NO304516B3 - 1-bifenylmetylimidazolderivater, farmasoytiske preparater og anvendelse av derivatene - Google Patents

1-bifenylmetylimidazolderivater, farmasoytiske preparater og anvendelse av derivatene Download PDF

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Publication number
NO304516B3
NO304516B3 NO19920688A NO920688A NO304516B3 NO 304516 B3 NO304516 B3 NO 304516B3 NO 19920688 A NO19920688 A NO 19920688A NO 920688 A NO920688 A NO 920688A NO 304516 B3 NO304516 B3 NO 304516B3
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NO
Norway
Prior art keywords
reaction
group
singlet
methyl
multiplet
Prior art date
Application number
NO19920688A
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English (en)
Norwegian (no)
Other versions
NO304516B1 (no
NO920688L (no
NO920688D0 (no
Inventor
Hiroaki Yanagisawa
Hiroyuki Koike
Koichi Fujimoto
Takuro Kanazaki
Toshio Sada
Yasuo Shimoji
Yoshiya Amemiya
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27549327&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO304516(B3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of NO920688D0 publication Critical patent/NO920688D0/no
Publication of NO920688L publication Critical patent/NO920688L/no
Priority to NO954507A priority Critical patent/NO304517B1/no
Publication of NO304516B1 publication Critical patent/NO304516B1/no
Publication of NO304516B3 publication Critical patent/NO304516B3/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Dental Preparations (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19920688A 1991-02-21 1992-02-21 1-bifenylmetylimidazolderivater, farmasoytiske preparater og anvendelse av derivatene NO304516B3 (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO954507A NO304517B1 (no) 1991-02-21 1995-11-09 1-bifenylmetylimidazolderivater, farmas°ytiske preparater og anvendelse av derivatene

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2709891 1991-02-21
JP9658891 1991-04-26
JP13488991 1991-06-06
JP16713891 1991-07-08
JP17397291 1991-07-15
JP18484191 1991-07-24

Publications (4)

Publication Number Publication Date
NO920688D0 NO920688D0 (no) 1992-02-21
NO920688L NO920688L (no) 1992-08-24
NO304516B1 NO304516B1 (no) 1999-01-04
NO304516B3 true NO304516B3 (no) 2012-06-11

Family

ID=27549327

Family Applications (6)

Application Number Title Priority Date Filing Date
NO19920688A NO304516B3 (no) 1991-02-21 1992-02-21 1-bifenylmetylimidazolderivater, farmasoytiske preparater og anvendelse av derivatene
NO954507A NO304517B1 (no) 1991-02-21 1995-11-09 1-bifenylmetylimidazolderivater, farmas°ytiske preparater og anvendelse av derivatene
NO2003009C NO2003009I2 (en) 1991-02-21 2003-11-27 1-Bifenylmetylimidazol-derivater, farmasoytiske preparater og anvendelse av derivatene
NO2006012C NO2006012I1 (no) 1991-02-21 2006-10-09 Kombinasjon av olmesartan medoximil, eventuelt i form av et farmasoytisk akseptabelt salt, og hydroklortiazid
NO2009019C NO2009019I1 (no) 1991-02-21 2009-09-11 Amiodipinbesylat
NO2011013C NO2011013I1 (no) 1991-02-21 2011-08-10 Kombinasjon av olmesartan medoksomil, eventuelt i form av et farmasøytisk akseptabelt salt, og amlodipinbesylat og hydroklortiazid

Family Applications After (5)

Application Number Title Priority Date Filing Date
NO954507A NO304517B1 (no) 1991-02-21 1995-11-09 1-bifenylmetylimidazolderivater, farmas°ytiske preparater og anvendelse av derivatene
NO2003009C NO2003009I2 (en) 1991-02-21 2003-11-27 1-Bifenylmetylimidazol-derivater, farmasoytiske preparater og anvendelse av derivatene
NO2006012C NO2006012I1 (no) 1991-02-21 2006-10-09 Kombinasjon av olmesartan medoximil, eventuelt i form av et farmasoytisk akseptabelt salt, og hydroklortiazid
NO2009019C NO2009019I1 (no) 1991-02-21 2009-09-11 Amiodipinbesylat
NO2011013C NO2011013I1 (no) 1991-02-21 2011-08-10 Kombinasjon av olmesartan medoksomil, eventuelt i form av et farmasøytisk akseptabelt salt, og amlodipinbesylat og hydroklortiazid

Country Status (23)

Country Link
EP (2) EP0545912B1 (xx)
JP (1) JPH07121918B2 (xx)
KR (1) KR0128289B1 (xx)
CN (3) CN1045770C (xx)
AT (2) ATE200777T1 (xx)
CA (2) CA2229000C (xx)
CZ (1) CZ289194B6 (xx)
DE (6) DE122009000024I1 (xx)
DK (2) DK0503785T3 (xx)
ES (2) ES2156866T3 (xx)
FI (2) FI112942B3 (xx)
GR (2) GR3035909T3 (xx)
HK (2) HK1011361A1 (xx)
HU (3) HU223338B1 (xx)
IE (1) IE920540A1 (xx)
IL (3) IL101034A (xx)
IS (1) IS1756B (xx)
LU (4) LU91056I2 (xx)
NL (3) NL300133I2 (xx)
NO (6) NO304516B3 (xx)
NZ (1) NZ241681A (xx)
PT (2) PT545912E (xx)
RU (1) RU2128173C1 (xx)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
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