda Res & Dev
CN104254395B (zh) 2011-12-22 2016-05-04 生命科技公司 用于分析物测定的序贯侧向流动毛细管装置
AU2012359984A1 (en) 2011-12-28 2014-07-10 Kaiima Bio Agritech Ltd. Cultivated sorghum plant having a partially or fully multiplied genome and uses of same
CN104080480A (zh) 2012-01-01 2014-10-01 奇比艾企业有限公司 用于选择性递送治疗剂和诊断剂的endo180靶向微粒
WO2013114363A2 (en) 2012-01-30 2013-08-08 Yeda Research And Development Co.Ltd. Antimicrobial agents
US20150010527A1 (en) 2012-02-01 2015-01-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
US10184131B2 (en) 2012-02-06 2019-01-22 A.B. Seeds Ltd. Isolated polynucleotides expressing or modulating microRNAs or targets of same, transgenic plants comprising same and uses thereof
SG11201404608WA (en) 2012-02-13 2014-09-26 Gamida Cell Ltd Mesenchymal stem cells conditioned medium and methods of generating and using the same
KR102630953B1 (ko) 2012-02-14 2024-01-29 옵코 바이오로직스 리미티드 장기 작용 응고 인자들 및 이를 생산하는 방법들
WO2013121405A1 (en) 2012-02-19 2013-08-22 Protalix Ltd. Oral unit dosage forms and uses of same for the treatment of gaucher disease
WO2013124816A2 (en) 2012-02-22 2013-08-29 Brainstem Biotec Ltd. Generation of neural stem cells and motor neurons
JP6329911B2 (ja) 2012-02-22 2018-05-23 ブレインステム バイオテック リミテッド 星状膠細胞作製のためのミクロｒｎａ
EP2833714A1 (en) 2012-03-01 2015-02-11 The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Male sterile garlic plants, hybrid offspring of same and methods of generating and using same
CN104411724B (zh) 2012-03-07 2018-08-31 耶达研究及发展有限公司 抑制静止素巯基氧化酶(qsox1)的组合物及其用途
US9334308B2 (en) 2012-03-22 2016-05-10 Ramot At Tel-Aviv University Ltd. PLIF multimeric peptides and uses thereof
JP2015514746A (ja) 2012-04-18 2015-05-21 ラモット アット テル アビブ ユニバーシティ， リミテッド 核酸を送達するための脂質化グリコサミノグリカン粒子
WO2013157002A1 (en) 2012-04-19 2013-10-24 Prolor Biotech Inc. Long-acting oxyntomodulin variants and methods of producing same
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
JP6181158B2 (ja) 2012-05-09 2017-08-16 イェダ リサーチ アンド デベロップメント カンパニー リミテッド ＴＮＦ−α阻害剤としてのＴＡＣＥプロドメインの変異体およびその医学的使用
US8865158B2 (en) 2012-05-22 2014-10-21 Ramot At Tel-Aviv University Ltd. Bacteriophages for reducing toxicity of bacteria
CA2873828A1 (en) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Naked dsrna for silencing target molecules in plant seeds
KR101937733B1 (ko) 2012-05-24 2019-01-11 마운트게이트 그룹 리미티드 광견병 감염의 방지 및 치료에 관한 조성물 및 방법
EP2855507B1 (en) 2012-06-03 2018-01-03 Ben-Gurion University of The Negev Research and Development Authority Functionalized titanium binding peptides and implants coated with same
EP2854838B1 (en) 2012-06-04 2018-10-17 OPKO Biologics Ltd. Pegylated oxm variants
US10023474B2 (en) 2012-07-03 2018-07-17 Nanospun Technologies Ltd. Methods for adsorption and biodegradation of petroleum
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
DK2880155T3 (da) 2012-07-29 2019-07-15 Yeda Res & Dev Anvendelse af den reduktive glycinvej til generering af formatotrofiske og autotrofiske mikroorganismer
CN104684558A (zh) 2012-07-31 2015-06-03 耶达研究及发展有限公司 诊断和治疗运动神经元疾病的方法
JP6362596B2 (ja) 2012-08-06 2018-07-25 ブレインストーム セル セラペウティクス リミテッド 神経栄養因子を分泌する間葉系幹細胞の作製方法
WO2014033723A1 (en) 2012-09-03 2014-03-06 A.B. Seeds Ltd. Method of improving abiotic stress tolerance of plants and plants generated thereby
EP2895197B1 (en) 2012-09-12 2020-02-26 Ramot at Tel-Aviv University Ltd. Immunoparticles and methods of generating and using same
WO2014057490A1 (en) 2012-10-09 2014-04-17 Ramot At Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
EP2908864B1 (en) 2012-10-22 2019-12-11 Sabag-Rfa Ltd. Phosphate compounds for delivering therapeutic agents into living cells and cells nuclei
EP3584259A1 (en) 2012-10-24 2019-12-25 Yeda Research and Development Co., Ltd. Combinations of epidermal growth factor receptor targeting antibodies for treating cancer
WO2014068553A1 (en) 2012-10-29 2014-05-08 Yeda Research And Development Co. Ltd. Aptamers, multimeric aptamers and uses thereof
AU2013349239B2 (en) 2012-11-20 2018-04-12 Opko Biologics Ltd. Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
JP2016502536A (ja) 2012-11-29 2016-01-28 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 腫瘍転移を防止し、がんを処置および予後診断し、推定転移阻害剤である薬剤を同定する方法
WO2014106837A2 (en) 2013-01-01 2014-07-10 A. B. Seeds Ltd. ISOLATED dsRNA MOLECULES AND METHODS OF USING SAME FOR SILENCING TARGET MOLECULES OF INTEREST
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
WO2014108850A2 (en) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. High throughput transcriptome analysis
WO2014108854A1 (en) 2013-01-09 2014-07-17 Fusimab Ltd. Monospecific anti-hgf and anti-ang2 antibodies and bispecific anti-hgf/anti-ang2 antibodies
CA2894472C (en) 2013-01-17 2021-08-17 Novellusdx Ltd. Methods and systems for identifying patient specific driver mutations
US10000737B2 (en) 2013-02-04 2018-06-19 Ramot At Tel-Aviv University Ltd. Generation of cytotoxic tumor specific cell lines and uses thereof
WO2014136113A1 (en) 2013-03-06 2014-09-12 Protalix Ltd. Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
EP2964669B1 (en) 2013-03-06 2018-09-12 Protalix Ltd. Use of plant cells expressing a tnfalpha polypeptide inhibitor in therapy
CN105263329B (zh) 2013-03-13 2020-09-18 孟山都技术公司 用于杂草控制的方法和组合物
US10609930B2 (en) 2013-03-13 2020-04-07 Monsanto Technology Llc Methods and compositions for weed control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
CN105263511A (zh) 2013-03-21 2016-01-20 科尔普兰特有限公司 用于组织再生的包含胶原和prp的组合物
US20160051693A1 (en) 2013-03-21 2016-02-25 Genisphere, Llc Cellular Delivery of DNA Intercalating Agents
AU2014240733B2 (en) 2013-03-24 2018-11-22 Biolinerx Ltd. Methods of treating myeloid leukemia
WO2014174511A1 (en) 2013-04-21 2014-10-30 Yeda Research And Development Co. Ltd. Agents for downregulation of the activity and/or amount of bcl-xl and/or bcl-w
CN105531365A (zh) 2013-04-23 2016-04-27 耶达研究及发展有限公司 分离的幼稚多能干细胞和产生所述细胞的方法
ES2671002T3 (es) 2013-04-25 2018-06-04 Yeda Research And Development Co., Ltd. Uso de péptidos inhibidores para el tratamiento de enfermedades inflamatorias
EP2999717B1 (en) 2013-05-21 2018-08-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Treatment of mast cell related pathologies
HRP20192284T1 (hr) 2013-05-27 2020-03-06 Rakuto Bio Technologies Ltd. Kozmetički sastavi koji sadrže enzimski sustav
WO2014207744A1 (en) 2013-06-24 2014-12-31 Ramot At Tel-Aviv University Ltd. Omentum based scaffold and delivery system
CN105980567B (zh) 2013-07-19 2021-04-16 孟山都技术有限公司 用于控制叶甲属的组合物和方法
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015015489A1 (en) 2013-07-30 2015-02-05 Biolinerx Ltd. Antibody for treating diabetes and autoimmune diseases
CN105849117B (zh) 2013-08-29 2017-12-12 耶达研究及发展有限公司 Na,K‑ATP酶的α2亚型的选择性抑制剂和用于降低眼内压的用途
IL228284A (en) 2013-09-03 2016-12-29 Technion Res & Dev Foundation Implants from cellular scaffolding and blood vessel stalk
US20160251410A1 (en) 2013-09-03 2016-09-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for expressing recombinant polypeptides
WO2015033344A1 (en) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and kits for inhibiting pathogenicity of group a streptococcus (gas) or group g streptococcus (ggs)
WO2015037009A1 (en) 2013-09-16 2015-03-19 Plexicure Ltd. Isolated proteins capable of binding plexin-a4 and methods of producing and using same
WO2015040609A1 (en) 2013-09-17 2015-03-26 Yeda Research And Development Co. Ltd. Erk-derived peptides and uses thereof
AU2014330807B2 (en) 2013-10-01 2020-07-02 Kadimastem Ltd. Directed differentiation of astrocytes from human pluripotent stem cells for use in drug screening and the treatment of Amyotrophic Lateral Sclerosis (ALS)
EP3060239B1 (en) 2013-10-21 2020-05-13 OPKO Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
WO2015059690A1 (en) 2013-10-24 2015-04-30 Yeda Research And Development Co. Ltd. Polynucleotides encoding brex system polypeptides and methods of using s ame
US20160243187A1 (en) 2013-10-31 2016-08-25 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
ES3008698T3 (en) 2013-11-04 2025-03-24 Greenlight Biosciences Inc Compositions and methods for controlling arthropod parasite and pest infestations
EP3074044A2 (en) 2013-11-28 2016-10-05 Yeda Research and Development Co., Ltd. Synaptojanin-2 inhibitors and uses thereof
ES2754207T3 (es) 2013-11-28 2020-04-16 Tel Hashomer Medical Res Infrastructure & Services Ltd Inhibidores de la ARN polimerasa I y usos de los mismos
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
ES2697757T3 (es) 2013-12-10 2019-01-28 Yeda Res & Dev Uso de enzimas que catalizan la síntesis de piruvato a partir de formiato y acetil-CoA y bacterias que expresan la misma
BR112016016337A2 (pt) 2014-01-15 2017-10-03 Monsanto Technology Llc Composição e métodos para controlar crescimento, desenvolvimento ou a capacidade de reprodução de uma planta, e para sensibilizar uma planta para um herbicida inibidor de epsps
US20160340659A1 (en) 2014-01-30 2016-11-24 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same
CA2937992A1 (en) 2014-02-03 2015-08-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of eliminating stem cells
US10125365B2 (en) 2014-02-05 2018-11-13 Yeda Research And Development Co. Ltd. Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
US10066014B2 (en) 2014-02-06 2018-09-04 Yeda Research And Development Co. Ltd. Anti CD84 antibodies, compositions comprising same and uses thereof
US20170101633A1 (en) 2014-02-10 2017-04-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
EP3105587B1 (en) 2014-02-11 2023-09-06 Brainstorm Cell Therapeutics Ltd. Method of qualifying cells
US20170067894A1 (en) 2014-03-03 2017-03-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method and device for detection of pseudomonas aeruginosa
EP2923709A1 (en) 2014-03-28 2015-09-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Multi-component-multistage malaria vaccine
BR112016022711A2 (pt) 2014-04-01 2017-10-31 Monsanto Technology Llc composições e métodos para controle de pragas de inseto
EP3129075B1 (en) 2014-04-10 2024-09-18 Bonus Therapeutics Ltd. Bone repair compositions
DK3643795T3 (da) 2014-04-14 2022-05-09 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Fremganffremgangsmåde til bestemmelse af celle- eller vævsdød ved analyse af dna-methylering
ES2764504T3 (es) 2014-04-17 2020-06-03 Yeda Res & Dev Métodos y equipos para analizar restos de unión al ADN fijados al ADN
CA2946262C (en) 2014-04-27 2022-07-26 Ccam Biotherapeutics Ltd. Humanized antibodies against ceacam1
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
ES2870658T3 (es) 2014-04-28 2021-10-27 Yeda Res & Dev Respuesta del microbioma a agentes
CA2945736A1 (en) 2014-05-04 2015-11-12 Forrest Innovations Ltd. Compositions for mosquito control and uses of same
EP3145947B1 (en) 2014-05-22 2025-02-12 Yeda Research and Development Co., Ltd. Recombinant microorganisms capable of carbon fixation
EP3149155B1 (en) 2014-06-02 2020-09-23 Kadimastem Ltd. Methods of inducing myelination and maturation of oligodendrocytes
US20170253881A1 (en) 2014-06-02 2017-09-07 Technion Research & Development Foundation Limited Compositions and methods of selectively inhibiting irp1 and treating inflammation
US10988764B2 (en) 2014-06-23 2021-04-27 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
EP3145951A1 (en) 2014-06-24 2017-03-29 InSight Biopharmaceuticals Ltd. Methods of purifying antibodies
ES2791199T3 (es) 2014-06-25 2020-11-03 Tel Hashomer Medical Res Infrastructure & Services Ltd Identificación de marcadores de células madre cancerosas y uso de los mismos para diagnóstico y tratamiento
EP3161138A4 (en) 2014-06-25 2017-12-06 Monsanto Technology LLC Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
US10583084B2 (en) 2014-06-26 2020-03-10 Ramot At Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids
WO2016005985A2 (en) 2014-07-09 2016-01-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming cells
AU2015291151B2 (en) 2014-07-15 2019-10-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Isolated polypeptides of CD44 and uses thereof
EP3172340B1 (en) 2014-07-21 2019-02-20 Novellusdx Ltd. Methods for determining drug response of patient specific mutations
CA2955414A1 (en) 2014-07-21 2016-01-28 Novellusdx Ltd. Methods and systems for determining oncogenic index of patient specific mutations
RU2021123470A (ru) 2014-07-29 2021-09-06 Монсанто Текнолоджи Ллс Композиции и способы борьбы с насекомыми-вредителями
JP2017525351A (ja) 2014-07-30 2017-09-07 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． 多能性幹細胞の培養用培地
CN107076746B (zh) 2014-08-14 2020-05-29 米密德诊断学有限公司 使用流形和超平面进行生物学数据的计算机分析
WO2016030899A1 (en) 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral scleroses
EP2992895A1 (en) 2014-09-08 2016-03-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Three-component-multistage malaria vaccine
WO2016038609A1 (en) 2014-09-08 2016-03-17 Yeda Research And Development Co. Ltd. Anti-her3 antibodies and uses of same
EP3191523B1 (en) 2014-09-08 2019-08-07 Yeda Research and Development Co., Ltd. Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (tki)
WO2016038617A1 (en) 2014-09-11 2016-03-17 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Methods of producing mogrosides and compositions comprising same and uses thereof
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev NMDA receptor antagonists for the treatment of Gaucher disease
CN106999608A (zh) 2014-09-21 2017-08-01 耶路撒冷希伯来大学伊森姆研究发展公司 为了治疗脂质相关病症而下调mir‑132
JP6767374B2 (ja) 2014-10-20 2020-10-14 ジェン−プローブ・インコーポレーテッド 赤血球溶解溶液
EP3217785B1 (en) 2014-11-13 2023-10-25 Enzootic Holdings Ltd. Functional sex-reversal of decapod crustacean females
WO2016079736A2 (en) 2014-11-17 2016-05-26 Yeda Research And Development Co. Ltd. Methods of treating diseases related to mitochondrial function
CN107429291A (zh) 2014-11-17 2017-12-01 耶达研究及发展有限公司 分析微生物组的方法
CN107810271B (zh) 2014-11-20 2021-09-28 耶路撒冷希伯来大学伊萨姆研发公司 用于在植物细胞中生产具有改变的糖基化模式的多肽的组合物和方法
CN107208070B (zh) 2014-11-26 2021-09-07 技术创新动力基金（以色列）有限合伙公司 细菌基因的靶向消除
WO2016084084A1 (en) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Nucleic acid constructs for genome editing
US10688330B2 (en) 2014-12-11 2020-06-23 Yeda Research And Development Co. Ltd. Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
CN107209184B (zh) 2014-12-11 2020-04-24 米密德诊断学有限公司 用于诊断多种感染的标记组合及其使用方法
WO2016103269A1 (en) 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations of neural progenitor cells and methods of producing and using same
WO2016108240A1 (en) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Assessing retinal pigment epithelial cell populations
EA201791416A1 (ru) 2014-12-30 2017-11-30 Селл Кьюр Нейросайансес Лтд. Популяции клеток rpe и способы их получения
EP3240612B1 (en) 2014-12-30 2020-12-23 Cell Cure Neurosciences Ltd. Methods of treating retinal diseases
BR112017014433A2 (pt) 2015-01-04 2018-05-15 Protalix Ltd. proteína dnase i modificada, processo para preparar proteína dnase i modificada e composição farmacêutica
WO2016116935A1 (en) 2015-01-21 2016-07-28 Yeda Research And Development Co. Ltd. Use of rasa2 as a prognostic and therapeutic marker for melanoma
EP3256589B1 (en) 2015-01-22 2021-12-22 Monsanto Technology LLC Compositions and methods for controlling leptinotarsa
EP3261612A1 (en) 2015-02-26 2018-01-03 Yeda Research and Development Co. Ltd Method of promoting hair growth
WO2016142948A1 (en) 2015-03-11 2016-09-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Decoy oligonucleotides for the treatment of diseases
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
EP3273971A4 (en) 2015-03-27 2018-12-05 Yeda Research and Development Co. Ltd. Methods of treating motor neuron diseases
CA2981142A1 (en) 2015-03-27 2016-10-06 University Of Southern California Car t-cell therapy directed to lhr for the treatment of solid tumors
JP2018511325A (ja) 2015-03-31 2018-04-26 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． グルタミン酸オキサロ酢酸トランスアミナーゼ１（ｇｏｔ１）、その調製物および製造方法およびその使用
US10960035B2 (en) 2015-04-01 2021-03-30 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Voleaui Center) Erodium crassifolium L'Her plant extracts and uses thereof
CN107690429B (zh) 2015-04-07 2022-02-25 Ela制药有限公司 用于治疗和/或预防细胞或组织坏死的组合物，其特异性靶向组织蛋白酶c和/或cela1和/或cela3a和/或与其结构相关的酶
EP3081575A1 (en) 2015-04-12 2016-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anti-plasmodium parasite antibodies
US12023348B2 (en) 2015-04-27 2024-07-02 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions
US10674732B2 (en) 2015-04-29 2020-06-09 The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization Anti-phytopathogenic compositions
US20190031759A1 (en) 2015-04-30 2019-01-31 Technion Research & Development Foundation Limited Chimeric antigen receptors and methods of their use
EP3292219B9 (en) 2015-05-04 2022-05-18 Ramot at Tel-Aviv University Ltd. Methods and kits for fragmenting dna
WO2016181393A1 (en) 2015-05-11 2016-11-17 Yeda Research And Development Co. Ltd. Citrin inhibitors for the treatment of cancer
WO2016185471A1 (en) 2015-05-17 2016-11-24 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Compositions and methods for treating cancer
WO2016185457A1 (en) 2015-05-19 2016-11-24 Yeda Research And Development Co. Ltd. Methods of promoting lymphangiogenesis
WO2016185481A2 (en) 2015-05-20 2016-11-24 Yeda Research And Development Co. Ltd. Method of targeting senescent cells
EP3297727A1 (en) 2015-05-21 2018-03-28 Yeda Research and Development Co. Ltd Bacterial populations for promoting health
WO2016193969A2 (en) 2015-05-29 2016-12-08 Opko Biologics Ltd. Pegylated oxyntomodulin variants
WO2016196738A1 (en) 2015-06-02 2016-12-08 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
EP3302030A4 (en) 2015-06-03 2019-04-24 Monsanto Technology LLC METHOD AND COMPOSITIONS FOR INTRODUCING NUCLEIC ACIDS IN PLANTS
CN107847601A (zh) 2015-06-04 2018-03-27 南加利福尼亚大学 Lym‑1和lym‑2靶向的car细胞免疫疗法
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
ES2917884T3 (es) 2015-06-18 2022-07-12 Yeda Res & Dev Protocolos de acondicionamiento y uso de los mismos para la regeneración de tejidos
WO2016203476A1 (en) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and compositions for diagnosing and treating urothelial cancer
JP7096668B2 (ja) 2015-06-19 2022-07-06 オプコ バイオロジクス リミテッド 長時間作用型凝固因子およびその製造方法
EP3744340A3 (en) 2015-07-16 2021-03-03 Biokine Therapeutics Ltd. Compositions and methods for treating cancer
PL3322425T3 (pl) 2015-07-16 2023-10-09 Yeda Research And Development Co., Ltd. Zmodyfikowane genetycznie, skierowane przeciwko osobie trzeciej centralne limfocyty T pamięci i ich zastosowanie w immunoterapii
US10668094B2 (en) 2015-07-19 2020-06-02 Yeda Research And Development Co. Ltd. Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure
KR102460440B1 (ko) 2015-07-22 2022-10-28 피토파마 인터내셔널 리미티드 꿀벌―섭취가능한 조성물, 이를 이용한 꿀 생산 방법 및 이에 의해 생산된 꿀
US11230696B2 (en) 2015-07-29 2022-01-25 Hadasit Medical Research Services And Development Ltd. Large scale production of retinal pigment epithelial cells
ES2965461T3 (es) 2015-08-03 2024-04-15 Biokine Therapeutics Ltd Inhibidor de CXCR4 para el tratamiento del cáncer
US20180237774A1 (en) 2015-08-04 2018-08-23 Yeda Research And Development Co. Ltd. Methods of screening for riboswitches and attenuators
EA201890424A1 (ru) 2015-08-05 2018-06-29 Селл Кьюр Нейросайансес Лтд. Получение клеток пигментного эпителия сетчатки
WO2017021972A1 (en) 2015-08-05 2017-02-09 Cell Cure Neurosciences Ltd. Preparation of photoreceptors for the treatment of retinal diseases
WO2017025963A1 (en) 2015-08-10 2017-02-16 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and pharmaceutical compositions for improving wound healing using cd24
US20180237790A1 (en) 2015-08-13 2018-08-23 Forrest Innovation Ltd. Formulations and compositions for delivery of nucleic acids to plant cells
WO2017033188A1 (en) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Algal oil and biofuel and methods of producing same
US10765706B2 (en) 2015-09-03 2020-09-08 University Of South Florida Method of stem cell delivery into the brain during chronic disease using blood brain barrier permeabilizers
WO2017042816A1 (en) 2015-09-10 2017-03-16 Yeda Research And Development Co. Ltd. Ablation of perforin positive dendritic cells in cancer treatment
WO2017072757A1 (en) 2015-10-25 2017-05-04 Yeda Research And Development Co. Ltd. Antibodies targeting quiescin sulfhydryl oxidase (qsox1) and uses of same
CA3002919A1 (en) 2015-10-26 2017-05-04 Cell Cure Neurosciences Ltd. Preparation of retinal pigment epithelium cells
EP3368024B1 (en) 2015-10-27 2023-09-20 Akos Biosciences, Inc. Compositions comprising cannabidiol and second therapeutic agents for the treatment of cancer
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method for inducing the division of cardiomyocytes and treating heart diseases
WO2017077539A1 (en) 2015-11-03 2017-05-11 Ariel-University Research And Development Company Ltd. Compositions for regeneration and repair of neural tissue
WO2017081689A1 (en) 2015-11-11 2017-05-18 Ramot At Tel-Aviv University Ltd. Methods of detecting 5-hydroxymethylcytosine and diagnosing of cancer
US11679133B2 (en) 2015-11-30 2023-06-20 Kadimastem Ltd. Methods for differentiating and purifying pancreatic endocrine cells
EP3176183A1 (en) 2015-12-02 2017-06-07 Yeda Research and Development Co. Ltd Compositions and methods for treating cancer not resistant to a tyrosine kinase inhibitor (tki)
EP3389678B1 (en) 2015-12-16 2022-06-15 Ramot at Tel-Aviv University Ltd. Particles comprising decellularized omentum
WO2017115367A1 (en) 2015-12-28 2017-07-06 The National Institute for Biotechnology in the Negev Ltd. Composition and method for treating amyotrophic lateral sclerosis
CN108697907A (zh) 2016-01-06 2018-10-23 耶达研究及发展有限公司 用于治疗恶性疾病、自身免疫疾病和炎性疾病的组合物和方法
WO2017122203A1 (en) 2016-01-11 2017-07-20 Technion Research & Development Foundation Limited Methods of determining prognosis of sepsis and treating same
JP7019580B2 (ja) 2016-01-21 2022-02-15 ザ ステイト オブ イスラエル ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント アグリカルチュラル リサーチ オーガニゼイション （エー．アール．オー．） （ボルカニ センター） 単為結実植物およびその製造方法
IL243839B (en) 2016-01-28 2018-01-31 Sp Nano Ltd Conductive wires
IL243838A (en) 2016-01-28 2017-07-31 Sp Nano Ltd The composition containing sp1 protein and carbon nanoparticles and its uses
WO2017130205A1 (en) 2016-01-31 2017-08-03 Hadasit Medical Research Services And Development Ltd. Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
WO2017134671A1 (en) 2016-02-04 2017-08-10 Yeda Research And Development Co. Ltd. Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53
EP3414346B1 (en) 2016-02-14 2019-11-13 Yeda Research and Development Co. Ltd. Microbiome-based diagnosis, prediction and treatment of relapsing obesity
WO2017138008A2 (en) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Methods of modulating protein exocytosis and uses of same in therapy
AU2017220830A1 (en) 2016-02-16 2018-09-06 Yeda Research And Development Co. Ltd. Non-protein phenylalanine analogues for inhibiting cyanobacteria and plant growth
WO2017143156A1 (en) 2016-02-19 2017-08-24 Genisphere Llc Nucleic acid carriers and therapeutic methods of use
JP2019511919A (ja) 2016-02-23 2019-05-09 ブローディ，チャヤ がん幹細胞の作製およびその使用
IL261200B2 (en) 2016-03-01 2023-03-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Antibodies specific for the human poliovirus receptor
WO2017149547A1 (en) 2016-03-03 2017-09-08 Memed Diagnostics Ltd. Analyzing rna for diagnosing infection type
WO2017153982A1 (en) 2016-03-06 2017-09-14 Yeda Research And Development Co. Ltd. Method for modulating myelination
IL244649A0 (en) 2016-03-17 2016-06-30 Yeda Res & Dev Methods for the isolation of barrel-like proteases and the identification of peptides that are cleaved by Alidan
EP3440461A4 (en) 2016-04-06 2019-11-06 Technion Research & Development Foundation Limited INFILTRATING IMMUNEAN PARTS FOR PREDICTING AN ANTI-TNF ANSWER IN THICK DARM BIOPSIA
US10421785B2 (en) 2016-04-11 2019-09-24 Bar-Ilan University Delta receptor agonist peptides and use thereof
DE202017007130U1 (de) 2016-04-27 2019-08-29 Gen-Probe Inc. Lysereagenz für Blutzellen
EP3463402B1 (en) 2016-05-22 2021-06-23 Yeda Research and Development Co. Ltd. Methods of using pulmonary cells for transplantation and induction of tolerance
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of substances to treat drug-resistant tumors
WO2017208247A1 (en) 2016-06-02 2017-12-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Assay for the removal of methyl-cytosine residues from dna
WO2017212476A1 (en) 2016-06-05 2017-12-14 Tel Hashomer Medical Research Infrastructure And Services Ltd. Novel molecules for the treatment of inflammation
US20190160152A1 (en) 2016-06-09 2019-05-30 Opko Biologics Ltd. Long-acting oxyntomodulin formulation and methods of producing and administering same
CN109689894A (zh) 2016-06-19 2019-04-26 耶路撒冷希伯来大学伊萨姆研发有限公司 在人单倍体细胞中筛选化学疗法抗性
MX2019000022A (es) 2016-06-27 2019-09-18 Yeda Res & Dev Células veto generadas a partir de linfocitos t de memoria.
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
EP3482201B1 (en) 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
HUE064463T2 (hu) 2016-07-11 2024-03-28 Opko Biologics Ltd Hosszantartó hatású VII. koagulációs faktor és az elõállítására vonatkozó eljárások
IL291373B2 (en) 2016-07-11 2023-10-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
IL246722A0 (en) 2016-07-11 2016-09-29 Yeda Res & Dev Combination therapy to increase endogenous nitric oxide (no) synthesis
IL264205B2 (en) 2016-07-11 2023-12-01 Bonus Therapeutics Ltd Cellular compounds for tissue regeneration
ES3034904T3 (en) 2016-07-18 2025-08-27 Univ Ramot Modular platform for targeted therapeutics
US20190203270A1 (en) 2016-07-24 2019-07-04 Yeda Research And Development Co., Ltd. Methods and kits for analyzing dna binding moieties attached to dna
US10982252B2 (en) 2016-08-08 2021-04-20 Technology Innovation Momentum Fund (Israel) Limited Partnership Bacterial systems for analyzing ubiquitylated polypeptides
WO2018029693A1 (en) 2016-08-10 2018-02-15 Ramot At Tel-Aviv University Ltd. Analysis of methylation status and copy number
US12205677B2 (en) 2016-08-10 2025-01-21 Memed Diagnostics Ltd. System and method for analysis of biological data
PL3496730T3 (pl) 2016-08-14 2022-09-26 Ramot At Tel-Aviv University Ltd. Egzosomy pochodzące z komórek mezenchymalnych do leczenia zaburzeń neurologicznych
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
WO2018037416A1 (en) 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Methods and compositions for treating autoimmune diseases
PE20190839A1 (es) 2016-08-28 2019-06-17 The State Of Israel Ministry Of Agriculture And Rural Development Agricultural Res Organization Aro Metodo para controlar infecciones fungicas en plantas
JP2020501506A (ja) 2016-09-07 2020-01-23 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー． 抗ＮＫｐ４６抗体およびその治療的使用
US11485971B2 (en) 2016-09-14 2022-11-01 Yeda Research And Development Co. Ltd. CRISP-seq, an integrated method for massively parallel single cell RNA-seq and CRISPR pooled screens
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
IL248468A0 (en) 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
IL248385A0 (en) 2016-10-18 2017-02-01 Yeda Res & Dev Treatment of circadian rhythm disorder
WO2018087759A1 (en) 2016-11-10 2018-05-17 Yeda Research And Development Co. Ltd. Phosphotriesterases for treating or preventing organophosphate exposure associated damage
CN110234765A (zh) 2016-11-28 2019-09-13 耶达研究及发展有限公司 分离的多核苷酸和多肽及使用它们来表达感兴趣的表达产物的方法
US20190343782A1 (en) 2016-11-30 2019-11-14 Yeda Research And Development Co. Ltd. Methods of treating liver toxicity and disorders
SG11201810936VA (en) 2016-12-01 2019-01-30 Univ Ramot Combined treatment for nerve injuries
WO2018134824A1 (en) 2017-01-18 2018-07-26 Yeda Research And Development Co. Ltd. Genetically modified veto cells and use of same in immunotherapy
CN116908476A (zh) 2017-01-25 2023-10-20 St创新诊断有限公司 诊断恶性疾病的方法
IL250479A0 (en) 2017-02-06 2017-03-30 Sorek Rotem Genetically engineered cells expressing a disarm system that confers resistance to phages and methods for their production
US12281328B2 (en) 2017-02-08 2025-04-22 Hadasit Medical Research Services And Development Ltd. Photoreceptor cells for the treatment of retinal diseases
IL250916A0 (en) 2017-03-02 2017-06-29 Geiger Benjamin Methods for growing t cells in culture and their use
EP3596469A1 (en) 2017-03-12 2020-01-22 Yeda Research and Development Co., Ltd. Methods of diagnosing and prognosing cancer
WO2018167780A1 (en) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Methods of prognosing and treating cancer
CA3056653A1 (en) 2017-03-16 2018-09-20 Bio Time, Inc. Methods for the treatment of retinal diseases
WO2018185760A1 (en) 2017-04-05 2018-10-11 Yeda Research And Development Co. Ltd. Ex-vivo culture system and methods of using same
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Treatment of stress disorders
JP7445429B2 (ja) 2017-05-10 2024-03-07 アリエル サイエンティフィック イノベーションズ リミテッド 抗体の精製法
WO2018216006A1 (en) 2017-05-21 2018-11-29 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Combination of markers for diagnosing cancer
EP3634991A1 (en) 2017-05-23 2020-04-15 Technion Research & Development Foundation Limited Agents which inhibit gads dimerization and methods of use thereof
GB201708665D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing extractability of solids from coffee beans
GB201708662D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing shelf-life of banana
WO2018220582A1 (en) 2017-05-31 2018-12-06 Tropic Biosciences UK Limited Methods of selecting cells comprising genome editing events
WO2018229764A1 (en) 2017-06-13 2018-12-20 Yeda Research And Development Co. Ltd. Treatment of advanced or progressive multiple sclerosis
WO2019012544A1 (en) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. STRATEGY FOR DOUBLE PROBE DROPLETS FOR SPECIFIC DETECTION OF CIRCULATING DNA MOLECULES SPECIFIC TO A TISSUE
US20200165671A1 (en) 2017-07-13 2020-05-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Detecting tissue-specific dna
EP3652344A1 (en) 2017-07-13 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Dna targets as tissue-specific methylation markers
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combined treatment for cancer
IL253984A0 (en) 2017-08-14 2017-09-28 Yeda Res & Dev Immunotherapy against aranviruses that bind through transferrin receptor 1 (tfr1
JP7356412B2 (ja) 2017-08-21 2023-10-04 サヴィセル ダイアグノスティック リミテッド 肺癌を検出する方法
WO2019038771A1 (en) 2017-08-23 2019-02-28 Technion Research & Development Foundation Limited COMPOSITIONS AND METHODS FOR ENHANCING ALCOHOL TOLERANCE IN YEAST
WO2019058376A1 (en) 2017-09-19 2019-03-28 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) BIRDS WITH GENOME EDITION
BR112020005416A2 (pt) 2017-09-19 2020-09-29 Tropic Biosciences UK Limited modificação da especificidade de moléculas de rna não codificante para silenciar expressão gênica em células eucarióticas
EP4461356A3 (en) 2017-10-24 2025-01-22 Elani, Dalia Methods of treating an ischemic disease
AU2018364630A1 (en) 2017-11-09 2020-05-21 Pinteon Therapeutics Inc. Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with enhanced properties
US20200390800A1 (en) 2017-11-29 2020-12-17 Ramot At Tel-Aviv University Ltd. Methods of preventing or treating neurogenic shock
IL274978B2 (en) 2017-11-29 2024-10-01 Weedout Ltd Compositions, kits and methods for controlling weed of the amaranthus genus
EP3716993A1 (en) 2017-12-03 2020-10-07 Yeda Research and Development Co. Ltd Treatment of an ischemic heart disease
EP3723785A1 (en) 2017-12-17 2020-10-21 Yeda Research and Development Co. Ltd Cop9 signalosome (csn) complex modulators and uses thereof
EP3731965A1 (en) 2017-12-28 2020-11-04 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method to reproduce circadian rhythms on a microfluidic chip
IL257225A (en) 2018-01-29 2018-04-09 Yeda Res & Dev Treatment of sarcoma
EP4610372A2 (en) 2018-01-29 2025-09-03 Lavie Bio Ltd. Plant microbial preparations, compositions and formulations comprising same and uses thereof
IL257269A (en) 2018-01-31 2018-04-09 Olender Tsviya Signaling is directed to the endoplasmic reticulum
EP3749368A1 (en) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Methods of identifying and using agents for treating diseases associated with intestinal barrier dysfunction
WO2019155459A1 (en) 2018-02-08 2019-08-15 Yeda Research And Development Co. Ltd. Inhibitors of the 20s proteasome
WO2019162945A1 (en) 2018-02-23 2019-08-29 Carmel Haifa University Economic Corporation Ltd. Methods for treating memory impairment and cognitive dysfunction
WO2019167047A1 (en) 2018-02-28 2019-09-06 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
EP3765034A1 (en) 2018-03-12 2021-01-20 Yeda Research and Development Co. Ltd Treatment of a heart disease
EP3774047A1 (en) 2018-03-29 2021-02-17 Yeda Research and Development Co. Ltd Use of electric field gradients to control gene expression
IL258467A (en) 2018-03-29 2018-07-04 Ilana Kolodkin Gal Methods of disrupting a biofilm and/or preventing formation of same
IL314908A (en) 2018-03-29 2024-10-01 Technion Res & Dev Foundation Vesicles comprising a pten inhibitor and uses of same
GB201807192D0 (en) 2018-05-01 2018-06-13 Tropic Biosciences Uk Ltd Compositions and methods for reducing caffeine content in coffee beans
IL259392A (en) 2018-05-15 2018-08-01 Yeda Res & Dev Vaccination with cancer neoantigens
WO2019220441A1 (en) 2018-05-15 2019-11-21 Hadasit Medical Research Services And Development Ltd. Compositions and methods for treating cancer resistant to an anti-cancer agent
US20210121491A1 (en) 2018-05-27 2021-04-29 Biolinerx Ltd. Agi-134 combined with a checkpoint inhibitor for the treatment of solid tumors
US11827892B2 (en) 2018-06-07 2023-11-28 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Nucleic acid constructs and methods of using same
CA3102975A1 (en) 2018-06-07 2019-12-12 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Methods of regenerating and transforming cannabis
WO2020003311A1 (en) 2018-06-25 2020-01-02 Yeda Research And Development Co. Ltd. Systems and methods for increasing efficiency of genome editing
EP3818075A1 (en) 2018-07-04 2021-05-12 Ukko Inc. Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease
WO2020012467A2 (en) 2018-07-08 2020-01-16 Yeda Research And Development Co. Ltd. Person-specific assessment of probiotics responsiveness
BR112021000360A2 (pt) 2018-07-11 2021-04-13 Kahr Medical Ltd. Proteína de fusão variante sirpalpha-4-1bbl e métodos de uso da mesma
HRP20250746T1 (hr) 2018-07-11 2025-08-15 Immunity Pharma Ltd. Peptidni spojevi i njihova terapijska upotreba
US20210310082A1 (en) 2018-07-31 2021-10-07 Collplant Ltd. Tobacco transgenic event and methods for detection and use thereof
IL261156A (en) 2018-08-14 2020-02-27 Fass Deborah Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
WO2020039440A1 (en) 2018-08-24 2020-02-27 Yeda Research And Development Co. Ltd. Methods of modulating m2 macrophage polarization and use of same in therapy
US20210353611A1 (en) 2018-09-20 2021-11-18 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral sclerosis
WO2020065647A1 (en) 2018-09-25 2020-04-02 Biolinerx Ltd. Methods of selecting treatment for cxcr4-associated cancer
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
IL263184A (en) 2018-11-21 2020-05-31 Yarden Yosef Method of treating cancer and compositions for same
EP3914698B1 (en) 2019-01-23 2024-12-11 Yeda Research and Development Co. Ltd Culture media for pluripotent stem cells
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
IL264854A (en) 2019-02-14 2020-08-31 Bahat Anat Spt5 inhibitors and methods of use thereof
WO2020170240A1 (en) 2019-02-21 2020-08-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reduction drug-induced nephrotoxicity
EP3927807A1 (en) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Methods of generating organoids for high throughput screening of drugs
MX2021010611A (es) 2019-03-05 2021-11-12 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Aves con genoma editado.
WO2020185763A1 (en) 2019-03-11 2020-09-17 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
IL265486A (en) 2019-03-19 2020-09-30 Yeda Res & Dev Bistable type ii opsins and uses thereof
WO2020194317A1 (en) 2019-03-28 2020-10-01 Yeda Research And Development Co. Ltd. Method of treating lipid-related disorders
US12419902B2 (en) 2019-03-31 2025-09-23 Yeda Research And Development Co. Ltd. Anti-viral and anti-tumoral compounds
IL266433B (en) 2019-05-02 2020-11-30 Sagi Irit Preparations containing the propeptide of lysyl oxidase and their uses
WO2020230133A1 (en) 2019-05-13 2020-11-19 Yeda Research And Development Co. Ltd. Cell-free mirna biomarkers for prognosis and diagnosis of neurodegenerative diseases
IL266728B (en) 2019-05-19 2020-11-30 Yeda Res & Dev Identification of recurrent mutant neopeptides
EP3973049A1 (en) 2019-05-22 2022-03-30 Hadasit Medical Research Services and Development Ltd. Methods of culturing human pluripotent cells
EP3976646A4 (en) 2019-05-28 2023-04-19 Shanghaitech University COMPOSITION AND METHODS FOR THE TREATMENT OF ECTODERMAL DYSPLASIA 2, CLOUSTON TYPE
EP3983531A1 (en) 2019-06-12 2022-04-20 Hadasit Medical Research Services and Development Ltd. Methods of generating oligodendrocytes
US20220307008A1 (en) 2019-06-16 2022-09-29 Yeda Research And Development Co. Ltd. Method for stabilizing intracellular rna
US20220251193A1 (en) 2019-06-27 2022-08-11 Ramot At Tel-Aviv University Ltd. Semaphorin 3a antibodies and uses thereof
JP2022538647A (ja) 2019-07-04 2022-09-05 ウッコ インコーポレイテッド 脱エピトープ化されたアルファグリアジン、ならびにセリアック病およびグルテン過敏症の管理のためのその使用
CN114375310A (zh) 2019-07-11 2022-04-19 卡尔医学有限公司 数个异二聚体及其数个使用方法
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
WO2021009740A1 (en) 2019-07-16 2021-01-21 Ramot At Tel-Aviv University Ltd. Compositions and methods for the treatment of tuberculosis
EP4004548A1 (en) 2019-07-29 2022-06-01 Yeda Research and Development Co. Ltd Methods of treating and diagnosing lung cancer
EP4004212A1 (en) 2019-07-30 2022-06-01 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute) Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
WO2021028909A1 (en) 2019-08-12 2021-02-18 Yeda Research And Development Co. Ltd. Dna repair blood test for predicting response of lung cancer patients to immunotherapy
WO2021033176A1 (en) 2019-08-22 2021-02-25 Ariel Scientific Innovations Ltd. Scaled-up methods for purifying antibodies
WO2021038569A1 (en) 2019-08-27 2021-03-04 Yeda Research And Development Co. Ltd. Treatment of bacterial vaginosis
WO2021048852A1 (en) 2019-09-11 2021-03-18 Yeda Research And Development Co. Ltd. Methods of treating breast cancer
IL269674B (en) 2019-09-25 2020-08-31 Roy Bar Ziv Assembling protein complexes on a chip
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
EP4051695A1 (en) 2019-10-31 2022-09-07 Yeda Research and Development Co., Ltd. Engineered autotrophic bacteria for co2 conversion to organic materials
AU2020384953A1 (en) 2019-11-11 2022-06-23 Ibi-Ag Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
IL293148A (en) 2019-11-19 2024-07-01 Protalix Ltd Removal of constructs from transduced cells
IL270800A (en) 2019-11-20 2021-05-31 Yeda Res & Dev A method for treating Alzheimer's disease
EP4077731A1 (en) 2019-12-22 2022-10-26 Yeda Research and Development Co. Ltd Diagnosis of frontotemporal dementia
IL271656A (en) 2019-12-22 2021-06-30 Yeda Res & Dev System and methods for identifying cells that have undergone genome editing
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods for treating atopic dermatitis
WO2021137231A1 (en) 2019-12-31 2021-07-08 Kahr Medical Ltd. Methods of culturing t cells with a 4-1bbl fusion polypeptide and uses of same
US20230048361A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells and uses of same
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same
IL272194A (en) 2020-01-22 2021-07-29 Yeda Res & Dev Multi-target antibodies for use in the treatment of diseases
WO2021152584A1 (en) 2020-01-28 2021-08-05 Ariel Scientific Innovations Ltd. Methods of analyzing cell membranes
EP4484956A3 (en) 2020-01-29 2025-07-16 MeMed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
IL272389A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Kits containing antibodies to PD-L1 and their uses in therapy
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Cancer treatment methods
WO2021152586A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
WO2021152587A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Treating acute liver disease with tlr-mik inhibitors
IL295500A (en) 2020-02-09 2022-10-01 Nlc Pharma Ltd Rapid detection test for sars-cov-2
IL272586A (en) 2020-02-10 2021-08-31 Yeda Res & Dev A method for cell cluster analysis
WO2021173674A1 (en) 2020-02-26 2021-09-02 A2 Biotherapeutics, Inc. Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
US20230127559A1 (en) 2020-03-16 2023-04-27 Yeda Research And Development Co. Ltd. Peptide analogs and use of same in treating diseases, disorders or conditions associated with mutant p53 protein
BR112022019510A2 (pt) 2020-03-29 2022-11-16 Yeda Res & Dev Variantes de beta-glucocerebrosidase para uso no tratamento de doença de gaucher
WO2021199047A1 (en) 2020-03-31 2021-10-07 Biomuse Ltd. Bacteria for the prevention and treatment of smoke-induced lung damage
EP4133107A1 (en) 2020-04-06 2023-02-15 Yeda Research and Development Co. Ltd Methods of diagnosing cancer and predicting responsiveness to therapy
WO2021205459A1 (en) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Cannabidiol-containing compositions and uses thereof
EP4135746A1 (en) 2020-04-13 2023-02-22 Exoprother Medical Ltd. Cell-derived vesicles comprising wild-type p53 protein for antiviral therapy
US20210322483A1 (en) 2020-04-16 2021-10-21 Ichilov Tech Ltd. Cell-derived particles presenting heterologous cd24 and use thereof in therapy
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
IL274811B (en) 2020-05-20 2021-05-31 Yeda Res & Dev Spatial information is developed for the analysis of individual cells
US20230220459A1 (en) 2020-06-10 2023-07-13 Ramot At Tel-Aviv University Ltd. METHODS OF DETECTING METHYLATED CpG
WO2021260696A1 (en) 2020-06-22 2021-12-30 Ramot At Tel-Aviv University Ltd. Multi subunit protein modules, cells expressing same and uses thereof
WO2021260675A1 (en) 2020-06-24 2021-12-30 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
IL276599A (en) 2020-08-09 2022-03-01 Yeda Res & Dev T cell receptor unique to mage-a1 and its uses
IL276627A (en) 2020-08-10 2022-03-01 Yeda Res & Dev Compositions for diagnosis and treatment of coronavirus infections
EP4199703A1 (en) 2020-08-18 2023-06-28 International Rice Research Institute Methods of increasing outcrossing rates in gramineae
IL277488A (en) 2020-09-21 2022-04-01 Yeda Res & Dev Weight regulation method
WO2022064494A2 (en) 2020-09-23 2022-03-31 Yeda Research And Development Co. Ltd. Methods and compositions for treating coronaviral infections
IL277743A (en) 2020-10-01 2022-04-01 Yeda Res & Dev A method for diagnosing breast cancer
JP2023545999A (ja) 2020-10-05 2023-11-01 プロタリクス リミテッド ダイサー（ｄｉｃｅｒ）様ノックアウト植物細胞
JP2023545740A (ja) 2020-10-07 2023-10-31 プロタリクス リミテッド 長期活性ＤＮａｓｅ
WO2022079719A1 (en) 2020-10-15 2022-04-21 Yeda Research And Development Co. Ltd. Method of treating myeloid malignancies
IL278401A (en) 2020-10-29 2022-05-01 Yeda Res & Dev Polynucleotides for editing RNA and a method for using them
US20230416750A1 (en) 2020-11-09 2023-12-28 1E Therapeutics Ltd. Catalytic sequence based methods of treating or preventing bacterial infections
EP4251641A1 (en) 2020-11-26 2023-10-04 Ukko Inc. Modified high molecular weight glutenin subunit and uses thereof
IL279559A (en) 2020-12-17 2022-07-01 Yeda Res & Dev Controlling ubiquitination of mlkl for treatment of disease
WO2022144883A2 (en) 2020-12-28 2022-07-07 1E Therapeutics, Ltd. P21 mrna targeting dnazymes
AU2021411103B2 (en) 2020-12-28 2025-04-24 1E Therapeutics, Ltd. P21 mrna target areas for silencing
AU2022206415A1 (en) 2021-01-10 2023-08-17 Supermeat The Essence Of Meat Ltd. Pluripotent stem cell aggregates and microtissues obtained therefrom for the cultured meat industry
WO2022153286A1 (en) 2021-01-14 2022-07-21 Yeda Research And Development Co. Ltd. Methods of producing vitamin d
IL280340B (en) 2021-01-21 2022-04-01 Yeda Res & Dev Antibodies, peptides and their combinations for the treatment and prevention of corona virus infections
JP2024506954A (ja) 2021-02-18 2024-02-15 イェダ リサーチ アンド デベロップメント カンパニー リミテッド ワクチン作製用の遺伝子改変細菌
EP4294428A1 (en) 2021-02-18 2023-12-27 Yeda Research and Development Co. Ltd Method of generating vaccines
IL281561A (en) 2021-03-16 2022-10-01 Yeda Res & Dev Methods and devices for ex-utero mouse embryonic development
CA3213424A1 (en) 2021-03-30 2022-10-06 Lior Moshe ZELCBUCH Pseudomonas bacteriophage and uses thereof
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev Combined use of ketamine and bretigabine for the treatment of psychiatric disorders
US20240415904A1 (en) 2021-05-12 2024-12-19 Biomx Ltd. Staphylococcus bacteriophage and uses thereof
IL283563A (en) 2021-05-30 2022-12-01 Yeda Res & Dev Profiling of amps for the diagnosis, monitoring and treatment of microbiome-related diseases
IL309061A (en) 2021-06-06 2024-02-01 Yeda res & development co ltd Combined treatment for cancer
CN117836402A (zh) 2021-06-13 2024-04-05 耶路撒冷希伯来大学伊森姆研究发展有限公司 重编程人细胞的方法
NL2028466B1 (en) 2021-06-16 2022-12-21 Sakata Holland B V Methods of sorting matthiola seeds
JP2024530389A (ja) 2021-06-16 2024-08-21 シードエックス テクノロジーズ インク マッティオラ属種子を選別する方法
KR20240031315A (ko) 2021-07-02 2024-03-07 트로픽 바이오사이언시즈 유케이 리미티드 바나나 과실의 갈변 지연 또는 예방
CN117980470A (zh) 2021-07-18 2024-05-03 盖米达细胞有限公司 治疗性nk细胞群
WO2023002492A1 (en) 2021-07-22 2023-01-26 Yeda Research And Development Co. Ltd. Codon optimization of nucleic acids
EP4380973A2 (en) 2021-08-02 2024-06-12 Yeda Research and Development Co. Ltd. Anti-matrix metalloproteinase-14 antibodies for the treatment of cancer
EP4130028A1 (en) 2021-08-03 2023-02-08 Rhazes Therapeutics Ltd Engineered tcr complex and methods of using same
EP4380966A2 (en) 2021-08-03 2024-06-12 Genicity Limited Engineered tcr complex and methods of using same
CN118369418A (zh) 2021-08-10 2024-07-19 盖米达细胞有限公司 工程nk细胞、它们的生产方法及其用途
GB202112865D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to black sigatoka disease in banana
GB202112866D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to fusarium wilt in a banana
IL286430A (en) 2021-09-14 2023-04-01 Yeda Res & Dev Multispecific antibodies for use in the treatment of diseases
JP2024542847A (ja) 2021-12-08 2024-11-15 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 肺の再生のための多分化能性肺前駆細胞
EP4499108A1 (en) 2022-04-25 2025-02-05 Yeda Research and Development Co. Ltd Compositions for altering cyclic adp-ribose secondary messenger signalling
CN115385934A (zh) * 2022-10-26 2022-11-25 北京纳百生物科技有限公司 一种舒巴坦半抗原及其合成方法和应用
WO2025150045A1 (en) 2024-01-12 2025-07-17 Gabriel Nussbaum Bacterial targets, therapeutics, compositions, kits and methods of use in treating and/or preventing cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3709868A (en) * 1971-03-08 1973-01-09 Hoffmann La Roche Opium alkaloid antigens and antibodies specific therefor
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3766162A (en) * 1971-08-24 1973-10-16 Hoffmann La Roche Barbituric acid antigens and antibodies specific therefor

Also Published As

Publication number Publication date
FR2184371A5 (cs) 1973-12-21
DE2323467C2 (de) 1982-01-14
AT328612B (de) 1976-03-25
NL7206373A (cs) 1973-11-13
JPS5317648B2 (cs) 1978-06-09
NL171930B (nl) 1983-01-03
CA1011232A (en) 1977-05-31
BR7303420D0 (pt) 1974-08-29
FI52154C (fi) 1977-06-10
DK135965B (da) 1977-07-18
AU5517073A (en) 1974-11-07
HU169436B (cs) 1976-11-28
ES414618A1 (es) 1976-09-01
BE799417A (fr) 1973-11-12
FI52154B (cs) 1977-02-28
JPS4962192A (cs) 1974-06-17
DK135965C (cs) 1977-12-19
US3879262A (en) 1975-04-22
ZA732924B (en) 1974-04-24
DE2323467A1 (de) 1973-11-29
AR200129A1 (es) 1974-10-24
GB1433783A (en) 1976-04-28
ATA416473A (de) 1975-06-15
NL171930C (nl) 1983-06-01
SE417015B (sv) 1981-02-16

Similar Documents

Publication Publication Date Title
DE2323467C2 (de) Verfahren zum Nachweis und zur Bestimmung von Haptenen
DE2155658C3 (de) Verfahren zum Nachweis und zur Bestimmung von einem Hapten oder dessen Antikörper
DE3650513T2 (de) Verzögerter immunologischer Test in fester Phase
DE2743444C3 (de) Immunchemisches Meßverfahren und Reagens zu seiner Durchführung
EP1219964B1 (de) Nachweisverfahren, in welchem der High-Dose-Hook-Effekt vermieden, verringert oder nachgewiesen wird
EP0397113B1 (de) Verfahren zum Nachweis spezifisch bindefähiger Substanzen in Körperflüssigkeiten
DE2164768B2 (de) Verfahren zum nachweis und zur bestimmung einer komponente der reaktion zwischen spezifischen bindeproteinen und bindefaehigen substanzen
DE2206103A1 (de) Verfahren zum Nachweisen und Bestimmen einer Komponente der Reaktion zwischen spezifisch bindenden Proteinen und den Substanzen, die von diesen Proteinen spezifisch gebunden werden
CH645465A5 (de) Immunbiologisches verfahren zur quantitativen bestimmung von haptenen und testausruestung zur durchfuehrung des verfahrens.
EP0363942A2 (de) Verfahren zur Bestimmung einer spezifisch bindefähigen Substanz
DE69131811T2 (de) Antikörpern gegen Ligand-Analogen und ihre Verwendung in Ligand-Rezeptor Bestimmungen
EP0349988B1 (de) Verfahren zur Bestimmung einer spezifisch bindefähigen Substanz
DE3433652A1 (de) Immunchemisches messverfahren fuer haptene und proteine
EP0747699B1 (de) Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex
DE3224217A1 (de) Enzymimmunoassay-methode zur qualitativen und quantitativen bestimmung von substanzen
DE69428998T2 (de) Reagenzien und verfahren zur detektion und quantitativen bestimmung von testosteron in flüssigen proben
DE3877032T2 (de) Diagnostischer immunoassay fuer digoxin mit festphasetrennung.
DE2721267A1 (de) Polymermatrix auf der basis von acrylamid
DE69822446T2 (de) Cyclosporin derivate und deren verwendung
EP0289003B1 (de) Immunchemisches Verfahren und Reagenz zur Bestimmung eines polyvalenten Antigens in einer flüssigen Probe
WO2005062057A1 (de) Konjugate und deren verwendung in nachweisverfahren
DE3100061A1 (de) Verfahren zur bestimmung von liganden mittels kompetitionsreaktion
DE3781841T2 (de) Diagnostisches immuntest-verfahren mittels festphasenabscheidung.
DE3504406A1 (de) Verfahren zur bestimmung der bindungskapazitaet des thyroxin bindenden globulins
DE3587845T2 (de) Verfahren zur Bestimmung eines Liganden.

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased