PT1020454E - Modificações polimórficas do ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil-5-tiazole-carboxílico e processos para a sua preparação - Google Patents

Modificações polimórficas do ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil-5-tiazole-carboxílico e processos para a sua preparação Download PDF

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Publication number
PT1020454E
PT1020454E PT99957054T PT99957054T PT1020454E PT 1020454 E PT1020454 E PT 1020454E PT 99957054 T PT99957054 T PT 99957054T PT 99957054 T PT99957054 T PT 99957054T PT 1020454 E PT1020454 E PT 1020454E
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PT
Portugal
Prior art keywords
isobutyloxyphenyl
cyano
methyl
polymorphs
thiazole
Prior art date
Application number
PT99957054T
Other languages
English (en)
Inventor
Koichi Matsumoto
Kenzo Watanabe
Toshiyuki Hiramatsu
Mitsutaka Kitamura
Original Assignee
Teijin Pharma Ltd
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15953825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1020454(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Publication of PT1020454E publication Critical patent/PT1020454E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT99957054T 1998-06-19 1999-06-18 Modificações polimórficas do ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil-5-tiazole-carboxílico e processos para a sua preparação PT1020454E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17307998 1998-06-19

Publications (1)

Publication Number Publication Date
PT1020454E true PT1020454E (pt) 2009-12-21

Family

ID=15953825

Family Applications (3)

Application Number Title Priority Date Filing Date
PT80059330T PT1956014T (pt) 1998-06-19 1999-06-18 Polimorfos de ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil- 5-tiazolecarboxílico e método para a sua produção
PT99957054T PT1020454E (pt) 1998-06-19 1999-06-18 Modificações polimórficas do ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil-5-tiazole-carboxílico e processos para a sua preparação
PT08005934T PT1956015E (pt) 1998-06-19 1999-06-18 Polimorfo de ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil- 5-tiazole-carboxílico e método para a sua produção

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT80059330T PT1956014T (pt) 1998-06-19 1999-06-18 Polimorfos de ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil- 5-tiazolecarboxílico e método para a sua produção

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT08005934T PT1956015E (pt) 1998-06-19 1999-06-18 Polimorfo de ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil- 5-tiazole-carboxílico e método para a sua produção

Country Status (39)

Country Link
US (1) US6225474B1 (pt)
EP (4) EP2404910A3 (pt)
JP (1) JP3547707B2 (pt)
KR (1) KR100511183B1 (pt)
CN (3) CN1275126A (pt)
AT (2) ATE449765T1 (pt)
AU (1) AU748026B2 (pt)
BE (1) BE2010C024I2 (pt)
BG (1) BG64734B1 (pt)
BR (1) BR9906539A (pt)
CA (2) CA2566652C (pt)
CY (3) CY1109720T1 (pt)
CZ (1) CZ298170B6 (pt)
DE (2) DE69941672D1 (pt)
DK (3) DK1956015T4 (pt)
ES (3) ES2371786T5 (pt)
FR (1) FR10C0022I2 (pt)
GT (1) GT199900216A (pt)
HK (2) HK1029788A1 (pt)
HR (2) HRP20000092C1 (pt)
HU (2) HU229405B1 (pt)
ID (1) ID25775A (pt)
IL (1) IL134594A (pt)
IN (1) IN191537B (pt)
IS (4) IS9020A (pt)
LT (1) LT1956014T (pt)
LU (1) LU91682I2 (pt)
NO (1) NO321308B1 (pt)
NZ (1) NZ503326A (pt)
PL (1) PL200710B1 (pt)
PT (3) PT1956014T (pt)
RU (1) RU2198169C3 (pt)
SI (3) SI1020454T2 (pt)
SK (2) SK287946B6 (pt)
TR (1) TR200000458T1 (pt)
TW (1) TWI248439B (pt)
UA (1) UA57611C2 (pt)
WO (1) WO1999065885A1 (pt)
ZA (1) ZA200000737B (pt)

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GR1009119B (el) 2016-06-30 2017-09-18 "Φαρματεν Α.Β.Ε.Ε." Φαρμακευτικο σκευασμα περιεχον ενα μη πουρινικο επιλεκτικο αναστολεα της οξειδασης της ξανθινης και μεθοδος παρασκευης αυτου
KR20180013563A (ko) * 2016-07-29 2018-02-07 한미정밀화학주식회사 고순도 결정형 페북소스타트의 개선된 제조 방법
CN106565627B (zh) * 2016-10-10 2020-01-10 扬子江药业集团有限公司 一种非布司他药用晶型的制备方法
GR1009659B (el) 2018-09-07 2019-11-28 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα που περιλαμβανει ενα συμπλοκο αλατος της φεβουξοστατης με οξειδιο του μαγνησιου και μεθοδος για την παρασκευη αυτου
JP7389044B2 (ja) 2018-09-28 2023-11-29 株式会社カネカ 安定性に優れた還元型補酵素ｑ１０結晶の製造方法
CN112390766B (zh) * 2019-08-13 2022-09-06 浙江天宇药业股份有限公司 一种非布司他a晶型的制备方法
CN111004191A (zh) * 2019-10-24 2020-04-14 武汉光谷亚太医药研究院有限公司 一种大粒径非布司他a晶的制备方法
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BR9906539A (pt) 2000-08-15
IS5377A (is) 2000-02-17
EP1020454A1 (en) 2000-07-19
DK1020454T3 (da) 2010-01-04
DE122010000013I1 (de) 2010-07-08
IL134594A0 (en) 2001-04-30
EP2404910A3 (en) 2014-10-29
EP1020454B2 (en) 2013-01-23
PT1956015E (pt) 2011-11-02
UA57611C2 (uk) 2003-06-16
IS3002B (is) 2018-09-15
CA2566652C (en) 2008-10-21
ATE522512T2 (de) 2011-09-15
EP1020454B1 (en) 2009-11-25
ES2336287T5 (es) 2013-04-02
EP1956015A2 (en) 2008-08-13
EP1956014A3 (en) 2008-08-20
CY1109720T1 (el) 2012-01-25
WO1999065885A1 (en) 1999-12-23
HRP20120217B1 (hr) 2019-04-05
SK287946B6 (sk) 2012-06-04
IN191537B (pt) 2003-12-06
IL134594A (en) 2004-12-15
CA2301863A1 (en) 1999-12-23
ES2718467T3 (es) 2019-07-02
GT199900216A (es) 2001-06-08
ES2371786T3 (es) 2012-01-10
EP1956015A3 (en) 2008-09-17
TWI248439B (en) 2006-02-01
IS2886B (is) 2014-07-15
CZ2000582A3 (cs) 2000-07-12
AU4289299A (en) 2000-01-05
RU2198169C3 (ru) 2017-07-20
HRP20000092A2 (en) 2000-08-31
EP2404910A2 (en) 2012-01-11
KR20010023061A (ko) 2001-03-26
HK1118293A1 (pt) 2009-02-06
CY2010006I1 (el) 2012-01-25
ES2336287T3 (es) 2010-04-09
EP1956014A2 (en) 2008-08-13
SI1956015T1 (sl) 2011-10-28
AU748026B2 (en) 2002-05-30
BG64734B1 (bg) 2006-01-31
DE69941672D1 (de) 2010-01-07
SK2202000A3 (en) 2000-11-07
SI1956015T2 (sl) 2018-12-31
SK287928B6 (sk) 2012-04-03
HU229405B1 (en) 2013-12-30
CZ298170B6 (cs) 2007-07-11
DK1956015T4 (en) 2019-02-11
LT1956014T (lt) 2019-03-25
IS9020A (is) 2013-01-25
ZA200000737B (en) 2000-09-08
HRP20000092C1 (en) 2012-04-30
SI1956014T1 (sl) 2019-02-28
FR10C0022I2 (fr) 2013-08-16
DK1956014T3 (en) 2019-04-15
HRP20120217A2 (hr) 2012-05-31
EP1956015B1 (en) 2011-08-31
TR200000458T1 (tr) 2000-10-23
BE2010C024I2 (en) 2018-08-24
HUP0004325A3 (en) 2001-12-28
CA2566652A1 (en) 1999-12-23
PT1956014T (pt) 2019-04-24
BG104159A (en) 2000-08-31
PL200710B1 (pl) 2009-01-30
US6225474B1 (en) 2001-05-01
HK1029788A1 (en) 2001-04-12
CY2010006I2 (el) 2012-01-25
HRPK20000092B1 (en) 2001-10-31
NO20000789D0 (no) 2000-02-17
CN102020617A (zh) 2011-04-20
ID25775A (id) 2000-11-02
HU230799B1 (hu) 2018-06-28
FR10C0022I1 (pt) 2010-05-14
CN102659712A (zh) 2012-09-12
KR100511183B1 (ko) 2005-08-30
LU91682I9 (pt) 2019-01-09
LU91682I2 (fr) 2010-06-22
NZ503326A (en) 2002-02-01
RU2198169C2 (ru) 2003-02-10
ES2371786T5 (es) 2019-04-22
JP3547707B2 (ja) 2004-07-28
IS9021A (is) 2013-01-25
EP1956014B1 (en) 2019-01-16
EP1020454A4 (en) 2002-05-15
SI1020454T1 (sl) 2010-02-26
NO20000789L (no) 2000-02-17
PL338780A1 (en) 2000-11-20
CY1111841T1 (el) 2015-10-07
DK1956015T3 (da) 2011-09-26
DK1020454T4 (da) 2013-11-25
CN102020617B (zh) 2019-04-23
SI1020454T2 (sl) 2013-03-29
IS9022A (is) 2013-01-25
CN1275126A (zh) 2000-11-29
ATE449765T1 (de) 2009-12-15
NO321308B1 (no) 2006-04-24
HUP0004325A2 (hu) 2001-10-28
EP1956015B2 (en) 2018-11-14

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