DE122008000051I1 - 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel - Google Patents
2-arylthiazolderivat sowie dieses enthaltendes arzneimittelInfo
- Publication number
- DE122008000051I1 DE122008000051I1 DE122008000051C DE122008000051C DE122008000051I1 DE 122008000051 I1 DE122008000051 I1 DE 122008000051I1 DE 122008000051 C DE122008000051 C DE 122008000051C DE 122008000051 C DE122008000051 C DE 122008000051C DE 122008000051 I1 DE122008000051 I1 DE 122008000051I1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- arylthiazol
- derivative
- optionally protected
- represents hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Residential Or Office Buildings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP33014790 | 1990-11-30 | ||
JP21658691 | 1991-08-02 | ||
PCT/JP1991/001670 WO1992009279A1 (en) | 1990-11-30 | 1991-11-29 | 2-arylthiazole derivative and pharmaceutical composition containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE122008000051I1 true DE122008000051I1 (de) | 2009-02-05 |
Family
ID=26521514
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE122008000051C Pending DE122008000051I1 (de) | 1990-11-30 | 1991-11-29 | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
DE69122084T Expired - Lifetime DE69122084T2 (de) | 1990-11-30 | 1991-11-29 | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69122084T Expired - Lifetime DE69122084T2 (de) | 1990-11-30 | 1991-11-29 | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
Country Status (13)
Country | Link |
---|---|
US (1) | US5614520A (de) |
EP (1) | EP0513379B1 (de) |
JP (1) | JP2725886B2 (de) |
KR (1) | KR100221041B1 (de) |
AT (1) | ATE142494T1 (de) |
AU (1) | AU645867B2 (de) |
CA (1) | CA2073981C (de) |
DE (2) | DE122008000051I1 (de) |
DK (1) | DK0513379T3 (de) |
ES (1) | ES2092580T3 (de) |
HU (1) | HU218942B (de) |
SG (1) | SG86971A1 (de) |
WO (1) | WO1992009279A1 (de) |
Families Citing this family (147)
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US5294630A (en) * | 1992-07-07 | 1994-03-15 | Eli Lilly And Company | Treatment of inflammatory bowel disease |
US5436258A (en) * | 1992-09-09 | 1995-07-25 | Eli Lilly And Company | Prevention of bone resorption |
EP0695742A1 (de) | 1994-08-03 | 1996-02-07 | Hoechst Aktiengesellschaft | Fullerenazirin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung |
AU703609B2 (en) * | 1995-04-07 | 1999-03-25 | Teijin Limited | Protective agent for organ or tissue |
KR970061878A (ko) * | 1996-02-23 | 1997-09-12 | 성재갑 | 신규한 아릴티아졸 유도체, 그의 제조방법 및 그를 유효성분으로 하는 제초제 조성물 |
US6472387B1 (en) | 1996-10-07 | 2002-10-29 | Eli Lilly And Company | Methods of using compounds as neuro-protective agents |
ES2199353T3 (es) * | 1996-10-07 | 2004-02-16 | Eli Lilly And Company | Nuevos compuestos utiles como agentes neuro-protectores. |
ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
ID24564A (id) | 1997-10-06 | 2000-07-27 | Lilly Co Eli | Senyawa-senyawa baru yang berguna sebagai bahan-bahan pelindung saraf |
PT1956014T (pt) * | 1998-06-19 | 2019-04-24 | Teijin Pharma Ltd | Polimorfos de ácido 2-(3-ciano-4-isobutiloxifenil)-4-metil- 5-tiazolecarboxílico e método para a sua produção |
US6083966A (en) | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
NZ526880A (en) | 1998-09-21 | 2005-05-27 | Univ Florida | Antimalarial agents |
US6410562B1 (en) | 1998-12-18 | 2002-06-25 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
US6528652B1 (en) | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
EP2329842A3 (de) * | 2000-05-12 | 2011-07-27 | Immunex Corporation | Interleukin-1 Inhibitoren zur Behandlung von Erkrankungen |
DE10106852A1 (de) | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
JP4917243B2 (ja) * | 2001-05-23 | 2012-04-18 | 日本曹達株式会社 | チアゾール化合物の製造方法 |
SI1488790T1 (sl) * | 2002-03-28 | 2014-09-30 | Teijin Pharma Limited | Trden pripravek, ki vsebuje eno samo kristalno a-obliko derivata tiazolkarboksilne kisline |
US7273866B2 (en) * | 2002-12-20 | 2007-09-25 | Bristol-Myers Squibb Company | 2-aryl thiazole derivatives as KCNQ modulators |
US20040122067A1 (en) * | 2002-12-20 | 2004-06-24 | Lin Zhao | Treatment of chronic heart failure |
US6933308B2 (en) * | 2002-12-20 | 2005-08-23 | Bristol-Myers Squibb Company | Aminoalkyl thiazole derivatives as KCNQ modulators |
JP4532408B2 (ja) | 2003-03-13 | 2010-08-25 | 田辺三菱製薬株式会社 | 腫瘍形成抑制剤 |
US20050027128A1 (en) * | 2003-07-30 | 2005-02-03 | Robbins Timothy A. | Substituted thiazoles |
AU2003270473A1 (en) | 2003-09-09 | 2005-04-27 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
US7037927B2 (en) | 2003-10-16 | 2006-05-02 | Abbott Laboratories | Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US7485657B2 (en) * | 2004-05-12 | 2009-02-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
EP1757610B1 (de) * | 2004-06-14 | 2011-06-08 | Nippon Chemiphar Co., Ltd. | Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor |
KR20070045272A (ko) * | 2004-08-27 | 2007-05-02 | 아스텔라스세이야쿠 가부시키가이샤 | 2-페닐피리딘 유도체 |
US7612108B2 (en) | 2004-08-27 | 2009-11-03 | Astellas Pharma Inc. | 2-phenylthiophene derivative |
EP1799207A2 (de) * | 2004-10-13 | 2007-06-27 | PTC Therapeutics, Inc. | Pyrazol- oder triazolverbindungen und ihre verwendung zur herstellung eines heilmittels zur behandlung durch somatische mutationen bewirkter krankheiten |
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- 1991-11-29 DK DK91920699.5T patent/DK0513379T3/da active
- 1991-11-29 AT AT91920699T patent/ATE142494T1/de not_active IP Right Cessation
- 1991-11-29 DE DE122008000051C patent/DE122008000051I1/de active Pending
- 1991-11-29 EP EP91920699A patent/EP0513379B1/de not_active Expired - Lifetime
- 1991-11-29 HU HU9202265A patent/HU218942B/hu unknown
- 1991-11-29 WO PCT/JP1991/001670 patent/WO1992009279A1/ja active IP Right Grant
- 1991-11-29 AU AU89522/91A patent/AU645867B2/en not_active Expired
- 1991-11-29 JP JP4500083A patent/JP2725886B2/ja not_active Expired - Lifetime
- 1991-11-29 DE DE69122084T patent/DE69122084T2/de not_active Expired - Lifetime
- 1991-11-29 KR KR1019920701809A patent/KR100221041B1/ko not_active IP Right Cessation
- 1991-11-29 CA CA002073981A patent/CA2073981C/en not_active Expired - Lifetime
- 1991-11-29 ES ES91920699T patent/ES2092580T3/es not_active Expired - Lifetime
- 1991-11-29 SG SG9603299A patent/SG86971A1/en unknown
-
1995
- 1995-01-30 US US08/380,214 patent/US5614520A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100221041B1 (ko) | 1999-09-15 |
CA2073981C (en) | 2002-01-08 |
AU8952291A (en) | 1992-06-25 |
DK0513379T3 (da) | 1996-09-30 |
ATE142494T1 (de) | 1996-09-15 |
US5614520A (en) | 1997-03-25 |
HUT63838A (en) | 1993-10-28 |
SG86971A1 (en) | 2002-03-19 |
DE69122084T2 (de) | 1997-04-03 |
AU645867B2 (en) | 1994-01-27 |
WO1992009279A1 (en) | 1992-06-11 |
CA2073981A1 (en) | 1992-05-31 |
HU218942B (hu) | 2001-01-29 |
HU9202265D0 (en) | 1992-10-28 |
EP0513379A1 (de) | 1992-11-19 |
EP0513379B1 (de) | 1996-09-11 |
KR927003052A (ko) | 1992-12-17 |
ES2092580T3 (es) | 1996-12-01 |
JP2725886B2 (ja) | 1998-03-11 |
DE69122084D1 (de) | 1996-10-17 |
EP0513379A4 (en) | 1993-09-01 |
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