US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
EP2206723A1
(de)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modulare DNA-bindende Domänen
|
US20110239315A1
(en)
|
2009-01-12 |
2011-09-29 |
Ulla Bonas |
Modular dna-binding domains and methods of use
|
JP5798116B2
(ja)
*
|
2009-06-30 |
2015-10-21 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
生物活性のあるヌクレアーゼの迅速なスクリーニングおよびヌクレアーゼ修飾細胞の単離
|
US8586363B2
(en)
|
2009-12-10 |
2013-11-19 |
Regents Of The University Of Minnesota |
TAL effector-mediated DNA modification
|
JP2013518602A
(ja)
*
|
2010-02-09 |
2013-05-23 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
部分的に一本鎖のドナー分子による標的化ゲノム改変
|
US8771985B2
(en)
*
|
2010-04-26 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Genome editing of a Rosa locus using zinc-finger nucleases
|
EP3156062A1
(de)
|
2010-05-17 |
2017-04-19 |
Sangamo BioSciences, Inc. |
Neuartige dna-bindende proteine und verwendungen davon
|
NZ708078A
(en)
|
2010-06-02 |
2017-01-27 |
Evolva Nutrition Inc |
Recombinant production of steviol glycosides
|
EP2392208B1
(de)
*
|
2010-06-07 |
2016-05-04 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusionsproteine, die eine DNA-Bindungsdomäne eines TAL-Effektorproteins und eine unspezifische Spaltungsdomäne einer Restriktionsnuklease umfassen, und deren Verwendung
|
US20110201118A1
(en)
*
|
2010-06-14 |
2011-08-18 |
Iowa State University Research Foundation, Inc. |
Nuclease activity of tal effector and foki fusion protein
|
EP2596011B1
(de)
|
2010-07-21 |
2018-10-03 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur veränderung eines hla-locus
|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
KR20140046408A
(ko)
|
2011-02-25 |
2014-04-18 |
리컴비네틱스 인코포레이티드 |
유전자 변형 동물 및 이의 생산방법
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
KR101982360B1
(ko)
*
|
2011-04-05 |
2019-05-24 |
셀렉티스 |
콤팩트 tale-뉴클레아제의 발생 방법 및 이의 용도
|
WO2012149470A1
(en)
*
|
2011-04-27 |
2012-11-01 |
Amyris, Inc. |
Methods for genomic modification
|
ES2657825T3
(es)
|
2011-06-06 |
2018-03-07 |
Bayer Cropscience Nv |
Métodos y medios para modificar el genoma de una planta en un sitio preseleccionado
|
EP3461896B1
(de)
|
2011-07-15 |
2023-11-29 |
The General Hospital Corporation |
Verfahren zur transkription einer aktivatorähnlichen effektoranordnung
|
CA2853829C
(en)
|
2011-07-22 |
2023-09-26 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
WO2013016446A2
(en)
|
2011-07-25 |
2013-01-31 |
Sangamo Biosciences, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
MX365219B
(es)
*
|
2011-07-27 |
2019-05-27 |
The Broad Inst Inc Star |
Uso de una composición en un método para inhibir el crecimiento del carcinoma de células escamosas de cabeza y cuello (hnscc).
|
WO2013017950A1
(en)
*
|
2011-07-29 |
2013-02-07 |
Cellectis |
High throughput method for assembly and cloning polynucleotides comprising highly similar polynucleotidic modules
|
WO2013019745A1
(en)
*
|
2011-07-29 |
2013-02-07 |
Georgia Health Sciences University |
Methods and compositions for genetically modifiying cells
|
CN102787125B
(zh)
*
|
2011-08-05 |
2013-12-04 |
北京大学 |
一种构建tale重复序列的方法
|
BR112014003037B1
(pt)
|
2011-08-08 |
2022-04-05 |
Evolva Sa |
Hospedeiro recombinante e método para produzir um glicosídeo de esteviol
|
MX348003B
(es)
|
2011-08-22 |
2017-03-08 |
Bayer Cropscience Nv |
Metodos y medios para modificar un genoma vegetal.
|
CN103917644A
(zh)
|
2011-09-21 |
2014-07-09 |
桑格摩生物科学股份有限公司 |
调控转基因表达的方法和组合物
|
WO2013050593A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013050611A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013050318A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013053686A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
WO2013053711A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
CA2851563A1
(en)
|
2011-10-12 |
2013-04-18 |
Bayer Cropscience Ag |
Plants with decreased activity of a starch dephosphorylating enzyme
|
AU2013201323A1
(en)
|
2011-10-12 |
2013-05-02 |
Bayer Cropscience Ag |
Plants with decreased activity of a starch dephosphorylating enzyme
|
EP2784157B1
(de)
|
2011-10-21 |
2019-09-18 |
Kyushu University, National University Corporation |
Entwurfsverfahren für ein rns-bindendes protein mit einem ppr-motiv und verwendung davon
|
JP6188703B2
(ja)
*
|
2011-10-27 |
2017-08-30 |
サンガモ セラピューティクス, インコーポレイテッド |
Hprt遺伝子座を修飾するための方法および組成物
|
US20150159166A1
(en)
|
2011-10-31 |
2015-06-11 |
Pioneer Hi Bred International Inc |
Plant drought tolerance and nitrogen use efficiency by reducing plant sensitivity to ethylene
|
EP2780460B1
(de)
*
|
2011-11-16 |
2018-07-11 |
Sangamo Therapeutics, Inc. |
Modifizierte dna-bindende proteine und verwendungen davon
|
US10801017B2
(en)
*
|
2011-11-30 |
2020-10-13 |
The Broad Institute, Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
US8450107B1
(en)
|
2011-11-30 |
2013-05-28 |
The Broad Institute Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
US20130137173A1
(en)
*
|
2011-11-30 |
2013-05-30 |
Feng Zhang |
Nucleotide-specific recognition sequences for designer tal effectors
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
EP2788033B1
(de)
|
2011-12-05 |
2017-05-31 |
Factor Bioscience Inc. |
Verfahren und produkte zur transfektion von zellen
|
US11458157B2
(en)
|
2011-12-16 |
2022-10-04 |
Targetgene Biotechnologies Ltd. |
Compositions and methods for modifying a predetermined target nucleic acid sequence
|
DE102011122267A1
(de)
|
2011-12-23 |
2013-06-27 |
Kws Saat Ag |
Neue aus Pflanzen stammende cis-regulatorische Elemente für die Entwicklung Pathogen-responsiver chimärer Promotoren
|
WO2013101877A2
(en)
|
2011-12-29 |
2013-07-04 |
Iowa State University Research Foundation, Inc. |
Genetically modified plants with resistance to xanthomonas and other bacterial plant pathogens
|
GB201122458D0
(en)
|
2011-12-30 |
2012-02-08 |
Univ Wageningen |
Modified cascade ribonucleoproteins and uses thereof
|
EP2612918A1
(de)
|
2012-01-06 |
2013-07-10 |
BASF Plant Science Company GmbH |
In planta-Rekombination
|
US20150203864A1
(en)
|
2012-03-13 |
2015-07-23 |
University Of Guelph |
Myb55 promoter and use thereof
|
CN104302773A
(zh)
|
2012-03-13 |
2015-01-21 |
圭尔夫大学 |
增加植物对热胁迫的耐受性及氨基酸含量的方法
|
EP2825190B1
(de)
|
2012-03-15 |
2016-11-30 |
Cellectis |
Di-rückstände mit variabler wiederholung zum anzielen von nukleotiden
|
EP2828384B1
(de)
|
2012-03-23 |
2018-05-09 |
Cellectis |
Verfahren zur überwindung der empfindlichkeit gegenüber chemischen dna-modifikationen von dna-bindenden domänen synthetischer tale
|
CN102628037B
(zh)
*
|
2012-03-31 |
2013-07-24 |
西南大学 |
家蚕油蚕基因BmBlos2遗传改造系统及其制备方法和应用
|
WO2013152220A2
(en)
*
|
2012-04-04 |
2013-10-10 |
Life Technologies Corporation |
Tal-effector assembly platform, customized services, kits and assays
|
DK2839013T3
(da)
|
2012-04-18 |
2020-09-14 |
Univ Leland Stanford Junior |
Ikke-disruptiv-gen-targetering
|
CN104245940A
(zh)
|
2012-04-23 |
2014-12-24 |
拜尔作物科学公司 |
植物中的靶向基因组工程
|
ES2683071T3
(es)
|
2012-04-25 |
2018-09-24 |
Regeneron Pharmaceuticals, Inc. |
Direccionamiento mediado por nucleasas con grandes vectores de direccionamiento
|
WO2013163628A2
(en)
|
2012-04-27 |
2013-10-31 |
Duke University |
Genetic correction of mutated genes
|
AU2013256240B2
(en)
|
2012-05-02 |
2018-09-20 |
Corteva Agriscience Llc |
Targeted modification of malate dehydrogenase
|
CN104471067B
(zh)
*
|
2012-05-07 |
2020-08-14 |
桑格摩生物治疗股份有限公司 |
用于核酸酶介导的转基因靶向整合的方法和组合物
|
US11120889B2
(en)
|
2012-05-09 |
2021-09-14 |
Georgia Tech Research Corporation |
Method for synthesizing a nuclease with reduced off-site cleavage
|
EP2855666B1
(de)
*
|
2012-05-25 |
2019-12-04 |
Cellectis |
Verwendung von prä-alpha-t oder einer funktionellen variante davon zur vermehrung von t-zellen mit tcr-alpha-mangel
|
US9605274B2
(en)
|
2012-05-25 |
2017-03-28 |
Evolutionary Genomics, Inc. |
Dirigent gene EG261 and its orthologs and paralogs and their uses for pathogen resistance in plants
|
BR112014029381B1
(pt)
|
2012-05-25 |
2022-09-13 |
Eg Crop Science, Inc |
Método para produzir uma planta de soja recombinante, método para produzir semente de soja híbrida, método para reprodução de plantas de soja e constructo
|
DK2800811T3
(en)
|
2012-05-25 |
2017-07-17 |
Univ Vienna |
METHODS AND COMPOSITIONS FOR RNA DIRECTIVE TARGET DNA MODIFICATION AND FOR RNA DIRECTIVE MODULATION OF TRANSCRIPTION
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
WO2013182910A2
(en)
|
2012-06-05 |
2013-12-12 |
Cellectis |
New transcription activator-like effector (tale) fusion protein
|
US9815877B2
(en)
|
2012-06-07 |
2017-11-14 |
The Children's Hospital Of Philadelphia |
Controlled gene expression methods
|
BR112014031080A2
(pt)
|
2012-06-12 |
2018-05-08 |
Genentech Inc |
métodos e composições de geração de alelos knock-out condicionais.
|
WO2013188291A2
(en)
|
2012-06-15 |
2013-12-19 |
E. I. Du Pont De Nemours And Company |
Methods and compositions involving als variants with native substrate preference
|
BR112014031891A2
(pt)
|
2012-06-19 |
2017-08-01 |
Univ Minnesota |
direcionamento genético nas plantas utilizando vírus de dna
|
AR091482A1
(es)
*
|
2012-06-21 |
2015-02-04 |
Recombinetics Inc |
Celulas modificadas geneticamente y metodos par su obtencion
|
WO2013191769A1
(en)
*
|
2012-06-22 |
2013-12-27 |
Mayo Foundation For Medical Education And Research |
Genome editing
|
US20160281103A1
(en)
|
2012-07-06 |
2016-09-29 |
National Institute Of Agrobiological Sciences |
Wheat with increased number of grains and method for producing the same, and agent for increasing the number of wheat grains
|
US20140072961A1
(en)
*
|
2012-07-11 |
2014-03-13 |
University of Nevada, Las Vegas |
Method of Genome Surgery with Paired, Permeant Endonuclease Excision
|
EP3196301B1
(de)
|
2012-07-11 |
2018-10-17 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur behandlung von monogener krankheiten
|
JP6329537B2
(ja)
|
2012-07-11 |
2018-05-23 |
サンガモ セラピューティクス, インコーポレイテッド |
生物学的薬剤の送達のための方法および組成物
|
EP2687605A1
(de)
|
2012-07-19 |
2014-01-22 |
Biogemma |
Verfahren zur Durchführung einer homologen Rekombination
|
EP2877488B1
(de)
|
2012-07-24 |
2021-02-24 |
Cellectis |
Neue modulare basenspezifische nukleinsäurebindende domänen aus burkholderia-rhizoxinica-proteinen
|
JP2015527889A
(ja)
*
|
2012-07-25 |
2015-09-24 |
ザ ブロード インスティテュート, インコーポレイテッド |
誘導可能なdna結合タンパク質およびゲノム撹乱ツール、ならびにそれらの適用
|
US10058078B2
(en)
|
2012-07-31 |
2018-08-28 |
Recombinetics, Inc. |
Production of FMDV-resistant livestock by allele substitution
|
DK2890780T3
(da)
|
2012-08-29 |
2020-09-21 |
Sangamo Therapeutics Inc |
Fremgangsmåder og sammensætninger til behandling af en genetisk tilstand
|
EP2893016B1
(de)
*
|
2012-09-03 |
2019-06-19 |
Cellectis |
Verfahren zur modulierung einer tal-spezifität
|
KR102357105B1
(ko)
*
|
2012-09-04 |
2022-02-08 |
더 스크립스 리서치 인스티튜트 |
표적화된 바인딩 특이도를 갖는 키메라 폴리펩타이드들
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
JP6775953B2
(ja)
|
2012-09-07 |
2020-10-28 |
ダウ アグロサイエンシィズ エルエルシー |
Fad3性能座および標的化切断を誘導可能である対応する標的部位特異的結合タンパク質
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
EP3257952B1
(de)
|
2012-09-11 |
2020-02-12 |
Life Technologies Corporation |
Nukleinsäureamplifikation
|
WO2014043143A1
(en)
|
2012-09-11 |
2014-03-20 |
Life Technologies Corporation |
Nucleic acid amplification
|
US20150267176A1
(en)
|
2012-10-12 |
2015-09-24 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
WO2014070887A1
(en)
*
|
2012-10-30 |
2014-05-08 |
Recombinetics, Inc. |
Control of sexual maturation in animals
|
US20150291967A1
(en)
|
2012-10-31 |
2015-10-15 |
Luc Mathis |
Coupling herbicide resistance with targeted insertion of transgenes in plants
|
RU2019143431A
(ru)
|
2012-11-01 |
2020-04-28 |
Фэктор Байосайенс Инк. |
Способы и продукты для экспрессии белков в клетках
|
BR112015009967B1
(pt)
|
2012-11-01 |
2022-07-12 |
Medicago Inc. |
Método para a produção de um polipeptídeo terapêutico
|
AU2013348113A1
(en)
*
|
2012-11-20 |
2015-06-11 |
J.R. Simplot Company |
TAL-mediated transfer DNA insertion
|
US9255250B2
(en)
|
2012-12-05 |
2016-02-09 |
Sangamo Bioscience, Inc. |
Isolated mouse or human cell having an exogenous transgene in an endogenous albumin gene
|
KR102243092B1
(ko)
|
2012-12-06 |
2021-04-22 |
시그마-알드리치 컴퍼니., 엘엘씨 |
Crispr-기초된 유전체 변형과 조절
|
CN103013954B
(zh)
*
|
2012-12-17 |
2014-03-05 |
中国科学院遗传与发育生物学研究所 |
水稻基因badh2的定点敲除系统及其应用
|
US9708589B2
(en)
|
2012-12-18 |
2017-07-18 |
Monsanto Technology Llc |
Compositions and methods for custom site-specific DNA recombinases
|
WO2014100525A2
(en)
|
2012-12-21 |
2014-06-26 |
Pioneer Hi-Bred International, Inc. |
Compositions and methods for auxin-analog conjugation
|
ES2673864T3
(es)
*
|
2012-12-21 |
2018-06-26 |
Cellectis |
Patatas con endulzamiento inducido en frío reducido
|
EP2954058B1
(de)
|
2013-02-06 |
2021-03-31 |
Evolva SA |
Verfahren zur verbesserten herstellung von rebaudiosid-d und rebaudiosid-m
|
EP3623463B1
(de)
*
|
2013-02-07 |
2021-10-20 |
The General Hospital Corporation |
Tale-transkriptionsaktivatoren
|
BR112015019160A2
(pt)
|
2013-02-11 |
2017-08-22 |
Dalgaard Mikkelsen Michael |
Produção de glicosídeos de esteviol em hospedeiros recombinantes
|
CN103319574A
(zh)
*
|
2013-02-16 |
2013-09-25 |
清华大学 |
分离的多肽及其应用
|
JP6475172B2
(ja)
|
2013-02-20 |
2019-02-27 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
ラットの遺伝子組換え
|
US20150353885A1
(en)
|
2013-02-21 |
2015-12-10 |
Cellectis |
Method to counter-select cells or organisms by linking loci to nuclease components
|
US10227610B2
(en)
|
2013-02-25 |
2019-03-12 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
WO2014134412A1
(en)
*
|
2013-03-01 |
2014-09-04 |
Regents Of The University Of Minnesota |
Talen-based gene correction
|
BR112015022742A2
(pt)
|
2013-03-11 |
2018-11-27 |
Pionner Hi Bred Int Inc |
métodos e composições que empregam um domínio de estabilização dependente de sulfonilureia
|
AU2014236162A1
(en)
|
2013-03-14 |
2015-09-17 |
Arzeda Corp. |
Compositions having dicamba decarboxylase activity and methods of use
|
EP2971167B1
(de)
|
2013-03-14 |
2019-07-31 |
Caribou Biosciences, Inc. |
Zusammensetzungen und verfahren zum targeting von nukleinsäuren durch nukleinsäuren
|
WO2014153234A1
(en)
|
2013-03-14 |
2014-09-25 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
JP2016512048A
(ja)
*
|
2013-03-15 |
2016-04-25 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
CRISPR/Casシステムを使用した植物ゲノム操作
|
US10793867B2
(en)
|
2013-03-15 |
2020-10-06 |
Monsanto Technology, Llc |
Methods for targeted transgene-integration using custom site-specific DNA recombinases
|
CN105246324B
(zh)
*
|
2013-03-15 |
2018-08-28 |
塞尔克蒂斯股份有限公司 |
通过靶向敲除fad2-1a/1b基因来改良大豆油成分
|
US11039586B2
(en)
|
2013-03-15 |
2021-06-22 |
Monsanto Technology Llc |
Creation and transmission of megaloci
|
US10113162B2
(en)
|
2013-03-15 |
2018-10-30 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes
|
US20140363561A1
(en)
*
|
2013-03-15 |
2014-12-11 |
J.R. Simplot Company |
Tal-mediated transfer dna insertion
|
WO2014161821A1
(en)
|
2013-04-02 |
2014-10-09 |
Bayer Cropscience Nv |
Targeted genome engineering in eukaryotes
|
KR102192599B1
(ko)
|
2013-04-05 |
2020-12-18 |
다우 아그로사이언시즈 엘엘씨 |
식물의 게놈 내의 외인성 서열의 통합을 위한 방법 및 조성물
|
RS62263B1
(sr)
|
2013-04-16 |
2021-09-30 |
Regeneron Pharma |
Ciljana modifikacija genoma pacova
|
CN105008536A
(zh)
*
|
2013-04-16 |
2015-10-28 |
深圳华大基因科技服务有限公司 |
分离的寡核苷酸及其用途
|
KR102606057B1
(ko)
|
2013-04-22 |
2023-11-23 |
고쿠리쓰다이가쿠호진 규슈다이가쿠 |
피피알 단백질을 이용하여 dna 염기 또는 특정 염기서열을 가지는 dna를 동정, 인식 또는 표적화하는 방법
|
EP2796558A1
(de)
|
2013-04-23 |
2014-10-29 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Verbessertes Gen-Targeting und Nucleinsäureträgermoleküle, insbesondere zur Verwendung bei Pflanzen
|
CN103233004B
(zh)
*
|
2013-04-28 |
2015-04-29 |
新疆农垦科学院 |
一种人工dna分子及检测目标基因表达的方法
|
WO2014186435A2
(en)
|
2013-05-14 |
2014-11-20 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for reducing neointima formation
|
US20160145631A1
(en)
*
|
2013-06-14 |
2016-05-26 |
Cellectis |
Methods for non-transgenic genome editing in plants
|
EP4245853A3
(de)
|
2013-06-17 |
2023-10-18 |
The Broad Institute, Inc. |
Optimierte crispr-cas-doppel-nickase-systeme, verfahren und zusammensetzungen zur sequenzmanipulation
|
CA2915842C
(en)
|
2013-06-17 |
2022-11-29 |
The Broad Institute, Inc. |
Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy
|
EP2818867A1
(de)
|
2013-06-27 |
2014-12-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
An mindestens ein Nucleinsäuremolekül konjugierte Antikörper und deren Verwendung in Multiplex-Immunnachweis-Assays
|
WO2015002780A1
(en)
*
|
2013-07-01 |
2015-01-08 |
The Board Of Regents Of The University Of Texas System |
Transcription activator-like effector (tale) libraries and methods of synthesis and use
|
US10563225B2
(en)
|
2013-07-26 |
2020-02-18 |
President And Fellows Of Harvard College |
Genome engineering
|
ES2915377T3
(es)
|
2013-08-02 |
2022-06-22 |
Enevolv Inc |
Procedimientos y células huésped para ingeniería genómica, de vías y biomolécular
|
JP5931022B2
(ja)
|
2013-08-09 |
2016-06-08 |
国立大学法人広島大学 |
Dna結合ドメインを含むポリペプチド
|
US10006011B2
(en)
|
2013-08-09 |
2018-06-26 |
Hiroshima University |
Polypeptide containing DNA-binding domain
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
DE102013014637A1
(de)
|
2013-09-04 |
2015-03-05 |
Kws Saat Ag |
HELMlNTHOSPORlUM TURClCUM-RESlSTENTE PFLANZE
|
PL3041345T3
(pl)
|
2013-09-04 |
2024-07-22 |
KWS SAAT SE & Co. KGaA |
Roślina odporna na helminthosporium turcicum
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
CA2923844C
(en)
|
2013-09-11 |
2022-07-26 |
Arsia Therapeutics, Inc. |
Liquid protein formulations containing organophosphates
|
US10526616B2
(en)
*
|
2013-09-23 |
2020-01-07 |
Rensselaer Polytechnic Institute |
Nanoparticle-mediated gene delivery, genomic editing and ligand-targeted modification in various cell populations
|
WO2015057600A1
(en)
|
2013-10-18 |
2015-04-23 |
E. I. Du Pont De Nemours And Company |
Glyphosate-n-acetyltransferase (glyat) sequences and methods of use
|
AP2016009207A0
(en)
|
2013-10-25 |
2016-05-31 |
Livestock Improvement Corp Ltd |
Genetic markers and uses therefor
|
WO2015066647A2
(en)
|
2013-11-03 |
2015-05-07 |
The Regents Of The University Of California |
Ionic liquids for transdermal drug delivery
|
KR102269769B1
(ko)
|
2013-11-04 |
2021-06-28 |
코르테바 애그리사이언스 엘엘씨 |
최적 메이즈 유전자좌
|
NZ746567A
(en)
|
2013-11-04 |
2019-09-27 |
Dow Agrosciences Llc |
Optimal soybean loci
|
EP3066109A4
(de)
|
2013-11-04 |
2017-11-29 |
Dow AgroSciences LLC |
Optimale sojabohnen-loci
|
CA2928855A1
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal maize loci
|
WO2015068785A1
(ja)
|
2013-11-06 |
2015-05-14 |
国立大学法人広島大学 |
核酸挿入用ベクター
|
US11326209B2
(en)
*
|
2013-11-07 |
2022-05-10 |
Massachusetts Institute Of Technology |
Cell-based genomic recorded accumulative memory
|
EP2878667A1
(de)
|
2013-11-29 |
2015-06-03 |
Institut Pasteur |
TAL-Effektormittel zur partiellen oder vollständigen Deletion von DNA-Tandem-Repeats
|
CN103710360A
(zh)
*
|
2013-12-03 |
2014-04-09 |
南方医科大学珠江医院 |
提高HepGL肝癌细胞氨基甲酰磷酸合成酶表达的方法
|
RU2725520C2
(ru)
|
2013-12-11 |
2020-07-02 |
Регенерон Фармасьютикалс, Инк. |
Способы и композиции для направленной модификации генома
|
EP3460063B1
(de)
|
2013-12-11 |
2024-03-13 |
Regeneron Pharmaceuticals, Inc. |
Verfahren und zusammensetzungen zur gezielten modifikation eines genoms
|
JP6793547B2
(ja)
|
2013-12-12 |
2020-12-02 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
最適化機能CRISPR−Cas系による配列操作のための系、方法および組成物
|
WO2015089462A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for genome editing
|
CA2932472A1
(en)
|
2013-12-12 |
2015-06-18 |
Massachusetts Institute Of Technology |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
CN106030310B
(zh)
|
2013-12-13 |
2019-01-04 |
通用医疗公司 |
可溶性高分子量(hmw)tau种类及其应用
|
WO2015092460A1
(en)
|
2013-12-18 |
2015-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New gene mutations for the diagnosis of arthrogryposis multiplex congenita and congenital peripheral neuropathies disease
|
KR102274445B1
(ko)
|
2013-12-19 |
2021-07-08 |
아미리스 인코퍼레이티드 |
게놈 삽입을 위한 방법
|
US10233456B2
(en)
*
|
2014-01-30 |
2019-03-19 |
The Board Of Trustees Of The University Of Arkansas |
Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
|
MX2016009771A
(es)
|
2014-01-31 |
2016-11-14 |
Factor Bioscience Inc |
Metodos y productos para la produccion y administracion de acido nucleico.
|
WO2015117081A2
(en)
|
2014-02-03 |
2015-08-06 |
Sangamo Biosciences, Inc. |
Methods and compositions for treatment of a beta thalessemia
|
CN104844696A
(zh)
*
|
2014-02-19 |
2015-08-19 |
北京大学 |
一种转录激活子样效应因子功能蛋白设计、合成及其应用
|
TW201538518A
(zh)
|
2014-02-28 |
2015-10-16 |
Dow Agrosciences Llc |
藉由嵌合基因調控元件所賦予之根部特異性表現
|
CN111471675A
(zh)
|
2014-03-05 |
2020-07-31 |
国立大学法人神户大学 |
特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体
|
AU2015231231B2
(en)
|
2014-03-21 |
2021-09-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Genome editing without nucleases
|
EP3122877B1
(de)
|
2014-03-26 |
2023-03-22 |
University of Maryland, College Park |
Gezielte genomänderung in zygoten von grossen haustieren
|
WO2015153889A2
(en)
*
|
2014-04-02 |
2015-10-08 |
University Of Florida Research Foundation, Incorporated |
Materials and methods for the treatment of latent viral infection
|
US9522936B2
(en)
|
2014-04-24 |
2016-12-20 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (TALE) proteins
|
CN111647627A
(zh)
|
2014-04-28 |
2020-09-11 |
重组股份有限公司 |
多重基因编辑
|
CN104611365B
(zh)
*
|
2014-07-17 |
2017-06-16 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
US10563207B2
(en)
|
2014-04-30 |
2020-02-18 |
Tsinghua University |
Modular construction of synthetic gene circuits in mammalian cells using TALE transcriptional repressors
|
WO2015165276A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒
|
DE102014106327A1
(de)
|
2014-05-07 |
2015-11-12 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
TAL-Effektornuklease zum gezielten Knockout des HIV-Korezeptors CCR5
|
EP3140269B1
(de)
|
2014-05-09 |
2023-11-29 |
Yale University |
Hyperverzweigte polyglycerolbeschichtete partikel und verfahren zur herstellung und verwendung davon
|
US11918695B2
(en)
|
2014-05-09 |
2024-03-05 |
Yale University |
Topical formulation of hyperbranched polymer-coated particles
|
EP3142707A4
(de)
|
2014-05-13 |
2018-02-21 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur vorbeugung oder behandlung einer krankheit
|
EP3708671A1
(de)
|
2014-06-06 |
2020-09-16 |
Regeneron Pharmaceuticals, Inc. |
Verfahren und zusammensetzungen für die veränderung eines ziellokus
|
WO2015188870A1
(en)
|
2014-06-12 |
2015-12-17 |
Sesvanderhave N.V. |
Use of selectable marker gene in sugar beet protoplasts transformation method and system
|
EP3155001A1
(de)
|
2014-06-12 |
2017-04-19 |
SESVanderHave N.V. |
Verfahren zur transformation von zuckerrübenprotoplasten durch talenplattformtechnologie
|
WO2015193858A1
(en)
|
2014-06-20 |
2015-12-23 |
Cellectis |
Potatoes with reduced granule-bound starch synthase
|
CA2953499C
(en)
|
2014-06-23 |
2023-10-24 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated dna assembly
|
US9902971B2
(en)
|
2014-06-26 |
2018-02-27 |
Regeneron Pharmaceuticals, Inc. |
Methods for producing a mouse XY embryonic (ES) cell line capable of producing a fertile XY female mouse in an F0 generation
|
WO2016000237A1
(en)
|
2014-07-03 |
2016-01-07 |
Pioneer Overseas Corporation |
Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
SG11201700651RA
(en)
|
2014-08-11 |
2017-02-27 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
CN107429241A
(zh)
|
2014-08-14 |
2017-12-01 |
北京百奥赛图基因生物技术有限公司 |
Dna敲入系统
|
CN105367628B
(zh)
*
|
2014-08-19 |
2019-07-26 |
深圳华大基因农业控股有限公司 |
一对高效编辑水稻waxy基因的talen其识别打靶位点及其应用
|
CN105367631B
(zh)
*
|
2014-08-25 |
2019-05-14 |
深圳华大基因科技有限公司 |
一种转录激活子样效应因子核酸酶及其编码基因和应用
|
MX2017002931A
(es)
|
2014-09-07 |
2017-05-30 |
Selecta Biosciences Inc |
Metodos y composiciones para atenuar respuestas inmunes anti-vector de transferencia viral.
|
CN107109358B
(zh)
|
2014-09-09 |
2022-08-02 |
埃沃尔瓦公司 |
在重组宿主中生产甜菊醇糖苷
|
KR101528812B1
(ko)
*
|
2014-09-18 |
2015-06-15 |
강원대학교산학협력단 |
SETDB1 HMTase 발현 저해방법
|
CN105440111B
(zh)
*
|
2014-09-30 |
2019-08-13 |
深圳华大基因研究院 |
一对转录激活子样效应因子核酸酶及其编码序列与应用
|
WO2016054259A1
(en)
|
2014-10-01 |
2016-04-07 |
Arsia Therapeutics, Inc. |
Polysaccharide and nucleic acid formulations containing viscosity-lowering agents
|
CN104357440B
(zh)
*
|
2014-10-09 |
2017-06-13 |
中山大学 |
一对靶向斑马鱼Forkhead box n1基因的Talen识别序列及其mRNA制备方法
|
EP3204496A1
(de)
|
2014-10-10 |
2017-08-16 |
Editas Medicine, Inc. |
Zusammensetzungen und verfahren zur förderung einer homologiegerichteten reparatur
|
ES2741387T3
(es)
|
2014-10-15 |
2020-02-10 |
Regeneron Pharma |
Métodos y composiciones para generar o mantener células pluripotentes
|
WO2016066671A1
(en)
|
2014-10-29 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating resistant cancers using progastrin inhibitors
|
JP6153180B2
(ja)
|
2014-11-04 |
2017-06-28 |
国立大学法人神戸大学 |
脱塩基反応により標的化したdna配列に特異的に変異を導入する、ゲノム配列の改変方法、並びにそれに用いる分子複合体
|
CN107532142A
(zh)
*
|
2014-11-11 |
2018-01-02 |
应用干细胞有限公司 |
使用同源重组改造间充质干细胞
|
DE102014016667B4
(de)
|
2014-11-12 |
2024-03-07 |
Kws Saat Se |
Haploideninduktoren
|
EP3218393A1
(de)
|
2014-11-12 |
2017-09-20 |
Recombinetics, Inc. |
Heterozygote modifikationen von tumorsuppressorgenen und schweinemodell von neurofibromatose typ1
|
US20160138040A1
(en)
*
|
2014-11-13 |
2016-05-19 |
Cellectis |
Brassica engineered to confer herbicide tolerance
|
WO2016094867A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Protected guide rnas (pgrnas)
|
WO2016100333A1
(en)
|
2014-12-15 |
2016-06-23 |
Syngenta Participations Ag |
Pesticidal microrna carriers and use thereof
|
WO2016100819A1
(en)
|
2014-12-19 |
2016-06-23 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modification through single-step multiple targeting
|
ES2785329T3
(es)
|
2014-12-23 |
2020-10-06 |
Syngenta Participations Ag |
Métodos y composiciones para identificar y enriquecer células que comprenden modificaciones genómicas específicas para el sitio
|
WO2016118560A1
(en)
*
|
2015-01-20 |
2016-07-28 |
Mayo Foundation For Medical Education And Research |
Methods and materials for assembling nucleic acid constructs
|
CA2974381A1
(en)
|
2015-01-26 |
2016-08-04 |
Fate Therapeutics, Inc. |
Methods and compositions for inducing hematopoietic cell differentiation
|
WO2016120486A1
(en)
|
2015-01-30 |
2016-08-04 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
EP3253877A1
(de)
*
|
2015-02-02 |
2017-12-13 |
Cellectis |
Agrobakterium-vermittelte genommodifizierung ohne t-dna-integration
|
WO2016124918A1
(en)
|
2015-02-03 |
2016-08-11 |
The Institute Of Genetics And Developmental Biology |
Plants with increased seed size
|
WO2016124920A1
(en)
|
2015-02-03 |
2016-08-11 |
The Institute Of Genetics And Developmental Biology |
Rice plants with altered seed phenotype and quality
|
JP6929791B2
(ja)
|
2015-02-09 |
2021-09-01 |
デューク ユニバーシティ |
エピゲノム編集のための組成物および方法
|
WO2016128523A1
(en)
|
2015-02-12 |
2016-08-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the responsiveness of a patient affected with malignant hematological disease to chemotherapy treatment and methods of treatment of such disease
|
EP3543339A1
(de)
|
2015-02-13 |
2019-09-25 |
Factor Bioscience Inc. |
Nukleinsäureprodukte und verabreichungsverfahren dafür
|
JP6590333B2
(ja)
*
|
2015-02-26 |
2019-10-16 |
学校法人東京理科大学 |
Dna結合ドメイン組込み用ベクターおよびそのセット、融合タンパク質コーディングベクターおよびそのセットならびにその製造方法、デスティネーションベクター、植物細胞用発現ベクターおよびその製造方法、植物細胞用発現ベクター作製用キット、形質転換方法、ならびにゲノム編集方法
|
US11261466B2
(en)
|
2015-03-02 |
2022-03-01 |
Sinai Health System |
Homologous recombination factors
|
WO2016142427A1
(en)
|
2015-03-10 |
2016-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method ank kit for reprogramming somatic cells
|
AU2016239037B2
(en)
*
|
2015-03-16 |
2022-04-21 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Method of applying non-genetic substance to perform site-directed reform of plant genome
|
WO2016146711A1
(en)
|
2015-03-16 |
2016-09-22 |
Dsm Ip Assets B.V. |
Udp-glycosyltransferases
|
WO2016153305A1
(ko)
*
|
2015-03-26 |
2016-09-29 |
한국생명공학연구원 |
표적 유전자 특이적 핵산 프로브 및 Fok Ι 제한효소 이량체를 이용하여 세포 내에서 표적 유전자를 특이적으로 편집하기 위한 조성물 및 이의 용도
|
CA2981509A1
(en)
*
|
2015-03-30 |
2016-10-06 |
The Board Of Regents Of The Nevada System Of Higher Educ. On Behalf Of The University Of Nevada, La |
Compositions comprising talens and methods of treating hiv
|
CA2981077A1
(en)
|
2015-04-03 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
WO2016176690A2
(en)
|
2015-04-30 |
2016-11-03 |
The Trustees Of Columbia University In The City Of New York |
Gene therapy for autosomal dominant diseases
|
US11845928B2
(en)
|
2015-05-04 |
2023-12-19 |
Tsinghua University |
Methods and kits for fragmenting DNA
|
EP3095870A1
(de)
|
2015-05-19 |
2016-11-23 |
Kws Saat Se |
Verfahren zur in-planta-transformation von pflanzen und darauf basierte herstellungsverfahren und daraus erhältliche produkte
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
ES2594486B1
(es)
|
2015-06-19 |
2017-09-26 |
Biopraxis Research Aie |
Molécula de ácido nucleico, proteína de fusión y método para modificar el material genético de una célula
|
US11193131B2
(en)
|
2015-06-30 |
2021-12-07 |
Regents Of The University Of Minnesota |
Haploid inducer line for accelerated genome editing
|
CN108026540A
(zh)
|
2015-07-17 |
2018-05-11 |
中国科学院遗传与发育生物学研究所 |
抗白粉病的小麦植物
|
JP2018524992A
(ja)
*
|
2015-07-23 |
2018-09-06 |
メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ |
ミトコンドリアdnaの編集
|
AU2016307066A1
(en)
|
2015-08-07 |
2018-02-08 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
WO2017031370A1
(en)
|
2015-08-18 |
2017-02-23 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
US10898522B2
(en)
|
2015-08-19 |
2021-01-26 |
Children's Research Institute, Children's National Medical Center |
Compositions and methods for treating graft versus host disease
|
JP6664693B2
(ja)
*
|
2015-09-09 |
2020-03-13 |
国立大学法人神戸大学 |
標的化したdna配列の核酸塩基を特異的に変換する、グラム陽性菌のゲノム配列の変換方法、及びそれに用いる分子複合体
|
US10837024B2
(en)
|
2015-09-17 |
2020-11-17 |
Cellectis |
Modifying messenger RNA stability in plant transformations
|
WO2017066497A2
(en)
|
2015-10-13 |
2017-04-20 |
Duke University |
Genome engineering with type i crispr systems in eukaryotic cells
|
EP3362074B1
(de)
|
2015-10-16 |
2023-08-09 |
President and Fellows of Harvard College |
Pd-1-modulation in regulatorischen t-zellen zur regulierung von t-zelleffektorimmunreaktionen
|
IL294014B2
(en)
|
2015-10-23 |
2024-07-01 |
Harvard College |
Nucleobase editors and their uses
|
EP3673732A3
(de)
|
2015-10-27 |
2020-07-29 |
Recombinetics, Inc. |
Engineering von humanisierten car t-zellen und -plättchen durch genetische ergänzung
|
WO2017075329A2
(en)
|
2015-10-29 |
2017-05-04 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids
|
ES2953925T3
(es)
|
2015-11-04 |
2023-11-17 |
Fate Therapeutics Inc |
Ingeniería genómica de células pluripotentes
|
EP3371301A4
(de)
|
2015-11-04 |
2019-06-26 |
Fate Therapeutics, Inc. |
Verfahren und zusammensetzungen zur induzierung der differenzierung hämatopoietischer zellen
|
WO2017079428A1
(en)
|
2015-11-04 |
2017-05-11 |
President And Fellows Of Harvard College |
Site specific germline modification
|
CA3005878A1
(en)
|
2015-11-19 |
2017-05-26 |
The Brigham And Women's Hospital, Inc. |
Lymphocyte antigen cd5-like (cd5l)-interleukin 12b (p40) heterodimers in immunity
|
DK3382019T3
(da)
|
2015-11-27 |
2022-05-30 |
Univ Kobe Nat Univ Corp |
Fremgangsmåde til omdannelse af enkimet plantegenomsekvens, hvori nukleinsyrebase i målrettet DNA-sekvens specifikt omdannes, og molekylært kompleks anvendt deri
|
EP3173485B1
(de)
|
2015-11-27 |
2021-08-25 |
KWS SAAT SE & Co. KGaA |
Kühletolerante pflanze
|
EP3389677B1
(de)
|
2015-12-18 |
2024-06-26 |
Sangamo Therapeutics, Inc. |
Gezielte zerstörung des t-zell-rezeptors
|
JP2018537112A
(ja)
|
2015-12-18 |
2018-12-20 |
サンガモ セラピューティクス, インコーポレイテッド |
Mhc細胞受容体の標的化破壊
|
US11840693B2
(en)
|
2015-12-21 |
2023-12-12 |
KWS SAAT SE & Co. KGaA |
Restorer plants
|
DE102015016445A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
DE102015017161A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
KR20180095719A
(ko)
|
2016-01-11 |
2018-08-27 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
키메라 단백질 및 면역요법 방법
|
IL260532B2
(en)
|
2016-01-11 |
2023-12-01 |
Univ Leland Stanford Junior |
Systems containing chaperone proteins and their uses for controlling gene expression
|
UY37108A
(es)
|
2016-02-02 |
2017-08-31 |
Cellectis |
Modificación de la composición de aceites de soja mediante el knockout dirigido de los genes fad3a/b/c
|
JP2019508037A
(ja)
|
2016-02-16 |
2019-03-28 |
イェール ユニバーシティーYale Universit |
標的化遺伝子編集を増強するための組成物およびその使用方法
|
WO2017143061A1
(en)
|
2016-02-16 |
2017-08-24 |
Yale University |
Compositions and methods for treatment of cystic fibrosis
|
US10973930B2
(en)
|
2016-02-18 |
2021-04-13 |
The Penn State Research Foundation |
Generating GABAergic neurons in brains
|
US20190249172A1
(en)
|
2016-02-18 |
2019-08-15 |
The Regents Of The University Of California |
Methods and compositions for gene editing in stem cells
|
CA3014871A1
(en)
|
2016-02-26 |
2017-08-31 |
Cellectis |
Micelle based system nuclease encapsulation for in-vivo gene editing
|
EP3429567B1
(de)
|
2016-03-16 |
2024-01-10 |
The J. David Gladstone Institutes |
Verfahren und zusammensetzungen zur behandlung von fettleibigkeit und/oder diabetes und zur identifizierung von behandlungskandidaten
|
US20210309965A1
(en)
|
2016-03-21 |
2021-10-07 |
Dana-Farber Cancer Institute, Inc. |
T-cell exhaustion state-specific gene expression regulators and uses thereof
|
CN109476716A
(zh)
|
2016-03-23 |
2019-03-15 |
加利福尼亚大学董事会 |
治疗线粒体障碍的方法
|
US20190117799A1
(en)
|
2016-04-01 |
2019-04-25 |
The Brigham And Women's Hospital, Inc. |
Stimuli-responsive nanoparticles for biomedical applications
|
WO2017180711A1
(en)
|
2016-04-13 |
2017-10-19 |
Editas Medicine, Inc. |
Grna fusion molecules, gene editing systems, and methods of use thereof
|
WO2017178632A1
(en)
|
2016-04-13 |
2017-10-19 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
CR20180503A
(es)
*
|
2016-04-14 |
2018-12-21 |
Hutchinson Fred Cancer Res |
Composiciones y métodos para programar células terapéuticas utilizando nanoportadores de ácidos nucleicos dirigidos
|
EP3429633B1
(de)
|
2016-04-15 |
2021-02-24 |
Cellectis |
Verfahren zur herstellung von wirkstoffspezifischen überempfindlichen t-zellen zur immuntherapie mittels geninaktivierung
|
CN107312788B
(zh)
*
|
2016-04-26 |
2020-07-28 |
中国科学院动物研究所 |
一种tale重复序列载体的构建方法
|
US10751423B2
(en)
|
2016-05-02 |
2020-08-25 |
Massachusetts Institute Of Technology |
Nanoparticle conjugates of highly potent toxins and intraperitoneal administration of nanoparticles for treating or imaging cancer
|
EP3458599A1
(de)
|
2016-05-16 |
2019-03-27 |
Evolva SA |
Herstellung von steviolglycosiden in rekombinanten wirten
|
US11293033B2
(en)
|
2016-05-18 |
2022-04-05 |
Amyris, Inc. |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
|
CN105950623B
(zh)
*
|
2016-05-19 |
2018-11-30 |
电子科技大学 |
一种用于talen高效构建的双rvd单元模块库及talen构建方法
|
EP3464333B1
(de)
|
2016-05-26 |
2024-05-08 |
Nunhems B.V. |
Pflanzen, die samenlose früchte produzieren
|
US10253316B2
(en)
|
2017-06-30 |
2019-04-09 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
US11293021B1
(en)
|
2016-06-23 |
2022-04-05 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
US11471462B2
(en)
|
2016-06-27 |
2022-10-18 |
The Broad Institute, Inc. |
Compositions and methods for detecting and treating diabetes
|
CN105949293B
(zh)
*
|
2016-06-28 |
2019-08-13 |
福建农林大学 |
植物源高效转录激活功能域sac3及应用
|
CA3029271A1
(en)
|
2016-06-28 |
2018-01-04 |
Cellectis |
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
|
CA3029761A1
(en)
|
2016-07-06 |
2018-01-11 |
Cellectis |
Sequential gene editing in primary immune cells
|
EP4321623A3
(de)
|
2016-07-15 |
2024-05-15 |
Salk Institute for Biological Studies |
Verfahren und zusammensetzungen zum genom-editieren von sich nichtteilenden zellen
|
AU2017302657A1
(en)
|
2016-07-29 |
2019-02-14 |
Regeneron Pharmaceuticals, Inc. |
Mice comprising mutations resulting in expression of c-truncated fibrillin-1
|
IL308426A
(en)
|
2016-08-03 |
2024-01-01 |
Harvard College |
Adenosine nuclear base editors and their uses
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
AU2017308121A1
(en)
|
2016-08-11 |
2019-03-07 |
The Jackson Laboratory |
Methods and compositions relating to improved human red blood cell survival in genetically modified immunodeficient non-human animals
|
EP3500666A4
(de)
|
2016-08-17 |
2020-04-08 |
Monsanto Technology LLC |
Verfahren und zusammensetzungen für kleinwüchsige pflanzen durch manipulation des gibberellin-metabolismus zur erhöhung des erntefähigen ertrags
|
CN116115629A
(zh)
|
2016-08-17 |
2023-05-16 |
菲克特生物科学股份有限公司 |
核酸产品及其施用方法
|
CA3034271A1
(en)
|
2016-08-18 |
2018-02-22 |
Cellectis |
Black-spot resistant potatoes with reduced tuber-specific polyphenol oxidase activity
|
KR20220145913A
(ko)
|
2016-08-24 |
2022-10-31 |
상가모 테라퓨틱스, 인코포레이티드 |
가공된 표적 특이적 뉴클레아제
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
EP3503927A1
(de)
|
2016-08-29 |
2019-07-03 |
The Regents of the University of California |
Topische formulierungen auf basis von ionischen spezies zur hautbehandlung
|
CA3035484A1
(en)
|
2016-09-01 |
2018-03-08 |
Cellectis |
Methods for altering amino acid content in plants
|
US10960085B2
(en)
|
2016-09-07 |
2021-03-30 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
CA3034643A1
(en)
|
2016-09-20 |
2018-03-29 |
Ellen Weisberg |
Compositions and methods for identification, assessment, prevention, and treatment of aml using usp10 biomarkers and modulators
|
WO2018057790A1
(en)
|
2016-09-21 |
2018-03-29 |
Recombinetics, Inc. |
Animal models for cardiomyopathy
|
US20190225974A1
(en)
|
2016-09-23 |
2019-07-25 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome optimization in plants
|
DK3523326T3
(da)
|
2016-10-04 |
2020-08-03 |
Prec Biosciences Inc |
Samstimulerende domæner til anvendelse i genetisk modificerede celler
|
WO2018069343A1
(en)
|
2016-10-10 |
2018-04-19 |
Limagrain Europe |
Nucleic acid encoding sm1 resistance to orange wheat blossom midge and method of use
|
WO2018069232A1
(en)
|
2016-10-10 |
2018-04-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of having cardiac hypertrophy
|
SG11201903089RA
(en)
|
2016-10-14 |
2019-05-30 |
Harvard College |
Aav delivery of nucleobase editors
|
GB201617559D0
(en)
|
2016-10-17 |
2016-11-30 |
University Court Of The University Of Edinburgh The |
Swine comprising modified cd163 and associated methods
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
US20190249183A1
(en)
|
2016-10-24 |
2019-08-15 |
Javier Gil Humanes |
Multiplex gene targeting in plants
|
WO2018076335A1
(en)
|
2016-10-31 |
2018-05-03 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Compositions and methods for enhancing abiotic stress tolerance
|
CN109906030B
(zh)
|
2016-11-04 |
2022-03-18 |
安健基因公司 |
用于产生仅重链抗体的经基因修饰的非人动物和方法
|
US11396669B2
(en)
|
2016-11-07 |
2022-07-26 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
WO2018092072A1
(en)
|
2016-11-16 |
2018-05-24 |
Cellectis |
Methods for altering amino acid content in plants through frameshift mutations
|
JP6948718B2
(ja)
|
2016-11-28 |
2021-10-13 |
国立大学法人大阪大学 |
ゲノム編集方法
|
WO2018112282A1
(en)
|
2016-12-14 |
2018-06-21 |
Ligandal, Inc. |
Compositions and methods for nucleic acid and/or protein payload delivery
|
US20200085758A1
(en)
|
2016-12-16 |
2020-03-19 |
The Brigham And Women's Hospital, Inc. |
Co-delivery of nucleic acids for simultaneous suppression and expression of target genes
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
WO2018123938A1
(ja)
*
|
2016-12-27 |
2018-07-05 |
国立研究開発法人農業・食品産業技術総合研究機構 |
ゲノム編集植物の作出方法
|
EP3565535A4
(de)
|
2017-01-05 |
2020-12-30 |
Fred Hutchinson Cancer Research Center |
Systeme und verfahren zur verbesserung der impfstoffwirksamkeit
|
GB201700380D0
(en)
|
2017-01-10 |
2017-02-22 |
Plant Bioscience Ltd |
Methods of increasing seed yield
|
KR102619197B1
(ko)
|
2017-01-23 |
2024-01-03 |
리제너론 파마슈티칼스 인코포레이티드 |
Hsd17b13 변종 및 이것의 용도
|
US20190367937A1
(en)
|
2017-02-09 |
2019-12-05 |
Fujian Agriculture And Forestry University |
Expression of a phosphate transporter for improving plant yield
|
CA3054031A1
(en)
|
2017-02-22 |
2018-08-30 |
Crispr Therapeutics Ag |
Compositions and methods for gene editing
|
EP3366778A1
(de)
|
2017-02-28 |
2018-08-29 |
Kws Saat Se |
Haploidisierung in sorghum
|
US11307139B2
(en)
|
2017-03-03 |
2022-04-19 |
Pioneer Hi-Bred International, Inc. |
Non-destructive assay for soybean seeds using near infrared analysis
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
EP3592777A1
(de)
|
2017-03-10 |
2020-01-15 |
President and Fellows of Harvard College |
Cytosin-zu-guanin-baseneditor
|
JP2020515248A
(ja)
|
2017-03-21 |
2020-05-28 |
ザ ジャクソン ラボラトリーThe Jackson Laboratory |
ヒトAPOE4およびマウスTrem2 p.R47Hを発現する遺伝子改変されたマウス、ならびにその使用の方法
|
JP7133856B2
(ja)
|
2017-03-22 |
2022-09-09 |
国立大学法人神戸大学 |
細胞内在性のdna修飾酵素を利用して標的化したdnaの核酸塩基を特異的に変換する、細胞の核酸配列の変換方法、及びそれに用いる分子複合体
|
JP7191388B2
(ja)
|
2017-03-23 |
2022-12-19 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
核酸によってプログラム可能なdna結合蛋白質を含む核酸塩基編集因子
|
EA201992261A1
(ru)
|
2017-03-24 |
2020-03-10 |
Инститьют Оф Джинетикс Энд Дивелопментал Байолоджи Чайниз Академи Оф Сайенсиз |
Способы повышения урожая зерна
|
US10980779B2
(en)
|
2017-03-24 |
2021-04-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
GFI1 inhibitors for the treatment of hyperglycemia
|
WO2018181863A1
(ja)
|
2017-03-30 |
2018-10-04 |
国立大学法人東京大学 |
異なる複数の目的遺伝子の評価方法
|
WO2018183908A1
(en)
|
2017-03-31 |
2018-10-04 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
WO2018187493A1
(en)
|
2017-04-04 |
2018-10-11 |
Yale University |
Compositions and methods for in utero delivery
|
US20210115407A1
(en)
|
2017-04-12 |
2021-04-22 |
The Broad Institute, Inc. |
Respiratory and sweat gland ionocytes
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
EP3392339A1
(de)
|
2017-04-18 |
2018-10-24 |
Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen |
Verbesserte genomeditierung in pflanzenzellen
|
US12058986B2
(en)
|
2017-04-20 |
2024-08-13 |
Egenesis, Inc. |
Method for generating a genetically modified pig with inactivated porcine endogenous retrovirus (PERV) elements
|
EP3612232A1
(de)
|
2017-04-21 |
2020-02-26 |
The Broad Institute, Inc. |
Gezielte abgabe an beta-zellen
|
ES2977620T3
(es)
|
2017-04-25 |
2024-08-27 |
Cellectis |
Alfalfa con composición reducida de lignina
|
IL301115A
(en)
|
2017-04-28 |
2023-05-01 |
Acuitas Therapeutics Inc |
New lipid carbonyl and lipid nanoparticle formulations for delivery of nucleic acids
|
WO2018204469A2
(en)
|
2017-05-03 |
2018-11-08 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
WO2018204777A2
(en)
|
2017-05-05 |
2018-11-08 |
The Broad Institute, Inc. |
Methods for identification and modification of lncrna associated with target genotypes and phenotypes
|
AU2018266698A1
(en)
|
2017-05-08 |
2019-11-28 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
EP3621433B1
(de)
|
2017-05-12 |
2022-07-27 |
The Jackson Laboratory |
Nsg mause ohne mhc klasse i und klasse ii
|
WO2018211032A1
(en)
|
2017-05-17 |
2018-11-22 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
MX2019014068A
(es)
|
2017-05-25 |
2020-08-03 |
Inst Genetics & Developmental Biology Cas |
Metodos para incrementar la productividad del grano.
|
EP3409104A1
(de)
|
2017-05-31 |
2018-12-05 |
Vilmorin et Cie |
Tomatenpflanze, die gegen tomatengelbblattkräuselvirus, pulverförmigen mehltau und nematoden beständig ist
|
WO2020249996A1
(en)
|
2019-06-14 |
2020-12-17 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus
|
EP3409106A1
(de)
|
2017-06-01 |
2018-12-05 |
Vilmorin et Cie |
Toleranz in pflanzen von solanum lycopersicum gegenüber dem tobamovirus tomato brown rugose fruit virus (tbrfv)
|
US11879128B2
(en)
|
2017-06-05 |
2024-01-23 |
Consejo Superior De Investigaciones Científicas (Csic)—Delegación Andalucía |
Targeting of gluten by genome editing
|
CA3065938A1
(en)
|
2017-06-05 |
2018-12-13 |
Regeneron Pharmaceuticals, Inc. |
B4galt1 variants and uses thereof
|
US11820822B2
(en)
|
2017-06-06 |
2023-11-21 |
Dana-Farber Cancer Institute, Inc. |
Methods for sensitizing cancer cells to T cell-mediated killing by modulating molecular pathways
|
WO2018231999A1
(en)
|
2017-06-13 |
2018-12-20 |
Regents Of The University Of Minnesota |
Materials and methods for increasing gene editing frequency
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
MX2019015188A
(es)
|
2017-06-15 |
2020-08-03 |
Univ California |
Inserciones de adn no virales orientadas.
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
US20210139870A1
(en)
|
2017-06-19 |
2021-05-13 |
Cellectis |
Anti-hbv combination therapies involving specific endonucleases
|
WO2018234370A1
(en)
|
2017-06-20 |
2018-12-27 |
Institut Curie |
DEFECTIVE IMMUNE CELLS AGAINST SUV39H1
|
IL271516B2
(en)
|
2017-06-23 |
2024-10-01 |
Univ Of Kentucky Research Foundation |
A method for modulating the alkaloid content of a plant, a method for producing a plant and a modified plant
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
CA3064601A1
(en)
|
2017-06-26 |
2019-01-03 |
The Broad Institute, Inc. |
Crispr/cas-adenine deaminase based compositions, systems, and methods for targeted nucleic acid editing
|
JP2020529834A
(ja)
|
2017-06-30 |
2020-10-15 |
プレシジョン バイオサイエンシズ,インク. |
T細胞受容体アルファ遺伝子の改変されたイントロンを含む遺伝子改変t細胞
|
US20200208146A1
(en)
|
2017-07-12 |
2020-07-02 |
Mayo Foundation For Medical Education And Research |
Materials and methods for efficient targeted knock in or gene replacement
|
WO2019014581A1
(en)
|
2017-07-14 |
2019-01-17 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR MODULATING THE ACTIVITY OF A CYTOTOXIC LYMPHOCYTE
|
US12105089B2
(en)
|
2017-07-17 |
2024-10-01 |
The Broad Institute, Inc. |
Cell atlas of the healthy and ulcerative colitis human colon
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
EP3663310A4
(de)
|
2017-08-04 |
2021-08-11 |
Peking University |
Tale-rvd mit spezifischer erkennung einer durch methylierung modifizierten dna-base und anwendung davon
|
US20190045761A1
(en)
|
2017-08-11 |
2019-02-14 |
Recombinetics, Inc. |
Inducible disease models methods of making them and use in tissue complementation
|
EP3447134B1
(de)
|
2017-08-22 |
2023-10-11 |
KWS SAAT SE & Co. KGaA |
Erhöhte pilzresistenz bei nutzpflanzen
|
US20210054404A1
(en)
|
2017-08-22 |
2021-02-25 |
Napigen, Inc. |
Organelle genome modification using polynucleotide guided endonuclease
|
WO2019038417A1
(en)
|
2017-08-25 |
2019-02-28 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
METHODS FOR INCREASING GRAIN YIELD
|
US10738327B2
(en)
|
2017-08-28 |
2020-08-11 |
Inscripta, Inc. |
Electroporation cuvettes for automation
|
AU2018325363A1
(en)
|
2017-08-29 |
2020-04-09 |
Global Crop Innovations Pty. Ltd. |
Improved BLue Aleurone and other segregation systems
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
WO2019190590A2
(en)
|
2017-09-18 |
2019-10-03 |
Amyris, Inc. |
Methods for genomic integration for kluyveromyces host cells
|
US11884928B2
(en)
|
2017-09-18 |
2024-01-30 |
Amyris, Inc. |
Methods for genetic engineering Kluyveromyces host cells
|
WO2019060759A1
(en)
|
2017-09-21 |
2019-03-28 |
Dana-Farber Cancer Institute, Inc. |
ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF PLANT EXTRACTS JUSTICIA
|
BR112020003609A2
(pt)
|
2017-09-29 |
2020-09-01 |
Regeneron Pharmaceuticals, Inc. |
sistema e método para formar uma emulsão
|
US10435713B2
(en)
|
2017-09-30 |
2019-10-08 |
Inscripta, Inc. |
Flow through electroporation instrumentation
|
WO2019070856A1
(en)
|
2017-10-03 |
2019-04-11 |
Precision Biosciences, Inc. |
MODIFIED EPIDERMAL GROWTH FACTOR RECEPTOR PEPTIDES FOR USE IN GENETICALLY MODIFIED CELLS
|
WO2019071054A1
(en)
|
2017-10-04 |
2019-04-11 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF BUCKLES AND / OR CHROMATIN DOMAINS
|
WO2019075360A1
(en)
|
2017-10-13 |
2019-04-18 |
Selecta Biosciences, Inc. |
METHODS AND COMPOSITIONS FOR MITIGATING ANTI-VECTOR VIRAL TRANSFER IGM RESPONSES
|
CN111757937A
(zh)
|
2017-10-16 |
2020-10-09 |
布罗德研究所股份有限公司 |
腺苷碱基编辑器的用途
|
EP3684919A1
(de)
|
2017-10-19 |
2020-07-29 |
Cellectis |
Gezielte genintegration von nk-inhibitor-genen für eine verbesserte immunzellentherapie
|
IL274179B2
(en)
|
2017-10-27 |
2024-02-01 |
Univ California |
Targeted replacement of endogenous T cell receptors
|
AR114025A1
(es)
|
2017-10-31 |
2020-07-15 |
Limagrain Europe |
Trigo que comprende alelos restauradores de la fertilidad masculina
|
EP3704238B1
(de)
|
2017-11-01 |
2024-01-03 |
Precision Biosciences, Inc. |
Gegen humane und canine faktor-viii-gene gerichtete manipulierte nukleasen als behandlung für hämophilie a
|
EP3710039A4
(de)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
Verfahren und zusammensetzungen zur behandlung von krebs durch targeting des clec2d-klrb1-wegs
|
EP3713644B1
(de)
|
2017-11-20 |
2024-08-07 |
University of Georgia Research Foundation, Inc. |
Zusammensetzungen und verfahren zur modulation von hif-2a zur verbesserung der muskelbildung und -reparatur
|
WO2019106163A1
(en)
|
2017-12-01 |
2019-06-06 |
Cellectis |
Reprogramming of genetically engineered primary immune cells
|
WO2019118893A1
(en)
|
2017-12-15 |
2019-06-20 |
Dana-Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
US20210087537A1
(en)
|
2017-12-22 |
2021-03-25 |
Fate Therapeutics, Inc. |
Enhanced immune effector cells and use thereof
|
DK3501268T3
(da)
|
2017-12-22 |
2021-11-08 |
Kws Saat Se & Co Kgaa |
Regenerering af planter i tilstedeværelse af histondeacetylase hæmmere
|
CN107868123B
(zh)
|
2017-12-25 |
2020-05-12 |
中国农业科学院作物科学研究所 |
一种同时提高植物产量和抗性的基因及其应用
|
EP3508581A1
(de)
|
2018-01-03 |
2019-07-10 |
Kws Saat Se |
Regenerierung von genetisch modifizierten pflanzen
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
CN111566121A
(zh)
|
2018-01-12 |
2020-08-21 |
巴斯夫欧洲公司 |
小麦7a染色体上决定每穗小穗数QTL的基因
|
WO2019158911A1
(en)
|
2018-02-14 |
2019-08-22 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Methods of increasing nutrient use efficiency
|
EP3752618A4
(de)
|
2018-02-15 |
2021-11-03 |
Monsanto Technology LLC |
Zusammensetzungen und verfahren zur verbesserung des ernteertrages durch trait-stacking
|
AU2019225251A1
(en)
|
2018-02-26 |
2020-10-15 |
AnTolRx, Inc. |
Tolerogenic liposomes and methods of use thereof
|
WO2019183630A2
(en)
|
2018-03-23 |
2019-09-26 |
The Trustees Of Columbia University In The City Of New York |
Gene editing for autosomal dominant diseases
|
SG11202009319YA
(en)
|
2018-03-26 |
2020-10-29 |
Univ Kobe Nat Univ Corp |
Method for modifying target site in double-stranded dna in cell
|
EP3545756A1
(de)
|
2018-03-28 |
2019-10-02 |
KWS SAAT SE & Co. KGaA |
Regeneration von pflanzen in gegenwart von inhibitoren der histonmethyltransferase ezh2
|
CA3094473A1
(en)
|
2018-03-29 |
2019-10-03 |
Cellectis |
Tale-nucleases for allele-specific codon modification
|
AU2019241967A1
(en)
|
2018-03-29 |
2020-11-19 |
Inscripta, Inc. |
Automated control of cell growth rates for induction and transformation
|
AU2019243315A1
(en)
|
2018-03-29 |
2020-09-24 |
Fate Therapeutics, Inc. |
Engineered immune effector cells and use thereof
|
KR20200141470A
(ko)
|
2018-04-06 |
2020-12-18 |
칠드런'즈 메디컬 센터 코포레이션 |
체세포 재프로그래밍 및 각인의 조정을 위한 조성물 및 방법
|
GB201805865D0
(en)
|
2018-04-09 |
2018-05-23 |
Innes John Centre |
Genes
|
WO2019200004A1
(en)
|
2018-04-13 |
2019-10-17 |
Inscripta, Inc. |
Automated cell processing instruments comprising reagent cartridges
|
US11981892B2
(en)
|
2018-04-16 |
2024-05-14 |
University Of Massachusetts |
Compositions and methods for improved gene editing
|
US10858761B2
(en)
|
2018-04-24 |
2020-12-08 |
Inscripta, Inc. |
Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
|
US10508273B2
(en)
|
2018-04-24 |
2019-12-17 |
Inscripta, Inc. |
Methods for identifying selective binding pairs
|
SI3560330T1
(sl)
|
2018-04-24 |
2022-08-31 |
KWS SAAT SE & Co. KGaA |
Rastline z izboljšano prebavljivostjo in markerskimi haplotipi
|
US10557216B2
(en)
|
2018-04-24 |
2020-02-11 |
Inscripta, Inc. |
Automated instrumentation for production of T-cell receptor peptide libraries
|
TWI686477B
(zh)
*
|
2018-04-25 |
2020-03-01 |
國立成功大學 |
特異性造成植物葉綠體基因變異的轉殖載體、套組、方法及利用其產生之轉殖植物細胞與農桿菌
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
US20210147831A1
(en)
|
2018-04-27 |
2021-05-20 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
CA3234120A1
(en)
|
2018-05-02 |
2019-11-07 |
Cellectis |
Engineering wheat with increased dietary fiber
|
WO2019213660A2
(en)
|
2018-05-04 |
2019-11-07 |
The Broad Institute, Inc. |
Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
|
EP3567111A1
(de)
|
2018-05-09 |
2019-11-13 |
KWS SAAT SE & Co. KGaA |
Gen für resistenz gegen ein pathogen der gattung heterodera
|
CA3099364A1
(en)
|
2018-05-11 |
2019-11-14 |
Crispr Therapeutics Ag |
Methods and compositions for treating cancer comprising engineered t cells comprising modified chimeric antigen receptors
|
GB201808424D0
(en)
|
2018-05-23 |
2018-07-11 |
Lucite Int Uk Ltd |
Methods for producing BMA and MMA using genetically modified microorganisms
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
GB201809273D0
(en)
|
2018-06-06 |
2018-07-25 |
Vib Vzw |
Novel mutant plant cinnamoyl-coa reductase proteins
|
CN112384063A
(zh)
|
2018-06-07 |
2021-02-19 |
以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 |
再生及转殖大麻的方法
|
WO2019236943A2
(en)
|
2018-06-07 |
2019-12-12 |
The Brigham And Women's Hospital, Inc. |
Methods for generating hematopoietic stem cells
|
US11827892B2
(en)
|
2018-06-07 |
2023-11-28 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) |
Nucleic acid constructs and methods of using same
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
EP3806619A1
(de)
|
2018-06-15 |
2021-04-21 |
Nunhems B.V. |
Kernlose wassermelonenpflanzen mit modifikationen in einem abc-transporter-gen
|
CA3103564A1
(en)
|
2018-06-15 |
2019-12-19 |
KWS SAAT SE & Co. KGaA |
Methods for enhancing genome engineering efficiency
|
CN112585269A
(zh)
|
2018-06-15 |
2021-03-30 |
科沃施种子欧洲股份两合公司 |
改善植物中基因组工程化和再生的方法ii
|
BR112020025349A2
(pt)
|
2018-06-15 |
2021-03-09 |
KWS SAAT SE & Co. KGaA |
Métodos para melhorar a engenharia e regeneração do genoma em planta
|
EP3809838A4
(de)
|
2018-06-21 |
2022-03-23 |
The Jackson Laboratory |
Genetisch modifizierte mausmodelle der alzheimer-krankheit
|
WO2020006112A1
(en)
*
|
2018-06-26 |
2020-01-02 |
Regents Of The University Of Minnesota |
Delivery of developmental regulators to plants for the induction of meristematic tissue with genetic alterations
|
US20210324398A1
(en)
|
2018-06-29 |
2021-10-21 |
Pioneer Hi-Bred International, Inc. |
Edited nac genes in plants
|
CA3108767A1
(en)
|
2018-06-30 |
2020-01-02 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
WO2020012365A1
(en)
|
2018-07-09 |
2020-01-16 |
Cellectis |
Canola with high oleic acid
|
US20210310039A1
(en)
|
2018-07-31 |
2021-10-07 |
The University Of Tokyo |
Membrane protein activity measurement method
|
US11939593B2
(en)
|
2018-08-01 |
2024-03-26 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for improving embryo development
|
GB201812603D0
(en)
|
2018-08-02 |
2018-09-19 |
British American Tobacco Investments Ltd |
Method
|
KR20210040985A
(ko)
|
2018-08-07 |
2021-04-14 |
가부시키가이샤 모달리스 |
신규 전사 액티베이터
|
EP3607819A1
(de)
|
2018-08-10 |
2020-02-12 |
Vilmorin et Cie |
Resistenz gegen xanthomonas campestris pv. campestris (xcc) in blumenkohl
|
US10532324B1
(en)
|
2018-08-14 |
2020-01-14 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
US11142740B2
(en)
|
2018-08-14 |
2021-10-12 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
US20210317429A1
(en)
|
2018-08-20 |
2021-10-14 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
AU2019326408A1
(en)
|
2018-08-23 |
2021-03-11 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
CA3108922A1
(en)
|
2018-08-29 |
2020-03-05 |
Amyris, Inc. |
Cells and methods for selection based assay
|
CN109706155B
(zh)
*
|
2018-08-30 |
2022-04-19 |
南京农业大学 |
pOsHEN1::OsSPL14基因表达盒及其构建方法和应用
|
WO2020081149A2
(en)
|
2018-08-30 |
2020-04-23 |
Inscripta, Inc. |
Improved detection of nuclease edited sequences in automated modules and instruments
|
US20210338815A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods for enhancing triplex and nuclease-based gene editing
|
EP3623379A1
(de)
|
2018-09-11 |
2020-03-18 |
KWS SAAT SE & Co. KGaA |
Gen zur modifizierung von rhizomania-virus (bnyvv)-resistenz
|
EP3849565A4
(de)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
Verminderung der cd33-expression zum selektiven schutz von therapeutischen zellen
|
EP3853244A4
(de)
|
2018-09-18 |
2022-09-14 |
Sangamo Therapeutics, Inc. |
Für programmierten zelltod 1 (pd1) spezifische nukleasen
|
CA3113095A1
(en)
|
2018-09-18 |
2020-03-26 |
Vnv Newco Inc. |
Arc-based capsids and uses thereof
|
CN113015801A
(zh)
*
|
2018-09-20 |
2021-06-22 |
赛诺菲 |
基于内含子的通用克隆方法和组合物
|
GB201815672D0
(en)
|
2018-09-26 |
2018-11-07 |
Innes John Centre |
Methods for altering starch granule size profile
|
WO2020071528A1
(ja)
|
2018-10-04 |
2020-04-09 |
株式会社カネカ |
植物のゲノム編集に用いられるdna構築物
|
WO2020077236A1
(en)
|
2018-10-12 |
2020-04-16 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
EP3867375A1
(de)
|
2018-10-15 |
2021-08-25 |
Fondazione Telethon |
Genomeditierungsverfahren und konstrukte
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
BR112021007306A2
(pt)
|
2018-10-16 |
2021-07-27 |
Pioneer Hi-Bred International, Inc. |
mapeamento fino por edição genômica e identificação de gene causal
|
US11214781B2
(en)
|
2018-10-22 |
2022-01-04 |
Inscripta, Inc. |
Engineered enzyme
|
CA3116334A1
(en)
|
2018-10-22 |
2020-04-30 |
University Of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas9 fusion protein
|
EP3870697A4
(de)
|
2018-10-22 |
2022-11-09 |
Inscripta, Inc. |
Gentechnisch veränderte enzyme
|
AU2019370485A1
(en)
|
2018-11-02 |
2021-05-13 |
Annexon, Inc. |
Compositions and methods for treating brain injury
|
GB201817971D0
(en)
|
2018-11-02 |
2018-12-19 |
British American Tobacco Investments Ltd |
Method
|
EA202191257A1
(ru)
|
2018-11-07 |
2021-12-06 |
Криспр Терапьютикс Аг |
Противораковая терапия на основе иммуноцитов, связывающих liv1
|
MX2021005398A
(es)
|
2018-11-07 |
2021-07-06 |
Crispr Therapeutics Ag |
Terapia del cancer con celulas inmunitarias anti-cd33.
|
AU2019374523A1
(en)
|
2018-11-07 |
2021-05-20 |
Crispr Therapeutics Ag |
Anti-PTK7 immune cell cancer therapy
|
GB201818715D0
(en)
|
2018-11-16 |
2019-01-02 |
British American Tobacco Investments Ltd |
Method
|
CN113366009A
(zh)
|
2018-11-27 |
2021-09-07 |
科纳科学有限责任公司 |
用于生物合成大麻素的双向多酶支架
|
WO2020112195A1
(en)
|
2018-11-30 |
2020-06-04 |
Yale University |
Compositions, technologies and methods of using plerixafor to enhance gene editing
|
WO2020118073A1
(en)
|
2018-12-05 |
2020-06-11 |
Vertex Pharmaceuticals Incorporated |
Gene-editing systems for editing a cystic fibrosis transmembrane regulator (cftr) gene
|
KR20200071198A
(ko)
|
2018-12-10 |
2020-06-19 |
네오이뮨텍, 인코퍼레이티드 |
Nrf2 발현 조절 기반 T 세포 항암면역치료법
|
GB201820109D0
(en)
|
2018-12-11 |
2019-01-23 |
Vib Vzw |
Plants with a lignin trait and udp-glycosyltransferase mutation
|
CA3124110A1
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Crispr-associated transposase systems and methods of use thereof
|
CA3120799A1
(en)
|
2018-12-20 |
2020-06-25 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated repeat expansion
|
US20220090047A1
(en)
|
2018-12-21 |
2022-03-24 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
JP7523449B2
(ja)
|
2019-01-11 |
2024-07-26 |
アクイタス セラピューティクス インコーポレイテッド |
活性剤の脂質ナノ粒子送達のための脂質
|
MX2021008494A
(es)
|
2019-01-15 |
2021-08-19 |
Seminis Vegetable Seeds Inc |
Plantas de frijol verde con mejorada resistencia a enfermedades.
|
GB201900940D0
(en)
|
2019-01-23 |
2019-03-13 |
British American Tobacco Investments Ltd |
Method
|
WO2020157573A1
(en)
|
2019-01-29 |
2020-08-06 |
The University Of Warwick |
Methods for enhancing genome engineering efficiency
|
WO2020161261A1
(en)
|
2019-02-06 |
2020-08-13 |
Vilmorin & Cie |
New gene responsible for cytoplasmic male sterility
|
WO2020172343A2
(en)
|
2019-02-19 |
2020-08-27 |
Massachusetts Institute Of Technology |
Methods for treating injuries
|
WO2020178193A1
(en)
|
2019-03-01 |
2020-09-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method of treatment of sarcoidosis
|
SG11202109550TA
(en)
|
2019-03-07 |
2021-09-29 |
Univ Columbia |
Rna-guided dna integration using tn7-like transposons
|
EP3708651A1
(de)
|
2019-03-12 |
2020-09-16 |
KWS SAAT SE & Co. KGaA |
Verbesserung der pflanzenregeneration
|
US20220152115A1
(en)
|
2019-03-13 |
2022-05-19 |
The Broad Institute, Inc. |
Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof
|
WO2020191243A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
US11001831B2
(en)
|
2019-03-25 |
2021-05-11 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
AU2020247900A1
(en)
|
2019-03-25 |
2021-11-04 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
EP3947682B1
(de)
|
2019-04-03 |
2023-10-11 |
Precision Biosciences, Inc. |
Genetisch modifizierte immunzellen mit einer mikrorna-adaptierten shrna (shrnamir)
|
WO2020206162A1
(en)
|
2019-04-03 |
2020-10-08 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for insertion of antibody coding sequences into a safe harbor locus
|
CA3133359C
(en)
|
2019-04-04 |
2023-04-11 |
Regeneron Pharmaceuticals, Inc. |
Methods for scarless introduction of targeted modifications into targeting vectors
|
SG11202108454RA
(en)
|
2019-04-04 |
2021-09-29 |
Regeneron Pharma |
Non-human animals comprising a humanized coagulation factor 12 locus
|
EP3947646A1
(de)
|
2019-04-05 |
2022-02-09 |
Precision BioSciences, Inc. |
Verfahren zur herstellung von populationen genetisch modifizierter immunzellen
|
US20220186263A1
(en)
|
2019-04-05 |
2022-06-16 |
Osaka University |
Method for producing knock-in cell
|
EP3969607A1
(de)
|
2019-05-13 |
2022-03-23 |
KWS SAAT SE & Co. KGaA |
Trockenheitstoleranz bei mais
|
GB201906768D0
(en)
|
2019-05-14 |
2019-06-26 |
British American Tobacco Investments Ltd |
Method
|
CN113924367B
(zh)
|
2019-05-23 |
2024-07-23 |
南京农业大学 |
提高水稻籽粒产量的方法
|
AR118995A1
(es)
|
2019-05-25 |
2021-11-17 |
Kws Saat Se & Co Kgaa |
Mejorador de la inducción de haploides
|
CA3141863A1
(en)
|
2019-05-28 |
2020-12-03 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuated anti-viral transfer vector immune response
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
WO2020243661A1
(en)
|
2019-05-31 |
2020-12-03 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
JP2022534867A
(ja)
|
2019-06-04 |
2022-08-04 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ベータスリップ変異を有するヒト化ttr遺伝子座を含む非ヒト動物と使用方法
|
WO2020244759A1
(en)
|
2019-06-05 |
2020-12-10 |
Klemm & Sohn Gmbh & Co. Kg |
New plants having a white foliage phenotype
|
AU2020288623A1
(en)
|
2019-06-06 |
2022-01-06 |
Inscripta, Inc. |
Curing for recursive nucleic acid-guided cell editing
|
CN113939595A
(zh)
|
2019-06-07 |
2022-01-14 |
瑞泽恩制药公司 |
包括人源化白蛋白基因座的非人动物
|
WO2020252340A1
(en)
|
2019-06-14 |
2020-12-17 |
Regeneron Pharmaceuticals, Inc. |
Models of tauopathy
|
EP3987024A4
(de)
|
2019-06-20 |
2023-11-01 |
University Of Massachusetts |
Zusammensetzungen und verfahren zur verbesserten geneditierung
|
WO2020254850A1
(en)
|
2019-06-21 |
2020-12-24 |
Vilmorin & Cie |
Improvement of quality and permanence of green color of peppers at maturity and over-maturity
|
EP3986909A4
(de)
|
2019-06-21 |
2023-08-02 |
Inscripta, Inc. |
Genomweite rationell gestaltete mutationen, die zu einer erhöhten lysinproduktion in e. coli führen
|
US10927385B2
(en)
|
2019-06-25 |
2021-02-23 |
Inscripta, Inc. |
Increased nucleic-acid guided cell editing in yeast
|
WO2020261219A1
(en)
|
2019-06-27 |
2020-12-30 |
Crispr Therapeutics Ag |
Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer
|
EP3757219A1
(de)
|
2019-06-28 |
2020-12-30 |
KWS SAAT SE & Co. KGaA |
Verbesserte pflanzenregeneration und -umwandlung unter verwendung des grf1-booster-gens
|
GB201909562D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
GB201909563D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
EP3993612A1
(de)
|
2019-07-05 |
2022-05-11 |
Limagrain Europe |
Verfahren zur erhöhung des pflanzenertrags
|
EP3997111A4
(de)
|
2019-07-11 |
2023-07-26 |
The Regents Of The University Of California |
Verfahren zur verbesserten regeneration transgener pflanzen mit wachstumsregulierendem faktor (grf), grf-interaktionsfaktor (gif) oder chimären grf-gif-genen und proteinen
|
AU2020318781A1
(en)
|
2019-07-23 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immune cells defective for SUV39H1
|
FR3099178A1
(fr)
|
2019-07-24 |
2021-01-29 |
Soltis |
Tournesol à teneur élevée en acide oléique et procédé d’obtention
|
EP4004216A1
(de)
|
2019-07-25 |
2022-06-01 |
Precision BioSciences, Inc. |
Zusammensetzungen und verfahren zum sequenziellen stapeln von nukleinsäuresequenzen in einen genomischen locus
|
US10501404B1
(en)
|
2019-07-30 |
2019-12-10 |
Factor Bioscience Inc. |
Cationic lipids and transfection methods
|
WO2021019272A1
(en)
|
2019-07-31 |
2021-02-04 |
Vilmorin & Cie |
Tolerance to tolcndv in cucumber
|
EP3772542A1
(de)
|
2019-08-07 |
2021-02-10 |
KWS SAAT SE & Co. KGaA |
Modifzierung der genetischen variation bei nutzpflanzen durch modulation des pachytän-checkpointproteins 2
|
WO2021035054A1
(en)
|
2019-08-20 |
2021-02-25 |
Precision Biosciences, Inc. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
AU2020336992A1
(en)
|
2019-08-30 |
2022-04-14 |
Yale University |
Compositions and methods for delivery of nucleic acids to cells
|
US20220298501A1
(en)
|
2019-08-30 |
2022-09-22 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
EP4025689A1
(de)
|
2019-09-06 |
2022-07-13 |
CRISPR Therapeutics AG |
Genetisch veränderte t-zellen mit verbesserter haltbarkeit in kultur
|
CN114391040A
(zh)
|
2019-09-23 |
2022-04-22 |
欧米茄治疗公司 |
用于调节载脂蛋白b(apob)基因表达的组合物和方法
|
US11987791B2
(en)
|
2019-09-23 |
2024-05-21 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating hepatocyte nuclear factor 4-alpha (HNF4α) gene expression
|
US11542513B2
(en)
|
2019-09-26 |
2023-01-03 |
Seminis Vegetable Seeds, Inc. |
Lettuce plants having resistance to Nasonovia ribisnigri biotype Nr:1
|
GB201914137D0
(en)
|
2019-10-01 |
2019-11-13 |
Univ Leeds Innovations Ltd |
Modified Plants
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
CN114846022A
(zh)
|
2019-10-17 |
2022-08-02 |
科沃施种子欧洲股份两合公司 |
通过阻抑基因的下调增强作物的疾病抗性
|
EP3808170A1
(de)
|
2019-10-17 |
2021-04-21 |
Bejo Zaden B.V. |
Lactuca-sativa-resistenz gegen bremia lactucae
|
US20220411479A1
(en)
|
2019-10-30 |
2022-12-29 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
CN112779266A
(zh)
|
2019-11-06 |
2021-05-11 |
青岛清原化合物有限公司 |
在生物体内创制新基因的方法及应用
|
CN114746125A
(zh)
|
2019-11-08 |
2022-07-12 |
瑞泽恩制药公司 |
用于x连锁青少年型视网膜劈裂症疗法的crispr和aav策略
|
WO2021093943A1
(en)
|
2019-11-12 |
2021-05-20 |
KWS SAAT SE & Co. KGaA |
Gene for resistance to a pathogen of the genus heterodera
|
WO2021094805A1
(en)
|
2019-11-14 |
2021-05-20 |
Vilmorin & Cie |
Resistance to acidovorax valerianellae in corn salad
|
JP7448120B2
(ja)
|
2019-11-14 |
2024-03-12 |
国立研究開発法人農業・食品産業技術総合研究機構 |
プラズマを用いてゲノム編集酵素を植物細胞内に導入する方法
|
CN114901812A
(zh)
|
2019-11-14 |
2022-08-12 |
国立大学法人广岛大学 |
使用环状dna将抗原特异性受体基因导入至t细胞基因组的方法
|
WO2021102059A1
(en)
|
2019-11-19 |
2021-05-27 |
Inscripta, Inc. |
Methods for increasing observed editing in bacteria
|
WO2021108363A1
(en)
|
2019-11-25 |
2021-06-03 |
Regeneron Pharmaceuticals, Inc. |
Crispr/cas-mediated upregulation of humanized ttr allele
|
JP2023505039A
(ja)
|
2019-11-27 |
2023-02-08 |
カリックス インコーポレイテッド |
遺伝子編集のためのtalエフェクターヌクレアーゼ
|
CA3160096A1
(en)
|
2019-12-06 |
2021-06-10 |
Bruce J. Mccreedy Jr. |
Methods for cancer immunotherapy
|
EP4069837A4
(de)
|
2019-12-10 |
2024-03-13 |
Inscripta, Inc. |
Neue mad-nukleasen
|
EP3835309A1
(de)
|
2019-12-13 |
2021-06-16 |
KWS SAAT SE & Co. KGaA |
Verfahren zur erhöhung der kälte- oder frosttoleranz in einer pflanze
|
US10704033B1
(en)
|
2019-12-13 |
2020-07-07 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
WO2021117874A1
(ja)
|
2019-12-13 |
2021-06-17 |
中外製薬株式会社 |
細胞外プリン受容体リガンドを検出するシステムおよび当該システムを導入した非ヒト動物
|
CN113061626B
(zh)
*
|
2019-12-16 |
2024-01-19 |
中国科学院脑科学与智能技术卓越创新中心 |
一种组织特异性敲除斑马鱼基因的方法及应用
|
US11008557B1
(en)
|
2019-12-18 |
2021-05-18 |
Inscripta, Inc. |
Cascade/dCas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
|
GB201918902D0
(en)
|
2019-12-19 |
2020-02-05 |
Genome Res Ltd |
Cell differentiation
|
US10689669B1
(en)
|
2020-01-11 |
2020-06-23 |
Inscripta, Inc. |
Automated multi-module cell processing methods, instruments, and systems
|
CA3157061A1
(en)
|
2020-01-27 |
2021-08-05 |
Christian SILTANEN |
Electroporation modules and instrumentation
|
CN115135144A
(zh)
|
2020-01-31 |
2022-09-30 |
卡里克特公司 |
大豆中饱和脂肪的增加
|
EP4100525A1
(de)
|
2020-02-05 |
2022-12-14 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Verfahren zur behandlung von krebserkrankungen durch targeting eines epigenetischen faktors
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
AU2021226415A1
(en)
|
2020-02-28 |
2022-09-15 |
Pioneer Hi-Bred International, Inc. |
Sorghum doubled haploid production system
|
KR20230004456A
(ko)
|
2020-03-04 |
2023-01-06 |
리제너론 파아마슈티컬스, 인크. |
면역 요법에 대한 종양 세포의 감작화를 위한 방법 및 조성물
|
WO2021183636A1
(en)
|
2020-03-10 |
2021-09-16 |
Calyxt, Inc. |
Transformation and regeneration of cannabaceae
|
CN116096886A
(zh)
|
2020-03-11 |
2023-05-09 |
欧米茄治疗公司 |
用于调节叉头框p3(foxp3)基因表达的组合物和方法
|
WO2021193865A1
(ja)
|
2020-03-26 |
2021-09-30 |
国立研究開発法人農業・食品産業技術総合研究機構 |
温度感受性雄性不稔植物の製造方法
|
WO2021191870A1
(en)
|
2020-03-27 |
2021-09-30 |
Dcprime B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
WO2021202648A1
(en)
|
2020-03-31 |
2021-10-07 |
Calyxt, Inc. |
Agrobacterium-mediated infiltration of cannabaceae
|
US20230263121A1
(en)
|
2020-03-31 |
2023-08-24 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
CN116096902A
(zh)
|
2020-04-09 |
2023-05-09 |
R·J·雷诺兹烟草公司 |
用于调节烟草中尼古丁水平的方法
|
NL2025344B1
(en)
|
2020-04-14 |
2021-10-26 |
Academisch Ziekenhuis Leiden |
Methods for induction of endogenous tandem duplication events
|
US20230165205A1
(en)
|
2020-04-14 |
2023-06-01 |
ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) |
Methods for induction of endogenous tandem duplication events
|
US20210332388A1
(en)
|
2020-04-24 |
2021-10-28 |
Inscripta, Inc. |
Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
|
CN115803435A
(zh)
|
2020-05-06 |
2023-03-14 |
塞勒克提斯公司 |
用于在细胞基因组中靶向插入外源序列的方法
|
US20230193212A1
(en)
|
2020-05-06 |
2023-06-22 |
Orchard Therapeutics (Europe) Limited |
Treatment for neurodegenerative diseases
|
US20230279440A1
(en)
|
2020-05-06 |
2023-09-07 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
DE112021002672T5
(de)
|
2020-05-08 |
2023-04-13 |
President And Fellows Of Harvard College |
Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz
|
WO2021231259A1
(en)
|
2020-05-11 |
2021-11-18 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
US11787841B2
(en)
|
2020-05-19 |
2023-10-17 |
Inscripta, Inc. |
Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
|
UY39237A
(es)
|
2020-05-29 |
2021-12-31 |
Kws Saat Se & Co Kgaa |
Inducción de haploides en plantas
|
WO2021245435A1
(en)
|
2020-06-03 |
2021-12-09 |
Vilmorin & Cie |
Melon plants resistant to scab disease, aphids and powdery mildew
|
JP2023530234A
(ja)
|
2020-06-05 |
2023-07-14 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
新生物を治療するための組成物および方法
|
AU2021285274A1
(en)
|
2020-06-05 |
2023-02-02 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the TOBRFV
|
WO2021260139A1
(en)
|
2020-06-25 |
2021-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment and diagnostic of pathological conditions associated with intense stress
|
BR112022026128A2
(pt)
|
2020-07-14 |
2023-01-24 |
Kws Saat Se & Co Kgaa |
Métodos para identificar e selecionar plantas de milho com resistência à mangra da folha do milho do norte
|
AU2021204717A1
(en)
|
2020-07-15 |
2022-02-03 |
Seminis Vegetable Seeds, Inc. |
Green Bean Plants with Improved Disease Resistance
|
AU2021308681A1
(en)
|
2020-07-16 |
2023-03-09 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
KR20230074713A
(ko)
|
2020-07-30 |
2023-05-31 |
엥스띠뛰 퀴리 |
Socs1에 결함이 있는 면역 세포
|
WO2022035793A1
(en)
|
2020-08-10 |
2022-02-17 |
Precision Biosciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
EP4204545A2
(de)
|
2020-08-25 |
2023-07-05 |
Kite Pharma, Inc. |
T-zellen mit verbesserter funktionalität
|
CN116529266A
(zh)
|
2020-08-31 |
2023-08-01 |
耶鲁大学 |
用于将核酸递送到细胞的组合物和方法
|
CN116134141A
(zh)
|
2020-09-04 |
2023-05-16 |
国立大学法人神户大学 |
包含小型化胞苷脱氨酶的双链dna修饰用复合体
|
WO2022049273A1
(en)
|
2020-09-07 |
2022-03-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment of inflammatory bowel diseases
|
EP4214314A4
(de)
|
2020-09-15 |
2024-10-16 |
Inscripta Inc |
Crispr-editierung zum einbetten von nukleinsäurelandepads in genome von lebenden zellen
|
EP3971295A1
(de)
|
2020-09-16 |
2022-03-23 |
FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. |
Verfahren zur herstellung von genomeditierten pflanzen
|
US20220090012A1
(en)
|
2020-09-23 |
2022-03-24 |
Crispr Therapeutics Ag |
Genetically engineered t cells with regnase-1 and/or tgfbrii disruption have improved functionality and persistence
|
CA3193099A1
(en)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Prime editing guide rnas, compositions thereof, and methods of using the same
|
EP4221492A1
(de)
|
2020-10-02 |
2023-08-09 |
Vilmorin & Cie |
Melone mit verlängerter haltbarkeit
|
US20230365995A1
(en)
|
2020-10-07 |
2023-11-16 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
WO2022087527A1
(en)
|
2020-10-23 |
2022-04-28 |
Elo Life Systems, Inc. |
Methods for producing vanilla plants with improved flavor and agronomic production
|
CN116917502A
(zh)
|
2020-11-06 |
2023-10-20 |
Inserm(法国国家健康医学研究院) |
诊断和治疗多囊卵巢综合征(pcos)的方法
|
US20230416709A1
(en)
|
2020-11-06 |
2023-12-28 |
Editforce, Inc. |
Foki nuclease domain mutant
|
US11512297B2
(en)
|
2020-11-09 |
2022-11-29 |
Inscripta, Inc. |
Affinity tag for recombination protein recruitment
|
JP2023548979A
(ja)
|
2020-11-10 |
2023-11-21 |
インダストリアル マイクロブス, インコーポレイテッド |
供給原料からポリ(hiba)を産生可能な微生物
|
IL302983A
(en)
|
2020-11-20 |
2023-07-01 |
Revivicor Inc |
Multitransgenic pigs with growth hormone receptor silencing for xenotransplantation
|
EP4251282A1
(de)
|
2020-11-27 |
2023-10-04 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Verfahren zur diagnose und überwachung von toxischer epidermaler nekrolyse
|
EP4251746A1
(de)
|
2020-11-30 |
2023-10-04 |
Cellectis SA |
Verwendung von aminochinolinverbindungen zur höheren genintegration
|
JP2023553419A
(ja)
|
2020-12-03 |
2023-12-21 |
センチュリー セラピューティクス,インコーポレイテッド |
遺伝子操作細胞およびその使用
|
WO2022117884A1
(en)
|
2020-12-03 |
2022-06-09 |
Vilmorin & Cie |
Tomato plants resistant to tobrfv, tmv, tomv and tommv and corresponding resistance genes
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
EP4019639A1
(de)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Förderung der regeneration und transformation in beta vulgaris
|
EP4019638A1
(de)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Förderung der regeneration und transformation in beta vulgaris
|
WO2022137181A1
(en)
|
2020-12-23 |
2022-06-30 |
Crispr Therapeutics Ag |
Co-use of lenalidomide with car-t cells
|
US20240316090A1
(en)
|
2020-12-28 |
2024-09-26 |
Arcturus Therapeutics, Inc. |
Transcription activator-like effector nucleases (talens) targeting hbv
|
EP4271802A1
(de)
|
2021-01-04 |
2023-11-08 |
Inscripta, Inc. |
Mad-nukleasen
|
US11332742B1
(en)
|
2021-01-07 |
2022-05-17 |
Inscripta, Inc. |
Mad nucleases
|
AU2022206476A1
(en)
|
2021-01-11 |
2023-07-20 |
President And Fellows Of Harvard College |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|
AU2022207981A1
(en)
|
2021-01-12 |
2023-07-27 |
March Therapeutics, Inc. |
Context-dependent, double-stranded dna-specific deaminases and uses thereof
|
EP4284823A1
(de)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation der tgf-beta-signalisierung in genetisch modifizierten eukaryotischen zellen
|
US11884924B2
(en)
|
2021-02-16 |
2024-01-30 |
Inscripta, Inc. |
Dual strand nucleic acid-guided nickase editing
|
US20220288122A1
(en)
|
2021-03-09 |
2022-09-15 |
Crispr Therapeutics Ag |
Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity
|
JP2024510989A
(ja)
|
2021-03-12 |
2024-03-12 |
メンドゥス・ベスローテン・フェンノートシャップ |
ワクチン接種方法及びcd47遮断薬の使用
|
WO2022198107A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalain in cannabaceae plant parts
|
WO2022198106A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalains using plant cell matrices
|
WO2022198093A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin using plant cell matrices
|
WO2022198094A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin in cannabaceae plant parts
|
US20240191245A1
(en)
|
2021-03-18 |
2024-06-13 |
Calyxt, Inc. |
Plant cell matrices and methods thereof
|
WO2022208489A1
(en)
|
2021-04-02 |
2022-10-06 |
Vilmorin & Cie |
Semi-determinate or determinate growth habit trait in cucurbita
|
WO2022216514A1
(en)
|
2021-04-07 |
2022-10-13 |
Century Therapeutics, Inc. |
Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells
|
JP2024513906A
(ja)
|
2021-04-07 |
2024-03-27 |
センチュリー セラピューティクス,インコーポレイテッド |
人工多能性幹細胞からアルファ-ベータt細胞を生成するための組成物および方法
|
CN117479952A
(zh)
|
2021-04-07 |
2024-01-30 |
世纪治疗股份有限公司 |
用于嵌合抗原受体细胞的组合的人工细胞死亡/报告系统多肽及其用途
|
WO2022218998A1
(en)
|
2021-04-13 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for treating hepatitis b and d virus infection
|
US20240141311A1
(en)
|
2021-04-22 |
2024-05-02 |
North Carolina State University |
Compositions and methods for generating male sterile plants
|
JP2024515715A
(ja)
|
2021-04-23 |
2024-04-10 |
ユニバーシティ オブ ロチェスター |
レトロウイルスインテグラーゼ-Cas融合タンパク質を使用した指向性非相同DNA挿入によるゲノム編集及び治療の方法
|
CA3216563A1
(en)
|
2021-04-30 |
2022-11-03 |
Beatriz Aranda-Orgilles |
New anti-muc1 cars and gene edited immune cells for solid tumors cancer immunotherapy
|
US20240247285A1
(en)
|
2021-05-10 |
2024-07-25 |
Sqz Biotechnologies Company |
Methods for delivering genome editing molecules to the nucleus or cytosol of a cell and uses thereof
|
WO2022251644A1
(en)
|
2021-05-28 |
2022-12-01 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
EP4347826A1
(de)
|
2021-06-02 |
2024-04-10 |
Lyell Immunopharma, Inc. |
Nr4a3-defiziente immunzellen und verwendungen davon
|
US20230045095A1
(en)
|
2021-06-23 |
2023-02-09 |
Massachusetts Institute Of Technology |
Compositions, Methods and Systems for the Delivery of Gene Editing Material to Cells
|
CA3225278A1
(en)
|
2021-07-07 |
2023-01-12 |
Robert W. Williams |
Transcription activator-like effectors fused to inteins
|
EP4367242A2
(de)
|
2021-07-07 |
2024-05-15 |
Omega Therapeutics, Inc. |
Zusammensetzungen und verfahren zur modulation der genexpression des sekretierten frizzled-rezeptorproteins 1 (sfrp1)
|
CN118368974A
(zh)
|
2021-07-30 |
2024-07-19 |
科沃施种子欧洲股份两合公司 |
具有提高的消化率和标记单倍型的植物
|
IL310564A
(en)
|
2021-08-06 |
2024-03-01 |
Vilmorin & Cie |
Resistance to Leveillula Taurica in pepper plant
|
JP7125727B1
(ja)
|
2021-09-07 |
2022-08-25 |
国立大学法人千葉大学 |
核酸配列改変用組成物および核酸配列の標的部位を改変する方法
|
US20230128917A1
(en)
|
2021-09-14 |
2023-04-27 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having a disrupted cd83 gene
|
AU2022345694A1
(en)
|
2021-09-17 |
2024-05-02 |
Cibus Europe B.V. |
Transforming cannabaceae cells
|
AU2022347161A1
(en)
|
2021-09-20 |
2024-04-04 |
Revivicor, Inc. |
Multitransgenic pigs comprising ten genetic modifications for xenotransplantation
|
GB202113933D0
(en)
|
2021-09-29 |
2021-11-10 |
Genome Res Ltd |
Methods for gene editing
|
US20230141563A1
(en)
|
2021-10-12 |
2023-05-11 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating anti-viral transfer vector igm responses
|
KR20240082391A
(ko)
|
2021-10-14 |
2024-06-10 |
론자 세일즈 아게 |
세포외 소포 생산을 위한 변형된 생산자 세포
|
AU2022366987A1
(en)
|
2021-10-14 |
2024-05-16 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
AU2022371430A1
(en)
|
2021-10-19 |
2024-05-30 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
US20230226116A1
(en)
|
2021-10-20 |
2023-07-20 |
University Of Rochester |
Method for rejuvenating glial progenitor cells and rejuvenated glial progenitor cells per se
|
WO2023070043A1
(en)
|
2021-10-20 |
2023-04-27 |
Yale University |
Compositions and methods for targeted editing and evolution of repetitive genetic elements
|
EP4419685A1
(de)
|
2021-10-20 |
2024-08-28 |
University of Rochester |
Zusammensetzungen und verfahren zur behandlung von myelinmangel durch verjüngung glialer vorläuferzellen
|
CA3234231A1
(en)
|
2021-10-21 |
2023-04-27 |
Vertex Pharmaceuticals Incorporated |
Hypoimmune cells
|
WO2023081923A1
(en)
|
2021-11-08 |
2023-05-11 |
Frequency Therapeutics, Inc. |
Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
|
EP4430206A1
(de)
|
2021-11-10 |
2024-09-18 |
Encodia, Inc. |
Verfahren zur barcodierung von makromolekülen in einzelnen zellen
|
WO2023091910A1
(en)
|
2021-11-16 |
2023-05-25 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
CA3238700A1
(en)
|
2021-11-23 |
2022-11-23 |
Philippe Duchateau |
New tale protein scaffolds with improved on-target/off-target activity ratios
|
EP4437092A1
(de)
|
2021-11-26 |
2024-10-02 |
Epigenic Therapeutics Inc. |
Verfahren zur modulation von pcsk9 und verwendungen davon
|
GB202117314D0
(en)
|
2021-11-30 |
2022-01-12 |
Clarke David John |
Cyclic nucleic acid fragmentation
|
EP4441208A1
(de)
|
2021-11-30 |
2024-10-09 |
Pioneer Hi-Bred International, Inc. |
Hocheffiziente grossflächige chromosomale genommanipulation
|
AU2022400961A1
(en)
|
2021-12-03 |
2024-05-30 |
President And Fellows Of Harvard College |
Self-assembling virus-like particles for delivery of nucleic acid programmable fusion proteins and methods of making and using same
|
KR20240130158A
(ko)
|
2021-12-03 |
2024-08-28 |
더 브로드 인스티튜트, 인코퍼레이티드 |
효율적인 생체내 전달을 위한 조성물 및 방법
|
US20230193310A1
(en)
|
2021-12-10 |
2023-06-22 |
Seminis Vegetabe Seeds, Inc. |
Lettuce plants having resistance to downy mildew
|
GB202118058D0
(en)
|
2021-12-14 |
2022-01-26 |
Univ Warwick |
Methods to increase yields in crops
|
WO2023111913A1
(en)
|
2021-12-15 |
2023-06-22 |
Crispr Therapeutics Ag |
Engineered anti-liv1 cell with regnase-1 and/or tgfbrii disruption
|
EP4450634A1
(de)
|
2021-12-15 |
2024-10-23 |
Nanjing GenScript Biotech Co., Ltd. |
Verfahren zur erkennung einer integrationsstelle
|
KR20240122535A
(ko)
*
|
2021-12-17 |
2024-08-12 |
제니퍼 엠. 쉐론 |
바이러스의 재조합에 내성이 있는 반복 서열을 암호화하는 핵산 서열
|
US20230346836A1
(en)
|
2021-12-22 |
2023-11-02 |
Crispr Therapeutics Ag |
Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof
|
WO2023126458A1
(en)
|
2021-12-28 |
2023-07-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
WO2023129937A1
(en)
|
2021-12-29 |
2023-07-06 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof
|
WO2023129974A1
(en)
|
2021-12-29 |
2023-07-06 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
WO2023150557A1
(en)
|
2022-02-01 |
2023-08-10 |
University Of Rochester |
Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods
|
WO2023150553A1
(en)
|
2022-02-01 |
2023-08-10 |
University Of Rochester |
Gpr17 promoter-based targeting and transduction of glial progenitor cells
|
KR20240132132A
(ko)
|
2022-02-03 |
2024-09-02 |
니코벤처스 트레이딩 리미티드 |
담배 식물들에서 알칼로이드 함량을 조절하는 방법
|
AU2023215810A1
(en)
|
2022-02-03 |
2024-08-15 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
MX2024009605A
(es)
|
2022-02-04 |
2024-08-14 |
Nicoventures Trading Ltd |
Metodo para modular el contenido de alcaloides en plantas de tabaco.
|
AU2023221961A1
(en)
|
2022-02-16 |
2024-09-26 |
Dana-Farber Cancer Institute, Inc. |
Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereof
|
WO2023166425A1
(en)
|
2022-03-01 |
2023-09-07 |
Crispr Therapeutics Ag |
Methods and compositions for treating angiopoietin-like 3 (angptl3) related conditions
|
US20230357437A1
(en)
|
2022-03-09 |
2023-11-09 |
Selecta Biosciences, Inc. |
Immunosuppressants in combination with anti-igm agents and related dosing
|
WO2023180904A1
(en)
|
2022-03-21 |
2023-09-28 |
Crispr Therapeutics Ag |
Methods and compositions for treating lipoprotein-related diseases
|
US20230331841A1
(en)
|
2022-03-23 |
2023-10-19 |
Crispr Therapeutics Ag |
Anti-cd83 car-t cells with regnase-1 and/or tgfbrii disruption
|
US20230303713A1
(en)
|
2022-03-23 |
2023-09-28 |
Crispr Therapeutics Ag |
Anti-cd19 car-t cells with multiple gene edits and therapeutic uses thereof
|
EP4256950A1
(de)
|
2022-04-06 |
2023-10-11 |
Vilmorin et Cie |
Toleranz gegenüber cgmmv in gurken
|
GB202205148D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
GB202205149D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
GB202205562D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
GB202205561D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
GB202206109D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
GB202206107D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
WO2023213831A1
(en)
|
2022-05-02 |
2023-11-09 |
Fondazione Telethon Ets |
Homology independent targeted integration for gene editing
|
WO2023220603A1
(en)
|
2022-05-09 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Vectors and methods for in vivo antibody production
|
WO2023225665A1
(en)
|
2022-05-19 |
2023-11-23 |
Lyell Immunopharma, Inc. |
Polynucleotides targeting nr4a3 and uses thereof
|
EP4279085A1
(de)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Zusammensetzungen und verfahren zum behandeln eines refraktären oder rezidivierenden krebses oder einer chronischen infektionskrankheit
|
EP4278891A1
(de)
|
2022-05-20 |
2023-11-22 |
KWS SAAT SE & Co. KGaA |
Kohlhernienresistenz und marker in brassica
|
GB202207774D0
(en)
|
2022-05-26 |
2022-07-13 |
Cambridge Entpr Ltd |
Modified plants
|
WO2023240212A2
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
|
WO2023240147A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells expressing cd16 variants and nkg2d and uses thereof
|
WO2023240169A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof
|
WO2023242827A2
(en)
|
2022-06-17 |
2023-12-21 |
Crispr Therapeutics Ag |
LIPID NANOPARTICLES (LNPs)-BASED OCULAR DELIVERY
|
WO2023248147A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Methods and compositions for in vivo editing of stem cells
|
US20230404003A1
(en)
|
2022-06-21 |
2023-12-21 |
Seminis Vegetable Seeds, Inc. |
Novel qtls conferring resistance to cucumber mosaic virus
|
WO2023248145A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Compositions and methods for treating human immunodeficiency virus
|
WO2024003786A1
(en)
|
2022-06-29 |
2024-01-04 |
Crispr Therapeutics Ag |
Chimeric antigen receptor targeting gpc-3 and immune cells expressing such for therapeutic uses
|
GB2621813A
(en)
|
2022-06-30 |
2024-02-28 |
Univ Newcastle |
Preventing disease recurrence in Mitochondrial replacement therapy
|
WO2024020360A1
(en)
|
2022-07-18 |
2024-01-25 |
Pairwise Plants Services, Inc. |
Mustard green plants named 'pwrg-1', 'pwrg-2,' and 'pwsgc'
|
WO2024020597A1
(en)
|
2022-07-22 |
2024-01-25 |
The Johns Hopkins University |
Dendrimer-enabled targeted intracellular crispr/cas system delivery and gene editing
|
WO2024023801A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene
|
WO2024023804A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene
|
WO2024026474A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle
|
WO2024023802A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene
|
LU502613B1
(en)
|
2022-08-01 |
2024-02-01 |
Plant Bioscience Ltd |
Methods of altering the starch granule profile in plants
|
WO2024031053A1
(en)
|
2022-08-05 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
Aggregation-resistant variants of tdp-43
|
WO2024042199A1
(en)
|
2022-08-26 |
2024-02-29 |
KWS SAAT SE & Co. KGaA |
Use of paired genes in hybrid breeding
|
WO2024062388A2
(en)
|
2022-09-20 |
2024-03-28 |
Crispr Therapeutics Ag |
Genetically engineered immune cells expressing chimeric antigen receptor targeting cd20
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
WO2024064958A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
WO2024064952A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells overexpressing c-jun
|
GB202214410D0
(en)
|
2022-09-30 |
2022-11-16 |
Ivy Farm Tech Limited |
genetically modified cells
|
WO2024077174A1
(en)
|
2022-10-05 |
2024-04-11 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
WO2024081736A2
(en)
|
2022-10-11 |
2024-04-18 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
WO2024079157A1
(en)
|
2022-10-11 |
2024-04-18 |
KWS SAAT SE & Co. KGaA |
Virus and insect resistance and markers in barley
|
WO2024084025A1
(en)
|
2022-10-21 |
2024-04-25 |
Keygene N.V. |
Rna transfection in plant cells with modified rna
|
WO2024102838A1
(en)
|
2022-11-09 |
2024-05-16 |
Century Therapeutics, Inc. |
Engineered interleukin-7 receptors and uses thereof
|
WO2024103017A2
(en)
|
2022-11-10 |
2024-05-16 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-nectin4 chimeric antigen receptors, and uses thereof
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
WO2024108092A1
(en)
|
2022-11-17 |
2024-05-23 |
The Broad Institute, Inc. |
Prime editor delivery by aav
|
WO2024119101A1
(en)
|
2022-12-01 |
2024-06-06 |
Yale University |
Stimuli-responsive traceless engineering platform for intracellular payload delivery
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
WO2024121354A1
(en)
|
2022-12-08 |
2024-06-13 |
Keygene N.V. |
Duplex sequencing with covalently closed dna ends
|
WO2024138087A2
(en)
|
2022-12-23 |
2024-06-27 |
The Broad Institute, Inc. |
Methods and compositions for modulating cellular factors to increase prime editing efficiencies
|
GB202219829D0
(en)
|
2022-12-29 |
2023-02-15 |
Ivy Farm Tech Limited |
Genetically manipulated cells
|
WO2024141599A1
(en)
|
2022-12-29 |
2024-07-04 |
Vilmorin & Cie |
Tomato plants resistant to resistance-breaking tswv strains and corresponding resistance genes
|
WO2024155745A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Base editing-mediated readthrough of premature termination codons (bert)
|
WO2024155741A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Prime editing-mediated readthrough of premature termination codons (pert)
|
GB202300905D0
(en)
|
2023-01-20 |
2023-03-08 |
Nicoventures Trading Ltd |
Method
|
WO2024161358A1
(en)
|
2023-02-01 |
2024-08-08 |
Dlf Seeds A/S |
Beet yellows virus resistance
|
WO2024170505A1
(en)
|
2023-02-13 |
2024-08-22 |
Institut National de la Santé et de la Recherche Médicale |
Methods of treatment of iron overload associated diseases
|
WO2024173645A1
(en)
|
2023-02-15 |
2024-08-22 |
Arbor Biotechnologies, Inc. |
Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript
|
GB202303077D0
(en)
|
2023-03-02 |
2023-04-19 |
Univ Oslo |
Brassica plants with improved seed retention
|
WO2024192108A1
(en)
|
2023-03-14 |
2024-09-19 |
Evolveimmune Therapeutics, Inc. |
Genetically modified car t cells and methods of making and using the same
|
WO2024206821A1
(en)
|
2023-03-31 |
2024-10-03 |
Briacell Therapeutics Corp. |
Methods for enhancing the immunogenicity of cellular vaccines
|
WO2024209000A1
(en)
|
2023-04-04 |
2024-10-10 |
Keygene N.V. |
Linkers for duplex sequencing
|
EP4445723A1
(de)
|
2023-04-14 |
2024-10-16 |
Seminis Vegetable Seeds, Inc. |
Verfahren und zusammensetzungen für peronsporaresistenz in spinat
|