BE2010C024I2 - Polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and method of producing the same - Google Patents
Polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and method of producing the sameInfo
- Publication number
- BE2010C024I2 BE2010C024I2 BE2010C024C BE2010C024C BE2010C024I2 BE 2010C024 I2 BE2010C024 I2 BE 2010C024I2 BE 2010C024 C BE2010C024 C BE 2010C024C BE 2010C024 C BE2010C024 C BE 2010C024C BE 2010C024 I2 BE2010C024 I2 BE 2010C024I2
- Authority
- BE
- Belgium
- Prior art keywords
- isobutyloxyphenyl
- cyano
- methyl
- producing
- thiazolecarboxylic acid
- Prior art date
Links
- BQSJTQLCZDPROO-UHFFFAOYSA-N febuxostat Chemical compound C1=C(C#N)C(OCC(C)C)=CC=C1C1=NC(C)=C(C(O)=O)S1 BQSJTQLCZDPROO-UHFFFAOYSA-N 0.000 title abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000012046 mixed solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17307998 | 1998-06-19 | ||
PCT/JP1999/003258 WO1999065885A1 (fr) | 1998-06-19 | 1999-06-18 | Modifications polymorphes de 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazole-acide carboxylique et procedes de preparation associes |
EP99957054A EP1020454B2 (fr) | 1998-06-19 | 1999-06-18 | Modifications polymorphes de 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazole-acide carboxylique et procedes de preparation associes |
Publications (1)
Publication Number | Publication Date |
---|---|
BE2010C024I2 true BE2010C024I2 (en) | 2018-08-24 |
Family
ID=15953825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE2010C024C BE2010C024I2 (en) | 1998-06-19 | 2010-05-12 | Polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and method of producing the same |
Country Status (39)
Country | Link |
---|---|
US (1) | US6225474B1 (fr) |
EP (4) | EP2404910A3 (fr) |
JP (1) | JP3547707B2 (fr) |
KR (1) | KR100511183B1 (fr) |
CN (3) | CN102659712A (fr) |
AT (2) | ATE449765T1 (fr) |
AU (1) | AU748026B2 (fr) |
BE (1) | BE2010C024I2 (fr) |
BG (1) | BG64734B1 (fr) |
BR (1) | BR9906539A (fr) |
CA (2) | CA2566652C (fr) |
CY (3) | CY1109720T1 (fr) |
CZ (1) | CZ298170B6 (fr) |
DE (2) | DE122010000013I1 (fr) |
DK (3) | DK1020454T4 (fr) |
ES (3) | ES2371786T5 (fr) |
FR (1) | FR10C0022I2 (fr) |
GT (1) | GT199900216A (fr) |
HK (2) | HK1029788A1 (fr) |
HR (2) | HRP20000092C1 (fr) |
HU (2) | HU229405B1 (fr) |
ID (1) | ID25775A (fr) |
IL (1) | IL134594A (fr) |
IN (1) | IN191537B (fr) |
IS (4) | IS9020A (fr) |
LT (1) | LT1956014T (fr) |
LU (1) | LU91682I2 (fr) |
NO (1) | NO321308B1 (fr) |
NZ (1) | NZ503326A (fr) |
PL (1) | PL200710B1 (fr) |
PT (3) | PT1956014T (fr) |
RU (1) | RU2198169C3 (fr) |
SI (3) | SI1956015T2 (fr) |
SK (2) | SK287946B6 (fr) |
TR (1) | TR200000458T1 (fr) |
TW (1) | TWI248439B (fr) |
UA (1) | UA57611C2 (fr) |
WO (1) | WO1999065885A1 (fr) |
ZA (1) | ZA200000737B (fr) |
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AU2003220909B2 (en) * | 2002-03-28 | 2008-09-18 | Teijin Limited | Solid preparation containing single crystal form |
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EP2881116A1 (fr) | 2013-12-05 | 2015-06-10 | Ranbaxy Laboratories Limited | Composition de febuxostat |
EP2902016A1 (fr) | 2014-01-30 | 2015-08-05 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Comprimé Febuxostat |
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1999
- 1999-06-18 HU HU0004325A patent/HU229405B1/hu active Protection Beyond IP Right Term
- 1999-06-18 SK SK5040-2010A patent/SK287946B6/sk not_active IP Right Cessation
- 1999-06-18 HU HU1300546A patent/HU230799B1/hu unknown
- 1999-06-18 CN CN2012101505038A patent/CN102659712A/zh active Pending
- 1999-06-18 TR TR2000/00458T patent/TR200000458T1/xx unknown
- 1999-06-18 IL IL13459499A patent/IL134594A/en not_active IP Right Cessation
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